{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T22:58:21Z","timestamp":1772319501811,"version":"3.50.1"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.jep.2022.115330","type":"journal-article","created":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T02:02:31Z","timestamp":1651197751000},"page":"115330","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["An effective method for preventing cholestatic liver injury of Aucklandiae Radix and Vladimiriae Radix: Inflammation suppression and regulate the expression of bile acid receptors"],"prefix":"10.1016","volume":"294","author":[{"given":"Ziqiang","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunlei","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziwei","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ke","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zecheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6984-9377","authenticated-orcid":false,"given":"Huiling","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhan-guo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2022.115330_bib1","doi-asserted-by":"crossref","first-page":"s53","DOI":"10.5604\/01.3001.0010.5497","article-title":"Bile acids in cholestasis and its treatment","volume":"16","author":"Arab","year":"2017","journal-title":"Ann. Hepatol."},{"key":"10.1016\/j.jep.2022.115330_bib2","first-page":"608","article-title":"Costunolide inhibits ethanol-induced hepatocyte injury and steatosis","volume":"31","author":"Ban","year":"2019","journal-title":"Nat. Prod. Res. Develop."},{"key":"10.1016\/j.jep.2022.115330_bib3","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.biochi.2012.06.022","article-title":"Bile acids: from digestion to cancers","volume":"95","author":"Baptissart","year":"2013","journal-title":"Biochimie"},{"key":"10.1016\/j.jep.2022.115330_bib4","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1016\/j.jhep.2015.02.023","article-title":"New paradigms in the treatment of hepatic cholestasis: from UDCA to FXR, PXR and beyond","volume":"62","author":"Beuers","year":"2015","journal-title":"J. Hepatol."},{"key":"10.1016\/j.jep.2022.115330_bib5","doi-asserted-by":"crossref","DOI":"10.3390\/molecules23092307","article-title":"Quality evaluation of phellodendri chinensis cortex by Fingerprint(-)Chemical pattern recognition","volume":"23","author":"Cao","year":"2018","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2022.115330_bib6","doi-asserted-by":"crossref","DOI":"10.3390\/molecules25040778","article-title":"Adsorption and desorption properties of total flavonoids from oil palm (elaeis guineensis jacq.) mature leaf on macroporous adsorption resins","volume":"25","author":"Che Zain","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2022.115330_bib7","first-page":"8479868","article-title":"Paeoniflorin protects against ANIT-induced cholestatic liver injury in rats via the activation of SIRT1-FXR signaling pathway","volume":"2021","author":"Chen","year":"2021","journal-title":"Evid Based Complement Alternat. Med."},{"key":"10.1016\/j.jep.2022.115330_bib8","doi-asserted-by":"crossref","first-page":"43837","DOI":"10.1038\/srep43837","article-title":"Vlasouliolides A-D, four rare C17\/C15 sesquiterpene lactone dimers with potential anti-inflammatory activity from Vladimiria souliei","volume":"7","author":"Chen","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2022.115330_bib9","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.aca.2008.06.018","article-title":"Quality control and original discrimination of Ganoderma lucidum based on high-performance liquid chromatographic fingerprints and combined chemometrics methods","volume":"623","author":"Chen","year":"2008","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.jep.2022.115330_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.112719","article-title":"Analysis of the similarities and differences between Auclandia and Vladimirae rhizomes by chemical profiling and chemometric analysis","volume":"255","author":"Chen","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2022.115330_bib11","volume":"vol. 1","year":"2020"},{"key":"10.1016\/j.jep.2022.115330_bib12","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1055\/s-0043-120115","article-title":"Inhibition of TNF-alpha-induced inflammation by sesquiterpene lactones from saussurea lappa and semi-synthetic analogues","volume":"84","author":"Choodej","year":"2018","journal-title":"Planta Med."},{"key":"10.1016\/j.jep.2022.115330_bib13","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s12272-017-0990-2","article-title":"Apoptosis induction by alantolactone in breast cancer MDA-MB-231 cells through reactive oxygen species-mediated mitochondrion-dependent pathway","volume":"41","author":"Cui","year":"2018","journal-title":"Arch Pharm. Res. (Seoul)"},{"key":"10.1016\/j.jep.2022.115330_bib14","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1002\/ptr.5299","article-title":"Inhibition of wnt\/beta-catenin pathway by dehydrocostus lactone and costunolide in colon cancer cells","volume":"29","author":"Dong","year":"2015","journal-title":"Phytother Res."},{"key":"10.1016\/j.jep.2022.115330_bib15","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.1017\/S1462399409000994","article-title":"Cholangiocyte proliferation and liver fibrosis","volume":"11","author":"Glaser","year":"2009","journal-title":"Expet Rev. Mol. Med."},{"key":"10.1016\/j.jep.2022.115330_bib16","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1016\/j.bbadis.2017.04.004","article-title":"Expression patterns of nuclear receptors in parenchymal and non-parenchymal mouse liver cells and their modulation in cholestasis","volume":"1863","author":"Gonzalez-Sanchez","year":"2017","journal-title":"Biochim. Biophys. Acta (BBA) - Mol. Basis Dis."},{"key":"10.1016\/j.jep.2022.115330_bib17","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1002\/hep.28965","article-title":"The ascending pathophysiology of cholestatic liver disease","volume":"65","author":"Jansen","year":"2017","journal-title":"Hepatology"},{"key":"10.1016\/j.jep.2022.115330_bib18","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/164_2019_231","article-title":"Targeting FXR in cholestasis","volume":"256","author":"Keitel","year":"2019","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.jep.2022.115330_bib19","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1002\/hep.30966","article-title":"MicroRNA-210 promotes bile acid-induced cholestatic liver injury by targeting mixed-lineage leukemia-4 methyltransferase in mice","volume":"71","author":"Kim","year":"2020","journal-title":"Hepatology"},{"key":"10.1016\/j.jep.2022.115330_bib20","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/j.phymed.2009.03.016","article-title":"Quantitative and chemical fingerprint analysis for quality control of rhizoma Coptidischinensis based on UPLC-PAD combined with chemometrics methods","volume":"16","author":"Kong","year":"2009","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2022.115330_bib21","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.jep.2017.11.018","article-title":"Anti-allergic effects of sesquiterpene lactones from Saussurea costus (Falc.) Lipsch. determined using in vivo and in vitro experiments","volume":"213","author":"Lee","year":"2018","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2022.115330_bib22","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.ijbiomac.2018.11.103","article-title":"Multiple fingerprint profiles and chemometrics analysis of polysaccharides from Sarcandra glabra","volume":"123","author":"Li","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jep.2022.115330_bib23","first-page":"208","article-title":"Anti-HIV lignans from Schisandra micrantha","volume":"3","author":"Li","year":"2005","journal-title":"Zhongguo Tianran Yaowu"},{"key":"10.1016\/j.jep.2022.115330_bib24","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1007\/s00210-019-01657-8","article-title":"Salvianolic acid B protects against ANIT-induced cholestatic liver injury through regulating bile acid transporters and enzymes, and NF-\u03baB\/I\u03baB and MAPK pathways","volume":"392","author":"Li","year":"2019","journal-title":"Naunyn-Schmiedeberg\u2019s Arch. Pharmacol."},{"key":"10.1016\/j.jep.2022.115330_bib25","author":"Li"},{"key":"10.1016\/j.jep.2022.115330_bib26","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1002\/jssc.201000208","article-title":"Pressurized liquid extraction and GC-MS analysis for simultaneous determination of seven components in Cinnamomum cassia and the effect of sample preparation","volume":"33","author":"Lv","year":"2010","journal-title":"J. Separ. Sci."},{"key":"10.1016\/j.jep.2022.115330_bib27","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.tiv.2019.06.002","article-title":"Bile salts regulate CYP7A1 expression and elicit a fibrotic response and abnormal lipid production in 3D liver microtissues","volume":"60","author":"Messner","year":"2019","journal-title":"Toxicol. Vitro"},{"key":"10.1016\/j.jep.2022.115330_bib28","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3390\/ph14050452","article-title":"Kinsenoside alleviates 17alpha-ethinylestradiol-induced cholestatic liver injury in rats by inhibiting inflammatory responses and regulating FXR-mediated bile acid homeostasis","volume":"14","author":"Ming","year":"2021","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.jep.2022.115330_bib29","doi-asserted-by":"crossref","first-page":"3195","DOI":"10.1002\/jssc.201600274","article-title":"Orthogonal separation protocol for the simultaneous preparation of four medically active compounds from Anemarrhenae Rhizoma by sequential polyamide and macroporous resin adsorbent chromatography","volume":"39","author":"Nian","year":"2016","journal-title":"J. Separ. Sci."},{"key":"10.1016\/j.jep.2022.115330_bib31","doi-asserted-by":"crossref","first-page":"41254","DOI":"10.1038\/srep41254","article-title":"Costunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc\/p53 and AKT\/14-3-3 pathway","volume":"7","author":"Peng","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2022.115330_bib32","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1002\/bmc.3167","article-title":"Study on the pharmacokinetics and metabolism of costunolide and dehydrocostus lactone in rats by HPLC-UV and UPLC-Q-TOF\/MS","volume":"28","author":"Peng","year":"2014","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.jep.2022.115330_bib33","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1002\/hep.30348","article-title":"The epidermal growth factor receptor ligand amphiregulin protects from cholestatic liver injury and regulates bile acids synthesis","volume":"4","author":"Santamar\u00eda","year":"2019","journal-title":"Hepatology"},{"key":"10.1016\/j.jep.2022.115330_bib34","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1016\/j.bbadis.2017.06.017","article-title":"Mechanisms of cholangiocyte responses to injury","volume":"1864","author":"Sato","year":"2018","journal-title":"Biochim. Biophys. Acta (BBA) - Mol. Basis Dis."},{"key":"10.1016\/j.jep.2022.115330_bib35","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0107904","article-title":"Inhibition of inflammatory and proliferative responses of human keratinocytes exposed to the sesquiterpene lactones dehydrocostuslactone and costunolide","volume":"9","author":"Scarponi","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2022.115330_bib36","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1002\/hep.30810","article-title":"Direct and indirect effects of fibroblast growth factor (FGF) 15 and FGF19 on liver fibrosis development","volume":"71","author":"Schumacher","year":"2020","journal-title":"Hepatology"},{"key":"10.1016\/j.jep.2022.115330_bib37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073133","article-title":"Circulating liver-specific miR-122 as a novel potential biomarker for diagnosis of cholestatic liver injury","volume":"8","author":"Shifeng","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2022.115330_bib38","first-page":"399","article-title":"Protective effect of dehydrocostus lactone on experimental liver injury in rats","volume":"10","author":"Sun","year":"2015","journal-title":"World Chin. Med."},{"key":"10.1016\/j.jep.2022.115330_bib39","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1016\/0031-9422(90)85430-N","article-title":"Sesquiterpene lactones from vladimiria souliei","volume":"29","author":"Tan","year":"1990","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jep.2022.115330_bib40","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1055\/s-2006-961015","article-title":"Aromatic constituents from viadimiria souliei","volume":"5","author":"Tan","year":"1990","journal-title":"Planta Med."},{"key":"10.1016\/j.jep.2022.115330_bib41","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1002\/hep.28991","article-title":"New therapeutic concepts in bile acid transport and signaling for management of cholestasis","volume":"65","author":"Trauner","year":"2017","journal-title":"Hepatology"},{"key":"10.1016\/j.jep.2022.115330_bib42","first-page":"F1000","volume":"F1000Res 5","author":"Wagner","year":"2016"},{"key":"10.1016\/j.jep.2022.115330_bib43","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.jchromb.2012.03.033","article-title":"Isolation of brefeldin A from Eupenicillium brefeldianum broth using macroporous resin adsorption chromatography","volume":"895\u2013896","author":"Wang","year":"2012","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jep.2022.115330_bib44","first-page":"153","article-title":"Research progress of species of Aucklandia lappa Decne","volume":"1","author":"Wang","year":"2010","journal-title":"J. Chin. Med. Mater."},{"key":"10.1016\/j.jep.2022.115330_bib45","series-title":"Study on Medicinal Ethnobotany and Quality Standards of Vladimiriae Radix","author":"Wang","year":"2004"},{"key":"10.1016\/j.jep.2022.115330_bib46","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1007\/BF01525943","article-title":"\u00fcber ein Aldol aus Isobutyr- und Formaldehyd","volume":"21","author":"Wessely","year":"1900","journal-title":"Monatshefte f\u00fcr Chemie und verwandte Teile anderer Wissenschaften"},{"key":"10.1016\/j.jep.2022.115330_bib47","doi-asserted-by":"crossref","first-page":"111133","DOI":"10.1016\/j.fct.2020.111133","article-title":"Inflammation: cause or consequence of chronic cholestatic liver injury","volume":"137","author":"Woolbright","year":"2020","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jep.2022.115330_bib48","first-page":"76","article-title":"Experimental study on the choleretic and analgesic effects of the alcoholic extracts of Vladimiriae Radix","volume":"9","author":"Xu","year":"2010","journal-title":"JiangSu J. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2022.115330_bib49","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.fct.2018.07.022","article-title":"Metabolomic analysis of cholestatic liver damage in mice","volume":"120","author":"Yang","year":"2018","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jep.2022.115330_bib50","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.drudis.2018.09.007","article-title":"Bile acid homeostasis paradigm and its connotation with cholestatic liver diseases","volume":"24","author":"Yang","year":"2019","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.jep.2022.115330_bib51","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.jbiosc.2010.09.019","article-title":"Preparation of tea catechins using polyamide","volume":"111","author":"Ye","year":"2011","journal-title":"J. Biosci. Bioeng."},{"key":"10.1016\/j.jep.2022.115330_bib52","article-title":"Anti-inflammatory compositions containing Vladinol F","author":"Yoon","year":"2013","journal-title":"KR patent"},{"key":"10.1016\/j.jep.2022.115330_bib53","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1186\/s12906-017-1626-2","article-title":"Comparative studies on the multi-component pharmacokinetics of Aristolochiae Fructus and honey-fried Aristolochiae Fructus extracts after oral administration in rats","volume":"17","author":"Yuan","year":"2017","journal-title":"BMC Compl. Altern."},{"key":"10.1016\/j.jep.2022.115330_bib54","doi-asserted-by":"crossref","first-page":"20559","DOI":"10.1038\/srep20559","article-title":"Bcl2 is a critical regulator of bile acid homeostasis by dictating Shp and lncRNA H19 function","volume":"6","author":"Zhang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2022.115330_bib55","doi-asserted-by":"crossref","first-page":"23","DOI":"10.5582\/bst.2018.01247","article-title":"Anti-inflammatory, anti-oxidative stress and novel therapeutic targets for cholestatic liver injury","volume":"13","author":"Zhang","year":"2019","journal-title":"Biosci. Trends"},{"key":"10.1016\/j.jep.2022.115330_bib56","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.cbi.2016.03.003","article-title":"Evaluation of protective effects of costunolide and dehydrocostuslactone on ethanol-induced gastric ulcer in mice based on multi-pathway regulation","volume":"250","author":"Zheng","year":"2016","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.jep.2022.115330_bib57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jpba.2015.03.010","article-title":"Chemometric analyses for the characterization of raw and processed seeds of Descurainia sophia (L.) based on HPLC fingerprints","volume":"111","author":"Zhou","year":"2015","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jep.2022.115330_bib58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cld.2007.11.010","article-title":"Mechanisms of cholestasis","volume":"12","author":"Zollner","year":"2008","journal-title":"Clin. Liver Dis."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874122003695?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874122003695?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:22:08Z","timestamp":1759944128000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874122003695"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":57,"alternative-id":["S0378874122003695"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2022.115330","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An effective method for preventing cholestatic liver injury of Aucklandiae Radix and Vladimiriae Radix: Inflammation suppression and regulate the expression of bile acid receptors","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2022.115330","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115330"}}