{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T17:23:41Z","timestamp":1788542621929,"version":"build-2803163510"},"reference-count":172,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82274324"],"award-info":[{"award-number":["82274324"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["24NSFJQ0125"],"award-info":[{"award-number":["24NSFJQ0125"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.jep.2024.117941","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T02:30:21Z","timestamp":1708396221000},"page":"117941","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Herbal medicines provide regulation against iron overload in cardiovascular diseases: Informing future applications"],"prefix":"10.1016","volume":"326","author":[{"given":"Jia","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangyan","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjun","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jep.2024.117941_bib1","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.yjmcc.2008.12.003","article-title":"Mechanisms of flavonoid protection against myocardial ischemia-reperfusion injury","volume":"46","author":"Akhlaghi","year":"2009","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.jep.2024.117941_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2022.174981","article-title":"Reduction of iron toxicity in the heart of iron-overloaded mice with natural compounds","volume":"924","author":"Alikhani","year":"2022","journal-title":"Eur. J. Pharmacol."},{"issue":"2","key":"10.1016\/j.jep.2024.117941_bib3","doi-asserted-by":"crossref","DOI":"10.4238\/gmr.15027562","article-title":"Neuroprotective effect of Amaranthus lividus and Amaranthus tricolor and their effects on gene expression of RAGE during oxidative stress in SH-SY5Y cells","volume":"15","author":"Amornrit","year":"2016","journal-title":"Genet. Mol. Res."},{"issue":"17","key":"10.1016\/j.jep.2024.117941_bib4","doi-asserted-by":"crossref","first-page":"2188","DOI":"10.2174\/1389557522666220217113719","article-title":"Developments in the antitumor activity, mechanisms of action, structural modifications, and structure-activity relationships of steroidal saponins","volume":"22","author":"An","year":"2022","journal-title":"Mini Rev. Med. Chem."},{"key":"10.1016\/j.jep.2024.117941_bib5","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.freeradbiomed.2020.07.026","article-title":"Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell","volume":"160","author":"Bai","year":"2020","journal-title":"Free Radic. Biol. Med."},{"issue":"7784","key":"10.1016\/j.jep.2024.117941_bib6","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1038\/s41586-019-1705-2","article-title":"The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis","volume":"575","author":"Bersuker","year":"2019","journal-title":"Nature"},{"issue":"10","key":"10.1016\/j.jep.2024.117941_bib7","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.116.004940","article-title":"Residual myocardial iron following intramyocardial hemorrhage during the convalescent phase of reperfused ST-segment-elevation myocardial infarction and adverse left ventricular remodeling","volume":"9","author":"Bulluck","year":"2016","journal-title":"Circ. Cardiovasc. Imaging"},{"issue":"11\u201312","key":"10.1016\/j.jep.2024.117941_bib8","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1007\/s00018-016-2194-1","article-title":"Mechanisms of ferroptosis","volume":"73","author":"Cao","year":"2016","journal-title":"Cell. Mol. Life Sci."},{"issue":"9","key":"10.1016\/j.jep.2024.117941_bib9","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1016\/j.jcmg.2017.08.027","article-title":"Persistent iron within the infarct core after ST-segment elevation myocardial infarction: implications for left ventricular remodeling and health outcomes","volume":"11","author":"Carberry","year":"2018","journal-title":"JACC Cardiovasc. Imaging"},{"issue":"3","key":"10.1016\/j.jep.2024.117941_bib10","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.ijcard.2010.09.046","article-title":"Clinical and genetic determinants of anthracycline-induced cardiac iron accumulation","volume":"154","author":"Cascales","year":"2012","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.jep.2024.117941_bib11","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.65158","article-title":"Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8","volume":"10","author":"Chang","year":"2021","journal-title":"Elife"},{"issue":"3","key":"10.1016\/j.jep.2024.117941_bib12","doi-asserted-by":"crossref","first-page":"247","DOI":"10.15252\/emmm.201505748","article-title":"Reduction in mitochondrial iron alleviates cardiac damage during injury","volume":"8","author":"Chang","year":"2016","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.jep.2024.117941_bib13","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/5430407","article-title":"Natural drugs as a treatment strategy for cardiovascular disease through the regulation of oxidative stress","volume":"2020","author":"Chang","year":"2020","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.jep.2024.117941_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.153964","article-title":"Salidroside inhibits doxorubicin-induced cardiomyopathy by modulating a ferroptosis-dependent pathway","volume":"99","author":"Chen","year":"2022","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib15","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.bbrc.2019.06.015","article-title":"Role of TLR4\/NADPH oxidase 4 pathway in promoting cell death through autophagy and ferroptosis during heart failure","volume":"516","author":"Chen","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jep.2024.117941_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.113903","article-title":"Research progress of therapeutic drugs for doxorubicin-induced cardiomyopathy","volume":"156","author":"Chen","year":"2022","journal-title":"Biomed. Pharmacother."},{"issue":"5","key":"10.1016\/j.jep.2024.117941_bib17","doi-asserted-by":"crossref","first-page":"436","DOI":"10.2174\/138955710791330909","article-title":"Perspectives on medicinal properties of benzoquinone compounds","volume":"10","author":"Dandawate","year":"2010","journal-title":"Mini Rev. Med. Chem."},{"key":"10.1016\/j.jep.2024.117941_bib18","doi-asserted-by":"crossref","DOI":"10.1038\/srep18132","article-title":"Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy","volume":"5","author":"Das","year":"2015","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib19","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20171302","article-title":"Advanced iron-overload cardiomyopathy in a genetic murine model is rescued by resveratrol therapy","volume":"38","author":"Das","year":"2018","journal-title":"Biosci. Rep."},{"issue":"10","key":"10.1016\/j.jep.2024.117941_bib20","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1002\/ptr.6134","article-title":"Protective and therapeutic potential of ginger (Zingiber officinale) extract and [6]-gingerol in cancer: a comprehensive review","volume":"32","author":"de Lima","year":"2018","journal-title":"Phytother Res."},{"issue":"4","key":"10.1016\/j.jep.2024.117941_bib21","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1152\/physrev.00022.2018","article-title":"Fundamental mechanisms of regulated cell death and implications for heart disease","volume":"99","author":"Del Re","year":"2019","journal-title":"Physiol. Rev."},{"issue":"9","key":"10.1016\/j.jep.2024.117941_bib22","doi-asserted-by":"crossref","DOI":"10.3390\/cells10092198","article-title":"Down the iron path: mitochondrial iron homeostasis and beyond","volume":"10","author":"Dietz","year":"2021","journal-title":"Cells"},{"issue":"5","key":"10.1016\/j.jep.2024.117941_bib23","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis: an iron-dependent form of nonapoptotic cell death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.jep.2024.117941_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2019.101107","article-title":"NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis","volume":"23","author":"Dodson","year":"2019","journal-title":"Redox Biol."},{"issue":"7784","key":"10.1016\/j.jep.2024.117941_bib25","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1038\/s41586-019-1707-0","article-title":"FSP1 is a glutathione-independent ferroptosis suppressor","volume":"575","author":"Doll","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.jep.2024.117941_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101483","article-title":"Identification of Frataxin as a regulator of ferroptosis","volume":"32","author":"Du","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.jep.2024.117941_bib27","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.701788","article-title":"Ferroptosis and its potential role in metabolic diseases: a curse or revitalization?","volume":"9","author":"Duan","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"4","key":"10.1016\/j.jep.2024.117941_bib28","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20040904","article-title":"The effects of resveratrol in patients with cardiovascular disease and heart failure: a narrative review","volume":"20","author":"Dyck","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2024.117941_bib29","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.abb.2018.06.001","article-title":"Carotenoids in human nutrition and health","volume":"652","author":"Eggersdorfer","year":"2018","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.jep.2024.117941_bib30","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.628988","article-title":"Baicalin prevents myocardial ischemia\/reperfusion injury through inhibiting ACSL4 mediated ferroptosis","volume":"12","author":"Fan","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2024.117941_bib31","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/j.fct.2018.09.063","article-title":"Tanshinone IIA attenuates TNF-\u03b1 induced PTX3 expression and monocyte adhesion to endothelial cells through the p38\/NF-\u03baB pathway","volume":"121","author":"Fang","year":"2018","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jep.2024.117941_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2021.174622","article-title":"Ferroportin-mediated ferroptosis involved in new-onset atrial fibrillation with LPS-induced endotoxemia","volume":"913","author":"Fang","year":"2021","journal-title":"Eur. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.jep.2024.117941_bib33","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1093\/toxres\/tfad038","article-title":"Tectorigenin relieved sepsis-induced myocardial ferroptosis by inhibiting the expression of Smad3","volume":"12","author":"Fang","year":"2023","journal-title":"Toxicol. Res."},{"issue":"7","key":"10.1016\/j.jep.2024.117941_bib34","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1073\/pnas.1821022116","article-title":"Ferroptosis as a target for protection against cardiomyopathy","volume":"116","author":"Fang","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"3","key":"10.1016\/j.jep.2024.117941_bib35","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.bbrc.2019.10.006","article-title":"Liproxstatin-1 protects the mouse myocardium against ischemia\/reperfusion injury by decreasing VDAC1 levels and restoring GPX4 levels","volume":"520","author":"Feng","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.jep.2024.117941_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2021.101156","article-title":"Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNF\u03b1-mediated apoptosis","volume":"297","author":"Fisher","year":"2021","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.jep.2024.117941_bib37","doi-asserted-by":"crossref","DOI":"10.3390\/antiox11030583","article-title":"Ruscogenin alleviates myocardial ischemia-induced ferroptosis through the activation of BCAT1\/BCAT2","volume":"11","author":"Fu","year":"2022","journal-title":"Antioxidants"},{"issue":"9","key":"10.1016\/j.jep.2024.117941_bib38","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.202105043","article-title":"Mitochondrial regulation of ferroptosis","volume":"220","author":"Gan","year":"2021","journal-title":"J. Cell Biol."},{"issue":"2","key":"10.1016\/j.jep.2024.117941_bib39","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.molcel.2018.10.042","article-title":"Role of mitochondria in ferroptosis","volume":"73","author":"Gao","year":"2019","journal-title":"Mol. Cell"},{"key":"10.1016\/j.jep.2024.117941_bib40","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/9962922","article-title":"Photobiomodulation regulation as one promising therapeutic approach for myocardial infarction","volume":"2021","author":"Gao","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"5","key":"10.1016\/j.jep.2024.117941_bib41","article-title":"Quercetin attenuates ethanol-induced iron uptake and myocardial injury by regulating the angiotensin II-L-Type calcium channel","volume":"62","author":"Guo","year":"2018","journal-title":"Mol. Nutr. Food Res."},{"issue":"6","key":"10.1016\/j.jep.2024.117941_bib42","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/j.ccell.2019.04.002","article-title":"Targeting ferroptosis to iron out cancer","volume":"35","author":"Hassannia","year":"2019","journal-title":"Cancer Cell"},{"key":"10.1016\/j.jep.2024.117941_bib43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbrc.2021.08.067","article-title":"Tanshinone IIA protects human coronary artery endothelial cells from ferroptosis by activating the NRF2 pathway","volume":"575","author":"He","year":"2021","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jep.2024.117941_bib44","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2022.961182","article-title":"A novel polysaccharide from chuanminshen violaceum and its protective effect against myocardial injury","volume":"9","author":"He","year":"2022","journal-title":"Front. Nutr."},{"key":"10.1016\/j.jep.2024.117941_bib45","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.freeradbiomed.2023.06.025","article-title":"Aloe-emodin alleviates doxorubicin-induced cardiotoxicity via inhibition of ferroptosis","volume":"206","author":"He","year":"2023","journal-title":"Free Radic. Biol. Med."},{"issue":"4","key":"10.1016\/j.jep.2024.117941_bib46","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1177\/0960327117701986","article-title":"Ellagic acid protects against arsenic trioxide-induced cardiotoxicity in rat","volume":"37","author":"Hemmati","year":"2018","journal-title":"Hum. Exp. Toxicol."},{"issue":"4","key":"10.1016\/j.jep.2024.117941_bib47","first-page":"243","article-title":"Reversal of doxorubicin-induced cardiotoxicity by using phytotherapy: a review","volume":"20","author":"Hosseini","year":"2017","journal-title":"J. Pharmacopuncture"},{"key":"10.1016\/j.jep.2024.117941_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2021.710963","article-title":"The link between ferroptosis and cardiovascular diseases: a novel target for treatment","volume":"8","author":"Hu","year":"2021","journal-title":"Front Cardiovasc Med"},{"issue":"11","key":"10.1016\/j.jep.2024.117941_bib49","doi-asserted-by":"crossref","first-page":"4152","DOI":"10.1073\/pnas.1119338109","article-title":"Disruption of ATP-binding cassette B8 in mice leads to cardiomyopathy through a decrease in mitochondrial iron export","volume":"109","author":"Ichikawa","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"17","key":"10.1016\/j.jep.2024.117941_bib50","doi-asserted-by":"crossref","DOI":"10.3390\/molecules28176403","article-title":"Plant polyphenols and their potential benefits on cardiovascular health: a review","volume":"28","author":"Iqbal","year":"2023","journal-title":"Molecules"},{"issue":"9\u201310","key":"10.1016\/j.jep.2024.117941_bib51","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s12012-023-09804-7","article-title":"Suberosin alleviates thiazolidinedione-induced cardiomyopathy in diabetic rats by inhibiting ferroptosis via modulation of ACSL4-LPCAT3 and PI3K-AKT signaling pathways","volume":"23","author":"Iqbal","year":"2023","journal-title":"Cardiovasc. Toxicol."},{"key":"10.1016\/j.jep.2024.117941_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2021.102021","article-title":"Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes","volume":"45","author":"Jang","year":"2021","journal-title":"Redox Biol."},{"key":"10.1016\/j.jep.2024.117941_bib53","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.jep.2017.08.004","article-title":"Banxia-houpu decoction restores glucose intolerance in CUMS rats through improvement of insulin signaling and suppression of NLRP3 inflammasome activation in liver and brain","volume":"209","author":"Jia","year":"2017","journal-title":"J. Ethnopharmacol."},{"issue":"19","key":"10.1016\/j.jep.2024.117941_bib54","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20194968","article-title":"Programmed cell-death by ferroptosis: antioxidants as mitigators","volume":"20","author":"Kajarabille","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.jep.2024.117941_bib55","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1161\/CIRCIMAGING.112.000133","article-title":"Chronic manifestation of postreperfusion intramyocardial hemorrhage as regional iron deposition: a cardiovascular magnetic resonance study with ex vivo validation","volume":"6","author":"Kali","year":"2013","journal-title":"Circ. Cardiovasc. Imaging"},{"issue":"7","key":"10.1016\/j.jep.2024.117941_bib56","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/jbt.21418","article-title":"Protective efficacy of ellagic acid on glycoproteins, hematological parameters, biochemical changes, and electrolytes in myocardial infarcted rats","volume":"26","author":"Kannan","year":"2012","journal-title":"J. Biochem. Mol. Toxicol."},{"issue":"9","key":"10.1016\/j.jep.2024.117941_bib57","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1089\/ars.2014.5955","article-title":"Can mitochondrial dysfunction be a predictive factor for oxidative stress in patients with obstructive sleep apnea?","volume":"21","author":"Kim","year":"2014","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.jep.2024.117941_bib58","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.freeradbiomed.2018.10.413","article-title":"Non-transferrin-bound iron transporters","volume":"133","author":"Knutson","year":"2019","journal-title":"Free Radic. Biol. Med."},{"issue":"9","key":"10.1016\/j.jep.2024.117941_bib59","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.2174\/1389450119666180605112235","article-title":"Pathological roles of iron in cardiovascular disease","volume":"19","author":"Kobayashi","year":"2018","journal-title":"Curr. Drug Targets"},{"issue":"9","key":"10.1016\/j.jep.2024.117941_bib60","doi-asserted-by":"crossref","DOI":"10.3390\/cells11091399","article-title":"The role of ferroptosis in adverse left ventricular remodeling following acute myocardial infarction","volume":"11","author":"Komai","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.jep.2024.117941_bib61","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1016\/j.freeradbiomed.2013.09.001","article-title":"The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: insights into the potential of various iron therapies to induce oxidative and nitrosative stress","volume":"65","author":"Koskenkorva-Frank","year":"2013","journal-title":"Free Radic. Biol. Med."},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib62","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1021\/acscentsci.9b01063","article-title":"GTP cyclohydrolase 1\/tetrahydrobiopterin counteract ferroptosis through lipid remodeling","volume":"6","author":"Kraft","year":"2020","journal-title":"ACS Cent. Sci."},{"issue":"6","key":"10.1016\/j.jep.2024.117941_bib63","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1007\/s12192-010-0187-9","article-title":"Caffeic acid protects rat heart mitochondria against isoproterenol-induced oxidative damage","volume":"15","author":"Kumaran","year":"2010","journal-title":"Cell Stress Chaperones"},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib64","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/nyas.13088","article-title":"Current recommendations for chelation for transfusion-dependent thalassemia","volume":"1368","author":"Kwiatkowski","year":"2016","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.jep.2024.117941_bib65","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.freeradbiomed.2018.08.010","article-title":"Mechanisms of cardiac iron homeostasis and their importance to heart function","volume":"133","author":"Lakhal-Littleton","year":"2019","journal-title":"Free Radic. Biol. Med."},{"issue":"10","key":"10.1016\/j.jep.2024.117941_bib66","doi-asserted-by":"crossref","first-page":"3164","DOI":"10.1073\/pnas.1422373112","article-title":"Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function","volume":"112","author":"Lakhal-Littleton","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"18","key":"10.1016\/j.jep.2024.117941_bib67","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1089\/ars.2011.4271","article-title":"Mammalian iron homeostasis in health and disease: uptake, storage, transport, and molecular mechanisms of action","volume":"18","author":"Lawen","year":"2013","journal-title":"Antioxidants Redox Signal."},{"issue":"2","key":"10.1016\/j.jep.2024.117941_bib68","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/s41556-020-0461-8","article-title":"Energy-stress-mediated AMPK activation inhibits ferroptosis","volume":"22","author":"Lee","year":"2020","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.jep.2024.117941_bib69","article-title":"Ferroptosis: a potential target in cardiovascular disease","volume":"9","author":"Leng","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"8","key":"10.1016\/j.jep.2024.117941_bib70","doi-asserted-by":"crossref","DOI":"10.3390\/cells10081969","article-title":"Mitochondrial ferritin: its role in physiological and pathological conditions","volume":"10","author":"Levi","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.jep.2024.117941_bib71","article-title":"Fisetin attenuates doxorubicin-induced cardiomyopathy in vivo and in vitro by inhibiting ferroptosis through SIRT1\/nrf2 signaling pathway activation","volume":"12","author":"Li","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2024.117941_bib72","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnutbio.2022.109241","article-title":"Resveratrol alleviated 5-FU-induced cardiotoxicity by attenuating GPX4 dependent ferroptosis","volume":"112","author":"Li","year":"2023","journal-title":"J. Nutr. Biochem."},{"issue":"2","key":"10.1016\/j.jep.2024.117941_bib73","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/s41419-020-2298-2","article-title":"Ferroptosis: past, present and future","volume":"11","author":"Li","year":"2020","journal-title":"Cell Death Dis."},{"issue":"4","key":"10.1016\/j.jep.2024.117941_bib74","first-page":"699","article-title":"A novel natural product, britanin, inhibits tumor growth of pancreatic cancer by suppressing nuclear factor-\u03baB activation. Cancer Chemother","volume":"85","author":"Li","year":"2020","journal-title":"Pharmacol"},{"key":"10.1016\/j.jep.2024.117941_bib75","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2021.105466","article-title":"Ferroptosis and its emerging roles in cardiovascular diseases","volume":"166","author":"Li","year":"2021","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.jep.2024.117941_bib76","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.freeradbiomed.2020.08.009","article-title":"Ferritinophagy-mediated ferroptosis is involved in sepsis-induced cardiac injury","volume":"160","author":"Li","year":"2020","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.jep.2024.117941_bib77","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2021.145968","article-title":"Resveratrol protects against myocardial ischemia-reperfusion injury via attenuating ferroptosis","volume":"808","author":"Li","year":"2022","journal-title":"Gene"},{"issue":"2","key":"10.1016\/j.jep.2024.117941_bib78","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1089\/dna.2019.5097","article-title":"Ferroptosis is involved in diabetes myocardial ischemia\/reperfusion injury through endoplasmic reticulum stress","volume":"39","author":"Li","year":"2020","journal-title":"DNA Cell Biol."},{"issue":"7","key":"10.1016\/j.jep.2024.117941_bib79","doi-asserted-by":"crossref","first-page":"3042","DOI":"10.1002\/ptr.7798","article-title":"Astragaloside IV attenuates myocardial dysfunction in diabetic cardiomyopathy rats through downregulation of CD36-mediated ferroptosis","volume":"37","author":"Li","year":"2023","journal-title":"Phytother Res."},{"issue":"5","key":"10.1016\/j.jep.2024.117941_bib80","doi-asserted-by":"crossref","DOI":"10.3390\/antiox10050667","article-title":"Targeting ferroptosis against ischemia\/reperfusion cardiac injury","volume":"10","author":"Lillo-Moya","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.jep.2024.117941_bib81","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/9523491","article-title":"Xanthohumol protects the rat myocardium against ischemia\/reperfusion injury-induced ferroptosis","volume":"2022","author":"Lin","year":"2022","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.jep.2024.117941_bib82","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2023.176031","article-title":"Licochalcone a improves cardiac functions after ischemia-reperfusion via reduction of ferroptosis in rats","volume":"957","author":"Lin","year":"2023","journal-title":"Eur. J. Pharmacol."},{"issue":"11","key":"10.1016\/j.jep.2024.117941_bib83","doi-asserted-by":"crossref","DOI":"10.3390\/biom11111667","article-title":"Gossypol acetic acid attenuates cardiac ischemia\/reperfusion injury in rats via an antiferroptotic mechanism","volume":"11","author":"Lin","year":"2021","journal-title":"Biomolecules"},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib84","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.bbrc.2018.02.061","article-title":"Puerarin protects against heart failure induced by pressure overload through mitigation of ferroptosis","volume":"497","author":"Liu","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jep.2024.117941_bib85","article-title":"Use of deep-learning assisted assessment of cardiac parameters in zebrafish to discover cyanidin chloride as a novel Keap1 inhibitor against doxorubicin-induced cardiotoxicity","author":"Liu","year":"2023","journal-title":"Adv. Sci."},{"issue":"9","key":"10.1016\/j.jep.2024.117941_bib86","article-title":"Paeonol improves angiotensin II-induced cardiac hypertrophy by suppressing ferroptosis","volume":"9","author":"Liu","year":"2023","journal-title":"Heliyon"},{"key":"10.1016\/j.jep.2024.117941_bib87","article-title":"Resveratrol attenuate myocardial injury by inhibiting ferroptosis via inducing KAT5\/GPX4 in myocardial infarction","volume":"13","author":"Liu","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib88","doi-asserted-by":"crossref","first-page":"113","DOI":"10.2174\/092986709787002862","article-title":"Role of iron deficiency and overload in the pathogenesis of diabetes and diabetic complications","volume":"16","author":"Liu","year":"2009","journal-title":"Curr. Med. Chem."},{"issue":"4","key":"10.1016\/j.jep.2024.117941_bib89","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1097\/FJC.0000000000001199","article-title":"Ferulic acid alleviates myocardial ischemia reperfusion injury via upregulating AMPK\u03b12 expression-mediated ferroptosis depression","volume":"79","author":"Liu","year":"2021","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"11","key":"10.1016\/j.jep.2024.117941_bib90","doi-asserted-by":"crossref","first-page":"2966","DOI":"10.1002\/2211-5463.13276","article-title":"Icariin inhibits hypoxia\/reoxygenation-induced ferroptosis of cardiomyocytes via regulation of the Nrf2\/HO-1 signaling pathway","volume":"11","author":"Liu","year":"2021","journal-title":"FEBS Open Bio"},{"issue":"5","key":"10.1016\/j.jep.2024.117941_bib91","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0022-2828(03)00072-5","article-title":"Differential accumulation of non-transferrin-bound iron by cardiac myocytes and fibroblasts","volume":"35","author":"Liu","year":"2003","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.jep.2024.117941_bib92","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2023.176081","article-title":"Lutein suppresses ferroptosis of cardiac microvascular endothelial cells via positive regulation of IRF in cardiac hypertrophy","author":"Liu","year":"2023","journal-title":"Eur. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.jep.2024.117941_bib93","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1002\/ehf2.13265","article-title":"Iron deficiency in heart failure","volume":"8","author":"Loncar","year":"2021","journal-title":"ESC Heart Fail"},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib94","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1080\/13880209.2021.2007269","article-title":"Britanin relieves ferroptosis-mediated myocardial ischaemia\/reperfusion damage by upregulating GPX4 through activation of AMPK\/GSK3\u03b2\/Nrf2 signalling","volume":"60","author":"Lu","year":"2022","journal-title":"Pharm. Biol."},{"key":"10.1016\/j.jep.2024.117941_bib95","article-title":"Constituents, pharmacokinetics, and pharmacology of gegen-qinlian decoction","volume":"12","author":"Lu","year":"2021","journal-title":"Front. Pharmacol."},{"issue":"7","key":"10.1016\/j.jep.2024.117941_bib96","doi-asserted-by":"crossref","first-page":"2603","DOI":"10.1007\/s11010-021-04112-6","article-title":"Astragaloside IV inhibits adriamycin-induced cardiac ferroptosis by enhancing Nrf2 signaling","volume":"476","author":"Luo","year":"2021","journal-title":"Mol. Cell. Biochem."},{"issue":"7","key":"10.1016\/j.jep.2024.117941_bib97","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1039\/C8MT00048D","article-title":"The significance, trafficking and determination of labile iron in cytosol, mitochondria and lysosomes","volume":"10","author":"Lv","year":"2018","journal-title":"Metallomics"},{"key":"10.1016\/j.jep.2024.117941_bib98","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.108767","article-title":"Tongxinluo may stabilize atherosclerotic plaque via multiple mechanisms scanning by genechip","volume":"113","author":"Ma","year":"2019","journal-title":"Biomed. Pharmacother."},{"issue":"12","key":"10.1016\/j.jep.2024.117941_bib99","doi-asserted-by":"crossref","DOI":"10.3390\/antiox10121864","article-title":"Iron overload, oxidative stress, and ferroptosis in the failing heart and liver","volume":"10","author":"Mancardi","year":"2021","journal-title":"Antioxidants"},{"issue":"7860","key":"10.1016\/j.jep.2024.117941_bib100","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1038\/s41586-021-03539-7","article-title":"DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer","volume":"593","author":"Mao","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.jep.2024.117941_bib101","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2019.116702","article-title":"Chronic iron overload intensifies atherosclerosis in apolipoprotein E deficient mice: role of oxidative stress and endothelial dysfunction","volume":"233","author":"Marques","year":"2019","journal-title":"Life Sci."},{"issue":"5","key":"10.1016\/j.jep.2024.117941_bib102","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.jinorgbio.2011.02.003","article-title":"In vitro analysis of iron chelating activity of flavonoids","volume":"105","author":"Mlad\u011bnka","year":"2011","journal-title":"J. Inorg. Biochem."},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib103","doi-asserted-by":"crossref","first-page":"3273","DOI":"10.1038\/s41467-020-16923-0","article-title":"Iron imaging in myocardial infarction reperfusion injury","volume":"11","author":"Moon","year":"2020","journal-title":"Nat. Commun."},{"issue":"11","key":"10.1016\/j.jep.2024.117941_bib104","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/j.cardfail.2010.05.009","article-title":"Iron-overload cardiomyopathy: pathophysiology, diagnosis, and treatment","volume":"16","author":"Murphy","year":"2010","journal-title":"J. Card. Fail."},{"key":"10.1016\/j.jep.2024.117941_bib105","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1016\/j.biopha.2018.04.151","article-title":"Cardioprotective effect of Amaranthus tricolor extract in isoprenaline induced myocardial damage in ovariectomized rats","volume":"103","author":"Nahar","year":"2018","journal-title":"Biomed. Pharmacother."},{"issue":"16","key":"10.1016\/j.jep.2024.117941_bib106","doi-asserted-by":"crossref","first-page":"2655","DOI":"10.1080\/10408398.2019.1653822","article-title":"Phenylpropanoids and its derivatives: biological activities and its role in food, pharmaceutical and cosmetic industries","volume":"60","author":"Neelam","year":"2020","journal-title":"Crit. Rev. Food Sci. Nutr."},{"issue":"5","key":"10.1016\/j.jep.2024.117941_bib107","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s00109-005-0029-x","article-title":"Role of L-type Ca2+ channels in iron transport and iron-overload cardiomyopathy","volume":"84","author":"Oudit","year":"2006","journal-title":"J. Mol. Med. (Berl.)"},{"issue":"6","key":"10.1016\/j.jep.2024.117941_bib108","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1111\/j.1742-7843.2008.00244.x","article-title":"Preventive effect of S-allylcysteine on membrane-bound enzymes and glycoproteins in normal and isoproterenol-induced cardiac toxicity in male Wistar rats","volume":"103","author":"Padmanabhan","year":"2008","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"issue":"2","key":"10.1016\/j.jep.2024.117941_bib109","doi-asserted-by":"crossref","first-page":"H146","DOI":"10.1152\/ajpheart.00400.2017","article-title":"Flaxseed: its bioactive components and their cardiovascular benefits","volume":"314","author":"Parikh","year":"2018","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"19","key":"10.1016\/j.jep.2024.117941_bib110","doi-asserted-by":"crossref","DOI":"10.3390\/molecules27196429","article-title":"Interactions of isoquinoline alkaloids with transition metals iron and copper","volume":"27","author":"Parvin","year":"2022","journal-title":"Molecules"},{"issue":"2","key":"10.1016\/j.jep.2024.117941_bib111","doi-asserted-by":"crossref","first-page":"101","DOI":"10.4103\/0022-3859.153104","article-title":"Heart failure: novel therapeutic approaches","volume":"61","author":"Patel","year":"2015","journal-title":"J. Postgrad. Med."},{"issue":"12","key":"10.1016\/j.jep.2024.117941_bib112","doi-asserted-by":"crossref","first-page":"21613","DOI":"10.1002\/jcp.28820","article-title":"Iron and the heart: a paradigm shift from systemic to cardiomyocyte abnormalities","volume":"234","author":"Paterek","year":"2019","journal-title":"J. Cell. Physiol."},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib113","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1080\/17474086.2016.1268047","article-title":"Mitochondria and Iron: current questions","volume":"10","author":"Paul","year":"2017","journal-title":"Expert Rev. Hematol."},{"key":"10.1016\/j.jep.2024.117941_bib114","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154123","article-title":"Recent advances in potential of Fisetin in the management of myocardial ischemia-reperfusion injury-A systematic review","volume":"101","author":"Prem","year":"2022","journal-title":"Phytomedicine"},{"issue":"3","key":"10.1016\/j.jep.2024.117941_bib115","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0122852","article-title":"Secoisolariciresinol diglucoside abrogates oxidative stress-induced damage in cardiac iron overload condition","volume":"10","author":"Puukila","year":"2015","journal-title":"PLoS One"},{"issue":"21","key":"10.1016\/j.jep.2024.117941_bib116","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21217889","article-title":"The molecular mechanisms of iron metabolism and its role in cardiac dysfunction and cardioprotection","volume":"21","author":"Ravingerov\u00e1","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"24","key":"10.1016\/j.jep.2024.117941_bib117","doi-asserted-by":"crossref","first-page":"12671","DOI":"10.1039\/D1FO02913D","article-title":"Sesamin attenuates PM(2.5)-induced cardiovascular injury by inhibiting ferroptosis in rats","volume":"12","author":"Ren","year":"2021","journal-title":"Food Funct."},{"issue":"3","key":"10.1016\/j.jep.2024.117941_bib118","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1007\/s12011-020-02227-3","article-title":"Caffeic acid protects against iron-induced cardiotoxicity by suppressing angiotensin-converting enzyme activity and modulating lipid spectrum, gluconeogenesis and nucleotide hydrolyzing enzyme activities","volume":"199","author":"Salau","year":"2021","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.jep.2024.117941_bib119","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/8880141","article-title":"The protective effect of cyanidin-3-glucoside on myocardial ischemia-reperfusion injury through ferroptosis","volume":"2021","author":"Shan","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.jep.2024.117941_bib120","article-title":"Geniposide possesses the protective effect on myocardial injury by inhibiting oxidative stress and ferroptosis via activation of the grsf1\/GPx4 Axis","volume":"13","author":"Shen","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2024.117941_bib121","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.3389\/fphys.2018.01615","article-title":"Cellular electrophysiology of iron-overloaded cardiomyocytes","volume":"9","author":"Siri-Angkul","year":"2018","journal-title":"Front. Physiol."},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib122","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1080\/13880209.2022.2043392","article-title":"Banxia-Houpu decoction diminishes iron toxicity damage in heart induced by chronic intermittent hypoxia","volume":"60","author":"Song","year":"2022","journal-title":"Pharm. Biol."},{"issue":"2","key":"10.1016\/j.jep.2024.117941_bib123","first-page":"516","article-title":"Ruscogenin induces ferroptosis in pancreatic cancer cells","volume":"43","author":"Song","year":"2020","journal-title":"Oncol. Rep."},{"issue":"5","key":"10.1016\/j.jep.2024.117941_bib124","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1161\/01.ATV.0000124892.90999.cb","article-title":"Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper","volume":"24","author":"Stadler","year":"2004","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib125","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1159\/000489754","article-title":"The influence of hyperlipidemia on endothelial function of FPN1 Tek-Cre Mice and the intervention effect of tetramethylpyrazine","volume":"47","author":"Sun","year":"2018","journal-title":"Cell. Physiol. Biochem."},{"issue":"9","key":"10.1016\/j.jep.2024.117941_bib126","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.132747","article-title":"Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity","volume":"5","author":"Tadokoro","year":"2020","journal-title":"JCI Insight"},{"issue":"6","key":"10.1016\/j.jep.2024.117941_bib127","doi-asserted-by":"crossref","first-page":"8122","DOI":"10.1002\/jcp.27597","article-title":"Mitochondrial quality control in cardiac cells: mechanisms and role in cardiac cell injury and disease","volume":"234","author":"Tahrir","year":"2019","journal-title":"J. Cell. Physiol."},{"issue":"6","key":"10.1016\/j.jep.2024.117941_bib128","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.jnutbio.2014.02.009","article-title":"Quercetin prevents ethanol-induced iron overload by regulating hepcidin through the BMP6\/SMAD4 signaling pathway","volume":"25","author":"Tang","year":"2014","journal-title":"J. Nutr. Biochem."},{"issue":"21","key":"10.1016\/j.jep.2024.117941_bib129","doi-asserted-by":"crossref","first-page":"12223","DOI":"10.1021\/ic400484n","article-title":"Ferritin: the protein nanocage and iron biomineral in health and in disease","volume":"52","author":"Theil","year":"2013","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.jep.2024.117941_bib130","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnutbio.2021.108921","article-title":"Dietary intake of cyanidin-3-glucoside induces a long-lasting cardioprotection from ischemia\/reperfusion injury by altering the microbiota","volume":"101","author":"Trinei","year":"2022","journal-title":"J. Nutr. Biochem."},{"issue":"4","key":"10.1016\/j.jep.2024.117941_bib131","doi-asserted-by":"crossref","first-page":"372","DOI":"10.4103\/0022-3859.143958","article-title":"Cardiac pathology in chronic alcoholics: a preliminary study","volume":"60","author":"Vaideeswar","year":"2014","journal-title":"J. Postgrad. Med."},{"issue":"28","key":"10.1016\/j.jep.2024.117941_bib132","doi-asserted-by":"crossref","first-page":"2681","DOI":"10.1093\/eurheartj\/ehz112","article-title":"Atherosclerosis is aggravated by iron overload and ameliorated by dietary and pharmacological iron restriction","volume":"41","author":"Vinchi","year":"2020","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.jep.2024.117941_bib133","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jep.2017.04.027","article-title":"Danshen injection prevents heart failure by attenuating post-infarct remodeling","volume":"205","author":"Wang","year":"2017","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117941_bib134","article-title":"Liquiritin reduces ferroptosis in doxorubicin-induced cardiotoxicity through targeting SLC7A11\/GPX4 pathway","author":"Wang","year":"2023","journal-title":"Naunyn-Schmiedeberg\u2019s Arch. Pharmacol."},{"issue":"2","key":"10.1016\/j.jep.2024.117941_bib135","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.apsb.2021.10.005","article-title":"Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK\/NRF2 pathways","volume":"12","author":"Wang","year":"2022","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.jep.2024.117941_bib136","article-title":"Role of flavonoids in the treatment of iron overload","volume":"9","author":"Wang","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib137","doi-asserted-by":"crossref","first-page":"E21","DOI":"10.1152\/ajpendo.00227.2021","article-title":"Resveratrol mediates the miR-149\/HMGB1 axis and regulates the ferroptosis pathway to protect myocardium in endotoxemia mice","volume":"323","author":"Wang","year":"2022","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"9","key":"10.1016\/j.jep.2024.117941_bib138","doi-asserted-by":"crossref","first-page":"3951","DOI":"10.1002\/ptr.7854","article-title":"Icariin alleviates ferroptosis-related atherosclerosis by promoting autophagy in xo-LDL-induced vascular endothelial cell injury and atherosclerotic mice","volume":"37","author":"Wang","year":"2023","journal-title":"Phytother Res."},{"issue":"4","key":"10.1016\/j.jep.2024.117941_bib139","doi-asserted-by":"crossref","DOI":"10.1098\/rsob.200367","article-title":"Ferroptosis in myocardial infarction: not a marker but a maker","volume":"11","author":"Wang","year":"2021","journal-title":"Open Biol"},{"key":"10.1016\/j.jep.2024.117941_bib140","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.112367","article-title":"Tongxinluo prevents chronic obstructive pulmonary disease complicated with atherosclerosis by inhibiting ferroptosis and protecting against pulmonary microvascular barrier dysfunction","volume":"145","author":"Wang","year":"2022","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2024.117941_bib141","doi-asserted-by":"crossref","first-page":"308","DOI":"10.3389\/fnagi.2016.00308","article-title":"The protective role of mitochondrial ferritin on erastin-induced ferroptosis","volume":"8","author":"Wang","year":"2016","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.jep.2024.117941_bib142","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/3159717","article-title":"Curcumin attenuates ferroptosis-induced myocardial injury in diabetic cardiomyopathy through the Nrf2 pathway","volume":"2022","author":"Wei","year":"2022","journal-title":"Cardiovasc. Ther."},{"key":"10.1016\/j.jep.2024.117941_bib143","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/978-3-319-18144-8_16","article-title":"The pharmacological effects of S-Propargyl-Cysteine, a novel endogenous H2S-producing compound","volume":"230","author":"Wen","year":"2015","journal-title":"Handb. Exp. Pharmacol."},{"issue":"13","key":"10.1016\/j.jep.2024.117941_bib144","doi-asserted-by":"crossref","first-page":"5546","DOI":"10.1074\/jbc.M117.777201","article-title":"M\u00f6ssbauer Spectra of mouse hearts reveal Age-dependent changes in mitochondrial and ferritin iron levels","volume":"292","author":"Wofford","year":"2017","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jep.2024.117941_bib145","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116282","article-title":"QiShenYiQi dripping pill alleviates myocardial ischemia-induced ferroptosis via improving mitochondrial dynamical homeostasis and biogenesis","volume":"308","author":"Wu","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.117941_bib146","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/3027514","article-title":"6-Gingerol alleviates ferroptosis and inflammation of diabetic cardiomyopathy via the Nrf2\/HO-1 pathway","volume":"2022","author":"Wu","year":"2022","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.jep.2024.117941_bib147","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116289","article-title":"DiDang decoction improves mitochondrial function and lipid metabolism via the HIF-1 signaling pathway to treat atherosclerosis and hyperlipidemia","volume":"308","author":"Wu","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"3","key":"10.1016\/j.jep.2024.117941_bib148","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/cdd.2015.158","article-title":"Ferroptosis: process and function","volume":"23","author":"Xie","year":"2016","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.jep.2024.117941_bib149","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.redox.2017.12.016","article-title":"Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt\/GSK-3\u00df\/Fyn pathway","volume":"15","author":"Xin","year":"2018","journal-title":"Redox Biol."},{"key":"10.1016\/j.jep.2024.117941_bib150","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.pharmthera.2018.11.003","article-title":"Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics","volume":"196","author":"Xu","year":"2019","journal-title":"Pharmacol. Ther."},{"issue":"2","key":"10.1016\/j.jep.2024.117941_bib151","doi-asserted-by":"crossref","first-page":"10924","DOI":"10.1080\/21655979.2021.1995994","article-title":"Naringenin alleviates myocardial ischemia\/reperfusion injury by regulating the nuclear factor-erythroid factor 2-related factor 2 (Nrf2)\/System xc-\/glutathione peroxidase 4 (GPX4) axis to inhibit ferroptosis","volume":"12","author":"Xu","year":"2021","journal-title":"Bioengineered"},{"issue":"9","key":"10.1016\/j.jep.2024.117941_bib152","first-page":"10315","article-title":"Fraxetin attenuates ferroptosis in myocardial infarction via AKT\/Nrf2\/HO-1 signaling","volume":"13","author":"Xu","year":"2021","journal-title":"Am J Transl Res"},{"key":"10.1016\/j.jep.2024.117941_bib153","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.envres.2019.01.040","article-title":"Smog and risk of overall and type-specific cardiovascular diseases: a pooled analysis of 53 cohort studies with 21.09 million participants","volume":"172","author":"Yang","year":"2019","journal-title":"Environ. Res."},{"issue":"3","key":"10.1016\/j.jep.2024.117941_bib154","doi-asserted-by":"crossref","first-page":"310","DOI":"10.4103\/tcmj.tcmj_236_21","article-title":"Berberine protects cardiac cells against ferroptosis","volume":"34","author":"Yang","year":"2022","journal-title":"Tzu Chi Med. J."},{"key":"10.1016\/j.jep.2024.117941_bib155","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.2147\/DDDT.S409232","article-title":"Galangin attenuates myocardial ischemic reperfusion-induced ferroptosis by targeting Nrf2\/Gpx4 signaling pathway","volume":"17","author":"Yang","year":"2023","journal-title":"Drug Des. Dev. Ther."},{"issue":"10","key":"10.1016\/j.jep.2024.117941_bib156","first-page":"2705","article-title":"[Effect of Gegen Qinlian Decoction on cardiac diastolic function of diabetic mice with damp-heat syndrome]","volume":"47","author":"Yu","year":"2022","journal-title":"Zhongguo Zhongyao Zazhi"},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib157","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1038\/s41420-021-00579-w","article-title":"Ferroptosis: a cell death connecting oxidative stress, inflammation and cardiovascular diseases","volume":"7","author":"Yu","year":"2021","journal-title":"Cell Death Dis."},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib158","doi-asserted-by":"crossref","DOI":"10.1080\/08941939.2022.2157521","article-title":"Resveratrol attenuates sepsis-induced cardiomyopathy in rats through anti-ferroptosis via the Sirt1\/Nrf2 pathway","volume":"36","author":"Zeng","year":"2023","journal-title":"J. Invest. Surg."},{"key":"10.1016\/j.jep.2024.117941_bib159","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.112642","article-title":"Icariin and its metabolites as potential protective phytochemicals against cardiovascular disease: from effects to molecular mechanisms","volume":"147","author":"Zeng","year":"2022","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2024.117941_bib160","doi-asserted-by":"crossref","first-page":"124","DOI":"10.3389\/fphar.2014.00124","article-title":"The physiological functions of iron regulatory proteins in iron homeostasis - an update","volume":"5","author":"Zhang","year":"2014","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2024.117941_bib161","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/9800794","article-title":"Hepcidin promoted ferroptosis through iron metabolism which is associated with DMT1 signaling activation in early brain injury following subarachnoid hemorrhage","volume":"2021","author":"Zhang","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"7","key":"10.1016\/j.jep.2024.117941_bib162","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1016\/j.bbadis.2018.08.030","article-title":"Role of iron metabolism in heart failure: from iron deficiency to iron overload","volume":"1865","author":"Zhang","year":"2019","journal-title":"Biochim. Biophys. Acta, Mol. Basis Dis."},{"key":"10.1016\/j.jep.2024.117941_bib163","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115852","article-title":"Qing-Xin-Jie-Yu Granule inhibits ferroptosis and stabilizes atherosclerotic plaques by regulating the GPX4\/xCT signaling pathway","volume":"301","author":"Zhang","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"9","key":"10.1016\/j.jep.2024.117941_bib164","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1055\/s-0032-1328588","article-title":"Salvia miltiorrhiza (Danshen) injection ameliorates iron overload-induced cardiac damage in mice","volume":"79","author":"Zhang","year":"2013","journal-title":"Planta Med."},{"issue":"1","key":"10.1016\/j.jep.2024.117941_bib165","first-page":"501","article-title":"Effect of tetramethylpyrazine and hyperlipidemia on hepcidin homeostasis in mice","volume":"43","author":"Zhang","year":"2019","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.jep.2024.117941_bib166","article-title":"Resveratrol inhibits ferroptosis and decelerates heart failure progression via Sirt1\/p53 pathway activation","author":"Zhang","year":"2023","journal-title":"J. Cell Mol. Med."},{"issue":"4","key":"10.1016\/j.jep.2024.117941_bib167","article-title":"Continuing treatment with Salvia miltiorrhiza injection attenuates myocardial fibrosis in chronic iron-overloaded mice","volume":"10","author":"Zhang","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2024.117941_bib168","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2020.107698","article-title":"Current state and future perspective of cardiovascular medicines derived from natural products","volume":"216","author":"Zhao","year":"2020","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.jep.2024.117941_bib169","doi-asserted-by":"crossref","first-page":"472","DOI":"10.3389\/fphar.2018.00472","article-title":"Curcumin, A polyphenolic curcuminoid with its protective effects and molecular mechanisms in diabetes and diabetic cardiomyopathy","volume":"9","author":"Zheng","year":"2018","journal-title":"Front. Pharmacol."},{"issue":"8","key":"10.1016\/j.jep.2024.117941_bib170","first-page":"3617","article-title":"Puerarin protects against sepsis-induced myocardial injury through AMPK-mediated ferroptosis signaling","volume":"14","author":"Zhou","year":"2022","journal-title":"Aging (Albany N. Y.)"},{"key":"10.1016\/j.jep.2024.117941_bib171","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/4925682","article-title":"Diverse pharmacological activities and potential medicinal benefits of geniposide","volume":"2019","author":"Zhou","year":"2019","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"10.1016\/j.jep.2024.117941_bib172","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s13020-018-0206-9","article-title":"The antityrosinase and antioxidant activities of flavonoids dominated by the number and location of phenolic hydroxyl groups","volume":"13","author":"Zuo","year":"2018","journal-title":"Chin. Med."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037887412400240X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037887412400240X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T17:50:13Z","timestamp":1759945813000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S037887412400240X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":172,"alternative-id":["S037887412400240X"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2024.117941","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Herbal medicines provide regulation against iron overload in cardiovascular diseases: Informing future applications","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2024.117941","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"117941"}}