{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T15:26:30Z","timestamp":1785770790567,"version":"3.56.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.jep.2023.116644","type":"journal-article","created":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T00:11:43Z","timestamp":1684195903000},"page":"116644","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Zhuidu Formula suppresses the migratory and invasive properties of triple-negative breast cancer cells via dual signaling pathways of RhoA\/ROCK and CDC42\/MRCK"],"prefix":"10.1016","volume":"315","author":[{"given":"Qinhang","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuelin","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuolin","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruijun","family":"Ni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0058-0354","authenticated-orcid":false,"given":"Guangming","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.jep.2023.116644_bib1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s11912-021-01038-6","article-title":"Emerging therapeutics for patients with triple-negative breast cancer","volume":"23","author":"Agostinetto","year":"2021","journal-title":"Curr. Oncol. Rep."},{"issue":"9","key":"10.1016\/j.jep.2023.116644_bib2","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1002\/cm.20472","article-title":"Rho-kinase\/ROCK: a key regulator of the cytoskeleton and cell polarity","volume":"67","author":"Amano","year":"2010","journal-title":"Cytoskeleton (Hoboken)"},{"issue":"19","key":"10.1016\/j.jep.2023.116644_bib3","doi-asserted-by":"crossref","first-page":"4702","DOI":"10.1158\/1078-0432.CCR-10-0939","article-title":"Poly (ADP-Ribose) polymerase inhibition: \"targeted\" therapy for triple-negative breast cancer","volume":"16","author":"Anders","year":"2010","journal-title":"Clin. Cancer Res."},{"issue":"11","key":"10.1016\/j.jep.2023.116644_bib4","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1038\/nrclinonc.2016.66","article-title":"Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease","volume":"13","author":"Bianchini","year":"2016","journal-title":"Nat. Rev. Clin. Oncol."},{"issue":"6","key":"10.1016\/j.jep.2023.116644_bib5","first-page":"394","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"Bray","year":"2018","journal-title":"Ca - Cancer J. Clin."},{"issue":"21","key":"10.1016\/j.jep.2023.116644_bib6","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1001\/jama.295.21.2492","article-title":"Race, breast cancer subtypes, and survival in the Carolina breast cancer study","volume":"295","author":"Carey","year":"2006","journal-title":"JAMA"},{"issue":"21","key":"10.1016\/j.jep.2023.116644_bib7","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232113334","article-title":"Potential focal adhesion kinase inhibitors in management of cancer: therapeutic opportunities from herbal medicine","volume":"23","author":"Chen","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.jep.2023.116644_bib8","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1124\/jpet.121.000584","article-title":"A novel integrated pharmacokinetic-pharmacodynamic model to evaluate combination therapy and determine in vivo synergism","volume":"377","author":"Choi","year":"2021","journal-title":"J. Pharmacol. Exp. Therapeut."},{"issue":"3","key":"10.1016\/j.jep.2023.116644_bib9","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1124\/pr.58.3.10","article-title":"Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies","volume":"58","author":"Chou","year":"2006","journal-title":"Pharmacol. Rev."},{"issue":"2","key":"10.1016\/j.jep.2023.116644_bib10","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1158\/0008-5472.CAN-09-1947","article-title":"Drug combination studies and their synergy quantification using the Chou-Talalay method","volume":"70","author":"Chou","year":"2010","journal-title":"Cancer Res."},{"key":"10.1016\/j.jep.2023.116644_bib11","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.synres.2018.04.001","article-title":"The combination index (CI < 1) as the definition of synergism and of synergy claims","volume":"7","author":"Chou","year":"2018","journal-title":"Synergy"},{"issue":"20","key":"10.1016\/j.jep.2023.116644_bib12","doi-asserted-by":"crossref","first-page":"jcs259089","DOI":"10.1242\/jcs.259089","article-title":"New insights into FAK structure and function in focal adhesions","volume":"135","author":"Coq","year":"2022","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.jep.2023.116644_bib13","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.ctrv.2016.12.010","article-title":"Targeting epidermal growth factor receptor in triple negative breast cancer: new discoveries and practical insights for drug development","volume":"53","author":"Costa","year":"2017","journal-title":"Cancer Treat Rev."},{"issue":"1\u20132","key":"10.1016\/j.jep.2023.116644_bib14","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.jep.2005.05.011","article-title":"Plants as a source of anti-cancer agents","volume":"100","author":"Cragg","year":"2005","journal-title":"J. Ethnopharmacol."},{"issue":"9","key":"10.1016\/j.jep.2023.116644_bib15","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.3390\/cells10092443","article-title":"Fibronectin: molecular structure, fibrillar structure and mechanochemical signaling","volume":"10","author":"Dalton","year":"2021","journal-title":"CELLS-BASEL"},{"issue":"8","key":"10.1016\/j.jep.2023.116644_bib16","doi-asserted-by":"crossref","first-page":"667","DOI":"10.2174\/1568009622666220317091723","article-title":"Current treatment and future trends of immunotherapy in breast cancer","volume":"22","author":"Elliott","year":"2022","journal-title":"Curr. Cancer Drug Targets"},{"issue":"5","key":"10.1016\/j.jep.2023.116644_bib17","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.cell.2011.11.016","article-title":"Cancer invasion and the microenvironment: plasticity and reciprocity","volume":"147","author":"Friedl","year":"2011","journal-title":"Cell"},{"issue":"19","key":"10.1016\/j.jep.2023.116644_bib18","doi-asserted-by":"crossref","first-page":"4889","DOI":"10.3390\/cancers13194889","article-title":"DJ4 targets the Rho-associated protein kinase pathway and attenuates disease progression in preclinical murine models of acute myeloid leukemia","volume":"13","author":"Golla","year":"2021","journal-title":"Cancers"},{"issue":"3","key":"10.1016\/j.jep.2023.116644_bib19","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.cell.2005.02.022","article-title":"Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells","volume":"121","author":"Gomes","year":"2005","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.jep.2023.116644_bib20","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1042\/BJ20070146","article-title":"Co-operative Cdc42 and Rho signalling mediates ephrinB-triggered endothelial cell retraction","volume":"404","author":"Groeger","year":"2007","journal-title":"Biochem. J."},{"key":"10.1016\/j.jep.2023.116644_bib21","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.ejmech.2013.10.048","article-title":"Advances in the studies of roles of Rho\/Rho-kinase in diseases and the development of its inhibitors","volume":"70","author":"Guan","year":"2013","journal-title":"Eur. J. Med. Chem."},{"issue":"16","key":"10.1016\/j.jep.2023.116644_bib22","first-page":"2493","article-title":"Clinical research and pharmacology study on Sanyin decoction in the treatment of triple-negative breast cancer","volume":"16","author":"Hao","year":"2021","journal-title":"World Chin. Med."},{"issue":"8","key":"10.1016\/j.jep.2023.116644_bib23","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1111\/j.1349-7006.2000.tb01018.x","article-title":"Y-27632, an inhibitor of rho-associated protein kinase, suppresses tumor cell invasion via regulation of focal adhesion and focal adhesion kinase","volume":"91","author":"Imamura","year":"2000","journal-title":"Jpn. J. Cancer Res."},{"issue":"2","key":"10.1016\/j.jep.2023.116644_bib24","first-page":"69","article-title":"Global cancer statistics","volume":"61","author":"Jemal","year":"2011","journal-title":"Ca - Cancer J. Clin."},{"issue":"2","key":"10.1016\/j.jep.2023.116644_bib25","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.canlet.2015.03.017","article-title":"The regulatory roles of ROCK and MRCK kinases in the plasticity of cancer cell migration","volume":"361","author":"Kale","year":"2015","journal-title":"Cancer Lett."},{"issue":"19","key":"10.1016\/j.jep.2023.116644_bib26","first-page":"299","article-title":"DJ4, a novel ROCK and MRCK inhibitor, potently inhibits migration and invasion of cancer cells","volume":"74","author":"Kale","year":"2014","journal-title":"Cancer Res."},{"issue":"4","key":"10.1016\/j.jep.2023.116644_bib27","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1074\/jbc.272.4.2534","article-title":"Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol\u00ae)","volume":"272","author":"Kowalski","year":"1997","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.jep.2023.116644_bib28","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1128\/MCB.18.1.130","article-title":"Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization","volume":"18","author":"Leung","year":"1998","journal-title":"Mol. Cell Biol."},{"issue":"4","key":"10.1016\/j.jep.2023.116644_bib29","first-page":"1037","article-title":"Inhibition of Sijunzi decoction extract on human breast cancer cells MDA-MB-468","volume":"51","author":"Li","year":"2020","journal-title":"Chinese Herb. Med"},{"key":"10.1016\/j.jep.2023.116644_bib30","series-title":"Study on the Chemical Constituents and the Antioxidant Activity of Flavanols from Tripterygium wilfordii","first-page":"1","author":"Li","year":"2022"},{"issue":"1","key":"10.1016\/j.jep.2023.116644_bib31","first-page":"63","article-title":"Reverse effect and mechanism of effective components of Zhuidu Fang on triple negative breast cancer MDA-MB-231 drug-resistant cells","volume":"35","author":"Liu","year":"2019","journal-title":"J. Nanjing Univ. Tradit. Chin. Med."},{"issue":"2","key":"10.1016\/j.jep.2023.116644_bib32","first-page":"111","article-title":"Clinical research on the inhibition of recurrence and metastasis of triple negative breast cancer with the method of detoxification and blood stasis dissipating","volume":"32","author":"Liu","year":"2016","journal-title":"J. Nanjing Univ. Tradit. Chin. Med."},{"issue":"3","key":"10.1016\/j.jep.2023.116644_bib33","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.intimp.2011.01.012","article-title":"Triptolide and its expanding multiple pharmacological functions","volume":"11","author":"Liu","year":"2011","journal-title":"Int. Immunopharm."},{"issue":"17","key":"10.1016\/j.jep.2023.116644_bib34","doi-asserted-by":"crossref","first-page":"4280","DOI":"10.3390\/cancers14174280","article-title":"Challenges for triple negative breast cancer treatment: defeating heterogeneity and cancer stemness","volume":"14","author":"Mahmoud","year":"2022","journal-title":"Cancers"},{"issue":"5","key":"10.1016\/j.jep.2023.116644_bib35","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.clbc.2020.12.011","article-title":"Advances in therapeutic approaches for triple-negative breast cancer","volume":"21","author":"Mahtani","year":"2021","journal-title":"Clin. Breast Cancer"},{"issue":"3","key":"10.1016\/j.jep.2023.116644_bib36","doi-asserted-by":"crossref","first-page":"662","DOI":"10.3390\/cells10030662","article-title":"Collagen assembly at the cell surface: dogmas revisited","volume":"10","author":"Musiime","year":"2021","journal-title":"CELLS-BASEL"},{"issue":"7","key":"10.1016\/j.jep.2023.116644_bib37","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1046\/j.1365-2443.2000.00348.x","article-title":"Phosphorylation of ERM proteins at filopodia induced by Cdc42","volume":"5","author":"Nakamura","year":"2000","journal-title":"Gene Cell."},{"issue":"1","key":"10.1016\/j.jep.2023.116644_bib38","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0092-8674(95)90370-4","article-title":"Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia","volume":"81","author":"Nobes","year":"1995","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.jep.2023.116644_bib39","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.canlet.2012.01.039","article-title":"Dasatinib synergizes with both cytotoxic and signal transduction inhibitors in heterogeneous breast cancer cell lines-lessons for design of combination targeted therapy","volume":"320","author":"Park","year":"2012","journal-title":"Cancer Lett."},{"issue":"1","key":"10.1016\/j.jep.2023.116644_bib40","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1158\/1078-0432.CCR-14-0827","article-title":"Molecular pathways: targeting the kinase effectors of Rho-family GTPases","volume":"21","author":"Prudnikova","year":"2015","journal-title":"Clin. Cancer Res."},{"issue":"3","key":"10.1016\/j.jep.2023.116644_bib41","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/j.1745-7254.2005.00059.x","article-title":"Small guanine nucleotide-binding protein Rho and myocardial function","volume":"26","author":"Ren","year":"2005","journal-title":"Acta Pharmacol. Sin."},{"issue":"3","key":"10.1016\/j.jep.2023.116644_bib42","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0092-8674(92)90163-7","article-title":"The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors","volume":"70","author":"Ridley","year":"1992","journal-title":"Cell"},{"issue":"8","key":"10.1016\/j.jep.2023.116644_bib43","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1038\/ncb1019","article-title":"Differing modes of tumour cell invasion have distinct requirements for Rho\/ROCK signalling and extracellular proteolysis","volume":"5","author":"Sahai","year":"2003","journal-title":"Nat. Cell Biol."},{"issue":"1","key":"10.1016\/j.jep.2023.116644_bib44","first-page":"63","article-title":"The medicinal properties and clinical application of Taxus chinensis in traditional Chinese medicine","volume":"9","author":"Shi","year":"2018","journal-title":"New Drugs Clin. Rem."},{"key":"10.1016\/j.jep.2023.116644_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.critrevonc.2019.102855","article-title":"Triple negative breast cancer: a thorough review of biomarkers","volume":"145","author":"Silva","year":"2020","journal-title":"Crit. Rev. Oncol. Hematol."},{"issue":"1","key":"10.1016\/j.jep.2023.116644_bib46","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1152\/physrev.2001.81.1.153","article-title":"Small GTP-binding proteins","volume":"81","author":"Takai","year":"2001","journal-title":"Physiol. Rev."},{"issue":"12","key":"10.1016\/j.jep.2023.116644_bib47","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.3390\/ph14121318","article-title":"Growth inhibitory efficacy of Chinese herbs in a cellular model for triple-negative breast cancer","volume":"14","author":"Telang","year":"2021","journal-title":"Pharmaceuticals"},{"issue":"2","key":"10.1016\/j.jep.2023.116644_bib48","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1161\/01.RES.0000200162.94463.d7","article-title":"Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response","volume":"98","author":"Tzima","year":"2006","journal-title":"Circ. Res."},{"issue":"11","key":"10.1016\/j.jep.2023.116644_bib49","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1038\/nrm2786","article-title":"Non-muscle myosin II takes centre stage in cell adhesion and migration","volume":"10","author":"Vicente-Manzanares","year":"2009","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"4","key":"10.1016\/j.jep.2023.116644_bib50","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1080\/10799893.2020.1817074","article-title":"Fibronectin and colorectal cancer: signaling pathways and clinical implications","volume":"41","author":"Wang","year":"2021","journal-title":"J. Recept. Signal Transduct. Res."},{"issue":"3","key":"10.1016\/j.jep.2023.116644_bib51","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/ncb1230","article-title":"Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasion","volume":"7","author":"Wilkinson","year":"2005","journal-title":"Nat. Cell Biol."},{"issue":"2","key":"10.1016\/j.jep.2023.116644_bib52","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1083\/jcb.200209006","article-title":"Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis","volume":"160","author":"Wolf","year":"2003","journal-title":"J. Cell Biol."},{"issue":"6","key":"10.1016\/j.jep.2023.116644_bib53","first-page":"1356","article-title":"Application of dry ecdysis in treatment of small cell lung cancer","volume":"37","author":"Xue","year":"2019","journal-title":"Chin. Arch. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2023.116644_bib54","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.1040311","article-title":"Functional and clinical characteristics of focal adhesion kinases in cancer progression","volume":"10","author":"Zhang","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"issue":"5","key":"10.1016\/j.jep.2023.116644_bib55","doi-asserted-by":"crossref","first-page":"559","DOI":"10.3892\/br.2016.769","article-title":"Multiple effects of Xihuang pill aqueous extract on the Hs578T triple-negative breast cancer cell line","volume":"5","author":"Zheng","year":"2016","journal-title":"Biomed Rep"},{"issue":"4","key":"10.1016\/j.jep.2023.116644_bib56","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1080\/14786419.2017.1315575","article-title":"Anti-proliferative and pro-apoptotic effects of cinobufagin on human breast cancer MCF-7 cells and its molecular mechanism","volume":"32","author":"Zhu","year":"2018","journal-title":"Nat. Prod. Res."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874123005123?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874123005123?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:42:28Z","timestamp":1759945348000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874123005123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":56,"alternative-id":["S0378874123005123"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2023.116644","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Zhuidu Formula suppresses the migratory and invasive properties of triple-negative breast cancer cells via dual signaling pathways of RhoA\/ROCK and CDC42\/MRCK","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2023.116644","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"116644"}}