{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:17:23Z","timestamp":1791951443255,"version":"4.3.4"},"reference-count":164,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81503129"],"award-info":[{"award-number":["81503129"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Traditional Chinese Medicine Research Project of Zhejiang Province","award":["2013ZB085"],"award-info":[{"award-number":["2013ZB085"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.jep.2016.12.042","type":"journal-article","created":{"date-parts":[[2016,12,28]],"date-time":"2016-12-28T04:52:00Z","timestamp":1482900720000},"page":"45-63","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":128,"special_numbering":"C","title":["Traditional Chinese medicine for pulmonary fibrosis therapy: Progress and future prospects"],"prefix":"10.1016","volume":"198","author":[{"given":"Liu-Cheng","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lian-Di","family":"Kan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2016.12.042_bib1","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.biocel.2008.06.010","article-title":"Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases","volume":"41","author":"Aggarwal","year":"2009","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.jep.2016.12.042_bib2","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1007\/s10753-012-9491-0","article-title":"Effect of resveratrol on treatment of bleomycin-induced pulmonary fibrosis in rats","volume":"35","author":"Akgedik","year":"2012","journal-title":"Inflammation"},{"key":"10.1016\/j.jep.2016.12.042_bib3","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1749-8546-6-36","article-title":"Boswellic acids extract attenuates pulmonary fibrosis induced by bleomycin and oxidative stress from gamma irradiation in rats","volume":"6","author":"Ali","year":"2011","journal-title":"Chin. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib4","doi-asserted-by":"crossref","first-page":"806","DOI":"10.3109\/13880209.2013.766895","article-title":"Modulation of cyclophosphamide-induced early lung injury by allicin","volume":"51","author":"Ashry","year":"2013","journal-title":"Pharm. Biol."},{"key":"10.1016\/j.jep.2016.12.042_bib5","doi-asserted-by":"crossref","first-page":"e57285","DOI":"10.1371\/journal.pone.0057285","article-title":"Curcumin modulates the inflammatory response and inhibits subsequent fibrosis in a mouse model of viral-induced acute respiratory distress syndrome","volume":"8","author":"Avasarala","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2016.12.042_bib6","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.ejphar.2010.05.019","article-title":"A further investigation concerning correlation between anti-fibrotic effect of liposomal quercetin and inflammatory cytokines in pulmonary fibrosis","volume":"642","author":"Baowen","year":"2010","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib7","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1164\/rccm.201502-0299OC","article-title":"Membrane-anchored serine protease matriptase is a trigger of pulmonary fibrogenesis","volume":"193","author":"Bardou","year":"2016","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.jep.2016.12.042_bib8","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1183\/09059180.00001013","article-title":"Evidence-based treatment strategies in idiopathic pulmonary fibrosis","volume":"22","author":"Behr","year":"2013","journal-title":"Eur. Respir. Rev."},{"key":"10.1016\/j.jep.2016.12.042_bib9","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1002\/ptr.5622","article-title":"Antiinflammatory, antioxidant, and immunological effects of Crocus sativus L. and its main constituents","volume":"30","author":"Boskabady","year":"2016","journal-title":"Phytother. Res."},{"key":"10.1016\/j.jep.2016.12.042_bib10","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.phymed.2010.01.002","article-title":"Antiasthmatic effect of Nigella sativa in airways of asthmatic patients","volume":"17","author":"Boskabady","year":"2010","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2016.12.042_bib11","doi-asserted-by":"crossref","first-page":"e0155388","DOI":"10.1371\/journal.pone.0155388","article-title":"Retraction: innate immune activation by inhaled lipopolysaccharide, independent of oxidative stress, exacerbates silica-induced pulmonary fibrosis in mice","volume":"11","author":"Brass","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2016.12.042_bib12","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1080\/15548627.2015.1034409","article-title":"Essential role for the ATG4B protease and autophagy in bleomycin-induced pulmonary fibrosis","volume":"11","author":"Cabrera","year":"2015","journal-title":"Autophagy"},{"key":"10.1016\/j.jep.2016.12.042_bib13","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.jep.2016.04.018","article-title":"Characteristics of traditional Chinese medicine usage in patients with stroke in Taiwan: a nationwide population-based study","volume":"186","author":"Chang","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib14","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1183\/09031936.00152106","article-title":"Inhibition of PDGF, VEGF and FGF signalling attenuates fibrosis","volume":"29","author":"Chaudhary","year":"2007","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.jep.2016.12.042_bib15","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1080\/15384047.2016.1139229","article-title":"Triptolide mitigates radiation-induced pulmonary fibrosis via inhibition of axis of alveolar macrophages-NOXes-ROS-myofibroblasts","volume":"17","author":"Chen","year":"2016","journal-title":"Cancer Biol. Ther."},{"key":"10.1016\/j.jep.2016.12.042_bib16","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jep.2016.03.051","article-title":"Effect of Renshen Pingfei decoction, a traditional Chinese prescription, on IPF induced by bleomycin in rats and regulation of TGF-\u03b21\/Smad3","volume":"186","author":"Chen","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib17","first-page":"29","article-title":"Observation on clinical effect of andrographolide sulfonate nebulization in treating acute exacerbation of COPD","volume":"22","author":"Chen","year":"2013","journal-title":"China Pharm."},{"key":"10.1016\/j.jep.2016.12.042_bib18","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.fct.2013.04.024","article-title":"Protective effects of naringin against paraquat-induced acute lung injury and pulmonary fibrosis in mice","volume":"58","author":"Chen","year":"2013","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jep.2016.12.042_bib19","first-page":"103","article-title":"Study the efficacy of combine traditional Chinese and Western medicine to improve the quality life in patients with radiation-induced pulmonary fibrosis","volume":"12","author":"Cheng","year":"2015","journal-title":"Med. Innov. China"},{"key":"10.1016\/j.jep.2016.12.042_bib20","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s12931-015-0211-9","article-title":"Astragalin inhibits autophagy-associated airway epithelial fibrosis","volume":"16","author":"Cho","year":"2015","journal-title":"Respir. Res."},{"key":"10.1016\/j.jep.2016.12.042_bib21","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1165\/rcmb.2015-0020TR","article-title":"Matrix metalloproteinases as therapeutic targets for idiopathic pulmonary fibrosis","volume":"53","author":"Craig","year":"2015","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.jep.2016.12.042_bib22","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1007\/s00011-015-0878-x","article-title":"Total glycosides of Yupingfeng protects against bleomycin-induced pulmonary fibrosis in rats associated with reduced high mobility group box 1 activation and epithelial-mesenchymal transition","volume":"64","author":"Cui","year":"2015","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.jep.2016.12.042_bib23","doi-asserted-by":"crossref","first-page":"L442","DOI":"10.1152\/ajplung.00026.2010","article-title":"Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis","volume":"299","author":"Degryse","year":"2010","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"10.1016\/j.jep.2016.12.042_bib24","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.phrs.2015.04.012","article-title":"Bleomycin in the setting of lung fibrosis induction: from biological mechanisms to counteractions","volume":"97","author":"Della Latta","year":"2015","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.jep.2016.12.042_bib25","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.cbi.2016.01.006","article-title":"Celastrol enhances Nrf2 mediated antioxidant enzymes and exhibits anti-fibrotic effect through regulation of collagen production against bleomycin-induced pulmonary fibrosis","volume":"246","author":"Divya","year":"2016","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.jep.2016.12.042_bib26","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.intimp.2012.03.011","article-title":"Houttuynia cordata inhibits lipopolysaccharide-induced rapid pulmonary fibrosis by up-regulating IFN-\u03b3 and inhibiting the TGF-\u03b21\/Smad pathway","volume":"13","author":"Du","year":"2012","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib27","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.nutres.2014.09.005","article-title":"Resveratrol supplementation improves inflammatory biomarkers in patients with nonalcoholic fatty liver disease","volume":"34","author":"Faghihzadeh","year":"2014","journal-title":"Nutr. Res."},{"key":"10.1016\/j.jep.2016.12.042_bib28","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1111\/j.2042-7158.2012.01490.x","article-title":"Total glucosides of Danggui Buxue Tang attenuates bleomycin-induced pulmonary fibrosis via inhibition of extracellular matrix remodeling","volume":"64","author":"Gao","year":"2012","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib29","first-page":"1636","article-title":"Antiinflammatory and immunoregulatory effects of total glucosides of Yupingfeng powder","volume":"122","author":"Gao","year":"2009","journal-title":"Chin. Med. J."},{"key":"10.1016\/j.jep.2016.12.042_bib30","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jep.2011.03.013","article-title":"Antifibrosis effects of total glucosides of Danggui-Buxue-Tang in a rat model of bleomycin-induced pulmonary fibrosis","volume":"136","author":"Gao","year":"2011","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib31","doi-asserted-by":"crossref","first-page":"215","DOI":"10.3389\/fphar.2015.00215","article-title":"Glycyrrhizic acid alleviates bleomycin-induced pulmonary fibrosis in rats","volume":"6","author":"Gao","year":"2015","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib32","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.pupt.2013.03.006","article-title":"Baicalein attenuates bleomycin-induced pulmonary fibrosis in rats through inhibition of miR-21","volume":"26","author":"Gao","year":"2013","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.jep.2016.12.042_bib33","doi-asserted-by":"crossref","first-page":"238","DOI":"10.3390\/ijms17020238","article-title":"The Chinese herbal medicine formula mKG suppresses pulmonary fibrosis of mice induced by bleomycin","volume":"17","author":"Gao","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2016.12.042_bib34","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/j.jff.2015.06.032","article-title":"Anti-inflammatory, antioxidant, and immunomodulatory aspects of Nigella sativa for its preventive and bronchodilatory effects on obstructive respiratory diseases: a review of basic and clinical evidence","volume":"17","author":"Gholamnezhad","year":"2015","journal-title":"J. Funct. Foods"},{"key":"10.1016\/j.jep.2016.12.042_bib35","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.jep.2016.06.061","article-title":"Preclinical and clinical effects of Nigella sativa and its constituent, thymoquinone: a review","volume":"190","author":"Gholamnezhad","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib36","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.jep.2016.09.015","article-title":"Employing observational method for prospective data collection: a case study for analyzing diagnostic process and evaluating efficacy of TCM treatments for diabetes mellitus","volume":"192","author":"Gu","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib37","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1038\/nature07811","article-title":"Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease","volume":"458","author":"Gu","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.jep.2016.12.042_bib38","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.ejphar.2016.02.032","article-title":"Enhanced anti-tumor activity and reduced toxicity by combination andrographolide and bleomycin in ascitic tumor-bearing mice","volume":"776","author":"Guo","year":"2016","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib39","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1248\/bpb.b15-00358","article-title":"Osthole alleviates bleomycin-induced pulmonary fibrosis via modulating angiotensin-converting enzyme 2\/angiotensin-(1\u20137) axis and decreasing inflammation responses in rats","volume":"39","author":"Hao","year":"2016","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.jep.2016.12.042_bib40","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.phymed.2010.09.001","article-title":"In vivo anti-tumour activity of corilagin on Hep3B hepatocellular carcinoma","volume":"18","author":"Hau","year":"2010","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2016.12.042_bib41","doi-asserted-by":"crossref","first-page":"4190","DOI":"10.3892\/mmr.2015.3333","article-title":"Tanshinone IIA attenuates bleomycin-induced pulmonary fibrosis in rats","volume":"11","author":"He","year":"2015","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.jep.2016.12.042_bib42","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1080\/10408690390826464","article-title":"Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions","volume":"43","author":"Higdon","year":"2003","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.jep.2016.12.042_bib43","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1177\/1753465815586335","article-title":"The role of the NLRP3 inflammasome in pulmonary diseases","volume":"9","author":"Hosseinian","year":"2015","journal-title":"Ther. Adv. Respir. Dis."},{"key":"10.1016\/j.jep.2016.12.042_bib44","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1208\/s12248-014-9714-4","article-title":"Lipidomics revealed idiopathic pulmonary fibrosis-induced hepatic lipid disorders corrected with treatment of baicalin in a murine model","volume":"17","author":"Hu","year":"2015","journal-title":"AAPS J."},{"key":"10.1016\/j.jep.2016.12.042_bib45","doi-asserted-by":"crossref","first-page":"15282","DOI":"10.1038\/srep15282","article-title":"Hirsutella sinensis mycelium attenuates bleomycin-induced pulmonary inflammation and fibrosis in vivo","volume":"5","author":"Huang","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2016.12.042_bib46","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/nature03712","article-title":"Angiotensin-converting enzyme 2 protects from severe acute lung failure","volume":"436","author":"Imai","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.jep.2016.12.042_bib47","doi-asserted-by":"crossref","first-page":"846740","DOI":"10.1155\/2013\/846740","article-title":"Experimental and clinical pharmacology of andrographis paniculata and its major bioactive phytoconstituent andrographolide","volume":"2013","author":"Jayakumar","year":"2013","journal-title":"Evid. Based Complement. Altern. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib48","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.jep.2013.08.017","article-title":"Paeoniflorin, the main active constituent of Paeonia lactiflora roots, attenuates bleomycin-induced pulmonary fibrosis in mice by suppressing the synthesis of type I collagen","volume":"149","author":"Ji","year":"2013","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib49","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1038\/aps.2016.36","article-title":"Paeoniflorin suppresses TGF-\u03b2 mediated epithelial-mesenchymal transition in pulmonary fibrosis through a Smad-dependent pathway","volume":"37","author":"Ji","year":"2016","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.jep.2016.12.042_bib50","first-page":"883","article-title":"Clinical research of curcumin in the intervention treatment for pulmonary fibrosis induced by paraquat poisoning","volume":"21","author":"Jiang","year":"2015","journal-title":"Med. Recapitul."},{"key":"10.1016\/j.jep.2016.12.042_bib51","first-page":"1571","article-title":"Effects of triptolide on serum cytokine levels, symptoms and pulmonary function in patients with steroid-resistant asthma","volume":"22","author":"Jiang","year":"2006","journal-title":"Chin. J. Pathophysiol."},{"key":"10.1016\/j.jep.2016.12.042_bib52","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1016\/j.ijom.2015.06.015","article-title":"Allicin as a possible adjunctive therapeutic drug for stage II oral submucous fibrosis: a preliminary clinical trial in a Chinese cohort","volume":"44","author":"Jiang","year":"2015","journal-title":"Int. J. Oral. Maxillofac. Surg."},{"issue":"26","key":"10.1016\/j.jep.2016.12.042_bib53","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1517\/13543776.2016.1118060","article-title":"Pharmacological effects of berberine and its derivatives: a patent update","volume":"2016","author":"Jin","year":"2016","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.jep.2016.12.042_bib54","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.acthis.2008.10.008","article-title":"Effects of Nigella sativa seed extract on ameliorating lung tissue damage in rats after experimental pulmonary aspirations","volume":"111","author":"Kanter","year":"2009","journal-title":"Acta Histochem."},{"key":"10.1016\/j.jep.2016.12.042_bib55","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.biopha.2016.01.021","article-title":"Drug discovery of neurodegenerative disease through network pharmacology approach in herbs","volume":"78","author":"Ke","year":"2016","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2016.12.042_bib56","first-page":"939","article-title":"The relaxant effect of Nigella sativa on smooth muscles, its possible mechanisms and clinical applications","volume":"17","author":"Keyhanmanesh","year":"2014","journal-title":"Iran. J. Basic Med. Sci."},{"key":"10.1016\/j.jep.2016.12.042_bib57","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1056\/NEJMoa1402582","article-title":"A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis","volume":"370","author":"King","year":"2014","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib58","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1002\/jcp.22448","article-title":"Role of Smad2\/3 and p38 MAP kinase in TGF-\u03b21-induced epithelial-mesenchymal transition of pulmonary epithelial cells","volume":"226","author":"Kolosova","year":"2011","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.jep.2016.12.042_bib59","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1038\/nm1267","article-title":"A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury","volume":"11","author":"Kuba","year":"2005","journal-title":"Nat. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib60","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/j.tips.2016.06.009","article-title":"Transgenic mouse models transferred into the test tube: new perspectives for developmental toxicity testing in vitro?","volume":"37","author":"Kugler","year":"2016","journal-title":"Trends Pharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib61","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1093\/carcin\/bgp334","article-title":"Dietary quercetin, quercetin-gene interaction, metabolic gene expression in lung tissue and lung cancer risk","volume":"31","author":"Lam","year":"2010","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.jep.2016.12.042_bib62","doi-asserted-by":"crossref","first-page":"e000105","DOI":"10.1136\/bmjresp-2015-000105","article-title":"Safety of pirfenidone in patients with idiopathic pulmonary fibrosis: integrated analysis of cumulative data from 5 clinical trials","volume":"3","author":"Lancaster","year":"2016","journal-title":"BMJ Open Respir. Res."},{"key":"10.1016\/j.jep.2016.12.042_bib63","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1093\/jnci\/92.2.154","article-title":"Intake of flavonoids and lung cancer","volume":"92","author":"Le Marchand","year":"2000","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.jep.2016.12.042_bib64","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1667\/RR1522.1","article-title":"Dietary curcumin increases antioxidant defenses in lung, ameliorates radiation-induced pulmonary fibrosis, and improves survival in mice","volume":"173","author":"Lee","year":"2010","journal-title":"Radiat. Res."},{"key":"10.1016\/j.jep.2016.12.042_bib65","first-page":"65","article-title":"The effect observation of hydroxy safflor yellow A in the treatment of acute cerebral infarction","volume":"54","author":"Li","year":"2014","journal-title":"Shandong Med. J."},{"key":"10.1016\/j.jep.2016.12.042_bib66","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.phymed.2014.10.011","article-title":"Total extract of Yupingfeng attenuates bleomycin-induced pulmonary fibrosis in rats","volume":"22","author":"Li","year":"2015","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2016.12.042_bib67","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1111\/jcmm.12419","article-title":"Emerging role of HMGB1 in fibrotic diseases","volume":"18","author":"Li","year":"2014","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib68","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1124\/jpet.114.218370","article-title":"Functions of galectin-3 and its role in fibrotic diseases","volume":"351","author":"Li","year":"2014","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.jep.2016.12.042_bib69","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1124\/jpet.114.222372","article-title":"High-mobility group box 1 mediates epithelial-to-mesenchymal transition in pulmonary fibrosis involving transforming growth factor-b1\/Smad2\/3 signaling","volume":"354","author":"Li","year":"2015","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.jep.2016.12.042_bib70","article-title":"Large dose of fresh Eclipta prostrata in combination with a small amount of citrus reticulata Blanco peels in the treatment of 50 cases chronic bronchitis","volume":"45","author":"Li","year":"2004","journal-title":"J. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib71","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1142\/S0192415X06004417","article-title":"Symptom combinations associated with outcome and therapeutic effects in a cohort of cases with SARS","volume":"34","author":"Li","year":"2006","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib72","first-page":"29","article-title":"The clinical research of curative effect of Cordyceps sinensis extract combined with methylprednisolone on with idiopathic pulmonary fibrosis","volume":"37","author":"Li","year":"2015","journal-title":"Acta Acad. Med. Weifang"},{"key":"10.1016\/j.jep.2016.12.042_bib73","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.jep.2016.06.051","article-title":"Integrative traditional Chinese medicine therapy reduces the risk of diabetic ketoacidosis in patients with type 1 diabetes mellitus","volume":"191","author":"Lien","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib74","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0254-6272(14)60075-3","article-title":"Clinical observation of Eriobotrya japonica (Thunb.) Lindl. leaf drink in the treatment of the gastrointestinal side effects of middle-late stage lung cancer chemotherapy","volume":"34","author":"Lin","year":"2015","journal-title":"Shandong J. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib75","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s12989-016-0167-z","article-title":"Macrophage-derived MCPIP1 mediates silica-induced pulmonary fibrosis via autophagy","volume":"13","author":"Liu","year":"2016","journal-title":"Part. Fibre Toxicol."},{"key":"10.1016\/j.jep.2016.12.042_bib76","first-page":"815","article-title":"Oxymatrine attenuates bleomycin-induced pulmonary fibrosis in mice via the inhibition of inducible nitric oxide synthase expression and the TGF-\u03b2\/Smad signaling pathway","volume":"29","author":"Liu","year":"2012","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2016.12.042_bib77","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1016\/j.thromres.2014.07.019","article-title":"Salvianolic acid B inhibits platelets as a P2Y 12 antagonist and PDE inhibitor: evidence from clinic to laboratory","volume":"134","author":"Liu","year":"2014","journal-title":"Thromb. Res."},{"key":"10.1016\/j.jep.2016.12.042_bib78","first-page":"2531","article-title":"Effects of resveratrol on the lung functions, serum TNF-\u03b1 and IL-8 in women patients with chronic obstructive pulmonary disease","volume":"36","author":"Liu","year":"2015","journal-title":"Guangdong Med. J."},{"key":"10.1016\/j.jep.2016.12.042_bib79","doi-asserted-by":"crossref","first-page":"961","DOI":"10.3736\/jcim20101008","article-title":"Effects of Chinese herbal medicine Shenlong Decoction on mRNA expressions of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 in lung tissue of rats with pulmonary fibrosis induced by bleomycin","volume":"8","author":"Lu","year":"2010","journal-title":"Zhong Xi Yi Jie He Xue Bao"},{"key":"10.1016\/j.jep.2016.12.042_bib80","first-page":"177","article-title":"Effect of Runfei decoction on radiation pneumonitis and radioactive pulmonary fibrosis of patients with lung cancer","volume":"29","author":"Mei","year":"2014","journal-title":"China J. Chin. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib81","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.lungcan.2010.04.014","article-title":"The safety and efficacy of weekly paclitaxel in combination with carboplatin for advanced non-small cell lung cancer with idiopathic interstitial pneumonias","volume":"71","author":"Minegishi","year":"2011","journal-title":"Lung Cancer"},{"key":"10.1016\/j.jep.2016.12.042_bib82","first-page":"415","article-title":"Therapeutic effects of glycyrrhizic acid","volume":"8","author":"Ming","year":"2013","journal-title":"Nat. Prod. Commun."},{"key":"10.1016\/j.jep.2016.12.042_bib83","doi-asserted-by":"crossref","first-page":"L152","DOI":"10.1152\/ajplung.00313.2007","article-title":"Murine models of pulmonary fibrosis","volume":"294","author":"Moore","year":"2008","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"10.1016\/j.jep.2016.12.042_bib84","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1097\/MCP.0b013e328349ac2b","article-title":"Modeling pulmonary fibrosis with bleomycin","volume":"17","author":"Mouratis","year":"2011","journal-title":"Curr. Opin. Pulm. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib85","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.bcp.2015.07.002","article-title":"Unknown unknowns in biomedical research: does an inability to deal with ambiguity contribute to issues of irreproducibility?","volume":"97","author":"Mullane","year":"2015","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib86","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.bcp.2015.06.023","article-title":"Guidelines for manuscript submission in the peer-reviewed pharmacological literature","volume":"97","author":"Mullane","year":"2015","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib87","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.pharep.2015.03.012","article-title":"Protective effect of gallic acid against bleomycin-induced pulmonary fibrosis in rats","volume":"67","author":"Nikbakht","year":"2015","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.jep.2016.12.042_bib88","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.ejphar.2013.06.004","article-title":"Protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice","volume":"714","author":"Niu","year":"2013","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib89","first-page":"137","article-title":"Clinical efficiency of tanshinone IIA-sulfonate in treatment of liver fibrosis of advanced schistosomiasis","volume":"25","author":"Niu","year":"2013","journal-title":"Chin. J. Schisto. Control"},{"key":"10.1016\/j.jep.2016.12.042_bib90","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1007\/s12325-011-0068-3","article-title":"The \u201cMESACA\u201d study: methylsulfonylmethane and boswellic acids in the treatment of gonarthrosis","volume":"28","author":"Notarnicola","year":"2011","journal-title":"Adv. Ther."},{"key":"10.1016\/j.jep.2016.12.042_bib91","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1016\/j.jep.2014.07.049","article-title":"Prevention of pulmonary fibrosis with salvianolic acid a by inducing fibroblast cell cycle arrest and promoting apoptosis","volume":"155","author":"Pan","year":"2014","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib92","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1183\/09031936.00114311","article-title":"Pirfenidone treatment in idiopathic pulmonary fibrosis: too much of a great expectation?","volume":"40","author":"Papiris","year":"2012","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.jep.2016.12.042_bib93","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1016\/j.phytochem.2008.01.027","article-title":"Cordyceps: a traditional Chinese medicine and another fungal therapeutic biofactory?","volume":"69","author":"Paterson","year":"2008","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jep.2016.12.042_bib94","first-page":"695","article-title":"Protectant effect of quercetin on the expression of matrix metalloproteinases in human embryonic lung fibroblasts in vitro","volume":"32","author":"Peng","year":"2013","journal-title":"Her. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib95","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.phrs.2016.06.018","article-title":"Network pharmacology of cancer: from understanding of complex interactomes to the design of multi-target specific therapeutics from nature","volume":"111","author":"Poornima","year":"2016","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.jep.2016.12.042_bib96","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1111\/imj.13078","article-title":"Idiopathic pulmonary fibrosis: an Australian perspective","volume":"46","author":"Prasad","year":"2016","journal-title":"Intern. Med. J."},{"key":"10.1016\/j.jep.2016.12.042_bib97","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1038\/aps.2016.53","article-title":"Identification of the anti-tumor activity and mechanisms of nuciferine through a network pharmacology approach","volume":"37","author":"Qi","year":"2016","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.jep.2016.12.042_bib98","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.phymed.2016.01.011","article-title":"Protective role of gambogic acid in experimental pulmonary fibrosis in vitro and in vivo","volume":"23","author":"Qu","year":"2016","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2016.12.042_bib99","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1164\/rccm.200602-163OC","article-title":"Incidence and prevalence of idiopathic pulmonary fibrosis","volume":"174","author":"Raghu","year":"2006","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.jep.2016.12.042_bib100","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.tox.2006.09.005","article-title":"Preventive effect of naringin on lipid peroxides and antioxidants in isoproterenol-induced cardiotoxicity in Wistar rats: biochemical and histopathological evidences","volume":"228","author":"Rajadurai","year":"2006","journal-title":"Toxicology"},{"key":"10.1016\/j.jep.2016.12.042_bib101","doi-asserted-by":"crossref","first-page":"254","DOI":"10.3389\/fphar.2015.00254","article-title":"MicroRNAs as potential targets for progressive pulmonary fibrosis","volume":"6","author":"Rajasekaran","year":"2015","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib102","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.pupt.2016.07.009","article-title":"Pirfenidone, nintedanib and N-acetylcysteine for the treatment of idiopathic pulmonary fibrosis: a systematic review and meta-analysis","volume":"40","author":"Rogliani","year":"2016","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.jep.2016.12.042_bib103","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1183\/09031936.00182412","article-title":"Ex vivo micro-computed tomography analysis of bleomycin-induced lung fibrosis for preclinical drug evaluation","volume":"42","author":"Scotton","year":"2013","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.jep.2016.12.042_bib104","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1093\/jac\/dkh174","article-title":"Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis","volume":"53","author":"Shadkchan","year":"2004","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.jep.2016.12.042_bib105","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.jep.2015.10.017","article-title":"A review of the relaxant effect of various medicinal plants on tracheal smooth muscle, their possible mechanism(s) and potency","volume":"175","author":"Shakeri","year":"2015","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib106","first-page":"237","article-title":"Effects of neferine on platelet aggregation in patients with hyperlipidemias and healthy subjects","volume":"14","author":"Shi","year":"1998","journal-title":"Chin. Pharmacol. Bull."},{"key":"10.1016\/j.jep.2016.12.042_bib107","first-page":"433","article-title":"Gastrointestinal symptoms in idiopathic pulmonary fibrosis patients treated with pirfenidone and herbal medicine","volume":"28","author":"Shimizu","year":"2013","journal-title":"J. Biol. Regul. Homeost. Agents"},{"key":"10.1016\/j.jep.2016.12.042_bib108","doi-asserted-by":"crossref","first-page":"L616","DOI":"10.1152\/ajplung.00002.2009","article-title":"Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury","volume":"298","author":"Smith","year":"2010","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"10.1016\/j.jep.2016.12.042_bib109","doi-asserted-by":"crossref","first-page":"221","DOI":"10.3177\/jnsv.49.221","article-title":"Gallic acid, an antioxidant, exhibits antiapoptotic potential in normal human lymphocytes: a Bcl-2 independent mechanism","volume":"49","author":"Sohi","year":"2003","journal-title":"J. Nutr. Sci. Vitaminol."},{"key":"10.1016\/j.jep.2016.12.042_bib110","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s11655-013-1442-6","article-title":"Anti-inflammatory and immunoregulatory effects of Yupingfeng powder on chronic bronchitis rats","volume":"19","author":"Song","year":"2013","journal-title":"Chin. J. Integr. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib111","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.pupt.2008.12.010","article-title":"Epigallocatechin-3-gallate augments antioxidant activities and inhibits inflammation during bleomycin-induced experimental pulmonary fibrosis through Nrf2-Keap1 signaling","volume":"22","author":"Sriram","year":"2009","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.jep.2016.12.042_bib112","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.cbi.2009.02.017","article-title":"Epigallocatechin-3-gallate exhibits anti-fibrotic effect by attenuating bleomycin-induced glycoconjugates, lysosomal hydrolases and ultrastructural changes in rat model pulmonary fibrosis","volume":"180","author":"Sriram","year":"2009","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.jep.2016.12.042_bib113","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1111\/1440-1681.12428","article-title":"Epigallocatechin gallate attenuates fibroblast proliferation and excessive collagen production by effectively intervening TGF-\u03b21 signalling","volume":"42","author":"Sriram","year":"2015","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.jep.2016.12.042_bib114","first-page":"46","article-title":"Efficacy and safety of safflower yellow sodium chloride injection combined with methylprednisolone in treatment of patients with idiopathic pulmonary fibrosis","volume":"20","author":"Sun","year":"2016","journal-title":"J. Clin. Med. Pract."},{"key":"10.1016\/j.jep.2016.12.042_bib115","first-page":"209","article-title":"Interference of Tonifying Qi, activating blood and dispersing accumulation on pulmonary fibrosis and the mechanism research","volume":"27","author":"Sun","year":"2008","journal-title":"J. Tianjin Univ. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib116","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s12192-015-0654-4","article-title":"Salidroside protects against bleomycin-induced pulmonary fibrosis: activation of Nrf2-antioxidant signaling, and inhibition of NF-\u03baB and TGF-\u03b21\/Smad-2\/-3 pathways","volume":"21","author":"Tang","year":"2016","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.jep.2016.12.042_bib117","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1142\/S0192415X88000212","article-title":"Effects of Qing-Fei-Tang (Seihai-to) and baicalein, its main component flavonoid, on lucigenin-dependent chemiluminescence and leukotriene-dependence chemiluminescence and leukotriene B4 synthesis of human alveolar macrophages","volume":"16","author":"Tanno","year":"1988","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib118","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1056\/NEJMe1601193","article-title":"Treatment of malaria in pregnancy","volume":"374","author":"Tarning","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib119","first-page":"127","article-title":"Effect of Qingre Huoxue Sanjie Chinese medicine compound on serum cytokines IL-6, TNF-\u03b1, TGF-\u03b21 level of radiation pneumonitis and pulmonary fibrosis patients","volume":"20","author":"Tian","year":"2014","journal-title":"Chin. J. Exp. Tradit. Med. Formulae"},{"key":"10.1016\/j.jep.2016.12.042_bib120","doi-asserted-by":"crossref","first-page":"7601393","DOI":"10.1155\/2016\/7601393","article-title":"The protective effect of naringin against bleomycin-induced pulmonary fibrosis in Wistar rats","volume":"2016","author":"Turgut","year":"2016","journal-title":"Pulm. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib121","doi-asserted-by":"crossref","first-page":"e70725","DOI":"10.1371\/journal.pone.0070725","article-title":"Low-dose paclitaxel ameliorates pulmonary fibrosis by suppressing TGF-\u03b21\/Smad3 pathway via mir-140 upregulation","volume":"8","author":"Wang","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2016.12.042_bib122","first-page":"182","article-title":"Curative effect of Yangyin Yiqi formula in treating pulmonary fibrosis","volume":"35","author":"Wang","year":"2014","journal-title":"Shaanxi J. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib123","first-page":"641","article-title":"Effects of glycyrrhizic acid diamine on serum hyaluronic acid and procollagen III in patients with idiopathic pulmonary interstitial fibrosis","volume":"20","author":"Wang","year":"2012","journal-title":"Pract. J. Card. Cereb. Pneumal Vasc. Dis."},{"key":"10.1016\/j.jep.2016.12.042_bib124","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1248\/bpb.34.511","article-title":"Inhibitory effect of safflor yellow on pulmonary fibrosis","volume":"34","author":"Wang","year":"2011","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.jep.2016.12.042_bib125","first-page":"1112","article-title":"Twenty-eight cases of silicosis combined with cor pulmonale treated with salvia miltiorrhiza polyphenols acid salt","volume":"6","author":"Wang","year":"2016","journal-title":"Henan Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib126","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1002\/med.20077","article-title":"New developments in the chemistry and biology of the bioactive constituents of tanshen","volume":"27","author":"Wang","year":"2007","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.jep.2016.12.042_bib127","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1248\/bpb.b14-00198","article-title":"Hydroxysafflor yellow A attenuates small airway remodeling in a rat model of chronic obstructive pulmonary disease","volume":"37","author":"Wang","year":"2014","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.jep.2016.12.042_bib128","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.antiviral.2011.01.005","article-title":"Oxymatrine inhibits hepatitis B infection with an advantage of overcoming drug-resistance","volume":"89","author":"Wang","year":"2011","journal-title":"Antivir. Res."},{"key":"10.1016\/j.jep.2016.12.042_bib129","doi-asserted-by":"crossref","first-page":"9762","DOI":"10.3390\/ijms15069762","article-title":"Corilagin attenuates aerosol bleomycin-induced experimental lung injury","volume":"15","author":"Wang","year":"2014","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2016.12.042_bib130","first-page":"733","article-title":"Anetwork pharmacology approach to discover active compounds and action mechanisms of San-Cao granule for treatment of liver fibrosis","volume":"10","author":"Wei","year":"2016","journal-title":"Drug Des. Dev. Ther."},{"key":"10.1016\/j.jep.2016.12.042_bib131","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1164\/rccm.201505-0862OC","article-title":"Plasma surfactant protein-D, matrix metalloproteinase-7, and osteopontin index distinguishes idiopathic pulmonary fibrosis from other idiopathic interstitial pneumonias","volume":"194","author":"White","year":"2016","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.jep.2016.12.042_bib132","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1124\/jpet.113.208223","article-title":"Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis","volume":"349","author":"Wollin","year":"2014","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.jep.2016.12.042_bib133","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1183\/09031936.00174914","article-title":"Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis","volume":"45","author":"Wollin","year":"2015","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.jep.2016.12.042_bib134","first-page":"40","article-title":"Clinical research of Qingjin decoction in treating idiopathic pulmonary fibrosis","volume":"24","author":"Wong","year":"2011","journal-title":"Gansu J. TCM"},{"key":"10.1016\/j.jep.2016.12.042_bib135","doi-asserted-by":"crossref","first-page":"578","DOI":"10.7150\/ijms.8365","article-title":"Tanshinone IIA attenuates bleomycin-induced pulmonary fibrosis via modulating angiotensin-converting enzyme 2\/ angiotensin-(1-7) axis in rats","volume":"11","author":"Wu","year":"2014","journal-title":"Int. J. Med. Sci."},{"key":"10.1016\/j.jep.2016.12.042_bib136","first-page":"118","article-title":"Clinical observation of Bufei Huoxue decoction in treating idiopathic pulmonary fibrosis","volume":"29","author":"Wu","year":"2010","journal-title":"Beijing J. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib137","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1055\/s-2005-837821","article-title":"Inhibitory effects of isoliensinine on bleomycin-induced pulmonary fibrosis in mice","volume":"71","author":"Xiao","year":"2005","journal-title":"Planta Med."},{"key":"10.1016\/j.jep.2016.12.042_bib138","first-page":"151","article-title":"Effects of tanshinone IIA-sulfonate on C-reactive protein and procalcitonin in patients with severe pneumonia","volume":"20","author":"Xiao","year":"2016","journal-title":"J. Clin. Med. Pract."},{"key":"10.1016\/j.jep.2016.12.042_bib139","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1111\/jphp.12308","article-title":"Total polysaccharide of Yupingfeng protects against bleomycin-induced pulmonary fibrosis via inhibiting transforming growth factor-\u03b21-mediated type I collagen abnormal deposition in rats","volume":"66","author":"Xu","year":"2014","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib140","first-page":"183","article-title":"Clinical observation of peony liquorice decoction in treating patients with advanced cancer","volume":"18","author":"Xu","year":"2016","journal-title":"J. Liaoning Univ. TCM"},{"key":"10.1016\/j.jep.2016.12.042_bib141","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1248\/bpb.33.1438","article-title":"The ethical Kampo formulation Sho-seiryu-to (TJ-19) prevents bleomycin-induced pulmonary fibrosis in rats","volume":"33","author":"Yang","year":"2010","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.jep.2016.12.042_bib142","article-title":"A clinical study on treating idiopathic pulmonary fibrosis with Dazhu Hongjingtian injection","volume":"6","author":"Yang","year":"2014","journal-title":"Clin. J. Chin. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib143","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1111\/j.1440-1843.2009.01644.x","article-title":"How useful is traditional herbal medicine for pulmonary fibrosis?","volume":"14","author":"Yang","year":"2009","journal-title":"Respirology"},{"key":"10.1016\/j.jep.2016.12.042_bib144","first-page":"35","article-title":"Clinical observation on the effect of Jade screen powder associated with hormone in the treatment of radiation-induced pulmonary fibrosis","volume":"9","author":"Yang","year":"2012","journal-title":"China Med. Her."},{"key":"10.1016\/j.jep.2016.12.042_bib145","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1111\/j.2042-7158.2012.01550.x","article-title":"Antifibrosis effects of triterpene acids of Eriobotrya japonica (Thunb.) Lindl. leaf in a rat model of bleomycin-induced pulmonary fibrosis","volume":"64","author":"Yang","year":"2012","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib146","doi-asserted-by":"crossref","first-page":"92","DOI":"10.3892\/ijmm.2014.1745","article-title":"The green tea extract epigallocatechin-3-gallate inhibits irradiation-induced pulmonary fibrosis in adult rats","volume":"34","author":"You","year":"2014","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib147","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.jep.2015.08.034","article-title":"Preventive effects of Ecliptae Herba extract and its component, ecliptasaponin A, on bleomycin-induced pulmonary fibrosis in mice","volume":"175","author":"You","year":"2015","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib148","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.lfs.2016.03.056","article-title":"Tetrahydropalmatine attenuates irradiation induced lung injuries in rats","volume":"153","author":"Yu","year":"2016","journal-title":"Life Sci."},{"key":"10.1016\/j.jep.2016.12.042_bib149","first-page":"1269","article-title":"Clinical research of Huqi Huoxue decoction in treating idiopathic pulmonary fibrosis","volume":"29","author":"Zhang","year":"2014","journal-title":"China J. Chin. Med."},{"key":"10.1016\/j.jep.2016.12.042_bib150","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2165\/11632530-000000000-00000","article-title":"Protective effects of salidroside on epirubicin-induced early left ventricular regional systolic dysfunction in patients with breast cancer","volume":"12","author":"Zhang","year":"2012","journal-title":"Drugs R. D."},{"key":"10.1016\/j.jep.2016.12.042_bib151","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.jep.2010.06.022","article-title":"Tectorigenin inhibits the in vitro proliferation and enhances miR-338* expression of pulmonary fibroblasts in rats with idiopathic pulmonary fibrosis","volume":"131","author":"Zhang","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib152","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.jep.2006.08.016","article-title":"Therapeutic effect of Chinese medicine formula DSQRL on experimental pulmonary fibrosis","volume":"109","author":"Zhang","year":"2007","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib153","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.jep.2007.11.039","article-title":"Chinese medicine formula DSQRL versus glucocorticoids for the treatment of experimental pulmonary fibrosis","volume":"116","author":"Zhang","year":"2008","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib154","doi-asserted-by":"crossref","first-page":"172","DOI":"10.3109\/01902148.2014.895070","article-title":"The inhibitory effect of salvianolic acid B on TGF-\u03b21-induced proliferation and differentiation in lung fibroblasts","volume":"40","author":"Zhang","year":"2014","journal-title":"Exp. Lung Res."},{"key":"10.1016\/j.jep.2016.12.042_bib155","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jep.2016.05.025","article-title":"Traditional Chinese medicine formulas for the treatment of osteoporosis: implication for antiosteoporotic drug discovery","volume":"189","author":"Zhang","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib156","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.clnu.2014.08.014","article-title":"Resveratrol ameliorates lipopolysaccharide-induced epithelial mesenchymal transition and pulmonary fibrosis through suppression of oxidative stress and transforming growth factor-\u03b21 signaling","volume":"34","author":"Zhang","year":"2015","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.jep.2016.12.042_bib157","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.radonc.2015.02.014","article-title":"A prospective phase II trial of EGCG in treatment of acute radiation-induced esophagitis for stage III lung cancer","volume":"114","author":"Zhao","year":"2015","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.jep.2016.12.042_bib158","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.ejphar.2009.11.007","article-title":"Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis","volume":"627","author":"Zhao","year":"2010","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib159","doi-asserted-by":"crossref","first-page":"645814","DOI":"10.1155\/2015\/645814","article-title":"Total glucosides of danggui buxue tang attenuate BLM-induced pulmonary fibrosis via regulating oxidative stress by inhibiting NOX4","volume":"2015","author":"Zhao","year":"2015","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.jep.2016.12.042_bib160","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.pharmthera.2016.02.004","article-title":"Effect of Liuwei Dihuang decoction, a traditional Chinese medicinal prescription, on the neuroendocrine immunomodulation network","volume":"162","author":"Zhou","year":"2016","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.jep.2016.12.042_bib161","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.jep.2006.11.029","article-title":"Inhibitory effects of Hu-qi-yin on the bleomycin-induced pulmonary fibrosis in rats","volume":"111","author":"Zhou","year":"2007","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib162","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4238\/gmr.15027309","article-title":"Atomized paclitaxel liposome inhalation treatment of bleomycin-induced pulmonary fibrosis in rats","volume":"15","author":"Zhou","year":"2016","journal-title":"Genet. Mol. Res."},{"key":"10.1016\/j.jep.2016.12.042_bib163","doi-asserted-by":"crossref","first-page":"430","DOI":"10.3389\/fphar.2016.00430","article-title":"Induced pluripotent stem cells inhibit bleomycin-induced pulmonary fibrosis in mice through suppressing TGF-\u03b21\/Smad-mediated epithelial to mesenchymal transition","volume":"7","author":"Zhou","year":"2016","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2016.12.042_bib164","first-page":"79","article-title":"Phase I human tolerability trial of gambogic acid","volume":"16","author":"Zhou","year":"2007","journal-title":"Chin. J. New Drugs"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116308029?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116308029?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T13:50:35Z","timestamp":1536155435000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874116308029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":164,"alternative-id":["S0378874116308029"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2016.12.042","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Traditional Chinese medicine for pulmonary fibrosis therapy: Progress and future prospects","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2016.12.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}