{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T22:27:16Z","timestamp":1793053636403,"version":"4.5.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010618","name":"Guangzhou University of Chinese Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010618","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010883","name":"Traditional Chinese Medicine Bureau of Guangdong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010883","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.jep.2021.113789","type":"journal-article","created":{"date-parts":[[2021,1,8]],"date-time":"2021-01-08T18:40:12Z","timestamp":1610131212000},"page":"113789","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"special_numbering":"C","title":["Zihuai recipe alleviates cyclophosphamide-induced diminished ovarian reserve via suppressing PI3K\/AKT-mediated apoptosis"],"prefix":"10.1016","volume":"277","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2338-7514","authenticated-orcid":false,"given":"Weiping","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5960-0826","authenticated-orcid":false,"given":"Qi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhidan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwei","family":"Weng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Truong Nam","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaming","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaohu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2021.113789_bib1","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.steroids.2004.09.005","article-title":"Licorice reduces serum testosterone in healthy women","volume":"69","author":"Armanini","year":"2004","journal-title":"Steroids"},{"key":"10.1016\/j.jep.2021.113789_bib2","first-page":"1","article-title":"Cyclophosphamide, a cancer chemotherapy drug-induced early onset of reproductive senescence and alterations in reproductive performance and their prevention in mice","author":"Athira","year":"2020","journal-title":"Drug Chem. Toxicol."},{"key":"10.1016\/j.jep.2021.113789_bib3","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1007\/s43032-020-00191-w","article-title":"Diminished ovarian reserve chemotherapy-induced mouse model: a tool for the preclinical assessment of new therapies for ovarian damage","volume":"27","author":"Buigues","year":"2019","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.jep.2021.113789_bib4","doi-asserted-by":"crossref","first-page":"602","DOI":"10.3390\/medicina55090602","article-title":"The controversial history of hormone replacement therapy","volume":"55","author":"Cagnacci","year":"2019","journal-title":"Medicina"},{"key":"10.1016\/j.jep.2021.113789_bib5","doi-asserted-by":"crossref","first-page":"836","DOI":"10.3390\/ijms17060836","article-title":"Follicle loss and apoptosis in cyclophosphamide-treated mice: what's the matter?","volume":"17","author":"Chen","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2021.113789_bib6","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1055\/s-0032-1306301","article-title":"Hormonal regulation of female reproduction","volume":"44","author":"Christensen","year":"2012","journal-title":"Horm. Metab. Res."},{"key":"10.1016\/j.jep.2021.113789_bib7","doi-asserted-by":"crossref","first-page":"573","DOI":"10.3390\/medicina55090573","article-title":"Current evidence of the oncological benefit-risk profile of hormone replacement therapy","volume":"55","author":"D'Alonzo","year":"2019","journal-title":"Medicina"},{"key":"10.1016\/j.jep.2021.113789_bib8","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.fertnstert.2015.05.017","article-title":"Diminished ovarian reserve in the United States assisted reproductive technology population: diagnostic trends among 181,536 cycles from the Society for Assisted Reproductive Technology Clinic Outcomes Reporting System","volume":"104","author":"Devine","year":"2015","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jep.2021.113789_bib9","doi-asserted-by":"crossref","first-page":"D45","DOI":"10.1530\/EJE-19-0373","article-title":"AMH as the primary marker for fertility","volume":"181","author":"Dewailly","year":"2019","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.jep.2021.113789_bib10","doi-asserted-by":"crossref","first-page":"437","DOI":"10.3389\/fphar.2018.00437","article-title":"Bushen Huoxue recipe alleviates implantation loss in mice by enhancing estrogen-progesterone signals and promoting decidual angiogenesis through FGF2 during early pregnancy","volume":"9","author":"Ding","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2021.113789_bib11","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1074\/mcp.RA119.001461","article-title":"High-throughput exploration of the network dependent on AKT1 in mouse ovarian granulosa cells","volume":"18","author":"Elzaiat","year":"2019","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.jep.2021.113789_bib12","first-page":"78","article-title":"Epigenetic aberration of FMR1 gene in infertile women with diminished ovarian reserve","volume":"20","author":"Eslami","year":"2018","journal-title":"Cell J. l"},{"key":"10.1016\/j.jep.2021.113789_bib13","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1007\/s10815-019-01446-5","article-title":"Apoptosis of mural granulosa cells is increased in women with diminished ovarian reserve","volume":"36","author":"Fan","year":"2019","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.jep.2021.113789_bib14","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1007\/s10815-014-0257-5","article-title":"Genetic associations with diminished ovarian reserve: a systematic review of the literature","volume":"31","author":"Greene","year":"2014","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.jep.2021.113789_bib15","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1093\/humrep\/dey250","article-title":"Dynamics of PI3K and Hippo signaling pathways during in vitro human follicle activation","volume":"33","author":"Grosbois","year":"2018","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jep.2021.113789_bib16","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1634\/theoncologist.2013-0145","article-title":"Prediction of postchemotherapy ovarian function using markers of ovarian reserve","volume":"19","author":"Henry","year":"2014","journal-title":"Oncol."},{"key":"10.1016\/j.jep.2021.113789_bib17","series-title":"Physiology. Ovulation. Treasure Island (FL)","author":"Holesh","year":"2020"},{"key":"10.1016\/j.jep.2021.113789_bib18","doi-asserted-by":"crossref","first-page":"277","DOI":"10.4149\/gpb_2019059","article-title":"Cryptotanshinone decreases granulosa cell apoptosis and restores ovarian function in mice with premature ovarian failure","volume":"39","author":"Huang","year":"2020","journal-title":"Gen. Physiol. Biophys."},{"key":"10.1016\/j.jep.2021.113789_bib19","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.maturitas.2019.10.011","article-title":"Analysis of NR5A1 in 142 patients with premature ovarian insufficiency, diminished ovarian reserve, or unexplained infertility","volume":"131","author":"Jaillard","year":"2020","journal-title":"Maturitas"},{"key":"10.1016\/j.jep.2021.113789_bib20","article-title":"Traditional Chinese herb for low endometrial receptivity and its effect on pregnancy: protocol for a systematic review and meta-analysis","volume":"98","author":"Jiang","year":"2019","journal-title":"Medicine (Baltim.)"},{"key":"10.1016\/j.jep.2021.113789_bib21","doi-asserted-by":"crossref","first-page":"546","DOI":"10.3389\/fphar.2020.00546","article-title":"Protective effects and possible mechanisms of actions of Bushen Cuyun recipe on diminished ovarian reserve induced by cyclophosphamide in rats","volume":"11","author":"Jiang","year":"2020","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2021.113789_bib22","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s10815-011-9684-8","article-title":"Impaired gremlin 1 (GREM1) expression in cumulus cells in young women with diminished ovarian reserve (DOR)","volume":"29","author":"Jindal","year":"2012","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.jep.2021.113789_bib23","first-page":"3971","article-title":"Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri","volume":"117","author":"Jurisicova","year":"2007","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jep.2021.113789_bib24","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3005402","article-title":"Cyclophosphamide triggers follicle activation and \u201cburnout\u201d; AS101 prevents follicle loss and preserves fertility","volume":"5","author":"Kalich-Philosoph","year":"2013","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.jep.2021.113789_bib25","doi-asserted-by":"crossref","first-page":"21925","DOI":"10.1038\/s41598-020-79013-7","article-title":"Samul-tang ameliorates oocyte damage due to cyclophosphamide-induced chronic ovarian dysfunction in mice","volume":"10","author":"Kim","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2021.113789_bib26","doi-asserted-by":"crossref","first-page":"109218","DOI":"10.1016\/j.biopha.2019.109218","article-title":"Icariin exerts a protective effect against d-galactose induced premature ovarian failure via promoting DNA damage repair","volume":"118","author":"Li","year":"2019","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2021.113789_bib27","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s13287-019-1508-2","article-title":"Small extracellular vesicles derived from embryonic stem cells restore ovarian function of premature ovarian failure through PI3K\/AKT signaling pathway","volume":"11","author":"Liu","year":"2020","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.jep.2021.113789_bib28","series-title":"The Effect of Bushen Tiaojing Recipe on the Expression of Ovarian Granular Apoptosis and Caspase-3 in ASR","first-page":"4","author":"Ma","year":"2008"},{"key":"10.1016\/j.jep.2021.113789_bib29","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s12522-014-0195-z","article-title":"Clomiphene citrate affects the receptivity of the uterine endometrium","volume":"14","author":"Nakagawa","year":"2015","journal-title":"Reprod. Med. Biol."},{"key":"10.1016\/j.jep.2021.113789_bib30","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.reprotox.2020.05.005","article-title":"The protective effects of pretreatment with resveratrol in cyclophosphamide-induced rat ovarian granulosa cell injury: in vitro study","volume":"95","author":"Nie","year":"2020","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.jep.2021.113789_bib31","first-page":"29","article-title":"Clinical observation of 30 cases with decreased ovarian reserve function treated with Zishen Yijing decoction and acupuncture","volume":"23","author":"Pan","year":"2014","journal-title":"Chin. J. Ethnomed. Ethnopharmacy"},{"key":"10.1016\/j.jep.2021.113789_bib32","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s10815-017-1058-4","article-title":"Reproductive ovarian testing and the alphabet soup of diagnoses: DOR, POI, POF, POR, and FOR","volume":"35","author":"Pastore","year":"2018","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.jep.2021.113789_bib33","doi-asserted-by":"crossref","first-page":"111855","DOI":"10.1016\/j.jep.2019.111855","article-title":"Zuogui Pills inhibit mitochondria-dependent apoptosis of follicles in a rat model of premature ovarian failure","volume":"238","author":"Peng","year":"2019","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2021.113789_bib34","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.mce.2017.11.002","article-title":"The effect of ovarian reserve and receptor signalling on granulosa cell apoptosis during human follicle development","volume":"470","author":"Regan","year":"2018","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.jep.2021.113789_bib35","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1023\/A:1009422323306","article-title":"Effects of aging on ovarian fecundity in terms of the incidence of apoptotic granulosa cells","volume":"17","author":"Sadraie","year":"2000","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.jep.2021.113789_bib36","doi-asserted-by":"crossref","first-page":"3441","DOI":"10.1210\/jcem.87.7.8676","article-title":"Stimulation of apoptosis in human granulosa cells from in vitro fertilization patients and its prevention by dexamethasone: involvement of cell contact and Bcl-2 expression","volume":"87","author":"Sasson","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jep.2021.113789_bib37","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1055\/s-0030-1255174","article-title":"Ethics and reproductive medicine. Preface","volume":"28","author":"Sauer","year":"2010","journal-title":"Semin. Reprod. Med."},{"key":"10.1016\/j.jep.2021.113789_bib38","doi-asserted-by":"crossref","first-page":"108687","DOI":"10.1016\/j.biopha.2019.108687","article-title":"Efficacy of electroacupuncture in regulating the imbalance of AMH and FSH to improve follicle development and hyperandrogenism in PCOS rats","volume":"113","author":"Shi","year":"2019","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2021.113789_bib39","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13063-020-04502-z","article-title":"Efficacy and safety of Dingkun pill for female infertility patients with low prognosis undergoing in vitro fertilization-embryo transfer: study protocol for a multicenter, double-blind, randomized, placebo-controlled trial","volume":"21","author":"Song","year":"2020","journal-title":"Trials"},{"key":"10.1016\/j.jep.2021.113789_bib40","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1093\/humupd\/dmz027","article-title":"Ovarian damage from chemotherapy and current approaches to its protection","volume":"25","author":"Spears","year":"2019","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jep.2021.113789_bib41","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1016\/j.fertnstert.2016.09.046","article-title":"Hormone replacement therapy in young women with primary ovarian insufficiency and early menopause","volume":"106","author":"Sullivan","year":"2016","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jep.2021.113789_bib42","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1093\/molehr\/gaaa043","article-title":"Unraveling the mechanisms of chemotherapy-induced damage to human primordial follicle reserve: road to developing therapeutics for fertility preservation and reversing ovarian aging","volume":"26","author":"Szymanska","year":"2020","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.jep.2021.113789_bib43","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ajog.2017.02.027","article-title":"Ovarian reserve testing: a user's guide","volume":"217","author":"Tal","year":"2017","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.jep.2021.113789_bib44","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0120048","article-title":"The TP73 gene polymorphism (rs4648551, A>G) is associated with diminished ovarian reserve","volume":"10","author":"Vagnini","year":"2015","journal-title":"PloS One"},{"key":"10.1016\/j.jep.2021.113789_bib45","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.theriogenology.2018.10.028","article-title":"Effects of icariin on ovarian function in d-galactose-induced aging mice","volume":"125","author":"Wang","year":"2019","journal-title":"Theriogenology"},{"key":"10.1016\/j.jep.2021.113789_bib46","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/s13048-019-0585-2","article-title":"Baicalin ameliorates polycystic ovary syndrome through AMP-activated protein kinase","volume":"12","author":"Wang","year":"2019","journal-title":"J. Ovarian Res."},{"key":"10.1016\/j.jep.2021.113789_bib47","doi-asserted-by":"crossref","first-page":"390","DOI":"10.3389\/fphar.2018.00390","article-title":"Identification of steroidogenic components derived from Gardenia jasminoides Ellis potentially useful for treating postmenopausal syndrome","volume":"9","author":"Wang","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2021.113789_bib48","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1016\/j.fertnstert.2020.06.035","article-title":"Low klothom level related to aging is associated with diminished ovarian reserve","volume":"114","author":"Xu","year":"2020","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jep.2021.113789_bib49","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.22591","article-title":"Protective roles and mechanisms of rosmarinic acid in cyclophosphamide-induced premature ovarian failure","author":"Yao","year":"2020","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.jep.2021.113789_bib50","doi-asserted-by":"crossref","first-page":"2987","DOI":"10.2147\/OTT.S242703","article-title":"The protective effect of testosterone on the ovarian reserve during cyclophosphamide treatment","volume":"13","author":"Yoo","year":"2020","journal-title":"OncoTargets Ther."},{"key":"10.1016\/j.jep.2021.113789_bib51","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.3892\/etm.2016.3025","article-title":"Advancement in the treatment of diminished ovarian reserve by traditional Chinese and Western medicine","volume":"11","author":"Zhang","year":"2016","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.jep.2021.113789_bib52","doi-asserted-by":"crossref","first-page":"111885","DOI":"10.1016\/j.jep.2019.111885","article-title":"Kuntai capsule attenuates premature ovarian failure through the PI3K\/AKT\/mTOR pathway","volume":"239","author":"Zhang","year":"2019","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2021.113789_bib53","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.mce.2011.05.027","article-title":"Functional roles of the phosphatidylinositol 3-kinases (PI3Ks) signaling in the mammalian ovary","volume":"356","author":"Zheng","year":"2012","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.jep.2021.113789_bib54","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s13048-017-0350-3","article-title":"Rapamycin prevents cyclophosphamide-induced over-activation of primordial follicle pool through PI3K\/Akt\/mTOR signaling pathway in vivo","volume":"10","author":"Zhou","year":"2017","journal-title":"J. Ovarian Res."},{"key":"10.1016\/j.jep.2021.113789_bib55","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0166751","article-title":"Chlorogenic acid prevents osteoporosis by Shp2\/PI3K\/Akt pathway in ovariectomized rats","volume":"11","author":"Zhou","year":"2016","journal-title":"PloS One"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874121000155?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874121000155?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:07:58Z","timestamp":1759943278000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874121000155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":55,"alternative-id":["S0378874121000155"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2021.113789","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Zihuai recipe alleviates cyclophosphamide-induced diminished ovarian reserve via suppressing PI3K\/AKT-mediated apoptosis","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2021.113789","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"113789"}}