{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T17:40:12Z","timestamp":1784310012926,"version":"3.55.0"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100019065","name":"Tianjin Municipal Science and Technology Program","doi-asserted-by":"publisher","award":["14JCYBJC26200"],"award-info":[{"award-number":["14JCYBJC26200"]}],"id":[{"id":"10.13039\/501100019065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81273915"],"award-info":[{"award-number":["81273915"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81470187"],"award-info":[{"award-number":["81470187"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.jep.2016.08.029","type":"journal-article","created":{"date-parts":[[2016,8,24]],"date-time":"2016-08-24T05:31:54Z","timestamp":1472016714000},"page":"333-344","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":75,"special_numbering":"C","title":["Protective effects of triptolide on TLR4 mediated autoimmune and inflammatory response induced myocardial fibrosis in diabetic cardiomyopathy"],"prefix":"10.1016","volume":"193","author":[{"given":"Xin","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-jun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan-shan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ze-jun","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-na","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-yu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao-cheng","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-ming","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2016.08.029_bib1","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/j.amjmed.2008.03.046","article-title":"Diabetic cardiomyopathy: insights into pathogenesis, diagnostic challenges, and therapeutic options","volume":"121","author":"Aneja","year":"2008","journal-title":"Am. J. Med."},{"issue":"4","key":"10.1016\/j.jep.2016.08.029_bib2","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.jacc.2005.09.050","article-title":"The pathogenesis of myocardial fibrosis in the setting of diabetic cardiomyopathy","volume":"47","author":"Asbun","year":"2006","journal-title":"J. Am. Coll. Cardiol."},{"issue":"25","key":"10.1016\/j.jep.2016.08.029_bib3","doi-asserted-by":"crossref","first-page":"3213","DOI":"10.1161\/CIRCULATIONAHA.106.679597","article-title":"Diabetic cardiomyopathy revisited","volume":"115","author":"Boudina","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.jep.2016.08.029_bib4","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/nrcardio.2010.35","article-title":"Intensive glycemic control and cardiovascular disease: an update","volume":"7","author":"Brown","year":"2010","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.jep.2016.08.029_bib5","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.diabet.2011.11.006","article-title":"Inflammation and type 2 diabetes","volume":"38","author":"Calle","year":"2012","journal-title":"Diabetes Metab."},{"key":"10.1016\/j.jep.2016.08.029_bib6","doi-asserted-by":"crossref","first-page":"2144","DOI":"10.1210\/en.2012-2080","article-title":"Renal protective effects of toll-like receptor 4 signaling blockade in type 2 diabetic mice","volume":"154","author":"Cha","year":"2013","journal-title":"Endocrinology"},{"key":"10.1016\/j.jep.2016.08.029_bib7","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1093\/cvr\/cvq308","article-title":"Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart","volume":"89","author":"Creemers","year":"2011","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.jep.2016.08.029_bib8","doi-asserted-by":"crossref","first-page":"861","DOI":"10.2337\/dc09-1799","article-title":"Increased toll-like receptor (TLR) activation and TLR ligands in recently diagnosed type 2 diabetic subjects","volume":"33","author":"Dasu","year":"2010","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jep.2016.08.029_bib9","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1210\/jc.2007-2185","article-title":"Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state","volume":"93","author":"Devaraj","year":"2008","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jep.2016.08.029_bib10","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1007\/s00125-009-1394-8","article-title":"Increased levels of ligands of toll-like receptors 2 and 4 in type 1 diabetes","volume":"52","author":"Devaraj","year":"2009","journal-title":"Diabetologia"},{"key":"10.1016\/j.jep.2016.08.029_bib11","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.metabol.2010.01.005","article-title":"Demonstration of increased toll-like receptor 2 and toll-like receptor 4 expression in monocytes of type 1 diabetes mellitus patients with microvascular complications","volume":"60","author":"Devaraj","year":"2011","journal-title":"Metabolism"},{"key":"10.1016\/j.jep.2016.08.029_bib12","doi-asserted-by":"crossref","unstructured":"Devaraj, S., Tobias, P., Jialal, I., 2011b. Corrigendum to \u201cKnockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes\u201d, Cytokine 55, Cytokine, pp. 441\u2013445.","DOI":"10.1016\/j.cyto.2011.03.023"},{"key":"10.1016\/j.jep.2016.08.029_bib14","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1038\/nri2925","article-title":"Type 2 diabetes as an inflammatory disease","volume":"11","author":"Donath","year":"2011","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jep.2016.08.029_bib15","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1161\/circ.105.10.1158","article-title":"Expression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation","volume":"105","author":"Edfeldt","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jep.2016.08.029_bib16","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/s10741-011-9257-z","article-title":"Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment","volume":"17","author":"Falc\u00e3o-Pires","year":"2012","journal-title":"Heart Fail. Rev."},{"key":"10.1016\/j.jep.2016.08.029_bib17","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1210\/er.2003-0012","article-title":"Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications","volume":"25","author":"Fang","year":"2004","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.jep.2016.08.029_bib18","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/1479-5876-11-134","article-title":"Treatment of diabetic nephropathy with Tripterygium wilfordii Hook F extract: a prospective, randomized, controlled clinical trial","volume":"11","author":"Ge","year":"2013","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.jep.2016.08.029_bib19","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/nrm1983","article-title":"Regulation of cardiac hypertrophy by intracellular signalling pathways","volume":"7","author":"Heineke","year":"2006","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jep.2016.08.029_bib20","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.molmed.2007.09.002","article-title":"Signaling to NF-kappaB by toll-like receptors","volume":"13","author":"Kawai","year":"2007","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.jep.2016.08.029_bib21","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/ni.1863","article-title":"The role of pattern-recognition receptors in innate immunity: update on toll-like receptors","volume":"11","author":"Kawai","year":"2010","journal-title":"Nat. Immunol."},{"issue":"009","key":"10.1016\/j.jep.2016.08.029_bib22","first-page":"541","article-title":"Effect of tripterygium wilfordii polyglucosides on the expression of tumor necrosis factor-\u03b1 and interleukin-4 in renal tissue from rats with diabetic nephropathy","volume":"5","author":"Kong","year":"2013","journal-title":"Chin. J. Diabetes Mellit."},{"key":"10.1016\/j.jep.2016.08.029_bib23","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1002\/jcp.22322","article-title":"The origin of fibroblasts and mechanism of cardiac fibrosis","volume":"225","author":"Krenning","year":"2010","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.jep.2016.08.029_bib24","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/1475-2840-11-111","article-title":"\u03b1-Lipoic acid attenuates cardiac fibrosis in Otsuka Long-Evans Tokushima fatty rats","volume":"11","author":"Lee","year":"2012","journal-title":"Cardiovasc. Diabetol."},{"issue":"1","key":"10.1016\/j.jep.2016.08.029_bib25","first-page":"1","article-title":"Cardiac fibrosis and dysfunction in experimental diabetic cardiomyopathy are ameliorated by alpha-lipoic acid","volume":"11","author":"Li","year":"2012","journal-title":"J. Cardiovasc. Diabetol."},{"key":"10.1016\/j.jep.2016.08.029_bib26","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1681\/ASN.2010111210","article-title":"Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy","volume":"23","author":"Lin","year":"2012","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.jep.2016.08.029_bib27","doi-asserted-by":"crossref","DOI":"10.1155\/2011\/652097","article-title":"Potential role of nuclear factor kappa B in diabetic cardiomyopathy","author":"Lorenzo","year":"2011","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.jep.2016.08.029_bib28","first-page":"9","article-title":"TLR4 activation promotes podocyte injury and interstitial fibrosis in diabetic nephropathy","author":"Ma","year":"2014","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.jep.2016.08.029_bib29","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.lfs.2012.10.028","article-title":"Molecular and metabolic mechanisms of cardiac dysfunction in diabetes","volume":"92","author":"Mandavia","year":"2013","journal-title":"Life Sci."},{"key":"10.1016\/j.jep.2016.08.029_bib31","doi-asserted-by":"crossref","first-page":"2654","DOI":"10.1161\/CIRCULATIONAHA.104.498865","article-title":"Expansion of circulating toll-like receptor 4-positive monocytes in patients with acute coronary syndrome","volume":"111","author":"Methe","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.jep.2016.08.029_bib32","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/nrneph.2011.51","article-title":"Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy","volume":"7","author":"Navarro-Gonz\u00e1lez","year":"2011","journal-title":"Nat. Rev. Nephrol."},{"issue":"12","key":"10.1016\/j.jep.2016.08.029_bib33","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1161\/01.RES.0000130526.20854.fa","article-title":"Inflammatory cytokines and postmyocardial infarction remodeling","volume":"94","author":"Nian","year":"2004","journal-title":"Circ. Res."},{"key":"10.1016\/j.jep.2016.08.029_bib34","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.2337\/db08-0038","article-title":"Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects","volume":"57","author":"Reyna","year":"2008","journal-title":"Diabetes"},{"key":"10.1016\/j.jep.2016.08.029_bib35","doi-asserted-by":"crossref","first-page":"6954","DOI":"10.4049\/jimmunol.180.10.6954","article-title":"Toll-like receptor-4 modulates survival by induction of left ventricular remodeling after myocardial infarction in mice","volume":"180","author":"Riad","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.jep.2016.08.029_bib36","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ijcard.2005.06.023","article-title":"Activated toll-like receptor 4 in monocytes is associated with heart failure after acute myocardial infarction","volume":"109","author":"Satoh","year":"2006","journal-title":"Int J. Cardiol."},{"issue":"3","key":"10.1016\/j.jep.2016.08.029_bib37","doi-asserted-by":"crossref","first-page":"200","DOI":"10.7555\/JBR.26.20110054","article-title":"Sitagliptin, sitagliptin and metformin, or sitagliptin and amitriptyline attenuate streptozotocin-nicotinamide induced diabetic neuropathy in rats[J]","volume":"26","author":"Sharma","year":"2012","journal-title":"J. Biomed. Res."},{"key":"10.1016\/j.jep.2016.08.029_bib38","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.ejps.2012.04.018","article-title":"Curcumin prevents diabetic cardiomyopathy in streptozotocin-induced diabetic rats: possible involvement of PKC-MAPK signaling pathway","volume":"47","author":"Soetikno","year":"2012","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.jep.2016.08.029_bib39","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1475-2840-10-29","article-title":"Screening for left ventricular hypertrophy in patients with type 2 diabetes mellitus in the community","volume":"10","author":"Somaratne","year":"2011","journal-title":"Cardiovasc Diabetol."},{"key":"10.1016\/j.jep.2016.08.029_bib40","doi-asserted-by":"crossref","first-page":"812","DOI":"10.2337\/diabetes.52.3.812","article-title":"Inflammatory cytokines and the risk to develop Type 2 diabetes: results of the prospective population-based european prospective investigation into cancer and nutrition (EPIC) \u2013 potsdam study","volume":"52","author":"Spranger","year":"2003","journal-title":"Diabetes"},{"issue":"3","key":"10.1016\/j.jep.2016.08.029_bib41","first-page":"451","article-title":"Animal models in type 2 diabetes research: an overview","volume":"125","author":"Srinivasan","year":"2007","journal-title":"J. Indian J. Med. Res."},{"key":"10.1016\/j.jep.2016.08.029_bib42","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1161\/CIRCULATIONAHA.106.643585","article-title":"Tumor necrosis factor-alpha mediates cardiac remodeling and ventricular dysfunction after pressure overload state","volume":"115","author":"Sun","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.jep.2016.08.029_bib43","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1475-2840-10-12","article-title":"Regular physical exercise training assists in preventing type 2 diabetes development: focus on its antioxidant and anti-inflammatory properties","volume":"10","author":"Teixeira-Lemos","year":"2011","journal-title":"Cardiovasc Diabetol."},{"key":"10.1016\/j.jep.2016.08.029_bib44","doi-asserted-by":"crossref","first-page":"H1645","DOI":"10.1152\/ajpheart.01107.2001","article-title":"TLR4 inactivation and rBPI(21) block burn-induced myocardial contractile dysfunction","volume":"283","author":"Thomas","year":"2002","journal-title":"Am. J. Physiol. Hear. Circ. Physiol."},{"key":"10.1016\/j.jep.2016.08.029_bib45","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1161\/CIRCRESAHA.107.158220","article-title":"Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction","volume":"102","author":"Timmers","year":"2008","journal-title":"Circ. Res."},{"key":"10.1016\/j.jep.2016.08.029_bib46","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/nrcardio.2009.199","article-title":"Myocardial remodeling after infarction: the role of myofibroblasts","volume":"7","author":"Van den Borne","year":"2010","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.jep.2016.08.029_bib47","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.2337\/db12-1025","article-title":"Glucagon-like peptide-1 protects against cardiac microvascular injury in diabetes via a cAMP\/PKA\/Rho-dependent mechanism","volume":"62","author":"Wang","year":"2013","journal-title":"Diabetes"},{"key":"10.1016\/j.jep.2016.08.029_bib48","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/1475-2840-12-50","article-title":"Anti-inflammatory effects of triptolide improve left ventricular function in a rat model of diabetic cardiomyopathy","volume":"12","author":"Wen","year":"2013","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.jep.2016.08.029_bib49","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.2337\/db06-1662","article-title":"Cardioprotective and anti-inflammatory effects of interleukin converting enzyme inhibition in experimental diabetic cardiomyopathy","volume":"56","author":"Westermann","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.jep.2016.08.029_bib50","first-page":"106","article-title":"Cellular and molecular mechanisms of proteinuria in diabetic nephropathy","author":"Wolf","year":"2007","journal-title":"Nephron \u2013 Physiol."},{"key":"10.1016\/j.jep.2016.08.029_bib51","doi-asserted-by":"crossref","DOI":"10.3892\/ijmm.17.1.141","article-title":"Triptolide attenuates oxidative stress, NF-kappaB activation and multiple cytokine gene expression in murine peritoneal macrophage","author":"Wu","year":"2006","journal-title":"Int. J. Mol. Med"},{"key":"10.1016\/j.jep.2016.08.029_bib52","first-page":"66","article-title":"Metformin attenuates cardiac fibrosis by inhibiting the TGF\u03b21\u2013Smad3 signalling pathway","author":"Xiao","year":"2010","journal-title":"J. Cardiovasc. Res., cvq0"},{"key":"10.1016\/j.jep.2016.08.029_bib53","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1038\/nm1613","article-title":"Endothelial-to-mesenchymal transition contributes to cardiac fibrosis","volume":"13","author":"Zeisberg","year":"2007","journal-title":"Nat. Med."},{"key":"10.1016\/j.jep.2016.08.029_bib54","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1111\/j.1582-4934.2009.00798.x","article-title":"Deficiency in TLR4 signal transduction ameliorates cardiac injury and cardiomyocyte contractile dysfunction during ischemia","volume":"13","author":"Zhao","year":"2009","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.jep.2016.08.029_bib55","doi-asserted-by":"crossref","first-page":"39","DOI":"10.2174\/157339908783502370","article-title":"Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy","volume":"4","author":"Ziyadeh","year":"2008","journal-title":"Curr. Diabetes Rev."}],"updated-by":[{"DOI":"10.1016\/j.jep.2025.119826","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:00:00Z","timestamp":1758758400000}}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116305578?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116305578?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T10:48:30Z","timestamp":1758192510000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874116305578"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":53,"alternative-id":["S0378874116305578"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2016.08.029","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Protective effects of triptolide on TLR4 mediated autoimmune and inflammatory response induced myocardial fibrosis in diabetic cardiomyopathy","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2016.08.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}