{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:43:42Z","timestamp":1786992222463,"version":"build-2736575974"},"reference-count":85,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Brazilian National Council for Scientific and Technological Development"},{"DOI":"10.13039\/501100001689","name":"Academy of Sciences for the Developing World","doi-asserted-by":"publisher","award":["190741\/2015-5"],"award-info":[{"award-number":["190741\/2015-5"]}],"id":[{"id":"10.13039\/501100001689","id-type":"DOI","asserted-by":"publisher"}]},{"name":"University of Maroua","award":["E15\/173-UMa"],"award-info":[{"award-number":["E15\/173-UMa"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.jep.2016.06.004","type":"journal-article","created":{"date-parts":[[2016,6,5]],"date-time":"2016-06-05T15:29:46Z","timestamp":1465140586000},"page":"183-199","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Crateva adansonii DC, an African ethnomedicinal plant, exerts cytotoxicity in vitro and prevents experimental mammary tumorigenesis in vivo"],"prefix":"10.1016","volume":"190","author":[{"given":"St\u00e9phane","family":"Zingue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Cisilotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain Brice","family":"Tueche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anupam","family":"Bishayee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francine Azegha","family":"Mefegue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis Pergaud","family":"Sandjo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal Beatrice","family":"Magne Nde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn","family":"Winter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Michel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek Tantoh","family":"Ndinteh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charline Florence","family":"Awounfack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevine Kamga","family":"Silihe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tito Tresor","family":"Melachio Tanekou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00e2nia Beatriz","family":"Creczynski-Pasa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dieudonn\u00e9","family":"Njamen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2016.06.004_bib1","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S2221-6189(13)60029-3","article-title":"Inhibitory activity of xanthine oxidase by fractions Crateva adansonii","volume":"1","author":"Abdullahi","year":"2012","journal-title":"J. Acute Dis."},{"key":"10.1016\/j.jep.2016.06.004_bib2","first-page":"85","article-title":"Evaluation of the antimicrobial activities of crude extract of Cryptolepis sanguinolenta and Crateva adansonii leaves and their interactions","volume":"1","author":"Agboke","year":"2011","journal-title":"J. Appl. Pharm. Sci."},{"key":"10.1016\/j.jep.2016.06.004_bib3","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0022-1759(94)90396-4","article-title":"A new rapid and simple non-radioactive assay to monitor and determine the proliferation of lymphocytes: an alternative to [3H]thymidine incorporation assay","volume":"170","author":"Ahmed","year":"1994","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.jep.2016.06.004_bib4","first-page":"17","article-title":"Safety evaluation of aqueous extract of Crateva adansonii leaves on selected tissues of rats","volume":"2","author":"Akanji","year":"2013","journal-title":"Fountain J. Nat. Appl. Sci."},{"key":"10.1016\/j.jep.2016.06.004_bib5","unstructured":"Arbonnier, M., 2009. Arbres, arbustes et lianes des zones s\u00e8ches d\u2019Afrique de l\u2019Ouest. Editions Qu\u00e6 RD 10; F- 78026 Versailles Cedex, France; ISBN Qu\u00e6 978-2-7592\u20130313-0; Mus\u00e9um National d\u2019histoire Naturelle (MNHN); Service des publications scientifiques, 57 Rue Cuvier, F- 75005 Paris, France; ISBN MNHN 978-2-85653\u2013626-1, pp. 396\u2013416."},{"key":"10.1016\/j.jep.2016.06.004_bib6","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/mc.20104","article-title":"Mammary glands of sexually immature rats are more susceptible than those of mature rats to the carcinogenic, lethal, and mutagenic effects of N-Nitroso-N-Methylurea","volume":"43","author":"Ariazi","year":"2005","journal-title":"Mol. Carcinog."},{"key":"10.1016\/j.jep.2016.06.004_bib7","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/CEJ.0b013e32834473f4","article-title":"Amla (Emblica officinalis Gaertn), a wonder berry in the treatment and prevention of cancer","volume":"20","author":"Baliga","year":"2011","journal-title":"Eur. J. Cancer Prev."},{"key":"10.1016\/j.jep.2016.06.004_bib8","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1078\/094471103322331458","article-title":"Cytotoxic activity of some lichen extracts on murine and human cancer cell lines","volume":"10","author":"B\u00e9zivin","year":"2003","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2016.06.004_bib9","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1002\/ijc.28108","article-title":"Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer","volume":"133","author":"Bishayee","year":"2013","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.jep.2016.06.004_bib10","doi-asserted-by":"crossref","first-page":"609","DOI":"10.18388\/abp.2005_3421","article-title":"Strategies for overcoming ABC-transporters-mediated multidrug resistance (MDR) of tumor cells","volume":"52","author":"Borowski","year":"2005","journal-title":"Acta Biochim. Pol."},{"key":"10.1016\/j.jep.2016.06.004_bib11","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s00439-008-0529-1","article-title":"Hereditary breast cancer: new genetic developments, new therapeutic avenues","volume":"124","author":"Campeau","year":"2008","journal-title":"Hum. Genet."},{"key":"10.1016\/j.jep.2016.06.004_bib12","series-title":"Crisis of Cancer Impact Worldwide Exposed","author":"Cancer Report Worldwide","year":"2014"},{"key":"10.1016\/j.jep.2016.06.004_bib13","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0003-9861(52)90194-X","article-title":"The mechanism of catalase action 1 \u2013 steady state analysis","volume":"37","author":"Chance","year":"1952","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.jep.2016.06.004_bib14","doi-asserted-by":"crossref","first-page":"7316","DOI":"10.1038\/sj.onc.1206937","article-title":"Hilakiv-Clarke LA. Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling","volume":"22","author":"Clarke","year":"2003","journal-title":"Oncogene"},{"key":"10.1016\/j.jep.2016.06.004_bib15","series-title":"Natural Product Drugs Discovery in Next Millennium","first-page":"8","volume":"39","author":"Cragg","year":"2001"},{"key":"10.1016\/j.jep.2016.06.004_bib16","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0009-9120(01)00263-6","article-title":"The plasma parameter log (Try\/HDL-C) as anatherogenic index: correlation with lipoprotein particle size and esterification rate in apoB-lipoprotein-depleted plasma (FER (HDL)","volume":"34","author":"Dobi\u00e1\u0161ov\u00e1","year":"2001","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.jep.2016.06.004_bib17","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0003-9861(59)90090-6","article-title":"Tissue sulfhydryl group","volume":"82","author":"Ellman","year":"1959","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.jep.2016.06.004_bib18","first-page":"36","article-title":"Phytochemical and anticancer studies on ten medicinal plants used in Nigeria","volume":"4","author":"Falodun","year":"2010","journal-title":"Bayero. J. Pure Appl. Sci."},{"key":"10.1016\/j.jep.2016.06.004_bib19","doi-asserted-by":"crossref","first-page":"2893","DOI":"10.1002\/ijc.25516","article-title":"Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008","volume":"127","author":"Ferlay","year":"2010","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.jep.2016.06.004_bib20","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.biochi.2013.12.008","article-title":"Cytotoxic effects of dillapiole on MDA-MB-231 cells involve the induction of apoptosis through the mitochondrial pathway by inducing an oxidative stress while altering the cytoskeleton network","volume":"99","author":"Ferreira","year":"2014","journal-title":"Biochimie"},{"key":"10.1016\/j.jep.2016.06.004_bib21","first-page":"1951","article-title":"Carcinogenicity of Derivatives of 7,12-Dimethylbenz(a)anthracene","volume":"31","author":"Flesher","year":"1971","journal-title":"Cancer Res."},{"key":"10.1016\/j.jep.2016.06.004_bib22","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1002\/cncr.20978","article-title":"Breast cancer in sub-Saharan Africa: how does it relate to breast cancer in African\u2013American women?","volume":"103","author":"Fregene","year":"2005","journal-title":"Cancer"},{"key":"10.1016\/j.jep.2016.06.004_bib23","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","article-title":"Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge","volume":"18","author":"Friedewald","year":"1972","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jep.2016.06.004_bib24","unstructured":"Galy, 2008. Impacts clinique et economique de l\u2019utilisation de nouvelles mol\u00e9cules de chimiotherapie dans le cancer du sein metastatique: \u00e9tude comparative de 2 cohortes de patientes. Th\u00e8se de doctorat\/PhD no 32\u20132008. Universit\u00e9 De Lyon."},{"key":"10.1016\/j.jep.2016.06.004_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ecam\/neq053","article-title":"Quercetin and Cancer Chemoprevention (Review)","volume":"2011","author":"Gibellini","year":"2011","journal-title":"Evid.\u00a0Complement. Altern. Med."},{"key":"10.1016\/j.jep.2016.06.004_bib26","first-page":"08","article-title":"Ethnomedicinal studies on barks of some medicinal plants in Marathwada (M.S.) India I","volume":"4","author":"Gitte","year":"2012","journal-title":"Recent Res. Sci. Technol."},{"key":"10.1016\/j.jep.2016.06.004_bib27","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/S0021-9258(18)57021-6","article-title":"Determination of serum proteins by the means of biuret reactions","volume":"177","author":"Gonal","year":"1949","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jep.2016.06.004_bib28","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1207\/s15327914nc5302_11","article-title":"Quercetin induces necrosis and apoptosis in SCC-9 oral cancer cells","volume":"53","author":"Haghiac","year":"2005","journal-title":"Nutr. Cancer"},{"key":"10.1016\/j.jep.2016.06.004_bib29","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1023\/B:BREA.0000021048.52430.c0","article-title":"Selective cytotoxicity of a red grape wine flavonoid fraction against MCF-7 cells","volume":"85","author":"Hakimuddin","year":"2004","journal-title":"Breast Cancer Res. Treat."},{"key":"10.1016\/j.jep.2016.06.004_bib30","unstructured":"Halliwell,\u00a0B., Gutteridge, J.M.C., 1997. Free radicals and toxicology. In: Free Radicals in Biology and Medicine. Clarendon Press, Oxford, pp. 1\u201327."},{"key":"10.1016\/j.jep.2016.06.004_bib31","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/1472-6882-8-63","article-title":"Antioxidant and free radical scavenging activity of Spondias pinnata","volume":"8","author":"Hazra","year":"2008","journal-title":"BMC Complement. Alter. Med."},{"key":"10.1016\/j.jep.2016.06.004_bib32","doi-asserted-by":"crossref","first-page":"278","DOI":"10.5012\/bkcs.2012.33.1.278","article-title":"Phenylpropanoids from the roots of codonopsis cordifolioidea and their biological activities","volume":"33","author":"Hu","year":"2012","journal-title":"Bull. Korean Chem. Soc."},{"key":"10.1016\/j.jep.2016.06.004_bib33","first-page":"226","article-title":"Scientific investigation of antitrypanosomal activity of Crateva Adansonii DC leaves extracts. Indo Global","volume":"2","author":"Igoli","year":"2012","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.jep.2016.06.004_bib34","unstructured":"International Agency for Research on Cancer, 2010. Globocan Cameroon Fact Sheets: Breast Cancer. Lyon, France. \u3008http:\/\/globocan.iarc.fr\/\u3009."},{"key":"10.1016\/j.jep.2016.06.004_bib35","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1289\/ehp.11751","article-title":"Oral exposure to Bisphenol A increases dimethylbenzanthracene-induced mammary cancer in rats","volume":"117","author":"Jenkins","year":"2009","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.jep.2016.06.004_bib36","first-page":"341","article-title":"A Cancer Research (UK) randomized Phase II study of idoxifene in patients with locally advanced\/metastatic breast cancer resistant to tamoxifen","volume":"53","author":"Johnston","year":"2003","journal-title":"Cancer Chemother. Pharmcol."},{"key":"10.1016\/j.jep.2016.06.004_bib38","doi-asserted-by":"crossref","first-page":"44","DOI":"10.4236\/abcr.2015.42005","article-title":"Breast cancer survival in Cameroon: analysis of a Cohort of 404 patients at the Yaound\u00e9 General Hospital","volume":"4","author":"Kemfang Ngowa","year":"2015","journal-title":"Adv. Breast Cancer Res."},{"key":"10.1016\/j.jep.2016.06.004_bib39","first-page":"51","article-title":"Antioxidant activity of some common plants","volume":"32","author":"Khalaf","year":"2008","journal-title":"Turk. J. Biol."},{"key":"10.1016\/j.jep.2016.06.004_bib40","doi-asserted-by":"crossref","first-page":"11223","DOI":"10.1021\/ja103756y","article-title":"Conformations, conformational preferences, and conformational exchange of N\u2032-SubstitutedN-Acylguanidines: intermolecular interactions hold the key","volume":"132","author":"Kleinmaier","year":"2010","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jep.2016.06.004_bib41","first-page":"153","article-title":"Innocent A, Kossi K. Activit\u00e9s antioxydantes in vitro des feuilles de Crataeva adansonii","volume":"16","author":"Kplolali","year":"2010","journal-title":"Rev. Ivoir. Sci. Technol."},{"key":"10.1016\/j.jep.2016.06.004_bib42","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1186\/bcr3233","article-title":"Oral low dose and topical tamoxifen for breast cancer prevention: modern approaches for an old drug","volume":"14","author":"Lazzeroni","year":"2012","journal-title":"Breast Cancer Res."},{"key":"10.1016\/j.jep.2016.06.004_bib43","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0278-6915(94)00136-C","article-title":"Comparison of the upand-down, conventional LD50, and fixed-dose acute toxicity procedures","volume":"33","author":"Lipnick","year":"1995","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jep.2016.06.004_bib44","doi-asserted-by":"crossref","first-page":"3434","DOI":"10.2174\/0929867322666150729115321","article-title":"Flavonoids, breast cancer chemopreventive and\/or chemotherapeutic agents","volume":"22","author":"Magne Nde","year":"2015","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.jep.2016.06.004_bib45","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1002\/(SICI)1097-0010(199712)75:4<511::AID-JSFA907>3.0.CO;2-M","article-title":"Nutrient contents, rumen protein degradability and antinutritional factors in some colour and white flowering cultivars of Vicia fababeans","volume":"75","author":"Makkar","year":"1997","journal-title":"J. Sci. Food Agric."},{"key":"10.1016\/j.jep.2016.06.004_bib46","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1749-6632.1997.tb56895.x","article-title":"Results of three life-span experimental carcinogenicity and anticarcinogenicity studies on tamoxifen in rats","volume":"837","author":"Maltoni","year":"1997","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1016\/j.jep.2016.06.004_bib47","series-title":"Molecular Cloning: A Laboratory Manual","author":"Maniatis","year":"1982"},{"key":"10.1016\/j.jep.2016.06.004_bib48","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1002\/ptr.3498","article-title":"Isoflavones as apoptosis inducers in human hepatoma huh-7 cells","volume":"25","author":"Mansoor","year":"2011","journal-title":"Phytother. Res."},{"key":"10.1016\/j.jep.2016.06.004_bib49","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1073\/pnas.68.5.1024","article-title":"An enzyme-based theory of obligate anaerobiosis: the physiological function of superoxide dismutase","volume":"68","author":"Mccord","year":"1976","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.jep.2016.06.004_bib50","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.taap.2008.06.007","article-title":"Estrogen-induced breast cancer: alterations in breast morphology and oxidative stress as a function of estrogen exposure","volume":"232","author":"Mense","year":"2008","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.jep.2016.06.004_bib51","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1080\/01926230701595292","article-title":"Evaluation of organ weights for rodent and non-rodent toxicity studies: a review of regulatory guidelines and a survey of current practices","volume":"35","author":"Michael","year":"2007","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.jep.2016.06.004_bib52","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.ejmhg.2014.05.001","article-title":"Chemopreventive effect of Annona muricata on DMBA-induced cell proliferation in the breast tissues of female albino mice","volume":"15","author":"Minari","year":"2014","journal-title":"Egypt. J. Med. Hum. Genet."},{"key":"10.1016\/j.jep.2016.06.004_bib53","series-title":"Determination of the level of superoxide dismutase in whole blood","first-page":"101","author":"Misra","year":"1972"},{"key":"10.1016\/j.jep.2016.06.004_bib54","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.canlet.2008.03.046","article-title":"Multitargeted cancer prevention by quercetin","volume":"269","author":"Murakami","year":"2008","journal-title":"Cancer Lett."},{"key":"10.1016\/j.jep.2016.06.004_bib55","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1111\/j.1349-7006.2000.tb01030.x","article-title":"Chemoprevention by nimesulide, a selective cyclooxygenase-2 inhibitor, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary gland carcinogenesis in rats","volume":"91","author":"Nakatsugi","year":"2000","journal-title":"Jpn. J. Cancer Res."},{"key":"10.1016\/j.jep.2016.06.004_bib56","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1021\/np200906s","article-title":"Natural products as sources of new drugs over the 30 years from 1981 to 2010","volume":"75","author":"Newman","year":"2012","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.jep.2016.06.004_bib57","first-page":"234","article-title":"Phytochemical screening of Nigerian medical plants (part II)","volume":"41","author":"Odebiyi","year":"1978","journal-title":"Lloydia"},{"key":"10.1016\/j.jep.2016.06.004_bib58","unstructured":"OECD, 2001. OECD Guidelines for Testing of Chemicals: Acute Oral Toxicity-acute Toxic Class Method. Test No. 423, adopted 22nd March 1996, and revised method adopted 17th December 2001.\u00a0OEDC, Paris."},{"key":"10.1016\/j.jep.2016.06.004_bib59","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2015\/751348","article-title":"Advances in the research and development of natural health products as main stream cancer therapeutics","volume":"2015","author":"Ovadje","year":"2015","journal-title":"J. Evid.\u00a0Complement. Alter. Med."},{"key":"10.1016\/j.jep.2016.06.004_bib60","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s11101-014-9337-5","article-title":"Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives","volume":"13","author":"Parikh","year":"2014","journal-title":"Phytochem. Rev."},{"key":"10.1016\/j.jep.2016.06.004_bib61","doi-asserted-by":"crossref","first-page":"5162","DOI":"10.1021\/ol302524q","article-title":"Biomimetic total synthesis of garcibracteatone","volume":"14","author":"Pepper","year":"2012","journal-title":"Org. Lett."},{"key":"10.1016\/j.jep.2016.06.004_bib62","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/ddr.20263","article-title":"New cancer drugs targeting the biosynthesis of estrogens and androgens","volume":"69","author":"Poirier","year":"2008","journal-title":"Drug Dev. Res."},{"key":"10.1016\/j.jep.2016.06.004_bib63","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.canlet.2005.01.014","article-title":"In vitro toxicity evaluation in the development of new anticancer drugs\u2014genistein glycosides","volume":"229","author":"Popio\u0142kiewicz","year":"2005","journal-title":"Cancer Lett."},{"key":"10.1016\/j.jep.2016.06.004_bib64","first-page":"1525","article-title":"Differential sensitivity of human breast cancer cell lines to the growth-inhibitory effects of tamoxifen","volume":"45","author":"Reddel","year":"1985","journal-title":"Cancer Res."},{"key":"10.1016\/j.jep.2016.06.004_bib65","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1002\/mnfr.201100619","article-title":"Modulation of angiogenesis by dietary phytoconstituents in the prevention and intervention of breast cancer","volume":"56","author":"Reuben","year":"2012","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.jep.2016.06.004_bib66","first-page":"244","article-title":"Comparative study of human and rat mammary tumorigenesis","volume":"62","author":"Russo","year":"1990","journal-title":"Lab. Invest"},{"key":"10.1016\/j.jep.2016.06.004_bib67","first-page":"187","article-title":"Comparative study of human and rat mammary tumorigenesis","volume":"5","author":"Russo","year":"2000","journal-title":"Lab. Invest."},{"key":"10.1016\/j.jep.2016.06.004_bib68","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/BF01805718","article-title":"Differentiation of the mammary gland and susceptibility to carcinogenesis","volume":"2","author":"Russo","year":"1982","journal-title":"Breast Cancer Res. Treat."},{"key":"10.1016\/j.jep.2016.06.004_bib69","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.envres.2008.11.005","article-title":"Polycyclic aromatic hydrocarbon-DNA adducts and survival among women with breast cancer","volume":"109","author":"Sagiv","year":"2009","journal-title":"Environ. Res."},{"key":"10.1016\/j.jep.2016.06.004_bib70","first-page":"35","article-title":"Anticancer agents from medicinal plants","volume":"1","author":"Shoeb","year":"2006","journal-title":"Bangladesh J. Pharmacol."},{"key":"10.1016\/j.jep.2016.06.004_bib71","doi-asserted-by":"crossref","first-page":"116","DOI":"10.2174\/1568009615666141229152256","article-title":"Phytochemicals for breast cancer therapy: current status and future implications","volume":"15","author":"Siddiqui","year":"2015","journal-title":"Curr. Cancer Drug Targets"},{"key":"10.1016\/j.jep.2016.06.004_bib72","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0003-2697(72)90132-7","article-title":"Colorimetric assay of catalase","volume":"47","author":"Sinha","year":"1972","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.jep.2016.06.004_bib73","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.2174\/138945012804545632","article-title":"Chemopreventive and chemotherapeutic potential of curcumin in breast cancer","volume":"13","author":"Sinha","year":"2012","journal-title":"Curr. Drug Targets"},{"key":"10.1016\/j.jep.2016.06.004_bib74","doi-asserted-by":"crossref","DOI":"10.1016\/j.semcancer.2015.11.001","article-title":"Resveratrol for breast cancer prevention and therapy: preclinical evidence and molecular mechanisms","author":"Sinha","year":"2016","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/j.jep.2016.06.004_bib75","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/ijc.2910310312","article-title":"Progression of rat mammary development with age and its relationship to carcinogenesis by a chemical carcinogen","volume":"31","author":"Sinha","year":"1983","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.jep.2016.06.004_bib76","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0304-3835(96)04557-0","article-title":"Inhibition of proliferation of estrogen receptor-positive MCF-7 human breast cancer cells by flavono\u00efds in the presence and absence of excess of estrogen","volume":"112","author":"So","year":"1997","journal-title":"Cancer Lett."},{"key":"10.1016\/j.jep.2016.06.004_bib77","unstructured":"Suyatmi, S., Suselo, Y.H., Jusuf, S.A., 2012. The selective cytotoxicity of ethanolic extract of Annona muricata leaf on HeLa cervical cancer cells. In: Proceedings of International Conference: Research and Application on Traditional Complementary and Alternative Medicine in Health Care June, 22nd\u201323rd 2012 Surakarta, Indonesia."},{"key":"10.1016\/j.jep.2016.06.004_bib78","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.jep.2015.02.003","article-title":"Review on ethnomedicinal, phytochemical and pharmacology evidence of Himalayan anticancer plants","volume":"164","author":"Tariq","year":"2015","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.06.004_bib79","first-page":"1106","article-title":"Phytochemical and ethnobotanical study of some selected medicinal plants from Nigeria","volume":"6","author":"Temitope","year":"2010","journal-title":"J. Med. Plants Res."},{"key":"10.1016\/j.jep.2016.06.004_bib80","doi-asserted-by":"crossref","first-page":"224","DOI":"10.5455\/jice.20150430010855","article-title":"Analgesic and free radical scavenging activities of hydromethanolic extract of Crateva adansonii stem bark","volume":"4","author":"Udeh","year":"2015","journal-title":"J. Inter. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.06.004_bib81","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.2174\/187152012803833008","article-title":"Chemoprevention of breast cancer by dietary compounds","volume":"12","author":"Vadodkar","year":"2012","journal-title":"Anticancer Agents Med. Chem."},{"key":"10.1016\/j.jep.2016.06.004_bib82","first-page":"421","article-title":"Morphology of the spleen in adult albino rats after whole-body exposure to low-level of toluene","volume":"2","author":"Voloshin","year":"2014","journal-title":"Int. J. Anat. Res."},{"key":"10.1016\/j.jep.2016.06.004_bib83","first-page":"305","article-title":"Determination of lipid peroxidation","volume":"24","author":"Wilbur","year":"1949","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.jep.2016.06.004_bib84","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s11130-004-0049-7","article-title":"Flavonoids in food and their health bene\ufb01ts","volume":"59","author":"Yao","year":"2004","journal-title":"Plants Foods Hum. Nutr."},{"key":"10.1016\/j.jep.2016.06.004_bib85","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/S0308-8146(98)00102-2","article-title":"The determination of flavonoid contents in mulberry and their scanving effects on superoxide radicals","volume":"64","author":"Zhishen","year":"1999","journal-title":"J. Food Chem."},{"key":"10.1016\/j.jep.2016.06.004_bib86","doi-asserted-by":"crossref","first-page":"253","DOI":"10.6061\/clinics\/2013(02)OA21","article-title":"Effects of the phytoestrogen genistein on the development of the reproductive system of Sprague Dawley rats","volume":"68","author":"Zin","year":"2013","journal-title":"Clinics"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0378874116303567?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0378874116303567?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T23:16:31Z","timestamp":1656630991000},"score":1,"resource":{"primary":{"URL":"http:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874116303567"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":85,"alternative-id":["S0378874116303567"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2016.06.004","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Crateva adansonii DC, an African ethnomedicinal plant, exerts cytotoxicity in vitro and prevents experimental mammary tumorigenesis in vivo","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"http:\/\/dx.doi.org\/10.1016\/j.jep.2016.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}