{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T17:55:55Z","timestamp":1781286955133,"version":"3.54.1"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31302136"],"award-info":[{"award-number":["31302136"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Special Fund of the Chinese Central Government for Basic Scientific Research Operations in Commonwealth Research Institutes","award":["1610322014011"],"award-info":[{"award-number":["1610322014011"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.jep.2016.07.057","type":"journal-article","created":{"date-parts":[[2016,7,23]],"date-time":"2016-07-23T05:25:10Z","timestamp":1469251510000},"page":"350-361","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"special_numbering":"C","title":["Microwave-assisted extraction of three bioactive alkaloids from Peganum harmala L. and their acaricidal activity against Psoroptes cuniculi in vitro"],"prefix":"10.1016","volume":"192","author":[{"given":"Xiaofei","family":"Shang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hu","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolou","family":"Miao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2016.07.057_bib1","first-page":"93","article-title":"Study on medicinal utilization method of Peganum harmala L. by Kazak, Uigur and Mongolian in xingjiang","volume":"20","author":"Baolidebate","year":"2011","journal-title":"J. MUC"},{"key":"10.1016\/j.jep.2016.07.057_bib2","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/pca.973","article-title":"Microwave-assisted extraction of the main phenolic compounds in flax seed","volume":"18","author":"Beejmohun","year":"2007","journal-title":"Phytochem. Anal."},{"key":"10.1016\/j.jep.2016.07.057_bib3","series-title":"The Moroccan Pharmacopoeia of Traditional Arab Medicine and Ancient Folklore","first-page":"529","author":"Bellakhdar","year":"1997"},{"key":"10.1016\/j.jep.2016.07.057_bib4","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.jep.2009.04.035","article-title":"Assessing medicinal plants from south-eastern Spain for potential anti-inflammatory effects targeting nuclear factor-KappaB and other pro-inflammatory mediators","volume":"124","author":"Bremner","year":"2009","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.07.057_bib5","doi-asserted-by":"crossref","first-page":"6213","DOI":"10.1016\/j.chroma.2011.07.040","article-title":"Microwave-assisted extractions of active ingredients from plants","volume":"1218","author":"Chan","year":"2011","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jep.2016.07.057_bib6","doi-asserted-by":"crossref","unstructured":"Chemat, F., Cravotto, G., 2013. Microwave-assisted extraction for bioactive compounds: theory and practice, in: Springer, N.Y. (Ed.) Food Engineering Series, pp. 4.","DOI":"10.1007\/978-1-4614-4830-3"},{"key":"10.1016\/j.jep.2016.07.057_bib7","first-page":"443","article-title":"Determination of harmine and hamaline in seeds of Paganum harmal Genus by HPLC with fluorescence detection","volume":"39","author":"Cheng","year":"2008","journal-title":"Chin. J. Pharm."},{"key":"10.1016\/j.jep.2016.07.057_bib8","series-title":"Drug Standards of the Ministry of Public Health of the People's Republic of China (Uygur Pharmaceutical Section)","author":"Chinese Pharmacopoeia Committee","year":"1998"},{"key":"10.1016\/j.jep.2016.07.057_bib9","series-title":"Flora Reipublicae Popularis Sinicas","author":"Commission of Flora Reipublicae Popularis Sinicas","year":"2004"},{"key":"10.1016\/j.jep.2016.07.057_bib10","doi-asserted-by":"crossref","first-page":"8212","DOI":"10.1086\/421776","article-title":"First documentation of in vivo and in vitro ivermectin resistance in Sarcoptes scabiei","volume":"39","author":"Currie","year":"2004","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.jep.2016.07.057_bib11","doi-asserted-by":"crossref","first-page":"512","DOI":"10.7589\/0090-3558-43.3.512","article-title":"Fatal Sarcoptes scabiei infection of blue sheep (Pseudois nayaur) in Pakistan","volume":"43","author":"Dagleish","year":"2007","journal-title":"J. Wildl. Dis."},{"key":"10.1016\/j.jep.2016.07.057_bib12","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0021-9673(00)00921-3","article-title":"Analytical-scale microwave-assisted extraction","volume":"902","author":"Eskilsson","year":"2000","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jep.2016.07.057_bib13","doi-asserted-by":"crossref","first-page":"7846","DOI":"10.3390\/ijms12117846","article-title":"Rapid and green analytical method for the determination of quinoline alkaloids from Cinchona succirubra based on microwave-integrated extraction and leaching (MIEL) prior to high performance liquid chromatography","volume":"12","author":"Fabiano-Tixier","year":"2011","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2016.07.057_bib14","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.jep.2007.10.014","article-title":"Evaluation of the analgesic effect of alkaloid extract of Peganum harmala L. possible mechanisms involved","volume":"115","author":"Farouk","year":"2008","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.07.057_bib15","first-page":"129","article-title":"Efficient in vitro multiplication of Syrian Rue (Peganum harmala L.) using 6-benzylaminopurine pre-conditioned seedling explants","volume":"7","author":"Goel","year":"2009","journal-title":"Nat. Sci."},{"key":"10.1016\/j.jep.2016.07.057_bib16","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0304-4017(93)90149-H","article-title":"Environmental effects of the usage of avermectines in livestock","volume":"48","author":"Halley","year":"1993","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.jep.2016.07.057_bib17","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1016\/j.bmcl.2009.03.039","article-title":"Peganine hydrochloride dihydrate an orally active antileishmanial agent","volume":"19","author":"Khaliq","year":"2009","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.jep.2016.07.057_bib18","first-page":"110","article-title":"Preliminary study on ultrasonic extraction of total alkaloids from seeds of Peganum harmala L","volume":"14","author":"Li","year":"2005","journal-title":"Acta Agric. Boreal.-Occident. Sin."},{"key":"10.1016\/j.jep.2016.07.057_bib19","first-page":"52","article-title":"Optimum extracting conditions of total alkaloid from Peganum harmala based on response surface design","volume":"33","author":"Liao","year":"2014","journal-title":"China Brew."},{"key":"10.1016\/j.jep.2016.07.057_bib20","first-page":"420","article-title":"Quality standard for alkaloid extract of Paganum harmal L","volume":"41","author":"Liu","year":"2010","journal-title":"Chin. J. Pharm."},{"key":"10.1016\/j.jep.2016.07.057_bib21","first-page":"65","article-title":"Study on the microwave-assisted extraction of the total steroidal alkaloids from Solanum nigrum L","volume":"17","author":"Liu","year":"2005","journal-title":"Nat. Prod. Res. Dev."},{"key":"10.1016\/j.jep.2016.07.057_bib22","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.0269-283X.2004.00488.x","article-title":"Acaricidal activity of aqueous extracts of chamomile flowers, Matricaria chamomilla, against the mite Psoroptes cuniculi","volume":"18","author":"Macchioni","year":"2004","journal-title":"Med. Vet. Entomol."},{"key":"10.1016\/j.jep.2016.07.057_bib23","first-page":"365","article-title":"Antileishmanial activity of Peganum harmala extract on the in vitro Growth Of Leishmania majorpromastigotes in comparison to a trivalent antimony drug","volume":"77","author":"Mirzaie","year":"2007","journal-title":"Vet. Arh."},{"key":"10.1016\/j.jep.2016.07.057_bib24","first-page":"65","article-title":"Antinociceptive effects of Peganum harmala L. alkaloid extract on mouse formalin test","volume":"7","author":"Monsef","year":"2004","journal-title":"J. Pharm. Pharm. Sci."},{"key":"10.1016\/j.jep.2016.07.057_bib25","first-page":"20","article-title":"Introduction the Uygur nationality traditional medicine- Peganum harmala L","volume":"4","author":"Mu","year":"2004","journal-title":"Zhongguo Minzu Yiyu Zazhi"},{"key":"10.1016\/j.jep.2016.07.057_bib26","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.fitote.2010.04.004","article-title":"Antibacterial and antifungal activities of (beta)-carboline alkaloids of Peganum harmala (L) Seeds and Their Combination effects","volume":"81","author":"Nenaah","year":"2010","journal-title":"Fitoter"},{"key":"10.1016\/j.jep.2016.07.057_bib27","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.vetpar.2011.12.015","article-title":"Acaricidal activity of extract from Eupatorium adenophorum against the Psoroptes cuniculi and Sarcoptes scabiei in vitro","volume":"187","author":"Nong","year":"2012","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.jep.2016.07.057_bib28","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0304-4017(99)00056-4","article-title":"Treatment of psoroptic mange with reference to epidemiology and history","volume":"83","author":"O\u2019Brien","year":"1999","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.jep.2016.07.057_bib29","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1002\/pca.1117","article-title":"Microwave-assisted extraction of glucosinolates from Eruca sativa sseeds and soil: comparison with existing methods","volume":"20","author":"Omirou","year":"2009","journal-title":"Phytochem. Anal."},{"key":"10.1016\/j.jep.2016.07.057_bib30","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1093\/jac\/dkn319","article-title":"Antileishmanial activity mediated by apoptosis and structure-based target study of peganine hydrochloride dihydrate: an approach for rational drug design","volume":"62","author":"Pragya","year":"2008","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.jep.2016.07.057_bib31","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1002\/jssc.201100995","article-title":"Separation and purification of furanocoumarins from Toddalia asiatica (L.) Lam. using microwave-assisted extraction coupled with high-speed counter-current chromatography","volume":"35","author":"Qiu","year":"2012","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.jep.2016.07.057_bib32","series-title":"Screening of Chinese Herbs With Acaricidal Activity and Studying on Acaricidal Active Compounds from Eugenia Caryphyllata","author":"Ruan","year":"2005"},{"key":"10.1016\/j.jep.2016.07.057_bib33","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1007\/BF03356312","article-title":"Evidence of antifungal activity of wild rue (Peganum harmala L.) on phytopathogenic fungi","volume":"116","author":"Sarpeleh","year":"2009","journal-title":"J. Plant Dis. Prot."},{"key":"10.1016\/j.jep.2016.07.057_bib34","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1128\/CMR.00042-06","article-title":"Problems in diagnosing Scabies, a global disease in human and animal populations","volume":"20","author":"Walton","year":"2007","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.jep.2016.07.057_bib35","first-page":"211","article-title":"Analysis of harmine and harmaline of Peganum harmala in different parts and different localities","volume":"37","author":"Wang","year":"2002","journal-title":"Chin. Pharm. J."},{"key":"10.1016\/j.jep.2016.07.057_bib36","article-title":"Chemical fingerprint and simultaneous determination of alkaloids and flavonoids in aerial parts of genus Peganum indigenous to China based on HPLC-UV: application of analysis on secondary metabolites accumulation","author":"Wen","year":"2013","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.jep.2016.07.057_bib37","first-page":"178","article-title":"Study on the toxicity of total alkaloid of Peganum harmala","volume":"19","author":"Yang","year":"1998","journal-title":"Acad. J. Sun. Yat-Sen. Univ. (Med. Sci.)"},{"key":"10.1016\/j.jep.2016.07.057_bib38","first-page":"350","article-title":"Study on the Extraction Method of Alkaloids from of Peganum harmala L","volume":"16","author":"Zhang","year":"1993","journal-title":"Acta Acad. Med."},{"key":"10.1016\/j.jep.2016.07.057_bib39","first-page":"333","article-title":"Chemical constituents and pharmacologic actions of genus Peganum: research advances","volume":"37","author":"Zhao","year":"2010","journal-title":"J. Int. Pharm. Res."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116304822?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116304822?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,10]],"date-time":"2018-09-10T08:50:31Z","timestamp":1536569431000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874116304822"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":39,"alternative-id":["S0378874116304822"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2016.07.057","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Microwave-assisted extraction of three bioactive alkaloids from Peganum harmala L. and their acaricidal activity against Psoroptes cuniculi in vitro","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2016.07.057","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}