{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:28:08Z","timestamp":1762432088447,"version":"build-2065373602"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100008402","name":"Chengdu University of Traditional Chinese Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008402","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.jep.2021.114551","type":"journal-article","created":{"date-parts":[[2021,8,21]],"date-time":"2021-08-21T10:41:11Z","timestamp":1629542471000},"page":"114551","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["The efficacy and safety of Xuefu Zhuyu Decoction combined with Mifepristone in the treatment of uterine leiomyoma: A systematic review and meta-analysis"],"prefix":"10.1016","volume":"281","author":[{"given":"Shasha","family":"Shi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiaobo","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenghao","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fu","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jep.2021.114551_bib1","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1067\/mob.2003.99","article-title":"High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence","volume":"188","author":"Baird","year":"2003","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"9","key":"10.1016\/j.jep.2021.114551_bib2","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1177\/1933719116678686","article-title":"Estrogen receptors and signaling in fibroids: role in pathobiology and therapeutic implications","volume":"24","author":"Borahay","year":"2017","journal-title":"Reprod. Sci."},{"issue":"38","key":"10.1016\/j.jep.2021.114551_bib3","article-title":"Observation on clinical efficacy of xuefu zhuyu decoction combined with mifepristone in treating uterine leiomyoma","author":"Chen","year":"2014","journal-title":"Scientific Consultation"},{"issue":"12","key":"10.1016\/j.jep.2021.114551_bib4","doi-asserted-by":"crossref","DOI":"10.3390\/ijms18122586","article-title":"Alternative oral agents in prophylaxis and therapy of uterine fibroids-an up-to-date review","volume":"18","author":"Ciebiera","year":"2017","journal-title":"Int. J. Mol. Sci."},{"issue":"9","key":"10.1016\/j.jep.2021.114551_bib5","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2016-015571","article-title":"Economic impact of ulipristal acetate on surgical procedures for uterine fibroids in France","volume":"7","author":"Fernandez","year":"2017","journal-title":"BMJ Open"},{"issue":"1-a Suppl. l","key":"10.1016\/j.jep.2021.114551_bib6","first-page":"S2","article-title":"Direct costs incurred among women undergoing surgical procedures to treat uterine fibroids","volume":"26","author":"Harrington","year":"2020","journal-title":"J Manag Care Spec Pharm"},{"key":"10.1016\/j.jep.2021.114551_bib10","series-title":"Treating 55 Cases of Uterine Leiomyoma with Modified Xuefu Zhuyu Decoction. Psychologists","first-page":"289","author":"He","year":"2012"},{"year":"2013","series-title":"Cochrane Reviewers' Handbook Version 5.2","author":"Higgins","key":"10.1016\/j.jep.2021.114551_bib7"},{"issue":"28","key":"10.1016\/j.jep.2021.114551_bib8","article-title":"To study the clinical efficacy of Xuefu Zhuyu Decoction combined with mifepristone in the treatment of uterine leiomyoma","volume":"11","author":"Hu","year":"2019","journal-title":"Clinical Research of Traditional Chinese Medicine"},{"issue":"2","key":"10.1016\/j.jep.2021.114551_bib9","first-page":"77","article-title":"Observation on efficacy and safety of modified xuefu zhuyu decoction in treating uterine leiomyoma patients","author":"Huang","year":"2018","journal-title":"Maternal and Infant World"},{"issue":"3","key":"10.1016\/j.jep.2021.114551_bib11","first-page":"421","article-title":"Therapeutic effect of xuefu decoction on chronic pelvic inflammatory disease and its mechanism","author":"Jin","year":"2015","journal-title":"World Chinese medicine"},{"issue":"5","key":"10.1016\/j.jep.2021.114551_bib12","first-page":"254","article-title":"Practice guideline of evidence-based medicine: preferred reporting items for systematic reviews and meta-analyses (the PRISMA statement)","volume":"54","author":"Kyoko","year":"2011","journal-title":"Journal of Information Processing & Management\/Joho Kanri"},{"issue":"8","key":"10.1016\/j.jep.2021.114551_bib13","first-page":"1155","article-title":"Clinical observation of cassia tuckaing pill hexuefu zhuyu decoction in the treatment of ovarian cyst","volume":"25","author":"Li","year":"2003","journal-title":"Chinese journal of basic medicine of traditional Chinese medicine"},{"key":"10.1016\/j.jep.2021.114551_bib14","series-title":"Chief Editor. Concise Dictionary of Traditional Chinese Medicine","volume":"vol. 3","author":"Li","year":"2001"},{"issue":"20","key":"10.1016\/j.jep.2021.114551_bib23","article-title":"Effect of xuefu zhuyu decoction on adjuvant treatment of uterine leiomyoma and its influence on LH, E2 and FSH levels of patients","volume":"32","author":"Li","year":"2017","journal-title":"China Maternal and Child Health Care"},{"key":"10.1016\/j.jep.2021.114551_bib15","doi-asserted-by":"crossref","first-page":"109624","DOI":"10.1016\/j.biopha.2019.109624","article-title":"Molecular targeted study in tumors: from western medicine to active ingredients of traditional Chinese medicine","volume":"121","author":"Li","year":"2020","journal-title":"Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie"},{"issue":"34","key":"10.1016\/j.jep.2021.114551_bib16","first-page":"86","article-title":"Application of xuefu zhuyu decoction in clinical treatment of uterine leiomyoma","volume":"27","author":"Liu","year":"2017","journal-title":"China Health Nutrition"},{"key":"10.1016\/j.jep.2021.114551_bib17","first-page":"1","article-title":"Minimally invasive myomectomy: an overview on the surgical approaches and a comparison with mini-laparotomy","author":"Mar\u00edn-Buck","year":"2019","journal-title":"J. Invest. Surg. : the official journal of the Academy of Surgical Research"},{"issue":"9","key":"10.1016\/j.jep.2021.114551_bib19","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1002\/pd.5505","article-title":"Fetal arthrogryposis multiplex congenita\/fetal akinesia deformation sequence (FADS)-Aetiology, diagnosis, and management","volume":"39","author":"Niles","year":"2019","journal-title":"Prenat. Diagn."},{"issue":"14","key":"10.1016\/j.jep.2021.114551_bib20","article-title":"Clinical observation of xuefu zhuyu decoction combined with mifepristone in treating uterine leiomyoma","volume":"23","author":"Peng","year":"2014","journal-title":"modern journal of integrated traditional chinese and western medicine"},{"issue":"7","key":"10.1016\/j.jep.2021.114551_bib21","article-title":"Xuefu zhuyu decoction combined with mifepristone in treating 30 cases of uterine leiomyoma","author":"Peng","year":"2017","journal-title":"Chinese Journal of Ethnic and Folk Medicine"},{"year":"2018","series-title":"Traditional Chinese Medicine Clinical Practical Classic Series Yilingaicuo Large Edition. Beijing","author":"Qing","key":"10.1016\/j.jep.2021.114551_bib22"},{"issue":"12","key":"10.1016\/j.jep.2021.114551_bib24","first-page":"716","article-title":"Relationship of uterine fibroids with lipid profile, anthropometric characteristics, subcutaneous and preperitoneal fat thickness","volume":"22","author":"Sharami","year":"2019","journal-title":"Arch. Iran. Med."},{"issue":"4","key":"10.1016\/j.jep.2021.114551_bib25","doi-asserted-by":"crossref","first-page":"289","DOI":"10.21010\/ajtcam.v14i4.32","article-title":"IN VIVO effect OF guiding-herb radix PLATYCODONIS and radix CYATHULAE ON paeoniflorin pharmacokinetics OF xuefu zhuyu tang IN rats","volume":"14","author":"Tang","year":"2017","journal-title":"Afr. J. Tradit., Complementary Altern. Med. : AJTCAM"},{"issue":"2","key":"10.1016\/j.jep.2021.114551_bib26","first-page":"115","article-title":"Clinical efficacy analysis of xuefu zhuyu decoction combined with mifepristone in treating uterine leiomyoma","author":"Tian","year":"2013","journal-title":"Oncology Pharmacy"},{"issue":"20","key":"10.1016\/j.jep.2021.114551_bib27","first-page":"113","article-title":"Effect of mifepristone combined with xuefuzhuyu decoction in the treatment of uterine fibroids","volume":"17","author":"Wang","year":"2002","journal-title":"J. Contemp. Med."},{"issue":"38","key":"10.1016\/j.jep.2021.114551_bib28","first-page":"214","article-title":"Efficacy and safety of xuefu zhuyu decoction combined with mifepristone in treatment of uterine leiomyoma","author":"Wang","year":"2019","journal-title":"Guidelines for Health Care"},{"issue":"3","key":"10.1016\/j.jep.2021.114551_bib29","article-title":"Xuefu zhuyu decoction combined with mifepristone for 100 cases of uterine leiomyoma","volume":"36","author":"Yang","year":"2016","journal-title":"Henan Traditional Chinese Medicine"},{"issue":"11","key":"10.1016\/j.jep.2021.114551_bib30","article-title":"Observation on the efficacy of xuefu zhuyu decoction in adjuvant treatment of uterine leiomyoma","volume":"18","author":"Yang","year":"2018","journal-title":"Clinical Application of Integrated Traditional Chinese and Western Medicine"},{"issue":"12","key":"10.1016\/j.jep.2021.114551_bib31","first-page":"1517","article-title":"Clinical observation on the treatment of xuefu zhuyu decoction","volume":"35","author":"Zhang","year":"2009","journal-title":"Journal of practical Chinese medicine"},{"issue":"6","key":"10.1016\/j.jep.2021.114551_bib33","first-page":"1408","article-title":"Effects of Xuefu Zhuyu Decoction on NOS, TNF-a, IL-2 levels and uterine smooth muscle thickness in uterine leiomyoma model rats","volume":"14","author":"Zhou","year":"2019","journal-title":"World Traditional Chinese Medicine"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874121007807?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874121007807?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T01:51:19Z","timestamp":1762307479000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874121007807"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":31,"alternative-id":["S0378874121007807"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2021.114551","relation":{},"ISSN":["0378-8741"],"issn-type":[{"type":"print","value":"0378-8741"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The efficacy and safety of Xuefu Zhuyu Decoction combined with Mifepristone in the treatment of uterine leiomyoma: A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2021.114551","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"114551"}}