{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T23:14:12Z","timestamp":1780096452511,"version":"3.54.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,12,24]],"date-time":"2017-12-24T00:00:00Z","timestamp":1514073600000},"content-version":"vor","delay-in-days":357,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"FCS\/UFGD"},{"DOI":"10.13039\/501100002322","name":"CAPES","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005672","name":"FUNDECT","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005672","id-type":"DOI","asserted-by":"crossref"}]},{"name":"CPBIO\/UEMS"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.jep.2016.12.024","type":"journal-article","created":{"date-parts":[[2016,12,15]],"date-time":"2016-12-15T01:38:36Z","timestamp":1481765916000},"page":"193-200","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Alibertia edulis (L.C. Rich.) A.C. Rich \u2013 A potent diuretic arising from Brazilian indigenous species"],"prefix":"10.1016","volume":"196","author":[{"given":"Diana Figueiredo","family":"de Santana Aquino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cleide Adriane","family":"Signor Tirloni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara Em\u00edlia Lima","family":"Tolouei Menegati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Andrea","family":"Lima Cardoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia Cristina","family":"Heredia Vieira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria do","family":"Carmo Vieira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Mar\u00eda","family":"Simonet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Antonio","family":"Mac\u00edas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Junior","given":"Arquimedes","family":"Gasparotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2016.12.024_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2005.03.005","article-title":"Diuretic activity of Artemisia thuscula, an endemic Canary species","volume":"100","author":"Benjumea","year":"2005","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.jep.2016.12.024_bib2","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1006\/abio.1996.0292","article-title":"The ferric reducing ability of plasma (FRAP) as a measure of \u201cantioxidant power\u201d: the FRAP assay","volume":"239","author":"Benzie","year":"1996","journal-title":"Anal. Biochem."},{"issue":"2","key":"10.1016\/j.jep.2016.12.024_bib3","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0031-9422(97)00238-0","article-title":"Iridoids from Tocoyena formosa","volume":"46","author":"Bolzani","year":"1997","journal-title":"Phytochemistry"},{"issue":"5","key":"10.1016\/j.jep.2016.12.024_bib4","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1016\/S0031-9422(00)89654-5","article-title":"An oleanane acid from Alibertia edulis","volume":"36","author":"Brochini","year":"1994","journal-title":"Phytochemistry"},{"issue":"1","key":"10.1016\/j.jep.2016.12.024_bib5","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1590\/S0102-33062005000100005","article-title":"Medicinal plants used by the Kaiow\u00e1 and Guarani indigenous populations in the Caarap\u00f3 Reserve, Mato Grosso do Sul","volume":"19","author":"Bueno","year":"2005","journal-title":"Acta Bot. Bras."},{"issue":"11","key":"10.1016\/j.jep.2016.12.024_bib6","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1345\/aph.1R212","article-title":"Thiazide diuretics as chronic antihypertensive therapy in patients with severe renal disease\u2014is there a role in the absence of diuresis?","volume":"46","author":"Chan","year":"2012","journal-title":"Ann. Pharmacother."},{"issue":"36","key":"10.1016\/j.jep.2016.12.024_bib7","doi-asserted-by":"crossref","first-page":"8809","DOI":"10.1021\/jf300669s","article-title":"Citrus flavanones: what is their role in cardiovascular protection?","volume":"60","author":"Chanet","year":"2012","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jep.2016.12.024_bib8","first-page":"178","article-title":"Estimation of total flavonoid content in propolis by two complementary colorimetric methods","volume":"10","author":"Chang","year":"2002","journal-title":"J. Food Drug Anal."},{"issue":"3","key":"10.1016\/j.jep.2016.12.024_bib9","doi-asserted-by":"crossref","first-page":"e20140114","DOI":"10.1590\/1676-06032014011414","article-title":"Subterranean biodiversity in the Serra da Bodoquena karst area, Paraguay river basin, Mato Grosso do Sul, Southwestern Brazil","volume":"14","author":"Cordeiro","year":"2014","journal-title":"Biota Neotrop."},{"issue":"7","key":"10.1016\/j.jep.2016.12.024_bib10","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1002\/hlca.200890147","article-title":"New antifungal terpenoid glycosides from Alibertia edulis (Rubiaceae)","volume":"91","author":"Da Silva","year":"2008","journal-title":"Helv. Chim. Acta"},{"issue":"6","key":"10.1016\/j.jep.2016.12.024_bib11","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1021\/np50012a001","article-title":"Iridoids. A review","volume":"43","author":"El-Naggar","year":"1980","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.jep.2016.12.024_bib12","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.jep.2009.01.021","article-title":"Natriuretic and diuretic effects of Tropaeolum majus (Tropaeolaceae) in rats","volume":"122","author":"Gasparotto Junior","year":"2009","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.024_bib13","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1472-6882-11-13","article-title":"Bioprotective properties of Dragon's blood resin: in vitro evaluation of antioxidant activity and antimicrobial activity","volume":"11","author":"Gupta","year":"2011","journal-title":"BMC Complement. Altern. Med."},{"issue":"1","key":"10.1016\/j.jep.2016.12.024_bib14","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1076\/phbi.34.1.19.13180","article-title":"Screening of Panamanian medicinal plants for brine shrimp toxicity, crown gall tumor inhibition, cytotoxicity and DNA intercalation","volume":"34","author":"Gupta","year":"1996","journal-title":"Int. J. Pharmacogn."},{"issue":"3","key":"10.1016\/j.jep.2016.12.024_bib15","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.mcna.2009.02.015","article-title":"Oxidative stress and hypertension","volume":"93","author":"Harrison","year":"2009","journal-title":"Med. Clin. N. Am."},{"issue":"2","key":"10.1016\/j.jep.2016.12.024_bib16","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.phymed.2015.12.012","article-title":"Polyphenol protection and treatment of hypertension","volume":"23","author":"H\u00fcgel","year":"2016","journal-title":"Phytomedicine"},{"issue":"18","key":"10.1016\/j.jep.2016.12.024_bib17","doi-asserted-by":"crossref","first-page":"3955","DOI":"10.1113\/jphysiol.2014.271676","article-title":"Pressure natriuresis and the renal control of arterial blood pressure","volume":"592","author":"Ivy","year":"2014","journal-title":"J. Physiol."},{"issue":"25","key":"10.1016\/j.jep.2016.12.024_bib18","first-page":"1","article-title":"Neuroprotective and anti-oxidant effects of caffeic acid isolated from Erigeron annuus leaf","volume":"6","author":"Jeong","year":"2011","journal-title":"Chin. Med."},{"key":"10.1016\/j.jep.2016.12.024_bib19","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0160-5402(84)90054-8","article-title":"A method for screening diuretic agents in the rat","volume":"11","author":"Kau","year":"1984","journal-title":"J. Pharmacol. Methods"},{"issue":"6","key":"10.1016\/j.jep.2016.12.024_bib20","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1159\/000082314","article-title":"Long-term adaptation of renal ion transporters to chronic diuretic treatment","volume":"24","author":"Kim","year":"2004","journal-title":"Am. J. Nephrol."},{"issue":"3","key":"10.1016\/j.jep.2016.12.024_bib21","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.jep.2011.01.017","article-title":"The future is written: Impact of scripts on the cognition, selection, knowledge and transmission of medicinal plant use and its implications for ethnobotany and ethnopharmacology","volume":"134","author":"Leonti","year":"2011","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.jep.2016.12.024_bib22","doi-asserted-by":"crossref","first-page":"141","DOI":"10.3164\/jcbn.40.141","article-title":"Antihypertensive and antioxidant action of amlodipine and vitamin C in patients of essential hypertension","volume":"40","author":"Mahajan","year":"2007","journal-title":"J. Clin. Biochem. Nutr."},{"issue":"7","key":"10.1016\/j.jep.2016.12.024_bib23","doi-asserted-by":"crossref","first-page":"13422","DOI":"10.3390\/molecules200713422","article-title":"Secondary metabolites from Rubiaceae species","volume":"20","author":"Martins","year":"2015","journal-title":"Molecules"},{"issue":"24","key":"10.1016\/j.jep.2016.12.024_bib24","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1038\/35002501","article-title":"Biodiversity hotspots for conservation priorities","volume":"403","author":"Myers","year":"2000","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.jep.2016.12.024_bib25","doi-asserted-by":"crossref","first-page":"17","DOI":"10.5049\/EBP.2015.13.1.17","article-title":"Loop diuretics in clinical practice","volume":"13","author":"Oh","year":"2015","journal-title":"Electrolyte Blood Press."},{"issue":"7","key":"10.1016\/j.jep.2016.12.024_bib26","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.2307\/2657002","article-title":"Phylogeny of the neotropical Alibertia group (Rubiaceae), with emphasis on the genus Alibertia, inferred from ITS and 5S ribosomal DNA sequences","volume":"87","author":"Persson","year":"2000","journal-title":"Am. J. Bot."},{"issue":"5","key":"10.1016\/j.jep.2016.12.024_bib27","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0041-0101(00)00154-9","article-title":"Plants as source of drugs","volume":"39","author":"Rates","year":"2001","journal-title":"Toxicon"},{"key":"10.1016\/j.jep.2016.12.024_bib28","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1002\/pca.853","article-title":"Isolation and Identification of flavonoids, including flavone rotamers, from the herbal drug \u2018Crataegi folium cum flore\u2019 (Hawthorn)","volume":"16","author":"Rayyan","year":"2005","journal-title":"Phytochem. Anal."},{"issue":"5","key":"10.1016\/j.jep.2016.12.024_bib29","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1007\/s10531-006-9041-x","article-title":"Ant communities, environmental characteristics and their implications for conservation in the Brazilian Pantanal","volume":"16","author":"Ribas","year":"2006","journal-title":"Biodivers. Conserv."},{"issue":"3","key":"10.1016\/j.jep.2016.12.024_bib30","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1093\/trstmh\/trs089","article-title":"Sugar cane manufacturing is associated with tuberculosis in an indigenous population in Brazil","volume":"107","author":"Sacchi","year":"2013","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.jep.2016.12.024_bib31","doi-asserted-by":"crossref","first-page":"173","DOI":"10.17660\/ActaHortic.2002.569.28","article-title":"Levantamento e caracteriza\u00e7\u00e3o de plantas nativas com propriedades medicinais em fragmentos florestais e de cerrado de Dourados-MS, numa vis\u00e3o etnobot\u00e2nica","volume":"19","author":"Sangalli","year":"2002","journal-title":"Acta Hortic."},{"issue":"7","key":"10.1016\/j.jep.2016.12.024_bib32","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/j.1751-7176.2008.08189.x","article-title":"The kidney and hypertension: causes and treatment","volume":"10","author":"Sica","year":"2008","journal-title":"J. Clin. Hypertens."},{"issue":"3","key":"10.1016\/j.jep.2016.12.024_bib33","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1076\/phbi.39.3.161.5925","article-title":"Alkaloid screening of herbarium samples of Rubiaceae from Panam\u00e1","volume":"39","author":"Soto-Sobenis","year":"2001","journal-title":"Pharm. Biol."},{"issue":"7","key":"10.1016\/j.jep.2016.12.024_bib34","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/hr.2010.64","article-title":"Antihypertensive effects of Ocimum basilicum L.(OBL) on blood pressure in renovascular hypertensive rats","volume":"33","author":"Umar","year":"2010","journal-title":"Hypertens. Res."},{"issue":"1","key":"10.1016\/j.jep.2016.12.024_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jep.2007.07.023","article-title":"Herbal medicines as diuretics: a review of the scientific evidence","volume":"114","author":"Wright","year":"2007","journal-title":"J. Ethnopharmacol."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116323704?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116323704?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,22]],"date-time":"2019-08-22T06:26:11Z","timestamp":1566455171000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874116323704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":35,"alternative-id":["S0378874116323704"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2016.12.024","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alibertia edulis (L.C. Rich.) A.C. Rich \u2013 A potent diuretic arising from Brazilian indigenous species","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2016.12.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd.","name":"copyright","label":"Copyright"}]}}