{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T10:45:09Z","timestamp":1788432309350,"version":"build-2803163510"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.jep.2024.117839","type":"journal-article","created":{"date-parts":[[2024,2,3]],"date-time":"2024-02-03T00:04:12Z","timestamp":1706918652000},"page":"117839","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["The ethnopharmacological study of plant drugs used traditionally in Djibouti for malaria treatment"],"prefix":"10.1016","volume":"325","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5270-7425","authenticated-orcid":false,"given":"Abdirahman","family":"Elmi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5845-8263","authenticated-orcid":false,"given":"A.","family":"Said Mohamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"M\u00e9rito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9364-7289","authenticated-orcid":false,"given":"S\u00e9bastien","family":"Charneau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Amina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Grellier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Bouachrine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ata M.","family":"Lawson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatouma M.","family":"Abdoul-Latif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maha A.Y.","family":"Kordofani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2024.117839_bib1","series-title":"\u00c9tudes de l\u2019am\u00e9lioration de la performance \u00e9nerg\u00e9tique et de strat\u00e9gies de conception architecturale bioclimatique en climat chaud et humide (phdthesis)","author":"Abdou","year":"2020"},{"key":"10.1016\/j.jep.2024.117839_bib2","series-title":"Plantes m\u00e9dicinales de la R\u00e9publique de Djibouti, Editions universitaires europeennes EUE","author":"Abdoul-Latif","year":"2018"},{"key":"10.1016\/j.jep.2024.117839_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2019.111973","article-title":"Ethnobotanical survey of medicinal plants in central Abyan governorate, Yemen","volume":"241","author":"Al-Fatimi","year":"2019","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117839_bib4","doi-asserted-by":"crossref","first-page":"59","DOI":"10.2147\/JEP.S130491","article-title":"In vivo antiplasmodial activity evaluation of the leaves of Balanites rotundifolia (Van Tiegh.) Blatter (Balanitaceae) against Plasmodium berghei","volume":"9","author":"Asrade","year":"2017","journal-title":"J. Exp. Pharmacol."},{"key":"10.1016\/j.jep.2024.117839_bib5","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.641225","article-title":"The genus Eriosema (Fabaceae): from the ethnopharmacology to an evidence-based phytotherapeutic perspective?","volume":"12","author":"Ateba","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2024.117839_bib6","doi-asserted-by":"crossref","DOI":"10.21767\/2348-9502.1000014","article-title":"Survey of some common medicinal plants used in Eritrean folk medicine","volume":"4","author":"B","year":"2017","journal-title":"Am. J. Ethnomed."},{"key":"10.1016\/j.jep.2024.117839_bib7","doi-asserted-by":"crossref","first-page":"668","DOI":"10.4103\/pm.pm_100_17","article-title":"Brazilian cerrado qualea grandiflora mart. Leaves exhibit antiplasmodial and trypanocidal activities in vitro","volume":"13","author":"Cordeiro","year":"2017","journal-title":"Phcog. Mag."},{"key":"10.1016\/j.jep.2024.117839_bib8","doi-asserted-by":"crossref","first-page":"148","DOI":"10.3390\/cli10100148","article-title":"Evolution and trends of meteorological drought and wet events over the republic of Djibouti from 1961 to 2021","volume":"10","author":"Dabar","year":"2022","journal-title":"Climate"},{"key":"10.1016\/j.jep.2024.117839_bib9","first-page":"8","article-title":"Ethnobotanical survey of medicinal plants in west kordofan (Western Sudan)","volume":"11","author":"Doka","year":"2009","journal-title":"Ethnobotanical Leaflets"},{"key":"10.1016\/j.jep.2024.117839_bib10","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.indcrop.2016.09.056","article-title":"Research advances for the extraction, analysis and uses of anthraquinones: a review","volume":"94","author":"Duval","year":"2016","journal-title":"Ind. Crop. Prod."},{"key":"10.1016\/j.jep.2024.117839_bib11","doi-asserted-by":"crossref","first-page":"3046","DOI":"10.3390\/molecules26103046","article-title":"Aloe djiboutiensis: antioxidant activity, molecular networking-based approach and in vivo toxicity of this endemic species in Djibouti","volume":"26","author":"Elmi","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2024.117839_bib12","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.jep.2006.10.011","article-title":"Medicinal plants of the shinasha, agew-awi and amhara peoples in northwest Ethiopia","volume":"110","author":"Giday","year":"2007","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117839_bib13","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1055\/a-1157-9463","article-title":"Investigation of antiplasmodial effects of terpenoid compounds isolated from myrrh","volume":"86","author":"Greve","year":"2020","journal-title":"Planta Med."},{"key":"10.1016\/j.jep.2024.117839_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0240874","article-title":"In vitro analyses of Artemisia extracts on Plasmodium falciparum suggest a complex antimalarial effect","volume":"16","author":"Gruessner","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2024.117839_bib15","first-page":"77","article-title":"Aloe vera: a review of toxicity and adverse clinical effects","volume":"34","author":"Guo","year":"2016","journal-title":"J. Environ. Sci. Health C Environ. Carcinog. Ecotoxicol. Rev."},{"key":"10.1016\/j.jep.2024.117839_bib16","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.jep.2013.05.033","article-title":"Medicinal plants and their uses by the people in the Region of Randa, Djibouti","volume":"148","author":"Hassan-Abdallah","year":"2013","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117839_bib17","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s13002-018-0230-y","article-title":"Ethnobotanical investigation on medicinal plants in Algoz area (South Kordofan), Sudan","volume":"14","author":"Issa","year":"2018","journal-title":"J. Ethnobiol. Ethnomed."},{"key":"10.1016\/j.jep.2024.117839_bib18","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1080\/23818107.2020.1806106","article-title":"Ethnopharmacological approaches of the native hill people of murree and kotli sattian, district rawalpindi, province of Punjab, Pakistan","volume":"167","author":"Javed","year":"2020","journal-title":"Botany Letters"},{"key":"10.1016\/j.jep.2024.117839_bib19","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.sajb.2019.07.001","article-title":"Comparison of phytochemical profiles and antimalarial activities of Artemisia afra plant collected from five countries in Africa","volume":"125","author":"Kane","year":"2019","journal-title":"South Afr. J. Bot."},{"key":"10.1016\/j.jep.2024.117839_bib20","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.ejmech.2019.04.052","article-title":"Thiazolidinone\/thiazole based hybrids \u2013 new class of antitrypanosomal agents","volume":"174","author":"Kryshchyshyn","year":"2019","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.jep.2024.117839_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/19390210903534962","article-title":"CNS activity of aqueous extract of root of Cissus quadrangularis Linn. (Vitaceae)","volume":"7","author":"Kumar","year":"2010","journal-title":"J. Diet. Suppl."},{"key":"10.1016\/j.jep.2024.117839_bib22","doi-asserted-by":"crossref","first-page":"418","DOI":"10.2307\/3280287","article-title":"Synchronization of Plasmodium falciparum erythrocytic stages in culture","volume":"65","author":"Lambros","year":"1979","journal-title":"J. Parasitol."},{"key":"10.1016\/j.jep.2024.117839_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115008","article-title":"The relevance of quantitative ethnobotanical indices for ethnopharmacology and ethnobotany","volume":"288","author":"Leonti","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117839_bib24","article-title":"Phytochemical, antimicrobial and antiplasmodial investigations of Terminalia brownii","volume":"8","author":"Machumi","year":"2013","journal-title":"Nat. Prod. Commun."},{"key":"10.1016\/j.jep.2024.117839_bib25","doi-asserted-by":"crossref","first-page":"47","DOI":"10.4314\/mejs.v4i1.74056","article-title":"Invivo antimalarial activity of Dodonaea Angustifolia seed extracts against Plasmodium berghei in mice model","volume":"4","author":"Mengiste","year":"2012","journal-title":"Momona Ethiopian Journal of Science"},{"key":"10.1016\/j.jep.2024.117839_bib26","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.jep.2011.11.006","article-title":"Ethnobotanical study of antimalarial plants in Shinile District, Somali Region, Ethiopia, and in vivo evaluation of selected ones against Plasmodium berghei","volume":"139","author":"Mesfin","year":"2012","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117839_bib27","first-page":"52","article-title":"Antimalarial natural products: a review","volume":"2","author":"Mojab","year":"2012","journal-title":"Avicenna J Phytomed"},{"key":"10.1016\/j.jep.2024.117839_bib28","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1021\/acs.jnatprod.9b01285","article-title":"Natural products as sources of new drugs over the nearly four decades from 01\/1981 to 09\/2019","volume":"83","author":"Newman","year":"2020","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.jep.2024.117839_bib29","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.jep.2010.01.033","article-title":"Antimalarial herbal remedies of Msambweni, Kenya","volume":"128","author":"Nguta","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117839_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.9734\/EJMP\/2017\/38043","article-title":"Ethnobotanical survey of antimalarial plants in areas of: abukamola, angeta, oculokori and omarari of alebtong district in northern Uganda","volume":"21","author":"Opio","year":"2018","journal-title":"EJMP"},{"key":"10.1016\/j.jep.2024.117839_bib31","series-title":"Directives Nationales de Diagnostic et de Traitement du Paludisme","author":"Pnlp-Djibouti","year":"2019"},{"key":"10.1016\/j.jep.2024.117839_bib32","first-page":"41","article-title":"Ethnobotanical and ethnopharmaceutical studies on medicinal plants of Chifra district, Afar region, North Eastern Ethiopia","volume":"24","author":"Seifu","year":"2004","journal-title":"Ethiop. Pharmaceut. J."},{"key":"10.1016\/j.jep.2024.117839_bib33","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0378-8741(00)00369-X","article-title":"In vitro screening of Indian medicinal plants for antiplasmodial activity","volume":"74","author":"Simonsen","year":"2001","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117839_bib34","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.jep.2014.02.040","article-title":"An ethnobotanical study of indigenous knowledge on medicinal plants used by the village peoples of Thoppampatti, Dindigul district, Tamilnadu, India","volume":"153","author":"Sivasankari","year":"2014","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117839_bib35","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1111\/trf.15734","article-title":"Inactivation of Plasmodium falciparum in whole blood using the amustaline and glutathione pathogen reduction technology","volume":"60","author":"Sow","year":"2020","journal-title":"Transfusion"},{"key":"10.1016\/j.jep.2024.117839_bib36","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1186\/s12936-021-03866-0","article-title":"Antiplasmodial, antimalarial activities and toxicity of African medicinal plants: a systematic review of literature","volume":"20","author":"Tajbakhsh","year":"2021","journal-title":"Malar. J."},{"key":"10.1016\/j.jep.2024.117839_bib37","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s13002-017-0166-7","article-title":"An ethnobotanical survey of medicinal and edible plants of Yalo Woreda in Afar regional state, Ethiopia","volume":"13","author":"Teklehaymanot","year":"2017","journal-title":"J. Ethnobiol. Ethnomed."},{"key":"10.1016\/j.jep.2024.117839_bib38","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.jep.2014.06.052","article-title":"Volume, value and floristic diversity of Gabon\u05f3 s medicinal plant markets","volume":"155","author":"Towns","year":"2014","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117839_bib39","first-page":"277","article-title":"Epidemiology of the emergence and spread of drug-resistant falciparum malaria in South-East Asia and Australasia","volume":"89","author":"Verdrager","year":"1986","journal-title":"J. Trop. Med. Hyg."},{"key":"10.1016\/j.jep.2024.117839_bib40","series-title":"Plant Drug Analysis: A Thin Layer Chromatography Atlas","author":"Wagner","year":"1996"},{"key":"10.1016\/j.jep.2024.117839_bib41","first-page":"53","article-title":"A survey of the applications and use of ethnomedicinal plants and plant products for healthcare from the Ukambani region in Eastern Kenya","volume":"2","author":"Wanzala","year":"2016","journal-title":"IJEPP"},{"key":"10.1016\/j.jep.2024.117839_bib42","series-title":"State of the World's Plants 2017","year":"2017"},{"key":"10.1016\/j.jep.2024.117839_bib43","author":"World Health Organization"},{"key":"10.1016\/j.jep.2024.117839_bib44","series-title":"World Malaria Report 2018","author":"World Health Organization","year":"2018"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874124001387?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874124001387?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:44:49Z","timestamp":1759945489000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874124001387"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":44,"alternative-id":["S0378874124001387"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2024.117839","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The ethnopharmacological study of plant drugs used traditionally in Djibouti for malaria treatment","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2024.117839","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"117839"}}