{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T21:40:21Z","timestamp":1761946821957,"version":"3.37.3"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21662004"],"award-info":[{"award-number":["21662004"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Open Research Fund program","award":["CMEMR2018\u2013C17"],"award-info":[{"award-number":["CMEMR2018\u2013C17"]}]},{"name":"Changjiang Scholars and Innovative Research Team","award":["IRT1225"],"award-info":[{"award-number":["IRT1225"]}]},{"name":"Department of Education Foundation of Guangxi Province","award":["2017KY0779"],"award-info":[{"award-number":["2017KY0779"]}]},{"DOI":"10.13039\/501100004607","name":"Natural Science Foundation of Guangxi Province","doi-asserted-by":"publisher","award":["2017GXNSFBA1980083"],"award-info":[{"award-number":["2017GXNSFBA1980083"]}],"id":[{"id":"10.13039\/501100004607","id-type":"DOI","asserted-by":"publisher"}]},{"name":"The Foundation of Key disciplines of universities in Guangxi Province","award":["2017KLOG16"],"award-info":[{"award-number":["2017KLOG16"]}]},{"name":"Innovation Project of Guangxi Graduate Education","award":["YCSW2018092"],"award-info":[{"award-number":["YCSW2018092"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.jep.2018.11.002","type":"journal-article","created":{"date-parts":[[2018,11,14]],"date-time":"2018-11-14T03:26:01Z","timestamp":1542165961000},"page":"170-178","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Discovery of anti-inflammatory terpenoids from Mallotus conspurcatus croizat"],"prefix":"10.1016","volume":"231","author":[{"given":"Yanjun","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xishan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huangcan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dexiong","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhengmin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ke","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengping","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruiyun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruijie","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2018.11.002_bib1","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/S0031-9422(00)89736-8","article-title":"Erythoxan diterpenes from fagonia species","volume":"36","author":"Abdel-Kader","year":"1997","journal-title":"Phytochmistry"},{"key":"10.1016\/j.jep.2018.11.002_bib2","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.2165\/00003495-200565160-00002","article-title":"Biologic therapy for inflammatory bowel disease","volume":"65","author":"Ardizzone","year":"2005","journal-title":"Drugs"},{"key":"10.1016\/j.jep.2018.11.002_bib3","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1002\/1097-458X(200007)38:7<488::AID-MRC704>3.0.CO;2-G","article-title":"Assignment of 1H and 13C spectra and investigation of hindered side-chain rotation in lupeol derivatives","volume":"38","author":"Burns","year":"2000","journal-title":"Magn. Reson. Chem."},{"key":"10.1016\/j.jep.2018.11.002_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1021\/np50115a001","article-title":"Isolation and structural elucidation of pentacyclic triterpenoids from Maprounea Africana","volume":"58","author":"Chaudhuri","year":"1995","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.jep.2018.11.002_bib5","first-page":"248","article-title":"Research progress on chemical constituents of plants from Mallotus Lour. and their pharmacological activities","volume":"45","author":"Chen","year":"2014","journal-title":"Chin. Tradit. Herbal Drugs"},{"key":"10.1016\/j.jep.2018.11.002_bib6","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1021\/acs.jafc.5b05931","article-title":"Anti-inflammatory cerebrosides from cultivated Cordyceps militaris","volume":"64","author":"Chiu","year":"2016","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jep.2018.11.002_bib7","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.arr.2008.07.002","article-title":"Molecular inflammation: underpinnings of aging and age-related diseases","volume":"8","author":"Chung","year":"2009","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.jep.2018.11.002_bib8","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.cellimm.2012.12.007","article-title":"The regulatory effect of veratric acid on NO production in LPS-stimulated RAW264.7 macrophage cells","volume":"280","author":"Choi","year":"2012","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.jep.2018.11.002_bib9","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1107\/S0021889808042726","article-title":"OLEX2: a complete structure solution, refinement and analysis program","volume":"42","author":"Dolomanov","year":"2009","journal-title":"J. Appl. Cryst."},{"key":"10.1016\/j.jep.2018.11.002_bib10","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1365-2249.2006.03261.x","article-title":"Chronic inflammation: importance of NOD2 and NALP3 in interleukin\u20101\u03b2 generation","volume":"147","author":"Ferrero-Miliani","year":"2007","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.jep.2018.11.002_bib11","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/S0031-9422(97)00312-9","article-title":"Terpenoids and flavonoids from Salvia cyanescens","volume":"46","author":"Gokdil","year":"1997","journal-title":"Phytochemistry"},{"unstructured":"Guangxi instituent of Botany and Acedemia Sinica editorial committee for Flora of Guangxi. 2005. Flora of Guangxi, Guangxi, Science and Technology Press, 2, 263\u2212275.","key":"10.1016\/j.jep.2018.11.002_bib12"},{"key":"10.1016\/j.jep.2018.11.002_bib13","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.jep.2018.02.031","article-title":"Anti-inflammatory action of Athyrium multidentatum extract suppresses the LPS-induced TLR4 signaling pathway","volume":"217","author":"Han","year":"2018","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2018.11.002_bib14","first-page":"20","article-title":"Progress on anti-inflammatory natural products","volume":"33","author":"Hou","year":"2015","journal-title":"J. Pharm. Pract."},{"key":"10.1016\/j.jep.2018.11.002_bib15","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1039\/C5MD00577A","article-title":"Design, synthesis and anti-inflammatory effects of novel 9-O-substituted-berberine derivatives","volume":"7","author":"Huang","year":"2016","journal-title":"Med. Chem. Comm."},{"unstructured":"Jacquot, D., Poeschke, O., Christa, B., 2011. New terpenes and macrocycles. US2011\/0092582 A1, Apr. 21.","key":"10.1016\/j.jep.2018.11.002_bib16"},{"key":"10.1016\/j.jep.2018.11.002_bib17","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1007\/s12272-001-1274-6","article-title":"Chemical constituents from the flower of Datura metel L","volume":"31","author":"Kuang","year":"2008","journal-title":"Arch. Pharm. Res."},{"key":"10.1016\/j.jep.2018.11.002_bib18","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.fitote.2015.07.015","article-title":"Paeoveitols A-E from Paeonia veitchii","volume":"106","author":"Liang","year":"2015","journal-title":"Fitoterapia"},{"key":"10.1016\/j.jep.2018.11.002_bib19","doi-asserted-by":"crossref","first-page":"107","DOI":"10.4196\/kjpp.2012.16.2.107","article-title":"3,4,5-trihydroxycinnamic acid inhibits LPS-induced iNOS expression by suppressing NF-\u03baB activation in BV2 microglial cells","volume":"16","author":"Lee","year":"2012","journal-title":"Korean J. Physiol. Pharmacol."},{"key":"10.1016\/j.jep.2018.11.002_bib20","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1021\/np400241p","article-title":"Ent-labdane diterpenes from the stems of mallotus japonicus","volume":"76","author":"Li","year":"2013","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.jep.2018.11.002_bib21","first-page":"273","article-title":"Triterpenoids from the stems of Casearia velutina Bl","volume":"21","author":"Li","year":"2012","journal-title":"J. Chin. Pharm. Sci."},{"key":"10.1016\/j.jep.2018.11.002_bib22","first-page":"599","article-title":"Research progress on chemical constituents and pharmacological activities of Mallotus apelta","volume":"35","author":"Li","year":"2013","journal-title":"Chin. Tradit. Pat. Med."},{"unstructured":"Liu, D.K., Zhang, J.X., Zhang, F.H., Wang, L.H., 2017, A kind of reflux esophageal anti-inflammatory drug. CN106860728, Jun 20.","key":"10.1016\/j.jep.2018.11.002_bib23"},{"key":"10.1016\/j.jep.2018.11.002_bib24","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1002\/hlca.200900059","article-title":"Germacrane\u2212type sesquiterpenes from Curcuma wenyujin","volume":"92","author":"Lou","year":"2009","journal-title":"Helv. Chim. Acta"},{"key":"10.1016\/j.jep.2018.11.002_bib25","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1159\/000212751","article-title":"Chemoprevention with phytochemicals targeting inducible nitric oxide synthase","volume":"61","author":"Murakami","year":"2009","journal-title":"Forum Nutr."},{"key":"10.1016\/j.jep.2018.11.002_bib26","first-page":"86","article-title":"Discusses the progress of Yao medicine","volume":"8","author":"Pang","year":"2017","journal-title":"Pop. Sci. Tech."},{"key":"10.1016\/j.jep.2018.11.002_bib27","doi-asserted-by":"crossref","first-page":"850","DOI":"10.3390\/molecules14020850","article-title":"Bioactive metabolites from Spilanthes acmella Murr","volume":"14","author":"Prachayasittikul","year":"2009","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2018.11.002_bib28","series-title":"A Checklish of Vascular Plants of Guangxi","first-page":"165","author":"Qin","year":"2010"},{"key":"10.1016\/j.jep.2018.11.002_bib29","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1107\/S0108767307043930","article-title":"A short history of SHELX","volume":"A64","author":"Sheldrick","year":"2008","journal-title":"Acta Cryst."},{"key":"10.1016\/j.jep.2018.11.002_bib30","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/s10787-007-0013-x","article-title":"Role of nitric oxide in inflammatory diseases","volume":"15","author":"Sharma","year":"2007","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.jep.2018.11.002_bib31","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1142\/S0192415X14500566","article-title":"Anti-inflammatory effect of Lycii radicis in LPS-stimulated RAW 264.7 macrophages","volume":"42","author":"Song","year":"2014","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.jep.2018.11.002_bib32","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.bse.2005.03.010","article-title":"Triterpenes from Angelica cartilagino\u2013marginata var. foliata Yuan et Shan and their significance as chemosystematic characters","volume":"33","author":"Sun","year":"2005","journal-title":"Biochem. Syst. Ecol."},{"key":"10.1016\/j.jep.2018.11.002_bib33","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1073\/pnas.91.6.2046","article-title":"Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation","volume":"91","author":"Vane","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jep.2018.11.002_bib34","first-page":"611","article-title":"Diterpenoids from Euphorbia wallichii","volume":"35","author":"Wang","year":"2004","journal-title":"Chin. Tradit. Herb. Drugs"},{"unstructured":"Wang, Z.P., Feng, Q., Liang, C., Li, F., 2017. Treatment of chronic pelvic inflammatory disease resistance disease sequelae of Zhuang medicine preparation and preparation method thereof, CN 107050359, Aug 18.","key":"10.1016\/j.jep.2018.11.002_bib35"},{"key":"10.1016\/j.jep.2018.11.002_bib36","first-page":"4501","article-title":"Isolation and chemotaxonomic significance of megastigmane-type sesquiterpenoids from Sarcandra glabra","volume":"6","author":"Wu","year":"2012","journal-title":"J. Med. Plants Res."},{"key":"10.1016\/j.jep.2018.11.002_bib37","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0031-9422(88)80621-6","article-title":"3\u03b2-(3,4-Dihydroxycinnamoyl)-erythrodiol and 3\u03b2-(4-hydroxycinna-moyl)-erythrodiol from Larrea tridentate","volume":"27","author":"Xue","year":"1988","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jep.2018.11.002_bib38","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.jep.2015.11.020","article-title":"Xanthii Fructus inhibits inflammatory responses in LPS stimulated RAW 264.7 macrophages through suppressing NF-\u03baB and JNK\/p38 MAPK","volume":"176","author":"Yeom","year":"2015","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2018.11.002_bib39","first-page":"333","article-title":"Research progress on chemical constituents of plants from Mallotus Lour","volume":"23","author":"Zhang","year":"1988","journal-title":"Chin. Pharm. Bull."},{"key":"10.1016\/j.jep.2018.11.002_bib40","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jep.2017.08.034","article-title":"Anti-inflammatory sesquiterpenoids from the traditional Chinese medicine Salvia plebeia: regulates pro-inflammatory mediators through inhibition of NF-\u03baB and Erk1\/2 signaling pathways in LPS-induced Raw264.7 cells","volume":"210","author":"Zou","year":"2018","journal-title":"J. Ethnopharmacol."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874118316039?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874118316039?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T22:54:04Z","timestamp":1662418444000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874118316039"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":40,"alternative-id":["S0378874118316039"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2018.11.002","relation":{},"ISSN":["0378-8741"],"issn-type":[{"type":"print","value":"0378-8741"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Discovery of anti-inflammatory terpenoids from Mallotus conspurcatus croizat","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2018.11.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}