{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T23:17:41Z","timestamp":1784675861497,"version":"3.55.0"},"reference-count":128,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100009009","name":"Heilongjiang University of Chinese Medicine","doi-asserted-by":"publisher","award":["LH2019H102"],"award-info":[{"award-number":["LH2019H102"]}],"id":[{"id":"10.13039\/501100009009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010009","name":"Heilongjiang Provincial Postdoctoral Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81703719"],"award-info":[{"award-number":["81703719"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["LBH-TZ1620"],"award-info":[{"award-number":["LBH-TZ1620"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005046","name":"Natural Science Foundation of Heilongjiang Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005046","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.jep.2022.115320","type":"journal-article","created":{"date-parts":[[2022,4,25]],"date-time":"2022-04-25T23:25:05Z","timestamp":1650929105000},"page":"115320","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"special_numbering":"C","title":["Exploring the effects of Chinese herbal ingredients on the signaling pathway of alopecia and the screening of effective Chinese herbal compounds"],"prefix":"10.1016","volume":"294","author":[{"given":"jinjin","family":"Dou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianrong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiwu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2022.115320_bib2","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s00441-015-2300-y","article-title":"Wnt\/\u03b2-catenin signaling in bone marrow niche","volume":"363","author":"Ahmadzadeh","year":"2016","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.jep.2022.115320_bib3","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1046\/j.1365-2133.1999.03042.x","article-title":"Immunohistochemical localization of types 1 and 2 5alpha-reductase in human scalp","volume":"141","author":"Bayne","year":"1999","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib4","doi-asserted-by":"crossref","first-page":"496","DOI":"10.3892\/ijmm.2014.2022","article-title":"Exogenous stimulation with Eclipta alba promotes hair matrix keratinocyte proliferation and downregulates TGF-\u03b21 expression in nude mice","volume":"35","author":"Begum","year":"2015","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.jep.2022.115320_bib5","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.biocel.2004.10.013","article-title":"The signals and pathways activate cellular senescence","volume":"37","author":"Ben-Porath","year":"2005","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.jep.2022.115320_bib6","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1126\/science.282.5387.290","article-title":"Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis","volume":"282","author":"Bennett","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.jep.2022.115320_bib7","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/sj.jid.5700007","article-title":"Apoptosis in the hair follicle","volume":"126","author":"Botchkareva","year":"2006","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib8","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1038\/sj.leu.2402824","article-title":"Involvement of PI3K\/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy","volume":"17","author":"Chang","year":"2003","journal-title":"Leukemia"},{"issue":"12","key":"10.1016\/j.jep.2022.115320_bib9","first-page":"47","article-title":"Syndrome differentiation and treatment of androgenic alopecia","volume":"42","author":"Chen","year":"2008","journal-title":"Shanghai J. Tradit. Chin. Med. 2008"},{"key":"10.1016\/j.jep.2022.115320_bib10","first-page":"1380146","article-title":"Tetrahydroxystilbene glucoside effectively prevents apoptosis induced hair loss","volume":"2018","author":"Chen","year":"2018","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.jep.2022.115320_bib11","series-title":"The Correlation between IGF-1, FGF7 and Biological Characteristics of Dermal Papilla Cells and the Effects of SNMC and Dexameth on the Activity of Dermal Papilla Cells","author":"Cheng","year":"2010"},{"key":"10.1016\/j.jep.2022.115320_bib12","doi-asserted-by":"crossref","first-page":"112907","DOI":"10.1016\/j.jep.2020.112907","article-title":"A comprehensive review of biochemical factors in herbs and their constituent compounds in experimental studies on alopecia","volume":"258","author":"Cho","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2022.115320_bib13","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.bbamcr.2007.11.017","article-title":"HIF-1alpha controls keratinocyte proliferation by up-regulating p21(WAF1\/Cip1)","volume":"1783","author":"Cho","year":"2008","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jep.2022.115320_bib14","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1080\/09168451.2017.1385383","article-title":"Titrated extract of Centella asiatica increases hair inductive property through inhibition of STAT signaling pathway in three-dimensional spheroid cultured human dermal papilla cells","volume":"81","author":"Choi","year":"2017","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1016\/j.jep.2022.115320_bib15","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1038\/jid.2011.137","article-title":"Impaired keratinocyte proliferative and clonogenic potential in transgenic mice overexpressing 14-3-3\u03c3 in the epidermis","volume":"131","author":"Cianfarani","year":"2011","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib16","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/j.cell.2012.05.012","article-title":"Wnt\/\u03b2-catenin signaling and disease","volume":"149","author":"Clevers","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.jep.2022.115320_bib17","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.gde.2004.07.002","article-title":"Transcriptional control of epidermal specification and differentiation","volume":"14","author":"Dai","year":"2004","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.jep.2022.115320_bib18","first-page":"185","article-title":"Improved wool production in transgenic sheep expressing insulin-like growth factor 1","volume":"14","author":"Damak","year":"1996","journal-title":"Biotechnology"},{"key":"10.1016\/j.jep.2022.115320_bib19","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0303-7207(92)90004-P","article-title":"Testosterone and 5\u03b1-dihydrotestosterone interact differently with the androgen receptor to enhance transcription of the MMTV-CAT reporter gene","volume":"88","author":"Deslypere","year":"1992","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.jep.2022.115320_bib20","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1111\/jocd.12930","article-title":"An overview of herbal alternatives in androgenetic alopecia","volume":"18","author":"Dhariwala","year":"2019","journal-title":"J. Cosmet. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib21","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1046\/j.1523-1747.1998.00224.x","article-title":"Genetic analysis of male pattern baldness and the 5alpha-reductase genes","volume":"110","author":"Ellis","year":"1998","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib23","series-title":"Zhong Guo Pi Fu Bing Xing Bing Xue[Chinese Dermatology & Venereology]","author":"Fan","year":"2010"},{"key":"10.1016\/j.jep.2022.115320_bib24","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/jocd.12171","article-title":"Assessment of tissue levels of dickkopf-1 in androgenetic alopecia and alopecia","volume":"15","author":"Fawzi","year":"2016","journal-title":"J. Cosmet. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib25","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1096\/fasebj.14.5.752","article-title":"Control of murine hair follicle regression (catagen) by TGF-beta1 in vivo","volume":"14","author":"Foitzik","year":"2000","journal-title":"Faseb. J."},{"key":"10.1016\/j.jep.2022.115320_bib26","doi-asserted-by":"crossref","first-page":"C1593","DOI":"10.1152\/ajpcell.00537.2002","article-title":"Cyclosporin A-induced hair growth in mice is associated with inhibition of calcineurin-dependent activation of NFAT in follicular keratinocytes","volume":"284","author":"Gafter-Gvili","year":"2003","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.jep.2022.115320_bib27","doi-asserted-by":"crossref","first-page":"126ra34","DOI":"10.1126\/scitranslmed.3003122","article-title":"Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia","volume":"4","author":"Garza","year":"2012","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.jep.2022.115320_bib28","first-page":"258","article-title":"Identification and treatment of 290 cases of seborrheic alopecia","volume":"6","author":"Han","year":"1996","journal-title":"Zhejiang J. Tradit. Chin. Med. 1996"},{"key":"10.1016\/j.jep.2022.115320_bib29","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1210\/er.2007-0019","article-title":"Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex","volume":"28","author":"Heemers","year":"2007","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.jep.2022.115320_bib30","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1126\/science.8091232","article-title":"Mediation of c-Myc-induced apoptosis by p53","volume":"265","author":"Hermeking","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.jep.2022.115320_bib31","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jdermsci.2003.12.003","article-title":"Role of TGF-beta2 in the human hair cycle","volume":"35","author":"Hibino","year":"2004","journal-title":"J. Dermatol. Sci."},{"issue":"5","key":"10.1016\/j.jep.2022.115320_bib32","first-page":"620","article-title":"Clinical study on the analysis of male pattern baldness scale and finasteride treatment in 320 cases","volume":"30","author":"Hu","year":"2009","journal-title":"J. Xi'an Jiaotong Univ., Med. Sci."},{"key":"10.1016\/j.jep.2022.115320_bib130","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.cell.2010.11.049","article-title":"Dynamics between stem cells, niche, and progeny in the hair follicle","volume":"144","author":"Hsu","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.jep.2022.115320_bib33","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aba1685","article-title":"Dermal exosomes containing miR-218-5p promote hair regeneration by regulating \u03b2-catenin signaling","volume":"6","author":"Hu","year":"2020","journal-title":"Sci. Adv."},{"key":"10.1016\/j.jep.2022.115320_bib34","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.pharmthera.2018.11.008","article-title":"Activating Wnt\/\u03b2-catenin signaling pathway for disease therapy: challenges and opportunities","volume":"196","author":"Huang","year":"2019","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.jep.2022.115320_bib35","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1007\/s00403-009-0931-0","article-title":"A cell-based system for screening hair growth-promoting agents","volume":"301","author":"Huh","year":"2009","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.jep.2022.115320_bib36","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1161\/01.RES.0000185823.73556.06","article-title":"Adenosine monophosphate-activated protein kinase suppresses vascular smooth muscle cell proliferation through the inhibition of cell cycle progression","volume":"97","author":"Igata","year":"2005","journal-title":"Circ. Res."},{"key":"10.1016\/j.jep.2022.115320_bib37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jdermsci.2010.10.015","article-title":"Molecular basis of androgenetic alopecia: from androgen to paracrine mediators through dermal papilla","volume":"61","author":"Inui","year":"2011","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.jep.2022.115320_bib38","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1096\/fj.02-0043fje","article-title":"Androgen-inducible TGF-beta1 from balding dermal papilla cells inhibits epithelial cell growth: a clue to understand paradoxical effects of androgen on human hair growth","volume":"16","author":"Inui","year":"2002","journal-title":"Faseb. J."},{"key":"10.1016\/j.jep.2022.115320_bib39","first-page":"599","article-title":"An approach to patients with alopecia","volume":"105","author":"Jamerson","year":"2021","journal-title":"Med. Clin."},{"key":"10.1016\/j.jep.2022.115320_bib40","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1046\/j.1523-1747.1998.00144.x","article-title":"Local injection of hepatocyte growth factor\/scatter factor (HGF\/SF) alters cyclic growth of murine hair follicles","volume":"110","author":"Jindo","year":"1998","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib41","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1600-0560.2006.00585.x","article-title":"P63 expression pattern during rat epidermis morphogenesis and the role of p63 as a marker for epidermal stem cells","volume":"34","author":"Kai-Hong","year":"2007","journal-title":"J. Cutan. Pathol."},{"key":"10.1016\/j.jep.2022.115320_bib42","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.3390\/md11061783","article-title":"The promoting effect of Ishige sinicola on hair growth","volume":"11","author":"Kang","year":"2013","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.jep.2022.115320_bib43","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.jaad.2011.08.019","article-title":"Clinical evaluation of alopecias using a handheld dermatoscope","volume":"67","author":"Karada\u011f K\u00f6se","year":"2012","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib44","first-page":"396","article-title":"Pathological roles of MAPK signaling pathways in human diseases","author":"Kim","year":"2010","journal-title":"Biochim Biophys Acta 1802"},{"key":"10.1016\/j.jep.2022.115320_bib45","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/j.tiv.2009.07.036","article-title":"Anti-inflammatory effect of leaves of Eriobotrya japonica correlating with attenuation of p38 MAPK, ERK, and NF-kappaB activation in mast cells","volume":"23","author":"Kim","year":"2009","journal-title":"Toxicol. Vitro"},{"key":"10.1016\/j.jep.2022.115320_bib46","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1007\/s12272-012-0820-5","article-title":"Promotion effect of acankoreoside J, a lupane-triterpene in Acanthopanax koreanum, on hair growth","volume":"35","author":"Kim","year":"2012","journal-title":"Arch Pharm. Res. (Seoul)"},{"key":"10.1016\/j.jep.2022.115320_bib47","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1055\/s-0033-1360300","article-title":"The inhibitory effect of Scutellaria baicalensis extract and its active compound, baicalin, on the translocation of the androgen receptor with implications for preventing androgenetic alopecia","volume":"80","author":"Kim","year":"2014","journal-title":"Planta Med."},{"key":"10.1016\/j.jep.2022.115320_bib48","article-title":"Beneficial effects of Astragaloside IV for hair loss via inhibition of Fas\/Fas L-mediated apoptotic signaling","volume":"9","author":"Kim","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2022.115320_bib49","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1248\/bpb.b19-00254","article-title":"Hair growth promoting effect of hottuynia cordata extract in cultured human hair follicle dermal papilla cells","volume":"42","author":"Kim","year":"2019","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.jep.2022.115320_bib50","article-title":"Quercitrin stimulates hair growth with enhanced expression of growth factors via activation of MAPK\/CREB signaling pathway","volume":"25","author":"Kim","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2022.115320_bib51","doi-asserted-by":"crossref","first-page":"5579","DOI":"10.1002\/j.1460-2075.1995.tb00245.x","article-title":"Cytotoxicity-dependent APO-1 (Fas\/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor","volume":"14","author":"Kischkel","year":"1995","journal-title":"EMBO J."},{"key":"10.1016\/j.jep.2022.115320_bib52","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1101\/gad.14.10.1181","article-title":"Wnt signaling maintains the hair-inducing activity of the dermal papilla","volume":"14","author":"Kishimoto","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.jep.2022.115320_bib53","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.fsc.2020.01.001","article-title":"Hair transplantation for scarring alopecia","volume":"28","author":"Kumar","year":"2020","journal-title":"Facial Plast Surg Clin North Am"},{"key":"10.1016\/j.jep.2022.115320_bib54","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/sj.jid.5700999","article-title":"Dihydrotestosterone-inducible dickkopf 1 from balding dermal papilla cells causes apoptosis in follicular keratinocytes","volume":"128","author":"Kwack","year":"2008","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib55","doi-asserted-by":"crossref","first-page":"688","DOI":"10.5483\/BMBRep.2010.43.10.688","article-title":"Preventable effect of L-threonate, an ascorbate metabolite, on androgen-driven balding via repression of dihydrotestosterone-induced dickkopf-1 expression in human hair dermal papilla cells","volume":"43","author":"Kwack","year":"2010","journal-title":"BMB Rep"},{"key":"10.1016\/j.jep.2022.115320_bib56","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/1523-1747.ep12326964","article-title":"Vascular endothelial growth factor is an autocrine growth factor for hair dermal papilla cells","volume":"106","author":"Lachgar","year":"1996","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib57","article-title":"Physcion, a novel inhibitor of 5\u03b1-reductase that promotes hair growth in vitro and in vivo","author":"Lao","year":"2021","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.jep.2022.115320_bib58","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.3892\/ijmm.2017.3107","article-title":"Panax ginseng extract antagonizes the effect of DKK1-induced catagen-like changes of hair follicles","volume":"40","author":"Lee","year":"2017","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.jep.2022.115320_bib59","series-title":"The Regulation of Loureirin A to Promote Proliferation and Differentiation of Follicle Stem Cells and Loureirin A Repair Vibrissa Skin Wound of Rats","author":"Li","year":"2016"},{"key":"10.1016\/j.jep.2022.115320_bib60","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1111\/j.1365-2230.2011.04019.x","article-title":"Wnt10b promotes growth of hair follicles via a canonical Wnt signaling pathway","volume":"36","author":"Li","year":"2011","journal-title":"Clin. Exp. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib61","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1002\/ptr.4828","article-title":"Ginsenosides Rb\u2081 and Rd regulate proliferation of mature keratinocytes through induction of p63 expression in hair follicles","volume":"27","author":"Li","year":"2013","journal-title":"Phytother Res."},{"key":"10.1016\/j.jep.2022.115320_bib62","first-page":"517901","article-title":"Hair growth promotion activity and its mechanism of Polygonum multiflorum","author":"Li","year":"2015","journal-title":"Evid Based Complement Alternat Med 2015"},{"key":"10.1016\/j.jep.2022.115320_bib63","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1126\/science.1239730","article-title":"Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling","volume":"342","author":"Lim","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.jep.2022.115320_bib64","first-page":"24","article-title":"Advances in Chinese and Western medicine research on seborrheic alopecia","volume":"6","author":"Liu","year":"2003","journal-title":"Inf. Tradit. Chin. Med. 2003"},{"key":"10.1016\/j.jep.2022.115320_bib65","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.fitote.2017.07.007","article-title":"\u03b2-Catenin is involved in oleanolic acid-dependent promotion of proliferation in human hair matrix cells in an in vitro organ culture model","volume":"121","author":"Liu","year":"2017","journal-title":"Fitoterapia"},{"key":"10.1016\/j.jep.2022.115320_bib66","first-page":"18","article-title":"Professor Liu Yanchi's experience in treating seborrheic alopecia","volume":"6","author":"Ma","year":"2006","journal-title":"J. Anhui Univ. Chin. Med. 2006"},{"key":"10.1016\/j.jep.2022.115320_bib67","first-page":"WC01","article-title":"A hospital-based study to determine causes of diffuse hair loss in women","volume":"9","author":"Malkud","year":"2015","journal-title":"J. Clin. Diagn. Res."},{"key":"10.1016\/j.jep.2022.115320_bib68","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.bbamcr.2004.02.008","article-title":"Regulation of Bcl-2 proteins during anoikis and amorphosis","volume":"1692","author":"Martin","year":"2004","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jep.2022.115320_bib69","doi-asserted-by":"crossref","first-page":"4345","DOI":"10.1074\/jbc.273.8.4345","article-title":"Membrane oligomerization and cleavage activates the caspase-8 (FLICE\/MACHalpha1) death signal","volume":"273","author":"Martin","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jep.2022.115320_bib70","doi-asserted-by":"crossref","DOI":"10.1126\/science.aba2374","article-title":"Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring","volume":"372","author":"Mascharak","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.jep.2022.115320_bib71","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0065-2571(00)00021-2","article-title":"Synergistic effects of pi3k\/akt on abrogation of cytokine-dependency induced by oncogenic raf","volume":"41","author":"McCubrey","year":"2001","journal-title":"Adv. Enzym. Regul."},{"key":"10.1016\/j.jep.2022.115320_bib72","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2165\/00003495-200161010-00006","article-title":"Treatments for androgenetic alopecia and alopecia areata: current options and future prospects","volume":"61","author":"Meidan","year":"2001","journal-title":"Drugs"},{"key":"10.1016\/j.jep.2022.115320_bib73","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1172\/JCI119174","article-title":"Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1\/Fas) receptor\/ligand system and involves activation of wild-type p53","volume":"99","author":"M\u00fcller","year":"1997","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jep.2022.115320_bib74","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1084\/jem.188.11.2033","article-title":"p53 activates the CD95 (APO-1\/Fas) gene in response to DNA damage by anticancer drugs","volume":"188","author":"M\u00fcller","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jep.2022.115320_bib75","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1002\/ptr.4712","article-title":"Promotion of hair growth by Rosmarinus officinalis leaf extract","volume":"27","author":"Murata","year":"2013","journal-title":"Phytother Res."},{"key":"10.1016\/j.jep.2022.115320_bib76","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.bbrc.2007.05.135","article-title":"Effects of Wnt-10b on hair shaft growth in hair follicle cultures","volume":"359","author":"Ouji","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jep.2022.115320_bib77","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.bbrc.2007.12.091","article-title":"Wnt-10b, uniquely among Wnts, promotes epithelial differentiation and shaft growth","volume":"367","author":"Ouji","year":"2008","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jep.2022.115320_bib78","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1016\/S0142-9612(03)00045-0","article-title":"In vivo promoted growth of mice hair follicles by the controlled release of growth factors","volume":"24","author":"Ozeki","year":"2003","journal-title":"Biomaterials"},{"key":"10.1016\/j.jep.2022.115320_bib79","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.jep.2011.03.028","article-title":"Topical application of Polygonum multiflorum extract induces hair growth of resting hair follicles through upregulating Shh and \u03b2-catenin expression in C57BL\/6 mice","volume":"135","author":"Park","year":"2011","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2022.115320_bib80","doi-asserted-by":"crossref","first-page":"3156","DOI":"10.1073\/pnas.061032098","article-title":"p63 identifies keratinocyte stem cells","volume":"98","author":"Pellegrini","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jep.2022.115320_bib81","doi-asserted-by":"crossref","first-page":"10882","DOI":"10.1074\/jbc.272.16.10882","article-title":"Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2","volume":"272","author":"Prall","year":"1997","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.jep.2022.115320_bib82","article-title":"Professor Wei yuegang's clinical experience of syndrome differentiation in treating androgenetic alopecia","volume":"9","author":"Qin","year":"2014","journal-title":"World Chin. Med. 2014"},{"key":"10.1016\/j.jep.2022.115320_bib83","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/S0950-351X(05)80259-9","article-title":"9 Role of 5\u03b1-reductase in health and disease","volume":"8","author":"Randall","year":"1994","journal-title":"Bailliere. Clin. Endocrinol. Metabol."},{"key":"10.1016\/j.jep.2022.115320_bib84","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.phrs.2015.01.003","article-title":"Src protein-tyrosine kinase structure, mechanism, and small molecule inhibitors","volume":"94","author":"Roskoski","year":"2015","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.jep.2022.115320_bib85","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/j.0906-6705.2004.00203.x","article-title":"The water-soluble extract of Illicium anisatum stimulates mouse vibrissae follicles in organ culture","volume":"13","author":"Sakaguchi","year":"2004","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib86","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1346-8138.2011.01378.x","article-title":"Evaluation of efficacy and safety of finasteride 1 mg in 3177 Japanese men with androgenetic alopecia","volume":"39","author":"Sato","year":"2012","journal-title":"J. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib87","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1093\/jnci\/93.24.1858","article-title":"Effect of adenovirus-mediated expression of Sonic hedgehog gene on hair regrowth in mice with chemotherapy-induced alopecia","volume":"93","author":"Sato","year":"2001","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.jep.2022.115320_bib88","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1111\/1523-1747.ep12335779","article-title":"Different levels of 5alpha-reductase type I and II, aromatase, and androgen receptor in hair follicles of women and men with androgenetic alopecia","volume":"109","author":"Sawaya","year":"1997","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib89","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1093\/toxsci\/kft139","article-title":"The Fas\/Fas ligand apoptotic pathway is involved in abrin-induced apoptosis","volume":"135","author":"Saxena","year":"2013","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.jep.2022.115320_bib90","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1053\/sarh.2003.50005","article-title":"Apoptosis: programmed cell death at a molecular level","volume":"32","author":"Schultz","year":"2003","journal-title":"Semin. Arthritis Rheum."},{"key":"10.1016\/j.jep.2022.115320_bib91","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1073\/pnas.95.5.2307","article-title":"Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB","volume":"95","author":"Seitz","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jep.2022.115320_bib92","doi-asserted-by":"crossref","first-page":"5237","DOI":"10.1073\/pnas.90.11.5237","article-title":"Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice","volume":"90","author":"Sellheyer","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jep.2022.115320_bib93","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0092-8674(00)81902-9","article-title":"Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a","volume":"88","author":"Serrano","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.jep.2022.115320_bib94","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1002\/ptr.4870","article-title":"Hair growth activity of Crataegus pinnatifida on C57BL\/6 mouse model","volume":"27","author":"Shin","year":"2013","journal-title":"Phytother Res."},{"key":"10.1016\/j.jep.2022.115320_bib95","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1248\/bpb.b13-00771","article-title":"Ginsenoside F2 reduces hair loss by controlling apoptosis through the sterol regulatory element-binding protein cleavage activating protein and transforming growth factor-\u03b2 pathways in a dihydrotestosterone-induced mouse model","volume":"37","author":"Shin","year":"2014","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.jep.2022.115320_bib96","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.ejphar.2014.02.024","article-title":"The inductive effect of ginsenoside F2 on hair growth by altering the WNT signal pathway in telogen mouse skin","volume":"730","author":"Shin","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jep.2022.115320_bib97","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1002\/ptr.5324","article-title":"The androgenic alopecia protective effects of forsythiaside-A and the molecular regulation in a mouse model","volume":"29","author":"Shin","year":"2015","journal-title":"Phytother Res."},{"key":"10.1016\/j.jep.2022.115320_bib98","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1016\/S0960-9822(98)70443-9","article-title":"Sonic hedgehog signaling is essential for hair development","volume":"8","author":"St-Jacques","year":"1998","journal-title":"Curr. Biol."},{"key":"10.1016\/j.jep.2022.115320_bib99","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaad.2017.04.1141","article-title":"Alopecia areata: disease characteristics, clinical evaluation, and new perspectives on pathogenesis","volume":"78","author":"Strazzulla","year":"2018","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib100","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/ced.13043","article-title":"Icariin promotes mouse hair follicle growth by increasing insulin-like growth factor 1 expression in dermal papillary cells","volume":"42","author":"Su","year":"2017","journal-title":"Clin. Exp. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib101","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s40257-013-0010-3","article-title":"Health status, coping strategies, and alexithymia in subjects with androgenetic alopecia: a questionnaire study","volume":"14","author":"Tabolli","year":"2013","journal-title":"Am. J. Clin. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib102","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1056\/NEJMicm1801633","article-title":"Brittle nails and hair loss in hypothyroidism","volume":"379","author":"Taguchi","year":"2018","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jep.2022.115320_bib103","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/ced.12753","article-title":"Improvement of androgenetic alopecia with topical Sophora flavescens Aiton extract, and identification of the two active compounds in the extract that stimulate proliferation of human hair keratinocytes","volume":"41","author":"Takahashi","year":"2016","journal-title":"Clin. Exp. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib104","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1210\/jcem-34-6-1098","article-title":"The conversion of testosterone to 17 -hydroxy-5 -androstan-3-one (dihydrotestosterone) by human hair follicles","volume":"34","author":"Takayasu","year":"1972","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jep.2022.115320_bib105","series-title":"Plastrum Testudinis Extracts Promote Hair Follicle Stem Cell Proliferation and Wound Healing of SD Rat by Activating","author":"Tang","year":"2017"},{"key":"10.1016\/j.jep.2022.115320_bib106","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s12016-017-8620-9","article-title":"Alopecia areata: a comprehensive review of pathogenesis and management","volume":"54","author":"Tr\u00fceb","year":"2018","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"10.1016\/j.jep.2022.115320_bib107","doi-asserted-by":"crossref","first-page":"3185","DOI":"10.1101\/gad.1463206","article-title":"p63 regulates proliferation and differentiation of developmentally mature keratinocytes","volume":"20","author":"Truong","year":"2006","journal-title":"Genes Dev."},{"key":"10.1016\/j.jep.2022.115320_bib108","doi-asserted-by":"crossref","DOI":"10.3390\/molecules22091505","article-title":"Hair regenerative mechanisms of red ginseng oil and its major components in the testosterone-induced delay of anagen entry in C57BL\/6 mice","volume":"22","author":"Truong","year":"2017","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2022.115320_bib109","doi-asserted-by":"crossref","first-page":"207","DOI":"10.5114\/pdia.2014.40925","article-title":"Assessment of the usefulness of dihydrotestosterone in the diagnostics of patients with androgenetic alopecia","volume":"31","author":"Urysiak-Czubatka","year":"2014","journal-title":"Postepy Dermatol. Alergol."},{"key":"10.1016\/j.jep.2022.115320_bib110","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1080\/14728222.2019.1659779","article-title":"Androgenetic alopecia: combing the hair follicle signaling pathways for new therapeutic targets and more effective treatment options","volume":"23","author":"Vasserot","year":"2019","journal-title":"Expert Opin. Ther. Targets"},{"key":"10.1016\/j.jep.2022.115320_bib111","doi-asserted-by":"crossref","first-page":"57","DOI":"10.4103\/0974-7753.114701","article-title":"A descriptive study of alopecia patterns and their relation to thyroid dysfunction","volume":"5","author":"Vincent","year":"2013","journal-title":"Int. J. Trichol."},{"key":"10.1016\/j.jep.2022.115320_bib112","series-title":"A Study on the Correlation between the Pathogenesis of 214 Patients with Seborrheic Alopecia and the Identification of Chinese Medicine","author":"Wang","year":"2016"},{"key":"10.1016\/j.jep.2022.115320_bib113","series-title":"Hair Growth Promoting Effect of White Wax and Policosanol on the Mouse Model of Testosterone Induced Hair Loss","author":"Wang","year":"2017"},{"key":"10.1016\/j.jep.2022.115320_bib114","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1046\/j.1523-1747.2000.00951.x","article-title":"Regular articles: conditional disruption of hedgehog signaling pathway defines its critical role in hair development and regeneration","volume":"114","author":"Wang","year":"2000","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib115","first-page":"668","article-title":"A survey on the prevalence of baldness in six Chinese cities","volume":"10","author":"Wang","year":"2009","journal-title":"Chin. J. Dermatol. 2009"},{"key":"10.1016\/j.jep.2022.115320_bib116","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1111\/j.1365-2133.2010.09640.x","article-title":"Prevalence of androgenetic alopecia in China: a community-based study in six cities","volume":"162","author":"Wang","year":"2010","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.jep.2022.115320_bib117","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1126\/science.7973639","article-title":"The function of KGF in morphogenesis of epithelium and reepithelialization of wounds","volume":"266","author":"Werner","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.jep.2022.115320_bib118","first-page":"106","article-title":"Effects of ginsenoside Rb1 on TGF-beta1 induced p47phox expression and extracellular matrix accumulation in rat renal tubular epethelial cells","volume":"40","author":"Xie","year":"2009","journal-title":"Sichuan Da Xue Xue Bao Yi Xue Ban"},{"key":"10.1016\/j.jep.2022.115320_bib119","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s11655-009-0133-9","article-title":"Ginsenoside Rb1, a panoxadiol saponin against oxidative damage and renal interstitial fibrosis in rats with unilateral ureteral obstruction","volume":"15","author":"Xie","year":"2009","journal-title":"Chin. J. Integr. Med."},{"key":"10.1016\/j.jep.2022.115320_bib120","series-title":"The Mechanism of Active Ingredient Baicalin Facilitating Hair Growth","author":"Xing","year":"2018"},{"key":"10.1016\/j.jep.2022.115320_bib121","series-title":"Zhong Yi Pi Fu Xing Bing Xue[Chinese Medicine Dermatology]","author":"Yang","year":"2020"},{"issue":"9","key":"10.1016\/j.jep.2022.115320_bib122","first-page":"11","article-title":"Professor Cheng Yichun's experience in treating seborrheic alopecia by treating blood and dispelling wind","volume":"35","author":"Yang","year":"2014","journal-title":"Yunnan J. Tradit. Chin. Med. Mater. Med. 2014"},{"key":"10.1016\/j.jep.2022.115320_bib123","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1172\/JCI11317","article-title":"Control of hair growth and follicle size by VEGF-mediated angiogenesis","volume":"107","author":"Yano","year":"2001","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jep.2022.115320_bib131","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1248\/bpb.b18-00226","article-title":"Norgalanthamine Stimulates Proliferation of Dermal Papilla Cells via Anagen-Activating Signaling Pathways","volume":"42","author":"Yoon","year":"2019","journal-title":"Biol Pharm Bull"},{"key":"10.1016\/j.jep.2022.115320_bib124","doi-asserted-by":"crossref","first-page":"5733","DOI":"10.1242\/jcs.108969","article-title":"Ctip2 is a dynamic regulator of epidermal proliferation and differentiation by integrating EGFR and Notch signaling","volume":"125","author":"Zhang","year":"2012","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.jep.2022.115320_bib126","first-page":"440","article-title":"The pathogenesis and progress of drug therapy on seborrheic","volume":"4","author":"Zhao","year":"2016","journal-title":"Northwest Pharm. J."},{"key":"10.1016\/j.jep.2022.115320_bib127","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s00403-008-0907-5","article-title":"Angiogenin is expressed in human dermal papilla cells and stimulates hair growth","volume":"301","author":"Zhou","year":"2009","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.jep.2022.115320_bib128","doi-asserted-by":"crossref","first-page":"13785","DOI":"10.1038\/s41598-018-32138-2","article-title":"Morroniside regulates hair growth and cycle transition via activation of the Wnt\/\u03b2-catenin signaling pathway","volume":"8","author":"Zhou","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2022.115320_bib129","series-title":"Pi Fu Xing Bing xue[Dermatological Venereology]","author":"Zhu","year":"2002"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874122003592?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874122003592?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:21:27Z","timestamp":1759944087000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874122003592"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":128,"alternative-id":["S0378874122003592"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2022.115320","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exploring the effects of Chinese herbal ingredients on the signaling pathway of alopecia and the screening of effective Chinese herbal compounds","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2022.115320","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115320"}}