{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T09:21:38Z","timestamp":1778664098850,"version":"3.51.4"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.jep.2024.118327","type":"journal-article","created":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T15:29:37Z","timestamp":1715614177000},"page":"118327","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Anti-MRSA mechanism of spirostane saponin in Rohdea pachynema F.T.Wang & tang"],"prefix":"10.1016","volume":"331","author":[{"given":"Yang-Zhu","family":"Shi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhao-Jie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nian","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Yu","family":"Bai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue-Ming","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9916-0415","authenticated-orcid":false,"given":"Tie","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei-Zheng","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ma-Long","family":"Qin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Dong","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2024.118327_bib1","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.2147\/IDR.S173867","article-title":"Antibiotic resistance: a rundown of a global crisis","volume":"11","author":"Aslam","year":"2018","journal-title":"Infect. Drug Resist."},{"issue":"4","key":"10.1016\/j.jep.2024.118327_bib2","article-title":"Antimicrobial resistance in methicillin-resistant staphylococcus aureus","volume":"30","author":"Bandar","year":"2023","journal-title":"Saudi J. Biol. Sci."},{"key":"10.1016\/j.jep.2024.118327_bib3","article-title":"Structure-dependent activity of plant natural products against methicillin-resistant Staphylococcus aureus","volume":"14","author":"Calisto","year":"2023","journal-title":"Front. Microbiol."},{"issue":"3","key":"10.1016\/j.jep.2024.118327_bib4","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1002\/cbdv.200900198","article-title":"A new long-chain alkene and antituberculosis constituents from the leaves of Pourthiaea lucida","volume":"7","author":"Chen","year":"2010","journal-title":"Chem. Biodivers."},{"key":"10.1016\/j.jep.2024.118327_bib5","first-page":"44","article-title":"Pharmacognosy study on Xin-Bu-Gan of national medicine","volume":"7","author":"Chen","year":"1997","journal-title":"Chinese Natl Folklore Med."},{"issue":"12","key":"10.1016\/j.jep.2024.118327_bib6","first-page":"860","article-title":"Overview of research on the genus Tupistra","volume":"15","author":"Cheng","year":"2004","journal-title":"LiShiZhen Med and Mater Med Res"},{"issue":"1","key":"10.1016\/j.jep.2024.118327_bib7","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1080\/21505594.2021.1878688","article-title":"Pathogenicity and virulence of Staphylococcus aureus","volume":"12","author":"Cheung","year":"2021","journal-title":"Virulence"},{"issue":"10","key":"10.1016\/j.jep.2024.118327_bib8","doi-asserted-by":"crossref","first-page":"522","DOI":"10.3390\/md18100522","article-title":"Antibacterial activity of chromomycins from a marine-derived Streptomyces microflavus","volume":"18","author":"Cho","year":"2020","journal-title":"Mar. Drugs"},{"issue":"8","key":"10.1016\/j.jep.2024.118327_bib9","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1016\/S0031-9422(97)00197-0","article-title":"Phenylpropanoids from leaves of Juniperus phoenicea","volume":"45","author":"Comte","year":"1997","journal-title":"Phytochemistry"},{"issue":"8","key":"10.1016\/j.jep.2024.118327_bib10","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1039\/C9MD00044E","article-title":"Methicillin-resistant Staphylococcus aureus (MRSA): antibiotic-resistance and the biofilm phenotype","volume":"10","author":"Craft","year":"2019","journal-title":"MedChemComm"},{"key":"10.1016\/j.jep.2024.118327_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.jare.2023.11.005","article-title":"Discovery of new quaternized norharmane dimers as potential anti-MRSA agents","author":"Dai","year":"2023","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.jep.2024.118327_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmc.2022.117135","article-title":"Efficient delivery of VEGFA mRNA for promoting wound healing via ionizable lipid nanoparticles","volume":"78","author":"Dong","year":"2023","journal-title":"Bioorg. Med. Chem."},{"issue":"5","key":"10.1016\/j.jep.2024.118327_bib13","doi-asserted-by":"crossref","first-page":"617","DOI":"10.3390\/ijms17050617","article-title":"New is old, and old is new: recent advances in antibiotic-based, antibiotic-free and ethnomedical treatments against methicillin-resistant Staphylococcus aureus wound infections","volume":"17","author":"Dou","year":"2016","journal-title":"Int. J. Mol. Sci."},{"issue":"15","key":"10.1016\/j.jep.2024.118327_bib14","doi-asserted-by":"crossref","first-page":"7156","DOI":"10.1039\/D2FO03212K","article-title":"Vitis vinifera leaf extract liposomal Carbopol gel preparation's potential wound healing and antibacterial benefits: in vivo, phytochemical, and computational investigation","volume":"14","author":"Elmaidomy","year":"2023","journal-title":"Food Funct."},{"key":"10.1016\/j.jep.2024.118327_bib15","article-title":"Prenylated phenolics from Morus alba against MRSA infections as a strategy for wound healing","volume":"13","author":"Gabriela","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2024.118327_bib16","series-title":"Chinese Medicinal Composition for Treatment of Lung Abscess and Preparation Method Thereof","author":"Gao","year":"2014"},{"issue":"6","key":"10.1016\/j.jep.2024.118327_bib17","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1021\/np0305019","article-title":"Antimycotic spirostanol saponins from Solanum hispidum leaves and their Structure\u2212Activity relationships","volume":"67","author":"Gonzalez","year":"2004","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.jep.2024.118327_bib18","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3389\/fcimb.2020.00107","article-title":"Prevalence and therapies of antibiotic-resistance in Staphylococcus aureus","volume":"10","author":"Guo","year":"2020","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"3","key":"10.1016\/j.jep.2024.118327_bib19","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1093\/femsre\/fux010","article-title":"Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria","volume":"41","author":"Hall","year":"2017","journal-title":"FEMS Microbiol. Rev."},{"issue":"9","key":"10.1016\/j.jep.2024.118327_bib20","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1007\/s11745-011-3592-7","article-title":"Efficient and specific conversion of 9-lipoxygenase hydroperoxides in the beetroot. Formation of pinellic acid","volume":"46","author":"Hamberg","year":"2011","journal-title":"Lipids"},{"issue":"10","key":"10.1016\/j.jep.2024.118327_bib21","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/s41580-018-0046-6","article-title":"Sphingolipids and their metabolism in physiology and disease","volume":"19","author":"Hannun","year":"2018","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"4","key":"10.1016\/j.jep.2024.118327_bib22","first-page":"78","article-title":"Separation and identification of chemical constituents of Alisma plantago-aquatica","volume":"22","author":"Hong","year":"2008","journal-title":"J Chongqing Univ Sci Technol."},{"key":"10.1016\/j.jep.2024.118327_bib23","doi-asserted-by":"crossref","first-page":"3271","DOI":"10.2147\/IDR.S412308","article-title":"Progress in the prevalence, classification and drug resistance mechanisms of methicillin-resistant Staphylococcus aureus","volume":"16","author":"Hou","year":"2023","journal-title":"Infect. Drug Resist."},{"issue":"7","key":"10.1016\/j.jep.2024.118327_bib24","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1002\/ptr.2446","article-title":"Isolation of linoleic and alpha-linolenic acids as COX-1 and -2 inhibitors in rose hip","volume":"22","author":"J\u00e4ger","year":"2008","journal-title":"Phytother Res."},{"key":"10.1016\/j.jep.2024.118327_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2022.132932","article-title":"Screening of specific quantitative peptides of beef by LC\u2013MS\/MS coupled with OPLS-DA","volume":"387","author":"Kang","year":"2022","journal-title":"Food Chem."},{"key":"10.1016\/j.jep.2024.118327_bib26","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1007\/s11255-023-03779-8","article-title":"Metabolic implications of amino acid metabolites in chronic kidney disease progression: a metabolomics analysis using OPLS-DA and MBRole2.0 database","volume":"56","author":"Kang","year":"2023","journal-title":"Int. Urol. Nephrol."},{"issue":"1","key":"10.1016\/j.jep.2024.118327_bib27","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1023\/A:1024136814618","article-title":"Polyhydroxysteroids and thymidine from the sea pen Pavonaria finmarchica","volume":"9","author":"Kapustina","year":"2003","journal-title":"Chem. Nat. Compd."},{"issue":"8","key":"10.1016\/j.jep.2024.118327_bib28","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1007\/BF02968244","article-title":"Chemical constituents of the root of Dystaenia takeshimana and their anti-inflammatory activity","volume":"29","author":"Kim","year":"2006","journal-title":"Arch Pharm Res"},{"issue":"3","key":"10.1016\/j.jep.2024.118327_bib29","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1007\/PL00000710","article-title":"Inhibition of xanthine oxidase by liquiritigenin and isoliquiritigenin isolated from Sinofranchetia chinensis","volume":"57","author":"Kong","year":"2000","journal-title":"Cell. Mol. Life Sci."},{"issue":"10","key":"10.1016\/j.jep.2024.118327_bib30","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1016\/j.addr.2005.04.004","article-title":"Bacterial resistance to antibiotics: active efflux and reduced uptake","volume":"57","author":"Kumar","year":"2005","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jep.2024.118327_bib31","series-title":"Annals of Chinese Medicine in Yunnan (Volume \u2160)","author":"Li","year":"1990"},{"key":"10.1016\/j.jep.2024.118327_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154073","article-title":"Phytochemicals with activity against methicillin-resistant Staphylococcus aureus","volume":"100","author":"Liang","year":"2022","journal-title":"Phytomedicine"},{"issue":"Part_A","key":"10.1016\/j.jep.2024.118327_bib33","article-title":"Curcusinol from the fruit of Carex baccans with antibacterial activity against multidrug-resistant strains","volume":"318","author":"Liu","year":"2024","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.jep.2024.118327_bib34","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/jb\/mvab043","article-title":"D-Amino acid metabolism in bacteria","volume":"170","author":"Miyamoto","year":"2021","journal-title":"J. Biochem."},{"key":"10.1016\/j.jep.2024.118327_bib35","doi-asserted-by":"crossref","first-page":"2675","DOI":"10.3390\/molecules17032675","article-title":"Bioactive phenolic amides from Celtis africana","volume":"17","author":"Mohammad","year":"2012","journal-title":"Molecules"},{"issue":"5","key":"10.1016\/j.jep.2024.118327_bib36","doi-asserted-by":"crossref","first-page":"606","DOI":"10.3390\/antibiotics11050606","article-title":"Recent developments in methicillin-resistant Staphylococcus aureus (MRSA) treatment: a review","volume":"11","author":"Nandhini","year":"2022","journal-title":"Antibiotics"},{"issue":"3","key":"10.1016\/j.jep.2024.118327_bib37","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1515\/znb-2010-0327","article-title":"Syntheses and palladium, platinum, and borane adducts of symmetrical trialkylphosphines with three terminal vinyl groups, P((CH2)mCH=CH2)3","volume":"65","author":"Nawara-Hultzsch","year":"2010","journal-title":"Z. Naturforsch. B Chem. Sci."},{"issue":"6","key":"10.1016\/j.jep.2024.118327_bib38","first-page":"879","article-title":"Studies on steroids from the rhizomes of tupistra chinensis","volume":"26","author":"Ning","year":"2014","journal-title":"Nat. Prod. Res."},{"key":"10.1016\/j.jep.2024.118327_bib39","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.676534","article-title":"A strong synergy between the thiopeptide bacteriocin micrococcin P1 and rifampicin against MRSA in a murine skin infection model","volume":"12","author":"Ovchinnikov","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jep.2024.118327_bib40","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1327069","article-title":"A growing battlefield in the war against biofilm-induced antimicrobial resistance: insights from reviews on antibiotic resistance","volume":"13","author":"Pai","year":"2023","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"2","key":"10.1016\/j.jep.2024.118327_bib41","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1021\/np0203382","article-title":"New flavans, spirostanol sapogenins, and a pregnane genin from Tupistra chinensis and their cytotoxicity","volume":"66","author":"Pan","year":"2003","journal-title":"J. Nat. Prod."},{"issue":"3","key":"10.1016\/j.jep.2024.118327_bib42","first-page":"4","article-title":"Research progress on chemical constituents and activity of Tupistra in Liliaceae","volume":"11","author":"Qiao","year":"2009","journal-title":"J Hubei Univ Trad Chinese Med"},{"issue":"6","key":"10.1016\/j.jep.2024.118327_bib43","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1007\/BF02977632","article-title":"In vivo and in vitro anti-inflammatory activities of alpha-linolenic acid isolated from Actinidia polygama fruits","volume":"30","author":"Ren","year":"2007","journal-title":"Arch Pharm Res"},{"key":"10.1016\/j.jep.2024.118327_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.matdes.2023.111890","article-title":"Au@MOFs used as peroxidase-like catalytic nanozyme for bacterial infected wound healing through bacterial membranes disruption and protein leakage promotion","volume":"229","author":"Ren","year":"2023","journal-title":"Mater. Des."},{"issue":"11","key":"10.1016\/j.jep.2024.118327_bib45","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.3390\/ph15111382","article-title":"Alginate\u2013chitosan hydrogel formulations sustain baculovirus delivery and VEGFA expression which promotes angiogenesis for wound dressing applications","volume":"15","author":"Schaly","year":"2022","journal-title":"Pharmaceuticals"},{"issue":"15","key":"10.1016\/j.jep.2024.118327_bib46","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202100749","article-title":"Plant natural flavonoids against multidrug resistant pathogens","volume":"8","author":"Song","year":"2021","journal-title":"Adv. Sci."},{"key":"10.1016\/j.jep.2024.118327_bib47","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1146\/annurev-micro-102215-095630","article-title":"Bacterial membranes: structure, domains, and function","volume":"71","author":"Strahl","year":"2017","journal-title":"Annu. Rev. Microbiol."},{"issue":"27","key":"10.1016\/j.jep.2024.118327_bib48","doi-asserted-by":"crossref","first-page":"12281","DOI":"10.1073\/pnas.1005485107","article-title":"Membrane potential is important for bacterial cell division","volume":"107","author":"Strahl","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"19","key":"10.1016\/j.jep.2024.118327_bib49","doi-asserted-by":"crossref","first-page":"9552","DOI":"10.1073\/pnas.1901788116","article-title":"Electrically induced bacterial membrane potential dynamics correspond to cellular proliferation capacity","volume":"116","author":"Stratford","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.jep.2024.118327_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2023.138193","article-title":"The adsorption of 2-amino-1-methyl-6-phenyl-imidazolium [4, 5-B] pyridine (PhIP) by lactic acid bacteria 37X-15 and its peptidoglycan","volume":"440","author":"Sun","year":"2024","journal-title":"Food Chem."},{"issue":"5","key":"10.1016\/j.jep.2024.118327_bib51","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1248\/yakushi1947.99.5_528","article-title":"Studies on the constituents of \\sSenshokushichikon\\\". II. Isolation ans Structurae Elucidation os Spirostand Derivatives","volume":"99","author":"Takahira","year":"1979","journal-title":"Yakugaku Zasshi"},{"issue":"1","key":"10.1016\/j.jep.2024.118327_bib52","article-title":"Genus tupistra: a comprehensive review of phytochemistry and pharmacological activity","volume":"17","author":"Thuy Linh","year":"2022","journal-title":"Nat. Prod. Commun."},{"issue":"18","key":"10.1016\/j.jep.2024.118327_bib53","doi-asserted-by":"crossref","first-page":"6342","DOI":"10.1039\/D3BM01039B","article-title":"Prussian blue nano-enzyme-assisted photodynamic therapy effectively eradicates MRSA infection in diabetic mouse skin wounds","volume":"11","author":"Tong","year":"2023","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.jep.2024.118327_bib54","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.ijbiomac.2020.04.231","article-title":"Proteomic profiling unveils citral modulating expression of IsaA, CodY and SaeS to inhibit biofilm and virulence in Methicillin-resistant Staphylococcus aureus","volume":"158","author":"Valliammai","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"issue":"6","key":"10.1016\/j.jep.2024.118327_bib55","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1111\/j.1472-765X.2006.02018.x","article-title":"Methicillin-resistant staphylococcal colonization in clinically normal dogs and horses in the community","volume":"43","author":"Vengust","year":"2006","journal-title":"Lett. Appl. Microbiol."},{"key":"10.1016\/j.jep.2024.118327_bib56","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1159798","article-title":"Revisiting ESKAPE Pathogens: virulence, resistance, and combating strategies focusing on quorum sensing","volume":"13","author":"Venkateswaran","year":"2023","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"23","key":"10.1016\/j.jep.2024.118327_bib57","doi-asserted-by":"crossref","first-page":"5502","DOI":"10.1080\/14786419.2020.1788022","article-title":"Cytotoxic activity of steroidal glycosides from the aerial parts of Solanum torvum collected in Thua Thien Hue, Vietnam","volume":"35","author":"Viet Cuong","year":"2020","journal-title":"Nat. Prod. Res."},{"issue":"17","key":"10.1016\/j.jep.2024.118327_bib58","doi-asserted-by":"crossref","first-page":"4817","DOI":"10.1016\/S0040-4020(01)82062-7","article-title":"Photochemistry of latifolin and some related compounds","volume":"42","author":"Walia","year":"1986","journal-title":"Tetrahedron"},{"key":"10.1016\/j.jep.2024.118327_bib59","first-page":"44","article-title":"Comparison of traditional application of national medicine Xin-Bu-Gan","volume":"7","author":"Wan","year":"2007","journal-title":"Chinese J Ethnic Med."},{"key":"10.1016\/j.jep.2024.118327_bib60","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1007\/s13659-023-00397-w","article-title":"Antifungal alkaloids from Mahonia fortunei against pathogens of postharvest fruit","volume":"13","author":"Wang","year":"2023","journal-title":"Nat Prod Bioprospect"},{"key":"10.1016\/j.jep.2024.118327_bib61","first-page":"341","article-title":"A steroidal sapogenin from tupistar wattii","volume":"3","author":"Wang","year":"1995","journal-title":"Acta Bot. Yunnanica"},{"key":"10.1016\/j.jep.2024.118327_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.fbio.2021.101206","article-title":"Comparison of chemical constituents in diverse zanthoxylum herbs, and evaluation of their relative antibacterial and nematicidal activity","volume":"42","author":"Wang","year":"2021","journal-title":"Food Biosci."},{"key":"10.1016\/j.jep.2024.118327_bib63","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.113119","article-title":"Bioguided isolation, identification and activity evaluation of antifungal compounds from Acorus tatarinowii Schott","volume":"261","author":"Wang","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.118327_bib64","series-title":"Global Action Plan on Antimicrobial Resistance","year":"2015"},{"key":"10.1016\/j.jep.2024.118327_bib65","series-title":"Global Priority List of Antibiotic Resistant Bacteria to Guide Research, Discovery, and Development of New Antibiotics","year":"2017"},{"key":"10.1016\/j.jep.2024.118327_bib66","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116177","article-title":"Antibacterial and antibiofilm efficacy of the preferred fractions and compounds from Euphorbia humifusa (herba euphorbiae humifusae) against Staphylococcus aureus","volume":"306","author":"Wu","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"11","key":"10.1016\/j.jep.2024.118327_bib67","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1021\/acsinfecdis.2c00365","article-title":"Discovery of new anti-MRSA agents based on phenoxyethanol and its mechanism","volume":"8","author":"Xie","year":"2022","journal-title":"ACS Infect. Dis."},{"issue":"5","key":"10.1016\/j.jep.2024.118327_bib68","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/S0031-9422(96)00396-2","article-title":"Steroidal glycosides from Solanum torvum","volume":"43","author":"Yahara","year":"1996","journal-title":"Phytochemistry"},{"issue":"24","key":"10.1016\/j.jep.2024.118327_bib69","doi-asserted-by":"crossref","first-page":"16879","DOI":"10.1021\/acs.jmedchem.2c01674","article-title":"Membrane-targeting neolignan-antimicrobial peptide mimic conjugates to combat methicillin-resistant Staphylococcus aureus (MRSA) infections","volume":"65","author":"Yang","year":"2022","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jep.2024.118327_bib70","volume":"1268367 A","author":"Yang","year":"2013"},{"issue":"1","key":"10.1016\/j.jep.2024.118327_bib71","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1080\/13880209.2019.1674342","article-title":"The antibacterial mechanism of oridonin against methicillin-resistant Staphylococcus aureus (MRSA)","volume":"57","author":"Yuan","year":"2019","journal-title":"Pharm. Biol."},{"issue":"15","key":"10.1016\/j.jep.2024.118327_bib72","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1080\/14786419.2014.1002089","article-title":"A new myrsinol-type diterpene polyester from Euphorbia dracunculoides Lam","volume":"29","author":"Zang","year":"2015","journal-title":"Nat. Prod. Res."},{"issue":"7","key":"10.1016\/j.jep.2024.118327_bib73","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1080\/14786419.2019.1644509","article-title":"Three new steroidal components from the roots of reineckia carnea","volume":"35","author":"Zheng","year":"2021","journal-title":"Nat. Prod. Res."},{"key":"10.1016\/j.jep.2024.118327_bib74","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114542","article-title":"Bioguided isolation, identification and bioactivity evaluation of anti-MRSA constituents from Morus alba Linn","volume":"281","author":"Zhu","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.118327_bib75","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmc.2023.117544","article-title":"A dual mechanism with H2S inhibition and membrane damage of morusin from Morus alba Linn. against MDR-MRSA","volume":"97","author":"Zhu","year":"2024","journal-title":"Bioorg. Med. Chem."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874124006263?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874124006263?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T14:35:42Z","timestamp":1719326142000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874124006263"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":75,"alternative-id":["S0378874124006263"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2024.118327","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anti-MRSA mechanism of spirostane saponin in Rohdea pachynema F.T.Wang & tang","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2024.118327","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"118327"}}