{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T10:17:47Z","timestamp":1778494667115,"version":"3.51.4"},"reference-count":119,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100009103","name":"Education Department of Shaanxi Provincial government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009103","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.jep.2024.117940","type":"journal-article","created":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T03:25:56Z","timestamp":1708658756000},"page":"117940","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Sambucus williamsii Hance: A comprehensive review of traditional uses, processing specifications, botany, phytochemistry, pharmacology, toxicology, and pharmacokinetics"],"prefix":"10.1016","volume":"326","author":[{"given":"Xuan","family":"Lei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuan","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingying","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiong","family":"Qu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaomei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinbo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2024.117940_bib1","volume":"ume 12","author":"Ai","year":"2013"},{"key":"10.1016\/j.jep.2024.117940_bib2","series-title":"Anhui Chinese Herbal Medicine\u00b7Botanical Medicine","year":"1975"},{"key":"10.1016\/j.jep.2024.117940_bib3","series-title":"Anhui Province Chinese Herbal Medicine Processing Specification","year":"2005"},{"key":"10.1016\/j.jep.2024.117940_bib4","series-title":"Processing Specification of Chinese Herbal Pieces in Anhui Province. Hefei, China","year":"2019"},{"key":"10.1016\/j.jep.2024.117940_bib5","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1002\/ptr.1031","article-title":"Antioxidant capacities of ten edible North American plants","volume":"16","author":"Acuna","year":"2002","journal-title":"Phytother Res."},{"key":"10.1016\/j.jep.2024.117940_bib6","doi-asserted-by":"crossref","first-page":"11033","DOI":"10.1021\/jf402838a","article-title":"Bioactive components from flowers of Sambucus nigra L. increase glucose uptake in primary porcine myotube cultures and reduce fat accumulation in Caenorhabditis elegans","volume":"61","author":"Bhattacharya","year":"2013","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jep.2024.117940_bib7","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.jep.2017.06.002","article-title":"Sambulin A and B, non-glycosidic iridoids from Sambucus ebulus, exert significant in vitro anti-inflammatory activity in LPS-induced RAW 264.7 macrophages via inhibition of MAPKs's phosphorylation","volume":"206","author":"Balkan","year":"2017","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117940_bib8","series-title":"New Compilation of Refined Materia Medica","author":"Chen","year":"2013"},{"key":"10.1016\/j.jep.2024.117940_bib9","series-title":"Chongqing Chinese Herbal Pieces Processing Specifications and Standards","year":"2006"},{"key":"10.1016\/j.jep.2024.117940_bib10","first-page":"18","article-title":"Experimental study of Sambucus williamsii Hance on anti-inflammatory and analgesia","volume":"36","author":"Dong","year":"2008","journal-title":"Acta Chin. Med. Pharmacol."},{"key":"10.1016\/j.jep.2024.117940_bib11","first-page":"45","article-title":"Analysis on nutrient composition of Sambucus williamsii Hance fruits","volume":"18","author":"Du","year":"1996","journal-title":"Resour. Sci."},{"key":"10.1016\/j.jep.2024.117940_bib12","first-page":"73","article-title":"Analysis of clinical application of 'Jiegu' traditional Chinese medicine","volume":"34","author":"Du","year":"2015","journal-title":"Inn. Mong. J. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2024.117940_bib13","series-title":"Chinese Materia Medica","year":"1999"},{"key":"10.1016\/j.jep.2024.117940_bib14","series-title":"Chinese Academy of Sciences. Flora of China","year":"1990"},{"key":"10.1016\/j.jep.2024.117940_bib15","series-title":"Structural Comparison Study of Sambucus Williamsii Hance Which Grow in Different Luminous Environment. Northeast Norm","author":"Fu","year":"2016"},{"key":"10.1016\/j.jep.2024.117940_bib16","first-page":"134","article-title":"Purification process and DPPH free radical scavenging activity of anthocyanin from Sambucus williamsii","volume":"36","author":"Feng","year":"2017","journal-title":"China Brew."},{"key":"10.1016\/j.jep.2024.117940_bib17","first-page":"32","article-title":"Study on scavenging DPPH free radical of ethanol extract from elderberry fruit in wudalianchi","volume":"9","author":"Fang","year":"2018","journal-title":"Heilongjiang Sci"},{"key":"10.1016\/j.jep.2024.117940_bib18","first-page":"37","article-title":"Experimental study on lymphocyte transformation in mice induced by Sambucus williamsii fruit oil","volume":"1","author":"Fan","year":"2002","journal-title":"Shenyang Med"},{"key":"10.1016\/j.jep.2024.117940_bib19","series-title":"Guizhou Herbal Medicine","year":"1970"},{"key":"10.1016\/j.jep.2024.117940_bib20","series-title":"Guangxi Zhuang Autonomous Region Traditional Chinese Medicine Decoction Pieces Processing Specification","year":"2007"},{"key":"10.1016\/j.jep.2024.117940_bib21","first-page":"482","article-title":"Pharmacological Mecha-nism of Sambucus williamsii Hance in promoting fracture healing","volume":"16","author":"Han","year":"2013","journal-title":"China Pharm."},{"key":"10.1016\/j.jep.2024.117940_bib22","doi-asserted-by":"crossref","first-page":"3507","DOI":"10.3390\/molecules15053507","article-title":"Antifungal effect of (+)-pinoresinol isolated from Sambucus williamsii","volume":"15","author":"Hwang","year":"2010","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2024.117940_bib23","first-page":"65","article-title":"Herbal textual research of Sambucus williamsii","volume":"39","author":"Han","year":"2022","journal-title":"Inf. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2024.117940_bib24","series-title":"Hebei Province Chinese Medicine Decoction Pieces Processing Specification","year":"2003"},{"key":"10.1016\/j.jep.2024.117940_bib25","series-title":"Quality Standard of Chinese Medicinal Materials in Hubei Province","year":"2009"},{"key":"10.1016\/j.jep.2024.117940_bib26","series-title":"Hunan Chinese Herbal Medicine Processing Specification","year":"2010"},{"key":"10.1016\/j.jep.2024.117940_bib27","series-title":"Quality Standard of Chinese Medicinal Materials in Hubei Province","year":"2018"},{"key":"10.1016\/j.jep.2024.117940_bib28","series-title":"Study on the Chemical Constituents of Sambucus Williamsii Hance and on the Preparation Process of its Compound Prescription","author":"Han","year":"2003"},{"key":"10.1016\/j.jep.2024.117940_bib29","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.3390\/molecules23061412","article-title":"Synthesis and promotion of the osteoblast proliferation effect of morroniside derivatives","volume":"23","author":"Han","year":"2018","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2024.117940_bib30","series-title":"Research of the Chemical Separation and Pharmacological Effects for Promoting Fracture Healing Effective Parts of Sambucus Williamsii Hance","author":"He","year":"2014"},{"key":"10.1016\/j.jep.2024.117940_bib31","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.bbrc.2011.06.004","article-title":"Antifungal activity of lariciresinol derived from Sambucus williamsii and their membrane-active mechanisms in Candida albicans","volume":"410","author":"Hwang","year":"2011","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jep.2024.117940_bib32","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1016\/j.biochi.2012.04.010","article-title":"(+)-Medioresinol leads to intracellular ROS accumulation and mitochondria-mediated apoptotic cell death in Candida albicans","volume":"94","author":"Hwang","year":"2012","journal-title":"Biochimie"},{"key":"10.1016\/j.jep.2024.117940_bib33","first-page":"1","article-title":"Study on antioxidant hypoglycemic and hypolipidemic activities of Sambucus williamsii seed oil","volume":"1","author":"Hu","year":"2018","journal-title":"For. By-Prod. Spec. China."},{"key":"10.1016\/j.jep.2024.117940_bib34","series-title":"Jiangxi Traditional Chinese Medicine Processing Specification","year":"1979"},{"key":"10.1016\/j.jep.2024.117940_bib35","series-title":"Jiangsu Province Processing Specifications of Chinese Herbal Pieces","year":"1980"},{"key":"10.1016\/j.jep.2024.117940_bib36","series-title":"Jiangxi Province Chinese Medicine Processing Specification","year":"1991"},{"key":"10.1016\/j.jep.2024.117940_bib37","series-title":"Jiangsu Province Processing Specifications of Chinese Herbal Pieces","year":"1992"},{"key":"10.1016\/j.jep.2024.117940_bib38","series-title":"Jiangsu Province Processing Specifications of Chinese Herbal Pieces","year":"2002"},{"key":"10.1016\/j.jep.2024.117940_bib39","series-title":"Jiangsu Province Processing Standard of Chinese Herbal Pieces","year":"2020"},{"key":"10.1016\/j.jep.2024.117940_bib40","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1080\/14786419.2017.1361948","article-title":"Chemical constituents from Sambucus williamsii Hance fruits and hepatoprotective effects in mouse hepatocytes","volume":"32","author":"Kuang","year":"2018","journal-title":"Nat. Prod. Res."},{"key":"10.1016\/j.jep.2024.117940_bib41","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.47191\/ijmscrs\/v3-i7-40","article-title":"The potential of plant extracts to substitute for nsaid drugs that can inhibit post-operative bone healing: a literature review","volume":"3","author":"Kuncorojati","year":"2023","journal-title":"Int. J. Med. Sci. Clin. Res. Stud."},{"key":"10.1016\/j.jep.2024.117940_bib43","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.3390\/molecules17021830","article-title":"Two new iridoid glycosides from the root barks of Sambucus williamsii Hance","volume":"17","author":"Kuang","year":"2012","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2024.117940_bib44","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1093\/jn\/135.4.795","article-title":"Pharmacokinetics of enterolignans in healthy men and women consuming a single dose of secoisolariciresinol diglucoside","volume":"135","author":"Kuijsten","year":"2005","journal-title":"J. Nutr."},{"key":"10.1016\/j.jep.2024.117940_bib45","series-title":"Compendium of Materia Medica\u00b7Next","author":"Li","year":"1982"},{"key":"10.1016\/j.jep.2024.117940_bib46","first-page":"1118","article-title":"Research progress on chemical constituents and pharmacological effects of Sambucus","volume":"32","author":"Li","year":"2021","journal-title":"China Pharm."},{"key":"10.1016\/j.jep.2024.117940_bib47","first-page":"103","article-title":"Study of the anti-cancer effects of Sambucus williamsii Hance fruit oil","volume":"7","author":"Li","year":"2000","journal-title":"Chin. J. Tradit. Med. Sci. Technol."},{"key":"10.1016\/j.jep.2024.117940_bib48","first-page":"127","article-title":"Effects of Sambucus williamsii Hance fruit oil on reducing plasma lipids and anti-aging","volume":"12","author":"Liu","year":"1995","journal-title":"J. Shenyang Pharm. Univ."},{"key":"10.1016\/j.jep.2024.117940_bib49","first-page":"108","article-title":"Study on the main pharmacological effects of compound Jiegumu capsule","volume":"42","author":"Liu","year":"2010","journal-title":"New Chin. Med."},{"key":"10.1016\/j.jep.2024.117940_bib50","series-title":"Standards For Chinese Medicinal Materials in Liaoning Province (Volume II)","year":"2019"},{"key":"10.1016\/j.jep.2024.117940_bib51","series-title":"Extraction of Total Flavonoids from Elderberry Leaves and its Anti-osteoporosis Effect","author":"Liu","year":"2019"},{"key":"10.1016\/j.jep.2024.117940_bib52","first-page":"68","article-title":"Active components in Sambucus williamsii and their research progress","volume":"19","author":"Liu","year":"2018","journal-title":"Heilongjiang Anim. Sci. Vet. Med."},{"key":"10.1016\/j.jep.2024.117940_bib53","first-page":"113","article-title":"Extraction technology and free radical scavenging properties of flavonoids from Sambucus williamsii Hance","volume":"5","author":"Li","year":"2010","journal-title":"China Food Addit"},{"key":"10.1016\/j.jep.2024.117940_bib54","first-page":"994","article-title":"Studies on the extraction technology of erberry leaves polysaccharide","volume":"51","author":"Liu","year":"2012","journal-title":"Hubei Agric. Sci."},{"key":"10.1016\/j.jep.2024.117940_bib55","first-page":"362","article-title":"Analysis of physical and chemical properties of elderberry polysaccharide","volume":"41","author":"Liu","year":"2012","journal-title":"Appl. Chem. Eng."},{"key":"10.1016\/j.jep.2024.117940_bib56","first-page":"1502","article-title":"Chemical constituents in Sambucus chinensis","volume":"42","author":"Li","year":"2011","journal-title":"Chin. Tradit. Herb. Drugs"},{"key":"10.1016\/j.jep.2024.117940_bib57","first-page":"91","article-title":"Volatile components among three of Sambucus","volume":"41","author":"Li","year":"2013","journal-title":"J. Northeast For. Univ."},{"key":"10.1016\/j.jep.2024.117940_bib58","series-title":"Study on Extraction and Activity of Active Components in Different Parts from Sambucus Williamsii Hance","author":"Liu","year":"2018"},{"key":"10.1016\/j.jep.2024.117940_bib59","first-page":"29","article-title":"Study on the split and anti-inflammatory effects of the effective parts of the root bark of Sambucus williamsii to promote fracture healing","volume":"33","author":"Lin","year":"2016","journal-title":"Inf. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2024.117940_bib60","first-page":"1185","article-title":"The anthocyanin profiles from Sambucus williamsi hance and analysis of its anti-transmissible gastroenteritis virus(TGEV) activity","volume":"21","author":"Lei","year":"2013","journal-title":"J. Agric. Biotechnol."},{"key":"10.1016\/j.jep.2024.117940_bib62","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1515\/ijfe-2014-0234","article-title":"Isolation of linoleic acid from Sambucus williamsii seed oil extracted by high pressure fluid and its antioxidant, antiglycemic, hypolipidemic activities","volume":"11","author":"Lv","year":"2015","journal-title":"Int. J. Food Eng."},{"key":"10.1016\/j.jep.2024.117940_bib63","first-page":"437","article-title":"Protective effect of Sambucus williamsii Hance fruit oil on acute liver injury in mice","volume":"47","author":"Lu","year":"2018","journal-title":"J. Hyg. Res."},{"key":"10.1016\/j.jep.2024.117940_bib64","first-page":"3995","article-title":"Effect of mammalian lignans on the growth of prostate cancer cell lines","volume":"21","author":"Lin","year":"2001","journal-title":"Anticancer Res."},{"key":"10.1016\/j.jep.2024.117940_bib65","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1017\/S136898000800325X","article-title":"Dietary consumption of phytochemicals and breast cancer risk in Mexican women","volume":"12","author":"Luisa","year":"2009","journal-title":"Publ. Health Nutr."},{"key":"10.1016\/j.jep.2024.117940_bib66","first-page":"127","article-title":"Study on the hypolipidemic and anti-aging effects of Sambucus williamsii oil","volume":"2","author":"Liu","year":"1995","journal-title":"J. Shenyang Pharm. Univ."},{"key":"10.1016\/j.jep.2024.117940_bib67","first-page":"105","article-title":"Microscopic characteristics and TLC identification of compound Sambucus williamsii capsule","volume":"19","author":"Mei","year":"2010","journal-title":"Chin. J. Ethnomed. Ethnopharmacy"},{"key":"10.1016\/j.jep.2024.117940_bib68","first-page":"2063","article-title":"Chemical constituents of Sambucus L. Chin","volume":"32","author":"Ma","year":"2012","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.jep.2024.117940_bib69","series-title":"Dictionary of Traditional Chinese Medicine","year":"2006"},{"key":"10.1016\/j.jep.2024.117940_bib70","first-page":"26","article-title":"Five lignans and an iridoid from Sambucus williamsii","volume":"9","author":"Ouyang","year":"2011","journal-title":"Chin. J. Nat. Med."},{"key":"10.1016\/j.jep.2024.117940_bib71","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1093\/jn\/135.3.598","article-title":"Lignans are involved in the antitumor activity of wheat bran in colon cancer SW480 cells","volume":"135","author":"Qu","year":"2005","journal-title":"J. Nutr."},{"key":"10.1016\/j.jep.2024.117940_bib72","series-title":"Shaanxi Chinese Herbal Medicine","year":"1971"},{"key":"10.1016\/j.jep.2024.117940_bib73","series-title":"The Processing Specification of Traditional Chinese Medicine Decoction Pieces in Sichuan Province","year":"2002"},{"key":"10.1016\/j.jep.2024.117940_bib74","series-title":"Shanghai Chinese Herbal Pieces Processing Specification","year":"2008"},{"key":"10.1016\/j.jep.2024.117940_bib75","series-title":"Shanghai Specification for Processing of Chinese Herbal Pieces","year":"2018"},{"key":"10.1016\/j.jep.2024.117940_bib76","series-title":"Chemical Constituents from Roots of Sambucus Williamsii Hance","author":"Song","year":"2014"},{"key":"10.1016\/j.jep.2024.117940_bib77","first-page":"4","article-title":"Chemical constituents from the roots of Sambucus williamsii Hance","volume":"31","author":"Song","year":"2014","journal-title":"Inf. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2024.117940_bib78","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.1021\/acs.jnatprod.7b00410","article-title":"Iridoid glycosides from the twigs of Sambucus williamsii var.coreana and their biological activities","volume":"80","author":"Suh","year":"2017","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.jep.2024.117940_bib79","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1016\/j.bmcl.2016.03.023","article-title":"Bioactive lignan constituents from the twigs of Sambucus williamsii","volume":"26","author":"Suh","year":"2016","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.jep.2024.117940_bib80","first-page":"187","article-title":"Comparison of volatile oil componentsin from the leaves of three varieties of Sambucus williamsii by GC-MS","volume":"35","author":"Sun","year":"2020","journal-title":"West China J. Pharm. Sci."},{"key":"10.1016\/j.jep.2024.117940_bib81","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154607","article-title":"Sambucus williamsii Hance maintains bone homeostasis in hyperglycemia-induced osteopenia by reversing oxidative stress via cGMP\/PKG signal transduction","volume":"110","author":"Shen","year":"2023","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2024.117940_bib82","first-page":"242","article-title":"Extraction flavonoids from Sambucus williamsii Hance leaves and evaluation of antioxidant activities","volume":"37","author":"Su","year":"2016","journal-title":"Sci. Technol. Food Ind."},{"key":"10.1016\/j.jep.2024.117940_bib83","first-page":"44","article-title":"Optimization of extraction process of total saponins from Sambucus williamsii Hance leaves and its antioxidant activity in mice","volume":"33","author":"Sun","year":"2022","journal-title":"China Food Addit"},{"key":"10.1016\/j.jep.2024.117940_bib84","first-page":"1593","article-title":"Effect of Sambucus polysaccharides on rat cell proliferation and insulin secretion","volume":"27","author":"Song","year":"2011","journal-title":"Chin. Pharmacol. Bull."},{"key":"10.1016\/j.jep.2024.117940_bib85","first-page":"103","article-title":"Effect of Sambucus williamsii oil on learning and memory in mice","volume":"7","author":"Shen","year":"2000","journal-title":"Chin. J. Tradit. Med. Sci. Technol."},{"key":"10.1016\/j.jep.2024.117940_bib86","first-page":"225","article-title":"Isolation and identification of chemical constituents from the fruits of Sambucus williamsii Hance","volume":"27","author":"Tang","year":"2017","journal-title":"Chin. J. Med. Chem."},{"key":"10.1016\/j.jep.2024.117940_bib87","first-page":"1936","article-title":"Research progress on chemical constituents and pharmacological activities of Sambucus plants","volume":"45","author":"Wang","year":"2023","journal-title":"Chin. Tradit. Pat. Med."},{"key":"10.1016\/j.jep.2024.117940_bib88","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115102","article-title":"Ethnobotany, phytochemistry, pharmacology, and toxicology of the genus Sambucus L.(Viburnaceae)","volume":"292","author":"Waswa","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117940_bib89","first-page":"218","article-title":"Research progress on active components and biological activities of Elderberry","volume":"43","author":"Wei","year":"2022","journal-title":"Food Res. Dev."},{"key":"10.1016\/j.jep.2024.117940_bib90","first-page":"34","article-title":"Experimental study on antipyretic, analgesic and anti-inflammatory effects of Mongolian medicine ganda garimu (Rubus rubra and Sambucus williamsii)","volume":"20","author":"Wu","year":"2014","journal-title":"J. Med. & Pharm. Chin. Minorities."},{"key":"10.1016\/j.jep.2024.117940_bib91","doi-asserted-by":"crossref","DOI":"10.3389\/fpls.2023.1179510","article-title":"Comparative chloroplast genome analysis of Sambucus L.(Viburnaceae): inference for phylogenetic relationships among the closely related Sambucus adnata Wall. ex DC Sambucus javanica Blume","volume":"14","author":"Waswa","year":"2023","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.jep.2024.117940_bib92","first-page":"112","article-title":"Analysis on the karyotypes of Sambucus williamsii hance","volume":"33","author":"Wang","year":"2005","journal-title":"J. Northeast For. Univ."},{"key":"10.1016\/j.jep.2024.117940_bib93","doi-asserted-by":"crossref","first-page":"3869","DOI":"10.3390\/molecules16053869","article-title":"Two new iridoid glycosides from the root barks of Sambucus williamsii Hance","volume":"16","author":"Wang","year":"2011","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2024.117940_bib94","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2021.796175","article-title":"Seed oil quality and cultivation of Sambucus williamsii hance as a new oil crop","volume":"8","author":"Wang","year":"2021","journal-title":"Front. Nutr."},{"key":"10.1016\/j.jep.2024.117940_bib95","first-page":"1","article-title":"Supercritical carbon dioxide extraction of Sambucus williamsii seed oil and analysis of its volatile components","volume":"179","author":"Wang","year":"2022","journal-title":"For. By-Prod. Spec. China."},{"key":"10.1016\/j.jep.2024.117940_bib96","doi-asserted-by":"crossref","DOI":"10.1016\/j.virusres.2019.197767","article-title":"Antiviral activity of Sambucus FormosanaNakai ethanol extract and related phenolic acid constituents against human coronavirus NL63","volume":"273","author":"Weng","year":"2019","journal-title":"Virus Res."},{"key":"10.1016\/j.jep.2024.117940_bib97","first-page":"105","article-title":"Study on lymphocyte transformation in mice induced by Sambucus williamsii fruit oil","volume":"S1","author":"Wang","year":"1995","journal-title":"J. Liaoning Univ., Nat. Sci. Ed."},{"key":"10.1016\/j.jep.2024.117940_bib98","series-title":"Pharmacokinetic of the Sambucus Williamsii Hance of Morroniside","author":"Weng","year":"2016"},{"key":"10.1016\/j.jep.2024.117940_bib99","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13020-016-0106-9","article-title":"Phytochemicals and potential health effects of Sambucus williamsii Hance (Jiegumu)","volume":"11","author":"Xiao","year":"2016","journal-title":"Chin. Med."},{"key":"10.1016\/j.jep.2024.117940_bib100","volume":"ume 72","author":"Xu","year":"1988"},{"key":"10.1016\/j.jep.2024.117940_bib101","first-page":"2639","article-title":"A new nortriterpenoid from Sambucus williamsii","volume":"44","author":"Xu","year":"2013","journal-title":"Chin. Tradit. Herb. Drugs"},{"key":"10.1016\/j.jep.2024.117940_bib102","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1080\/10286020.2015.1046448","article-title":"Two new phenylpropanoids and one new sesquiterpenoid from the bioactive fraction of Sambucus williamsii","volume":"17","author":"Xiao","year":"2015","journal-title":"J. Asian Nat. Prod. Res."},{"key":"10.1016\/j.jep.2024.117940_bib103","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.fitote.2014.01.012","article-title":"New lignans from the bioactive fraction of Sambucus williamsii Hance and proliferation activities on osteoblastic-like UMR106 cells","volume":"94","author":"Xiao","year":"2014","journal-title":"Fitoterapi a"},{"key":"10.1016\/j.jep.2024.117940_bib104","first-page":"2684","article-title":"Lignans isolated from stems of Sambucus williamsii and their proliferation effects on UMR106 cells","volume":"39","author":"Xu","year":"2014","journal-title":"China J. Chin. Mater. Med."},{"key":"10.1016\/j.jep.2024.117940_bib105","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.jsbmb.2014.08.002","article-title":"Vanillic acid exerts oestrogen-like activities in osteoblast-like UMR 106 cells through MAP kinase(MEK\/ERK)-mediated ER signaling pathway","volume":"144","author":"Xiao","year":"2014","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.jep.2024.117940_bib106","doi-asserted-by":"crossref","first-page":"932","DOI":"10.3389\/fphar.2018.00932","article-title":"A metabolomics study on the bone protective effects of a lignan-rich fraction from Sambucus williamsii Ramulus in aged rats","volume":"9","author":"Xiao","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2024.117940_bib107","first-page":"3269","article-title":"Study on effects of Sambucus williamsii total glycosides tablets on fracture healing and inflammation: part I","volume":"25","author":"Yang","year":"2014","journal-title":"China Pharm."},{"key":"10.1016\/j.jep.2024.117940_bib108","first-page":"1367","article-title":"Chemical constituents from roots of Sambucus williamsii(I)","volume":"45","author":"Yang","year":"2014","journal-title":"Chin. Tradit. Herb. Drugs"},{"key":"10.1016\/j.jep.2024.117940_bib109","first-page":"2799","article-title":"Effect of monosine on the activity of osteoblasts grafting","volume":"20","author":"Yuan","year":"2022","journal-title":"Cent. South Pharm."},{"key":"10.1016\/j.jep.2024.117940_bib110","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.jep.2016.05.017","article-title":"Root bark of Sambucus Williamsii Hance promotes rat femoral fracture healing by the BMP-2\/Runx2 signaling pathway","volume":"191","author":"Yang","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117940_bib111","first-page":"338","article-title":"Preliminary study on anti-inflammatory active parts and active ingredients of Sambucus williamsii Hance","volume":"23","author":"Yang","year":"2012","journal-title":"Lishizhen Med. Mater. Med. Res."},{"key":"10.1016\/j.jep.2024.117940_bib112","first-page":"3776","article-title":"Protective effect and mechanism of morroniside on TNF-\u03b1-induced MC3T3-E1 cells via inhibiting inflammation","volume":"49","author":"Yang","year":"2018","journal-title":"Chin. Tradit. Herb. Drugs"},{"key":"10.1016\/j.jep.2024.117940_bib113","first-page":"870","article-title":"Research progress in chemical constituents and biological activity of Sambucus williamsii Hance","volume":"16","author":"Zhang","year":"2014","journal-title":"Mod. Chin. Med."},{"key":"10.1016\/j.jep.2024.117940_bib114","series-title":"Zhejiang Chinese Herbal Medicine Processing Standards","year":"1977"},{"key":"10.1016\/j.jep.2024.117940_bib115","series-title":"Study on the Systemtic Classification about Sambucus in Jilin Province","author":"Zhang","year":"2016"},{"key":"10.1016\/j.jep.2024.117940_bib116","first-page":"165","article-title":"Analysis of volatile oil in Sambucus williamsii by SPME","volume":"41","author":"Zhao","year":"2013","journal-title":"Guangzhou Chem. Ind."},{"key":"10.1016\/j.jep.2024.117940_bib117","first-page":"207","article-title":"HPLC for determining contents of oleanolic acid and ursolic acid in Sambucus canadensis aurea","volume":"42","author":"Zhao","year":"2011","journal-title":"J. Shanxi Med. Univ."},{"key":"10.1016\/j.jep.2024.117940_bib118","first-page":"39","article-title":"Study on preparation of polyphenol from Sambucusnigra L. by enzymatic assisted ethanol extraction and its bioactivities","volume":"2","author":"Zhang","year":"2018","journal-title":"Flavour Fragr. Cosmet."},{"key":"10.1016\/j.jep.2024.117940_bib119","first-page":"53","article-title":"Protection of arteriovenous fistula with Sambucus williamsii decoction immersion","volume":"30","author":"Zhao","year":"2015","journal-title":"J. Nurs. Sci."},{"key":"10.1016\/j.jep.2024.117940_bib120","first-page":"115","article-title":"Volatile components and cytotoxicity of Sambucus williamsii seed oil","volume":"36","author":"Zhang","year":"2022","journal-title":"J. Univ. Jinan, Sci. Technol."},{"key":"10.1016\/j.jep.2024.117940_bib121","first-page":"1523","article-title":"Study on chemical constituents and rat-killing activity of Sambucus williamsii","volume":"24","author":"Zhang","year":"2004","journal-title":"Acta Bot. Boreali Occident. Sin."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874124002393?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874124002393?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:50:31Z","timestamp":1759945831000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874124002393"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":119,"alternative-id":["S0378874124002393"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2024.117940","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sambucus williamsii Hance: A comprehensive review of traditional uses, processing specifications, botany, phytochemistry, pharmacology, toxicology, and pharmacokinetics","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2024.117940","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"117940"}}