{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T02:44:16Z","timestamp":1792550656682,"version":"4.5.0"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.jep.2022.115790","type":"journal-article","created":{"date-parts":[[2022,10,5]],"date-time":"2022-10-05T19:47:14Z","timestamp":1664999234000},"page":"115790","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Coriolus versicolor and its bioactive molecule are potential immunomodulators against cancer cell metastasis via inactivation of MAPK pathway"],"prefix":"10.1016","volume":"301","author":[{"given":"Cindy Lai-Hung","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley Chi-Chung","family":"Chik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan Sik-Yin","family":"Lau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Godfrey Chi-Fung","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2022.115790_bib1","article-title":"Potential of mushroom compounds as immunomodulators in cancer immunotherapy: a review, evid. Based complement","author":"Ayeka","year":"2018","journal-title":"Alternat. Med."},{"issue":"2","key":"10.1016\/j.jep.2022.115790_bib2","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S1359-6101(01)00020-X","article-title":"Tumor necrosis factor or tumor promoting factor?","volume":"13","author":"Balkwill","year":"2002","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.jep.2022.115790_bib3","doi-asserted-by":"crossref","DOI":"10.3402\/fnr.v60.29953","article-title":"A safety assessment of Coriolus versicolor biomass as a food supplement","volume":"60","author":"Barros","year":"2016","journal-title":"Food Nutr. Res."},{"issue":"4","key":"10.1016\/j.jep.2022.115790_bib4","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s00109-015-1269-z","article-title":"Invasion and metastasis--recent advances and future challenges","volume":"93","author":"Chambers","year":"2015","journal-title":"J. Mol. Med. (Berl.)"},{"issue":"24","key":"10.1016\/j.jep.2022.115790_bib5","doi-asserted-by":"crossref","first-page":"9228","DOI":"10.1158\/0008-5472.CAN-09-1950","article-title":"Extracellular signal-regulated kinase signaling pathway regulates breast cancer cell migration by maintaining slug expression","volume":"69","author":"Chen","year":"2009","journal-title":"Cancer Res."},{"issue":"6","key":"10.1016\/j.jep.2022.115790_bib6","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1002\/ijc.22729","article-title":"Interferon-gamma regulation of TNFalpha-induced matrix metalloproteinase 3 expression and migration of human glioma T98G cells","volume":"121","author":"Cheng","year":"2007","journal-title":"Int. J. Cancer"},{"issue":"11","key":"10.1016\/j.jep.2022.115790_bib7","doi-asserted-by":"crossref","first-page":"7218","DOI":"10.4049\/jimmunol.175.11.7218","article-title":"A role for double-stranded RNA-activated protein kinase PKR in Mycobacterium-induced cytokine expression","volume":"175","author":"Cheung","year":"2005","journal-title":"J. Immunol."},{"issue":"9","key":"10.1016\/j.jep.2022.115790_bib8","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1177\/009127000204200904","article-title":"Coriolus versicolor: a medicinal mushroom with promising immunotherapeutic values","volume":"42","author":"Chu","year":"2002","journal-title":"J. Clin. Pharmacol."},{"issue":"7","key":"10.1016\/j.jep.2022.115790_bib9","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/nrc.2016.52","article-title":"Neutrophils in cancer: neutral no more","volume":"16","author":"Coffelt","year":"2016","journal-title":"Nat. Rev. Cancer"},{"issue":"2","key":"10.1016\/j.jep.2022.115790_bib10","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0734-9750(03)00002-8","article-title":"Polysaccharopeptides of Coriolus versicolor: physiological activity, uses, and production","volume":"21","author":"Cui","year":"2003","journal-title":"Biotechnol. Adv."},{"issue":"22","key":"10.1016\/j.jep.2022.115790_bib11","doi-asserted-by":"crossref","first-page":"3279","DOI":"10.1038\/sj.onc.1210421","article-title":"MAP kinase signalling pathways in cancer","volume":"26","author":"Dhillon","year":"2007","journal-title":"Oncogene"},{"key":"10.1016\/j.jep.2022.115790_bib12","doi-asserted-by":"crossref","first-page":"878","DOI":"10.3389\/fimmu.2017.00878","article-title":"Role of type I and II interferons in colorectal cancer and melanoma","volume":"8","author":"Di Franco","year":"2017","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.jep.2022.115790_bib13","doi-asserted-by":"crossref","first-page":"78","DOI":"10.2174\/187221312798889310","article-title":"Efficacy of Yun Zhi (Coriolus versicolor) on survival in cancer patients: systematic review and meta-analysis","volume":"6","author":"Eliza","year":"2012","journal-title":"Recent Pat. Inflamm. Allergy Drug Discov."},{"issue":"5","key":"10.1016\/j.jep.2022.115790_bib14","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1038\/nrc1075","article-title":"Tumour-cell invasion and migration: diversity and escape mechanisms","volume":"3","author":"Friedl","year":"2003","journal-title":"Nat. Rev. Cancer"},{"issue":"8","key":"10.1016\/j.jep.2022.115790_bib15","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.4049\/jimmunol.141.8.2635","article-title":"Anti-proliferative effect of IFN-gamma in immune regulation. II. IFN-gamma inhibits the proliferation of murine bone marrow cells stimulated with IL-3, IL-4, or granulocyte-macrophage colony-stimulating factor","volume":"141","author":"Gajewski","year":"1988","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.jep.2022.115790_bib16","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s12885-017-3896-y","article-title":"Inhibition of p38 MAPK activity leads to cell type-specific effects on the molecular circadian clock and time-dependent reduction of glioma cell invasiveness","volume":"18","author":"Goldsmith","year":"2018","journal-title":"BMC Cancer"},{"issue":"5","key":"10.1016\/j.jep.2022.115790_bib17","doi-asserted-by":"crossref","first-page":"67","DOI":"10.5306\/wjco.v3.i5.67","article-title":"A complete compilation of matrix metalloproteinase expression in human malignant gliomas","volume":"3","author":"Hagemann","year":"2012","journal-title":"World J. Clin. Oncol."},{"issue":"3","key":"10.1016\/j.jep.2022.115790_bib18","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1097\/MPA.0b013e318238379d","article-title":"Biological and prognostic relevance of mitogen-activated protein kinases in pancreatic adenocarcinoma","volume":"41","author":"Handra-Luca","year":"2012","journal-title":"Pancreas"},{"issue":"3","key":"10.1016\/j.jep.2022.115790_bib19","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/j.jep.2011.07.007","article-title":"Acute and subchronic oral toxicity of Coriolus versicolor standardized water extract in Sprague-Dawley rats","volume":"137","author":"Hor","year":"2011","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.jep.2022.115790_bib20","doi-asserted-by":"crossref","first-page":"669","DOI":"10.3892\/mmr.2013.1542","article-title":"Immunomodulatory effects of polysaccharopeptide in immunosuppressed mice induced by cyclophosphamide","volume":"8","author":"Huang","year":"2013","journal-title":"Mol. Med. Rep."},{"issue":"115","key":"10.1016\/j.jep.2022.115790_bib21","first-page":"889","article-title":"Norepinephrine stimulates pancreatic cancer cell proliferation, migration and invasion via \u03b2-adrenergic receptor-dependent activation of P38\/MAPK pathway","volume":"59","author":"Huang","year":"2012","journal-title":"Hepato-Gastroenterology"},{"issue":"23","key":"10.1016\/j.jep.2022.115790_bib22","doi-asserted-by":"crossref","first-page":"9063","DOI":"10.3390\/ijms21239063","article-title":"Extract from the Coriolus versicolor fungus as an anti-inflammatory agent with cytotoxic properties against endothelial cells and breast cancer cells","volume":"21","author":"J\u0119drzejewski","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.jep.2022.115790_bib23","first-page":"1675","article-title":"Suppression of growth and invasive behavior of human prostate cancer cells by ProstaCaid\u2122: mechanism of activity","volume":"38","author":"Jiang","year":"2011","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.jep.2022.115790_bib24","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/1471-2407-8-78","article-title":"The immunomodulator PSK induces in vitro cytotoxic activity in tumour cell lines via arrest of cell cycle and induction of apoptosis","volume":"8","author":"Jim\u00e9nez-Medina","year":"2008","journal-title":"BMC Cancer"},{"issue":"10","key":"10.1016\/j.jep.2022.115790_bib25","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1038\/nri1703","article-title":"NF-kappaB: linking inflammation and immunity to cancer development and progression","volume":"5","author":"Karin","year":"2005","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jep.2022.115790_bib26","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1093\/oxfordjournals.jncimonographs.a003437","article-title":"Infection and mucosal injury in cancer treatment","volume":"29","author":"Khan","year":"2001","journal-title":"J. Natl. Cancer Inst. Monogr."},{"issue":"1","key":"10.1016\/j.jep.2022.115790_bib27","first-page":"4","article-title":"The use of mushroom glucans and proteoglycans in cancer treatment","volume":"5","author":"Kidd","year":"2000","journal-title":"Alternative Med. Rev."},{"issue":"11","key":"10.1016\/j.jep.2022.115790_bib28","doi-asserted-by":"crossref","first-page":"4300","DOI":"10.3390\/molecules14114300","article-title":"Silibinin suppresses TNF-alpha-induced MMP-9 expression in gastric cancer cells through inhibition of the MAPK pathway","volume":"14","author":"Kim","year":"2009","journal-title":"Molecules"},{"issue":"4","key":"10.1016\/j.jep.2022.115790_bib29","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.cell.2016.11.037","article-title":"Emerging biological principles of metastasis","volume":"168","author":"Lambert","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.jep.2022.115790_bib30","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/149185","article-title":"Chronic inflammation and cytokines in the tumor microenvironment","author":"Landskron","year":"2014","journal-title":"J. Immunol. Res."},{"issue":"16","key":"10.1016\/j.jep.2022.115790_bib31","doi-asserted-by":"crossref","first-page":"10147","DOI":"10.1128\/JVI.79.16.10147-10154.2005","article-title":"p38 mitogen-activated protein kinase-dependent hyperinduction of tumor necrosis factor alpha expression in response to avian influenza virus H5N1","volume":"79","author":"Lee","year":"2005","journal-title":"J. Virol."},{"issue":"3","key":"10.1016\/j.jep.2022.115790_bib32","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1007\/s12250-020-00320-4","article-title":"Tumor necrosis factor \u03b1 reduces SNAP29 dependent autolysosome formation to increase prion protein level and promote tumor cell migration","volume":"36","author":"Li","year":"2021","journal-title":"Virol. Sin."},{"issue":"14","key":"10.1016\/j.jep.2022.115790_bib33","doi-asserted-by":"crossref","first-page":"3055","DOI":"10.1016\/j.febslet.2005.04.060","article-title":"Mechanisms for HIV Tat upregulation of IL-10 and other cytokine expression: kinase signaling and PKR-mediated immune response","volume":"579","author":"Li","year":"2005","journal-title":"FEBS Lett."},{"issue":"2","key":"10.1016\/j.jep.2022.115790_bib34","doi-asserted-by":"crossref","first-page":"133","DOI":"10.4048\/jbc.2013.16.2.133","article-title":"The effect of curcumin on breast cancer cells","volume":"16","author":"Liu","year":"2013","journal-title":"J. Breast Cancer"},{"key":"10.1016\/j.jep.2022.115790_bib35","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1016\/j.phymed.2014.04.020","article-title":"In vivo and in vitro anti-tumor and anti-metastasis effects of Coriolus versicolor aqueous extract on mouse mammary 4T1 carcinoma","volume":"21","author":"Luo","year":"2014","journal-title":"Phytomedine"},{"issue":"6","key":"10.1016\/j.jep.2022.115790_bib36","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21061913","article-title":"The p38 pathway: from biology to cancer therapy","volume":"21","author":"Mart\u00ednez-Lim\u00f3n","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.jep.2022.115790_bib37","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1093\/carcin\/23.5.795","article-title":"Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the alpha,beta-unsaturated carbonyl group is a prerequisite","volume":"23","author":"Murakami","year":"2002","journal-title":"Carcinogenesis"},{"issue":"1","key":"10.1016\/j.jep.2022.115790_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0306-3623(97)00076-1","article-title":"A review of research on the protein-bound polysaccharide (polysaccharopeptide, PSP) from the mushroom Coriolus versicolor (Basidiomycetes: polyporaceae)","volume":"30","author":"Ng","year":"1998","journal-title":"Gen. Pharmacol."},{"issue":"1","key":"10.1016\/j.jep.2022.115790_bib39","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.immuni.2014.06.010","article-title":"Tumor-associated macrophages: from mechanisms to therapy","volume":"41","author":"Noy","year":"2014","journal-title":"Immunity"},{"issue":"6","key":"10.1016\/j.jep.2022.115790_bib40","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s00262-006-0248-1","article-title":"Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curative resections of gastric cancer","volume":"56","author":"Oba","year":"2007","journal-title":"Cancer Immunol. Immunother."},{"issue":"5","key":"10.1016\/j.jep.2022.115790_bib41","doi-asserted-by":"crossref","first-page":"178","DOI":"10.3892\/ol.2020.12039","article-title":"Antitumor effects of ribavirin in combination with TMZ and IFN-\u03b2 in malignant glioma cells","volume":"20","author":"Ochiai","year":"2020","journal-title":"Oncol. Lett."},{"issue":"6","key":"10.1016\/j.jep.2022.115790_bib42","doi-asserted-by":"crossref","first-page":"3581","DOI":"10.1016\/S0021-9258(19)50563-4","article-title":"Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9","volume":"267","author":"Ogata","year":"1992","journal-title":"J. Biol. Chem."},{"issue":"1\u20132","key":"10.1016\/j.jep.2022.115790_bib43","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s11010-013-1752-1","article-title":"Curcumin enhances TRAIL-induced apoptosis of breast cancer cells by regulating apoptosis-related proteins","volume":"383","author":"Park","year":"2013","journal-title":"Mol. Cell. Biochem."},{"issue":"1","key":"10.1016\/j.jep.2022.115790_bib44","doi-asserted-by":"crossref","first-page":"45","DOI":"10.12793\/jkscpt.1993.1.1.45","article-title":"Efficacy and safety of Coriolus versicolor polysaccharide (Licovek) in the treatment of chronic type B hepatitis","volume":"1","author":"Park","year":"1993","journal-title":"J. Korean Soc. Clin. Pharmacol. Ther."},{"issue":"3","key":"10.1016\/j.jep.2022.115790_bib45","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/nrc.2016.14","article-title":"Antitumour actions of interferons: implications for cancer therapy","volume":"16","author":"Parker","year":"2016","journal-title":"Nat. Rev. Cancer"},{"issue":"1","key":"10.1016\/j.jep.2022.115790_bib46","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.cell.2010.03.014","article-title":"Macrophage diversity enhances tumor progression and metastasis","volume":"141","author":"Qian","year":"2010","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.jep.2022.115790_bib47","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1142\/S0192415X97000068","article-title":"Polysaccharide peptide (PSP) restores immunosuppression induced by cyclophosphamide in rats","volume":"25","author":"Qian","year":"1997","journal-title":"Am. J. Chin. Med."},{"issue":"37","key":"10.1016\/j.jep.2022.115790_bib48","doi-asserted-by":"crossref","first-page":"4860","DOI":"10.1016\/j.vaccine.2008.06.098","article-title":"Evaluation of widely consumed botanicals as immunological adjuvants","volume":"26","author":"Ragupathi","year":"2008","journal-title":"Vaccine"},{"key":"10.1016\/j.jep.2022.115790_bib49","doi-asserted-by":"crossref","first-page":"231","DOI":"10.7150\/ijms.28811","article-title":"In vitro anti-proliferative and anti-invasive effect of polysaccharide-rich extracts from Trametes versicolor and Grifola frondosa in colon cancer cells","volume":"16","author":"Roca-Lema","year":"2019","journal-title":"Int. J. Med. Sci."},{"issue":"4","key":"10.1016\/j.jep.2022.115790_bib50","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1007\/s00262-005-0054-1","article-title":"Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curatively resected colorectal cancer: a meta-analysis of centrally randomized controlled clinical trials","volume":"55","author":"Sakamoto","year":"2006","journal-title":"Cancer Immunol. Immunother."},{"key":"10.1016\/j.jep.2022.115790_bib51","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.3389\/fimmu.2017.01087","article-title":"Immunomodulatory properties of Coriolus versicolor: the role of polysaccharopeptide","volume":"8","author":"Saleh","year":"2017","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.jep.2022.115790_bib52","doi-asserted-by":"crossref","first-page":"407","DOI":"10.3892\/ijo.2018.4661","article-title":"From chemotherapy to biological therapy: a review of novel concepts to reduce the side effects of systemic cancer treatment (Review)","volume":"54","author":"Schirrmacher","year":"2019","journal-title":"Int. J. Oncol."},{"issue":"4","key":"10.1016\/j.jep.2022.115790_bib53","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.12441","article-title":"Anti-cancer therapy with TNF\u03b1 and IFN\u03b3: a comprehensive review","volume":"51","author":"Shen","year":"2018","journal-title":"Cell Prolif"},{"key":"10.1016\/j.jep.2022.115790_bib54","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1186\/1748-717X-8-101","article-title":"Concurrent bevacizumab and temozolomide alter the patterns of failure in radiation treatment of glioblastoma multiforme","volume":"8","author":"Shields","year":"2013","journal-title":"Radiat. Oncol."},{"issue":"3","key":"10.1016\/j.jep.2022.115790_bib55","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1007\/s12032-013-0638-0","article-title":"Vandetanib combined with a p38 MAPK inhibitor synergistically reduces glioblastoma cell survival","volume":"30","author":"Sooman","year":"2013","journal-title":"Med. Oncol."},{"issue":"3","key":"10.1016\/j.jep.2022.115790_bib56","first-page":"122","article-title":"Trametes versicolor mushroom immune therapy in breast cancer","volume":"6","author":"Standish","year":"2008","journal-title":"J. Soc. Integr. Oncol."},{"issue":"2","key":"10.1016\/j.jep.2022.115790_bib57","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.cell.2011.09.024","article-title":"Tumor metastasis: molecular insights and evolving paradigms","volume":"147","author":"Valastyan","year":"2011","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.jep.2022.115790_bib58","doi-asserted-by":"crossref","first-page":"685","DOI":"10.3892\/or.2020.7620","article-title":"UBR5 regulates proliferation and radiosensitivity in human laryngeal carcinoma via the p38\/MAPK signaling pathway","volume":"44","author":"Wang","year":"2020","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.jep.2022.115790_bib59","series-title":"World Cancer Report: Cancer Research for Cancer Prevention","author":"Wild","year":"2020"},{"issue":"6","key":"10.1016\/j.jep.2022.115790_bib60","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1054\/bjoc.1999.1053","article-title":"Interferon-gamma in the first-line therapy of ovarian cancer: a randomized phase III trial","volume":"82","author":"Windbichler","year":"2000","journal-title":"Br. J. Cancer"},{"issue":"6","key":"10.1016\/j.jep.2022.115790_bib61","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1158\/1535-7163.MCT-17-0646","article-title":"Matrix metalloproteinase inhibitors in cancer therapy: turning past failures into future successes","volume":"17","author":"Winer","year":"2018","journal-title":"Mol. Cancer Therapeut."},{"issue":"4","key":"10.1016\/j.jep.2022.115790_bib62","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s13402-016-0280-x","article-title":"TNF-\u03b1 promotes breast cancer cell migration and enhances the concentration of membrane-associated proteases in lipid rafts","volume":"39","author":"Wolczyk","year":"2016","journal-title":"Cell. Oncol."},{"issue":"1","key":"10.1016\/j.jep.2022.115790_bib63","doi-asserted-by":"crossref","DOI":"10.1016\/j.yexcr.2020.112110","article-title":"UCP2 silencing in glioblastoma reduces cell proliferation and invasiveness by inhibiting p38 MAPK pathway","volume":"394","author":"Wu","year":"2020","journal-title":"Exp. Cell Res."},{"issue":"5","key":"10.1016\/j.jep.2022.115790_bib64","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1002\/mc.21875","article-title":"Curcumin enhances the anticancer effects of trichostatin a in breast cancer cells","volume":"52","author":"Yan","year":"2013","journal-title":"Mol. Carcinog."},{"issue":"21","key":"10.1016\/j.jep.2022.115790_bib65","doi-asserted-by":"crossref","first-page":"6707","DOI":"10.1021\/jm9006164","article-title":"Identification of the bioactive constituent and its mechanisms of action in mediating the anti-inflammatory effects of black cohosh and related Cimicifuga species on human primary blood macrophages","volume":"52","author":"Yang","year":"2009","journal-title":"J. Med. Chem."},{"issue":"3 Pt 1","key":"10.1016\/j.jep.2022.115790_bib66","first-page":"520","article-title":"[Combination therapy with IFN-beta, ACNU and radiation (IAR) in malignant brain tumors]","volume":"13","author":"Yoshida","year":"1986","journal-title":"Gan To Kagaku Ryoho"},{"key":"10.1016\/j.jep.2022.115790_bib67","article-title":"Zerumbone, a southeast asian ginger sesquiterpene, induced apoptosis of pancreatic carcinoma cells through p53 signaling pathway, evid. Based complement","author":"Zhang","year":"2012","journal-title":"Alternat. Med."},{"key":"10.1016\/j.jep.2022.115790_bib68","first-page":"35","article-title":"Clinical observation on Oriental Coriolus versicolor in the treatment of viral hepatitis","volume":"9","author":"Zhang","year":"1994","journal-title":"Shanghai J. Tradit. Chin. Med."},{"issue":"2","key":"10.1016\/j.jep.2022.115790_bib69","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/path.5362","article-title":"p38-regulated FOXC1 stability is required for colorectal cancer metastasis","volume":"250","author":"Zhang","year":"2020","journal-title":"J. Pathol."},{"issue":"3","key":"10.1016\/j.jep.2022.115790_bib70","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1007\/s11418-015-0892-x","article-title":"9-Oxo-(10E,12E)-octadecadienoic acid, a cytotoxic fatty acid ketodiene isolated from eggplant calyx, induces apoptosis in human ovarian cancer (HRA) cells","volume":"69","author":"Zhao","year":"2015","journal-title":"J. Nat. Med."},{"issue":"3","key":"10.1016\/j.jep.2022.115790_bib71","first-page":"3820","article-title":"TNF-\u03b1 promotes colon cancer cell migration and invasion by upregulating TROP-2","volume":"15","author":"Zhao","year":"2018","journal-title":"Oncol. Lett."},{"issue":"9","key":"10.1016\/j.jep.2022.115790_bib72","doi-asserted-by":"crossref","first-page":"5513","DOI":"10.7314\/APJCP.2013.14.9.5513","article-title":"Anti-proliferation effects of interferon-gamma on gastric cancer cells","volume":"14","author":"Zhao","year":"2013","journal-title":"Asian Pac. J. Cancer Prev. APJCP"},{"key":"10.1016\/j.jep.2022.115790_bib73","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.canlet.2016.10.008","article-title":"Targeting p38 MAP kinase signaling in cancer through post-translational modifications","volume":"384","author":"Zou","year":"2017","journal-title":"Cancer Lett."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874122008297?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874122008297?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:36:26Z","timestamp":1759944986000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874122008297"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":73,"alternative-id":["S0378874122008297"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2022.115790","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Coriolus versicolor and its bioactive molecule are potential immunomodulators against cancer cell metastasis via inactivation of MAPK pathway","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2022.115790","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"115790"}}