{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T02:52:40Z","timestamp":1789181560573,"version":"build-2803163510"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.jep.2024.117840","type":"journal-article","created":{"date-parts":[[2024,2,3]],"date-time":"2024-02-03T11:23:19Z","timestamp":1706959399000},"page":"117840","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["A study for quality evaluation of Lysimachiae herba from different origins based on fingerprint-activity relationship modeling and multi-component content determination"],"prefix":"10.1016","volume":"325","author":[{"given":"Yongyi","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuihua","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahuan","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haijie","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5714-5281","authenticated-orcid":false,"given":"Xunhong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhichen","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianming","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2024.117840_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.155125","article-title":"Kaempferol attenuates carbon tetrachloride (CCl4)-induced hepatic fibrosis by promoting ASIC1a degradation and suppression of the ASIC1a-mediated ERS","volume":"121","author":"Cao","year":"2023","journal-title":"Phytomedicine"},{"issue":"4","key":"10.1016\/j.jep.2024.117840_bib2","first-page":"907","article-title":"Comprehensive antioxidant and anti-inflammatory activity of alcohol extracts from Chrysanthemum indicum in different areas based on entropy weight and TOPSIS methodology","volume":"46","author":"Chen","year":"2021","journal-title":"China J. Chin. Mater. Med."},{"issue":"14","key":"10.1016\/j.jep.2024.117840_bib3","first-page":"4504","article-title":"Study on identification technology of Lysimachia christinae and its local common articles and mixed articles based on HPLC fingerprint","volume":"53","author":"Chen","year":"2022","journal-title":"Chin. Tradit. Herb. Drugs"},{"key":"10.1016\/j.jep.2024.117840_bib4","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jep.2015.03.031","article-title":"Lysimachia christinae Hance regresses preestablished cholesterol gallstone in mice","volume":"166","author":"Deng","year":"2015","journal-title":"J. Ethnopharmacol."},{"issue":"15","key":"10.1016\/j.jep.2024.117840_bib5","first-page":"1331","article-title":"Effect of danshentong capsules on intrahepatic cholestasis liver injury in mice induced by ANIT","volume":"52","author":"Fan","year":"2017","journal-title":"Chin. Pharmaceut. J."},{"issue":"Pt 1","key":"10.1016\/j.jep.2024.117840_bib6","article-title":"Ginsenoside Rg1 alleviates ANIT-induced cholestatic liver injury by inhibiting hepatic inflammation and oxidative stress via SIRT1 activation","volume":"319","author":"Gao","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"20","key":"10.1016\/j.jep.2024.117840_bib7","doi-asserted-by":"crossref","first-page":"6150","DOI":"10.3390\/molecules26206150","article-title":"Antioxidant activity and anti-apoptotic effect of the small molecule procyanidin B1 in early mouse embryonic development produced by somatic cell nuclear transfer","volume":"26","author":"Gao","year":"2021","journal-title":"Molecules"},{"issue":"5","key":"10.1016\/j.jep.2024.117840_bib8","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1007\/s00204-019-02437-2","article-title":"Mechanisms and in vitro models of drug-induced cholestasis","volume":"93","author":"Gijbels","year":"2019","journal-title":"Arch. Toxicol."},{"issue":"3","key":"10.1016\/j.jep.2024.117840_bib9","first-page":"646","article-title":"Investigation on the mechanism of anti-drug-induced liver injury and related effector substances of traditional Chinese medicine from the perspective of metabolism","volume":"58","author":"Huang","year":"2023","journal-title":"Acta Pharm. Sin."},{"issue":"11","key":"10.1016\/j.jep.2024.117840_bib10","first-page":"2174","article-title":"Prediction of Herba Lysimachiae for treatment of urinary calculus by network pharmacology","volume":"37","author":"Huang","year":"2020","journal-title":"J. Guangzhou Univ. Tradit. Chin. Med."},{"issue":"8","key":"10.1016\/j.jep.2024.117840_bib11","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.3390\/antiox11081437","article-title":"Hyperoside as a potential natural product targeting oxidative stress in liver diseases","volume":"11","author":"Jang","year":"2022","journal-title":"Antioxidants"},{"issue":"8","key":"10.1016\/j.jep.2024.117840_bib12","first-page":"123","article-title":"Spectrum-effect relationship analysis between HPLC fingerprint and immunomodulatory activity of zhenqi fuzheng granules","volume":"28","author":"Jiang","year":"2021","journal-title":"Chin. J. Exp. Tradit. Med. Formulae"},{"issue":"1\u20133","key":"10.1016\/j.jep.2024.117840_bib13","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.tox.2010.05.011","article-title":"Interleukin-17 is involved in alpha-naphthylisothiocyanate-induced liver injury in mice","volume":"275","author":"Kobayashi","year":"2010","journal-title":"Toxicology"},{"key":"10.1016\/j.jep.2024.117840_bib14","series-title":"Exploring the Effect of Kaempferol-3-O-Rutinoside on the Prevention and Treatment of Liver Fibrosis Based on a Zebrafish Larval Model","author":"Kong","year":"2023"},{"issue":"2","key":"10.1016\/j.jep.2024.117840_bib15","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/bph.13669","article-title":"Afzelin ameliorates D-galactosamine and lipopolysaccharide-induced fulminant hepatic failure by modulating mitochondrial quality control and dynamics","volume":"174","author":"Lee","year":"2017","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.jep.2024.117840_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116832","article-title":"Discovery of effective combination from Renshen-Fuzi herbal pair against heart failure by spectrum-effect relationship analysis and zebrafish models","volume":"317","author":"Li","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"19","key":"10.1016\/j.jep.2024.117840_bib17","first-page":"2382","article-title":"Study on spectrum-effect relationship of antiinflammatory effect of different polar parts of Ampelopsis grossedentata in m-ice based on grey relational analysis","volume":"31","author":"Liu","year":"2020","journal-title":"China Pharm."},{"key":"10.1016\/j.jep.2024.117840_bib18","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.jpba.2019.04.003","article-title":"Structural characterization and screening of chemical markers of flavonoids in Lysimachiae Herba and Desmodii Styracifolii Herba by ultra high-performance liquid chromatography quadrupole time-of-flight tandem mass spectrometry based metabolomics approach","volume":"171","author":"Liu","year":"2019","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"8","key":"10.1016\/j.jep.2024.117840_bib19","doi-asserted-by":"crossref","first-page":"7910","DOI":"10.1007\/s11356-019-07532-6","article-title":"Ferulic acid prevents oxidative stress, inflammation, and liver injury via upregulation of Nrf2\/HO-1 signaling in methotrexate-induced rats","volume":"27","author":"Mahmoud","year":"2020","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"1","key":"10.1016\/j.jep.2024.117840_bib20","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.foodchem.2012.09.096","article-title":"Simultaneous detection of flavonoids and phenolic acids in Herba Lysimachiae and Herba Desmodii Styracifolii using liquid chromatography tandem mass spectrometry","volume":"138","author":"Sun","year":"2013","journal-title":"Food Chem."},{"issue":"4","key":"10.1016\/j.jep.2024.117840_bib21","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1517\/14728222.2016.1102889","article-title":"Recent advances in the exploration of the bile salt export pump (BSEP\/ABCB11) function","volume":"20","author":"Telbisz","year":"2016","journal-title":"Expert Opin. Ther. Targets"},{"key":"10.1016\/j.jep.2024.117840_bib22","series-title":"Investigation and Analysis of Medicinal Plant Resources in Some Areas of Guangyuan and Evaluation of the Adaptability of Herba Lysimachiae in Sichuan Province","author":"Wang","year":"2022"},{"key":"10.1016\/j.jep.2024.117840_bib23","series-title":"Study on the Active Ingredient Andpharmacological Action of Lysimachia Christinae","author":"Wang","year":"2018"},{"issue":"1","key":"10.1016\/j.jep.2024.117840_bib24","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s12906-018-2157-1","article-title":"Evaluation of the antioxidant and endothelial protective effects of Lysimachia christinae Hance (Jin Qian Cao) extract fractions","volume":"18","author":"Wu","year":"2018","journal-title":"BMC Compl. Alternative Med."},{"key":"10.1016\/j.jep.2024.117840_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.155055","article-title":"Kaempferol ameliorated alcoholic liver disease through inhibiting hepatic bile acid synthesis by targeting intestinal FXR-FGF15 signaling","volume":"120","author":"Xiao","year":"2023","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2024.117840_bib26","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.cbi.2016.01.004","article-title":"Protective effect of hyperoside against acetaminophen (APAP) induced liver injury through enhancement of APAP clearance","volume":"246","author":"Xie","year":"2016","journal-title":"Chem. Biol. Interact."},{"issue":"2","key":"10.1016\/j.jep.2024.117840_bib27","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/j.jep.2014.06.014","article-title":"The mechanism of hepatoprotective effect of sesquiterpene rich fraction from Cichorum glandulosum Boiss. et Huet on immune reaction-induced liver injury in mice","volume":"155","author":"Xin","year":"2014","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117840_bib28","series-title":"The Constituents Analysis of Lysimachia Christinae Hance and Quercetin Flavones Extracting by Using Deep Eutectic Solvents","author":"Xu","year":"2019"},{"issue":"19","key":"10.1016\/j.jep.2024.117840_bib29","first-page":"5394","article-title":"Anti-inflammatory activity of total flavonoids of Lysimachia christinae Hance","volume":"35","author":"Yan","year":"2015","journal-title":"Chin. T. Geriatr."},{"issue":"1","key":"10.1016\/j.jep.2024.117840_bib30","first-page":"18","article-title":"Oriental wormwood, radix paeoniae rubra, and Lysimachia christinae in the treatment of cholestasis or elevation of transaminase\u2014three prescription by professor TONG xiaolin","volume":"40","author":"Yang","year":"2020","journal-title":"Jilin J. of Chin. Med."},{"issue":"1","key":"10.1016\/j.jep.2024.117840_bib31","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.jep.2011.04.029","article-title":"Evaluation of Lysimachia christinae Hance extracts as anticholecystitis and cholagogic agents in animals","volume":"137","author":"Yang","year":"2011","journal-title":"J. Ethnopharmacol."},{"issue":"7","key":"10.1016\/j.jep.2024.117840_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.arabjc.2022.103933","article-title":"A study for quality evaluation of Taxilli Herba from different hosts based on fingerprint-activity relationship modeling and multivariate statistical analysis","volume":"15","author":"Yuan","year":"2022","journal-title":"Arab. J. Chem."},{"issue":"21","key":"10.1016\/j.jep.2024.117840_bib33","first-page":"1","article-title":"Application comparison of grey correlation degree and pearson correlation coefficient","volume":"20","author":"Zhang","year":"2014","journal-title":"J. Chifeng Univ."},{"issue":"2","key":"10.1016\/j.jep.2024.117840_bib34","first-page":"601","article-title":"Establishment of HPLC fingerprint of Malus doumeri and its spectrum-effect relationship of blood-activating and stasis-resolving","volume":"54","author":"Zhang","year":"2023","journal-title":"Chin. Tradit. Herb. Drugs"},{"issue":"3","key":"10.1016\/j.jep.2024.117840_bib35","first-page":"680","article-title":"Overview of the research status of the relationship between spectrum and effect of traditional Chinese medicine","volume":"33","author":"Zhang","year":"2022","journal-title":"Lishizhen Med. Mater Med. Res."},{"key":"10.1016\/j.jep.2024.117840_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2019.112966","article-title":"Xiaoyan lidan formula ameliorates \u03b1-naphthylisothiocyanate-induced intrahepatic cholestatic liver injury in rats as revealed by non-targeted and targeted metabolomics","volume":"179","author":"Zhang","year":"2020","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"8","key":"10.1016\/j.jep.2024.117840_bib37","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.2174\/1573412916999200727000551","article-title":"UPLC-MS\/MS Determination of chlorogenic acid, hyperoside and astragalin in plasma and its pharmacokinetic application in liver injury rats","volume":"17","author":"Zhang","year":"2021","journal-title":"Curr. Pharmaceut. Anal."},{"issue":"21","key":"10.1016\/j.jep.2024.117840_bib38","first-page":"6931","article-title":"Research progress on quality characteristics and formation mechanism of genuine medicinal materials","volume":"53","author":"Zhao","year":"2022","journal-title":"Chin. Tradit. Herb. Drugs"},{"issue":"22","key":"10.1016\/j.jep.2024.117840_bib39","first-page":"156","article-title":"Analysis on spectrum-effect relationship of anti-inflammatory effect of zhideke granules based on chemical pattern recognition","volume":"26","author":"Zhou","year":"2020","journal-title":"Chin. J. Exp. Tradit. Med. Formulae"},{"issue":"14","key":"10.1016\/j.jep.2024.117840_bib40","doi-asserted-by":"crossref","first-page":"4600","DOI":"10.3390\/molecules27144600","article-title":"Qualitative analysis and componential differences of chemical constituents in Lysimachiae Herba from different habitats (sichuan basin) by UFLC-triple TOF-MS\/MS","volume":"27","author":"Zhou","year":"2022","journal-title":"Molecules"},{"issue":"17","key":"10.1016\/j.jep.2024.117840_bib41","first-page":"4663","article-title":"Quality evaluation of Lysimachiae Herba from different habitats based on simultaneous determination of multiple bioactive constituents combined with multivariate statistical analysis","volume":"48","author":"Zhou","year":"2023","journal-title":"China J. Chin. Mater. Med."},{"key":"10.1016\/j.jep.2024.117840_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.jchromb.2022.123570","article-title":"Identification of Yinchenwuling fang's active components and hepatoprotective effects against cholestatic liver damage induced by alpha-naphthyl isothiocyanate in mice","volume":"1215","author":"Zou","year":"2023","journal-title":"J. Chromatogr., B: Anal. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.jep.2024.117840_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2020.107328","article-title":"An insight into the mechanism and molecular basis of dysfunctional immune response involved in cholestasis","volume":"92","author":"Zou","year":"2021","journal-title":"Int. Immunopharm."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874124001399?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874124001399?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:49:54Z","timestamp":1759945794000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874124001399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":43,"alternative-id":["S0378874124001399"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2024.117840","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A study for quality evaluation of Lysimachiae herba from different origins based on fingerprint-activity relationship modeling and multi-component content determination","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2024.117840","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"117840"}}