{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:08:29Z","timestamp":1791562109357,"version":"4.3.4"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.jep.2024.118925","type":"journal-article","created":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T09:18:34Z","timestamp":1728551914000},"page":"118925","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"P3","title":["Protective effects of phenylethanol glycosides from Cistanche tubulosa against ALD through modulating gut microbiota homeostasis"],"prefix":"10.1016","volume":"337","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9119-1062","authenticated-orcid":false,"given":"Zhaoyao","family":"Qi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jincun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanhui","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongguang","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinxin","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meili","family":"Cong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinxuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9663-0378","authenticated-orcid":false,"given":"Tao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jep.2024.118925_bib1","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s00018-018-2943-4","article-title":"An insight into gut microbiota and its functionalities","volume":"76","author":"Adak","year":"2019","journal-title":"Cell. Mol. Life Sci."},{"issue":"3","key":"10.1016\/j.jep.2024.118925_bib2","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.jhep.2019.10.003","article-title":"The gut-liver axis in liver disease: pathophysiological basis for therapy","volume":"72","author":"Albillos","year":"2020","journal-title":"J. Hepatol."},{"issue":"4","key":"10.1016\/j.jep.2024.118925_bib3","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/s41575-018-0099-1","article-title":"Alcohol, liver disease and the gut microbiota","volume":"16","author":"Bajaj","year":"2019","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"3","key":"10.1016\/j.jep.2024.118925_bib4","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/nprot.2013.032","article-title":"Mouse model of chronic and binge ethanol feeding (the NIAAA model)","volume":"8","author":"Bertola","year":"2013","journal-title":"Nat. Protoc."},{"issue":"3","key":"10.1016\/j.jep.2024.118925_bib5","doi-asserted-by":"crossref","DOI":"10.3390\/nu13031018","article-title":"The gut-liver Axis in cholestatic liver diseases","volume":"13","author":"Blesl","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.jep.2024.118925_bib6","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2021.725390","article-title":"Molecular and cellular mediators of the gut-liver Axis in the progression of liver diseases","volume":"8","author":"Bruneau","year":"2021","journal-title":"Front. Med."},{"issue":"3","key":"10.1016\/j.jep.2024.118925_bib7","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202201430R","article-title":"Echinacoside from Cistanche tubulosa ameliorates alcohol-induced liver injury and oxidative stress by targeting Nrf2","volume":"37","author":"Ding","year":"2023","journal-title":"FASEB J."},{"issue":"7783","key":"10.1016\/j.jep.2024.118925_bib8","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1038\/s41586-019-1742-x","article-title":"Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease","volume":"575","author":"Duan","year":"2019","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.jep.2024.118925_bib9","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1186\/s40168-017-0359-2","article-title":"Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease","volume":"5","author":"Dubinkina","year":"2017","journal-title":"Microbiome"},{"issue":"3","key":"10.1016\/j.jep.2024.118925_bib10","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.cld.2016.02.004","article-title":"Pathogenesis of alcoholic liver disease","volume":"20","author":"Dunn","year":"2016","journal-title":"Clin. Liver Dis."},{"key":"10.1016\/j.jep.2024.118925_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2021.153471","article-title":"Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota","volume":"83","author":"Fan","year":"2021","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.jep.2024.118925_bib12","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2392874","article-title":"Chronic binge drinking-induced susceptibility to colonic inflammation is microbiome-dependent","volume":"16","author":"Fonseca-Pereira","year":"2024","journal-title":"Gut Microb."},{"key":"10.1016\/j.jep.2024.118925_bib14","series-title":"Divine Farmer's Materia Medica [M]","year":"1956"},{"key":"10.1016\/j.jep.2024.118925_bib15","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2022.929776","article-title":"Dietary goji shapes the gut microbiota to prevent the liver injury induced by acute alcohol intake","volume":"9","author":"Guo","year":"2022","journal-title":"Front. Nutr."},{"issue":"5","key":"10.1016\/j.jep.2024.118925_bib16","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1007\/s11684-022-0960-z","article-title":"Role of Akkermansia muciniphila in the development of nonalcoholic fatty liver disease: current knowledge and perspectives","volume":"16","author":"Han","year":"2022","journal-title":"Front. Med."},{"issue":"1","key":"10.1016\/j.jep.2024.118925_bib17","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/hep.26321","article-title":"Deficiency of intestinal mucin-2 ameliorates experimental alcoholic liver disease in mice","volume":"58","author":"Hartmann","year":"2013","journal-title":"Hepatology"},{"issue":"5","key":"10.1016\/j.jep.2024.118925_bib18","doi-asserted-by":"crossref","first-page":"G310","DOI":"10.1152\/ajpgi.00094.2015","article-title":"Deficiency of intestinal mucin-2 protects mice from diet-induced fatty liver disease and obesity","volume":"310","author":"Hartmann","year":"2016","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"issue":"11","key":"10.1016\/j.jep.2024.118925_bib19","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1038\/s41579-023-00904-3","article-title":"The gut-liver axis and gut microbiota in health and liver disease","volume":"21","author":"Hsu","year":"2023","journal-title":"Nat. Rev. Microbiol."},{"issue":"4","key":"10.1016\/j.jep.2024.118925_bib20","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1136\/gutjnl-2020-321031","article-title":"Ginseng polysaccharides alter the gut microbiota and kynurenine\/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1\/programmed cell death ligand 1 (anti-PD-1\/PD-L1) immunotherapy","volume":"71","author":"Huang","year":"2022","journal-title":"Gut"},{"issue":"11","key":"10.1016\/j.jep.2024.118925_bib21","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22115717","article-title":"Pathophysiological aspects of alcohol metabolism in the liver","volume":"22","author":"Hyun","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2024.118925_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2022.913842","article-title":"Gut microbiota-modulating agents in alcoholic liver disease: links between host metabolism and gut microbiota","volume":"9","author":"Jung","year":"2022","journal-title":"Front. Med."},{"issue":"3","key":"10.1016\/j.jep.2024.118925_bib23","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.alcohol.2013.01.005","article-title":"Ethanol and dietary unsaturated fat (corn oil\/linoleic acid enriched) cause intestinal inflammation and impaired intestinal barrier defense in mice chronically fed alcohol","volume":"47","author":"Kirpich","year":"2013","journal-title":"Alcohol (Fayetteville, NY)"},{"key":"10.1016\/j.jep.2024.118925_bib24","doi-asserted-by":"crossref","first-page":"3289","DOI":"10.3389\/fmicb.2018.03289","article-title":"Comparative evaluation of microbiota engraftment following fecal microbiota transfer in mice models: age, kinetic and microbial status matter","volume":"9","author":"Le Roy","year":"2018","journal-title":"Front. Microbiol."},{"issue":"8","key":"10.1016\/j.jep.2024.118925_bib25","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1248\/cpb.c20-00057","article-title":"Herba Cistanche (Rou Cong Rong): a review of its Phytochemistry and pharmacology","volume":"68","author":"Lei","year":"2020","journal-title":"Chemical & pharmaceutical bulletin"},{"key":"10.1016\/j.jep.2024.118925_bib27","article-title":"Therapeutic potential and molecular mechanisms of echinacoside in neurodegenerative diseases","volume":"13","author":"Li","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"2","key":"10.1016\/j.jep.2024.118925_bib28","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1097\/HEP.0000000000000531","article-title":"GRP\/GRPR enhances alcohol-associated liver injury through the IRF1-mediated Caspase-1 inflammasome and NOX2-dependent ROS pathway","volume":"79","author":"Li","year":"2024","journal-title":"Hepatology"},{"issue":"5","key":"10.1016\/j.jep.2024.118925_bib29","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/s13238-020-00784-w","article-title":"Role of gut microbiota in identification of novel TCM-derived active metabolites","volume":"12","author":"Lin","year":"2021","journal-title":"Protein Cell"},{"issue":"20","key":"10.1016\/j.jep.2024.118925_bib30","doi-asserted-by":"crossref","first-page":"9249","DOI":"10.7150\/thno.46005","article-title":"Chronic ethanol consumption and HBV induce abnormal lipid metabolism through HBx\/SWELL1\/arachidonic acid signaling and activate Tregs in HBV-Tg mice","volume":"10","author":"Liu","year":"2020","journal-title":"Theranostics"},{"issue":"5","key":"10.1016\/j.jep.2024.118925_bib31","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1136\/gutjnl-2015-310585","article-title":"Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease","volume":"65","author":"Llopis","year":"2016","journal-title":"Gut"},{"key":"10.1016\/j.jep.2024.118925_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2023.120806","article-title":"Alginate oligosaccharide structures differentially affect DSS-induced colitis in mice by modulating gut microbiota","volume":"312","author":"Lu","year":"2023","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.jep.2024.118925_bib47","series-title":"Mechanism of Cistanche Deserticola Extract Echinacoside Inhibiting Malignant Phenotype of Hepatoma Cells[D]","author":"Ma","year":"2023"},{"key":"10.1016\/j.jep.2024.118925_bib33","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.660179","article-title":"The role of the gut-liver Axis in metabolic dysfunction-associated fatty liver disease","volume":"12","author":"Martin Mateos","year":"2021","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.jep.2024.118925_bib34","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1016\/j.bmc.2010.01.047","article-title":"Acylated phenylethanoid oligoglycosides with hepatoprotective activity from the desert plant Cistanche tubulosa","volume":"18","author":"Morikawa","year":"2010","journal-title":"Bioorg. Med. Chem."},{"issue":"7","key":"10.1016\/j.jep.2024.118925_bib35","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1248\/cpb.c19-00008","article-title":"A review of biologically active natural products from a desert plant Cistanche tubulosa","volume":"67","author":"Morikawa","year":"2019","journal-title":"Chem. Pharm. Bull. (Tokyo)"},{"issue":"12","key":"10.1016\/j.jep.2024.118925_bib36","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1136\/gutjnl-2020-322260","article-title":"Mucus barrier, mucins and gut microbiota: the expected slimy partners?","volume":"69","author":"Paone","year":"2020","journal-title":"Gut"},{"issue":"Dec 9","key":"10.1016\/j.jep.2024.118925_bib37","article-title":"Effect of PhenylEthanol glycosides from Cistanche tubulosa on autophagy and apoptosis in H22 tumor-bearing mice","volume":"2022","author":"Qi","year":"2022","journal-title":"Evid Based Complement Alternat Med"},{"issue":"2","key":"10.1016\/j.jep.2024.118925_bib38","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.toxlet.2014.11.027","article-title":"Dissolution of lipids from mucus: a possible mechanism for prompt disruption of gut barrier function by alcohol","volume":"232","author":"Qin","year":"2015","journal-title":"Toxicol. Lett."},{"issue":"1","key":"10.1016\/j.jep.2024.118925_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/19490976.2021.1927633","article-title":"Gut Akkermansia muciniphila ameliorates metabolic dysfunction-associated fatty liver disease by regulating the metabolism of L-aspartate via gut-liver axis","volume":"13","author":"Rao","year":"2021","journal-title":"Gut Microb."},{"issue":"7","key":"10.1016\/j.jep.2024.118925_bib40","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.chom.2022.05.004","article-title":"Interspecies commensal interactions have nonlinear impacts on host immunity","volume":"30","author":"Rice","year":"2022","journal-title":"Cell Host Microbe"},{"issue":"3","key":"10.1016\/j.jep.2024.118925_bib41","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/med.21768","article-title":"Cistanches Herba, from an endangered species to a big brand of Chinese medicine","volume":"41","author":"Song","year":"2021","journal-title":"Med. Res. Rev."},{"issue":"4","key":"10.1016\/j.jep.2024.118925_bib42","doi-asserted-by":"crossref","DOI":"10.1080\/21688370.2017.1373208","article-title":"C\u00e2mara NOS. Intestinal barrier and gut microbiota: shaping our immune responses throughout life","volume":"5","author":"Takiishi","year":"2017","journal-title":"Tissue Barriers"},{"issue":"1","key":"10.1016\/j.jep.2024.118925_bib43","doi-asserted-by":"crossref","first-page":"5","DOI":"10.35946\/arcr.v41.1.05","article-title":"Natural recovery by the liver and other organs after chronic alcohol use","volume":"41","author":"Thomes","year":"2021","journal-title":"Alcohol Res. Curr. Rev."},{"issue":"7834","key":"10.1016\/j.jep.2024.118925_bib44","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/s41586-020-2881-9","article-title":"Host variables confound gut microbiota studies of human disease","volume":"587","author":"Vujkovic Cvijin","year":"2020","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.jep.2024.118925_bib45","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1002\/hep.27406","article-title":"The global burden of liver disease: the major impact of China","volume":"60","author":"Wang","year":"2014","journal-title":"Hepatology"},{"key":"10.1016\/j.jep.2024.118925_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2024.114489","article-title":"Solanum nigrum L. berries extract ameliorated the alcoholic liver injury by regulating gut microbiota, lipid metabolism, inflammation, and oxidative stress","volume":"188","author":"Wang","year":"2024","journal-title":"Food Res. Int."},{"key":"10.1016\/j.jep.2024.118925_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.fitote.2022.105227","article-title":"A pair of novel phenylethanol glycosides from Cistanche tubulosa (Schenk) Wight","volume":"160","author":"Xiong","year":"2022","journal-title":"Fitoterapia"},{"issue":"2","key":"10.1016\/j.jep.2024.118925_bib49","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/biof.1469","article-title":"Chronic alcohol exposure induced gut microbiota dysbiosis and its correlations with neuropsychic behaviors and brain BDNF\/Gabra1 changes in mice","volume":"45","author":"Xu","year":"2019","journal-title":"Biofactors"},{"key":"10.1016\/j.jep.2024.118925_bib50","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/s40199-015-0135-4","article-title":"Preventive effects of phenylethanol glycosides from Cistanche tubulosa on bovine serum albumin-induced hepatic fibrosis in rats","volume":"23","author":"You","year":"2015","journal-title":"Daru"},{"key":"10.1016\/j.jep.2024.118925_bib51","doi-asserted-by":"crossref","DOI":"10.1177\/15347354211013085","article-title":"Cistanche tubulosa phenylethanoid glycosides induce apoptosis of hepatocellular carcinoma cells by mitochondria-dependent and MAPK pathways and enhance antitumor effect through combination with cisplatin","volume":"20","author":"Yuan","year":"2021","journal-title":"Integr. Cancer Ther."},{"key":"10.1016\/j.jep.2024.118925_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2019.115038","article-title":"A galactoglucan isolated from of Cistanche deserticola Y. C. Ma. and its bioactivity on intestinal bacteria strains","volume":"223","author":"Zeng","year":"2019","journal-title":"Carbohydr. Polym."},{"issue":"3","key":"10.1016\/j.jep.2024.118925_bib53","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.chom.2023.02.001","article-title":"Candida albicans-specific Th17 cell-mediated response contributes to alcohol-associated liver disease","volume":"31","author":"Zeng","year":"2023","journal-title":"Cell Host Microbe"},{"issue":"5","key":"10.1016\/j.jep.2024.118925_bib13","first-page":"397","article-title":"The course of professor Wang Lingtai\u2019s kidney tonifying therapy in the treatment of chronic hepatitis B","volume":"32","author":"Zhao","year":"2022","journal-title":"Chin. J. Integr. Tradit. West. Med. Liver Dis."},{"issue":"2","key":"10.1016\/j.jep.2024.118925_bib55","first-page":"539","article-title":"The triangular relationship between traditional Chinese medicines, intestinal flora, and colorectal cancer","volume":"44","author":"Zou","year":"2023","journal-title":"Med. Res."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874124012248?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874124012248?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T10:56:08Z","timestamp":1731322568000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874124012248"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":53,"alternative-id":["S0378874124012248"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2024.118925","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Protective effects of phenylethanol glycosides from Cistanche tubulosa against ALD through modulating gut microbiota homeostasis","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2024.118925","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"118925"}}