{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T12:00:10Z","timestamp":1783598410531,"version":"3.55.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Direcci\u00f3n General de Asuntos de Personal Acad\u00e9mico (DGAPA","award":["IN-212913"],"award-info":[{"award-number":["IN-212913"]}]},{"name":"Consejo Nacional de Ciencia y Tecnolog\u00eda (CONACyT","award":["150966"],"award-info":[{"award-number":["150966"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1016\/j.jep.2014.05.051","type":"journal-article","created":{"date-parts":[[2014,6,2]],"date-time":"2014-06-02T13:18:34Z","timestamp":1401715114000},"page":"416-425","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"title":["Hypoglycemic properties of some preparations and compounds from Artemisia ludoviciana Nutt"],"prefix":"10.1016","volume":"155","author":[{"given":"Gerardo D.","family":"Anaya-Eugenio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Rivero-Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Rivera-Ch\u00e1vez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Mata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2014.05.051_bib1","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1111\/j.1440-1681.1986.tb00940.x","article-title":"Treatment of diabetes mellitus by Artemisia herba-alba extract: preliminary study","volume":"13","author":"Al-Waili","year":"1986","journal-title":"Clinical and Experimental Pharmacology and Physiology"},{"key":"10.1016\/j.jep.2014.05.051_bib2","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0378-8741(98)00020-8","article-title":"Study of the anti-hyperglycemic effect of plants used as antidiabetics","volume":"61","author":"Alarc\u00f3n-Aguilar","year":"1998","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2014.05.051_bib3","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.jep.2005.04.019","article-title":"Mexican plants with hypoglycaemic effect used in the treatment of diabetes","volume":"99","author":"Andrade-Cetto","year":"2005","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2014.05.051_bib4","first-page":"628","volume":"Vol. II","author":"Argueta","year":"1994"},{"key":"10.1016\/j.jep.2014.05.051_bib5","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3109\/13880209.2010.497815","article-title":"The genus Artemisia: a comprehensive review","volume":"49","author":"Bora","year":"2010","journal-title":"Pharmaceutical Biology"},{"key":"10.1016\/j.jep.2014.05.051_bib6","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0014-5793(96)01502-5","article-title":"Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor \u03baB (NF-\u03baB)","volume":"402","author":"Bork","year":"1997","journal-title":"Federation of European Biochemical Societies Letters"},{"key":"10.1016\/j.jep.2014.05.051_bib7","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.jep.2006.05.025","article-title":"in vitro susceptibility of Entamoeba histolytica and Giardia lamblia to plants used in Mexican traditional medicine for the treatment of gastrointestinal disorders","volume":"108","author":"Calzada","year":"2006","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2014.05.051_bib8","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.jep.2008.12.021","article-title":"Anti-Helicobacter pylori activity of plants used in Mexican traditional medicine for gastrointestinal disorders","volume":"122","author":"Castillo-Ju\u00e1rez","year":"2009","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2014.05.051_bib9","doi-asserted-by":"crossref","first-page":"655","DOI":"10.3839\/jksabc.2009.109","article-title":"Inhibitory activity of caffeoylquinic acids from the aerial parts of Artemisia princeps on rat lens aldose reductase and on the formation of advanced glycation end products","volume":"52","author":"Cheng-Bi","year":"2009","journal-title":"Journal of the Korean Society for Applied Biochemical Chemistry"},{"key":"10.1016\/j.jep.2014.05.051_bib10","series-title":"Enzymes: A Practical Introduction to Structure, Mechanism, and Data Analysis","author":"Copeland","year":"2000"},{"key":"10.1016\/j.jep.2014.05.051_bib11","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1002\/ptr.3187","article-title":"Bioactivity-guided isolation of antiproliferative compounds from Centaurea arenaria","volume":"24","author":"Csapi","year":"2010","journal-title":"Phytotherapy Research"},{"key":"10.1016\/j.jep.2014.05.051_bib12","series-title":"M\u00e9xico","article-title":"Libellus de Medicinalibus Indorum Herbis, Ed., Fondo de Cultura Econ\u00f3mica","author":"De la Cruz","year":"1991"},{"key":"10.1016\/j.jep.2014.05.051_bib13","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1021\/np300204p","article-title":"\u03b1-Glucosidase inhibitors from Brickellia cavanillesii","volume":"75","author":"Escand\u00f3n-Rivera","year":"2012","journal-title":"Journal of Natural Products"},{"key":"10.1016\/j.jep.2014.05.051_bib14","article-title":"Florilegio Medicinal de Todas las Enfermedades, 5\u00aa","author":"Esteyneffer","year":"1732"},{"key":"10.1016\/j.jep.2014.05.051_bib15","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1080\/10286020903451757","article-title":"Constituents from the testas of Castanea mollissima Blume with \u03b1-glucosidase inhibitory activity","volume":"12","author":"Gao","year":"2010","journal-title":"Journal of Asian Natural Products Research"},{"key":"10.1016\/j.jep.2014.05.051_bib16","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s11274-005-9087-z","article-title":"Extracts of Acacia farnesiana and Artemisia ludoviciana inhibit growth, enterotoxin production and adhesion of Vibrio cholerae","volume":"22","author":"Garc\u00eda","year":"2006","journal-title":"World Journal of Microbiology and Biotechnology"},{"key":"10.1016\/j.jep.2014.05.051_bib17","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.diabres.2013.11.002","article-title":"Global estimates of diabetes prevalence for 2013 and projections for 2035","volume":"103","author":"Guariguata","year":"2014","journal-title":"Diabetes Research and Clinical Practice"},{"key":"10.1016\/j.jep.2014.05.051_bib18","unstructured":"Gyeong, M.Y., Sang, O.K., Bok, N.K., Jae, H.J., Chung, G.N., Seon, P.N., 2013. Prunellae spica and Artemisia argyi extracts for Inhibiting Protein Tyrosine Phosphatase. Repub. Korean Kongkae Taeho Kongbo. KR 2013055395A 20130528."},{"key":"10.1016\/j.jep.2014.05.051_bib19","series-title":"Mexicana (Estafiate)","first-page":"107","article-title":"Etnobotany, phytochemistry and biological\/pharmacological activities of Artemisia ludoviciana ssp","author":"Heinrich","year":"2002"},{"key":"10.1016\/j.jep.2014.05.051_bib20","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2147\/DMSO.S38753","article-title":"Drug treatment of type 2 diabetes mellitus in patients for whom metformin is contraindicated","volume":"7","author":"Irons","year":"2014","journal-title":"Diabetes, Metabolic Syndrome and Obesity"},{"key":"10.1016\/j.jep.2014.05.051_bib21","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1007\/s12272-013-0069-7","article-title":"Potent \u03b1-glucosidase and protein tyrosine phosphatase 1B inhibitors from Artemisia capillaris","volume":"36","author":"Islam","year":"2013","journal-title":"Archives of Pharmacal Research"},{"key":"10.1016\/j.jep.2014.05.051_bib22","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1002\/ptr.1377","article-title":"Activity against multidrug-resistant Mycobacterium tuberculosis in Mexican plants used to treat respiratory diseases","volume":"17","author":"Jim\u00e9nez-Arellanes","year":"2003","journal-title":"Phytotherapy Research"},{"key":"10.1016\/j.jep.2014.05.051_bib23","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1016\/j.fct.2007.04.021","article-title":"The anti-diabetic effects of ethanol extract from two variants of Artemisia princeps Pampanini in C57BL\/KsJ-db\/db mice","volume":"45","author":"Jung","year":"2007","journal-title":"Food and Chemical Toxicology"},{"key":"10.1016\/j.jep.2014.05.051_bib24","first-page":"A667","article-title":"Antihyperglycemic and antioxidant properties of jaceosidin, a flavonoid isolated from Artemisia princeps, in type 2 diabetic mice","volume":"56","author":"Kang","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.jep.2014.05.051_bib25","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.diabres.2008.06.012","article-title":"Eupatilin, isolated from Artemisia princeps Pampanini, enhances hepatic glucose metabolism and pancreatic \u03b2-cell function in type 2 diabetic mice","volume":"82","author":"Kang","year":"2008","journal-title":"Diabetes Research and Clinical Practice"},{"key":"10.1016\/j.jep.2014.05.051_bib26","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/703034","article-title":"Jaceosidin induces apoptosis in U87 glioblastoma cells through G2\/M phase arrest","author":"Khan","year":"2012","journal-title":"Evidence-Based Complementary and Alternative Medicine"},{"key":"10.1016\/j.jep.2014.05.051_bib27","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0031-9422(82)80045-9","article-title":"Flavonoids from Artemisia ludoviciana var. ludoviciana","volume":"21","author":"Liu","year":"1982","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jep.2014.05.051_bib28","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/BF01234480","article-title":"A new approach to partial acute toxicity testing","volume":"54","author":"Lorke","year":"1983","journal-title":"Archives of Toxicology"},{"key":"10.1016\/j.jep.2014.05.051_bib29","unstructured":"Masao, T., Yoshihiko, N., Takashi, T., Hiroshi, H., Atsuko, Y., 2013. Adiponectin Production Promoting Compositions Containing Aqueous Extract of Artemisia capillaris and Cosmetics, Health Food, and Pharmaceuticals Containing the Compositions. Jpn. Kokai Tokkyo Koho. JP 2013237658A 20131128."},{"key":"10.1016\/j.jep.2014.05.051_bib30","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1021\/np300869g","article-title":"Mexican antidiabetic herbs: valuable sources of inhibitors of \u03b1-glucosidases","volume":"76","author":"Mata","year":"2013","journal-title":"Journal of Natural Products"},{"key":"10.1016\/j.jep.2014.05.051_bib31","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1016\/S0031-9422(00)83464-0","article-title":"Sesquiterpene lactones of Artemisia mexicana var. angustifolia","volume":"23","author":"Mata","year":"1984","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jep.2014.05.051_bib32","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1248\/bpb.27.1797","article-title":"Strong antihyperglycemic effects of water-soluble fraction of brazilian propolis and its bioactive constituent, 3,4,5-tri-o-caffeoylquinic acid","volume":"27","author":"Matsui","year":"2004","journal-title":"Biological and Pharmaceutical Bulletin"},{"key":"10.1016\/j.jep.2014.05.051_bib33","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1002\/(SICI)1096-987X(19981115)19:14<1639::AID-JCC10>3.0.CO;2-B","article-title":"Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function","volume":"19","author":"Morris","year":"1998","journal-title":"Journal of Computational Chemistry"},{"key":"10.1016\/j.jep.2014.05.051_bib34","unstructured":"Myeong, S.C., Yeong, J.K., Seon, M.J., 2009. Eupatilin and Jaceosidin for Preventing and Treating Diabetes Mellitus. Repub. Korean Kongkae Taeho Kongbo. KR 2009066858A 20090624."},{"key":"10.1016\/j.jep.2014.05.051_bib35","first-page":"42","article-title":"Anti-diabetic effect of Artemisia judaica extracts","volume":"4","author":"Nofal","year":"2009","journal-title":"Research Journal of Medicine and Medical Sciences"},{"key":"10.1016\/j.jep.2014.05.051_bib36","doi-asserted-by":"crossref","first-page":"597","DOI":"10.2337\/db11-0396","article-title":"Bioactives of Artemisia dracunculus L. mitigate the role of ceramides in attenuating insulin signaling in rat skeletal muscle cells","volume":"61","author":"Obanda","year":"2012","journal-title":"Diabetes"},{"key":"10.1016\/j.jep.2014.05.051_bib37","unstructured":"Qunfang, C., Meizhu, F., Xiaoning, L., Yonghong, F., Yongxing, W., Xin, X., 2011. Application of Artemisia rupestris Preparation in Medicine for Treating Diabetes. Faming Zhuanli Shenqing CN 102166243A 20110831."},{"key":"10.1016\/j.jep.2014.05.051_bib38","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.phymed.2005.09.007","article-title":"Antihyperglycemic activity of Tarralin, an ethanolic extract of Artemisia dracunculus L","volume":"8","author":"Ribnicky","year":"2006","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2014.05.051_bib39","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.pbiomolbio.2011.06.009","article-title":"Electrophysiology of pancreatic \u03b2-cells in intact mouse islets of Langerhans","volume":"107","author":"Rorsman","year":"2011","journal-title":"Progress in Biophysics and Molecular Biology"},{"key":"10.1016\/j.jep.2014.05.051_bib40","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/bmb.20392","article-title":"Molecular docking of enzyme inhibitors","volume":"38","author":"Rudnitskaya","year":"2010","journal-title":"Biochemistry and Molecular Biology Education"},{"key":"10.1016\/j.jep.2014.05.051_bib41","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/0031-9422(93)85032-M","article-title":"Sesquiterpene lactones and flavonoids from Artemisia ludoviciana ssp. Mexicana","volume":"33","author":"Ruiz-Cancino","year":"1993","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jep.2014.05.051_bib42","unstructured":"Shuying, H., Zhilu, W., Jianxing, W., Jinxiu, C., Hong, J., Liping, W., 2011. Process for Manufacturing Extract of Artemisia annua for Controlling Postprandial Blood Sugar. Faming Zhuanli Shenqing CN 101933965A 20110105."},{"key":"10.1016\/j.jep.2014.05.051_bib43","series-title":"Traditional Medicines for Modern Times Antidiabetic Plants","first-page":"19","article-title":"Plants used in the treatment of diabetes","author":"Simmonds","year":"2006"},{"key":"10.1016\/j.jep.2014.05.051_bib44","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1021\/np50088a020","article-title":"New diterpenoids from Salvia divaricata","volume":"55","author":"Ulubelen","year":"1992","journal-title":"Journal of Natural Products"},{"key":"10.1016\/j.jep.2014.05.051_bib45","first-page":"229","article-title":"The cytotoxicity evaluation of seven species of Artemisia on human tumor cell lines","volume":"1","author":"Vahdati-Mashhadian","year":"2009","journal-title":"Pharmacologyonline"},{"key":"10.1016\/j.jep.2014.05.051_bib46","unstructured":"Whittle, B.A., Skett, P.G., 2002. Artemisia judaica Fractionation Method. Phytotech Limited. US 6350478 B1."},{"key":"10.1016\/j.jep.2014.05.051_bib47","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/ptr.4966","article-title":"Animal studies on medicinal herbs: predictability, dose conversion and potential value","volume":"28","author":"Wojcikowski","year":"2014","journal-title":"Phytotherapy Research"},{"key":"10.1016\/j.jep.2014.05.051_bib48","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.phymed.2010.07.005","article-title":"Hypoglycemic effect of Belamcanda chinensis leaf extract in normal and STZ-induced diabetic rats and its potential active fraction","volume":"18","author":"Wu","year":"2011","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2014.05.051_bib49","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.2174\/092986610792231492","article-title":"Inhibition kinetics of flavonoids on yeast-glucosidase merged with docking simulations","volume":"17","author":"Xu","year":"2010","journal-title":"Protein and Peptide Letters"},{"key":"10.1016\/j.jep.2014.05.051_bib50","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1076\/phbi.40.4.263.8465","article-title":"Antidiarrhoeal activity of nonanal, an aldehyde isolated from Artemisia ludoviciana","volume":"40","author":"Zavala-S\u00e1nchez","year":"2002","journal-title":"Pharmaceutical Biology"},{"key":"10.1016\/j.jep.2014.05.051_bib51","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1016\/j.jff.2013.04.008","article-title":"\u03b1-Glucosidase inhibitory activity by the flower buds of Lonicera japonica Thunb","volume":"5","author":"Zhang","year":"2013","journal-title":"Journal of Functional Foods"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874114004206?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874114004206?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T18:50:45Z","timestamp":1538592645000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874114004206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["S0378874114004206"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2014.05.051","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2014,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypoglycemic properties of some preparations and compounds from Artemisia ludoviciana Nutt","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2014.05.051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}