{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T21:35:56Z","timestamp":1793136956316,"version":"4.5.0"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002641","name":"Konkuk University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002641","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1016\/j.jep.2017.03.043","type":"journal-article","created":{"date-parts":[[2017,3,24]],"date-time":"2017-03-24T13:34:15Z","timestamp":1490362455000},"page":"173-177","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"special_numbering":"C","title":["Protective effects of Cinnamomum cassia (Lamaceae) against gout and septic responses via attenuation of inflammasome activation in experimental models"],"prefix":"10.1016","volume":"205","author":[{"given":"Woo-Young","family":"Shin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Do-Wan","family":"Shim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myong-Ki","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sushruta","family":"Koppula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang\u2013Hyeun","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han-Bi","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tack-Joong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae-Bong","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang-Ho","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2017.03.043_bib1","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1177\/09680519990050030401","article-title":"Anti-endotoxin properties of a cinnamon bark-derived compound and its effect on the endotoxin shock model","volume":"5","author":"Azumi","year":"1999","journal-title":"J. Endotoxin Res."},{"key":"10.1016\/j.jep.2017.03.043_bib2","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1006\/bbrc.1997.6668","article-title":"A novel inhibitor of bacterial endotoxin derived from cinnamon bark","volume":"234","author":"Azumi","year":"1997","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jep.2017.03.043_bib3","doi-asserted-by":"crossref","first-page":"380","DOI":"10.3109\/09637486.2011.627849","article-title":"Bioactivity of cinnamon with special on diabetes mellitus: a review","volume":"63","author":"Bandara","year":"2012","journal-title":"Int. J. Food Sci. Nutr."},{"issue":"3","key":"10.1016\/j.jep.2017.03.043_bib4","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/nm.3806","article-title":"A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases","volume":"21","author":"Coll","year":"2015","journal-title":"Nat. Med."},{"issue":"9","key":"10.1016\/j.jep.2017.03.043_bib5","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1038\/sj.cdd.4402194","article-title":"The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation","volume":"14","author":"Fernandes-Alnemri","year":"2007","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.jep.2017.03.043_bib6","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/ni.1703","article-title":"The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis","volume":"10","author":"Franchi","year":"2009","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.jep.2017.03.043_bib7","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jep.2016.05.059","article-title":"Juniperus rigida Sieb. extract inhibits inflammatory responses via attenuation of TRIF-dependent signaling and inflammasome activation","volume":"190","author":"Han","year":"2016","journal-title":"J. Ethnopharmacol."},{"issue":"12","key":"10.1016\/j.jep.2017.03.043_bib8","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1038\/ni.2749","article-title":"Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity","volume":"14","author":"Hara","year":"2013","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.jep.2017.03.043_bib9","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1016\/j.foodchem.2012.12.020","article-title":"Inhibition of neuroinflammation by cinnamon and its main components","volume":"138","author":"Ho","year":"2013","journal-title":"Food Chem."},{"key":"10.1016\/j.jep.2017.03.043_bib10","doi-asserted-by":"crossref","first-page":"9792","DOI":"10.1074\/jbc.M109.082305","article-title":"Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome","volume":"285","author":"Juliana","year":"2010","journal-title":"J. Biol. Chem."},{"issue":"7371","key":"10.1016\/j.jep.2017.03.043_bib11","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/nature10558","article-title":"Non-canonical inflammasome activation targets caspase-11","volume":"479","author":"Kayagaki","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.jep.2017.03.043_bib12","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jep.2005.08.059","article-title":"Anti-diabetic effect of cinnamon extract on blood glucose in db\/db mice","volume":"104","author":"Kim","year":"2006","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2017.03.043_bib13","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/nature04515","article-title":"Cryopyrin activates the inflammasome in response to toxins and ATP","volume":"440","author":"Mariathasan","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.jep.2017.03.043_bib14","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1038\/nature04516","article-title":"Gout-associated uric acid crystals activate the NALP3 inflammasome","volume":"440","author":"Martinon","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.jep.2017.03.043_bib15","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.ejim.2010.03.005","article-title":"Targeting IL-1\u03b2 in disease; the expanding role of NLRP3 inflammasome","volume":"21","author":"Mitroulis","year":"2010","journal-title":"Eur. J. Intern. Med."},{"key":"10.1016\/j.jep.2017.03.043_bib16","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1084\/jem.20132486","article-title":"The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation","volume":"211","author":"Rodgers","year":"2014","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jep.2017.03.043_bib17","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jep.2015.05.001","article-title":"Anti-inflammatory effect of Impatiens textori Miq. extract via inhibition of NLRP3 inflammasome activation in in vitro and in vivo experimental models","volume":"170","author":"Sun","year":"2015","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2017.03.043_bib18","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.jep.2010.10.043","article-title":"Inhibitory effects of Cinnamomum cassia extract on atopic dermatitis-like skin lesions induced by mite antigen in NC\/Nga mice","volume":"133","author":"Sung","year":"2011","journal-title":"J. Ethnopharmacol."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116322784?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874116322784?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T01:10:40Z","timestamp":1568941840000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874116322784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":18,"alternative-id":["S0378874116322784"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2017.03.043","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Protective effects of Cinnamomum cassia (Lamaceae) against gout and septic responses via attenuation of inflammasome activation in experimental models","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2017.03.043","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Ireland Ltd.","name":"copyright","label":"Copyright"}]}}