{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T18:29:07Z","timestamp":1784053747585,"version":"3.55.0"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100007548","name":"Northwest Agriculture and Forestry University","doi-asserted-by":"crossref","award":["Z111021006"],"award-info":[{"award-number":["Z111021006"]}],"id":[{"id":"10.13039\/501100007548","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31571862"],"award-info":[{"award-number":["31571862"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.jep.2016.07.002","type":"journal-article","created":{"date-parts":[[2016,7,3]],"date-time":"2016-07-03T04:54:55Z","timestamp":1467521695000},"page":"256-263","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":64,"special_numbering":"C","title":["Antidiabetic and antihyperlipidemic activities of Forsythia suspensa (Thunb.) Vahl (fruit) in streptozotocin-induced diabetes mice"],"prefix":"10.1016","volume":"192","author":[{"given":"Yanyan","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fu","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongwen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingwu W.","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2016.07.002_bib1","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.etp.2011.09.005","article-title":"Soybean phenolic-rich extracts inhibit keyenzymes linked to type 2 diabetes (\u03b1-amylase and \u03b1-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro","volume":"65","author":"Ademiluyi","year":"2013","journal-title":"Exp. Toxicol. Pathol."},{"key":"10.1016\/j.jep.2016.07.002_bib2","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.jep.2013.11.012","article-title":"Evaluation of antidiabetic and antihyperlipidemic activity of Artemisia indicalinn (aeriel parts) in streptozotocin induced diabetic rats","volume":"151","author":"Ahmad","year":"2014","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.07.002_bib3","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1111\/dom.12540","article-title":"Efficacy and safety of once-weekly dulaglutide in combination with sulphonylurea and\/or biguanide compared with once-daily insulin glargine in Japanese patients with type 2 diabetes: a randomized, open-label, phase III, non-inferiority study","volume":"17","author":"Araki","year":"2015","journal-title":"Diabetes Obes. Metab."},{"key":"10.1016\/j.jep.2016.07.002_bib4","first-page":"109","article-title":"Current trends in herbal medicines","volume":"3","author":"Atmakuri","year":"2010","journal-title":"J. Pharm. Res."},{"key":"10.1016\/j.jep.2016.07.002_bib5","doi-asserted-by":"crossref","first-page":"509","DOI":"10.2147\/DDDT.S75056","article-title":"HMG-CoA reductase inhibitory activity and phytocomponent investigation of Basellaalba leaf extract as a treatment for hypercholesterolemia","volume":"9","author":"Baskaran","year":"2015","journal-title":"Drug Des. Dev. Ther."},{"key":"10.1016\/j.jep.2016.07.002_bib6","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.foodchem.2007.05.077","article-title":"\u03b1-Glucosidase and \u03b1-amylase inhibitory activities of Nepalese medicinal herb Pakhanbhed (Bergenia ciliate, Haw.)","volume":"106","author":"Bhandari","year":"2008","journal-title":"Food Chem."},{"key":"10.1016\/j.jep.2016.07.002_bib7","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/j.bmcl.2010.11.049","article-title":"A novel screening model for the molecular drug for diabetes and obesity based on tyrosine phosphatase Shp2","volume":"21","author":"Bu","year":"2011","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.jep.2016.07.002_bib8","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1097\/01.AOG.0000433006.09219.f1","article-title":"Practice bulletin No. 137: gestational diabetes mellitus","volume":"122","author":"Committee on Practice Bulletins Obstetrics (CPBO)","year":"2013","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.jep.2016.07.002_bib9","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/pca.1194","article-title":"Simultaneous quantification of 14 bioactive constituents in Forsythia suspensa by liquid chroma-tography-electrospray ionization-mass spectrometry","volume":"21","author":"Cui","year":"2010","journal-title":"Phytochem. Anal."},{"key":"10.1016\/j.jep.2016.07.002_bib10","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/S0006-2952(01)00764-X","article-title":"Inhibition of phosphoenolpyruvatecarboxykinase (PEPCK) gene expression by troglitazone: a peroxisome proliferator-activated receptor-\u03b3(PPAR\u03b3)-independent, antioxidant-related mechanism","volume":"62","author":"Davies","year":"2001","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.jep.2016.07.002_bib11","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jep.2014.12.012","article-title":"Assessment of anti-diabetic activity of an ethnopharmacological plant Nerium oleander through alloxan induced diabetes in mice","volume":"161","author":"Dey","year":"2015","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.07.002_bib12","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1159\/000012829","article-title":"Amelioration of alloxan induced diabetes mellitus and oxidative stress in rats by oil of Eruca sativa seeds","volume":"44","author":"El-Missiry","year":"2000","journal-title":"Ann. Nutr. Metab."},{"key":"10.1016\/j.jep.2016.07.002_bib13","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/joim.12330","article-title":"Stratified medicine for the use of antidiabetic medication in treatment of type II diabetes and cancer: where do we go from here?","volume":"277","author":"Emami-Riedmaier","year":"2015","journal-title":"J. Int. Med."},{"issue":"4","key":"10.1016\/j.jep.2016.07.002_bib14","first-page":"443","article-title":"Zinc, antioxidant systems and metallothionein in metal mediated-apoptosis: biochemical and cytochemical aspects","volume":"146","author":"Formigari","year":"2007","journal-title":"Comp. Biochem. Physiol. Part C: Toxicol. Pharmacol."},{"key":"10.1016\/j.jep.2016.07.002_bib15","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.bse.2014.09.012","article-title":"Isolation and characterization of microsatellite markers for Forsythia suspensa (Thunb.) Vahl (Oleaceae) using sequencing technology","volume":"57","author":"Fu","year":"2014","journal-title":"Biochem. Syst. Ecol."},{"issue":"1","key":"10.1016\/j.jep.2016.07.002_bib16","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1021\/acs.jafc.5b04509","article-title":"Polyhydroxytriterpenoids and phenolic constituents from Forsythia suspensa (Thunb.) Vahl leaves","volume":"64","author":"Ge","year":"2016","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jep.2016.07.002_bib17","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/343425a0","article-title":"Regulation of the mevalonate pathway","volume":"343","author":"Goldstein","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.jep.2016.07.002_bib18","doi-asserted-by":"crossref","first-page":"2586","DOI":"10.2337\/diabetes.54.9.2586","article-title":"Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas","volume":"54","author":"Holland","year":"2005","journal-title":"Diabetes"},{"key":"10.1016\/j.jep.2016.07.002_bib19","doi-asserted-by":"crossref","first-page":"12236","DOI":"10.1073\/pnas.192255099","article-title":"Experimental control of pancreatic development and maintenance","volume":"99","author":"Holland","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jep.2016.07.002_bib20","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s13002-015-0019-1","article-title":"Ethnobotanical study on medicinal plants used by Maonan people in","volume":"11","author":"Hong","year":"2015","journal-title":"China J. Ethnobiol. Ethnomed."},{"issue":"5","key":"10.1016\/j.jep.2016.07.002_bib21","first-page":"504","article-title":"Effects of extracts from Forsythia suspense leaves on modulating blood lipids and protecting liver of hyperlipidemic mice","volume":"40","author":"Hou","year":"2010","journal-title":"J. Henan Univ. (Nat. Sci.)"},{"key":"10.1016\/j.jep.2016.07.002_bib22","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.jep.2014.02.042","article-title":"Anti-diabetic effects of the acetone fraction of Sennasingueana stem bark in a type 2 diabetes rat model","volume":"153","author":"Ibrahim","year":"2014","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.07.002_bib23","unstructured":"International Diabetes Federation (IDF), 2011. Diabetes Atlas, 5th Ed. Brussels, Belgium."},{"issue":"7","key":"10.1016\/j.jep.2016.07.002_bib24","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1007\/s00018-013-1388-z","article-title":"\u03b1-Amylase: an enzyme specificity found in various families of glycoside hydrolases","volume":"71","author":"Jane\u010dek","year":"2014","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.jep.2016.07.002_bib25","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.jep.2009.10.038","article-title":"Antidiabetic activity of Paspalumscrobiculatum Linn. in alloxan induced diabetic rats","volume":"127","author":"Jain","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.07.002_bib26","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1002\/ptr.1398","article-title":"Antidiabetic herbal drugs officially approved in China","volume":"17","author":"Jia","year":"2003","journal-title":"Phytother. Res."},{"key":"10.1016\/j.jep.2016.07.002_bib27","doi-asserted-by":"crossref","first-page":"2398","DOI":"10.2337\/diabetes.48.12.2398","article-title":"Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity","volume":"48","author":"Kaneto","year":"1999","journal-title":"Diabetes"},{"key":"10.1016\/j.jep.2016.07.002_bib28","first-page":"1156","article-title":"Alpha-glucosidase inhibitors from leaves of Forsythia suspense in Henan province","volume":"35","author":"Kang","year":"2010","journal-title":"China J. Chin. Mater. Med."},{"key":"10.1016\/j.jep.2016.07.002_bib29","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1038\/nrd1657","article-title":"The evolving role of natural products in drug discovery","volume":"4","author":"Koehn","year":"2005","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.jep.2016.07.002_bib30","first-page":"697","article-title":"A new lignan glycoside from Forsythia suspensa","volume":"12","author":"Li","year":"2014","journal-title":"Chin. J. Nat. Med."},{"issue":"3","key":"10.1016\/j.jep.2016.07.002_bib31","first-page":"385","article-title":"Antioxidant properties in vitro and total phenolic contents in methanol extracts from medicinal plants","volume":"41","author":"Li","year":"2008","journal-title":"Food Sci. Technol."},{"key":"10.1016\/j.jep.2016.07.002_bib32","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1002\/ptr.3260","article-title":"Forsythoside A inhibits the avian infectious bronchitis virus in cell culture","volume":"25","author":"Li","year":"2010","journal-title":"Phytother. Res."},{"key":"10.1016\/j.jep.2016.07.002_bib33","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.jep.2011.02.009","volume":"134","author":"Li","year":"2011","journal-title":"J. Ethnopharmacol."},{"issue":"98\u201399","key":"10.1016\/j.jep.2016.07.002_bib34","first-page":"175","article-title":"Hypoglycemic effect of Forsythia suspensa leaves on diabetic mice","volume":"14","author":"Liu","year":"2013","journal-title":"Agric. Sci. Technol."},{"key":"10.1016\/j.jep.2016.07.002_bib35","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.fct.2013.08.082","article-title":"Antidiabetic activity of mycelia selenium-polysaccharide from Catathelasma ventricosum in STZ-induced diabetic mice","volume":"63","author":"Liu","year":"2013","journal-title":"Food Chem. Toxicol."},{"issue":"3","key":"10.1016\/j.jep.2016.07.002_bib36","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1016\/j.foodchem.2013.04.123","article-title":"The \u03b1-amylase and \u03b1-glucosidase inhibitory effects of Irish seaweed extracts","volume":"141","author":"Lordan","year":"2013","journal-title":"Food Chem."},{"key":"10.1016\/j.jep.2016.07.002_bib37","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s12020-015-0543-8","article-title":"PRMT1 promotes glucose toxicity-induced \u03b2 cell dysfunction by regulating the nucleo-cytoplasmic trafficking of PDX-1 in a FOXO1-dependent manner in INS-1 cells","volume":"49","author":"Lv","year":"2015","journal-title":"Endocrine"},{"key":"10.1016\/j.jep.2016.07.002_bib38","first-page":"51","article-title":"Three new compounds from Forsythia suspensa (Thunb.) Vahl","volume":"9","author":"Ming","year":"1998","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.jep.2016.07.002_bib39","unstructured":"National Institute for Health and Care Excellence (NICE), 2008. Diabetes in pregnancy: management of diabetes and its complications from pre-conception to the postnatal period (Clinical guideline 63). www.nice.org.uk\/guidance\/cg63\/"},{"key":"10.1016\/j.jep.2016.07.002_bib40","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/j.jep.2013.05.044","article-title":"Ethnobotanical study of medicinal plants commonly used by local bedouins in the Badia Region of Jordan","volume":"148","author":"Nawash","year":"2013","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.07.002_bib41","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.2337\/diabetes.52.7.1732","article-title":"PDX-1 protein containing its own antennapedia-like protein transduction domain can transduce pancreatic duct and islet cells","volume":"52","author":"Noguchi","year":"2003","journal-title":"Diabetes"},{"key":"10.1016\/j.jep.2016.07.002_bib42","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.bbrc.2015.09.065","article-title":"Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: a model for statin-induced myopathy","volume":"466","author":"Osaki","year":"2015","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jep.2016.07.002_bib43","first-page":"1069","article-title":"Antidiabetic activity of Thespesia populnea bark and leaf extract against streptozotocin induced diabetic rats","volume":"1","author":"Parthasarathy","year":"2009","journal-title":"Int. J. Pharmtechnol. Res."},{"issue":"6","key":"10.1016\/j.jep.2016.07.002_bib44","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1016\/j.bmcl.2008.01.115","article-title":"Lignans from the fruits of Forsythia suspensa","volume":"18","author":"Piao","year":"2008","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.jep.2016.07.002_bib45","first-page":"739834","article-title":"Inhibitory potential of five traditionally used native antidiabetic medicinal plants on \u03b1-amylase, \u03b1-glucosidase, glucose entrapment, and amylolysis kinetics in vitro","author":"Picot","year":"2014","journal-title":"Adv. Pharmacol. Sci."},{"key":"10.1016\/j.jep.2016.07.002_bib46","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.bioorg.2011.09.005","article-title":"Isoforsythiaside, an antioxidant and antibacterial phenylethanoid glycoside isolated from Forsythia suspense","volume":"40","author":"Qu","year":"2012","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.jep.2016.07.002_bib47","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S1521-690X(03)00031-9","article-title":"Hepatic glucose metabolism in humans-its role in health and disease","volume":"17","author":"Roden","year":"2003","journal-title":"Best. Pract. Res. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jep.2016.07.002_bib48","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/S0031-9422(01)00028-0","article-title":"Dammarane derivatives from the dried fruits of Forsythia suspense","volume":"56","author":"Rouf","year":"2001","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jep.2016.07.002_bib49","doi-asserted-by":"crossref","first-page":"4214","DOI":"10.1128\/AAC.00617-06","article-title":"Glibenclamide, a blocker of K+ATP channels, shows antileishmanial activity in experimental murine cutaneous leishmaniasis","volume":"50","author":"Serrano-Mart\u00edn","year":"2006","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jep.2016.07.002_bib50","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.jep.2009.10.013","article-title":"Anti-diabetic potential of alkaloid rich fraction from Capparis decidua on diabetic mice","volume":"127","author":"Sharma","year":"2010","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.jep.2016.07.002_bib51","first-page":"1","article-title":"Potent \u03b1-amylase inhibitory activity of Indian Ayurvedic medicinal plants","volume":"11","author":"Sudha","year":"2011","journal-title":"BMC Complement Altern. Med."},{"key":"10.1016\/j.jep.2016.07.002_bib52","first-page":"537","article-title":"The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas","volume":"50","author":"Szkudelski","year":"2001","journal-title":"Physiol. Res."},{"key":"10.1016\/j.jep.2016.07.002_bib53","doi-asserted-by":"crossref","unstructured":"Tanaka, Y., Gleason, C.E., Tran, P.O., Harmon, J.S., Robertson, R.P., 1999. Prevention of Glucose toxicity in HIT-T15 Cells and Zucker Diabetic Fatty Rats by Antioxidants. In: Proceedings of the National Academy of Sciences of the United States of America. 96, pp. 10857\u201310862.","DOI":"10.1073\/pnas.96.19.10857"},{"key":"10.1016\/j.jep.2016.07.002_bib54","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1016\/j.jep.2011.08.059","article-title":"Hypoglycaemic activity and molecular mechanisms of Caesalpiniaferrea Martius bark extract on streptozotocin-induced diabetes in Wistar rats","volume":"137","author":"Vasconcelos","year":"2011","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.07.002_bib55","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.mce.2009.03.001","article-title":"Astragalus polysaccharides decreased the expression of PTP1B through relieving ER stress induced activation of ATF6 in a rat model of type 2 diabetes","volume":"307","author":"Wang","year":"2009","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.jep.2016.07.002_bib56","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.2337\/diab.45.11.1478","article-title":"The human glucokinase gene \u03b2 cell-type promoter: an essential role of insulin promoter factor 1 (IPF1)\/PDX-1 in its activation in HIT-T15 cells","volume":"45","author":"Watada","year":"1996","journal-title":"Diabetes"},{"issue":"3","key":"10.1016\/j.jep.2016.07.002_bib57","first-page":"643","article-title":"Diabetes mellitus and free radical: free radicals, transition metals and oxidative stress in the aetiology of diabetes mellitus and complications","volume":"49","author":"Wolff","year":"1993","journal-title":"Br. Med. Bull."},{"key":"10.1016\/j.jep.2016.07.002_bib58","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.carbpol.2008.08.003","article-title":"Protective effect of sulfated Achyranthesbidentata polysaccharides on streptozotocin-induced oxidative stress in rats","volume":"75","author":"Xue","year":"2009","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.jep.2016.07.002_bib59","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.jep.2013.11.021","article-title":"Evaluation of hypoglycemic activity of total lignans from FructusArctii in the spontaneously diabetic Goto-Kakizaki rats","volume":"151","author":"Xu","year":"2014","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.07.002_bib60","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.jep.2011.02.020","article-title":"Beneficial effect of the leaves of Murrayakoenigii (Linn.) Spreng (Rutaceae) on diabetes-induced renal damage in vivo","volume":"135","author":"Yankuzo","year":"2011","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.07.002_bib61","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.foodchem.2009.03.073","article-title":"Protective effect of selenium-polysaccharides from the mycelia of Coprinuscomatus on alloxan-induced oxidative stress in mice","volume":"117","author":"Yu","year":"2009","journal-title":"Food Chem."},{"key":"10.1016\/j.jep.2016.07.002_bib62","doi-asserted-by":"crossref","DOI":"10.3382\/ps.2013-03772","article-title":"Forsythia suspensa extract attenuates corticosterone-induced growth inhibition, oxidative injury, and immune depression in broilers","author":"Zeng","year":"2014","journal-title":"Poult. Sci."},{"key":"10.1016\/j.jep.2016.07.002_bib63","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.biopha.2007.07.006","article-title":"Hepatic glucokinase activity is the primary defect in alloxan-induced diabetes of mice","volume":"63","author":"Zhang","year":"2009","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2016.07.002_bib64","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.intimp.2014.06.039","article-title":"Anti-diabetic effect of mulberry leaf polysaccharide by inhibiting pancreatic islet cell apoptosis and ameliorating insulin secretory capacity in diabetic rats","volume":"22","author":"Zhang","year":"2014","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jep.2016.07.002_bib65","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.phymed.2011.01.001","article-title":"Antidiabetic effect of a newly identified component of Opuntia dillenii polysaccharides","volume":"18","author":"Zhao","year":"2011","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2016.07.002_bib66","doi-asserted-by":"crossref","first-page":"871","DOI":"10.3892\/mmr.2014.2874","article-title":"Ethanol extract of Forsythia suspensa root induces apoptosis of esophageal carcinoma cells via the mitochondrial apoptotic pathway","volume":"11","author":"Zhao","year":"2015","journal-title":"Mol. Med. Rep."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116304251?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116304251?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T03:49:53Z","timestamp":1600832993000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874116304251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":66,"alternative-id":["S0378874116304251"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2016.07.002","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antidiabetic and antihyperlipidemic activities of Forsythia suspensa (Thunb.) Vahl (fruit) in streptozotocin-induced diabetes mice","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2016.07.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}