{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T12:04:35Z","timestamp":1776859475183,"version":"3.51.2"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.jep.2016.10.082","type":"journal-article","created":{"date-parts":[[2016,11,10]],"date-time":"2016-11-10T22:48:19Z","timestamp":1478818099000},"page":"1112-1121","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":62,"special_numbering":"C","title":["The influence of hydro-ethanolic extract of Portulaca oleracea L. on Th1\/Th2 balance in isolated human lymphocytes"],"prefix":"10.1016","volume":"194","author":[{"given":"Vahid Reza","family":"Askari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed Abdolrahim","family":"Rezaee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalil","family":"Abnous","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehrdad","family":"Iranshahi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Hossein","family":"Boskabady","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6603","key":"10.1016\/j.jep.2016.10.082_bib1","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/383787a0","article-title":"Functional diversity of helper T lymphocytes","volume":"383","author":"Abbas","year":"1996","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.jep.2016.10.082_bib2","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.pestbp.2013.02.004","article-title":"The potential role of Portulaca oleracea as a neuroprotective agent in rotenone-induced neurotoxicity and apoptosis in the brain of rats","volume":"105","author":"Abdel Moneim","year":"2013","journal-title":"Pest. Biochem Physiol."},{"issue":"11","key":"10.1016\/j.jep.2016.10.082_bib3","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1084\/jem.20032058","article-title":"Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells","volume":"199","author":"Akdis","year":"2004","journal-title":"J. Exp. Med"},{"issue":"8","key":"10.1016\/j.jep.2016.10.082_bib4","doi-asserted-by":"crossref","first-page":"3383","DOI":"10.7314\/APJCP.2015.16.8.3383","article-title":"Portulaca oleracea seed oil exerts cytotoxic effects on human liver cancer (HepG2) and human lung cancer (A-549) cell lines","volume":"16","author":"Al-Sheddi","year":"2015","journal-title":"Asian Pac. J. Cancer Prev.: APJCP"},{"issue":"2","key":"10.1016\/j.jep.2016.10.082_bib5","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1097\/COH.0b013e32833647c2","article-title":"Human and murine Th17","volume":"5","author":"Annunziato","year":"2010","journal-title":"Curr. Opin. HIV AIDS"},{"issue":"3","key":"10.1016\/j.jep.2016.10.082_bib6","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.jams.2011.09.008","article-title":"Protective effects of aqueous and ethanolic extracts of Portulaca oleracea L. aerial parts on H 2 O 2-induced DNA damage in lymphocytes by comet assay","volume":"4","author":"Behravan","year":"2011","journal-title":"J. Acupunct. Meridian Stud."},{"key":"10.1016\/j.jep.2016.10.082_bib7","first-page":"187","article-title":"Antitussive effect of Portulaca oleracea L. in guinea pigs","author":"Boroushaki","year":"2010","journal-title":"Iran. J. Pharm. Res.: IJPR"},{"key":"10.1016\/j.jep.2016.10.082_bib8","article-title":"Relaxant effect of Portulaca oleraceae on guinea pig tracheal chains and its possible mechanism (s) of action","author":"Boskabady","year":"2004","journal-title":"Med. Hypotheses Res"},{"issue":"12","key":"10.1016\/j.jep.2016.10.082_bib9","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1089\/jmf.2011.1697","article-title":"The effect of Crocus sativus extract on human lymphocytes' cytokines and T helper 2\/T helper 1 balance","volume":"14","author":"Boskabady","year":"2011","journal-title":"J. Med. Food"},{"issue":"3","key":"10.1016\/j.jep.2016.10.082_bib10","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/j.jep.2013.10.003","article-title":"The impact of Zataria multiflora Boiss extract on in vitro and in vivo Th1\/Th2 cytokine (IFN-\u03b3\/IL4) balance","volume":"150","author":"Boskabady","year":"2013","journal-title":"J. Ethnopharmacol."},{"issue":"3","key":"10.1016\/j.jep.2016.10.082_bib11","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/S0091-6749(97)70255-0","article-title":"Corticosteroid modulation of human, antigen-specific Th1 and Th2 responses","volume":"100","author":"Braun","year":"1997","journal-title":"J. Allergy Clin. Immunol."},{"issue":"4","key":"10.1016\/j.jep.2016.10.082_bib12","first-page":"624","article-title":"Hydrocortisone inhibition of human interleukin-","volume":"77","author":"Byron","year":"1992","journal-title":"Immunology"},{"issue":"8","key":"10.1016\/j.jep.2016.10.082_bib13","doi-asserted-by":"crossref","first-page":"7981","DOI":"10.1007\/s11033-012-1644-6","article-title":"Effects of aqueous extract of Portulaca oleracea L. on oxidative stress and liver, spleen leptin, PAR\u03b1 and FAS mRNA expression in high-fat diet induced mice","volume":"39","author":"Chen","year":"2012","journal-title":"Mol. Biol. Rep."},{"issue":"6","key":"10.1016\/j.jep.2016.10.082_bib14","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1007\/s10719-010-9307-0","article-title":"Sulfated modification and cytotoxicity of Portulaca oleracea L. polysaccharides","volume":"27","author":"Chen","year":"2010","journal-title":"Glycoconj. J."},{"issue":"9","key":"10.1016\/j.jep.2016.10.082_bib15","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1084\/jem.190.9.1309","article-title":"T helper 1 cells and interferon \u03b3 regulate allergic airway inflammation and mucus production","volume":"190","author":"Cohn","year":"1999","journal-title":"J. Exp. Med"},{"issue":"8","key":"10.1016\/j.jep.2016.10.082_bib16","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1111\/j.1398-9995.2011.02576.x","article-title":"Th17 cells: new players in asthma pathogenesis","volume":"66","author":"Cosmi","year":"2011","journal-title":"Allergy"},{"issue":"9","key":"10.1016\/j.jep.2016.10.082_bib17","first-page":"1589","article-title":"Antioxidant effect of purslane (Portulaca oleracea) and its mechanism of action","volume":"5","author":"Dkhil","year":"2011","journal-title":"J. Med. Plants Res."},{"issue":"5","key":"10.1016\/j.jep.2016.10.082_bib18","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/s00262-006-0225-8","article-title":"Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients","volume":"56","author":"Ghiringhelli","year":"2007","journal-title":"Cancer Immunol., Immunother.: CII"},{"key":"10.1016\/j.jep.2016.10.082_bib19","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.fct.2015.08.028","article-title":"Immunomodulatory and cytotoxic effects of Nigella sativa and thymoquinone on rat splenocytes","volume":"86","author":"Gholamnezhad","year":"2015","journal-title":"Food Chem. Toxicol.: Int. J. Publ. Br. Ind. Biol. Res. Assoc."},{"issue":"2","key":"10.1016\/j.jep.2016.10.082_bib20","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1152\/japplphysiol.00008.2007","article-title":"Immune function in sport and exercise","volume":"103","author":"Gleeson","year":"2007","journal-title":"J. Appl Physiol."},{"issue":"2","key":"10.1016\/j.jep.2016.10.082_bib21","doi-asserted-by":"crossref","first-page":"7039","DOI":"10.4238\/2015.June.26.13","article-title":"Immunomodulatory effect of bone marrow mesenchymal stem cells on T lymphocytes in patients with decompensated liver cirrhosis","volume":"14","author":"Guo","year":"2015","journal-title":"Genet. Mol. Res.: GMR"},{"issue":"1\u20132","key":"10.1016\/j.jep.2016.10.082_bib22","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0378-8741(02)00205-2","article-title":"Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells","volume":"83","author":"Hong","year":"2002","journal-title":"J. Ethnopharmacol."},{"issue":"1\u20132","key":"10.1016\/j.jep.2016.10.082_bib23","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0378-8741(02)00205-2","article-title":"Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells","volume":"83","author":"Hong","year":"2002","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.10.082_bib24","doi-asserted-by":"crossref","first-page":"327470","DOI":"10.1155\/2015\/327470","article-title":"T Helper Lymphocyte Subsets and Plasticity in Autoimmunity and Cancer: an Overview","volume":"2015","author":"Ivanova","year":"2015","journal-title":"Biomed. Res Int"},{"issue":"5","key":"10.1016\/j.jep.2016.10.082_bib25","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1002\/eji.200322919","article-title":"IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy","volume":"33","author":"Jutel","year":"2003","journal-title":"Eur. J. Immunol."},{"issue":"2","key":"10.1016\/j.jep.2016.10.082_bib26","first-page":"145","article-title":"Review: free radicals, antioxidants, and the immune system","volume":"30","author":"Knight","year":"2000","journal-title":"Ann. Clin. Lab. Sci."},{"issue":"2","key":"10.1016\/j.jep.2016.10.082_bib27","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s11418-010-0505-7","article-title":"Methyl galbanate, a novel inhibitor of nitric oxide production in mouse macrophage RAW264.7 cells","volume":"65","author":"Kohno","year":"2011","journal-title":"J. Nat. Med."},{"issue":"5","key":"10.1016\/j.jep.2016.10.082_bib28","doi-asserted-by":"crossref","first-page":"5628","DOI":"10.3390\/ijms13055628","article-title":"Anti-TNF-\u03b1 activity of Portulaca oleracea in vascular endothelial cells","volume":"13","author":"Lee","year":"2012","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2016.10.082_bib29","first-page":"2012","article-title":"Portulaca oleracea ameliorates diabetic vascular inflammation and endothelial dysfunction in db\/db mice","author":"Lee","year":"2012","journal-title":"Evid. Based Complement Altern. Med."},{"key":"10.1016\/j.jep.2016.10.082_bib30","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.ijbiomac.2014.04.038","article-title":"Evaluation of antioxidant and immuno-enhancing activities of Purslane polysaccharides in gastric cancer rats","volume":"68","author":"Li","year":"2014","journal-title":"Int. J. Biol. Macromol."},{"issue":"3","key":"10.1016\/j.jep.2016.10.082_bib31","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.foodchem.2006.09.025","article-title":"Antioxidant properties of different cultivars of Portulaca oleracea","volume":"103","author":"Lim","year":"2007","journal-title":"Food Chem."},{"issue":"2","key":"10.1016\/j.jep.2016.10.082_bib32","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.carbpol.2009.01.008","article-title":"Sulfation of a polysaccharide obtained from Phellinus ribis and potential biological activities of the sulfated derivatives","volume":"77","author":"Liu","year":"2009","journal-title":"Carbohydr. Polym."},{"issue":"5","key":"10.1016\/j.jep.2016.10.082_bib33","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/BF02977761","article-title":"Production of cytokine and NO by RAW 264.7 macrophages and PBMC in vitro incubation with flavonoids","volume":"28","author":"Lyu","year":"2005","journal-title":"Arch. Pharm. Res"},{"issue":"1","key":"10.1016\/j.jep.2016.10.082_bib34","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.jep.2004.03.015","article-title":"Bronchodilatory effect of Portulaca oleracea in airways of asthmatic patients","volume":"93","author":"Malek","year":"2004","journal-title":"J. Ethnopharmacol."},{"issue":"1\u20133","key":"10.1016\/j.jep.2016.10.082_bib35","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s10661-005-9117-1","article-title":"Effects of copper sulfate and copper nitrate in aquatic medium on the restoration potential and accumulation of copper in stem cuttings of the terrestrial medicinal plant, Portulaca oleracea linn","volume":"121","author":"Mohanapriya","year":"2006","journal-title":"Environ. Monit. Assess."},{"issue":"4","key":"10.1016\/j.jep.2016.10.082_bib36","first-page":"895","article-title":"The Significance Application of Indigenous Phytohemagglutinin (PHA) Mitogen on Metaphase and Cell Culture Procedure","volume":"10","author":"Movafagh","year":"2011","journal-title":"Iran. J. Pharm. Res.: IJPR"},{"issue":"1","key":"10.1016\/j.jep.2016.10.082_bib37","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1006\/cimm.1998.1259","article-title":"Adrenal hormone modulation of type 1 and type 2 cytokine production by spleen cells: dexamethasone and dehydroepiandrosterone suppress interleukin-2, interleukin-4, and interferon-gamma production in vitro","volume":"184","author":"Moynihan","year":"1998","journal-title":"Cell. Immunol."},{"issue":"1","key":"10.1016\/j.jep.2016.10.082_bib38","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/mi.2010.51","article-title":"The oral administration of bacterial extracts prevents asthma via the recruitment of regulatory T cells to the airways","volume":"4","author":"Navarro","year":"2011","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.jep.2016.10.082_bib39","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/s004210050175","article-title":"Lymphocyte proliferation in response to exercise","volume":"75","author":"Nielsen","year":"1997","journal-title":"Eur. J. Appl Physiol. Occup. Physiol."},{"issue":"2","key":"10.1016\/j.jep.2016.10.082_bib40","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.coi.2011.12.004","article-title":"Transcriptional mechanisms that regulate T helper 1 cell differentiation","volume":"24","author":"Oestreich","year":"2012","journal-title":"Curr. Opin. Immunol."},{"issue":"2","key":"10.1016\/j.jep.2016.10.082_bib41","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.leukres.2004.06.003","article-title":"High Th1\/Th2 ratio in patients with multiple myeloma","volume":"29","author":"Ogawara","year":"2005","journal-title":"Leuk. Res."},{"issue":"10","key":"10.1016\/j.jep.2016.10.082_bib42","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1164\/rccm.200905-0686OC","article-title":"House dust mite sublingual immunotherapy: the role for transforming growth factor\u2013\u03b2 and functional regulatory T cells","volume":"180","author":"O'Hehir","year":"2009","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"1","key":"10.1016\/j.jep.2016.10.082_bib43","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0378-8741(87)90098-5","article-title":"Investigation into the mechanism of action of extracts of Portulaca oleracea","volume":"21","author":"Okwuasaba","year":"1987","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.jep.2016.10.082_bib44","doi-asserted-by":"crossref","first-page":"238","DOI":"10.3923\/jms.2007.238.242","article-title":"Calcium ions influences smooth muscle relaxant response to aqueous extract of Portulaca oleracea","volume":"7","author":"Oluwole","year":"2007","journal-title":"J. Med. Sci."},{"key":"10.1016\/j.jep.2016.10.082_bib45","article-title":"The anti-tumor efficacy of IL-2\/IL-21-cultured polyfunctional neu-specific T-cells is TNF-alpha\/IL-17 dependent","author":"Phan-Lai","year":"2015","journal-title":"Clin. Cancer Res.: Off. J. Am. Assoc. Cancer Res."},{"issue":"7","key":"10.1016\/j.jep.2016.10.082_bib46","doi-asserted-by":"crossref","first-page":"2406","DOI":"10.4049\/jimmunol.156.7.2406","article-title":"Glucocorticoids promote a TH2 cytokine response by CD4+ T cells in vitro","volume":"156","author":"Ramirez","year":"1996","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.jep.2016.10.082_bib47","first-page":"226","article-title":"Evaluation of the anti-nociceptive and anti-inflammatory activities of the pet: ether Extract of Portulaca oleracea (Linn.)","volume":"6","author":"Rao","year":"2012","journal-title":"J. Clin. Diagn. Res"},{"issue":"1","key":"10.1016\/j.jep.2016.10.082_bib48","first-page":"37","article-title":"Investigation of the active constituents of Portulaca oleraceae L. (Portulacaceae) growing in Jordan","volume":"17","author":"Rasheed","year":"2004","journal-title":"Pak. J. Pharm. Sci."},{"issue":"4","key":"10.1016\/j.jep.2016.10.082_bib49","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.smim.2011.04.003","article-title":"Making sense of regulatory T cell suppressive function","volume":"23","author":"Shalev","year":"2011","journal-title":"Semin. Immunol."},{"issue":"8","key":"10.1016\/j.jep.2016.10.082_bib50","doi-asserted-by":"crossref","first-page":"10257","DOI":"10.3390\/ijms130810257","article-title":"Evaluation of antioxidant properties and mineral composition of purslane (Portulaca oleracea L.) at different growth stages","volume":"13","author":"Uddin","year":"2012","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2016.10.082_bib51","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1155\/2014\/951019","article-title":"Purslane weed (Portulaca oleracea): a prospective plant source of nutrition, omega-3 fatty acid, and antioxidant attributes","volume":"2014","author":"Uddin","year":"2014","journal-title":"Sci. World J."},{"issue":"4","key":"10.1016\/j.jep.2016.10.082_bib52","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.jnutbio.2010.12.015","article-title":"Ethanol extract of Portulaca oleracea L. protects against hypoxia-induced neuro damage through modulating endogenous erythropoietin expression","volume":"23","author":"Wanyin","year":"2012","journal-title":"J. Nutr. Biochem."},{"issue":"7","key":"10.1016\/j.jep.2016.10.082_bib53","doi-asserted-by":"crossref","first-page":"e41373","DOI":"10.1371\/journal.pone.0041373","article-title":"TH17, TH22 and Treg cells are enriched in the healthy human cecum","volume":"7","author":"Wolff","year":"2012","journal-title":"PLoS One"},{"issue":"16","key":"10.1016\/j.jep.2016.10.082_bib54","doi-asserted-by":"crossref","first-page":"6905","DOI":"10.1021\/jf801101u","article-title":"Isolation and characterization of immunostimulatory polysaccharide from an herb tea, Gynostemma pentaphyllum Makino","volume":"56","author":"Yang","year":"2008","journal-title":"J. Agric Food Chem."},{"issue":"6","key":"10.1016\/j.jep.2016.10.082_bib55","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1007\/s00044-011-9582-8","article-title":"Acetylcholinesterase inhibitory activity of the total alkaloid from traditional Chinese herbal medicine for treating Alzheimer's disease","volume":"21","author":"Yang","year":"2012","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.jep.2016.10.082_bib56","first-page":"1","article-title":"In vitro anti-inflammatory and immunomodulatory properties of umbelliprenin and methyl galbanate","author":"Zamani Taghizadeh Rabe","year":"2015","journal-title":"J. Immunotoxicol."},{"issue":"2","key":"10.1016\/j.jep.2016.10.082_bib57","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.carbpol.2013.04.023","article-title":"Antitumor activity of Portulaca oleracea L. polysaccharides against cervical carcinoma in vitro and in vivo","volume":"96","author":"Zhao","year":"2013","journal-title":"Carbohydr. Polym."},{"issue":"1","key":"10.1016\/j.jep.2016.10.082_bib58","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1590\/S1984-82502012000100018","article-title":"HPLC method for the simultaneous determination of four compounds in rat plasma after intravenous administration of Portulaca oleracea L. extract","volume":"48","author":"Zhongzhe","year":"2012","journal-title":"Braz. J. Pharm. Sci."},{"issue":"2","key":"10.1016\/j.jep.2016.10.082_bib59","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1007\/s12161-009-9091-2","article-title":"Analysis of flavonoids in Portulaca oleracea L. by UV\u2013vis spectrophotometry with comparative study on different extraction technologies","volume":"3","author":"Zhu","year":"2010","journal-title":"Food Anal. Methods"},{"issue":"3","key":"10.1016\/j.jep.2016.10.082_bib60","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1021\/jf802687t","article-title":"Characterization and free radical scavenging activity of rapeseed meal polysaccharides WPS-1 and APS-2","volume":"57","author":"Zhu","year":"2009","journal-title":"J. Agric Food Chem."},{"issue":"11","key":"10.1016\/j.jep.2016.10.082_bib61","doi-asserted-by":"crossref","first-page":"2470","DOI":"10.1016\/j.celrep.2015.11.046","article-title":"T cell intrinsic USP15 deficiency promotes excessive IFN-gamma production and an immunosuppressive tumor microenvironment in MCA-induced fibrosarcoma","volume":"13","author":"Zou","year":"2015","journal-title":"Cell Rep."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116316269?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116316269?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T21:36:23Z","timestamp":1692567383000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874116316269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":61,"alternative-id":["S0378874116316269"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2016.10.082","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The influence of hydro-ethanolic extract of Portulaca oleracea L. on Th1\/Th2 balance in isolated human lymphocytes","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2016.10.082","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}