{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T11:45:45Z","timestamp":1784115945178,"version":"3.55.0"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100011604","name":"Ministry Of Health, Nutrition and Indigenous Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011604","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003583","name":"National Human Rights Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003583","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.jep.2024.117763","type":"journal-article","created":{"date-parts":[[2024,1,21]],"date-time":"2024-01-21T01:18:10Z","timestamp":1705799890000},"page":"117763","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Aqueous distillate of mature leaves of Vernonia zeylanica (L.) Less. and Mallotus repandus (Rottler) M\u00fcll. Arg. cued from traditional medicine exhibits rapid wound healing properties"],"prefix":"10.1016","volume":"324","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4936-5516","authenticated-orcid":false,"given":"Praneeth","family":"Ratnayake","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Udaya","family":"Samaratunga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inoka","family":"Perera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayamini","family":"Seneviratne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5431-0715","authenticated-orcid":false,"given":"Preethi","family":"Udagama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2024.117763_bib1","doi-asserted-by":"crossref","first-page":"879","DOI":"10.13005\/bbra\/1211","article-title":"In vitro antifungal potentials of bioactive compound methyl ester of hexadecanoic acid isolated from Annona muricata Linn. (Annonaceae) leaves","volume":"10","author":"Abubacker","year":"2013","journal-title":"Biosci. Biotechnol. Res. Asia"},{"key":"10.1016\/j.jep.2024.117763_bib2","first-page":"2035","article-title":"Bioactive components, protein quality and in vitro antioxidant properties of leaves of two medicinal Ornamental plants","volume":"9","author":"Adaeze","year":"2019","journal-title":"Asian J. Pharmaceut. Health Sci."},{"key":"10.1016\/j.jep.2024.117763_bib3","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.7150\/ijms.43986","article-title":"Fibroblast proliferation and migration in wound healing by phytochemicals: evidence for a novel synergic outcome","volume":"17","author":"Addis","year":"2020","journal-title":"Int. J. Med. Sci."},{"key":"10.1016\/j.jep.2024.117763_bib4","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jep.2011.03.073","article-title":"Ethnopharmacological survey and in vitro evaluation of wound-healing plants used in South-western Nigeria","volume":"137","author":"Adetutu","year":"2011","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117763_bib5","doi-asserted-by":"crossref","first-page":"407","DOI":"10.12968\/jowc.2013.22.8.407","article-title":"Wound healing and the role of fibroblasts","volume":"22","author":"Bainbridge","year":"2013","journal-title":"J. Wound Care"},{"key":"10.1016\/j.jep.2024.117763_bib6","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1590\/1678-4685-GMB-2015-0057","article-title":"Human mesenchymal stem cells are resistant to cytotoxic and genotoxic effects of cisplatin in vitro","volume":"39","author":"Bellagamba","year":"2016","journal-title":"Genet. Mol. Biol."},{"key":"10.1016\/j.jep.2024.117763_bib7","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1111\/jcpe.12324","article-title":"Fibroblast growth factor-2 promotes healing of surgically created periodontal defects in rats with early, streptozotocin-induced diabetes via increasing cell proliferation and regulating angiogenesis","volume":"42","author":"Bizenjima","year":"2015","journal-title":"J. Clin. Periodontol."},{"key":"10.1016\/j.jep.2024.117763_bib8","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1373\/clinchem.2008.112797","article-title":"The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments","volume":"55","author":"Bustin","year":"2009","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jep.2024.117763_bib9","first-page":"301","article-title":"Fibroblasts and myofibroblasts in wound healing","volume":"7","author":"Darby","year":"2014","journal-title":"Clin. Cosmet. Invest. Dermatol."},{"key":"10.1016\/j.jep.2024.117763_bib11","doi-asserted-by":"crossref","first-page":"491","DOI":"10.2217\/rme-2018-0073","article-title":"Fibroblasts and wound healing: an update","volume":"13","author":"Desjardins-Park","year":"2018","journal-title":"Regen. Med."},{"key":"10.1016\/j.jep.2024.117763_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphys.2019.00322","article-title":"The spectrum of scarring in craniofacial wound repair","volume":"10","author":"DesJardins-Park","year":"2019","journal-title":"Front. Physiol."},{"key":"10.1016\/j.jep.2024.117763_bib13","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/14653240600855905","article-title":"Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement","volume":"8","author":"Dominici","year":"2006","journal-title":"Cytotherapy"},{"key":"10.1016\/j.jep.2024.117763_bib14","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.cxom.2012.12.008","article-title":"Wound management and nutrition for optimal wound healing","volume":"21","author":"Dryden","year":"2013","journal-title":"Atlas Oral Maxillofac. Surg. Clin. North Am."},{"key":"10.1016\/j.jep.2024.117763_bib15","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.taap.2011.04.016","article-title":"Anti-inflammatory and antifibrotic effects of methyl palmitate","volume":"254","author":"El-Demerdash","year":"2011","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.jep.2024.117763_bib79","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/S0140-6736(05)67700-8","article-title":"Wound healing and its impairment in the diabetic foot","volume":"366","author":"Falanga","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.jep.2024.117763_bib16","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1111\/j.1524-4725.2005.31727","article-title":"Endogenous growth factors as cosmeceuticals","volume":"31","author":"Fitzpatrick","year":"2005","journal-title":"Dermatol. Surg."},{"key":"10.1016\/j.jep.2024.117763_bib17","doi-asserted-by":"crossref","first-page":"445","DOI":"10.3109\/00498258709043951","article-title":"Differential induction profile of drug-metabolizing enzymes after treatment with hypolipidaemic agents","volume":"17","author":"Fournel","year":"1987","journal-title":"Xenobiotica"},{"key":"10.1016\/j.jep.2024.117763_bib18","doi-asserted-by":"crossref","first-page":"10188","DOI":"10.1074\/jbc.271.17.10188","article-title":"Transforming growth factors \u03b21, \u03b22, and \u03b23 and their receptors are differentially regulated during normal and impaired wound healing","volume":"271","author":"Frank","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jep.2024.117763_bib19","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.cell.2017.03.042","article-title":"Stem cell lineage infidelity drives wound repair and cancer","volume":"169","author":"Ge","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.jep.2024.117763_bib20","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1016\/j.jid.2016.11.020","article-title":"Research techniques made simple: analysis of collective cell migration using the wound healing assay","volume":"137","author":"Grada","year":"2017","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jep.2024.117763_bib21","first-page":"1","article-title":"Analgesic and anti-inflammatory activities of leaf extract of mallotus repandus (Willd","author":"Hasan","year":"2014","journal-title":"Muell. Arg. Biomed Res. Int."},{"key":"10.1016\/j.jep.2024.117763_bib22","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s13596-018-0312-3","article-title":"Analgesic and anti-inflammatory activities of methanolic extract of Mallotus repandus stem in animal models","volume":"18","author":"Hasan","year":"2018","journal-title":"Orient. Pharm. Exp. Med."},{"key":"10.1016\/j.jep.2024.117763_bib23","doi-asserted-by":"crossref","DOI":"10.3390\/molecules25081939","article-title":"Higher gene expression related to wound healing by fibroblasts on silk fibroin biomaterial than on collagen","volume":"25","author":"Hashimoto","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2024.117763_bib24","series-title":"Medicinal Plants (Indigenous and Exotic) Used in Ceylon","author":"Jayaweera","year":"1982"},{"key":"10.1016\/j.jep.2024.117763_bib25","first-page":"4391","article-title":"Role of matrix metalloproteinase in wound healing","volume":"14","author":"Kandhwal","year":"2022","journal-title":"Am. J. Transl. Res."},{"key":"10.1016\/j.jep.2024.117763_bib26","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.jdermsci.2014.11.001","article-title":"Attempts to accelerate wound healing","volume":"76","author":"Kasuya","year":"2014","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.jep.2024.117763_bib27","series-title":"Antitumor AK-3A and AK-3B from Mallotus Repandus","author":"Kawashima","year":"1975"},{"key":"10.1016\/j.jep.2024.117763_bib28","first-page":"195","article-title":"Distribution of pollen types in Vernonia (Vernonieae : Compositae)","volume":"4","author":"Keeley","year":"2016","journal-title":"Am. Soc. Plant Taxon."},{"key":"10.1016\/j.jep.2024.117763_bib29","doi-asserted-by":"crossref","first-page":"228","DOI":"10.26650\/IstanbulJPharm.2020.0071","article-title":"Phytochemical profiling of the bioactive principles of Alysicarpus glumaceus (Vahl) DC. aerial parts","volume":"51","author":"Khan","year":"2021","journal-title":"\u0130stanbul J. Pharm."},{"key":"10.1016\/j.jep.2024.117763_bib30","doi-asserted-by":"crossref","first-page":"3009","DOI":"10.3390\/molecules23113009","article-title":"Effect of pentacyclic triterpenoids-rich callus extract of Chaenomeles japonica (Thunb.) Lindl. ex Spach on viability, morphology, and proliferation of normal human skin fibroblasts","volume":"23","author":"Kikowska","year":"2018","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2024.117763_bib31","first-page":"454","article-title":"Application and assessment of allogeneic fibroblasts for cell therapy","volume":"13","author":"Kouhbananinejad","year":"2018","journal-title":"Iran. J. Pathol."},{"key":"10.1016\/j.jep.2024.117763_bib32","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/S0367-326X(02)00169-7","article-title":"Wound healing activity and systemic effects of Vernonia scorpioides extract in Guinea pig","volume":"73","author":"Leite","year":"2002","journal-title":"Fitoterapia"},{"key":"10.1016\/j.jep.2024.117763_bib33","first-page":"71","article-title":"Wound-healing activity of zanthoxylum bungeanum maxim seed oil on experimentally burned rats","volume":"13","author":"Li","year":"2017","journal-title":"Phcog. Mag."},{"key":"10.1016\/j.jep.2024.117763_bib34","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0378-8741(95)01246-A","article-title":"Scavenging effects of Mallotus repandus on active oxygen species","volume":"46","author":"Lin","year":"1995","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117763_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2021.109640","article-title":"Lauric acid alleviates deoxynivalenol-induced intestinal stem cell damage by potentiating the Akt\/mTORC1\/S6K1 signaling axis","volume":"348","author":"Liu","year":"2021","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.jep.2024.117763_bib36","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.drudis.2013.11.011","article-title":"Small molecules and small molecule drugs in regenerative medicine","volume":"19","author":"Lu","year":"2014","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.jep.2024.117763_bib37","doi-asserted-by":"crossref","first-page":"223","DOI":"10.4103\/0253-7613.16567","article-title":"Evaluation of wound-healing potency of Vernonia arborea Hk","volume":"37","author":"Manjunatha","year":"2005","journal-title":"Indian J. Pharmacol."},{"key":"10.1016\/j.jep.2024.117763_bib39","doi-asserted-by":"crossref","first-page":"410","DOI":"10.2174\/1871520619666181128163359","article-title":"Isolation of a new sesquiterpene lactone from Vernonia zeylanica (L) less and its anti-proliferative effects in breast cancer cell lines","volume":"19","author":"Mendis","year":"2018","journal-title":"Anti Cancer Agents Med. Chem."},{"key":"10.1016\/j.jep.2024.117763_bib40","series-title":"In Vitro Wound Healing Potential of Stem Extract of Alternanthera Sessilis","author":"Muniandy","year":"2018"},{"key":"10.1016\/j.jep.2024.117763_bib41","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1001\/archotol.1996.01890140057011","article-title":"Transforming growth factor \u03b21 improves wound healing and random flap survival in normal and irradiated rats","volume":"122","author":"Nall","year":"1996","journal-title":"Arch. Otolaryngol. Head Neck Surg."},{"key":"10.1016\/j.jep.2024.117763_bib42","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1038\/nature05883","article-title":"Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis","volume":"447","author":"North","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.jep.2024.117763_bib43","first-page":"795","article-title":"The chemical constituents and bioactivity of the seed (fruit) extracts of buchholzia","volume":"19","author":"Ojinnaka","year":"2015","journal-title":"J. Appl. Sci. Environ. Manag."},{"key":"10.1016\/j.jep.2024.117763_bib44","first-page":"1","article-title":"Elucidation of in-vitro anti-inflammatory bioactive compounds isolated from Jatropha curcas L. plant root","volume":"15","author":"Othman","year":"2015","journal-title":"BMC Compl. Alternative Med."},{"key":"10.1016\/j.jep.2024.117763_bib45","first-page":"18","article-title":"The role of the TGF-\u03b2 family in wound healing, burns and scarring: a review","volume":"2","author":"Penn","year":"2012","journal-title":"Int. J. Burns Trauma"},{"key":"10.1016\/j.jep.2024.117763_bib46","first-page":"178","article-title":"The study of spiritual remedies in orthodox rural churches and traditional medicinal practice in Gondar Zuria district, Northwestern Ethiopia","volume":"1","author":"Ragunathan","year":"2009","journal-title":"Pharmacogn. J."},{"key":"10.1016\/j.jep.2024.117763_bib47","doi-asserted-by":"crossref","first-page":"1","DOI":"10.9734\/JPRI\/2017\/39090","article-title":"In vitro proliferation and wound healing effects of Narcissus tazetta L. bulb on primary human dermal fibroblasts","volume":"20","author":"Rameshk","year":"2018","journal-title":"J Pharm Res Int"},{"key":"10.1016\/j.jep.2024.117763_bib48","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1080\/13880200701215042","article-title":"Antinociceptive potential of the Sri Lankan endemic plant Vernonia zeylanica","volume":"45","author":"Ratnasooriya","year":"2007","journal-title":"Pharm. Biol."},{"key":"10.1016\/j.jep.2024.117763_bib49","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1007\/s12015-022-10388-y","article-title":"Therapeutic potential of skin stem cells and cells of skin origin: effects of botanical drugs derived from traditional medicine","volume":"18","author":"Ratnayake","year":"2022","journal-title":"Stem Cell Rev. Reports"},{"key":"10.1016\/j.jep.2024.117763_bib51","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1038\/nprot.2008.75","article-title":"Neutral red uptake assay for the estimation of cell viability\/cytotoxicity","volume":"3","author":"Repetto","year":"2008","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.jep.2024.117763_bib52","first-page":"1","article-title":"Assessment of cytotoxicity exerted by leaf extracts from plants of the genus Rhododendron towards epidermal keratinocytes and intestine epithelial cells","volume":"15","author":"Rezk","year":"2015","journal-title":"BMC Compl. Alternative Med."},{"key":"10.1016\/j.jep.2024.117763_bib53","doi-asserted-by":"crossref","first-page":"2624","DOI":"10.1248\/cpb.37.2624","article-title":"Tannins and related compounds. LXXXVII. Isolation and characterization of four new hydrolyzable tannins from the leaves of Mallotus repandus","volume":"37","author":"Saijo","year":"1989","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.jep.2024.117763_bib54","doi-asserted-by":"crossref","first-page":"3821","DOI":"10.1080\/14786419.2022.2149515","article-title":"In-vitro cell migration enhancing and pro-angiogenic active secondary metabolites from Jeffreycia zeylanica (L.) H. Rob., S.C. Keeley & Skvarla (Asteraceae)","volume":"37","author":"Samarasinghe","year":"2022","journal-title":"Nat. Prod. Res."},{"key":"10.1016\/j.jep.2024.117763_bib55","first-page":"19","article-title":"Ravana: a great scholar and scientist","volume":"2","author":"Sharma","year":"2000","journal-title":"J. Gampaha Wickramarachchi Ayurveda Inst."},{"key":"10.1016\/j.jep.2024.117763_bib56","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/2503950","article-title":"Wound healing and omega-6 fatty acids: from inflammation to repair","author":"Silva","year":"2018","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.jep.2024.117763_bib57","first-page":"1929","article-title":"Bioactive compounds in pinang yaki (Areca vestiaria) fruit as potential source of antifertility agent","volume":"30","author":"Simbala","year":"2017","journal-title":"Pak. J. Pharm. Sci."},{"key":"10.1016\/j.jep.2024.117763_bib59","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0232565","article-title":"An image J plugin for the high throughput image analysis of in vitro scratch wound healing assays","volume":"15","author":"Suarez-Arnedo","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2024.117763_bib60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0115524","article-title":"Expression and function of connexin 43 in Human gingival wound healing and fibroblasts","volume":"10","author":"Tarzemany","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2024.117763_bib61","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1007\/s10571-019-00738-9","article-title":"FGF2 stimulates the growth and improves the melanocytic commitment of trunk neural crest cells","volume":"40","author":"Teixeira","year":"2020","journal-title":"Cell. Mol. Neurobiol."},{"issue":"3","key":"10.1016\/j.jep.2024.117763_bib62","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/(SICI)1098-2280(2000)35:3<206::AID-EM8>3.0.CO;2-J","article-title":"Single cell gel\/comet assay: guidelines for in vitro and in vivo genetic toxicology testing","volume":"35","author":"Tice","year":"2000","journal-title":"Environ. Mol. Mutagen."},{"key":"10.1016\/j.jep.2024.117763_bib63","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.jep.2013.01.040","article-title":"A review of the medicinal potentials of plants of the genus Vernonia (Asteraceae)","volume":"146","author":"Toyang","year":"2013","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.jep.2024.117763_bib64","first-page":"175","article-title":"Use of the in vivo skin comet assay to evaluate the DNA-damaging potential of chemicals applied to the skin","volume":"726","author":"Toyoizumi","year":"2011","journal-title":"MRGTEM"},{"key":"10.1016\/j.jep.2024.117763_bib65","doi-asserted-by":"crossref","first-page":"88","DOI":"10.4038\/ucr.v2i2.49","article-title":"Cues from Sri Lankan traditional medicine to the modern drug development pipeline - for a sustainable future","volume":"2","author":"Udalamaththa","year":"2021","journal-title":"Univ. Colombo Rev. (Series III)"},{"key":"10.1016\/j.jep.2024.117763_bib66","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/s13287-016-0366-4","article-title":"Potential role of herbal remedies in stem cell therapy: proliferation and differentiation of human mesenchymal stromal cells","volume":"7","author":"Udalamaththa","year":"2016","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.jep.2024.117763_bib67","article-title":"GC\u2013MS analysis of bioactive compounds from Melastomastrum capitatum (Vahl)Fern. leaf methanol extract: an anticancer plant","volume":"3","author":"Ukwubile","year":"2019","journal-title":"Sci. African"},{"key":"10.1016\/j.jep.2024.117763_bib68","first-page":"9","article-title":"Skin punch biopsy explant culture for derivation of primary human fibroblasts","author":"Vangipuram","year":"2013","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.jep.2024.117763_bib69","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1177\/147323000903700531","article-title":"The wound healing process: an overview of the cellular and molecular mechanisms","volume":"37","author":"Velnar","year":"2009","journal-title":"J. Int. Med. Res."},{"key":"10.1016\/j.jep.2024.117763_bib70","first-page":"39","article-title":"Isolation, characterization, and gene expression analysis of Wharton's jelly-derived mesenchymal stem cells under xeno-free culture conditions","volume":"4","author":"Venugopal","year":"2011","journal-title":"Stem Cells Cloning"},{"key":"10.1016\/j.jep.2024.117763_bib71","series-title":"Proceed Ing of the 2nd International Research Symposium","first-page":"1","article-title":"Biological activities of polysaccharides extracted from Vernonia cinerea and Vernonia zeylanica","author":"Wickramasinghe","year":"2018"},{"key":"10.1016\/j.jep.2024.117763_bib72","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.bbrc.2007.12.190","article-title":"Unsaturated fatty acids promote proliferation via ERK1\/2 and Akt pathway in bovine mammary epithelial cells","volume":"367","author":"Yonezawa","year":"2008","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jep.2024.117763_bib73","first-page":"123","article-title":"GC-MS analysis of phytochemical constituents in leaf extracts of Neolamarckia cadamba (rubiaceae) from Malaysia","volume":"6","author":"Zayed","year":"2014","journal-title":"Int. J. Pharm. Pharmaceut. Sci."},{"issue":"1","key":"10.1016\/j.jep.2024.117763_bib74","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s40169-018-0212-7","article-title":"Cell toxicity mechanism and biomarker","volume":"29","author":"Zhang","year":"2018","journal-title":"Clin. Transl. Med."},{"key":"10.1016\/j.jep.2024.117763_bib75","doi-asserted-by":"crossref","first-page":"324","DOI":"10.25135\/rnp.217.20.10.1854","article-title":"Chemical composition, and evaluation of antibacterial, antibiofilm and synergistic effects with conventional antibiotics of essential oil from mallotus repandus","volume":"15","author":"Zhang","year":"2021","journal-title":"Record Nat. Prod."},{"key":"10.1016\/j.jep.2024.117763_bib76","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1007\/s11458-008-0063-7","article-title":"Effect of fatty acid methyl esters from plastrum testudinis on proliferation of rat bone mesenchymal stem cells","volume":"3","author":"Zhang","year":"2008","journal-title":"Front. Chem. China"},{"key":"10.1016\/j.jep.2024.117763_bib77","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2021.153736","article-title":"A review on pharmacological activities and synergistic effect of quercetin with small molecule agents","volume":"92","author":"Zou","year":"2021","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2024.117763_bib78","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0070408","article-title":"Fetal fibroblasts and keratinocytes with immunosuppressive properties for allogeneic cell-based wound therapy","volume":"8","author":"Zuliani","year":"2013","journal-title":"PLoS One"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037887412400062X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037887412400062X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:50:34Z","timestamp":1759945834000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S037887412400062X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":75,"alternative-id":["S037887412400062X"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2024.117763","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aqueous distillate of mature leaves of Vernonia zeylanica (L.) Less. and Mallotus repandus (Rottler) M\u00fcll. Arg. cued from traditional medicine exhibits rapid wound healing properties","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2024.117763","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"117763"}}