{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T23:16:45Z","timestamp":1784762205810,"version":"3.55.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100013704","name":"CONACYT","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013704","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002850","name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.jep.2022.115344","type":"journal-article","created":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T04:09:44Z","timestamp":1651810184000},"page":"115344","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["A paraguayan toad Rhinella schneideri preparation based on Mbya tradition increases mitochondrial bioenergetics with migrastatic effects dependent on AMPK in breast cancer cells"],"prefix":"10.1016","volume":"294","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9228-5378","authenticated-orcid":false,"given":"Guillermo","family":"Schmeda-Hirschmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8286-8556","authenticated-orcid":false,"given":"Alberto","family":"Burgos-Edwards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonieta","family":"Rojas de Arias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila","family":"L\u00f3pez-Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7024-003X","authenticated-orcid":false,"given":"Charlotte","family":"Palominos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebasti\u00e1n","family":"Fuentes-Retamal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yarela","family":"Herrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2048-4474","authenticated-orcid":false,"given":"Karen","family":"Dubois-Camacho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e9lix A.","family":"Urra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2022.115344_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2019.112049","article-title":"Cytotoxicity and antimitotic activity of Rhinella schneideri and Rhinella marina venoms","volume":"242","author":"Abdelfatah","year":"2019","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2022.115344_bib2","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3389\/fcell.2019.00004","article-title":"Hypoxia-modified cancer cell metabolism","volume":"7","author":"Al Tameemi","year":"2019","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.jep.2022.115344_bib3","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.foodchem.2011.01.003","article-title":"LC-DAD-ESI\/MS analysis of flavonoids and abscisic acid with chemometric approach for the classification of Slovenian honey","volume":"127","author":"Bertoncelj","year":"2011","journal-title":"Food Chem."},{"issue":"19","key":"10.1016\/j.jep.2022.115344_bib4","doi-asserted-by":"crossref","first-page":"3595","DOI":"10.3390\/molecules24193595","article-title":"Chemical profile and multicomponent quantitative analysis for the quality evaluation of toad venom from different origins","volume":"24","author":"Cao","year":"2019","journal-title":"Molecules"},{"issue":"10","key":"10.1016\/j.jep.2022.115344_bib5","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1016\/j.celrep.2016.02.030","article-title":"Selective vulnerability of cancer cells by inhibition of Ca(2+) transfer from endoplasmic reticulum to mitochondria","volume":"14","author":"C\u00e1rdenas","year":"2016","journal-title":"Cell Rep."},{"issue":"1","key":"10.1016\/j.jep.2022.115344_bib6","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s13046-022-02252-1","article-title":"TRPM7 silencing modulates glucose metabolic reprogramming to inhibit the growth of ovarian cancer by enhancing AMPK activation to promote HIF-1\u03b1 degradation","volume":"41","author":"Chen","year":"2022","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"3","key":"10.1016\/j.jep.2022.115344_bib7","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S1470-2045(07)70074-8","article-title":"Triple-negative breast cancer: therapeutic options","volume":"8","author":"Cleator","year":"2007","journal-title":"Lancet Oncol."},{"issue":"10","key":"10.1016\/j.jep.2022.115344_bib8","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.3390\/antiox10101618","article-title":"FRI-1 Is an anti-cancer isoquinolinequinone that inhibits the mitochondrial bioenergetics and blocks metabolic shifts by redox disruption in breast cancer cells","volume":"10","author":"C\u00f3rdova-Delgado","year":"2021","journal-title":"Antioxidants"},{"issue":"1","key":"10.1016\/j.jep.2022.115344_bib9","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s13002-021-00465-w","article-title":"Notes on current Mby\u00e1-Guarani medicinal plant exchanges in southern Brazil","volume":"17","author":"de Andrade","year":"2021","journal-title":"J. Ethnobiol. Ethnomed."},{"issue":"4","key":"10.1016\/j.jep.2022.115344_bib10","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/s10495-011-0573-5","article-title":"Bufadienolide compounds sensitize human breast cancer cells to TRAIL-induced apoptosis via inhibition of STAT3\/Mcl-1 pathway","volume":"16","author":"Dong","year":"2011","journal-title":"Apoptosis"},{"key":"10.1016\/j.jep.2022.115344_bib11","series-title":"Moche Art of Peru","author":"Donnan","year":"1978"},{"issue":"1","key":"10.1016\/j.jep.2022.115344_bib12","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.cmet.2012.12.001","article-title":"AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo","volume":"17","author":"Faubert","year":"2013","journal-title":"Cell Metabol."},{"issue":"7","key":"10.1016\/j.jep.2022.115344_bib13","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1002\/jms.3386","article-title":"Strategies for differentiation of isobaric flavonoids using liquid chromatography coupled to electrospray ionization mass spectrometry","volume":"49","author":"Frid\u00e9n","year":"2014","journal-title":"J. Mass Spectrom."},{"issue":"2","key":"10.1016\/j.jep.2022.115344_bib14","doi-asserted-by":"crossref","first-page":"407","DOI":"10.3390\/cells9020407","article-title":"Complex mitochondrial dysfunction induced by TPP(+)-gentisic acid and mitochondrial translation inhibition by doxycycline evokes synergistic lethality in breast cancer cells","volume":"9","author":"Fuentes-Retamal","year":"2020","journal-title":"Cells"},{"issue":"6","key":"10.1016\/j.jep.2022.115344_bib15","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.molcel.2017.05.032","article-title":"AMPK: mechanisms of cellular energy sensing and restoration of metabolic balance","volume":"66","author":"Garcia","year":"2017","journal-title":"Mol. Cell."},{"issue":"4","key":"10.1016\/j.jep.2022.115344_bib16","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1083\/jcb.201609066","article-title":"AMPK negatively regulates tensin-dependent integrin activity","volume":"216","author":"Georgiadou","year":"2017","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.jep.2022.115344_bib17","doi-asserted-by":"crossref","first-page":"2458","DOI":"10.1021\/jf960952h","article-title":"HPLC-MS\/MS profiling of tryptophan-derived alkaloids in food : identification of tetrahydro-2-carbolinedicarboxylic acids","volume":"45","author":"Gutsche","year":"1997","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jep.2022.115344_bib18","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.toxicon.2019.06.016","article-title":"Buforin IIb induces androgen-independent prostate cancer cells apoptosis though p53 pathway in vitro","volume":"168","author":"Han","year":"2019","journal-title":"Toxicon"},{"issue":"4","key":"10.1016\/j.jep.2022.115344_bib19","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1186\/bcr2889","article-title":"Choosing the right cell line for breast cancer research","volume":"13","author":"Holliday","year":"2011","journal-title":"Breast Cancer Res."},{"issue":"14","key":"10.1016\/j.jep.2022.115344_bib20","doi-asserted-by":"crossref","first-page":"3890","DOI":"10.1021\/acs.jafc.8b07150","article-title":"Large-scale screening of foods for glucose-derived \u03b2-carboline alkaloids by stable isotope dilution LC-MS\/MS","volume":"67","author":"H\u00f6velmann","year":"2019","journal-title":"J. Agric. Food Chem."},{"issue":"12","key":"10.1016\/j.jep.2022.115344_bib21","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.202000011","article-title":"Mass spectrometry-based analysis of urinary biomarkers for dietary tomato intake","volume":"64","author":"H\u00f6velmann","year":"2020","journal-title":"Mol. Nutr. Food Res."},{"issue":"Suppl. 1","key":"10.1016\/j.jep.2022.115344_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1634\/theoncologist.2011-S1-01","article-title":"Triple-negative breast cancer: an unmet medical need","volume":"16","author":"Hudis","year":"2011","journal-title":"Oncol."},{"issue":"5","key":"10.1016\/j.jep.2022.115344_bib23","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1002\/rcm.4436","article-title":"Systematic screening and characterization of novel bufadienolides from toad skin using ultra-performance liquid chromatography\/electrospray ionization quadrupole time-of-flight mass spectrometry","volume":"24","author":"Liu","year":"2010","journal-title":"Rapid Commun. Mass Spectrom."},{"issue":"3","key":"10.1016\/j.jep.2022.115344_bib24","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1159\/000433622","article-title":"Targeted therapies in triple-negative breast cancer","volume":"10","author":"Marm\u00e9","year":"2015","journal-title":"Breast Care"},{"issue":"5","key":"10.1016\/j.jep.2022.115344_bib25","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1002\/rcm.583","article-title":"Characterisation and determination of indole alkaloids in frog-skin secretions by electrospray ionisation ion trap mass spectrometry","volume":"16","author":"McClean","year":"2002","journal-title":"Rapid Commun. Mass Spectrom."},{"issue":"30\u201342","key":"10.1016\/j.jep.2022.115344_bib26","article-title":"The Moche botanical frog","volume":"10","author":"McClelland","year":"2011","journal-title":"Arqueol. Iberoam."},{"issue":"16","key":"10.1016\/j.jep.2022.115344_bib27","doi-asserted-by":"crossref","first-page":"2863","DOI":"10.3390\/molecules24162863","article-title":"Validation of an LC-MS\/MS method for the quantification of caffeine and theobromine using non-matched matrix calibration curve","volume":"24","author":"Mendes","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2022.115344_bib28","article-title":"Stabilization of hypoxia-inducible factor 1\u03b1 by cobalt chloride impairs podocyte morphology and slit-diaphragm function","author":"Nakuluri","year":"2018","journal-title":"J. Cell. Biochem."},{"issue":"45","key":"10.1016\/j.jep.2022.115344_bib29","doi-asserted-by":"crossref","first-page":"19237","DOI":"10.1073\/pnas.1009705107","article-title":"\u03b2-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK)","volume":"107","author":"Oakhill","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"8","key":"10.1016\/j.jep.2022.115344_bib30","doi-asserted-by":"crossref","first-page":"336","DOI":"10.3390\/toxins10080336","article-title":"The development of toad toxins as potential therapeutic agents","volume":"10","author":"Qi","year":"2018","journal-title":"Toxins"},{"issue":"51","key":"10.1016\/j.jep.2022.115344_bib31","doi-asserted-by":"crossref","first-page":"52934","DOI":"10.1074\/jbc.M409574200","article-title":"Biochemical regulation of mammalian AMP-activated protein kinase activity by NAD and NADH","volume":"279","author":"Rafaeloff-Phail","year":"2004","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.jep.2022.115344_bib32","first-page":"79","article-title":"The two faces of reactive oxygen species in cancer","volume":"1","author":"Reczek","year":"2017","journal-title":"Annu. Rev. Cell Biol."},{"key":"10.1016\/j.jep.2022.115344_bib33","series-title":"El sapo en el folklore y en la medicina","first-page":"1","author":"Rosemberg","year":"1951"},{"issue":"5","key":"10.1016\/j.jep.2022.115344_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0128013","article-title":"AMP-activated protein kinase regulates the cell surface proteome and integrin membrane traffic","volume":"10","author":"Ross","year":"2015","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.jep.2022.115344_bib35","doi-asserted-by":"crossref","first-page":"608","DOI":"10.3390\/toxins12090608","article-title":"The parotoid gland secretion from Peruvian toad Rhinella horribilis (Wiegmann, 1833): chemical composition and effect on the proliferation and migration of lung cancer cells","volume":"12","author":"Schmeda-Hirschmann","year":"2020","journal-title":"Toxins"},{"key":"10.1016\/j.jep.2022.115344_bib36","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.jep.2017.01.047","article-title":"The Paraguayan Rhinella toad venom: implications in the traditional medicine and proliferation of breast cancer cells","volume":"199","author":"Schmeda-Hirschmann","year":"2017","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2022.115344_bib37","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.toxicon.2016.09.004","article-title":"Antiproliferative activity and chemical composition of the venom from the Amazonian toad Rhinella marina (Anura: bufonidae)","volume":"121","author":"Schmeda-Hirschmann","year":"2016","journal-title":"Toxicon"},{"issue":"2","key":"10.1016\/j.jep.2022.115344_bib38","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/j.jep.2014.06.025","article-title":"Antiproliferative activity and new argininyl bufadienolide esters from the \"curur\u00fa\" toad Rhinella (Bufo) schneideri","volume":"155","author":"Schmeda-Hirschmann","year":"2014","journal-title":"J. Ethnopharmacol."},{"issue":"11","key":"10.1016\/j.jep.2022.115344_bib39","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.3390\/antiox10111801","article-title":"Tumour microenvironment stress promotes the development of drug resistance","volume":"10","author":"Seebacher","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.jep.2022.115344_bib40","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jfca.2016.08.006","article-title":"Phenolics and abscisic acid identified in acacia honey comparing different SPE cartridges coupled with HPLC-PDA","volume":"53","author":"Sun","year":"2016","journal-title":"J. Food Compos. Anal."},{"key":"10.1016\/j.jep.2022.115344_bib41","doi-asserted-by":"crossref","first-page":"36042","DOI":"10.1038\/srep36042","article-title":"Antioxidant and antitumor activity of a bioactive polyphenolic fraction isolated from the brewing process","volume":"6","author":"Tatullo","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2022.115344_bib42","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.taap.2015.12.005","article-title":"Small structural changes on a hydroquinone scaffold determine the complex I inhibition or uncoupling of tumoral oxidative phosphorylation","volume":"291","author":"Urra","year":"2016","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"17","key":"10.1016\/j.jep.2022.115344_bib43","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.2174\/15680266113139990150","article-title":"Mitochondria: a promising target for anticancer alkaloids","volume":"13","author":"Urra","year":"2013","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.jep.2022.115344_bib44","series-title":"Studies in Natural Products Chemistry","first-page":"1","article-title":"Chapter 1 - recent advances in molecular mechanisms of anticancer natural products that target mitochondrial bioenergetics","author":"Urra","year":"2021"},{"key":"10.1016\/j.jep.2022.115344_bib45","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.751301","article-title":"Extracellular matrix signals as drivers of mitochondrial bioenergetics and metabolic plasticity of cancer cells during metastasis","volume":"9","author":"Urra","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"3","key":"10.1016\/j.jep.2022.115344_bib46","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.taap.2012.12.023","article-title":"An ortho-carbonyl substituted hydroquinone derivative is an anticancer agent that acts by inhibiting mitochondrial bioenergetics and by inducing G\u2082\/M-phase arrest in mammary adenocarcinoma TA3","volume":"267","author":"Urra","year":"2013","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"1","key":"10.1016\/j.jep.2022.115344_bib47","doi-asserted-by":"crossref","first-page":"13190","DOI":"10.1038\/s41598-018-31367-9","article-title":"FR58P1a; a new uncoupler of OXPHOS that inhibits migration in triple-negative breast cancer cells via Sirt1\/AMPK\/\u03b21-integrin pathway","volume":"8","author":"Urra","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2022.115344_bib48","doi-asserted-by":"crossref","first-page":"118","DOI":"10.3389\/fonc.2017.00118","article-title":"The mitochondrial complex(I)ty of cancer","volume":"7","author":"Urra","year":"2017","journal-title":"Front. Oncol."},{"issue":"39","key":"10.1016\/j.jep.2022.115344_bib49","doi-asserted-by":"crossref","first-page":"5998","DOI":"10.2174\/1381612822666160719122626","article-title":"Determinants of anti-cancer effect of mitochondrial electron transport chain inhibitors: bioenergetic profile and metabolic flexibility of cancer cells","volume":"22","author":"Urra","year":"2016","journal-title":"Curr. Pharmaceut. Des."},{"key":"10.1016\/j.jep.2022.115344_bib50","author":"Weiler"},{"issue":"9","key":"10.1016\/j.jep.2022.115344_bib51","first-page":"558","article-title":"High resolution gas chromatography\/mass spectrometric characterization of urinary metabolites of N,N-diethyl-m-toluamide (DEET) in man","volume":"2","author":"Wu","year":"1979","journal-title":"J. Separ. Sci."},{"key":"10.1016\/j.jep.2022.115344_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.pep.2019.105445","article-title":"Identification of angiogenesis-inhibiting peptides from chan su. Protein expr","volume":"163","author":"Xia","year":"2019","journal-title":"Purif"},{"key":"10.1016\/j.jep.2022.115344_bib53","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1002\/hlca.201100038","article-title":"Two new indole alkaloids from the bark of Anthocephalus chinensis","volume":"94","author":"Xu","year":"2011","journal-title":"Helv. Chim. Acta"},{"issue":"13","key":"10.1016\/j.jep.2022.115344_bib54","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1002\/rcm.1989","article-title":"Analysis of bufadienolides in the Chinese drug ChanSu by high-performance liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry","volume":"19","author":"Ye","year":"2005","journal-title":"Rapid Commun. Mass Spectrom."},{"issue":"1","key":"10.1016\/j.jep.2022.115344_bib55","doi-asserted-by":"crossref","first-page":"6453","DOI":"10.1038\/s41598-019-42777-8","article-title":"Revisiting fragmentation reactions of protonated \u03b1-amino acids by high-resolution electrospray ionization tandem mass spectrometry with collision-induced dissociation","volume":"9","author":"Zhang","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2022.115344_bib56","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.jchromb.2015.11.015","article-title":"Separation and characterization of bufadienolides in toad skin using two-dimensional normal-phase liquid chromatography\u00d7reversed-phase liquid chromatography coupled with mass spectrometry","volume":"1026","author":"Zhang","year":"2016","journal-title":"J. Chromatogr., B"},{"issue":"1","key":"10.1016\/j.jep.2022.115344_bib57","doi-asserted-by":"crossref","first-page":"86","DOI":"10.3390\/molecules24010086","article-title":"Comparative analysis of hydrophilic ingredients in toad skin and toad venom using the UHPLC-HR-MS\/MS and UPLC-QqQ-MS\/MS methods together with the anti-inflammatory evaluation of indolealkylamines","volume":"24","author":"Zhang","year":"2018","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2022.115344_bib58","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.ijms.2012.10.011","article-title":"Fragmentation pathway studies of several plant hormones using an electrospray ionization-quadrupole\/time-of-flight mass spectrometer","volume":"335","author":"Zhao","year":"2013","journal-title":"Int. J. Mass Spectrom."},{"issue":"8","key":"10.1016\/j.jep.2022.115344_bib59","doi-asserted-by":"crossref","first-page":"9755","DOI":"10.3390\/molecules18089755","article-title":"Characterization of nucleosides and nucleobases in natural Cordyceps by HILIC-ESI\/TOF\/MS and HILIC-ESI\/MS","volume":"18","author":"Zhao","year":"2013","journal-title":"Molecules"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037887412200383X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037887412200383X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:23:44Z","timestamp":1759944224000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S037887412200383X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":59,"alternative-id":["S037887412200383X"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2022.115344","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A paraguayan toad Rhinella schneideri preparation based on Mbya tradition increases mitochondrial bioenergetics with migrastatic effects dependent on AMPK in breast cancer cells","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2022.115344","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115344"}}