{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:46:02Z","timestamp":1787964362344,"version":"build-2784847793"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,10,15]],"date-time":"2016-10-15T00:00:00Z","timestamp":1476489600000},"content-version":"vor","delay-in-days":319,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"CNPq, CAPES, FAPERJ and PDTIS-FIOCRUZ"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.jep.2015.10.014","type":"journal-article","created":{"date-parts":[[2015,10,21]],"date-time":"2015-10-21T00:39:30Z","timestamp":1445387970000},"page":"490-498","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":71,"special_numbering":"C","title":["Anti-inflammatory effect of Schinus terebinthifolius Raddi hydroalcoholic extract on neutrophil migration in zymosan-induced arthritis"],"prefix":"10.1016","volume":"175","author":[{"given":"Elaine Cruz","family":"Rosas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luana Barbosa","family":"Correa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana de Almeida","family":"P\u00e1dua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thadeu Estevam Moreira Maramaldo","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Luiz Mazzei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan Patrick","family":"Heringer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Alberto","family":"Bizarro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Auxiliadora Coelho","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Raquel","family":"Figueiredo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria G","family":"Henriques","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2015.10.014_bib1","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1002\/art.22023","article-title":"Regulation of interleukin-1beta-induced chemokine production and matrix metalloproteinase 2 activation by epigallocatechin-3-gallate in rheumatoid arthritis synovial fibroblasts","volume":"54","author":"Ahmed","year":"2006","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jep.2015.10.014_bib2","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.4049\/jimmunol.162.3.1685","article-title":"Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10","volume":"162","author":"Ajuebor","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.jep.2015.10.014_bib3","doi-asserted-by":"crossref","first-page":"2648","DOI":"10.1002\/1529-0131(200012)43:12<2648::AID-ANR4>3.0.CO;2-M","article-title":"Combination benefit of treatment with the cytokine inhibitors interleukin-1 receptor antagonist and PEGylated soluble tumor necrosis factor receptor type I in animal models of rheumatoid arthritis","volume":"43","author":"Bendele","year":"2000","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jep.2015.10.014_bib4","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1177\/1535370213520110","article-title":"Blockade of CXCR2 signalling: a potential therapeutic target for preventing neutrophil-mediated inflammatory diseases","volume":"239","author":"Boppana","year":"2014","journal-title":"Exp. Biol. Med."},{"key":"10.1016\/j.jep.2015.10.014_bib5","doi-asserted-by":"crossref","first-page":"3537","DOI":"10.1172\/JCI36389","article-title":"Evidence that cytokines play a role in rheumatoid arthritis","volume":"118","author":"Brennan","year":"2008","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.jep.2015.10.014_bib6","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1055\/s-2004-815483","article-title":"Anti-inflammatory compounds of plant origin. Part II. Modulation of pro-inflammatory cytokines, chemokines and adhesion molecules","volume":"70","author":"Calixto","year":"2004","journal-title":"Planta Med."},{"key":"10.1016\/j.jep.2015.10.014_bib7","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1590\/S0102-695X2010000200001","article-title":"Antiulcer effect of the pepper trees Schinus terebinthifolius Raddi (aroeira-da-praia) and Myracrodruon urundeuva Allem\u00e3o, Anacardiaceae (aroeira-do-sert\u00e3o)","author":"Carlini","year":"2010","journal-title":"Braz. J. Pharmacogn."},{"key":"10.1016\/j.jep.2015.10.014_bib8","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1016\/j.intimp.2008.06.012","article-title":"The anti-allergic activity of the acetate fraction of Schinus terebinthifolius leaves in IgE induced mice paw edema and pleurisy","volume":"8","author":"Cavalher-Machado","year":"2008","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jep.2015.10.014_bib9","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1189\/jlb.1207827","article-title":"Endothelins modulate inflammatory reaction in zymosan-induced arthritis: participation of LTB4, TNF-alpha, and CXCL-1","volume":"84","author":"Conte","year":"2008","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.jep.2015.10.014_bib10","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jep.2005.10.026","article-title":"Anti-bacterial activity of some Brazilian medicinal plants","volume":"105","author":"de Lima","year":"2006","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2015.10.014_bib11","doi-asserted-by":"crossref","first-page":"PL389","DOI":"10.1016\/0024-3205(95)98583-2","article-title":"Zymosan-induced arthritis in rats. II. Effects of anti-inflammatory drugs","volume":"56","author":"Gegout","year":"1995","journal-title":"Life Sci."},{"key":"10.1016\/j.jep.2015.10.014_bib12","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1189\/jlb.0207123","article-title":"Involvement of LTB4 in zymosan-induced joint nociception in mice: participation of neutrophils and PGE2","volume":"83","author":"Guerrero","year":"2008","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.jep.2015.10.014_bib13","doi-asserted-by":"crossref","first-page":"3007","DOI":"10.1182\/blood.V92.9.3007","article-title":"Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing","volume":"92","author":"Hampton","year":"1998","journal-title":"Blood"},{"key":"10.1016\/j.jep.2015.10.014_bib14","first-page":"260","article-title":"Pathogenesis of rheumatoid arthritis: its relevance to therapy in the'\u201890s","volume":"102","author":"Harris","year":"1991","journal-title":"Trans. Am. Clin. Climatol. Assoc."},{"key":"10.1016\/j.jep.2015.10.014_bib15","first-page":"306","article-title":"Arthritogenic actions of recombinant IL-1 and tumour necrosis factor alpha in the rabbit: evidence for synergistic interactions between cytokines in vivo","volume":"75","author":"Henderson","year":"1989","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.jep.2015.10.014_bib16","first-page":"27","article-title":"Expanding role of biologic agents in rheumatoid arthritis","volume":"66","author":"Kalden","year":"2002","journal-title":"J. Rheumatol. Suppl."},{"key":"10.1016\/j.jep.2015.10.014_bib17","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1007\/s12275-009-0097-7","article-title":"Effects of methyl gallate and gallic acid on the production of inflammatory mediators interleukin-6 and interleukin-8 by oral epithelial cells stimulated with Fusobacterium nucleatum","volume":"47","author":"Kang","year":"2009","journal-title":"J Microbiol."},{"key":"10.1016\/j.jep.2015.10.014_bib18","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.coph.2007.03.002","article-title":"Natural products as a gold mine for arthritis treatment","volume":"7","author":"Khanna","year":"2007","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.jep.2015.10.014_bib19","first-page":"1116","article-title":"Targeted therapies for rheumatoid arthritis: a review","author":"Lama","year":"2011","journal-title":"Int. J.\u00a0Pharm. Sci. Res."},{"key":"10.1016\/j.jep.2015.10.014_bib20","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1146\/annurev.med.51.1.207","article-title":"Anti-cytokine therapy for rheumatoid arthritis","volume":"51","author":"Maini","year":"2000","journal-title":"Annu. Rev. Med."},{"key":"10.1016\/j.jep.2015.10.014_bib21","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1056\/NEJMra1004965","article-title":"The pathogenesis of rheumatoid arthritis","volume":"365","author":"McInnes","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jep.2015.10.014_bib22","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1590\/S0102-695X2007000100006","article-title":"Effect of the activity of the brazilian polyherbal formulation: Eucalyptus globulus Labill, Peltodon radicans Pohl and Schinus terebinthifolius Raddi in inflammatory models","author":"Medeiros","year":"2007","journal-title":"Braz. J. Pharmacogn."},{"key":"10.1016\/j.jep.2015.10.014_bib23","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.cell.2010.03.006","article-title":"Inflammation 2010: new adventures of an old flame","volume":"140","author":"Medzhitov","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.jep.2015.10.014_bib24","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s00011-006-5161-8","article-title":"Antiinflammatory effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on zymosan-induced arthritis in mice","volume":"55","author":"Penido","year":"2006","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.jep.2015.10.014_bib25","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.pain.2009.11.006","article-title":"IL-17 mediates articular hypernociception in antigen-induced arthritis in mice","volume":"148","author":"Pinto","year":"2010","journal-title":"Pain"},{"key":"10.1016\/j.jep.2015.10.014_bib26","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1590\/S0100-40422004000500017","article-title":"Valida\u00e7\u00e3o em m\u00e9todos cromatogr\u00e1ficos e eletrofor\u00e9ticos","volume":"27","author":"Ribani","year":"2004","journal-title":"Qu\u00edm. Nova"},{"key":"10.1016\/j.jep.2015.10.014_bib27","doi-asserted-by":"crossref","first-page":"873","DOI":"10.2165\/11633740-000000000-00000","article-title":"Coming to terms with nonsteroidal anti-inflammatory drug gastropathy","volume":"72","author":"Roth","year":"2012","journal-title":"Drugs"},{"key":"10.1016\/j.jep.2015.10.014_bib28","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.jep.2004.10.007","article-title":"Screening of antifungal agents using ethanol precipitation and bioautography of medicinal and food plants","volume":"96","author":"Schmourlo","year":"2005","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2015.10.014_bib29","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1016\/S0140-6736(10)60826-4","article-title":"Rheumatoid arthritis","volume":"376","author":"Scott","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.jep.2015.10.014_bib30","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1179\/096805103125001586","article-title":"Macrophage recognition of zymosan particles","volume":"9","author":"Underhill","year":"2003","journal-title":"J. Endotoxin Res."},{"key":"10.1016\/j.jep.2015.10.014_bib31","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1006\/cyto.1998.0376","article-title":"Generation of inflammatory cytokines in zymosan-induced pleurisy in rats: TNF induces IL-6 and cytokine-induced neutrophil chemoattractant (CINC) in vivo","volume":"10","author":"Utsunomiya","year":"1998","journal-title":"Cytokine"},{"issue":"Suppl. 1","key":"10.1016\/j.jep.2015.10.014_bib32","doi-asserted-by":"crossref","first-page":"SI40","DOI":"10.1136\/ard.58.2008.i40","article-title":"Role of tumour necrosis factor alpha in experimental arthritis: separate activity of interleukin 1beta in chronicity and cartilage destruction","volume":"58","author":"van den Berg","year":"1999","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jep.2015.10.014_bib33","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0367-326X(02)00293-9","article-title":"Antioxidant activity of Paraguayan plant extracts","volume":"74","author":"Vel\u00e1zquez","year":"2003","journal-title":"Fitoterapia"},{"key":"10.1016\/j.jep.2015.10.014_bib34","doi-asserted-by":"crossref","DOI":"10.1038\/nrrheum.2014.80","article-title":"The multifactorial role of neutrophils in rheumatoid arthritis","author":"Wright","year":"2014","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.jep.2015.10.014_bib35","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.jbspin.2012.08.010","article-title":"Gallic acid, a natural polyphenolic acid, induces apoptosis and inhibits proinflammatory gene expressions in rheumatoid arthritis fibroblast-like synoviocytes","volume":"80","author":"Yoon","year":"2013","journal-title":"Jt. Bone Spine"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874115301732?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874115301732?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,15]],"date-time":"2023-08-15T10:44:00Z","timestamp":1692096240000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874115301732"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":35,"alternative-id":["S0378874115301732"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2015.10.014","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anti-inflammatory effect of Schinus terebinthifolius Raddi hydroalcoholic extract on neutrophil migration in zymosan-induced arthritis","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2015.10.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}