{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T13:28:18Z","timestamp":1782307698915,"version":"3.54.5"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100022026","name":"Aswan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.jep.2024.118768","type":"journal-article","created":{"date-parts":[[2024,8,31]],"date-time":"2024-08-31T02:52:11Z","timestamp":1725072731000},"page":"118768","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"P1","title":["Evaluation of in-vitro antioxidant activity, acute oral toxicity, and pancreatic and hepatic protective effects of Aloe rubroviolacea flowers extract against CCl4 toxicity in a rat model"],"prefix":"10.1016","volume":"337","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3177-3420","authenticated-orcid":false,"given":"Nesreen M.I.M.","family":"Elkomy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8349-9967","authenticated-orcid":false,"given":"Amina","family":"El-Shaibany","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Al-Mahbashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2198-0549","authenticated-orcid":false,"given":"Ahmed S.","family":"Abdelkhalek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gehad M.","family":"Elnagar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud M.","family":"Elaasser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8567-3970","authenticated-orcid":false,"given":"Ali E.","family":"Raslan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.jep.2024.118768_bib1","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/s11130-022-01007-9","article-title":"Ferocactus herrerae fruits: nutritional significance, phytochemical profiling, and biological potentials","volume":"77","author":"Abdel-Baki","year":"2022","journal-title":"Plant Foods Hum. Nutr."},{"key":"10.1016\/j.jep.2024.118768_bib2","first-page":"1","article-title":"Ethnobotanical knowledge and threat factors for Aloe species in Tanzania","volume":"18","author":"Abihudi","year":"2019","journal-title":"Ethnobot. Res. Appl."},{"key":"10.1016\/j.jep.2024.118768_bib3","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.biopha.2016.09.096","article-title":"Therapeutic effects of Aloe spp. in traditional and modern medicine: a review","volume":"84","author":"Akaberi","year":"2016","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2024.118768_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2019.111973","article-title":"Ethnobotanical survey of medicinal plants in central Abyan governorate, Yemen","volume":"241","author":"Al-Fatimi","year":"2019","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.118768_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.116033","article-title":"Ethnopharmacological survey of endemic plants used in ethnomedicinal knowledge of Soqotra Island","volume":"304","author":"Al-Fatimi","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.118768_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/14786419.2023.2280820","article-title":"GC-MS profiling and evaluation of acute oral toxicity, anti-tumour, antimicrobial and antioxidant activities of Croton socotranus Balf.f. aerial parts: in-vitro, in-vivo and in-silico studies","author":"Al-Hakami","year":"2023","journal-title":"Nat. Prod. Res."},{"issue":"2","key":"10.1016\/j.jep.2024.118768_bib7","first-page":"93","article-title":"Aloe arborescens preparation and liver health","volume":"14","author":"Anwar","year":"2009","journal-title":"Eur. J. Oncol."},{"key":"10.1016\/j.jep.2024.118768_bib8","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.sajb.2021.07.036","article-title":"A review of Aloe species used in traditional medicine in East Africa","volume":"147","author":"Anywar","year":"2022","journal-title":"South Afr. J. Bot."},{"issue":"10","key":"10.1016\/j.jep.2024.118768_bib9","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.3390\/antiox11101912","article-title":"Health benefits and pharmacological properties of stigmasterol","volume":"11","author":"Bakrim","year":"2022","journal-title":"Antioxidants"},{"issue":"6","key":"10.1016\/j.jep.2024.118768_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2020.e04344","article-title":"Ethno-medicinal and bio-cultural importance of aloes from south and east of the Great Rift Valley floristic regions of Ethiopia","volume":"6","author":"Belayneh","year":"2020","journal-title":"Heliyon"},{"issue":"7\u20138","key":"10.1016\/j.jep.2024.118768_bib11","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1515\/znc-2001-7-826","article-title":"Mechanism of carbon tetrachloride-induced hepatotoxicity. Hepatocellular damage by reactive carbon tetrachloride metabolites","volume":"56","author":"Boll","year":"2001","journal-title":"Z. Naturforsch. C Biosci."},{"key":"10.1016\/j.jep.2024.118768_bib12","series-title":"Aloes\u2013The Definitive Guide","author":"Carter","year":"2011"},{"issue":"3","key":"10.1016\/j.jep.2024.118768_bib13","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.jep.2007.01.008","article-title":"Hepatoprotective potential of Aloe barbadensis Mill. against carbon tetrachloride induced hepatotoxicity","volume":"111","author":"Chandan","year":"2007","journal-title":"J. Ethnopharmacol."},{"issue":"5","key":"10.1016\/j.jep.2024.118768_bib14","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/cld.1061","article-title":"Global epidemiology of chronic liver disease","volume":"17","author":"Cheemerla","year":"2021","journal-title":"Clin. Liver Dis."},{"issue":"2","key":"10.1016\/j.jep.2024.118768_bib15","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.jhep.2023.03.017","article-title":"Global burden of liver disease: 2023 update","volume":"79","author":"Devarbhavi","year":"2023","journal-title":"J. Hepatol."},{"key":"10.1016\/j.jep.2024.118768_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116310","article-title":"Evaluation of acute oral toxicity, anti-diabetic and antioxidant effects of Aloe vera flowers extract","volume":"309","author":"Elkomy","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"14","key":"10.1016\/j.jep.2024.118768_bib17","doi-asserted-by":"crossref","first-page":"4145","DOI":"10.3390\/molecules26144145","article-title":"Antioxidant activity and molecular docking study of volatile constituents from different aromatic lamiaceous plants cultivated in Madinah Monawara, Saudi Arabia","volume":"26","author":"Farouk","year":"2021","journal-title":"Molecules"},{"issue":"6","key":"10.1016\/j.jep.2024.118768_bib18","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1177\/0300985813485099","article-title":"Principles for valid histopathologic scoring in research","volume":"50","author":"Gibson-Corley","year":"2013","journal-title":"Vet. Pathol."},{"issue":"5","key":"10.1016\/j.jep.2024.118768_bib19","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.gastha.2022.05.006","article-title":"Silymarin for treating toxic liver disease: international consensus recommendations","volume":"1","author":"Gillessen","year":"2022","journal-title":"Gastro Hep Advances"},{"issue":"1","key":"10.1016\/j.jep.2024.118768_bib20","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.jmb.2010.07.022","article-title":"Structural evidence that peroxiredoxin catalytic power is based on transition-state stabilization","volume":"402","author":"Hall","year":"2010","journal-title":"J. Mol. Biol."},{"issue":"17","key":"10.1016\/j.jep.2024.118768_bib21","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.3748\/wjg.v18.i17.2026","article-title":"Antifibrotic effect of aloe vera in viral infection-induced hepatic periportal fibrosis","volume":"18","author":"Hegazy","year":"2012","journal-title":"World J. Gastroenterol.: WJG"},{"issue":"3","key":"10.1016\/j.jep.2024.118768_bib22","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s00281-009-0155-6","article-title":"Liver architecture, cell function, and disease","volume":"31","author":"Ishibashi","year":"2009","journal-title":"Semin. Immunopathol."},{"issue":"6","key":"10.1016\/j.jep.2024.118768_bib23","doi-asserted-by":"crossref","first-page":"5268","DOI":"10.3390\/molecules16065268","article-title":"Acute oral toxicity of methanolic seed extract of Cassia fistula in mice","volume":"16","author":"Jothy","year":"2011","journal-title":"Molecules"},{"issue":"2","key":"10.1016\/j.jep.2024.118768_bib24","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1002\/jsfa.10650","article-title":"Quantitative determination of aloin, antioxidant activity, and toxicity of Aloe vera leaf gel products from Greece","volume":"101","author":"Kaparakou","year":"2021","journal-title":"J. Sci. Food Agric."},{"issue":"3","key":"10.1016\/j.jep.2024.118768_bib25","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1016\/j.sjbs.2021.10.045","article-title":"Screening of potential cytotoxic activities of some medicinal plants of Saudi Arabia","volume":"29","author":"Khan","year":"2022","journal-title":"Saudi J. Biol. Sci."},{"key":"10.1016\/j.jep.2024.118768_bib26","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.biopha.2016.06.023","article-title":"Hepatoprotective and antioxidant potential of Asphodeline lutea (L.) Rchb. roots extract in experimental models in vitro\/in vivo","volume":"83","author":"Lazarova","year":"2016","journal-title":"Biomed. Pharmacother."},{"issue":"32","key":"10.1016\/j.jep.2024.118768_bib27","doi-asserted-by":"crossref","first-page":"9648","DOI":"10.1021\/bi060692p","article-title":"The crystal structure of NAD (P) H oxidase from Lactobacillus sanfranciscensis: insights into the conversion of O2 into two water molecules by the flavoenzyme","volume":"45","author":"Lountos","year":"2006","journal-title":"Biochemistry"},{"issue":"3","key":"10.1016\/j.jep.2024.118768_bib28","article-title":"Hepatoprotective activity of Aloe vera gel against paracetamol induced hepatotoxicity in albino rats","volume":"2","author":"Madhav","year":"2011","journal-title":"Carbon"},{"key":"10.1016\/j.jep.2024.118768_bib29","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s00217-014-2353-2","article-title":"Flavone C-glycosides from Capsicum annuum L.: relationships between antioxidant activity and lipophilicity","volume":"240","author":"Materska","year":"2015","journal-title":"Eur. Food Res. Technol."},{"issue":"5","key":"10.1016\/j.jep.2024.118768_bib30","doi-asserted-by":"crossref","first-page":"258","DOI":"10.2985\/015.086.0604","article-title":"Two new species of aloe from the kingdom of Saudi arabia","volume":"86","author":"McCoy","year":"2014","journal-title":"Cactus Succulent J."},{"issue":"2","key":"10.1016\/j.jep.2024.118768_bib31","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1002\/jcp.21172","article-title":"Liver regeneration","volume":"213","author":"Michalopoulos","year":"2007","journal-title":"J. Cell. Physiol."},{"issue":"20","key":"10.1016\/j.jep.2024.118768_bib32","first-page":"4242","article-title":"Aloe arborescens aqueous gel extract alters the activities of key hepatic enzymes and blood concentration of triglycerides, glucose and insulin in alloxan-induced diabetic rats","volume":"10","author":"Mogale","year":"2011","journal-title":"Afr. J. Biotechnol."},{"key":"10.1016\/j.jep.2024.118768_bib33","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1590\/S0102-695X2011005000174","article-title":"Constituents and antiproliferative activity of extracts from leaves of Croton macrobothrys","volume":"21","author":"Motta","year":"2011","journal-title":"Rev. Bras. Farmacogn."},{"issue":"3","key":"10.1016\/j.jep.2024.118768_bib34","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/j.1472-8206.1989.tb00449.x","article-title":"Prevention of CCl4\u2010induced liver cirrhosis by silymarin","volume":"3","author":"Mourelle","year":"1989","journal-title":"Fundam. Clin. Pharmacol."},{"issue":"3","key":"10.1016\/j.jep.2024.118768_bib35","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1021\/acs.jnatprod.9b01285","article-title":"Natural products as sources of new drugs over the nearly four decades from 01\/1981 to 09\/2019","volume":"83","author":"Newman","year":"2020","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.jep.2024.118768_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.sciaf.2022.e01132","article-title":"Phytochemical properties and pharmacological activities of the genus Pennisetum: a review","volume":"16","author":"Ojo","year":"2022","journal-title":"Scientific African"},{"key":"10.1016\/j.jep.2024.118768_bib38","series-title":"Cellular and Molecular Mechanisms of Pancreatitis in Atrophy and Regeneration","author":"Reid","year":"2019"},{"issue":"11","key":"10.1016\/j.jep.2024.118768_bib39","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1271\/bbb.120393","article-title":"Aloe vera gel extract attenuates ethanol-induced hepatic lipid accumulation by suppressing the expression of lipogenic genes in mice","volume":"76","author":"Saito","year":"2012","journal-title":"Biosci. Biotechnol. Biochem."},{"issue":"14","key":"10.1016\/j.jep.2024.118768_bib40","doi-asserted-by":"crossref","first-page":"742","DOI":"10.3923\/pjbs.2011.742.746","article-title":"Hepatotherapeutic effect of Aloe vera in alcohol-induced hepatic damage","volume":"14","author":"Saka","year":"2011","journal-title":"Pakistan J. Biol. Sci.: PJBS"},{"issue":"1","key":"10.1016\/j.jep.2024.118768_bib41","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1038\/s41598-020-59218-6","article-title":"Synthesis, bioevaluation, structure-activity relationship and docking studies of natural product inspired (Z)-3-benzylideneisobenzofuran-1 (3H)-ones as highly potent antioxidants and antiplatelet agents","volume":"10","author":"Shyamlal","year":"2020","journal-title":"Sci. Rep."},{"issue":"12","key":"10.1016\/j.jep.2024.118768_bib42","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1002\/ptr.5483","article-title":"A systemic review on aloe arborescens pharmacological profile: biological activities and pilot clinical trials","volume":"29","author":"Singab","year":"2015","journal-title":"Phytother Res."},{"key":"10.1016\/j.jep.2024.118768_bib43","doi-asserted-by":"crossref","first-page":"363","DOI":"10.3389\/fphys.2015.00363","article-title":"Drug-induced liver toxicity and prevention by herbal antioxidants: an overview","volume":"6","author":"Singh","year":"2016","journal-title":"Front. Physiol."},{"issue":"3","key":"10.1016\/j.jep.2024.118768_bib44","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0944-7113(00)80006-9","article-title":"Chemomodulatory action of Aloe vera on the profiles of enzymes associated with carcinogen metabolism and antioxidant status regulation in mice","volume":"7","author":"Singh","year":"2000","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2024.118768_bib45","series-title":"Bancroft's Theory and Practice of Histological Techniques E-Book","author":"Suvarna","year":"2018"},{"issue":"2","key":"10.1016\/j.jep.2024.118768_bib46","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1248\/bpb.35.171","article-title":"The molecular mechanisms of the hepatoprotective effect of gomisin A against oxidative stress and inflammatory response in rats with carbon tetrachloride-induced acute liver injury","volume":"35","author":"Teraoka","year":"2012","journal-title":"Biol. Pharm. Bull."},{"issue":"3","key":"10.1016\/j.jep.2024.118768_bib47","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.foodchem.2004.06.018","article-title":"Concentration-dependence of prooxidant and antioxidant effects of aloin and aloe-emodin on DNA","volume":"91","author":"Tian","year":"2005","journal-title":"Food Chem."},{"issue":"1","key":"10.1016\/j.jep.2024.118768_bib48","first-page":"98","article-title":"Phytochemical screening and extraction: a review","volume":"1","author":"Tiwari","year":"2011","journal-title":"Int. Pharm. Sci."},{"issue":"1","key":"10.1016\/j.jep.2024.118768_bib49","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1748-1716.2009.01970.x","article-title":"AMP\u2010activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives","volume":"196","author":"Viollet","year":"2009","journal-title":"Acta Physiol."},{"issue":"1","key":"10.1016\/j.jep.2024.118768_bib50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/22311866.2018.1426495","article-title":"Therapeutic applications of natural products in herbal medicines, biodiscovery programs, and biomedicine","volume":"8","author":"Wangchuk","year":"2018","journal-title":"Journal of Biologically Active Products from Nature"},{"issue":"2","key":"10.1016\/j.jep.2024.118768_bib51","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1080\/713611034","article-title":"Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model","volume":"33","author":"Weber","year":"2003","journal-title":"Crit. Rev. Toxicol."},{"issue":"11","key":"10.1016\/j.jep.2024.118768_bib52","doi-asserted-by":"crossref","first-page":"2655","DOI":"10.3390\/nu11112655","article-title":"Hepatoprotective mechanisms of taxifolin on carbon tetrachloride-induced acute liver injury in mice","volume":"11","author":"Yang","year":"2019","journal-title":"Nutrients"},{"issue":"3","key":"10.1016\/j.jep.2024.118768_bib53","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1021\/jf00039a005","article-title":"Scavenging effect of methanolic extracts of peanut hulls on free-radical and active-oxygen species","volume":"42","author":"Yen","year":"1994","journal-title":"J. Agric. Food Chem."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874124010675?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874124010675?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,10]],"date-time":"2024-11-10T23:28:15Z","timestamp":1731281295000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874124010675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":52,"alternative-id":["S0378874124010675"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2024.118768","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of in-vitro antioxidant activity, acute oral toxicity, and pancreatic and hepatic protective effects of Aloe rubroviolacea flowers extract against CCl4 toxicity in a rat model","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2024.118768","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"118768"}}