{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:40:43Z","timestamp":1790876443125,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"National Mega Project on Major Drug Development","award":["2009ZX09301-014-1"],"award-info":[{"award-number":["2009ZX09301-014-1"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1016\/j.jep.2013.08.056","type":"journal-article","created":{"date-parts":[[2013,9,17]],"date-time":"2013-09-17T02:49:09Z","timestamp":1379386149000},"page":"521-528","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":45,"title":["Jiawei-Yupingfeng-Tang, a Chinese herbal formula, inhibits respiratory viral infections in vitro and in vivo"],"prefix":"10.1016","volume":"150","author":[{"given":"Qiang","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moli","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hairong","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhanqiu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2013.08.056_bib1","doi-asserted-by":"crossref","first-page":"7359","DOI":"10.4049\/jimmunol.174.11.7359","article-title":"Respiratory syncytial virus infection of human lung endothelial cells enhances selectively intercellular adhesion molecule-1 expression","volume":"174","author":"Arnold","year":"2005","journal-title":"The Journal of Immunology"},{"key":"10.1016\/j.jep.2013.08.056_bib2","doi-asserted-by":"crossref","first-page":"236539","DOI":"10.1155\/2012\/236539","article-title":"Sarcandra glabra extract reduces the susceptibility and severity of influenza in restraint-stressed mice","volume":"2012","author":"Cao","year":"2012","journal-title":"Evidence-Based Complementary and Alternative Medicine"},{"key":"10.1016\/j.jep.2013.08.056_bib3","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.rvsc.2013.04.013","article-title":"In vitro inhibition of canine distemper virus by flavonoids and phenolic acids: implications of structural differences for antiviral design","volume":"95","author":"Carvalho","year":"2013","journal-title":"Research in Veterinary Science"},{"key":"10.1016\/j.jep.2013.08.056_bib4","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.jep.2011.11.018","article-title":"Ge-Gen-Tang has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines","volume":"139","author":"Chang","year":"2012","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2013.08.056_bib5","doi-asserted-by":"crossref","first-page":"3346","DOI":"10.1128\/AAC.00211-07","article-title":"RSV604, a novel inhibitor of respiratory syncytial virus replication","volume":"51","author":"Chapman","year":"2007","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jep.2013.08.056_bib6","series-title":"Chinese Herbal Formulas and Applications: Pharmacological Effects & Clinical Research","author":"Chen","year":"2009"},{"key":"10.1016\/j.jep.2013.08.056_bib7","first-page":"302","article-title":"The regulatory action of the modified Yu Ping Feng Tang on cellular immunity in mice under amputation-induced stress","volume":"20","author":"Chen","year":"2000","journal-title":"Journal of Traditional Chinese Medicine"},{"key":"10.1016\/j.jep.2013.08.056_bib8","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1146\/annurev.med.51.1.407","article-title":"Global epidemiology of influenza: past and present","volume":"51","author":"Cox","year":"2000","journal-title":"Annual Review of Medicine"},{"key":"10.1016\/j.jep.2013.08.056_bib9","series-title":"Fields Virology","author":"Fields","year":"2007"},{"key":"10.1016\/j.jep.2013.08.056_bib10","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/j.cyto.2013.01.008","article-title":"Astragaloside IV ameliorates renal injury in streptozotocin-induced diabetic rats through inhibiting NF-kappaB-mediated inflammatory genes expression","volume":"63","author":"Gui","year":"2013","journal-title":"Cytokine"},{"key":"10.1016\/j.jep.2013.08.056_bib11","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jcv.2008.10.001","article-title":"Differential patterns of amantadine-resistance in influenza A (H3N2) and (H1N1) isolates in Toronto, Canada","volume":"44","author":"Higgins","year":"2009","journal-title":"Journal of Clinical Virology"},{"key":"10.1016\/j.jep.2013.08.056_bib12","doi-asserted-by":"crossref","first-page":"3068","DOI":"10.1016\/S0264-410X(02)00254-2","article-title":"Realities and enigmas of human viral influenza: pathogenesis, epidemiology and control","volume":"20","author":"Hilleman","year":"2002","journal-title":"Vaccine"},{"key":"10.1016\/j.jep.2013.08.056_bib13","first-page":"109","article-title":"Effect of jiawei yupingfeng powder on T-lymphocyte subsets in patients with senile chronic bronchitis in acute onset stage","volume":"24","author":"Huang","year":"2004","journal-title":"Zhongguo Zhongxiyi Jiehe Zazhi"},{"key":"10.1016\/j.jep.2013.08.056_bib14","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.toxlet.2006.01.015","article-title":"Effect of diesel exhaust particles on mRNA expression of viral and bacterial receptors in rat lung epithelial L2 cells","volume":"165","author":"Ito","year":"2006","journal-title":"Toxicology Letters"},{"key":"10.1016\/j.jep.2013.08.056_bib15","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.bbrc.2011.10.115","article-title":"Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells","volume":"415","author":"Kim","year":"2011","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"10.1016\/j.jep.2013.08.056_bib16","first-page":"426","article-title":"Experimental study on effect of jiawei yupingfeng san on microcirculation and plasma superoxide dismutase activity in old mice","volume":"13","author":"Li","year":"1993","journal-title":"Zhongguo Zhongxiyi Jiehe Zazhi"},{"key":"10.1016\/j.jep.2013.08.056_bib17","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.neuint.2012.01.026","article-title":"Astragaloside IV protects against focal cerebral ischemia\/reperfusion injury correlating to suppression of neutrophils adhesion-related molecules","volume":"60","author":"Li","year":"2012","journal-title":"Neurochemistry International"},{"key":"10.1016\/j.jep.2013.08.056_bib18","doi-asserted-by":"crossref","first-page":"4386","DOI":"10.1128\/JVI.01492-10","article-title":"Hydrolyzable tannins (chebulagic acid and punicalagin) target viral glycoprotein-glycosaminoglycan interactions to inhibit herpes simplex virus 1 entry and cell-to-cell spread","volume":"85","author":"Lin","year":"2011","journal-title":"Journal of Virology"},{"key":"10.1016\/j.jep.2013.08.056_bib19","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.neulet.2004.03.036","article-title":"Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia","volume":"363","author":"Luo","year":"2004","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.jep.2013.08.056_bib20","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1590\/S1807-59322010001100004","article-title":"Oseltamivir compounding in the hospital pharmacy during the (H1N1) influenza pandemic","volume":"65","author":"Marin","year":"2010","journal-title":"Clinics (Sao Paulo)"},{"key":"10.1016\/j.jep.2013.08.056_bib21","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jviromet.2004.02.020","article-title":"A simplified plaque assay for respiratory syncytial virus\u2013direct visualization of plaques without immunostaining","volume":"120","author":"McKimm-Breschkin","year":"2004","journal-title":"Journal of Virological Methods"},{"key":"10.1016\/j.jep.2013.08.056_bib22","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1128\/CMR.00045-07","article-title":"Respiratory viruses other than influenza virus: impact and therapeutic advances","volume":"21","author":"Nichols","year":"2008","journal-title":"Clinical Microbiology Reviews"},{"key":"10.1016\/j.jep.2013.08.056_bib23","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.jep.2010.10.057","article-title":"Korean Scutellaria baicalensis water extract inhibits cell cycle G1\/S transition by suppressing cyclin D1 expression and matrix-metalloproteinase-2 activity in human lung cancer cells","volume":"133","author":"Park","year":"2011","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2013.08.056_bib24","first-page":"247","article-title":"Cell damage by viruses, toxins and complement: common features of pore-formation and its inhibition by Ca2+","volume":"50","author":"Pasternak","year":"1985","journal-title":"Biochemical Society Symposium"},{"key":"10.1016\/j.jep.2013.08.056_bib25","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1096\/fj.07-9574LSF","article-title":"Dose translation from animal to human studies revisited","volume":"22","author":"Reagan-Shaw","year":"2008","journal-title":"FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology"},{"key":"10.1016\/j.jep.2013.08.056_bib26","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.jcv.2011.05.019","article-title":"Emerging oseltamivir resistance in seasonal and pandemic influenza A\/H1N1","volume":"52","author":"Renaud","year":"2011","journal-title":"Journal of Clinical Virology"},{"key":"10.1016\/j.jep.2013.08.056_bib27","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.phymed.2012.12.001","article-title":"Hesperidin attenuates cisplatin-induced acute renal injury by decreasing oxidative stress, inflammation and DNA damage","volume":"20","author":"Sahu","year":"2013","journal-title":"Phytomedicine: International Journal of Phytotherapy and Phytopharmacology"},{"key":"10.1016\/j.jep.2013.08.056_bib28","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1002\/ptr.2868","article-title":"Antiviral activity and mode of action of propolis extracts and selected compounds","volume":"24","author":"Schnitzler","year":"2010","journal-title":"Phytotherapy Research: PTR"},{"key":"10.1016\/j.jep.2013.08.056_bib29","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1111\/j.2042-7158.2011.01258.x","article-title":"Astragaloside IV inhibits adenovirus replication and apoptosis in A549 cells in vitro","volume":"63","author":"Shang","year":"2011","journal-title":"The Journal of Pharmacy and Pharmacology"},{"key":"10.1016\/j.jep.2013.08.056_bib30","doi-asserted-by":"crossref","first-page":"e7788","DOI":"10.1371\/journal.pone.0007788","article-title":"Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein","volume":"4","author":"Triana-Baltzer","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2013.08.056_bib31","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.antiviral.2009.05.002","article-title":"Anti-hepatitis B virus activity of chlorogenic acid, quinic acid and caffeic acid in vivo and in vitro","volume":"83","author":"Wang","year":"2009","journal-title":"Antiviral Research"},{"key":"10.1016\/j.jep.2013.08.056_bib32","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.jep.2011.03.058","article-title":"Sheng-Ma-Ge-Gen-Tang (Shoma-kakkon-to) inhibited cytopathic effect of human respiratory syncytial virus in cell lines of human respiratory tract","volume":"135","author":"Wang","year":"2011","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2013.08.056_bib33","first-page":"742","article-title":"Clinical observation of effect of jiawei yupingfeng mixture for prevention and treatment of 100 children with repeated respiratory tract infection","volume":"29","author":"Wang","year":"2009","journal-title":"Zhongguo Zhongxiyi Jiehe Zazhi"},{"key":"10.1016\/j.jep.2013.08.056_bib34","doi-asserted-by":"crossref","first-page":"S133","DOI":"10.1086\/507548","article-title":"Prevention and treatment of influenza in high-risk groups: children, pregnant women, immunocompromised hosts, and nursing home residents","volume":"194","author":"Whitley","year":"2006","journal-title":"Journal of Infectious Disease"},{"key":"10.1016\/j.jep.2013.08.056_bib35","doi-asserted-by":"crossref","first-page":"e28901","DOI":"10.1371\/journal.pone.0028901","article-title":"Adaption of seasonal H1N1 influenza virus in mice","volume":"6","author":"Xu","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2013.08.056_bib36","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.ejphar.2010.09.056","article-title":"Procaterol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells","volume":"650","author":"Yamaya","year":"2011","journal-title":"European Journal of Pharmacology"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874113006272?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874113006272?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,13]],"date-time":"2018-10-13T01:58:43Z","timestamp":1539395923000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874113006272"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["S0378874113006272"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2013.08.056","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2013,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Jiawei-Yupingfeng-Tang, a Chinese herbal formula, inhibits respiratory viral infections in vitro and in vivo","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2013.08.056","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}