{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T16:35:32Z","timestamp":1782491732986,"version":"3.54.5"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100004457","name":"TWAS","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004457","id-type":"DOI","asserted-by":"publisher"}]},{"name":"ICCBS"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1016\/j.jep.2019.02.026","type":"journal-article","created":{"date-parts":[[2019,2,13]],"date-time":"2019-02-13T11:51:05Z","timestamp":1550058665000},"page":"42-49","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Acute and sub-acute toxicity of the aqueous extract from the stem bark of Tetrapleura tetrapteura Taub. (Fabaceae) in mice and rats"],"prefix":"10.1016","volume":"236","author":[{"given":"Olivette Laure Matafack","family":"Dongmo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine Joissy","family":"Epoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herve Tchoumbou","family":"Tadjoua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sammer","family":"Yousuf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phelix Bruno","family":"Telefo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leon Azefack","family":"Tapondjou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Iqbal","family":"Choudhary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2019.02.026_bib1","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.jep.2005.11.027","article-title":"Preliminary toxicity and phytochemical studies of the stem bark of aqueous extract of Musanga cecropioides in rats","volume":"105","author":"Adeneye","year":"2006","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2019.02.026_bib2","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3389\/fphar.2014.00078","article-title":"Dose and time-dependent sub-chronic toxicity study of hydroethanolic leaf extract of Flabellaria paniculata Cav. (Malpighiaceae) in rodents","volume":"5","author":"Akindele","year":"2014","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2019.02.026_bib3","first-page":"23","article-title":"Tetrapleura tetraptera: molluscicidal activity and chemical constituents: a review","volume":"4","author":"Aladesammi","year":"2007","journal-title":"Afr. J. Trad. Complement. Altern. Med"},{"issue":"3","key":"10.1016\/j.jep.2019.02.026_bib4","first-page":"1196","article-title":"Screening for hypoglycemic activity on the leaf extracts of nine medicinal plants: In-vivo evaluation","volume":"9","author":"Arya","year":"2012","journal-title":"Eur.-J. Chem."},{"issue":"9","key":"10.1016\/j.jep.2019.02.026_bib5","first-page":"397","article-title":"Aqueous extract of Tetrapleura tetraptera (Mimosaceae) prevents hypertension, dyslipidemia and oxidative stress in high salt-sucrose induced hypertensive rats","volume":"3","author":"Bella","year":"2012","journal-title":"Res. Gate"},{"key":"10.1016\/j.jep.2019.02.026_bib6","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.amjmed.2003.10.036","article-title":"Commonly used herbal medicines in the United States: a review","volume":"116","author":"Bent","year":"2004","journal-title":"Am. J. Med."},{"key":"10.1016\/j.jep.2019.02.026_bib7","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1038\/ja.2008.16","article-title":"Microbial drug discovery: 80 years of progress","volume":"62","author":"Demain","year":"2009","journal-title":"J. Antibiot."},{"issue":"4","key":"10.1016\/j.jep.2019.02.026_bib8","first-page":"57","article-title":"Effect of aqueous extract of Tetrapleura tetraptera on excision wounds in albino rats","volume":"5","author":"Effiong","year":"2014","journal-title":"Int. Res. J."},{"key":"10.1016\/j.jep.2019.02.026_bib9","doi-asserted-by":"crossref","first-page":"177","DOI":"10.3389\/fphar.2013.00177","article-title":"The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety","volume":"4","author":"Ekor","year":"2014","journal-title":"Front Pharmacol."},{"issue":"1","key":"10.1016\/j.jep.2019.02.026_bib10","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jep.2003.11.009","article-title":"Acute and chronic toxicological studies of Ajuga iva in experimental animals","volume":"91","author":"El Hilaly","year":"2004","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2019.02.026_bib11","article-title":"Biochemical and histological studies of aqueous extract of Bidens pilosa leaves from Ugandan Rift Valley in rats","volume":"2","author":"Ezeonwumelu","year":"2011","journal-title":"Br. J. Pharmacol. Toxicol."},{"key":"10.1016\/j.jep.2019.02.026_bib12","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.jep.2010.07.013","article-title":"Acute toxicity study of the standardized methanolic extract of Mitragyna speciosa Korth in rodent","volume":"131","author":"Harizal","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2019.02.026_bib13","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.jep.2004.06.026","article-title":"Anti-inflammatory and hypoglycaemic effects of Tetrapleura tetraptera (Taub) [fabaceae] fruit aqueous extract in rats","volume":"95","author":"John","year":"2004","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2019.02.026_bib14","first-page":"13","article-title":"Tetrapleura tetraptera spice attenuates high-carbohydrate, high-fat diet-induced obese and type 2 diabetic rats with metabolic syndrome features","author":"Kuate","year":"2015","journal-title":"Lip Health Dis."},{"issue":"2","key":"10.1016\/j.jep.2019.02.026_bib15","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.jsps.2011.01.003","article-title":"Analgesic, anti-inflammatory, antipyretic and toxicological evaluation of some newer 3-methyl pyrazolone derivatives","volume":"19","author":"Mariappan","year":"2011","journal-title":"Saudi Pharm. J."},{"key":"10.1016\/j.jep.2019.02.026_bib16","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1080\/109158101317097728","article-title":"Gender-based differences in the toxicity of pharmaceuticals-the food and drug administration's perspective","volume":"20","author":"Miller","year":"2001","journal-title":"Int. J. Toxicol."},{"key":"10.1016\/j.jep.2019.02.026_bib17","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.tips.2009.12.001","article-title":"Gender differences in drug toxicity","volume":"3","author":"Nicolson","year":"2010","journal-title":"Trends Pharmacol. Sci."},{"issue":"6","key":"10.1016\/j.jep.2019.02.026_bib18","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.apjtb.2016.04.001","article-title":"Preliminary studies of acute and sub-chronic toxicity of the aqueous extract of Guibourtia tessmannii (Harms) J. Leonard stem barks (Caesalpiniaceae) in mice and rats","volume":"6","author":"Noreen","year":"2016","journal-title":"Asian Pac. J. Trop. Biomed."},{"key":"10.1016\/j.jep.2019.02.026_bib19","series-title":"Guide-line for Testing of Chemical: 425 Acute Oral Toxicity: Up-and-Down Procedure","author":"OECD","year":"2008"},{"key":"10.1016\/j.jep.2019.02.026_bib20","series-title":"Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents","author":"OECD","year":"2008"},{"key":"10.1016\/j.jep.2019.02.026_bib21","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1055\/s-2007-969824","article-title":"Cardiovascular and neuromuscular actions of scopotein from fruit of Tetrapleura tetrapteura","volume":"49","author":"Ojewole","year":"1983","journal-title":"Planta Med."},{"issue":"9","key":"10.1016\/j.jep.2019.02.026_bib22","first-page":"303","article-title":"Reduction of platelet and lymphocyte counts and elevation of neutrophil counts in rats treated with aqueous leaf extract of Ocimum gratissimum. Afr","volume":"5","author":"Okon","year":"2011","journal-title":"J. Biochem. Res."},{"issue":"1","key":"10.1016\/j.jep.2019.02.026_bib23","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.cll.2010.10.004","article-title":"Preclinical safety assessment: current gaps, challenges, and approaches in identifying translatable biomarkers of drug-induced liver injury","volume":"31","author":"Ramaiah","year":"2011","journal-title":"Clin. Lab Med."},{"key":"10.1016\/j.jep.2019.02.026_bib24","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1080\/01926230701595300","article-title":"Society of toxicologic pathology position paper: organ weight recommendations for toxicology studies","volume":"35","author":"Rani","year":"2007","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.jep.2019.02.026_bib25","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.fitote.2010.02.001","article-title":"Herbal drugs: standards and regulation","volume":"81","author":"Sahoo","year":"2010","journal-title":"Fitoterapia"},{"issue":"1","key":"10.1016\/j.jep.2019.02.026_bib26","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1128\/CMR.00032-07","article-title":"Molecular pathogenesis of Shigella spp.: controlling host cell signaling, invasion, and death by type III secretion","volume":"21","author":"Schroeder","year":"2008","journal-title":"Clin. Microb. Rev."},{"issue":"1","key":"10.1016\/j.jep.2019.02.026_bib27","first-page":"13","article-title":"Acute and subacute toxicological assessment of the leaf aqueous extract of Eremomastax speciosa (Acanthaceae) in wistar rats","volume":"4","author":"Siwe","year":"2015","journal-title":"J. Adv. Med. Pharma Sc."},{"issue":"6","key":"10.1016\/j.jep.2019.02.026_bib28","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.thromres.2005.12.011","article-title":"Aqueous extracts of Ocimum basilicum L.(sweet basil) decrease platelet aggregation induced by ADP and thrombin in vitro and rats arterio\u2013venous shunt thrombosis In vivo","volume":"118","author":"Tohti","year":"2006","journal-title":"Thromb. Res."},{"key":"10.1016\/j.jep.2019.02.026_bib29","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.fct.2016.09.018","article-title":"Oral acute and subchronic toxicity studies of the oil extracted from pequi (Caryocar brasiliense, Camb.) pulp in rats","volume":"97","author":"Traesel","year":"2016","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jep.2019.02.026_bib30","first-page":"58","article-title":"Toxicological studies of aqueous root extract of Euphorbia lateriflora (Schum and Thonn) in rats","author":"Usman","year":"2014","journal-title":"J. Med. Plants Stud."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874118332057?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874118332057?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T14:43:04Z","timestamp":1565188984000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874118332057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":30,"alternative-id":["S0378874118332057"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2019.02.026","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acute and sub-acute toxicity of the aqueous extract from the stem bark of Tetrapleura tetrapteura Taub. (Fabaceae) in mice and rats","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2019.02.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}