{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:18:35Z","timestamp":1791199115467,"version":"4.1.0"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,12,9]],"date-time":"2015-12-09T00:00:00Z","timestamp":1449619200000},"content-version":"vor","delay-in-days":342,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00c3\u00a7\u00c3\u00a3o de Amparo \u00c3\u00a0 Pesquisa do Estado de S\u00c3\u00a3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00c3\u00adfico e Tecnol\u00c3\u00b3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00c3\u00a7\u00c3\u00a3o de Aperfei\u00c3\u00a7oamento de Pessoal de N\u00c3\u00advel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00c3\u00adfico e Tecnol\u00c3\u00b3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00c3\u00a7\u00c3\u00a3o de Amparo \u00c3\u00a0 Pesquisa do Estado de S\u00c3\u00a3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.jep.2014.11.025","type":"journal-article","created":{"date-parts":[[2014,11,24]],"date-time":"2014-11-24T16:16:12Z","timestamp":1416845772000},"page":"285-295","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"special_numbering":"C","title":["Terminalia catappa L.: A medicinal plant from the Caribbean pharmacopeia with anti-Helicobacter pylori and antiulcer action in experimental rodent models"],"prefix":"10.1016","volume":"159","author":[{"given":"La\u00edsa","family":"Pinheiro Silva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9lio","family":"Damacena de Angelis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia","family":"Bonamin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9lio","family":"Kushima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Jos\u00e9 Mininel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lourdes","family":"Campaner dos Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia","family":"Karina Delella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Luis Felisbino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wagner","family":"Vilegas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Regina Machado da Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matheus","family":"Aparecido dos Santos Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tais","family":"Maria Bauab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walber","family":"Toma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clelia","family":"Akiko Hiruma-Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2014.11.025_bib1","doi-asserted-by":"crossref","first-page":"4168","DOI":"10.1021\/jf001494m","article-title":"Composition and antimicrobial activity of the essential oils of two Origanum species","volume":"49","author":"Aligannis","year":"2001","journal-title":"Journal of Agricultural and Food Chemistry"},{"key":"10.1016\/j.jep.2014.11.025_bib2","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1097\/MOG.0b013e328358d56c","article-title":"Gastroduodenal mucosal defense","volume":"28","author":"Al-Jiboury","year":"2012","journal-title":"Current Opinion of Gastroenterology"},{"key":"10.1016\/j.jep.2014.11.025_bib3","doi-asserted-by":"crossref","first-page":"4811","DOI":"10.3748\/wjg.v18.i35.4811","article-title":"Quality of ulcer healing in gastrointestinal tract: its pathophysiology and clinical relevance","volume":"18","author":"Arakawa","year":"2012","journal-title":"World Journal of Gastroenterology"},{"key":"10.1016\/j.jep.2014.11.025_bib4","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1055\/s-2003-45098","article-title":"Purification of gastroprotective triterpenoids from stem bark of Amphipterygium adstringens; roles of prostaglandins, sulfhydryls, nitric oxide and capsaicin neurons","volume":"69","author":"Arrieta","year":"2003","journal-title":"Planta Medica"},{"key":"10.1016\/j.jep.2014.11.025_bib5","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantization of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Analytical Biochemistry"},{"key":"10.1016\/j.jep.2014.11.025_bib6","article-title":"Mechanisms of esophageal protection, gastroprotection and ulcer healing by melatonin. Implications for the therapeutic use of melatonin in gastroesophageal reflux disease (GERD) and peptic ulcer disease","author":"Brzozowska","year":"2013","journal-title":"Current Pharmaceutical Design"},{"key":"10.1016\/j.jep.2014.11.025_bib7","first-page":"751","article-title":"Involvement of cyclooxygenase (COX)-2 products in acceleration of ulcer healing by gastrin and hepatocyte growth factor","volume":"51","author":"Brzozowski","year":"2000","journal-title":"Journal of Physiology and Pharmacology"},{"key":"10.1016\/j.jep.2014.11.025_bib8","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1124\/jpet.106.105932","article-title":"Prostaglandin\/cyclooxygenase pathway in ghrelin-induced gastroprotection against ischemia-reperfusion injury","volume":"319","author":"Brzozowski","year":"2006","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"10.1016\/j.jep.2014.11.025_bib9","first-page":"485","article-title":"The problem of Helicobacter pylori resistance to antibiotics: a systematic review in Latin America","volume":"109","author":"Camargo","year":"2014","journal-title":"Clinical and Systematic Reviews"},{"key":"10.1016\/j.jep.2014.11.025_bib10","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1093\/abbs\/gms034","article-title":"Ellagic acid facilitates indomethacin-induced gastric ulcer healing via COX-2 up-regulation","volume":"44","author":"Chatterjee","year":"2012","journal-title":"Acta Biochimica et Biophysica Sinica"},{"key":"10.1016\/j.jep.2014.11.025_bib11","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.toxlet.2005.09.026","article-title":"Chemopreventive effect of punicalagin, a novel tannin component isolated from Terminalia catappa, on H-ras-transformed NIH3T3 cells","volume":"163","author":"Chen","year":"2005","journal-title":"Toxicology Letter"},{"key":"10.1016\/j.jep.2014.11.025_bib12","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0304-3835(99)00395-X","article-title":"Folk medicine Terminalia catappa and its major tannin component, punicalagin, are effective against bleomycin-induced genotoxicity in Chinese hamster ovary cells","volume":"152","author":"Chen","year":"2000","journal-title":"Cancer Letter"},{"key":"10.1016\/j.jep.2014.11.025_bib13","doi-asserted-by":"crossref","first-page":"E1142","DOI":"10.1152\/ajpendo.00003.2012","article-title":"Pomegranate juice and punicalagin attenuate oxidative stress and apoptosis in human placenta and in human placental trophoblasts","volume":"302","author":"Chen","year":"2012","journal-title":"American Journal of Physiology and Endocrinology Metabolism"},{"key":"10.1016\/j.jep.2014.11.025_bib14","unstructured":"CLSI Manual Clinical and Laboratory Standards Institute., 2006. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: approved standards. 6\u00aa ed. Performance standards for antimicrobial susceptibility testing. Sixteenth informational supplement M100-S16 (tab 2J). Clinical and Laboratory Standards Institute, Wayne, PA."},{"key":"10.1016\/j.jep.2014.11.025_bib15","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1097\/MOG.0b013e32833f1222","article-title":"Gastroduodenal mucosal defense","volume":"26","author":"De Foneska","year":"2010","journal-title":"Current Opinion Gastroenterology"},{"key":"10.1016\/j.jep.2014.11.025_bib16","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s00210-013-0947-z","article-title":"Geraniol-a flavoring agent with multifunctional effects in protecting the gastric and duodenal mucosa","volume":"387","author":"de Carvalho","year":"2014","journal-title":"Naunyn Schmiedebergs Archieves of Pharmacology"},{"key":"10.1016\/j.jep.2014.11.025_bib17","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1370\/afm.1243","article-title":"Use of acid-suppressive drugs and risk of fracture: a meta-analysis of observational studies","volume":"9","author":"Eom","year":"2011","journal-title":"Annals Family Medicine"},{"key":"10.1016\/j.jep.2014.11.025_bib18","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.fitote.2003.11.007","article-title":"Phytochemical and antiinflammatory studies on Terminalia catappa","volume":"75","author":"Fan","year":"2004","journal-title":"Fitoterapia"},{"key":"10.1016\/j.jep.2014.11.025_bib19","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0378-8741(01)00375-0","article-title":"Ethnobotanical and antimicrobial investigation on some species of Terminalia and Combretum (Combretaceae) growing in Tanzania","volume":"79","author":"Fyhrquist","year":"2002","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2014.11.025_bib20","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/j.cellsig.2007.04.009","article-title":"Oxyl radicals, redox-sensitive signalling cascades and antioxidants","volume":"19","author":"Genestra","year":"2007","journal-title":"Cell Signalling"},{"key":"10.1016\/j.jep.2014.11.025_bib21","series-title":"Farmacopea Vegetal Carbe\u00f1a","first-page":"360","author":"Germos\u00e9n-Robineau","year":"2014"},{"key":"10.1016\/j.jep.2014.11.025_bib22","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.lfs.2013.07.021","article-title":"Roles of pro-angiogenic and anti-angiogenic factors as well as matrix metalloproteinases in healing of NSAID-induced small intestinal ulcers in rats","volume":"93","author":"Gyenge","year":"2013","journal-title":"Life Science"},{"issue":"214\u2013221","key":"10.1016\/j.jep.2014.11.025_bib23","first-page":"2001","article-title":"Less damaging effect of whisky in rat stomachs in comparison with pure ethanol","volume":"64","author":"Iino","year":"2001","journal-title":"Digestion"},{"key":"10.1016\/j.jep.2014.11.025_bib24","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/S0024-3205(01)01493-X","article-title":"Effect of ellagic acid on gastric damage induced in ischemic rat stomachs following ammonia or reperfusion","volume":"70","author":"Iino","year":"2002","journal-title":"Life Science"},{"key":"10.1016\/j.jep.2014.11.025_bib25","first-page":"33","article-title":"Evaluation of the antiulcer activity of pibutidine hydrochloride (IT-066); the new histamine H2-receptor antagonist, in cold-restraint stressand ethanol-induced ulcer models in rats","volume":"31","author":"Khalifa","year":"2002","journal-title":"Al Azhar Medical Journal"},{"key":"10.1016\/j.jep.2014.11.025_bib26","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.phymed.2006.12.012","article-title":"Antioxidant and hepatoprotective actions of medicinal herb, Terminalia catappa L. from Okinawa Island and its tannin corilagin","volume":"14","author":"Kinoshita","year":"2007","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2014.11.025_bib27","first-page":"38","article-title":"Antiulcer activity of ethanolic extract of Terminalia catappa leaves against gastric ulcers by pyrolic ligation induced model in rats","volume":"6","author":"Kumar","year":"2014","journal-title":"International Journal of Pharmaceutical Sciences and Drug Research"},{"key":"10.1016\/j.jep.2014.11.025_bib28","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1053\/j.gastro.2008.05.030","article-title":"Gastric mucosal defense and cytoprotection: bench to bedside","volume":"135","author":"Laine","year":"2008","journal-title":"Gastroenterology"},{"issue":"153\u2013161","key":"10.1016\/j.jep.2014.11.025_bib30","first-page":"1997","article-title":"Evaluation of the antioxidant and hepatoprotective activity of Terminalia catappa","volume":"25","author":"Lin","year":"1997","journal-title":"The American Journal of Chinese Medicine"},{"key":"10.1016\/j.jep.2014.11.025_bib500","doi-asserted-by":"crossref","first-page":"4590","DOI":"10.3748\/wjg.v19.i28.4590","article-title":"Increased expression of matrix metalloproteinase-9 associated with gastric ulcer recurrence","volume":"19","author":"Li","year":"2013","journal-title":"World Journal of Gastroenterology"},{"key":"10.1016\/j.jep.2014.11.025_bib31","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1142\/S0192415X99000422","article-title":"Effects of punicalagin and punicalin on carrageenan-induced inflammation in rats","volume":"27","author":"Lin","year":"1999","journal-title":"The American Journal of Chinese Medicine"},{"key":"10.1016\/j.jep.2014.11.025_bib32","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1021\/jf980864s","article-title":"Evaluation of the antioxidant activity of environmental plants: activity of the leaf extracts from seashore plants","volume":"47","author":"Masuda","year":"1999","journal-title":"Journal of Agriculture Food and Chemistry"},{"key":"10.1016\/j.jep.2014.11.025_bib33","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.fct.2013.07.075","article-title":"Zinc(II)-curcumin accelerates the healing of acetic acid-induced chronic gastric ulcers in rats by decreasing oxidative stress and downregulation of matrix metalloproteinase-9","volume":"60","author":"Mei","year":"2013","journal-title":"Food Chemistry and Toxicology"},{"key":"10.1016\/j.jep.2014.11.025_bib34","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1136\/gutjnl-2012-302254","article-title":"Helicobacter pylori resistance to antibiotics in Europe and its relationship to antibiotic consumption","volume":"62","author":"Megraud","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.jep.2014.11.025_bib35","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/676902","article-title":"Characterization and quantification of compounds in the hydroalcoholic extract of the leaves from Terminalia catappa Linn. (Combretaceae) and their mutagenic activity","author":"Mininel","year":"2014","journal-title":"Evidence-Based Complementary and Alternative Medicine"},{"key":"10.1016\/j.jep.2014.11.025_bib36","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.phymed.2013.01.002","article-title":"Anti-secretory and cyto-protective effects of chebulinic acid isolated from the fruits of Terminalia chebula on gastric ulcers","volume":"20","author":"Mishra","year":"2013","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2014.11.025_bib37","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/S0021-5198(19)39795-1","article-title":"Effects of the new anti-ulcer agent KB-5492 on experimental gastric mucosal lesions and gastric mucosal defensive factors, compared to those of teprenone and cimetidine","volume":"57","author":"Morimoto","year":"1991","journal-title":"Japanese Journal of Pharmacology"},{"key":"10.1016\/j.jep.2014.11.025_bib38","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0378-8741(03)00208-3","article-title":"Antidiabetic activity of Terminalia catappa Linn fruits","volume":"88","author":"Nagappa","year":"2003","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2014.11.025_bib39","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/261745","article-title":"Gastric antiulcerogenic and hypokinetic activities of Terminalia fagifolia Mart. Zucc. (Combretaceae)","author":"Nunes","year":"2014","journal-title":"Biomed Research International"},{"key":"10.1016\/j.jep.2014.11.025_bib40","first-page":"98","article-title":"Antiulcerogenic activity of ethanol extract of the bark from Terminalia catappa in gastric ulcer model induced by ethanol in Rattus norgegicus","volume":"9","author":"Nunes","year":"2012","journal-title":"Pharmacologyonline"},{"key":"10.1016\/j.jep.2014.11.025_bib41","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/BF02235252","article-title":"A method for experimental, penetrating gastric and duodenal ulcers in rats. Observations on normal healing","volume":"16","author":"Okabe","year":"1971","journal-title":"American Journal of Digestive Diseases"},{"key":"10.1016\/j.jep.2014.11.025_bib42","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1248\/bpb.28.1321","article-title":"An overview of acetic acid ulcer models\u2014the history and state of the art of peptic ulcer research","volume":"28","author":"Okabe","year":"2005","journal-title":"Biological and Pharmaceutical Bulletin"},{"key":"10.1016\/j.jep.2014.11.025_bib43","series-title":"Guide to the Care and Use of Experimental Animals","first-page":"1","author":"Olfert","year":"1993"},{"key":"10.1016\/j.jep.2014.11.025_bib44","doi-asserted-by":"crossref","DOI":"10.1186\/1472-6882-10-45","article-title":"Protective effects of a gastrointestinal agent containing Korean red ginseng on gastric ulcer models in mice","author":"Oyagi","year":"2010","journal-title":"BMC Complementary and Alternative Medicine"},{"key":"10.1016\/j.jep.2014.11.025_bib45","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1007\/s00296-013-2709-0","article-title":"Bone density in proton pump inhibitors users: a prospective study","volume":"33","author":"Ozdil","year":"2013","journal-title":"Rheumatology International"},{"key":"10.1016\/j.jep.2014.11.025_bib46","doi-asserted-by":"crossref","first-page":"464","DOI":"10.4103\/0253-7613.117754","article-title":"Antitumor and antioxidant status of Terminalia catappa against Ehrlich ascites carcinoma in Swiss albino mice","volume":"45","author":"Pandya","year":"2013","journal-title":"Indian Journal of Pharmacology"},{"key":"10.1016\/j.jep.2014.11.025_bib47","first-page":"569","article-title":"Sensory nerves and calcitonin gene related peptide in the effect of ischemic preconditioning on acute and chronic gastric lesions induced by ischemia-reperfusion","volume":"52","author":"Pawlik","year":"2001","journal-title":"Journal of Physiology and Pharmacology"},{"key":"10.1016\/j.jep.2014.11.025_bib48","first-page":"1","article-title":"Helicobacter pylori infection: a brief overview on alternative natural treatments to conventional therapy","volume":"10","author":"Parreira","year":"2014","journal-title":"Critical Reviews in Microbiology"},{"key":"10.1016\/j.jep.2014.11.025_bib49","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0378-8741(90)90094-A","article-title":"Evaluation of turmeric (Curcuma longa) for gastric and duodenal antiulcer activity in rats","volume":"29","author":"Rafatullah","year":"1990","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2014.11.025_bib50","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1211\/jpp.59.8.0007","article-title":"Protective effect of (+)-catechin against gastric mucosal injury induced by ischaemia-reperfusion in rats","volume":"59","author":"Rao","year":"2007","journal-title":"Journal of Pharmacy and Pharmacology"},{"key":"10.1016\/j.jep.2014.11.025_bib51","first-page":"213","article-title":"Effects of Terminalia catappa seeds on sexual behaviour and fertility of male rats","volume":"2","author":"Ratnasooriya","year":"2000","journal-title":"Asian Journal of Andrology"},{"key":"10.1016\/j.jep.2014.11.025_bib53","first-page":"43","article-title":"A simple method for the uniform production of gastric ulceration in the rat","volume":"5","author":"Shay","year":"1945","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jep.2014.11.025_bib54","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1007\/BF02088232","article-title":"Gastric injury induced by ethanol and ischemia-reperfusion in the rat. Differing roles for lipid peroxidation and oxygen radicals","volume":"41","author":"Smith","year":"1996","journal-title":"Digestive Diseases and Sciences"},{"key":"10.1016\/j.jep.2014.11.025_bib55","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0065-2423(10)51005-9","article-title":"Prostaglandin EP receptors and their roles in mucosal protection and ulcer healing in the gastrointestinal tract","volume":"51","author":"Takeuchi","year":"2010","journal-title":"Advances Clinical Chemistry"},{"key":"10.1016\/j.jep.2014.11.025_bib56","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.jnutbio.2005.06.008","article-title":"Effective protection of Terminalia catappa L. leaves from damage induced by carbon tetrachloride in liver mitochondria","volume":"17","author":"Tang","year":"2006","journal-title":"Journal of Nutritional Biochemistry"},{"key":"10.1016\/j.jep.2014.11.025_bib57","doi-asserted-by":"crossref","first-page":"4467","DOI":"10.3748\/wjg.v20.i16.4467","article-title":"Increased susceptibility of aging gastric mucosa to injury: the mechanisms and clinical implications","volume":"20","author":"Tarnawski","year":"2014","journal-title":"World Journal of Gastroenterology"},{"key":"10.1016\/j.jep.2014.11.025_bib58","first-page":"8971","article-title":"Natural products and food components with anti-Helicobacter pylori activities","volume":"20","author":"Takeuchi","year":"2014","journal-title":"World Journal of Gastroenterology"},{"key":"10.1016\/j.jep.2014.11.025_bib59","unstructured":"Thomson, L.A.J., Evans, B., 2006. Terminalia catappa (tropical almond), 2.2. In: Elevitch, C.R. (Ed.). Species profiles for pacific Island agroflorestry: permanent agriculture resources (PAR), 2006. \u3008http:\/\/www.traditionaltree.org\u3009."},{"key":"10.1016\/j.jep.2014.11.025_bib501","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3109\/00365528909091124","article-title":"Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats","volume":"162","author":"Ueda","year":"1989","journal-title":"Scandinavian Journal of Gastroenterology"},{"key":"10.1016\/j.jep.2014.11.025_bib60","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.fitote.2010.11.016","article-title":"Synergy research: approaching a new generation of phytopharmaceuticals","volume":"82","author":"Wagner","year":"2011","journal-title":"Fitoterapia"},{"key":"10.1016\/j.jep.2014.11.025_bib61","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1152\/physrev.00004.2008","article-title":"Prostaglandins, NSAIDs, and gastric mucosal protection: why doesn\u05f3t the stomach digest itself?","volume":"88","author":"Wallace","year":"2008","journal-title":"Physiological Review"},{"key":"10.1016\/j.jep.2014.11.025_bib62","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1177\/153537020122601107","article-title":"Inflammatory mediators in gastrointestinal defense and injury","volume":"226","author":"Wallace","year":"2001","journal-title":"Experimental Biology and Medicine"},{"key":"10.1016\/j.jep.2014.11.025_bib63","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.foodchem.2012.10.092","article-title":"Purification, antioxidant activity and protein-precipitating capacity of punicalin from pomegranate husk","volume":"138","author":"Wang","year":"2013","journal-title":"Food Chemistry"},{"key":"10.1016\/j.jep.2014.11.025_bib64","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.jep.2007.09.014","article-title":"Antifungal activity of medicinal plant extracts preliminary screening studies","volume":"115","author":"Webster","year":"2008","journal-title":"Journal of Ethnopharmacology"},{"key":"10.1016\/j.jep.2014.11.025_bib65","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/595292","article-title":"Terminalia catappa exerts antimetastatic effects on hepatocellular carcinoma through transcriptional inhibition of matrix metalloproteinase-9 by modulating NF-\u03baB and AP-1 Activity","author":"Yeh","year":"2012","journal-title":"Evidence-Based Complementary and Alternative Medicine"},{"key":"10.1016\/j.jep.2014.11.025_bib66","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1186\/1472-6882-14-141","article-title":"Terminalia catappa attenuates urokinase-type plasminogen activator expression through Erk pathways in Hepatocellular carcinoma","volume":"14","author":"Yeh","year":"2014","journal-title":"BMC Complementary and Alternative Medicine"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874114008095?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874114008095?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T16:17:31Z","timestamp":1759940251000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874114008095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":66,"alternative-id":["S0378874114008095"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2014.11.025","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Terminalia catappa L.: A medicinal plant from the Caribbean pharmacopeia with anti-Helicobacter pylori and antiulcer action in experimental rodent models","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2014.11.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ireland Ltd.","name":"copyright","label":"Copyright"}]}}