{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:43:59Z","timestamp":1786992239586,"version":"build-2736575974"},"reference-count":76,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003545","name":"Minist\u00e9rio da Ci\u00eancia, Tecnologia e Inova\u00e7\u00e3o","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003545","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008532","name":"Universidade Federal do Rio Grande do Norte","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008532","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordination of Higher Education Personnel Improvement","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.jep.2024.118932","type":"journal-article","created":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T20:16:08Z","timestamp":1728591368000},"page":"118932","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"P3","title":["Bioactivity of Talisia esculenta extracts: Antioxidant and anti-inflammatory action on RAW 264.7 macrophages and protective potential on the zebrafish exposed to oxidative stress inducers"],"prefix":"10.1016","volume":"337","author":[{"given":"Maria L\u00facia da Silva","family":"Cordeiro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5266-9038","authenticated-orcid":false,"given":"Ver\u00f4nica Giuliani de","family":"Queiroz Aquino-Martins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0257-9882","authenticated-orcid":false,"given":"Ariana Pereira da","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2022-5659","authenticated-orcid":false,"given":"Weslley de Souza","family":"Paiva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6189-1490","authenticated-orcid":false,"given":"Maylla Maria Correia Leite","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3294-7859","authenticated-orcid":false,"given":"Ana Carolina","family":"Luchiari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2252-1221","authenticated-orcid":false,"given":"Hugo Alexandre Oliveira","family":"Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4690-2785","authenticated-orcid":false,"given":"Katia Castanho","family":"Scortecci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2024.118932_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.113881","article-title":"In-vivo anti-inflammatory activity and safety assessment of the aqueous extract of Algerian Erica arborea L. (Ericaceae) aerial parts","volume":"271","author":"Amroun","year":"2021","journal-title":"J. Ethnopharmacol."},{"issue":"10","key":"10.1016\/j.jep.2024.118932_bib2","doi-asserted-by":"crossref","first-page":"439","DOI":"10.3390\/antiox8100439","article-title":"In vitro antioxidant, anti-biofilm, and solar protection activities of melocactus zehntneri (britton & rose) pulp extract","volume":"8","author":"Aquino-Martins","year":"2019","journal-title":"Antioxidants"},{"issue":"18","key":"10.1016\/j.jep.2024.118932_bib3","doi-asserted-by":"crossref","first-page":"4089","DOI":"10.3390\/molecules25184089","article-title":"Anti-inflammatory activity and ROS regulation effect of sinapaldehyde in LPS-stimulated RAW 264.7 macrophages","volume":"25","author":"Baek","year":"2020","journal-title":"Molecules"},{"issue":"5","key":"10.1016\/j.jep.2024.118932_bib4","doi-asserted-by":"crossref","first-page":"234","DOI":"10.3390\/md18050234","article-title":"Immunostimulatory effect of sulfated galactans from the green seaweed caulerpa cupressoides var. flabellata","volume":"18","author":"Barbosa","year":"2020","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.jep.2024.118932_bib5","article-title":"Ethnopharmacology of medicinal plants of the pantanal region (mato grosso, Brazil)","volume":"2012","author":"Bieski","year":"2012","journal-title":"Evid. base Compl. Alternative Med."},{"issue":"10","key":"10.1016\/j.jep.2024.118932_bib6","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.3390\/plants9101345","article-title":"Zebrafish as a successful animal model for screening toxicity of medicinal plants","volume":"9","author":"Chahardehi","year":"2020","journal-title":"Plants"},{"key":"10.1016\/j.jep.2024.118932_bib7","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.12933","article-title":"Antioxidant and anti-inflammatory activities of durian (Durio zibethinus Murr.) pulp, seed and peel flour","volume":"10","author":"Charoenphun","year":"2022","journal-title":"PeerJ"},{"issue":"4","key":"10.1016\/j.jep.2024.118932_bib8","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3103\/S009639251804003X","article-title":"Role of reactive oxygen species in inflammation: a minireview","volume":"73","author":"Chelombitko","year":"2018","journal-title":"Moscow Univ. Biol. Sci. Bull."},{"key":"10.1016\/j.jep.2024.118932_bib9","first-page":"939","article-title":"Antioxidant and anti-inflammatory activities of durian and rambutan pulp extract","volume":"23","author":"Chingsuwanrote","year":"2016","journal-title":"Int. Food Res. J."},{"issue":"17","key":"10.1016\/j.jep.2024.118932_bib10","doi-asserted-by":"crossref","first-page":"3855","DOI":"10.3390\/nu15173855","article-title":"Exploring the antioxidant potential of Talisia esculenta using in vitro and in vivo approaches","volume":"15","author":"Cordeiro","year":"2023","journal-title":"Nutrients"},{"issue":"21","key":"10.1016\/j.jep.2024.118932_bib11","doi-asserted-by":"crossref","DOI":"10.3390\/ijms242115885","article-title":"The antioxidant and immunomodulatory potential of coccoloba alnifolia leaf extracts","volume":"24","author":"De Melo","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"7","key":"10.1016\/j.jep.2024.118932_bib12","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.3390\/ani13071223","article-title":"The importance of animal models in biomedical research: current insights and applications","volume":"13","author":"Dom\u00ednguez-Oliva","year":"2023","journal-title":"Animals (Basel)"},{"key":"10.1016\/j.jep.2024.118932_bib13","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.phrs.2016.01.021","article-title":"Medicinal plants in Brazil: pharmacological studies, drug discovery, challenges and perspectives","volume":"112","author":"Dutra","year":"2016","journal-title":"Pharmacol. Res."},{"issue":"20","key":"10.1016\/j.jep.2024.118932_bib14","doi-asserted-by":"crossref","first-page":"7660","DOI":"10.3390\/ijms21207660","article-title":"Copper toxicity links to pathogenesis of alzheimer's disease and therapeutics approaches","volume":"21","author":"Ejaz","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2024.118932_bib15","article-title":"Mass spectrometry characterization, antioxidant activity, and cytotoxicity of the peel and pulp extracts of Pitomba","volume":"340","author":"Fraga","year":"2021","journal-title":"Food Chem."},{"issue":"2","key":"10.1016\/j.jep.2024.118932_bib16","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1177\/1091581814523142","article-title":"Toxicity assessment of 7 anticancer compounds in zebrafish","volume":"33","author":"Gao","year":"2014","journal-title":"Int. J. Toxicol."},{"key":"10.1016\/j.jep.2024.118932_bib17","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.809952","article-title":"Dissecting the crosstalk between Nrf2 and NF-\u03baB response pathways in drug-induced toxicity","volume":"9","author":"Gao","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"issue":"2","key":"10.1016\/j.jep.2024.118932_bib18","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1590\/1809-4392200332242","article-title":"Repert\u00f3rio bot\u00e2nico da pitombeira (Talisia esculenta (St.-Hil.) Radlk. - Sapindaceae)","volume":"33","author":"Guarim Neto","year":"2003","journal-title":"Acta Amazonica"},{"key":"10.1016\/j.jep.2024.118932_bib19","first-page":"1491","article-title":"Efeitos inibit\u00f3rios sin\u00e9rgicos in vitro de combina\u00e7\u00f5es de extratos vegetais no crescimento bacteriano de Staphylococcus aureus resistente \u00e0 meticilina","volume":"16","author":"Jeong","year":"2023","journal-title":"Farmac\u00eauticos"},{"key":"10.1016\/j.jep.2024.118932_bib20","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3389\/fcvm.2020.00012","article-title":"Mitochondrial ROS formation in the pathogenesis of diabetic cardiomyopathy","volume":"7","author":"Kaludercic","year":"2020","journal-title":"Front Cardiovasc Med"},{"issue":"1","key":"10.1016\/j.jep.2024.118932_bib21","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1515\/labmed-2021-0099","article-title":"Evaluation of antioxidant and antiinflammatory activity of ethanolic extracts of Polygonum senticosum in lipopolysaccharide-induced RAW 264.7 macrophages","volume":"46","author":"Kim","year":"2022","journal-title":"J. Lab. Med."},{"key":"10.1016\/j.jep.2024.118932_bib22","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.fsi.2020.10.017","article-title":"Anti-inflammatory effects of methanol extracts from the Antarctic lichen, Amandinea sp. in LPS-stimulated raw 264.7 macrophages and zebrafish","volume":"107","author":"Kim","year":"2020","journal-title":"Fish Shellfish Immunol."},{"issue":"1","key":"10.1016\/j.jep.2024.118932_bib23","doi-asserted-by":"crossref","first-page":"112","DOI":"10.3390\/antiox10010112","article-title":"Antioxidant effects of turmeric leaf extract against hydrogen peroxide-induced oxidative stress in vitro in vero cells and in vivo in zebrafish","volume":"10","author":"Kim","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.jep.2024.118932_bib24","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.3390\/antiox10081324","article-title":"5-Hydroxymaltol derived from beetroot juice through lactobacillus fermentation suppresses inflammatory effect and oxidant stress via regulating NF-kB, MAPKs pathway and NRF2\/HO-1 expression","volume":"10","author":"Kim","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.jep.2024.118932_bib25","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.carbpol.2013.11.022","article-title":"Protective effect of fucoidan against AAPH-induced oxidative stress in zebrafish model","volume":"102","author":"Kim","year":"2014","journal-title":"Carbohydr. Polym."},{"issue":"3","key":"10.1016\/j.jep.2024.118932_bib26","doi-asserted-by":"crossref","first-page":"620","DOI":"10.5530\/pj.2021.13.78","article-title":"In vitro and in vivo AntiInflammatory evaluation of the whole plant extracts of Crotalaria biflora (L)","volume":"13","author":"Kumar","year":"2021","journal-title":"Pharmacog J"},{"key":"10.1016\/j.jep.2024.118932_bib27","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jep.2015.12.044","article-title":"Longan (Dimocarpus longan Lour.) inhibits lipopolysaccharide-stimulated nitric oxide production in macrophages by suppressing NF-\u03baB and AP-1 signaling pathways","volume":"179","author":"Kunworarath","year":"2016","journal-title":"J. Ethnopharmacol."},{"issue":"12","key":"10.1016\/j.jep.2024.118932_bib28","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.3390\/biomedicines9121784","article-title":"Inflammatory, oxidative stress, and apoptosis effects in zebrafish larvae after rapid exposure to a commercial glyphosate formulation","volume":"9","author":"Lanzarin","year":"2021","journal-title":"Biomedicines"},{"key":"10.1016\/j.jep.2024.118932_bib29","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.3390\/antiox12061297","article-title":"Anti-inflammatory, anti-oxidative and anti-apoptotic effects of thymol and 24-epibrassinolide in zebrafish larvae","volume":"12","author":"Lanzarin","year":"2023","journal-title":"Antioxidants"},{"issue":"4","key":"10.1016\/j.jep.2024.118932_bib30","doi-asserted-by":"crossref","first-page":"690","DOI":"10.3390\/antiox11040690","article-title":"Lycopus maackianus makino MeOH extract exhibits antioxidant and anti-neuroinflammatory effects in neuronal cells and zebrafish model","volume":"11","author":"Lee","year":"2022","journal-title":"Antioxidants"},{"key":"10.1016\/j.jep.2024.118932_bib31","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.cbi.2018.02.022","article-title":"Kaempferol 7-O-\u03b2-D-glucoside isolated from the leaves of Cudrania tricuspidata inhibits LPS-induced expression of pro-inflammatory mediators through inactivation of NF-\u03baB, AP-1, and JAK-STAT in RAW 264.7 macrophages","volume":"284","author":"Lee","year":"2018","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.jep.2024.118932_bib32","doi-asserted-by":"crossref","first-page":"166","DOI":"10.3389\/fnbeh.2019.00166","article-title":"Individual differences in hatching time predict alcohol response in zebrafish","volume":"13","author":"Leite-Ferreira","year":"2019","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.jep.2024.118932_bib33","doi-asserted-by":"crossref","DOI":"10.1038\/nplants.2017.109","article-title":"Demystifying traditional herbal medicine with modern approach","volume":"3","author":"Li","year":"2017","journal-title":"Nat. Plants"},{"key":"10.1016\/j.jep.2024.118932_bib34","article-title":"Anti-inflammatory effects and mechanisms of dandelion in RAW264.7 macrophages and zebrafish larvae","volume":"13","author":"Li","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2024.118932_bib35","doi-asserted-by":"crossref","first-page":"477","DOI":"10.3389\/fphys.2018.00477","article-title":"Role of ROS and nutritional antioxidants in human diseases","volume":"9","author":"Liu","year":"2018","journal-title":"Front. Physiol."},{"issue":"3","key":"10.1016\/j.jep.2024.118932_bib36","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.pnpbp.2010.05.004","article-title":"A review on the oxidative andnitrosative stress (O&NS) pathways in major depression and their possiblecontribution to the (neuro) degenerative processes in that illness","volume":"35","author":"Maes","year":"2011","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.jep.2024.118932_bib37","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s12950-015-0055-6","volume":"12","author":"Marimoutou","year":"2015","journal-title":"J. Inflamm."},{"issue":"2","key":"10.1016\/j.jep.2024.118932_bib38","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1007\/s10787-022-00924-0","article-title":"In vitro and in vivo anti-inflammatory and anticoagulant activities of Myrciaria plinioides D. Legrand ethanol leaf extract","volume":"30","author":"Marmitt","year":"2022","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.jep.2024.118932_bib39","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.semcdb.2017.05.023","article-title":"ROS signalling in the biology of cancer","volume":"80","author":"Moloney","year":"2018","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.jep.2024.118932_bib40","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","article-title":"Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays","volume":"65","author":"Mosmann","year":"1983","journal-title":"J. Immunol. Methods"},{"issue":"3","key":"10.1016\/j.jep.2024.118932_bib41","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s13237-022-00405-3","article-title":"Plant-derived natural products for drug discovery: current approaches and prospects","volume":"65","author":"Nasim","year":"2022","journal-title":"Nucleus: an international journal of cytology and allied topics"},{"issue":"3","key":"10.1016\/j.jep.2024.118932_bib42","doi-asserted-by":"crossref","first-page":"192","DOI":"10.3390\/antiox9030192","article-title":"Anti-inflammatory and antioxidant properties of the ethanol extract of clerodendrum cyrtophyllum turcz in copper sulfate-induced inflammation in zebrafish","volume":"9","author":"Nguyen","year":"2020","journal-title":"Antioxidants"},{"issue":"16","key":"10.1016\/j.jep.2024.118932_bib43","doi-asserted-by":"crossref","first-page":"3726","DOI":"10.3390\/molecules25163726","article-title":"Plants as sources of anti-inflammatory agents","volume":"25","author":"Nunes","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2024.118932_bib44","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1287580","article-title":"Antinociceptive effect of Nephelium lappaceum L. fruit peel and the participation of nitric oxide, opioid receptors, and ATP-sensitive potassium channels","volume":"14","author":"Oliveira","year":"2023","journal-title":"Front. Pharmacol."},{"issue":"3","key":"10.1016\/j.jep.2024.118932_bib45","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.jep.2010.04.018","article-title":"Antioxidant properties of Baccharis trimera in the neutrophils of Fisher rats","volume":"129","author":"P\u00e1dua","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.118932_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2023.114091","article-title":"Assessment of acute toxicity of crude extract rich in carotenoids from Cantaloupe melon (Cucumis melo L.) and the gelatin-based nanoparticles using the zebrafish (Danio rerio) model","volume":"181","author":"Pais","year":"2023","journal-title":"Food Chem. Toxicol."},{"issue":"8","key":"10.1016\/j.jep.2024.118932_bib47","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1038\/s41573-021-00210-8","article-title":"Zebrafish disease models in drug discovery: from preclinical modelling to clinical trials","volume":"20","author":"Patton","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"issue":"23","key":"10.1016\/j.jep.2024.118932_bib48","doi-asserted-by":"crossref","first-page":"9149","DOI":"10.3390\/ijms21239149","article-title":"Use of H2O2 to cause oxidative stress, the catalase issue","volume":"21","author":"Ransy","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2024.118932_bib49","doi-asserted-by":"crossref","first-page":"227","DOI":"10.3390\/inorganics11060227","article-title":"Oxida\u00e7\u00e3o de Fosfolip\u00eddios por Radical OH Coordenado ao Pept\u00eddeo Amiloide-\u03b2 de Cobre - Uma Modelagem de Teoria Funcional de Densidade","volume":"11","author":"Rovetta","year":"2023","journal-title":"Inorg\u00e2nicos"},{"key":"10.1016\/j.jep.2024.118932_bib50","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/2573580","article-title":"Antioxidant, cytotoxic, and antiproliferative activities and total polyphenol contents of the extracts of Geissospermum reticulatum bark","volume":"2016","author":"Sajkowska-Kozielewicz","year":"2016","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.jep.2024.118932_bib51","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/s41420-018-0109-7","article-title":"Zebrafish: an emerging real-time model system to study Alzheimer's disease and neurospecific drug discovery","volume":"4","author":"Saleem","year":"2018","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.jep.2024.118932_bib52","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/1941285","article-title":"The good, the bad, and the ugly of ROS: new insights on aging and aging-related diseases from eukaryotic and prokaryotic model organisms","volume":"2018","author":"Santos","year":"2018","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.jep.2024.118932_bib53","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s00393-020-00951-8","article-title":"Interaction of pain and chronic inflammation","volume":"80","author":"Seifert","year":"2021","journal-title":"Z. Rheumatol."},{"key":"10.1016\/j.jep.2024.118932_bib54","doi-asserted-by":"crossref","first-page":"107","DOI":"10.7324\/JAPS.2019.90514","article-title":"Teratogenic effects of aqueous extract of Ficus glomerata leaf during embryonic development in zebrafish (Danio rerio)","volume":"9","author":"Shaikh","year":"2019","journal-title":"J. Appl. Pharmaceut. Sci."},{"issue":"2","key":"10.1016\/j.jep.2024.118932_bib55","doi-asserted-by":"crossref","first-page":"352","DOI":"10.3390\/plants10020352","article-title":"COVID-19 crisis: how can plant Biotechnology help?","volume":"10","author":"Shohag","year":"2021","journal-title":"Plants"},{"issue":"2","key":"10.1016\/j.jep.2024.118932_bib56","doi-asserted-by":"crossref","DOI":"10.1590\/0001-3765201920180117","article-title":"Plant extracts display synergism with different classes of antibiotics","volume":"91","author":"Silva","year":"2019","journal-title":"An. Acad. Bras. Cienc."},{"key":"10.1016\/j.jep.2024.118932_bib57","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.ijbiomac.2022.07.110","article-title":"Comparison of in vitro and in vivo antioxidant activities of commercial fucoidans from Macrocystis pyrifera, Undaria pinnatifida, and Fucus vesiculosus","volume":"216","author":"Silva","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jep.2024.118932_bib58","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.ejphar.2018.07.055","article-title":"Rutin restricts hydrogen peroxide-induced alterations by up-regulating the redox-system: an in vitro, in vivo and in silico study","volume":"835","author":"Singh","year":"2018","journal-title":"Eur. J. Pharmacol."},{"issue":"8","key":"10.1016\/j.jep.2024.118932_bib76","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.3390\/molecules24081583","article-title":"Oxidative Stress: A Key Modulator in Neurodegenerative Diseases","volume":"24","author":"Singh","year":"2019","journal-title":"Molecules (Basel, Switzerland)"},{"issue":"22","key":"10.1016\/j.jep.2024.118932_bib59","doi-asserted-by":"crossref","first-page":"6949","DOI":"10.3390\/molecules26226949","article-title":"Quercetin prevents LPS-induced oxidative stress and inflammation by modulating NOX2\/ROS\/NF-kB in lung epithelial cells","volume":"26","author":"Sul","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2024.118932_bib60","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.jep.2016.08.053","article-title":"Anti-inflammatory, antioxidant and anti-Mycobacterium tuberculosis activity of viridiflorol: the major constituent of Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk","volume":"192","author":"Trevizan","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.118932_bib61","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.jep.2019.02.048","article-title":"Aqueous and methanol extracts of Paullinia pinnata L. (Sapindaceae) improve inflammation, pain and histological features in CFA-induced mono-arthritis: evidence from in vivo and in vitro studies","volume":"2019","author":"Tseuguem","year":"2019","journal-title":"Ethnopharmacol"},{"issue":"4","key":"10.1016\/j.jep.2024.118932_bib62","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1590\/1809-4392201400423","article-title":"Etnobot\u00e2nica de plantas medicinais em comunidades ribeirinhas do Munic\u00edpio de Manacapuru, Amazonas, Brasil","volume":"44","author":"V\u00e1squez","year":"2014","journal-title":"Acta Amazonica"},{"issue":"9","key":"10.1016\/j.jep.2024.118932_bib63","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.3390\/ph16091209","article-title":"Antioxidant effects of quercetin nanocrystals in nanosuspension against hydrogen peroxide-induced oxidative stress in a zebrafish model","volume":"16","author":"Wang","year":"2023","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.jep.2024.118932_bib64","article-title":"Acute toxicity of leaf extracts of enydra fluctuans lour in zebrafish (Danio rerio Hamilton)","volume":"2020","author":"Xavier","year":"2020","journal-title":"Sci. Tech. Rep."},{"issue":"13","key":"10.1016\/j.jep.2024.118932_bib65","doi-asserted-by":"crossref","first-page":"6157","DOI":"10.1039\/D3FO01098H","article-title":"The molecular mechanism of three novel peptides from C-phycocyanin alleviates MPTP-induced Parkinson's disease-like pathology in zebrafish","volume":"14","author":"Xu","year":"2023","journal-title":"Food Funct."},{"issue":"11","key":"10.1016\/j.jep.2024.118932_bib66","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.3390\/nu10111618","article-title":"The immunomodulatory and anti-inflammatory role of polyphenols","volume":"10","author":"Yahfoufi","year":"2018","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jep.2024.118932_bib67","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-70962-7","article-title":"The effects of Piper sarmentosum aqueous extracts on zebrafish (Danio rerio) embryos and caudal fin tissue regeneration","volume":"10","author":"Zainol Abidin","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2024.118932_bib68","doi-asserted-by":"crossref","first-page":"582","DOI":"10.3390\/biom10040582","article-title":"Anti-inflammatory activity of exopolysaccharides from phormidium sp. ETS05, the most abundant cyanobacterium of the therapeutic euganean thermal muds, using the zebrafish model","volume":"10","author":"Zampieri","year":"2020","journal-title":"Biomolecules"},{"key":"10.1016\/j.jep.2024.118932_bib69","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jare.2021.06.023","article-title":"Activation of Nrf2\/HO-1 signaling: an important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress","volume":"34","author":"Zhang","year":"2021","journal-title":"J. Adv. Res."},{"issue":"2","key":"10.1016\/j.jep.2024.118932_bib70","doi-asserted-by":"crossref","first-page":"391","DOI":"10.3390\/antiox12020391","article-title":"Anti-inflammatory and antioxidant properties of \u03b2-sitosterol in copper sulfate-induced inflammation in zebrafish (Danio rerio)","volume":"12","author":"Zhang","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.jep.2024.118932_bib71","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.1098725","article-title":"Role of inflammation, immunity, and oxidative stress in hypertension: new insights and potential therapeutic targets","volume":"13","author":"Zhang","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jep.2024.118932_bib72","article-title":"Sheng-Mai Yin exerts anti-inflammatory effects on RAW 264.7 cells and zebrafish","volume":"267","author":"Zheng","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2024.118932_bib73","doi-asserted-by":"crossref","first-page":"38541","DOI":"10.1039\/C6RA02843H","article-title":"Generation of hydrogen peroxide and hydroxyl radical resulting from oxygen-dependent oxidation of l-ascorbic acid via copper redox-catalyzed reactions","volume":"6","author":"Zhou","year":"2016","journal-title":"RSC Adv."},{"key":"10.1016\/j.jep.2024.118932_bib74","doi-asserted-by":"crossref","first-page":"933","DOI":"10.3109\/02713683.2015.1082186","article-title":"Protective effect of rutin against H2O2-induced oxidative stress and apoptosis in human lens epithelial cells","volume":"41","author":"Zhou","year":"2016","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.jep.2024.118932_bib75","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.fct.2017.01.022","article-title":"Protective effects of rambutan (Nephelium lappaceum) peel phenolics on H2O2-induced oxidative damages in HepG2 cells and d-galactose-induced aging mice","volume":"108","author":"Zhuang","year":"2017","journal-title":"Food Chem. Toxicol."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874124012315?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874124012315?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T10:56:20Z","timestamp":1731322580000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874124012315"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":76,"alternative-id":["S0378874124012315"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2024.118932","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bioactivity of Talisia esculenta extracts: Antioxidant and anti-inflammatory action on RAW 264.7 macrophages and protective potential on the zebrafish exposed to oxidative stress inducers","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2024.118932","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"118932"}}