{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T17:31:50Z","timestamp":1778866310862,"version":"3.51.4"},"reference-count":88,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.jep.2022.115636","type":"journal-article","created":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T09:13:39Z","timestamp":1661246019000},"page":"115636","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Phytochemical screening, cytotoxicity assessment and evaluation of in vitro antiplasmodial and in vivo antimalarial activities of Mentha spicata L. methanolic leaf extract"],"prefix":"10.1016","volume":"298","author":[{"given":"Aditi","family":"Chatterjee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nalini","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wahengbam Kabita","family":"Chanu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4910-310X","authenticated-orcid":false,"given":"Chingakham Brajakishor","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1243-0369","authenticated-orcid":false,"given":"Viswanathan Arun","family":"Nagaraj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"15","key":"10.1016\/j.jep.2022.115636_bib1","doi-asserted-by":"crossref","first-page":"5054","DOI":"10.3390\/app10155054","article-title":"Green synthesized ZnO nanoparticles mediated by Mentha Spicata extract induce plant systemic resistance against Tobacco mosaic virus","volume":"10","author":"Abdelkhalek","year":"2020","journal-title":"Appl. Sci."},{"issue":"21","key":"10.1016\/j.jep.2022.115636_bib2","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.5897\/AJMR12.1875","article-title":"Antimicrobial activity of Palestinian medicinal plants against acne-inducing bacteria","volume":"7","author":"Ali-Shtayeh","year":"2013","journal-title":"Afr. J. Microbiol. Res."},{"issue":"9","key":"10.1016\/j.jep.2022.115636_bib3","doi-asserted-by":"crossref","first-page":"381","DOI":"10.31989\/ffhd.v4i9.149","article-title":"In-vitro screening of acetylcholinesterase inhibitory activity of extracts from Palestinian indigenous flora in relation to the treatment of Alzheimer's disease","volume":"4","author":"Ali-Shtayeh","year":"2014","journal-title":"Funct. Foods Health Dis."},{"issue":"6","key":"10.1016\/j.jep.2022.115636_bib4","first-page":"806","article-title":"Biosynthesis of silver nanoparticles with Mentha spicata against Aspergillus niger","volume":"14","author":"Alkfaji","year":"2020","journal-title":"Drug Invent. Today"},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1475-2875-11-316","article-title":"The global pipeline of new medicines for the control and elimination of malaria","volume":"11","author":"Anthony","year":"2012","journal-title":"Malar. J."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib6","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.etap.2008.02.008","article-title":"Anti-inflammatory activity of four solvent fractions of ethanol extract of Mentha spicata L. investigated on acute and chronic inflammation induced rats","volume":"26","author":"Arumugam","year":"2008","journal-title":"Environ. Toxicol. Pharmacol."},{"issue":"7","key":"10.1016\/j.jep.2022.115636_bib7","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1007\/s00044-009-9221-9","article-title":"Superoxide radical scavenging and antibacterial activities of different fractions of ethanol extract of Mentha spicata (L.)","volume":"19","author":"Arumugam","year":"2010","journal-title":"Med. Chem. Res."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib8","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1080\/10942910802144329","article-title":"Antioxidant and cytotoxic activities of lipophilic and hydrophilic fractions of Mentha spicata L.(Lamiaceae)","volume":"13","author":"Arumugam","year":"2010","journal-title":"Int. J. Food Prop."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib9","first-page":"1","article-title":"In vivo antimalarial activity of the crude leaf extract and solvent fractions of Croton macrostachyus Hocsht.(Euphorbiaceae) against Plasmodium berghei in mice","volume":"14","author":"Bantie","year":"2014","journal-title":"BMC Compl. Alternative Med."},{"issue":"4","key":"10.1016\/j.jep.2022.115636_bib10","first-page":"25","article-title":"General techniques involved in phytochemical analysis","volume":"2","author":"Banu","year":"2015","journal-title":"Int. J. Adv. Res. Comput. Sci."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib11","first-page":"1","article-title":"Chemical composition, antioxidant, antimicrobial and Antiproliferative activities of essential oil of Mentha spicata L. (Lamiaceae) from Algerian Saharan atlas","volume":"18","author":"Bardaweel","year":"2018","journal-title":"BMC Compl. Alternative Med."},{"key":"10.1016\/j.jep.2022.115636_bib12","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.indcrop.2015.07.004","article-title":"Chemical composition and functional properties of essential oils from Mentha species","volume":"76","author":"Barros","year":"2015","journal-title":"Ind. Crop. Prod."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib13","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1078\/0065-1281-00534","article-title":"Hemolysis of human erythrocytes with saponin affects the membrane structure","volume":"102","author":"Baumann","year":"2000","journal-title":"Acta Histochem."},{"issue":"3","key":"10.1016\/j.jep.2022.115636_bib14","article-title":"Effect of essential oils of Mentha spicata L. and Melaleuca alternifolia Cheel on the midgut of Podisus nigrispinus (Dallas)(Hemiptera:Pentatomidae)","volume":"122","author":"Braga","year":"2020","journal-title":"Acta Histochem."},{"issue":"3","key":"10.1016\/j.jep.2022.115636_bib15","doi-asserted-by":"crossref","first-page":"578","DOI":"10.15835\/nsb12310758","article-title":"Beneficial effect of Mentha spicata essential oil on lead and manganese induced nephrotoxicity and oxidative damage in rat kidney","volume":"12","author":"Brahmi","year":"2020","journal-title":"Not. Sci. Biol."},{"issue":"4","key":"10.1016\/j.jep.2022.115636_bib16","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1007\/s00436-011-2250-6","article-title":"Screening of antiplasmodial efficacy of Ajuga bracteosa Wall ex","volume":"108","author":"Chandel","year":"2011","journal-title":"Benth. Parasitol Res."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib17","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.actatropica.2005.09.004","article-title":"In vitro antimalarial activity of flavonoid derivatives dehydrosilybin and 8-(1;1)-DMA-kaempferide","volume":"97","author":"de Monbrison","year":"2006","journal-title":"Acta Trop."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib18","article-title":"In vivo anti-malarial activities of Clerodendrum myricoides, Dodonea angustifolia and Aloe debrana against Plasmodium berghei","volume":"24","author":"Deressa","year":"2010","journal-title":"Ethiop. J. Health Dev."},{"issue":"2","key":"10.1016\/j.jep.2022.115636_bib19","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.jep.2010.05.012","article-title":"Antispasmodic effect of Mentha piperita essential oil on tracheal smooth muscle of rats","volume":"130","author":"de Sousa","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2022.115636_bib20","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.indcrop.2015.07.004","article-title":"Chemical composition and functional properties of essential oils from Mentha species","volume":"76","author":"de Sousa Barros","year":"2015","journal-title":"Ind. Crop. Prod."},{"issue":"6","key":"10.1016\/j.jep.2022.115636_bib21","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1128\/AAC.16.6.710","article-title":"Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique","volume":"16","author":"Desjardins","year":"1979","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jep.2022.115636_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.actatropica.2021.106040","article-title":"Defeating malaria in the North-East region: the fore runner for malaria elimination in India","volume":"222","author":"Dev","year":"2021","journal-title":"Acta Trop."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib23","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jep.2011.04.024","article-title":"Antiprotozoal activities of traditional medicinal plants from the Garhwal region of North West Himalaya, India","volume":"136","author":"Dua","year":"2011","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2022.115636_bib24","article-title":"Medicinal uses, phytochemistry, pharmacology, and toxicology of Mentha spicata","volume":"32","author":"El Menyiy","year":"2022","journal-title":"Evid-Based Compl. Alternative Med."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib25","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1080\/0972060X.2021.1896976","article-title":"Essential oil Compositionand phytochemical properties from leaves of Felty Germander (Teucrium polium L.) and Spearmint (Mentha spicata L.)","volume":"24","author":"Farahbakhsh","year":"2021","journal-title":"J. Essent. Oil-Bear. Plants."},{"key":"10.1016\/j.jep.2022.115636_bib26","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.indcrop.2015.04.038","article-title":"Phenolic composition, in vitro antioxidant effects and tyrosinase inhibitory activity of three Algerian Mentha species: M. spicata (L.), M. pulegium (L.) and M. rotundifolia (L.), Huds (Lamiaceae)","volume":"74","author":"Fatiha","year":"2015","journal-title":"Ind. Crop. Prod."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1475-2875-10-S1-S1","article-title":"A call for using natural compounds in the development of new antimalarial treatments\u2013an introduction","volume":"10","author":"Ginsburg","year":"2011","journal-title":"Malar. J."},{"issue":"5","key":"10.1016\/j.jep.2022.115636_bib28","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1007\/s00436-011-2731-7","article-title":"Chemical composition and larvicidal activity of essential oil from Mentha spicata (Linn.) against three mosquito species","volume":"110","author":"Govindarajan","year":"2012","journal-title":"Parasitol. Res."},{"issue":"4","key":"10.1016\/j.jep.2022.115636_bib29","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1093\/jac\/30.4.417","article-title":"The quinine connection","volume":"30","author":"Greenwood","year":"1992","journal-title":"J. Antimicrob. Chemother."},{"issue":"3","key":"10.1016\/j.jep.2022.115636_bib30","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/BF03175551","article-title":"Comparison of chemical composition and antimicrobial activities of Mentha longifolia L. ssp. longifolia essential oil from two Tunisian localities (Gabes and Sidi Bouzid)","volume":"58","author":"Hajlaoui","year":"2008","journal-title":"Ann. Microbiol."},{"issue":"12","key":"10.1016\/j.jep.2022.115636_bib31","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.1007\/s11274-009-0130-3","article-title":"Biological activities of the essential oils and methanol extract of two cultivated mint species (Mentha longifolia and Mentha pulegium) used in the Tunisian folkloric medicine","volume":"25","author":"Hajlaoui","year":"2009","journal-title":"World J. Microbiol. Biotechnol."},{"issue":"7","key":"10.1016\/j.jep.2022.115636_bib32","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1002\/ptr.1231","article-title":"Evaluation of the antimalarial properties and standardization of tablets of Azadirachta indica (Meliaceae) in mice","volume":"17","author":"Isah","year":"2003","journal-title":"Phytother Res."},{"key":"10.1016\/j.jep.2022.115636_bib33","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/8426752","article-title":"Antiobesity and antioxidant potentials of selected palestinian medicinal plants","author":"Jamous","year":"2018","journal-title":"Evid. Based Compl. Altern. Med."},{"issue":"2","key":"10.1016\/j.jep.2022.115636_bib34","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.jep.2006.07.022","article-title":"Mints\u201d, smells and traditional uses in Thessaloniki (Greece) and other Mediterranean countries","volume":"109","author":"Karousou","year":"2007","journal-title":"J. Ethnomapharmacol."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib35","first-page":"15","article-title":"Spearmint (Mentha spicata L.) essential oil from tipaza (Algeria): in vivo anti-inflammatory and analgesic activities in experimental animal models","volume":"90","author":"Kehili","year":"2020","journal-title":"Acta Pharm. Hung."},{"issue":"4","key":"10.1016\/j.jep.2022.115636_bib36","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S2221-1691(13)60060-X","article-title":"Bioavailability enhancers of herbal origin: an overview","volume":"3","author":"Kesarwani","year":"2013","journal-title":"Asian Pac. J. Trop. Biomed."},{"issue":"4703","key":"10.1016\/j.jep.2022.115636_bib37","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1126\/science.3887571","article-title":"Qinghaosu (artemisinin): an antimalarial drug from China","volume":"228","author":"Klayman","year":"1985","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.jep.2022.115636_bib38","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.bse.2005.08.002","article-title":"Antimalarial abietane diterpene from Fuerstia africana TCE Fries","volume":"34","author":"Koch","year":"2006","journal-title":"Biochem. Systemat. Ecol."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib39","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/jaoac\/94.1.43","article-title":"Determination of polyphenols in Mentha longifolia and M. piperita field-grown and in vitro plant samples using UPLC-TQ-MS","volume":"94","author":"Krzyzanowska","year":"2011","journal-title":"J. AOAC Int."},{"issue":"1\u20134","key":"10.1016\/j.jep.2022.115636_bib40","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1002\/biof.5520220117","article-title":"Anticancer and radioprotective potentials of Mentha piperita","volume":"22","author":"Kumar","year":"2004","journal-title":"Biofactors"},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib41","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.indcrop.2011.02.019","article-title":"Insecticidal properties of Mentha species: a review","volume":"34","author":"Kumar","year":"2011","journal-title":"Ind. Crop. Prod."},{"key":"10.1016\/j.jep.2022.115636_bib42","article-title":"Synchronization of Plasmodium falciparum erythrocytic stages in culture","volume":"418\u2013420","author":"Lambros","year":"1979","journal-title":"J. Parasitol."},{"key":"10.1016\/j.jep.2022.115636_bib43","series-title":"The genus Mentha","first-page":"556","author":"Lawrence","year":"2007"},{"key":"10.1016\/j.jep.2022.115636_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ctcp.2016.11.001","article-title":"Mentha spicata as natural analgesia for treatment of pain in osteoarthritis patients","volume":"26","author":"Mahboubi","year":"2017","journal-title":"Compl. Ther. Clin. Pract."},{"key":"10.1016\/j.jep.2022.115636_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114266","article-title":"The traditional uses, Phytochemistry and pharmacology of Spearmint (Mentha spicata L.): a review","volume":"278","author":"Mahendran","year":"2021","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib46","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.jep.2011.11.006","article-title":"Ethnobotanical study of antimalarial plants in Shinile District, Somali Region, Ethiopia and in vivo evaluation of selected ones against Plasmodium berghei","volume":"139","author":"Mesfin","year":"2012","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2022.115636_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.indcrop.2020.112944","article-title":"Mentha spicata essential oil nanoformulation and its larvicidal application against Culex pipiens and Musca domestica","volume":"157","author":"Mohafrash","year":"2020","journal-title":"Ind. Crop. Prod."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib48","first-page":"308","article-title":"Hydrogel films of methanolic Mentha piperita extract and silver nanoparticles enhance wound healing in rats with diabetes TypeI","volume":"16","author":"Mojally","year":"2022","journal-title":"J. TaibahUniv. Sci."},{"issue":"6","key":"10.1016\/j.jep.2022.115636_bib49","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1055\/s-0034-1368322","article-title":"In vitro and in vivo antiplasmodial activity of three Rwandan medicinal plants and identification of their active compounds","volume":"80","author":"Muganga","year":"2014","journal-title":"Planta Med."},{"key":"10.1016\/j.jep.2022.115636_bib50","article-title":"Antimalarial activity and biochemical effects of saponin-rich extract of Dianthus basuticus Burtt Davy in Plasmodiumberghei-infectedmice","volume":"1\u201311","author":"Nafiu","year":"2021","journal-title":"Adv. Trad. Med."},{"key":"10.1016\/j.jep.2022.115636_bib51","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1051\/parasite\/2014033","article-title":"Activity of Ocimum basilicum, Ocimum canum, and Cymbopogon citratus essential oils against Plasmodium falciparum and mature-stage larvae of Anopheles funestus ss","volume":"21","author":"Ntonga","year":"2014","journal-title":"Parasite"},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib52","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-022-14391-8","article-title":"In vitro and in vivo antimalarial activity and chemical profiling of sugarcane leaves","volume":"12","author":"Okokon","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2022.115636_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2019.112334","article-title":"Potential antimalarial activity of Coccinia barteri leaf extract and solvent fractions against Plasmodium berghei infected mice","volume":"248","author":"Orabueze","year":"2020","journal-title":"J. Ethnopharmacol."},{"issue":"3","key":"10.1016\/j.jep.2022.115636_bib54","first-page":"239","article-title":"Antimicrobial and antiviral effects of essential oils from selected Umbelliferae and Labiatae plants and individual essential oil components","volume":"36","author":"Orhan","year":"2012","journal-title":"Turk. J. Biol."},{"issue":"3","key":"10.1016\/j.jep.2022.115636_bib55","first-page":"4503","article-title":"Effect of the extraction method on the content of phenolic compounds and the antioxidant and antibacterial potential of Mentha spicata L","volume":"77","author":"Oueslati","year":"2020","journal-title":"J. New Sci."},{"issue":"2","key":"10.1016\/j.jep.2022.115636_bib56","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0022-474X(01)00007-8","article-title":"Repellent, toxic and reproduction inhibitory effects of essential oil vapours on Acanthoscelides obtectus (Say) (Coleoptera: Bruchidae)","volume":"38","author":"Papachristos","year":"2002","journal-title":"J. Stored Prod. Res."},{"issue":"3","key":"10.1016\/j.jep.2022.115636_bib57","first-page":"235","article-title":"Potential pharmacological and toxicological basis of the essential oil from Mentha spp","volume":"30","author":"Peixoto","year":"2009","journal-title":"Rev Ci\u00eanc Farm B\u00e1sica Apl."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib58","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3390\/pharmaceutics11010033","article-title":"Drug bioavailability enhancing agents of natural origin (bioenhancers) that modulate drug membrane permeation and pre-systemic metabolism","volume":"11","author":"Peterson","year":"2019","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.jep.2022.115636_bib59","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1080\/00034983.1975.11686997","article-title":"The four-day suppressive in vivo antimalarial test","volume":"69","author":"Peters","year":"1975","journal-title":"Ann. Trop. Med. Parasitol."},{"issue":"6","key":"10.1016\/j.jep.2022.115636_bib60","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1080\/14786419.2019.1610755","article-title":"Antifungal activity of essential oil from Mentha spicata L. and Mentha pulegium L. growing wild in Sardinia island (Italy)","volume":"35","author":"Piras","year":"2021","journal-title":"Nat. Prod. Res."},{"issue":"5","key":"10.1016\/j.jep.2022.115636_bib61","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1055\/s-2007-967167","article-title":"Antioxidant, antimalarial and antimicrobial activities of tannin-rich fractions, ellagitannins and phenolic acids from Punica granatum L","volume":"53","author":"Reddy","year":"2007","journal-title":"Planta Med."},{"key":"10.1016\/j.jep.2022.115636_bib62","first-page":"209","article-title":"The antimalarial activity of some quinoline esters","volume":"84","author":"Ryley","year":"1995","journal-title":"Ann. Trop. Med. Parasitol."},{"issue":"4","key":"10.1016\/j.jep.2022.115636_bib63","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1007\/s10787-019-00650-0","article-title":"Nicotine-induced oxidative stress, testis injury, AChE inhibition and brain damage alleviated by Mentha spicata","volume":"28","author":"Saad","year":"2020","journal-title":"Inflammopharmacology"},{"issue":"7","key":"10.1016\/j.jep.2022.115636_bib64","first-page":"22","article-title":"Common spices plant used as medicine by the Tangkhul tribe of Ukhrul district, Manipur, India","volume":"6","author":"Salam","year":"2016","journal-title":"Int. J. Sci. Res."},{"key":"10.1016\/j.jep.2022.115636_bib65","first-page":"229","article-title":"Mentha piperita (Linn.) leaf extract provides protection against radiation induced chromosomal damage in bone marrow of mice","volume":"4","author":"Samarth","year":"2003","journal-title":"Indian J. Exp. Biol."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib66","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.jep.2010.04.006","article-title":"In vivo antimalarial evaluation of Gomphostenins","volume":"130","author":"Sathe","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2022.115636_bib67","first-page":"1314","article-title":"Antimalarial agents from plant sources","volume":"85","author":"Saxena","year":"2003","journal-title":"Curr. Sci."},{"key":"10.1016\/j.jep.2022.115636_bib68","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.indcrop.2013.07.007","article-title":"Antioxidant and antibacterial activities and composition of Brazilian spearmint (Mentha spicata L.)","volume":"50","author":"Scherer","year":"2013","journal-title":"Ind. Crops Prod."},{"issue":"2","key":"10.1016\/j.jep.2022.115636_bib69","doi-asserted-by":"crossref","first-page":"603","DOI":"10.22271\/chemi.2020.v8.i2i.8834","article-title":"Qualitative tests for preliminary phytochemical screening: an overview","volume":"8","author":"Shaikh","year":"2020","journal-title":"Int. J. Chem. Stud."},{"issue":"4","key":"10.1016\/j.jep.2022.115636_bib70","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/j.1750-3841.2010.01603.x","article-title":"Polyphenolic acids from mint (the aerial of Mentha haplocalyx Briq.) with DPPH radical scavenging activity","volume":"75","author":"She","year":"2010","journal-title":"J. Food Sci."},{"issue":"5","key":"10.1016\/j.jep.2022.115636_bib71","first-page":"606","article-title":"Ethnopharmacological survey of medicinal plants in Andro Village in Manipur (India)","volume":"4","author":"Singh","year":"2018","journal-title":"Res. J. Life Sci."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib72","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12936-019-3060-z","article-title":"In vitro anti-malarial efficacy of chalcones: cytotoxicity profile, mechanism of action and their effect on erythrocytes","volume":"18","author":"Sinha","year":"2019","journal-title":"Malar. J."},{"issue":"8","key":"10.1016\/j.jep.2022.115636_bib73","doi-asserted-by":"crossref","first-page":"14402","DOI":"10.3390\/molecules200814402","article-title":"Mentha spicata essential oil: chemical composition, antioxidant and antibacterial activities against planktonic and biofilm cultures of Vibrio spp. strains","volume":"20","author":"Snoussi","year":"2015","journal-title":"Molecules"},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib74","first-page":"1","article-title":"Phytochemical analysis of local spearmint (Mentha spicata) leaves and detection of the antimicrobial activity of its oil","volume":"1","author":"Sulieman","year":"2011","journal-title":"J. Microbiol."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib75","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12936-019-3026-1","article-title":"Antiplasmodial natural products: an update","volume":"18","author":"Tajuddeen","year":"2019","journal-title":"Malar. J."},{"issue":"1","key":"10.1016\/j.jep.2022.115636_bib76","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1055\/s-2005-837745","article-title":"In vivo antimalarial activity of essential oils from Cymbopogon citratus and Ocimum gratissimum on mice infected with Plasmodium berghei","volume":"71","author":"Tchoumbougnang","year":"2005","journal-title":"Planta Med."},{"key":"10.1016\/j.jep.2022.115636_bib77","first-page":"290","article-title":"Antiemetic activity of volatile oil from Mentha spicata and Mentha piperita in chemotherapy induced nausea and vomiting","volume":"7","author":"Tayarani-Najaran","year":"2013","journal-title":"Ecancermedicalscience"},{"key":"10.1016\/j.jep.2022.115636_bib78","series-title":"The OECD guidelines for testing of chemicals. Test No. 425., acute oral toxicity: up-and-down procedure","year":"2008"},{"issue":"16","key":"10.1016\/j.jep.2022.115636_bib79","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1111\/febs.14127","article-title":"Combating multidrug resistant Plasmodium falciparum malaria","volume":"284","author":"Thu","year":"2017","journal-title":"FEBS J."},{"issue":"7","key":"10.1016\/j.jep.2022.115636_bib80","first-page":"324","article-title":"Antimalarial activity of Lamiaceae family plants","volume":"11","author":"Tjitraresmi","year":"2020","journal-title":"Sys. Rev. Pharm."},{"issue":"4254","key":"10.1016\/j.jep.2022.115636_bib81","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1126\/science.781840","article-title":"Human malaria parasites in continuous culture","volume":"193","author":"Trager","year":"1976","journal-title":"Science"},{"key":"10.1016\/j.jep.2022.115636_bib82","article-title":"Alkaloids from plants with antimalarial activity: a review of recent studies","volume":"17","author":"Uzor","year":"2020","journal-title":"Evid. Based Compl. Alternat. Med."},{"issue":"12","key":"10.1016\/j.jep.2022.115636_bib83","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/S1473-3099(13)70252-4","article-title":"Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies","volume":"13","author":"Witkowski","year":"2013","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.jep.2022.115636_bib84","series-title":"World Malaria Report","author":"World Health Organization","year":"2021"},{"issue":"4","key":"10.1016\/j.jep.2022.115636_bib85","doi-asserted-by":"crossref","first-page":"854","DOI":"10.9734\/BJPR\/2013\/4640","article-title":"Analgesic, anti-inflammatory and antipyretic effect of Mentha spicata (Spearmint)","volume":"3","author":"Yousuf","year":"2013","journal-title":"Br. J. Pharmaceut. Res."},{"issue":"6","key":"10.1016\/j.jep.2022.115636_bib86","first-page":"2440","article-title":"In vitro antimicrobial activity, phytochemical analysis and total phenolic content of essential oil from Mentha spicata and Mentha piperita","volume":"22","author":"Zaidi","year":"2015","journal-title":"Int. Food Res. J."},{"issue":"3","key":"10.1016\/j.jep.2022.115636_bib87","first-page":"274","article-title":"Anti-bacterial effect of Mentha spicata L. essential oil on eight standard species of gastrointestinal pathogens","volume":"21","author":"Zare Bidaki","year":"2014","journal-title":"J. Birjand Univ. Med. Sci."},{"issue":"21","key":"10.1016\/j.jep.2022.115636_bib88","doi-asserted-by":"crossref","first-page":"11400","DOI":"10.1021\/jf1022077","article-title":"Yield, content, and composition of peppermint and spearmints as a function of harvesting time and drying","volume":"58","author":"Zheljazkov","year":"2010","journal-title":"J. Agric. Food Chem."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874122006754?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874122006754?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:33:26Z","timestamp":1759944806000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874122006754"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":88,"alternative-id":["S0378874122006754"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2022.115636","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Phytochemical screening, cytotoxicity assessment and evaluation of in vitro antiplasmodial and in vivo antimalarial activities of Mentha spicata L. methanolic leaf extract","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2022.115636","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115636"}}