{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T07:34:53Z","timestamp":1793432093940,"version":"4.5.0"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001412","name":"Council of Scientific and Industrial Research, India","doi-asserted-by":"publisher","award":["OLP-0115"],"award-info":[{"award-number":["OLP-0115"]}],"id":[{"id":"10.13039\/501100001412","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.jep.2023.117382","type":"journal-article","created":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T17:42:40Z","timestamp":1698946960000},"page":"117382","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["Nyctanthes arbor-tristis bioactive extract ameliorates LPS-induced inflammation through the inhibition of NF-\u03baB signalling pathway"],"prefix":"10.1016","volume":"320","author":[{"given":"Vivek K.","family":"Sharma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prateeksha","family":"Prateeksha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6451-7154","authenticated-orcid":false,"given":"Shailendra P.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandana V.","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brahma N.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4103\/jpbs.JPBS_175_19","article-title":"Preparation of medicinal plants: basic extraction and fractionation procedures for experimental purposes","volume":"12","author":"Abubakar","year":"2020","journal-title":"J. Pharm. BioAllied Sci."},{"issue":"3","key":"10.1016\/j.jep.2023.117382_bib2","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.jep.2013.01.024","article-title":"Nyctanthes arbor-tristis Linn\u2014a critical ethnopharmacological review","volume":"146","author":"Agrawal","year":"2013","journal-title":"J. Ethnopharmacol."},{"issue":"7","key":"10.1016\/j.jep.2023.117382_bib3","doi-asserted-by":"crossref","first-page":"3293","DOI":"10.3390\/app11073293","article-title":"L-Citrulline: a non-essential amino acid with important roles in human health, applied sciences","volume":"11","author":"Aguayo","year":"2021","journal-title":"Appl. Sci."},{"issue":"8","key":"10.1016\/j.jep.2023.117382_bib4","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1038\/90609","article-title":"Toll-like receptors: critical proteins linking innate and acquired immunity","volume":"2","author":"Akira","year":"2001","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.jep.2023.117382_bib5","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.716469","article-title":"NF-\u03baB: at the borders of autoimmunity and inflammation","volume":"12","author":"Barnabei","year":"2021","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.jep.2023.117382_bib6","doi-asserted-by":"crossref","first-page":"7204","DOI":"10.18632\/oncotarget.23208","article-title":"Inflammatory responses and inflammation-associated diseases in organs","volume":"9","author":"Chen","year":"2018","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib7","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s40266-019-00660-1","article-title":"Safety of oral non-selective non-steroidal anti-inflammatory drugs in osteoarthritis: what does the literature say?","volume":"36","author":"Cooper","year":"2019","journal-title":"Drugs Aging"},{"issue":"6","key":"10.1016\/j.jep.2023.117382_bib8","doi-asserted-by":"crossref","first-page":"803","DOI":"10.4103\/0250-474X.49129","article-title":"Evaluation of CNS depressant activity of different plant parts of Nyctanthes arbortristis linn","volume":"70","author":"Das","year":"2008","journal-title":"Indian J. Pharm. Sci."},{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib9","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.jep.2007.11.034","article-title":"Anti-inflammatory and antinociceptive activity of arbortristoside-A","volume":"116","author":"Das","year":"2008","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib10","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.jep.2007.11.034","article-title":"Anti-inflammatory and antinociceptive activity of arbortristoside-A","volume":"116","author":"Das","year":"2008","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2023.117382_bib74","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1016\/j.biopha.2018.08.089","article-title":"The orofacial antinociceptive effect of Kaempferol-3-O-rutinoside, isolated from the plant Ouratea fieldingiana, on adult zebrafish (Danio rerio)","volume":"107","author":"do Nascimento","year":"2018","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2023.117382_bib11","doi-asserted-by":"crossref","first-page":"705","DOI":"10.3389\/fimmu.2019.00705","article-title":"NF-\u03baB signaling in macrophages: dynamics, crosstalk, and signal integration","volume":"10","author":"Dorrington","year":"2019","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.jep.2023.117382_bib12","doi-asserted-by":"crossref","first-page":"62","DOI":"10.3390\/separations8050062","article-title":"LC-ESI-QTOF-MS\/MS profiling and antioxidant activity of phenolics from custard apple fruit and by-products","volume":"8","author":"Du","year":"2021","journal-title":"Separations"},{"key":"10.1016\/j.jep.2023.117382_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.113295","article-title":"Kaempferol 3-O-(2G-glucosylrutinoside)-7-O-glucoside isolated from the flowers of Hosta plantaginea exerts anti-inflammatory activity via suppression of NF-\u03baB, MAPKs and Akt pathways in RAW 264.7 cells","volume":"153","author":"Fang","year":"2022","journal-title":"Biomed. Pharmacother."},{"issue":"2","key":"10.1016\/j.jep.2023.117382_bib14","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.physbeh.2005.03.018","article-title":"Basal and carrageenan-induced pain behavior in sprague\u2013dawley, lewis and fischer rats","volume":"85","author":"Fecho","year":"2005","journal-title":"Physiol. Behav."},{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib15","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1111\/j.1600-065X.2012.01097.x","article-title":"NF-\u03baB regulation: lessons from structures","volume":"246","author":"Ghosh","year":"2012","journal-title":"Immunol. Rev."},{"issue":"11","key":"10.1016\/j.jep.2023.117382_bib16","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.3390\/molecules26113435","article-title":"Enhancement of the antioxidant and skin permeation properties of betulin and its derivatives","volume":"26","author":"G\u00fcnther","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2023.117382_bib17","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jep.2018.11.003","article-title":"Sparassis crispa exerts anti-inflammatory activity via suppression of TLR-mediated NF-\u03baB and MAPK signaling pathways in LPS-induced RAW264.7 macrophage cells","volume":"231","author":"Han","year":"2019","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib18","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-51614-x","article-title":"Procyanidin A1 alleviates inflammatory response induced by LPS through NF-\u03baB, MAPK, and Nrf2\/HO-1 pathways in RAW264.7 cells","volume":"9","author":"Han","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2023.117382_bib19","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.intimp.2018.01.001","article-title":"Zerumbone suppresses the activation of inflammatory mediators in LPS-stimulated U937 macrophages through MyD88-dependent NF-\u03baB\/MAPK\/PI3K-Akt signaling pathways","volume":"55","author":"Haque","year":"2018","journal-title":"Int. Immunopharmacol."},{"issue":"9","key":"10.1016\/j.jep.2023.117382_bib20","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.2174\/092986609789055304","article-title":"Antinociceptive activity of lectins from Diocleinae seeds on acetic acid-induced writhing test in mice","volume":"16","author":"Holanda","year":"2009","journal-title":"Protein Pept. Lett."},{"key":"10.1016\/j.jep.2023.117382_bib21","article-title":"The protective role of localized nitric oxide production during inflammation may be mediated by the heme oxygenase-1\/carbon monoxide pathway","volume":"23","author":"Iwata","year":"2020","journal-title":"Biochem. Biophys. Rep."},{"issue":"5","key":"10.1016\/j.jep.2023.117382_bib22","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.3390\/ijms22052719","article-title":"The role of tumor necrosis factor alpha (TNF-\u03b1) in autoimmune disease and current TNF-\u03b1 inhibitors in therapeutics","volume":"22","author":"Jang","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"8","key":"10.1016\/j.jep.2023.117382_bib23","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1016\/j.sjbs.2016.08.001","article-title":"Characterization and quantification of flavonoid glycosides in the Prunus genus by UPLC-DAD-QTOF\/MS","volume":"25","author":"Jang","year":"2018","journal-title":"Saudi J. Biol. Sci."},{"key":"10.1016\/j.jep.2023.117382_bib24","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/826295","article-title":"Analgesic and anti-inflammatory activities of the methanolic stem bark extract of Nyctanthes arbor-tristis linn","volume":"2013","author":"Kakoti","year":"2013","journal-title":"BioMed Res. Int."},{"issue":"22","key":"10.1016\/j.jep.2023.117382_bib25","doi-asserted-by":"crossref","first-page":"3287","DOI":"10.1080\/14786419.2018.1470171","article-title":"Betulinic acid, the first lupane-type triterpenoid isolated via bioactivity-guided fractionation, and identified by spectroscopic analysis from leaves of Nyctanthes arbor-tristis: its potential biological activities in vitro assays","volume":"33","author":"Karan","year":"2019","journal-title":"Nat. Prod. Res."},{"issue":"5","key":"10.1016\/j.jep.2023.117382_bib26","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/ni.1863","article-title":"The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors","volume":"11","author":"Kawai","year":"2010","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.jep.2023.117382_bib27","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/291271","article-title":"In vitro antioxidant, antiproliferative, and phytochemical study in different extracts of Nyctanthes arbortristis flowers","volume":"2014","author":"Khanapur","year":"2014","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.jep.2023.117382_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116355","article-title":"Iridoids from Morinda lucida, (Benth.) Rubiaceae, produced analgesic and anti-inflammatory activities via agonism at the kappa and delta opioid receptors, inhibition of COX-2 besides elevation of CAT and SOD activities","volume":"309","author":"Kumatia","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2023.117382_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116851","article-title":"Anti-inflammatory effects of Allium cepa L. peel extracts via inhibition of JAK-STAT pathway in LPS-stimulated RAW264.7 cells","volume":"317","author":"Lee","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2023.117382_bib30","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1038\/s41598-020-58566-7","article-title":"Quzhou Fructus Aurantii Extract suppresses inflammation via regulation of MAPK, NF-\u03baB, and AMPK signaling pathway","volume":"10","author":"Li","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2023.117382_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114811","article-title":"Evaluation of the anti-inflammatory, antipyretic and antinociceptive activities of the hydroalcoholic extract of Rhynchospora nervosa (Vahl) Boeckeler (Cyperaceae)","volume":"284","author":"Lima Bezerra","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2023.117382_bib32","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.cotox.2017.11.002","article-title":"NF-\u03baB in oxidative stress","volume":"7","author":"Lingappan","year":"2018","journal-title":"Cur. Opin. Toxicol."},{"key":"10.1016\/j.jep.2023.117382_bib33","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.jff.2019.03.008","article-title":"Eriocitrin in combination with resveratrol ameliorates LPS-induced inflammation in RAW264. 7 cells and relieves TPA-induced mouse ear edema","volume":"56","author":"Liu","year":"2019","journal-title":"J. Funct.Foods"},{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib34","article-title":"NF-\u03baB signaling in inflammation","volume":"2","author":"Liu","year":"2017","journal-title":"Signal Transduct. Targeted Ther."},{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib35","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1146\/annurev-pathmechdis-012418-012718","article-title":"Diversity, mechanisms, and significance of macrophage plasticity","volume":"15","author":"Locati","year":"2020","journal-title":"Annu. Rev. Pathol."},{"issue":"8","key":"10.1016\/j.jep.2023.117382_bib36","doi-asserted-by":"crossref","first-page":"2674","DOI":"10.1016\/j.fertnstert.2009.11.037","article-title":"A selective cyclooxygenase-2 inhibitor suppresses the growth of endometriosis with an antiangiogenic effect in a rat model","volume":"93","author":"Machado","year":"2010","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jep.2023.117382_bib37","article-title":"Chimarr\u00e3o, terere and mate-tea in legitimate technology modes of preparation and consume: a comparative study of chemical composition, antioxidant, anti-inflammatory and anti-anxiety properties of the mostly consumed beverages of Ilex paraguariensis St","volume":"279","author":"Mesquita","year":"2021","journal-title":"Hil. J. Ethnopharmacol."},{"issue":"5","key":"10.1016\/j.jep.2023.117382_bib38","first-page":"484","article-title":"In vitro antioxidant evaluation and total phenolics of methanolic leaf extracts of Nyctanthes arbor-tristis L","volume":"11","author":"Michael","year":"2013","journal-title":"Chin. J. Nat. Med."},{"issue":"4","key":"10.1016\/j.jep.2023.117382_bib39","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s10787-011-0110-8","article-title":"Analgesic and anti-inflammatory activity of \u03b2-sitosterol isolated from Nyctanthes arbortristis leaves","volume":"20","author":"Nirmal","year":"2012","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.jep.2023.117382_bib40","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.883857","article-title":"Anti-Inflammatory activities of betulinic acid: a review","volume":"13","author":"Oliveira-Costa","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib41","first-page":"94","article-title":"Nyctanthes arbor-tristis: comprehensive review on its pharmacological, antioxidant, and anticancer activities","volume":"8","author":"Parekh","year":"2020","journal-title":"J. Appl. Biol. Biotechnol."},{"issue":"2","key":"10.1016\/j.jep.2023.117382_bib42","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.jep.2009.10.025","article-title":"Antinociceptive activity of fractions from Couroupita guianensis Aubl. leaves","volume":"127","author":"Pinheiro","year":"2010","journal-title":"J. Ethnopharmacol."},{"issue":"4","key":"10.1016\/j.jep.2023.117382_bib43","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/j.foodchem.2006.06.063","article-title":"Antioxidant and free radical scavenging activities of phenols from onion (Allium cepa)","volume":"102","author":"Prakash","year":"2007","journal-title":"Food Chem."},{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib44","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1080\/09637480601093269","article-title":"Total phenol, antioxidant and free radical scavenging activities of some medicinal plants","volume":"58","author":"Prakash","year":"2007","journal-title":"Int. J. Food Sci. Nutr."},{"issue":"2","key":"10.1016\/j.jep.2023.117382_bib45","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.foodchem.2006.12.029","article-title":"Antioxidant and free radical-scavenging activities of seeds and agri-wastes of some varieties of soybean (Glycine max)","volume":"104","author":"Prakash","year":"2007","journal-title":"Food Chem."},{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1476-9255-1-1","article-title":"The journal of inflammation","volume":"1","author":"Punchard","year":"2004","journal-title":"J. Inflamm."},{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib47","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.intimp.2011.12.001","article-title":"Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K\/Akt\/NF-\u03baB signaling pathways","volume":"12","author":"Qi","year":"2012","journal-title":"Int. Immunopharmacol."},{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib48","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0160-5402(89)90019-3","article-title":"Tail immersion test for the evaluation of a nociceptive reaction in mice: methodological considerations","volume":"21","author":"Ramabadran","year":"1989","journal-title":"J. Pharmacol. Methods"},{"key":"10.1016\/j.jep.2023.117382_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.jssc.2022.123639","article-title":"Exploring the potential of anti-inflammatory activity of berberine chloride-loaded mesoporous silica nanoparticles in carrageenan-induced rat paw edema model","volume":"317","author":"Rathod","year":"2023","journal-title":"J. Solid State Chem."},{"issue":"2","key":"10.1016\/j.jep.2023.117382_bib50","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1080\/13880200590919474","article-title":"Sedative effects of hot flower infusion of Nyctanthes arbo-tristis. On rats","volume":"43","author":"Ratnasooriya","year":"2005","journal-title":"Pharm. Biol."},{"key":"10.1016\/j.jep.2023.117382_bib51","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1146\/annurev.pathmechdis.3.121806.151456","article-title":"The inflammatory response to cell death","volume":"3","author":"Rock","year":"2008","journal-title":"Annu. Rev. Pathol."},{"issue":"2","key":"10.1016\/j.jep.2023.117382_bib52","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1111\/imm.12167","article-title":"Interleukin-1\u03b2 triggers the differentiation of macrophages with enhanced capacity to present mycobacterial antigen to T cells","volume":"141","author":"Schenk","year":"2014","journal-title":"Immunology"},{"issue":"9","key":"10.1016\/j.jep.2023.117382_bib53","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0106937","article-title":"Biosynthesis of stable antioxidant ZnO nanoparticles by Pseudomonas aeruginosa rhamnolipids","volume":"9","author":"Singh","year":"2014","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.jep.2023.117382_bib54","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.fct.2009.01.034","article-title":"Oxidative DNA damage protective activity, antioxidant and anti-quorum sensing potentials of Moringa oleifera","volume":"47","author":"Singh","year":"2009","journal-title":"Food Chem. Toxicol."},{"issue":"4","key":"10.1016\/j.jep.2023.117382_bib55","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.fct.2009.01.009","article-title":"Antioxidant and anti-quorum sensing activities of green pod of Acacia nilotica L","volume":"47","author":"Singh","year":"2009","journal-title":"Food Chem. Toxicol."},{"issue":"6","key":"10.1016\/j.jep.2023.117382_bib56","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.fct.2009.02.004","article-title":"Polyphenolics from various extracts\/fractions of red onion (Allium cepa) peel with potent antioxidant and antimutagenic activities","volume":"47","author":"Singh","year":"2009","journal-title":"Food Chem. Toxicol."},{"issue":"16","key":"10.1016\/j.jep.2023.117382_bib57","doi-asserted-by":"crossref","first-page":"6444","DOI":"10.1016\/j.biortech.2010.03.057","article-title":"Solid-state cultivation of Trichoderma harzianum NBRI-1055 for modulating natural antioxidants in soybean seed matrix","volume":"101","author":"Singh","year":"2010","journal-title":"Bioresour. Technol."},{"issue":"31","key":"10.1016\/j.jep.2023.117382_bib58","first-page":"41","article-title":"Flavonoids of Nyctanthes arbor-tristis linn","author":"Singh","year":"1965","journal-title":"Bull. Natl. Inst. Sci. India"},{"key":"10.1016\/j.jep.2023.117382_bib59","series-title":"Natural Medicinal Plants. IntechOpen, Rijeka","article-title":"Medicinal plants and its pharmacological values","author":"Smita","year":"2021"},{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib60","doi-asserted-by":"crossref","DOI":"10.1063\/5.0019632","article-title":"Evaluation of anti-oxidant and anti-inflammatory activity in leaf and flower ethanolic extracts of Nyctanthes arbor-tristis Linn","volume":"2263","author":"Soubhagya","year":"2020","journal-title":"AIP Conf. Proc."},{"issue":"2","key":"10.1016\/j.jep.2023.117382_bib61","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1021\/np50068a005","article-title":"New benzoic esters of loganin and 6\u03b2-hydroxyloganin from Nyctanthers arbor-tristis","volume":"53","author":"Srivastava","year":"1990","journal-title":"J. Nat. Prod."},{"issue":"2","key":"10.1016\/j.jep.2023.117382_bib62","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0031-9422(00)94997-5","article-title":"Iridoid glycosides from Nyctanthes arbor-tristis","volume":"32","author":"Stuppner","year":"1993","journal-title":"Phytochemistry (Elsevier)"},{"issue":"12","key":"10.1016\/j.jep.2023.117382_bib63","doi-asserted-by":"crossref","first-page":"9563","DOI":"10.1002\/jcp.26859","article-title":"BMAL1 and CLOCK proteins in regulating UVB\u2010induced apoptosis and DNA damage responses in human keratinocytes","volume":"233","author":"Sun","year":"2018","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.jep.2023.117382_bib64","article-title":"Parametric optimization and modeling of batch extraction process for extraction of betulinic acid from leaves of Vitex Negundi Linn","volume":"51","author":"Taralkar","year":"2015","journal-title":"Separ. Sci. Technol."},{"issue":"25","key":"10.1016\/j.jep.2023.117382_bib65","doi-asserted-by":"crossref","first-page":"22809","DOI":"10.1021\/acsomega.3c01717","article-title":"Involvement of the opioidergic mechanism in the analgesic potential of a novel indazolone derivative: efficacy in the management of pain, neuropathy, and inflammation using in vivo and in silico approaches","volume":"8","author":"Ullah","year":"2023","journal-title":"ACS Omega"},{"key":"10.1016\/j.jep.2023.117382_bib66","article-title":"Nyctanthes arbor-tristis ameliorated FCA-Induced experimental arthritis: a comparative study among different extracts","volume":"2017","author":"Uroos","year":"2017","journal-title":"Evid. Based Complementary Altern. Med."},{"issue":"25","key":"10.1016\/j.jep.2023.117382_bib67","first-page":"232","article-title":"Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs","volume":"231","author":"Vane","year":"1971","journal-title":"N. Biol."},{"issue":"2","key":"10.1016\/j.jep.2023.117382_bib68","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1007\/s11694-019-00033-7","article-title":"Optimization, evaluation and identification of flavonoids in Cirsium setosum (Willd.) MB by using response surface methodology","volume":"13","author":"Wang","year":"2019","journal-title":"J. Food Meas. Char."},{"issue":"5","key":"10.1016\/j.jep.2023.117382_bib69","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0197563","article-title":"Antitumor, antioxidant and anti-inflammatory activities of kaempferol and its corresponding glycosides and the enzymatic preparation of kaempferol","volume":"13","author":"Wang","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2023.117382_bib70","article-title":"Arachidonic Acid metabolism controls macrophage alternative activation through regulating oxidative phosphorylation in PPAR\u03b3 dependent manner","volume":"12","author":"Xu","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jep.2023.117382_bib71","doi-asserted-by":"crossref","DOI":"10.3389\/fmars.2022.920082","article-title":"Anti-inflammatory effect of acetone extracts from microalgae chlorella sp. WZ13 on RAW264.7 cells and TPA-induced ear edema in mice","volume":"9","author":"Yang","year":"2022","journal-title":"Front. Mar. Sci."},{"issue":"4","key":"10.1016\/j.jep.2023.117382_bib72","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1007\/s10068-017-0170-7","article-title":"Antioxidant and hepatoprotective activity of kaempferol 3-O-\u03b2-d- (2,6-di-O-\u03b1-l-rhamnopyranosyl)galactopyronoside against carbon tetrachloride-induced liver injury in mice","volume":"26","author":"Zang","year":"2017","journal-title":"Food Sci. Biotechnol."},{"issue":"1","key":"10.1016\/j.jep.2023.117382_bib73","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1172\/JCI11837","article-title":"Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity","volume":"107","author":"Zhang","year":"2001","journal-title":"J. Clin. Invest."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874123012527?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874123012527?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:44:09Z","timestamp":1759945449000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874123012527"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":74,"alternative-id":["S0378874123012527"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2023.117382","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nyctanthes arbor-tristis bioactive extract ameliorates LPS-induced inflammation through the inhibition of NF-\u03baB signalling pathway","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2023.117382","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"117382"}}