{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T08:30:57Z","timestamp":1782549057961,"version":"3.54.5"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.jep.2016.07.042","type":"journal-article","created":{"date-parts":[[2016,7,17]],"date-time":"2016-07-17T07:25:07Z","timestamp":1468740307000},"page":"183-191","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"special_numbering":"C","title":["Curative effect of Amorphophallus paeoniifolius tuber on experimental hemorrhoids in rats"],"prefix":"10.1016","volume":"192","author":[{"given":"Yadu Nandan","family":"Dey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manish M.","family":"Wanjari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dharmendra","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinay","family":"Lomash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankush D.","family":"Jadhav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2016.07.042_bib2","series-title":"The Ayurvedic Formulary of India","author":"Anonymous","year":"2000"},{"key":"10.1016\/j.jep.2016.07.042_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/530931","article-title":"An improved experimental model of hemorrhoids in rats: evaluation of antihemorrhoidal activity of an herbal formulation","volume":"530931","author":"Azeemuddin","year":"2014","journal-title":"ISRN Pharmacology"},{"key":"10.1016\/j.jep.2016.07.042_bib6","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4103\/0973-8258.116387","article-title":"Protective effect of Amorphophallus campanulatus tuber extracts against H2O2 induced oxidative damage in human erythrocytes and leucocytes","volume":"7","author":"Bais","year":"2013","journal-title":"Int. J. Green. Pharm."},{"key":"10.1016\/j.jep.2016.07.042_bib7","first-page":"691","article-title":"Glucomannan in prevention of oxidative stress and inflammation occurring in adjuvant arthritis","volume":"29","author":"Bauerova","year":"2008","journal-title":"Neuro. Endocrinol. Lett."},{"key":"10.1016\/j.jep.2016.07.042_bib8","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/1523-1747.ep12506462","article-title":"Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker","volume":"78","author":"Bradley","year":"1982","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jep.2016.07.042_bib9","first-page":"S1","article-title":"Minimally invasive procedures: what family physicians need to know","volume":"54","author":"Brill","year":"2005","journal-title":"J. Fam. Pract."},{"key":"10.1016\/j.jep.2016.07.042_bib10","doi-asserted-by":"crossref","first-page":"12","DOI":"10.2741\/A171","article-title":"Cytokines in acute and chronic inflammation","volume":"2","author":"Carol","year":"1997","journal-title":"Front. Biosci."},{"key":"10.1016\/j.jep.2016.07.042_bib11","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.1016\/j.carbpol.2011.10.053","article-title":"Methodologies for the extraction and analysis of konjac glucomannan from corms of Amorphophallus konjac K. Koch","volume":"87","author":"Chua","year":"2012","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.jep.2016.07.042_bib12","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1016\/j.carres.2009.09.025","article-title":"Isolation and characterization of a heteropolysaccharide from the corm of Amorphophallus campanulatus","volume":"344","author":"Das","year":"2009","journal-title":"Carbohydr. Res."},{"key":"10.1016\/j.jep.2016.07.042_bib13","doi-asserted-by":"crossref","first-page":"651","DOI":"10.4103\/0250-474X.59547","article-title":"Effects of petroleum ether extract of Amorphophallus paeoniifolius tuber on central nervous system in mice","volume":"71","author":"Das","year":"2009","journal-title":"Indian J. Pharm. Sci."},{"key":"10.1016\/j.jep.2016.07.042_bib14","first-page":"1","article-title":"Anti-inflammatory activity of methanolic extract of Amorphophallus paeoniifolius and its possible mechanism","volume":"1","author":"De","year":"2010","journal-title":"Int. J. Pharma Bio. Sci."},{"key":"10.1016\/j.jep.2016.07.042_bib15","first-page":"171","article-title":"Plants used by the tribes for the treatment of digestive system disorders in Wayanad district, Kerala","volume":"3","author":"Devi Prasad","year":"2013","journal-title":"J. Appl. Pharm. Sci."},{"key":"10.1016\/j.jep.2016.07.042_bib16","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4103\/0974-8520.100303","article-title":"A phytopharmacological review on an important medicinal plant - Amorphophallus paeoniifolius","volume":"33","author":"Dey","year":"2012","journal-title":"AYU"},{"key":"10.1016\/j.jep.2016.07.042_bib17","doi-asserted-by":"crossref","first-page":"36","DOI":"10.5455\/jice.20151211063819","article-title":"Gastrokinetic activity of Amorphophallus paeoniifolius tuber in rats","volume":"5","author":"Dey","year":"2016","journal-title":"J. Intercult. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.07.042_bib18","doi-asserted-by":"crossref","first-page":"253","DOI":"10.4077\/CJP.2013.BAB127","article-title":"Herbal haemorrhoidal cream for haemorrhoids","volume":"56","author":"Gurel","year":"2013","journal-title":"Chin. J. Physiol."},{"key":"10.1016\/j.jep.2016.07.042_bib19","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0041-008X(85)90098-5","article-title":"Effects of cadmium on glutathione peroxidase, superoxide dismutase and lipid peroxidation in the rat heart: a possible mechanism of cadmium cardiotoxicity","volume":"80","author":"Jamal","year":"1985","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.jep.2016.07.042_bib20","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jamcollsurg.2006.08.022","article-title":"Hemorrhoidal disease: a comprehensive review","volume":"204","author":"Kaidar-Person","year":"2007","journal-title":"J. Am. Coll. Surg."},{"key":"10.1016\/j.jep.2016.07.042_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1746-4269-1-11","article-title":"Ethnomedicinal botany of the Apatani in the Eastern Himalayan region of India","volume":"1","author":"Kala","year":"2005","journal-title":"J. Ethnobiol. Ethnomed."},{"key":"10.1016\/j.jep.2016.07.042_bib23","series-title":"Practical Pharmacognosy","author":"Khandelwal","year":"2006"},{"key":"10.1016\/j.jep.2016.07.042_bib24","volume":"45","author":"Khare","year":"2007"},{"key":"10.1016\/j.jep.2016.07.042_bib25","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/0016-5085(84)90202-6","article-title":"Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity assessment of inflammation in rat and hamster models","volume":"87","author":"Krawisz","year":"1984","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jep.2016.07.042_bib26","first-page":"446","volume":"9","author":"Lim","year":"2015"},{"key":"10.1016\/j.jep.2016.07.042_bib27","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.carbpol.2015.05.025","article-title":"Preparation, composition analysis and antioxidant activities of konjac oligo-glucomannan","volume":"130","author":"Liu","year":"2015","journal-title":"Carbohydr. Polym"},{"key":"10.1016\/j.jep.2016.07.042_bib28","first-page":"255","article-title":"Total phenolics and flavonoids in Bulgarian fruits and vegetables","volume":"40","author":"Marinova","year":"2005","journal-title":"J. Univ. Chem. Tech. Metall."},{"key":"10.1016\/j.jep.2016.07.042_bib29","series-title":"Indian Medicinal Plants","first-page":"118","volume":"3","author":"Nair","year":"1993"},{"key":"10.1016\/j.jep.2016.07.042_bib30","first-page":"1063","article-title":"In vitro quantification of flavonoids and phenolic content of \u2013 Suran","volume":"1","author":"Nataraj","year":"2009","journal-title":"Int. J. Chem. Tech. Res"},{"key":"10.1016\/j.jep.2016.07.042_bib31","doi-asserted-by":"crossref","first-page":"67","DOI":"10.5530\/rjps.2012.1.9","article-title":"Evaluation of gastroprotective ability of Amorphophallus paeoniifolius corms against indomethacin induced gastric ulcers","volume":"2","author":"Nataraj","year":"2012","journal-title":"RGUHS J. Pharm. Sci."},{"key":"10.1016\/j.jep.2016.07.042_bib101","first-page":"155","article-title":"Characterization of polysaccharide from Amorphophallus paeoniifolius in Vietnam","volume":"47","author":"Nguyen","year":"2009","journal-title":"J. Chem."},{"key":"10.1016\/j.jep.2016.07.042_bib32","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1254\/fpj.92.215","article-title":"Croton oil-induced hemorrhoid model in rat: comparison of anti-inflammatory activity of diflucortolone valerate with other glucocorticoids","volume":"92","author":"Nishiki","year":"1988","journal-title":"Nihon Yakurigaku Zasshi"},{"key":"10.1016\/j.jep.2016.07.042_bib33","first-page":"87","article-title":"Blood sample collection in small laboratory animals","volume":"1","author":"Parasuraman","year":"2010","journal-title":"J. Pharmacol. Pharm."},{"key":"10.1016\/j.jep.2016.07.042_bib34","doi-asserted-by":"crossref","first-page":"52","DOI":"10.12991\/201317393","article-title":"The effect of betulinic acid on TNBS-induced experimental colitis","volume":"17","author":"Sener","year":"2013","journal-title":"Marmara Pharm. J."},{"key":"10.1016\/j.jep.2016.07.042_bib35","first-page":"429","article-title":"Isolation and characterization of secondary metabolite from Amorphophallus paeoniifolius for hepatoprotective activity","volume":"1","author":"Sharstry","year":"2010","journal-title":"Res. J. Pharm. Bio. Chem. Sci."},{"key":"10.1016\/j.jep.2016.07.042_bib36","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.fitote.2005.03.024","article-title":"Analgesic activity of Amorphophallus paeoniifolius tuber","volume":"76","author":"Shilpi","year":"2005","journal-title":"Fitoterpia"},{"key":"10.1016\/j.jep.2016.07.042_bib37","first-page":"152","article-title":"Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent","volume":"299","author":"Singleton","year":"1999"},{"key":"10.1016\/j.jep.2016.07.042_bib38","doi-asserted-by":"crossref","first-page":"144","DOI":"10.5344\/ajev.1965.16.3.144","article-title":"Colorimetry of total phenolics with phosphomolybdic- phosphotungstic acid reagents","volume":"16","author":"Singleton","year":"1965","journal-title":"Am. J. Enol. Vitic."},{"key":"10.1016\/j.jep.2016.07.042_bib39","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2478\/intox-2013-0002","article-title":"Efficacy of quercetin derivatives in prevention of ulcerative colitis in rats","volume":"6","author":"Sotnikova","year":"2013","journal-title":"Interdiscip. Toxicol."},{"key":"10.1016\/j.jep.2016.07.042_bib40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4172\/2155-9600.1000274","article-title":"Phytochemical and nutritional evaluation of Amorphophallus campanulatus (Roxb.) Blume Corm","volume":"4","author":"Srivastava","year":"2014","journal-title":"J. Nutr. Food Sci."},{"key":"10.1016\/j.jep.2016.07.042_bib41","first-page":"502","article-title":"Ethnobotanical study of medicinal plants used by Malayali Tribals in Kollihills of Tamilnadu, India","volume":"2","author":"Suresh","year":"2011","journal-title":"Int. J. Res. Ayurveda Pharm."},{"key":"10.1016\/j.jep.2016.07.042_bib42","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.bcdf.2013.09.005","article-title":"Tolerance and nutritional therapy of dietary fibre from konjac glucomannan hydrolysates for patients with inflammatory bowel disease (IBD)","volume":"2","author":"Suwannaporna","year":"2013","journal-title":"Bioact. Carbohydr. Diet. Fibre"},{"key":"10.1016\/j.jep.2016.07.042_bib43","series-title":"Quality standards of Indian medicinal plants","first-page":"39","volume":"11","author":"Tandon","year":"2013"},{"key":"10.1016\/j.jep.2016.07.042_bib44","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.ejphar.2010.12.012","article-title":"Protective effect of embelin against acetic acid induced ulcerative colitis in rats","volume":"654","author":"Thippeswamy","year":"2011","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jep.2016.07.042_bib45","first-page":"74","article-title":"Wild edible plants traditionally used by the tribes in the Parambikulam Wildlife Sanctuary, Kerala, India","volume":"6","author":"Yesodharan","year":"2007","journal-title":"Nat. Prod. Rad."},{"key":"10.1016\/j.jep.2016.07.042_bib46","first-page":"322","article-title":"Status of ethnomedicinal plants in the Parambikulam Wildlife sanctuary, Kerala","volume":"15","author":"Yesodharan","year":"2007","journal-title":"South India Ann."},{"key":"10.1016\/j.jep.2016.07.042_bib47","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.bbrc.2009.11.009","article-title":"Protective role of betulinic acid on TNF-alpha-induced cell adhesion molecules in vascular endothelial cells","volume":"391","author":"Yoon","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116304640?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116304640?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T07:08:00Z","timestamp":1692428880000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874116304640"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":44,"alternative-id":["S0378874116304640"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2016.07.042","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Curative effect of Amorphophallus paeoniifolius tuber on experimental hemorrhoids in rats","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2016.07.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}