{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T20:08:35Z","timestamp":1791922115770,"version":"4.3.4"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,19]],"date-time":"2025-07-19T00:00:00Z","timestamp":1752883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001322","name":"South African Medical Research Council","doi-asserted-by":"publisher","award":["23015"],"award-info":[{"award-number":["23015"]}],"id":[{"id":"10.13039\/501100001322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007782","name":"Tshwane University of Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007782","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001321","name":"National Research Foundation","doi-asserted-by":"publisher","award":["86923"],"award-info":[{"award-number":["86923"]}],"id":[{"id":"10.13039\/501100001321","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001321","name":"National Research Foundation","doi-asserted-by":"publisher","award":["TTK230105669155"],"award-info":[{"award-number":["TTK230105669155"]}],"id":[{"id":"10.13039\/501100001321","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.jep.2025.120314","type":"journal-article","created":{"date-parts":[[2025,7,19]],"date-time":"2025-07-19T06:31:46Z","timestamp":1752906706000},"page":"120314","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"PA","title":["Neuroprotective and neurorestorative properties of Mesembryanthemum tortuosum in a Parkinson's disease zebrafish larvae model"],"prefix":"10.1016","volume":"353","author":[{"given":"Keagile","family":"Lepule","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxleene","family":"Sandasi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiyang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6810-2981","authenticated-orcid":false,"given":"Alvaro","family":"Viljoen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2025.120314_bib1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0054166","article-title":"Validation of the zebrafish pentylenetetrazol seizure model: locomotor versus electrographic responses to antiepileptic drugs","volume":"8","author":"Afrikanova","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2025.120314_bib2","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.neuropharm.2012.08.023","article-title":"Selective inhibition of monoamine oxidase A or B reduces striatal oxidative stress in rats with partial depletion of the nigro-striatal dopaminergic pathway","volume":"65","author":"Aluf","year":"2013","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.jep.2025.120314_bib3","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1001\/jama.2019.22360","article-title":"Diagnosis and treatment of Parkinson disease: a review","volume":"323","author":"Armstrong","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.jep.2025.120314_bib60","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/imm.12233","article-title":"Inflammation in neurodegenerative diseases\u2013an update","volume":"142","author":"Amor","year":"2014","journal-title":"Immunology"},{"key":"10.1016\/j.jep.2025.120314_bib4","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2022.890838","article-title":"Neuroprotective properties of bis-sulfonamide derivatives against 6-OHDA-induced Parkinson's model via sirtuin 1 activity and in silico pharmacokinetic properties","volume":"15","author":"Apiraksattayakul","year":"2022","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.jep.2025.120314_bib5","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1007\/s13105-018-0620-6","article-title":"Sceletium tortuosum may delay chronic disease progression via alkaloid-dependent antioxidant or anti-inflammatory action","volume":"74","author":"Bennett","year":"2018","journal-title":"J. Physiol. Biochem."},{"key":"10.1016\/j.jep.2025.120314_bib6","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.4957","article-title":"N-acetylcysteine protects against motor, optomotor and morphological deficits induced by 6-OHDA in zebrafish larvae","volume":"6","author":"Benvenutti","year":"2018","journal-title":"PeerJ"},{"key":"10.1016\/j.jep.2025.120314_bib7","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0301-0082(01)00003-X","article-title":"Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease","volume":"65","author":"Blum","year":"2001","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.jep.2025.120314_bib8","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.alcohol.2004.08.002","article-title":"Chronic ethanol ingestion and the risk of acute lung injury: a role for glutathione availability?","volume":"33","author":"Brown","year":"2004","journal-title":"Alcohol"},{"key":"10.1016\/j.jep.2025.120314_bib9","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.sajb.2018.10.011","article-title":"To ferment or not to ferment Sceletium tortuosum \u2013 Do our ancestors hold the answer?","volume":"122","author":"Chen","year":"2019","journal-title":"South Afr. J. Bot."},{"key":"10.1016\/j.jep.2025.120314_bib10","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.jep.2015.11.034","article-title":"High-mesembrine Sceletium extract (Trimesemine\u2122) is a monoamine releasing agent, rather than only a selective serotonin reuptake inhibitor","volume":"177","author":"Coetzee","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib11","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.neuroscience.2017.10.018","article-title":"Neuroprotective and neuro-restorative effects of minocycline and rasagiline in a zebrafish 6-hydroxydopamine model of Parkinson's disease","volume":"367","author":"Cronin","year":"2017","journal-title":"Neurosciences"},{"key":"10.1016\/j.jep.2025.120314_bib12","doi-asserted-by":"crossref","first-page":"461","DOI":"10.3233\/JPD-130230","article-title":"The role of oxidative stress in Parkinson's disease","volume":"3","author":"Dias","year":"2013","journal-title":"J. Parkinsons Dis."},{"key":"10.1016\/j.jep.2025.120314_bib61","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.jep.2018.05.010","article-title":"Effect of Zembrin\u00ae and four of its alkaloid constituents on electric excitability of the rat hippocampus","volume":"223","author":"Dimpfel","year":"2018","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib14","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.3390\/antiox10101641","article-title":"Highly potent, selective, and competitive indole-based MAO-B inhibitors protect PC12 cells against 6-hydroxydopamine-and rotenone-induced oxidative stress","volume":"10","author":"Elsherbeny","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.jep.2025.120314_bib62","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1089\/zeb.2013.0950","article-title":"Effects of 6-hydroxydopamine exposure on motor activity and biochemical expression in zebrafish (Danio rerio) larvae","volume":"11","author":"Feng","year":"2014","journal-title":"Zebrafish"},{"key":"10.1016\/j.jep.2025.120314_bib15","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1385\/JMN:14:3:147","article-title":"Depletion of brain glutathione potentiates the effect of 6-hydroxydopamine in a rat model of Parkinson's disease","volume":"14","author":"Garc\u00eda","year":"2000","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.jep.2025.120314_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.117113","article-title":"Sceletium tortuosum-derived mesembrine significantly contributes to the anxiolytic effect of Zembrin\u00ae, but its anti-depressant effect may require synergy of multiple plant constituents","volume":"319","author":"Gericke","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114550","article-title":"An acute dose-ranging evaluation of the antidepressant properties of Sceletium tortuosum (Zembrin\u00ae) versus escitalopram in the Flinders Sensitive Line rat","volume":"284","author":"Gericke","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib19","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.jep.2008.07.043","article-title":"Sceletium\u2014a review update","volume":"119","author":"Gericke","year":"2008","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpc.2023.109630","article-title":"Protective effects of 24-epibrassinolide against the 6-OHDA zebrafish model of Parkinson's disease","volume":"269","author":"Gomes","year":"2023","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib22","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/j.1365-2125.2012.04272.x","article-title":"The antioxidant paradox: less paradoxical now?","volume":"75","author":"Halliwell","year":"2013","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib23","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.jep.2011.07.035","article-title":"Pharmacological actions of the South African medicinal and functional food plant Sceletium tortuosum and its principal alkaloids","volume":"137","author":"Harvey","year":"2011","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib24","series-title":"Lippincott's Illustrated Reviews: Pharmacology","author":"Harvey","year":"2012"},{"key":"10.1016\/j.jep.2025.120314_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2024.102299","article-title":"The neuroprotective effects of Ferulic acid in toxin-induced models of Parkinson's disease: a review","volume":"97","author":"Hassani","year":"2024","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.jep.2025.120314_bib26","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.nrl.2015.06.011","article-title":"The 6-hydroxydopamine model and parkinsonian pathophysiology: novel findings in an older model","volume":"32","author":"Hernandez-Baltazar","year":"2017","journal-title":"Neurologia"},{"key":"10.1016\/j.jep.2025.120314_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.115215","article-title":"Kaempferol, a potential neuroprotective agent in neurodegenerative diseases: from chemistry to medicine","volume":"165","author":"Jin","year":"2023","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2025.120314_bib28","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.tips.2013.12.002","article-title":"Zebrafish as an emerging model for studying complex brain disorders","volume":"35","author":"Kalueff","year":"2014","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.jep.2025.120314_bib29","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.sajb.2016.06.009","article-title":"Sceletium tortuosum demonstrates in vitro anti-HIV and free radical scavenging activity","volume":"106","author":"Kapewangolo","year":"2016","journal-title":"South Afr. J. Bot."},{"key":"10.1016\/j.jep.2025.120314_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpc.2020.108893","article-title":"Naringenin alleviates 6-hydroxydopamine induced Parkinsonism in SHSY5Y cells and zebrafish model","volume":"239","author":"Kesh","year":"2021","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib31","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jep.2016.12.004","article-title":"Mesembrine alkaloids: review of their occurrence, chemistry, and pharmacology","volume":"195","author":"Krstenansky","year":"2017","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib32","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.chemosphere.2018.01.045","article-title":"Novel procedures for whole organism detection and quantification of fluorescence as a measurement for oxidative stress in zebrafish (Danio rerio) larvae","volume":"197","author":"Lackmann","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.jep.2025.120314_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2024.176819","article-title":"Experimental models of Parkinson's disease: challenges and opportunities","volume":"980","author":"Lal","year":"2024","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib34","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1056\/NEJM199810153391607","article-title":"Parkinson's disease","volume":"339","author":"Lang","year":"1998","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jep.2025.120314_bib35","first-page":"151","article-title":"Sceletium tortuosum: effects on central nervous system and related disease","volume":"10","author":"Luo","year":"2020","journal-title":"J. Pharmaceut. Biomed. Sci."},{"key":"10.1016\/j.jep.2025.120314_bib36","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0273583","article-title":"A network pharmacology-based approach to explore the therapeutic potential of Sceletium tortuosum in the treatment of neurodegenerative disorders","volume":"17","author":"Luo","year":"2022","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2025.120314_bib37","doi-asserted-by":"crossref","first-page":"3263","DOI":"10.1096\/fj.08-125443","article-title":"Glutathione\u2014a review on its role and significance in Parkinson's disease","volume":"23","author":"Martin","year":"2009","journal-title":"FASEB J."},{"key":"10.1016\/j.jep.2025.120314_bib38","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.fct.2014.09.017","article-title":"A toxicological safety assessment of a standardized extract of Sceletium tortuosum (Zembrin\u00ae) in rats","volume":"74","author":"Murbach","year":"2014","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jep.2025.120314_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ncl.2014.09.010","article-title":"Pathogenic mechanisms of neurodegeneration in Parkinson disease","volume":"33","author":"Mullin","year":"2015","journal-title":"Neurol. Clin."},{"key":"10.1016\/j.jep.2025.120314_bib40","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1089\/acm.2012.0185","article-title":"A randomized, double-blind, parallel-group, placebo-controlled trial of Extract Sceletium tortuosum (Zembrin) in healthy adults","volume":"19","author":"Nell","year":"2013","journal-title":"J. Alternative Compl. Med."},{"key":"10.1016\/j.jep.2025.120314_bib41","article-title":"Role of free radical and antioxidant imbalance in pathogenesis of Parkinson's disease","volume":"20","author":"Nikam","year":"2009","journal-title":"Biomed. Res."},{"key":"10.1016\/j.jep.2025.120314_bib42","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1212\/WNL.0b013e3181a1d44c","article-title":"The scientific and clinical basis for the treatment of Parkinson disease","volume":"72","author":"Olanow","year":"2009","journal-title":"Neurology"},{"key":"10.1016\/j.jep.2025.120314_bib43","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.vascn.2006.04.004","article-title":"Neurotoxicity assessment using zebrafish","volume":"55","author":"Parng","year":"2007","journal-title":"J. Pharmacol. Toxicol. Methods"},{"key":"10.1016\/j.jep.2025.120314_bib44","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.jep.2008.10.008","article-title":"Investigations of the phytochemical content of Sceletium tortuosum following the preparation of \u201cKougoed\u201d by fermentation of plant material","volume":"121","author":"Patnala","year":"2009","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib46","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0165-3806(02)00354-1","article-title":"Development of the catecholaminergic system in the early zebrafish brain: an immunohistochemical study","volume":"137","author":"Rink","year":"2002","journal-title":"Dev. Brain Res."},{"key":"10.1016\/j.jep.2025.120314_bib48","doi-asserted-by":"crossref","first-page":"81112","DOI":"10.1007\/s11356-022-23337-6","article-title":"Extraction and characterization of phenolic compounds and their potential antioxidant activities","volume":"29","author":"Shi","year":"2022","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.jep.2025.120314_bib49","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.bse.2012.06.025","article-title":"The chemotypic variation of Sceletium tortuosum alkaloids and commercial product formulations","volume":"44","author":"Shikanga","year":"2012","journal-title":"Biochem. Systemat. Ecol."},{"key":"10.1016\/j.jep.2025.120314_bib50","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1055\/s-0031-1280367","article-title":"In vitro permeation of mesembrine alkaloids from Sceletium tortuosum across porcine buccal, sublingual, and intestinal mucosa","volume":"78","author":"Shikanga","year":"2012","journal-title":"Planta Med."},{"key":"10.1016\/j.jep.2025.120314_bib51","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0378-8741(95)01342-3","article-title":"Psychoactive constituents of the genus Sceletium NE Br. and other Mesembryanthemaceae: a review","volume":"50","author":"Smith","year":"1996","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib52","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.jep.2008.08.010","article-title":"Review on plants with CNS-effects used in traditional South African medicine against mental diseases","volume":"119","author":"Stafford","year":"2008","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib53","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jep.2015.11.033","article-title":"Modulation of glucocorticoid, mineralocorticoid and androgen production in H295 cells by Trimesemine\u2122, a mesembrine-rich Sceletium extract","volume":"177","author":"Swart","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120314_bib54","doi-asserted-by":"crossref","first-page":"2708","DOI":"10.1038\/npp.2013.183","article-title":"Acute effects of Sceletium tortuosum (Zembrin), a dual 5-HT reuptake and PDE4 inhibitor, in the human amygdala and its connection to the hypothalamus","volume":"38","author":"Terburg","year":"2013","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jep.2025.120314_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.pbb.2019.172828","article-title":"Identification of antiparkinsonian drugs in the 6-hydroxydopamine zebrafish model","volume":"189","author":"Vaz","year":"2020","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.jep.2025.120314_bib56","series-title":"The Zebrafish Book; A Guide for the Laboratory Use of Zebrafish (Danio rerio)","author":"Westerfield","year":"2007"},{"key":"10.1016\/j.jep.2025.120314_bib57","first-page":"1","article-title":"Fucoxanthin prevents 6-OHDA-induced neurotoxicity by targeting Keap1","author":"Wu","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.jep.2025.120314_bib58","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1212\/CON.0000000000000764","article-title":"Parkinson disease","volume":"25","author":"Zesiewicz","year":"2019","journal-title":"Continuum: Lifelong Learning Neurol."},{"key":"10.1016\/j.jep.2025.120314_bib59","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jep.2015.04.040","article-title":"Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS\/NO and AKT\/GSK3\u03b2 pathways","volume":"170","author":"Zhang","year":"2015","journal-title":"J. Ethnopharmacol."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874125010062?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874125010062?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T17:47:40Z","timestamp":1777571260000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874125010062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":57,"alternative-id":["S0378874125010062"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2025.120314","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuroprotective and neurorestorative properties of Mesembryanthemum tortuosum in a Parkinson's disease zebrafish larvae model","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2025.120314","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"120314"}}