{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:43:46Z","timestamp":1786992226903,"version":"build-2736575974"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100014768","name":"College Student Research and Training Project of Jiaxing University","doi-asserted-by":"publisher","award":["CD8517193190"],"award-info":[{"award-number":["CD8517193190"]}],"id":[{"id":"10.13039\/501100014768","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014768","name":"Scientific Research Foundation of Jiaxing University","doi-asserted-by":"publisher","award":["CD70519024"],"award-info":[{"award-number":["CD70519024"]}],"id":[{"id":"10.13039\/501100014768","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81603317"],"award-info":[{"award-number":["81603317"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Sichuan Science and Technology Program","award":["2018JY0179"],"award-info":[{"award-number":["2018JY0179"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1016\/j.jep.2020.112813","type":"journal-article","created":{"date-parts":[[2020,4,4]],"date-time":"2020-04-04T18:49:54Z","timestamp":1586026194000},"page":"112813","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Lignans from Schisandra chinensis ameliorate alcohol and CCl4-induced long-term liver injury and reduce hepatocellular degeneration via blocking ETBR"],"prefix":"10.1016","volume":"258","author":[{"given":"Jin-Biao","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang-Chun","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Jing","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Yu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Xin","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Miao","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Ming","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2020.112813_bib1","doi-asserted-by":"crossref","first-page":"8168","DOI":"10.1021\/acs.jmedchem.5b01781","article-title":"Endothelin-receptor antagonists beyond pulmonary arterial hypertension: cancer and fibrosis","volume":"59","author":"Aubert","year":"2016","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.jep.2020.112813_bib2","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.freeradbiomed.2013.06.023","article-title":"Signaling pathways involved in isoprostane-mediated fibrogenic effects in rat hepatic stellate cells","volume":"65","author":"Acquaviva","year":"2013","journal-title":"Free Radic. Biol. Med."},{"issue":"8","key":"10.1016\/j.jep.2020.112813_bib3","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.4103\/jfmpc.jfmpc_439_19","article-title":"Personal or family history of metabolic traits predispose to higher hepatotoxic effects of alcohol","volume":"8","author":"Bhadoria","year":"2019","journal-title":"J.\u00a0Fam. Med. Prim. Care"},{"key":"10.1016\/j.jep.2020.112813_bib4","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1038\/ng.3417","article-title":"A\u00a0genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis","volume":"47","author":"Buch","year":"2015","journal-title":"Nat. Genet."},{"issue":"6","key":"10.1016\/j.jep.2020.112813_bib5","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1002\/hep.22592","article-title":"Ethanol and arachidonic acid synergize to activate Kupffer cells and modulate the fibrogenic response via tumor necrosis factor alpha, reduced glutathione, and transforming growth factor beta-dependent mechanisms","volume":"48","author":"Cubero","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.jep.2020.112813_bib6","author":"Cambridge Soft"},{"issue":"2","key":"10.1016\/j.jep.2020.112813_bib7","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1124\/pr.115.011833","volume":"68","author":"Davenport","year":"2016","journal-title":"Endothelin. Pharmacol. Rev."},{"issue":"5","key":"10.1016\/j.jep.2020.112813_bib8","first-page":"272","article-title":"Endothelin receptor inhibition with bosentan delays onset of liver injury in streptozotocin-induced diabetic condition","volume":"65","author":"Demirci","year":"2015","journal-title":"Drug Res."},{"key":"10.1016\/j.jep.2020.112813_bib9","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1021\/np200937h","article-title":"Dibenzocyclooctadiene lignans from Kadsura polysperma and their antineurodegenerative activities","volume":"75","author":"Dong","year":"2012","journal-title":"J.\u00a0Nat. Prod."},{"key":"10.1016\/j.jep.2020.112813_bib10","doi-asserted-by":"crossref","first-page":"357","DOI":"10.3389\/fonc.2018.00357","article-title":"Transforming growth factor-\u03b2-induced cell plasticity in liver fibrosis and hepatocarcinogenesis","volume":"8","author":"Fabregat","year":"2018","journal-title":"Front. Oncol."},{"issue":"10","key":"10.1016\/j.jep.2020.112813_bib11","doi-asserted-by":"crossref","first-page":"8071","DOI":"10.18632\/oncotarget.3513","article-title":"Systems biology network-based discovery of a small molecule activator BL-AD008 targeting AMPK\/ZIPK and inducing apoptosis in cervical cancer","volume":"6","author":"Fu","year":"2015","journal-title":"Oncotarget"},{"issue":"2","key":"10.1016\/j.jep.2020.112813_bib12","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.lfs.2014.04.021","article-title":"Endothelin-1 and its role in the pathogenesis of infectious diseases","volume":"118","author":"Freeman","year":"2014","journal-title":"Life Sci."},{"key":"10.1016\/j.jep.2020.112813_bib13","doi-asserted-by":"crossref","DOI":"10.1111\/jgh.12036","article-title":"Epidemiology of alcoholic and nonalcoholic fatty liver disease in China","author":"Fan","year":"2013","journal-title":"J.\u00a0Gastroenterol. Hepatol."},{"key":"10.1016\/j.jep.2020.112813_bib14","article-title":"A\u00a0schistosome miRNA promotes host hepatic fibrosis by targeting transforming growth factor beta receptor III","author":"He","year":"2019","journal-title":"J.\u00a0Hepatol."},{"key":"10.1016\/j.jep.2020.112813_bib15","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.phytochem.2014.04.014","article-title":"Dibenzocyclooctadiene lignans from Schisandra chinensis and their inhibitory activity on NO production in lipopolysaccharide-activated microglia cells","volume":"104","author":"Hu","year":"2014","journal-title":"Phytochemistry"},{"issue":"2","key":"10.1016\/j.jep.2020.112813_bib16","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1254\/jphs.13R02CR","article-title":"Endothelin receptor signaling: new insight into its regulatory mechanisms","volume":"123","author":"Horinouchi","year":"2013","journal-title":"J.\u00a0Pharmacol. Sci."},{"issue":"6","key":"10.1016\/j.jep.2020.112813_bib17","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1600-0773.1996.tb00228.x","article-title":"Effect of a lignan-enriched extract of Schisandra chinensis on aflatoxin B1 and cadmium chloride-induced hepatotoxicity in rats","volume":"78","author":"Ip","year":"1996","journal-title":"Pharmacol. Toxicol."},{"key":"10.1016\/j.jep.2020.112813_bib18","doi-asserted-by":"crossref","DOI":"10.1021\/acs.molpharmaceut.9b00737","article-title":"Ultrastable and biofunctionalizable conjugated polymer nanoparticles with encapsulated iron for ferroptosis assisted chemodynamic therapy","author":"Jasim","year":"2019","journal-title":"Mol. Pharm."},{"issue":"3","key":"10.1016\/j.jep.2020.112813_bib19","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/aps.2015.120","article-title":"Schisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2\/ARE signaling pathway","volume":"37","author":"Jiang","year":"2016","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.jep.2020.112813_bib20","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.cbi.2015.02.022","article-title":"Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation","volume":"231","author":"Jiang","year":"2015","journal-title":"Chem. Biol. Interact."},{"issue":"2","key":"10.1016\/j.jep.2020.112813_bib21","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.stemcr.2017.06.010","article-title":"An in vitro human liver model by iPSC-derived parenchymal and non-parenchymal cells","volume":"9","author":"Koui","year":"2017","journal-title":"Stem Cell Reports"},{"issue":"1","key":"10.1016\/j.jep.2020.112813_bib22","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1053\/j.gastro.2015.09.039","article-title":"Endoplasmic reticulum stress in hepatic stellate cells promotes liver fibrosis via PERK-mediated degradation of HNRNPA1 and up-regulation of SMAD2","volume":"150","author":"Koo","year":"2016","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jep.2020.112813_bib23","article-title":"Adiponectin agonist ADP355 attenuates CCl4-induced liver fibrosis in mice","author":"Kumar","year":"2014","journal-title":"PloS One"},{"issue":"2","key":"10.1016\/j.jep.2020.112813_bib24","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.jep.2011.03.037","article-title":"The lignan-rich fractions of Fructus Schisandrae improve insulin sensitivity via the PPAR-\u03b3 pathways in in vitro and in vivo studies","volume":"135","author":"Kwon","year":"2011","journal-title":"J.\u00a0Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.jep.2020.112813_bib25","first-page":"4","article-title":"Endothelin receptors and pain","volume":"10","author":"Khodorova","year":"2009","journal-title":"J.\u00a0Pain"},{"issue":"3","key":"10.1016\/j.jep.2020.112813_bib26","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1097\/01.shk.0000196549.18258.6a","article-title":"Inhibition of endothelin-1-mediated up-regulation of iNOS by bosentan ameliorates endotoxin-induced liver injury in cirrhosis","volume":"25","author":"Keller","year":"2006","journal-title":"Shock"},{"issue":"6","key":"10.1016\/j.jep.2020.112813_bib27","doi-asserted-by":"crossref","first-page":"351","DOI":"10.2165\/00044011-200626060-00006","article-title":"Montelukast decreases plasma endothelin-1 and serum eosinophil cationic protein levels in paediatric atopic asthma","volume":"26","author":"Kopriva","year":"2006","journal-title":"Clin. Drug Invest."},{"issue":"8","key":"10.1016\/j.jep.2020.112813_bib28","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1053\/j.gastro.2016.02.043","article-title":"Alcoholic liver disease in asia, europe, and north America","volume":"150","author":"Liangpunsakul","year":"2016","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.jep.2020.112813_bib29","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s12013-014-0266-0","article-title":"Effects of triterpenoid from Schisandra chinensis on oxidative stress in alcohol-induced liver injury in rats","volume":"71","author":"Li","year":"2015","journal-title":"Cell Biochem. Biophys."},{"issue":"4","key":"10.1016\/j.jep.2020.112813_bib30","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/nrgastro.2015.35","article-title":"Alcoholic liver disease: mechanisms of injury and targeted treatment","volume":"12","author":"Louvet","year":"2015","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"6","key":"10.1016\/j.jep.2020.112813_bib31","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1111\/acer.12424","article-title":"Modulation of fatty acid and bile acid metabolism by peroxisome proliferator-activated receptor \u03b1 protects against alcoholic liver disease","volume":"38","author":"Li","year":"2014","journal-title":"Alcohol Clin. Exp. Res."},{"issue":"3","key":"10.1016\/j.jep.2020.112813_bib32","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1111\/jgh.12425","article-title":"Schisandrin B attenuates acetaminophen-induced hepatic injury through heat-shock protein 27 and 70 in mice","volume":"29","author":"Li","year":"2014","journal-title":"J.\u00a0Gastroenterol. Hepatol."},{"key":"10.1016\/j.jep.2020.112813_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhep.2015.03.006","article-title":"Trends in the management and burden of alcoholic liver disease","author":"Mathurin","year":"2015","journal-title":"J.\u00a0Hepatol."},{"issue":"3","key":"10.1016\/j.jep.2020.112813_bib34","doi-asserted-by":"crossref","first-page":"332","DOI":"10.15252\/emmm.201404246","article-title":"Hepatic stellate cell-expressed endosialin balances fibrogenesis and hepatocyte proliferation during liver damage","volume":"7","author":"Mogler","year":"2015","journal-title":"EMBO Mol. Med."},{"issue":"40","key":"10.1016\/j.jep.2020.112813_bib35","doi-asserted-by":"crossref","first-page":"14787","DOI":"10.3748\/wjg.v20.i40.14787","article-title":"Review of natural products with hepatoprotective effects","volume":"20","author":"Madrigal-Santill\u00e1n","year":"2014","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.jep.2020.112813_bib36","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0102009","article-title":"Amelioration of cold injury-induced cortical brain edema formation by selective endothelin ETB receptor antagonists in mice","author":"Michinaga","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.jep.2020.112813_bib37","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.yjmcc.2013.05.021","article-title":"Intracrine endothelin signaling evokes IP3-dependent increases in nucleoplasmic Ca2+ in adult cardiac myocytes","volume":"62","author":"Merlen","year":"2013","journal-title":"J.\u00a0Mol. Cell. Cardiol."},{"issue":"4","key":"10.1016\/j.jep.2020.112813_bib38","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.jhep.2010.11.005","article-title":"Endoplasmic reticulum stress in liver disease","volume":"54","author":"Malhi","year":"2011","journal-title":"J.\u00a0Hepatol."},{"key":"10.1016\/j.jep.2020.112813_bib39","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1002\/cbdv.200790087","article-title":"Dibenzocyclooctane lignans from the stems of Kadsura induta and their antiviral effect on hepatitis B virus","volume":"4","author":"Ma","year":"2007","journal-title":"Chem. Biodivers."},{"issue":"3","key":"10.1016\/j.jep.2020.112813_bib40","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1097\/01.mog.0000218961.86182.8c","article-title":"Hepatocellular carcinoma","volume":"22","author":"Marrero","year":"2006","journal-title":"Curr. Opin. Gastroenterol."},{"key":"10.1016\/j.jep.2020.112813_bib41","series-title":"Pharmacopoeia of People's Republic of China","first-page":"66","author":"National Pharmacopoeia Committee","year":"2015"},{"issue":"9","key":"10.1016\/j.jep.2020.112813_bib42","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.3748\/wjg.v20.i9.2136","article-title":"Role of mitochondria in alcoholic liver disease","volume":"20","author":"Nassir","year":"2014","journal-title":"World J. Gastroenterol."},{"issue":"5","key":"10.1016\/j.jep.2020.112813_bib43","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1002\/hep.29051","article-title":"An endoplasmic reticulum protein, Nogo-B, facilitates alcoholic liver disease through regulation of kupffer cell polarization","volume":"65","author":"Park","year":"2017","journal-title":"Hepatology"},{"issue":"7620","key":"10.1016\/j.jep.2020.112813_bib44","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1038\/nature19319","article-title":"Activation mechanism of endothelin ETB receptor by endothelin-1","volume":"537","author":"Shihoya","year":"2016","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.jep.2020.112813_bib45","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1002\/jhbp.245","article-title":"Recent advancement of molecular mechanisms of liver fibrosis","volume":"22","author":"Seki","year":"2015","journal-title":"J.\u00a0Hepatobiliary Pancreat. Sci."},{"issue":"2","key":"10.1016\/j.jep.2020.112813_bib46","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.jhep.2013.09.013","article-title":"A\u00a0novel mouse model of depletion of stellate cells clarifies their role in ischemia\/reperfusion- and endotoxin-induced acute liver injury","volume":"60","author":"Stewart","year":"2014","journal-title":"J.\u00a0Hepatol."},{"issue":"1","key":"10.1016\/j.jep.2020.112813_bib47","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1172\/JCI114962","article-title":"Endothelin action in rat liver. Receptors, free Ca2+ oscillations, and activation of glycogenolysis","volume":"87","author":"Serradeil-Le Gal","year":"1991","journal-title":"J.\u00a0Clin. Invest."},{"issue":"17","key":"10.1016\/j.jep.2020.112813_bib48","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1056\/NEJMoa1412278","article-title":"Prednisolone or pentoxifylline for alcoholic hepatitis","volume":"372","author":"Thursz","year":"2015","journal-title":"N.\u00a0Engl. J. Med."},{"issue":"1","key":"10.1016\/j.jep.2020.112813_bib49","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jep.2010.11.070","article-title":"The protective effect of Schisandra lignans on stress-evoked hepatic metastases of P815 tumor cells in restraint mice","volume":"134","author":"Tang","year":"2011","journal-title":"J.\u00a0Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.jep.2020.112813_bib50","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s12011-014-0105-6","article-title":"Oxidative stress and Ca2+ signals involved on cadmium-induced apoptosis in rat hepatocyte","volume":"161","author":"Wang","year":"2014","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.jep.2020.112813_bib51","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.ejphar.2014.01.022","article-title":"Protective effect of Et-1 receptor antagonist bosentan on paracetamol induced acute liver toxicity in rats","volume":"726","author":"Yayla","year":"2014","journal-title":"Eur. J. Pharmacol."},{"issue":"10","key":"10.1016\/j.jep.2020.112813_bib52","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1002\/cbin.11021","article-title":"LncRNA Gm5091 alleviates alcoholic hepatic fibrosis by sponging miR-27b\/23b\/24 in mice","volume":"42","author":"Zhou","year":"2018","journal-title":"Cell Biol. Int."},{"key":"10.1016\/j.jep.2020.112813_bib53","doi-asserted-by":"crossref","first-page":"9947","DOI":"10.3390\/ijms14059947","article-title":"Molecular dynamics simulation of tryptophan hydroxylase-1: binding modes and free energy analysis to phenylalanine derivative inhibitors","volume":"13","author":"Zhong","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2020.112813_bib54","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.1016\/j.phytochem.2011.08.014","article-title":"Identification of GABA A receptor modulators in Kadsura longipedunculata and assignment of absolute configurations by quantum-chemical ECD calculations","volume":"72","author":"Zaugg","year":"2011","journal-title":"Phytochemistry"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874119352018?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874119352018?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T16:33:00Z","timestamp":1759941180000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874119352018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":54,"alternative-id":["S0378874119352018"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2020.112813","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lignans from Schisandra chinensis ameliorate alcohol and CCl4-induced long-term liver injury and reduce hepatocellular degeneration via blocking ETBR","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2020.112813","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"112813"}}