{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T01:55:54Z","timestamp":1767146154519,"version":"build-2238731810"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.jep.2023.116189","type":"journal-article","created":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T11:41:49Z","timestamp":1676288509000},"page":"116189","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Deciphering antidiarrheal effects of Meda pata (Litsea glutinosa (Lour.) C.B.Rob.) leaf extract in chemical-induced models of albino rats"],"prefix":"10.1016","volume":"308","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5585-7480","authenticated-orcid":false,"given":"Nazifa","family":"Anjum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md. Saddam","family":"Hossain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4902-8923","authenticated-orcid":false,"given":"Md. Atiar","family":"Rahman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5117-6829","authenticated-orcid":false,"given":"Md. Khalid Juhani","family":"Rafi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah","family":"Al Noman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirola","family":"Afroze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srabonti","family":"Saha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walla","family":"Alelwani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jitbanjong","family":"Tangpong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2023.116189_bib1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.sajb.2019.09.007","article-title":"Padina tenuis (marine alga) attenuates oxidative stress and streptozotocin-induced type 2 diabetic indices in Wistar albino rats","volume":"128","author":"Al-Araby","year":"2019","journal-title":"South Afr. J. Bot."},{"key":"10.1016\/j.jep.2023.116189_bib2","doi-asserted-by":"crossref","first-page":"258","DOI":"10.22159\/ijpps.2016v8i12.13577","article-title":"Antibacterial and antioxidant activities of stem bark essential oil constituents of Litsea glutinosa C. B. ROB","volume":"8","author":"Arunodaya","year":"2016","journal-title":"Int. J. Pharm. Pharmaceut. Sci."},{"key":"10.1016\/j.jep.2023.116189_bib3","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.3390\/jcm9061901","article-title":"Magnesium, calcium, potassium, sodium, phosphorus, selenium, zinc, and chromium levels in alcohol use disorder: a review","volume":"9","author":"Baj","year":"2020","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.jep.2023.116189_bib4","doi-asserted-by":"crossref","first-page":"G215","DOI":"10.1152\/ajpgi.00072.2010","article-title":"Comparison of selective M3 and nonselective muscarinic receptor antagonists on gastrointestinal transit and bowel habits in humans","volume":"299","author":"Bharucha","year":"2010","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.jep.2023.116189_bib5","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1016\/S0140-6736(10)60549-1","article-title":"Global, regional, and national causes of child mortality in 2008: a systematic analysis","volume":"375","author":"Black","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.jep.2023.116189_bib6","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/nature17042","article-title":"Antibacterial drug discovery in the resistance era","volume":"529","author":"Brown","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.jep.2023.116189_bib7","series-title":"Handbook on Laboratory Mice and Rats","first-page":"157","author":"Chatterjee","year":"1993"},{"key":"10.1016\/j.jep.2023.116189_bib8","doi-asserted-by":"crossref","first-page":"73","DOI":"10.7324\/JAPS.2015.501112","article-title":"In silico analysis of indole-3-carbinol and its metabolite dim as egfr tyrosine kinase inhibitors in platinum resistant ovarian cancer Vis a Vis adme\/T property analysis","volume":"5","author":"Dash","year":"2015","journal-title":"J. Appl. Pharmaceut. Sci."},{"key":"10.1016\/j.jep.2023.116189_bib9","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1111\/j.1476-5381.1981.tb10454.x","article-title":"Inhibition of arachidonic acid release, mechanism by which glucocorticoids inhibit endotoxin-induced diarrhoea","volume":"73","author":"Doherty","year":"1981","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.jep.2023.116189_bib10","series-title":"Biotic vs. Abiotic\u2014Distinguishing Disease Problems from Environmental Stresses","author":"Flynn","year":"2003"},{"key":"10.1016\/j.jep.2023.116189_bib11","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1021\/jm0306430","article-title":"Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy","volume":"47","author":"Friesner","year":"2004","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jep.2023.116189_bib12","series-title":"Medicinal Plants of Bangladesh: Chemical Constituents and Uses","author":"Ghani","year":"1998"},{"key":"10.1016\/j.jep.2023.116189_bib13","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/B978-0-12-819978-7.00008-7","article-title":"Endophytic microbes and their role to overcome abiotic stress in crop plants","author":"Gorai","year":"2020","journal-title":"Microbial. Service Restorate. Ecol."},{"key":"10.1016\/j.jep.2023.116189_bib14","doi-asserted-by":"crossref","first-page":"165","DOI":"10.3329\/dujbs.v23i2.20096","article-title":"Propagation, antibacterial activity and phytochemical profiles of Litsea glutinosa (Lour.) C. B. Robinson","volume":"23","author":"Haque","year":"2014","journal-title":"Dhaka Univ. J. Biol. Sci."},{"key":"10.1016\/j.jep.2023.116189_bib15","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/B978-0-12-386960-9.00004-6","article-title":"Retinoic acid, immunity, and inflammation","volume":"86","author":"Kim","year":"2011","journal-title":"Vitam. Horm."},{"key":"10.1016\/j.jep.2023.116189_bib16","doi-asserted-by":"crossref","first-page":"21","DOI":"10.15835\/nsb10110180","article-title":"Litsea glutinosa (lauraceae): evaluation of its foliar phytochemical constituents for antimicrobial activity","volume":"10","author":"Lagudu","year":"2018","journal-title":"Not. Sci. Biol."},{"key":"10.1016\/j.jep.2023.116189_bib17","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0169-409X(00)00129-0","article-title":"Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings","volume":"46","author":"Lipinski","year":"2001","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jep.2023.116189_bib18","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jep.2007.10.037","article-title":"Anti-diarrhoeal activity of the aqueous extract of Mezoneuron benthamianum Baill (Caesalpiniaceae)","volume":"116","author":"Mbagwu","year":"2008","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2023.116189_bib19","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/ncpgasthep1264","article-title":"Mechanisms of infectious diarrhea","volume":"5","author":"Navaneethan","year":"2008","journal-title":"Nat. Clin. Pract. Gastroenterol. Hepatol."},{"key":"10.1016\/j.jep.2023.116189_bib20","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1007\/s11894-010-0129-9","article-title":"Enteric nervous system in the small intestine: pathophysiology and clinical implications","volume":"12","author":"Nezami","year":"2010","journal-title":"Curr. Gastroenterol. Rep."},{"key":"10.1016\/j.jep.2023.116189_bib21","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1002\/ptr.1907","article-title":"Phytochemicals from traditional medicinal plants used in the treatment of diarrhoea: modes of action and effects on intestinal function","volume":"20","author":"Palombo","year":"2006","journal-title":"Phytother Res."},{"key":"10.1016\/j.jep.2023.116189_bib22","first-page":"74","article-title":"Toxicological screening","volume":"2","author":"Parasuraman","year":"2012","journal-title":"J. Pharmacol. Pharmacother."},{"issue":"4","key":"10.1016\/j.jep.2023.116189_bib23","first-page":"550","article-title":"In silico screening of antibacterial compounds from herbal sources against Vibrio cholerae","volume":"11","author":"Perveen","year":"2015","journal-title":"Phcog. Mag."},{"key":"10.1016\/j.jep.2023.116189_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1472-6807-8-38","article-title":"Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB\/DNA interactions and inhibitory effects on IL-8 gene expression","volume":"8","author":"Piccagli","year":"2008","journal-title":"BMC Struct. Biol."},{"key":"10.1016\/j.jep.2023.116189_bib25","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1469-0691.2004.01044.x","article-title":"C-reactive protein as a marker of infection in critically ill patients","volume":"11","author":"P\u00f3voa","year":"2005","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.jep.2023.116189_bib26","first-page":"182","article-title":"Antinociceptive property of leaves extract of Litsea glutinosa","volume":"6","author":"Pradeepa","year":"2013","journal-title":"Asian J. Pharmaceut. Clin. Res."},{"key":"10.1016\/j.jep.2023.116189_bib27","first-page":"293","article-title":"Comparison of antidiarrhoeal activity of some drugs in experimental diarrhoea","volume":"14","author":"Radha","year":"1982","journal-title":"Indian J. Pharmacol."},{"key":"10.1016\/j.jep.2023.116189_bib28","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/S2221-1691(13)60129-X","article-title":"Studies on the antidiarrheal properties of leaf extract of Desmodium puchellum","volume":"3","author":"Rahman","year":"2013","journal-title":"Asian Pac. J. Trop. Biomed."},{"key":"10.1016\/j.jep.2023.116189_bib29","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/j.biopha.2017.11.147","article-title":"Evidence based traditional anti-diarrheal medicinal plants and their phytocompounds","volume":"96","author":"Rawat","year":"2017","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2023.116189_bib30","doi-asserted-by":"crossref","first-page":"3685","DOI":"10.1021\/jm100057h","article-title":"Development of a new generation of 4-aminoquinoline antimalarial compounds using predictive pharmacokinetic and toxicology models","volume":"53","author":"Ray","year":"2010","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jep.2023.116189_bib31","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.jep.2013.03.083","article-title":"Anti-diarrhoeal activity of aqueous extract of Ocimum kilimandscharicum","volume":"148","author":"Sarin","year":"2013","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2023.116189_bib32","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/cid\/cix669","article-title":"Infectious Diseases Society of America clinical practice guidelines for the diagnosis and management of infectious diarrhea","volume":"65","author":"Shane","year":"2017","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.jep.2023.116189_bib33","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0378-8741(00)00379-2","article-title":"Study of antidiarrhoeal activity of four medicinal plants in castor-oil induced diarrhoea","volume":"76","author":"Shoba","year":"2001","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2023.116189_bib34","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.foodchem.2015.11.127","article-title":"Enhancing phytochemical levels, enzymatic and antioxidant activity of spinach leaves by chitosan treatment and an insight into the metabolic pathway using DART-MS technique","volume":"199","author":"Singh","year":"2016","journal-title":"Food Chem."},{"key":"10.1016\/j.jep.2023.116189_bib35","doi-asserted-by":"crossref","first-page":"2411","DOI":"10.1021\/acs.jcim.5b00538","article-title":"Accurate binding free energy predictions in fragment optimization","volume":"55","author":"Steinbrecher","year":"2015","journal-title":"J. Chem. Inf. Model."},{"key":"10.1016\/j.jep.2023.116189_bib36","first-page":"880","article-title":"Cytotoxicity and oral acute toxicity studies of Litsea glutinosa C. B (ROB) stem bark ethanol extract","volume":"9","author":"Sumithregowda","year":"2017","journal-title":"Pharmacogenomics J."},{"key":"10.1016\/j.jep.2023.116189_bib37","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1056\/NEJMcp031534","article-title":"Acute infectious diarrhea","volume":"350","author":"Thielman","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jep.2023.116189_bib38","first-page":"14","article-title":"Antidiarrheal activity of aqueous leaf extract of Ceratotheca sesamoides in rats","volume":"7","author":"Toyin","year":"2012","journal-title":"Bangladesh J. Pharmacol."},{"key":"10.1016\/j.jep.2023.116189_bib39","doi-asserted-by":"crossref","first-page":"9179","DOI":"10.1073\/pnas.1201627109","article-title":"Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors","volume":"109","author":"Tunaru","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jep.2023.116189_bib40","first-page":"1","article-title":"Antidiarrhoeal and antimicrobial activity of Calpurnia aurea leaf extract","volume":"13","author":"Umer","year":"2013","journal-title":"BMC Compl. Alternative Med."},{"key":"10.1016\/j.jep.2023.116189_bib41","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.paed.2012.05.006","article-title":"Pathophysiology of diarrhoea","volume":"22","author":"Whyte","year":"2012","journal-title":"Paediatr. Child Health"},{"key":"10.1016\/j.jep.2023.116189_bib42","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1078\/0944-7113-00084","article-title":"Acute and chronic toxicity of Nigella sativa fixed oil","volume":"9","author":"Zaoui","year":"2002","journal-title":"Phytomedicine"}],"updated-by":[{"DOI":"10.1016\/j.jep.2023.116495","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2023,7,15]],"date-time":"2023-07-15T00:00:00Z","timestamp":1689379200000}}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874123000570?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874123000570?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,3,11]],"date-time":"2023-03-11T04:57:19Z","timestamp":1678510639000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874123000570"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":42,"alternative-id":["S0378874123000570"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2023.116189","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Deciphering antidiarrheal effects of Meda pata (Litsea glutinosa (Lour.) C.B.Rob.) leaf extract in chemical-induced models of albino rats","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2023.116189","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"116189"}}