{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T23:44:04Z","timestamp":1777074244358,"version":"3.51.4"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T00:00:00Z","timestamp":1676332800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.jep.2023.116246","type":"journal-article","created":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T11:42:29Z","timestamp":1676288549000},"page":"116246","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Cymbaria daurica L.: A Mongolian herbal medicine for treating eczema via natural killer cell-mediated cytotoxicity pathway"],"prefix":"10.1016","volume":"308","author":[{"given":"Congying","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siqi","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenxin","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziyan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangxi","family":"Meng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xing","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Wen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Niu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunhong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minhui","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2023.116246_bib1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/jdv.16061","article-title":"Hand eczema: epidemiology, prognosis and prevention","volume":"1","author":"Agner","year":"2020","journal-title":"J. Eur. Acad. Dermatol. Venereol.: JEADV"},{"key":"10.1016\/j.jep.2023.116246_bib2","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.peptides.2015.04.012","article-title":"A short history, principles, and types of ELISA, and our laboratory experience with peptide\/protein analyses using ELISA","volume":"72","author":"Aydin","year":"2015","journal-title":"Peptides"},{"key":"10.1016\/j.jep.2023.116246_bib3","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.chmed.2022.06.001","article-title":"Traditional Mongolian medicine: past, present and future","volume":"14","author":"Bai","year":"2022","journal-title":"Chin. Herbal Med."},{"key":"10.1016\/j.jep.2023.116246_bib4","first-page":"377","article-title":"The isolation and structural elucidation of a new iridoid glycoside from Cymbaria dahurica L. Zeitschrift Fur Naturforschung, B","volume":"73","author":"Bai","year":"2018","journal-title":"J. Chem. Sci."},{"key":"10.1016\/j.jep.2023.116246_bib5","doi-asserted-by":"crossref","first-page":"66","DOI":"10.7861\/clinmedicine.16-1-66","article-title":"Atopic eczema","volume":"16","author":"Brown","year":"2016","journal-title":"Clin. Med."},{"key":"10.1016\/j.jep.2023.116246_bib6","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1038\/jid.2011.393","article-title":"One remarkable molecule: filaggrin","volume":"132","author":"Brown","year":"2012","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jep.2023.116246_bib7","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.psyneuen.2005.10.006","article-title":"Endocrine stress responses in TH1-mediated chronic inflammatory skin disease (psoriasis vulgaris)\u2014do they parallel stress-induced endocrine changes in TH2-mediated inflammatory dermatoses (atopic dermatitis)?","volume":"31","author":"Buske-Kirschbaum","year":"2006","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jep.2023.116246_bib8","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1007\/s12016-007-0033-8","article-title":"Treatment of eczema","volume":"33","author":"Chang","year":"2007","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"10.1016\/j.jep.2023.116246_bib9","article-title":"The expression of BAFF, APRIL and TWEAK is altered in eczema skin but not in the circulation of atopic and seborrheic eczema patients","volume":"6","author":"Chen","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2023.116246_bib10","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1038\/sj.ejhg.5201541","article-title":"Family based association analysis of the IL2 and IL15 genes in allergic disorders","volume":"14","author":"Christensen","year":"2006","journal-title":"Eur. J. Hum. Genet.: EJHG (Eur. J. Hum. Genet.)"},{"key":"10.1016\/j.jep.2023.116246_bib11","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1056\/NEJMcp1104084","article-title":"Hand eczema","volume":"367","author":"Coenraads","year":"2012","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jep.2023.116246_bib12","doi-asserted-by":"crossref","first-page":"2712","DOI":"10.1002\/art.23757","article-title":"Vav\/Phospholipase Cgamma2-mediated control of a neutrophil-dependent murine model of rheumatoid arthritis","volume":"58","author":"Cremasco","year":"2008","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jep.2023.116246_bib13","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0031-9422(01)00488-5","article-title":"Non-glycosidic iridoids from Cymbaria mongolica","volume":"59","author":"Dai","year":"2002","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jep.2023.116246_bib14","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/BOR.0b013e32832a0760","article-title":"Anticytokine therapy impacting on B cells in autoimmune diseases","volume":"21","author":"Daridon","year":"2009","journal-title":"Curr. Opin. Rheumatol."},{"key":"10.1016\/j.jep.2023.116246_bib15","first-page":"3649","article-title":"Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1","volume":"8","author":"Dong","year":"2015","journal-title":"OncoTargets Ther."},{"key":"10.1016\/j.jep.2023.116246_bib17","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.jaad.2013.10.010","article-title":"Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis","volume":"70","author":"Eichenfield","year":"2014","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.jep.2023.116246_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114474","article-title":"Anti-atopic effect of Viola yedoensis ethanol extract against 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin dysfunction","volume":"280","author":"Fan","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2023.116246_bib19","first-page":"194","article-title":"Research progress in the treatment of chronic eczema with Mongolian medicine Xinba","volume":"15","author":"Ge","year":"2019","journal-title":"Asia-Pacific Traditional Medicine"},{"key":"10.1016\/j.jep.2023.116246_bib20","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/exd.14270","article-title":"Mouse models of atopic dermatitis: a critical reappraisal","volume":"30","author":"Gilhar","year":"2021","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.jep.2023.116246_bib21","series-title":"Screening of Antidiabetic Active Components of Cymbaria daurica and Exploring of Their Mechanism. Baotou Medical College","first-page":"1","author":"Gong","year":"2020"},{"key":"10.1016\/j.jep.2023.116246_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphar.2020.00048","article-title":"Bioactivity, compounds isolated, chemical qualitative, and quantitative analysis of Cymbaria daurica extracts","volume":"11","author":"Gong","year":"2020","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2023.116246_bib23","first-page":"64","article-title":"Study on anti-inflammatory and analgesic effects of Mongolian medicine Cymbaria dahurica extract","volume":"28","author":"Guo","year":"2017","journal-title":"China Pharm."},{"key":"10.1016\/j.jep.2023.116246_bib24","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1038\/jid.2008.252","article-title":"Evolving concepts of pathogenesis in atopic dermatitis and other eczemas","volume":"129","author":"Hanifin","year":"2008","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jep.2023.116246_bib25","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1111\/j.1365-2133.1976.tb06118.x","article-title":"Histological aspects of DNCB sensitization and challenge tests","volume":"94","author":"Hartman","year":"1976","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.jep.2023.116246_bib27","first-page":"2878","article-title":"Solanum nigrum Linne improves DNCB induced atopic dermatitislike skin disease in BALB\/c mice","volume":"22","author":"Hong","year":"2020","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.jep.2023.116246_bib28","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.plefa.2006.02.007","article-title":"Evaluation and interference of serum and skin lesion levels of leukotrienes in patients with eczema","volume":"75","author":"Hua","year":"2006","journal-title":"Prostagl. Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.jep.2023.116246_bib29","series-title":"Technical Specifications for National General Survey of Traditional Chinese Medicine Resources","first-page":"119","author":"Huang","year":"2015"},{"key":"10.1016\/j.jep.2023.116246_bib32","doi-asserted-by":"crossref","first-page":"789","DOI":"10.3390\/pharmaceutics12090789","article-title":"Advanced characterization of imiquimod-induced psoriasis-like mouse model","volume":"12","author":"Jabeen","year":"2020","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.jep.2023.116246_bib33","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.4049\/jimmunol.1200551","article-title":"Deficiency in hematopoietic phosphatase ptpn6\/Shp1 hyperactivates the innate immune system and impairs control of bacterial infections in zebrafish embryos","volume":"190","author":"Kanwal","year":"2013","journal-title":"J. Immunol."},{"key":"10.1016\/j.jep.2023.116246_bib34","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1007\/s00403-011-1149-5","article-title":"Decisive role of tumor necrosis factor-\u03b1 for spongiosis formation in acute eczematous dermatitis","volume":"303","author":"Kerstan","year":"2011","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.jep.2023.116246_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114453","article-title":"Effects of chloroform fraction of Fritillariae Thunbergii Bulbus on atopic symptoms in a DNCB-induced atopic dermatitis-like skin lesion model and in vitro models","volume":"281","author":"Kim","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2023.116246_bib36","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1093\/biostatistics\/kxu057","article-title":"Informative prior distributions for ELISA analyses","volume":"16","author":"Klauenberg","year":"2015","journal-title":"Biostatistics"},{"key":"10.1016\/j.jep.2023.116246_bib37","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1084\/jem.172.6.1609","article-title":"Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light","volume":"172","author":"K\u00f6ck","year":"1990","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jep.2023.116246_bib38","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0140-6736(20)31286-1","article-title":"Atopic dermatitis","volume":"396","author":"Langan","year":"2020","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.jep.2023.116246_bib39","doi-asserted-by":"crossref","DOI":"10.1111\/dth.12840","article-title":"Current and emerging therapies for hand eczema","volume":"32","author":"Lee","year":"2019","journal-title":"Dermatol. Ther."},{"key":"10.1016\/j.jep.2023.116246_bib40","first-page":"709","article-title":"Expert consensus on the clinical application of antihistamines in the treatment of dermatitis and eczema dermatosis","volume":"19","author":"Li","year":"2021","journal-title":"Chin. J. General Pract."},{"key":"10.1016\/j.jep.2023.116246_bib41","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1684\/ejd.2013.2185","article-title":"Topical application of a Chinese medicine, Qingpeng ointment, ameliorates 2, 4-dinitrofluorobenzene-induced allergic contact dermatitis in BALB\/c mice","volume":"23","author":"Li","year":"2013","journal-title":"Eur. J. Dermatol."},{"key":"10.1016\/j.jep.2023.116246_bib42","first-page":"21","article-title":"Western medicine treatment of eczema","volume":"39","author":"Li","year":"2011","journal-title":"Chin. J. Clin."},{"key":"10.1016\/j.jep.2023.116246_bib43","first-page":"272","article-title":"Overview of modern research and development of Mongolian medicine","volume":"45","author":"Li","year":"2019","journal-title":"J. Southwest Minzu Univ."},{"key":"10.1016\/j.jep.2023.116246_bib44","first-page":"1","article-title":"Acteoside counteracts interleukin-1\u03b2-induced catabolic processes through the modulation of mitogen-activated protein kinases and the NF\u03baB cellular signaling pathway","author":"Lim","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.jep.2023.116246_bib45","doi-asserted-by":"crossref","first-page":"9859","DOI":"10.1073\/pnas.1805474115","article-title":"Raf kinase inhibitor protein negatively regulates Fc\u03b5RI-mediated mast cell activation and allergic response","volume":"115","author":"Lin","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.jep.2023.116246_bib46","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.chmed.2022.06.005","article-title":"Discussion on evolution of Mongolian medicinal material names and countermeasures for standardization","volume":"14","author":"Long","year":"2022","journal-title":"Chin. Herbal Med."},{"key":"10.1016\/j.jep.2023.116246_bib47","first-page":"53","article-title":"Coix lacryma-jobi, forsythia suspensa and vigna umbellata decoction for chronic eczema","volume":"6","author":"Lu","year":"1992","journal-title":"Beijing J. Trad. Chin. Med."},{"key":"10.1016\/j.jep.2023.116246_bib49","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2022.986943","article-title":"Portulaca oleracea L. extracts alleviate 2,4-dinitrochlorobenzene-induced atopic dermatitis in mice","volume":"9","author":"Lv","year":"2022","journal-title":"Front. Nutr."},{"key":"10.1016\/j.jep.2023.116246_bib51","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1080\/14789450.2017.1388167","article-title":"Protein purification and analysis: next generation Western blotting techniques","volume":"14","author":"Mishra","year":"2017","journal-title":"Expet Rev. Proteonomics"},{"key":"10.1016\/j.jep.2023.116246_bib52","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1002\/jcc.21256","article-title":"AutoDock4 and AutoDockTools4: automated docking with selective receptor flexibility","volume":"30","author":"Morris","year":"2009","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.jep.2023.116246_bib53","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/jid.2008.192","article-title":"B-cell-directed therapy for inflammatory skin diseases","volume":"129","author":"Nagel","year":"2009","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jep.2023.116246_bib54","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1080\/09546634.2016.1230173","article-title":"Eczema as an adverse effect of anti-TNF\u03b1 therapy in psoriasis and other Th1-mediated diseases: a review","volume":"28","author":"Nakamura","year":"2017","journal-title":"J. Dermatol. Treat."},{"key":"10.1016\/j.jep.2023.116246_bib55","first-page":"CD008426","article-title":"House dust mite reduction and avoidance measures for treating eczema","volume":"1","author":"Nankervis","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.jep.2023.116246_bib56","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1006\/scel.1993.1050","article-title":"Structure and function of SH2-domain containing tyrosine phosphatases","volume":"4","author":"Neel","year":"1993","journal-title":"Semin. Cell Biol."},{"key":"10.1016\/j.jep.2023.116246_bib58","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/cod.12691","article-title":"Azathioprine treatment and drug survival in patients with chronic hand eczema - results from daily practice","volume":"76","author":"Oosterhaven","year":"2017","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.jep.2023.116246_bib59","first-page":"1377","article-title":"Research status of traditional Chinese medicine in the treatment of eczema","volume":"34","author":"Peng","year":"2022","journal-title":"Clin. J. Trad. Chin. Med."},{"key":"10.1016\/j.jep.2023.116246_bib60","first-page":"521","article-title":"Tips and tricks for controlling eczema","volume":"39","author":"Raveendran","year":"2019","journal-title":"Immunol. Allergy Clin."},{"key":"10.1016\/j.jep.2023.116246_bib61","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1038\/nprot.2008.73","article-title":"Analyzing real-time PCR data by the comparative C(T) method","volume":"3","author":"Schmittgen","year":"2008","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.jep.2023.116246_bib62","first-page":"22","article-title":"Antimicrobial activities of the extracts from Cymbaria daurica L","volume":"26","author":"Shi","year":"2020","journal-title":"J. Med. Pharm. Chin. Minor."},{"key":"10.1016\/j.jep.2023.116246_bib63","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jdermsci.2004.02.013","article-title":"Animal models for atopic dermatitis: are they relevant to human disease?","volume":"36","author":"Shiohara","year":"2004","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.jep.2023.116246_bib64","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1002\/msj.20289","article-title":"Eczema","volume":"78","author":"Sohn","year":"2011","journal-title":"Mt. Sinai J. Med."},{"key":"10.1016\/j.jep.2023.116246_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114571","article-title":"Deciphering the mechanism of Fang-Ji-Di-Huang-Decoction in ameliorating psoriasis-like skin inflammation via the inhibition of IL-23\/Th17 cell axis","volume":"281","author":"Song","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2023.116246_bib66","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.chmed.2022.06.002","article-title":"Connotation and scientific research points of processing of Mongolian medicinal materials","volume":"14","author":"Song","year":"2022","journal-title":"Chin. Herbal Med."},{"key":"10.1016\/j.jep.2023.116246_bib68","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/361590","article-title":"The design of a quantitative western blot experiment","volume":"2014","author":"Taylor","year":"2014","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.jep.2023.116246_bib69","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1124\/jpet.104.074815","article-title":"Selective inhibition of inflammatory gene expression in activated T lymphocytes: a mechanism of immune suppression by thiopurines","volume":"312","author":"Thomas","year":"2005","journal-title":"J. Pharmacol. Exp. Therapeut."},{"key":"10.1016\/j.jep.2023.116246_bib70","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1600-0536.2008.01346.x","article-title":"Hand eczema: causes, course, and prognosis II","volume":"58","author":"Veien","year":"2008","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.jep.2023.116246_bib71","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/ced.14902","article-title":"Eczema has different effects on the psychological state of patients depending on the site affected","volume":"47","author":"Wang","year":"2022","journal-title":"Clin. Exp. Dermatol."},{"key":"10.1016\/j.jep.2023.116246_bib72","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1142\/S0192415X17500094","article-title":"Review and reflections on research of Mongolian medicine","volume":"14","author":"Wang","year":"2017","journal-title":"China Medical Herald"},{"key":"10.1016\/j.jep.2023.116246_bib73","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1111\/jdv.13599","article-title":"ETFAD\/EADV eczema task force 2015 position paper on diagnosis and treatment of atopic dermatitis in adult and paediatric patients","volume":"30","author":"Wollenberg","year":"2016","journal-title":"J. Eur. Acad. Dermatol."},{"key":"10.1016\/j.jep.2023.116246_bib74","first-page":"5459","article-title":"MA Da-zheng\u2019s experience of treatment on gynecological miscellaneous diseases by using Mahuang Lianyao Chixiaodou Decoction","volume":"33","author":"Xu","year":"2018","journal-title":"China J. Trad. Chin. Med. Pharm."},{"key":"10.1016\/j.jep.2023.116246_bib75","first-page":"1","article-title":"Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome","volume":"6","author":"Yang","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jep.2023.116246_bib76","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.lfs.2021.119237","article-title":"Echinacoside improves diabetic liver injury by regulating the AMPK\/SIRT1 signaling pathway in db\/db mice","volume":"271","author":"Yang","year":"2021","journal-title":"Life Sci."},{"key":"10.1016\/j.jep.2023.116246_bib77","first-page":"5961","article-title":"Expert Consensus on clinical application of Fufang Jingjie for fumigation and washing","volume":"47","author":"Yu","year":"2022","journal-title":"China J. Chin. Mater. Med."},{"key":"10.1016\/j.jep.2023.116246_bib78","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1038\/ni.2064","article-title":"The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors","volume":"12","author":"Yuk","year":"2011","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.jep.2023.116246_bib79","first-page":"71","article-title":"Side effects of topical corticosteroids and suggestions for prevention and treatment","volume":"10","author":"Zhang","year":"1981","journal-title":"People's Mil. Surg."},{"key":"10.1016\/j.jep.2023.116246_bib81","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.chmed.2022.07.001","article-title":"Assessment of pulmonary infectious disease treatment with Mongolian medicine formulae based on data mining, network pharmacology and molecular docking","volume":"4","author":"Zhou","year":"2022","journal-title":"Chinese Herbal Med."},{"key":"10.1016\/j.jep.2023.116246_bib82","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fgene.2021.750681","article-title":"Study on the mechanism of baimai ointment in the treatment of osteoarthritis based on network pharmacology and molecular docking with experimental verification","volume":"12","author":"Zhu","year":"2021","journal-title":"Front. Genet."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874123001149?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874123001149?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:34:33Z","timestamp":1759944873000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874123001149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":73,"alternative-id":["S0378874123001149"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2023.116246","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cymbaria daurica L.: A Mongolian herbal medicine for treating eczema via natural killer cell-mediated cytotoxicity pathway","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2023.116246","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"116246"}}