{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:52:51Z","timestamp":1791910371967,"version":"4.3.4"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2017YFC1702200"],"award-info":[{"award-number":["2017YFC1702200"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2017YFC1702202"],"award-info":[{"award-number":["2017YFC1702202"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82274134"],"award-info":[{"award-number":["82274134"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022963","name":"Key Research and Development Program of Zhejiang Province","doi-asserted-by":"publisher","award":["2024C03104,2025C02183"],"award-info":[{"award-number":["2024C03104,2025C02183"]}],"id":[{"id":"10.13039\/100022963","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.jep.2025.120668","type":"journal-article","created":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T00:35:59Z","timestamp":1759538159000},"page":"120668","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"PB","title":["Network pharmacology and experimental validation uncover how Shoutai pills improve ovarian function in postpartum depression following a secondary birth"],"prefix":"10.1016","volume":"355","author":[{"given":"Cheng-Liang","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Mei","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Piao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Yuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun-Xia","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan-Feng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng-Qiang","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gui-Yuan","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su-Hong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2025.120668_bib1","author":"Acupuncture"},{"issue":"2","key":"10.1016\/j.jep.2025.120668_bib2","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/(SICI)1099-1573(199603)10:2<117::AID-PTR782>3.0.CO;2-X","article-title":"Pharmacological study of Cuscuta campestris yuncker","volume":"10","author":"Agha","year":"1996","journal-title":"Phytother Res."},{"issue":"1","key":"10.1016\/j.jep.2025.120668_bib3","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1471-2202-10-59","article-title":"Nongenomic mechanisms of physiological estrogen-mediated dopamine efflux","volume":"10","author":"Alyea","year":"2009","journal-title":"BMC Neurosci."},{"issue":"3","key":"10.1016\/j.jep.2025.120668_bib4","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/S0010-440X(03)00034-8","article-title":"Endocrine factors in the etiology of postpartum depression","volume":"44","author":"Bloch","year":"2003","journal-title":"Compr. Psychiatry"},{"issue":"7","key":"10.1016\/j.jep.2025.120668_bib5","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1083\/jcb.201504092","article-title":"A novel form of synaptic plasticity in field CA3 of hippocampus requires GPER1 activation and BDNF release","volume":"210","author":"Briz","year":"2015","journal-title":"J. Cell Biol."},{"issue":"1","key":"10.1016\/j.jep.2025.120668_bib6","doi-asserted-by":"crossref","first-page":"e35","DOI":"10.1016\/S2468-2667(23)00268-2","article-title":"Effectiveness of two systems-level interventions to address perinatal depression in obstetric settings (PRISM): an active-controlled cluster-randomised trial","volume":"9","author":"Byatt","year":"2024","journal-title":"Lancet Public Health"},{"issue":"20","key":"10.1016\/j.jep.2025.120668_bib7","doi-asserted-by":"crossref","first-page":"3700","DOI":"10.3390\/molecules24203700","article-title":"PI3K\u2013AKT signaling activation and icariin: the potential effects on the perimenopausal depression-like rat model","volume":"24","author":"Cao","year":"2019","journal-title":"Molecules"},{"issue":"3","key":"10.1016\/j.jep.2025.120668_bib8","doi-asserted-by":"crossref","first-page":"314.e311","DOI":"10.1016\/j.ajog.2016.01.170","article-title":"The effect of antidepressants on fertility","volume":"215","author":"Casilla Lennon","year":"2016","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.jep.2025.120668_bib9","article-title":"Antidepressant potential of quercetin and its glycoside derivatives: a comprehensive review and update","volume":"13","author":"Chen","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"2","key":"10.1016\/j.jep.2025.120668_bib10","doi-asserted-by":"crossref","DOI":"10.1093\/ijnp\/pyae010","article-title":"PI3K-AKT\/mTOR signaling in psychiatric disorders: a valuable target to stimulate or suppress?","volume":"27","author":"Chen","year":"2024","journal-title":"Int. J. Neuropsychopharmacol."},{"issue":"12","key":"10.1016\/j.jep.2025.120668_bib11","doi-asserted-by":"crossref","first-page":"5855","DOI":"10.1210\/endo.140.12.7222","article-title":"Prevention of the polycystic ovarian phenotype and characterization of ovulatory capacity in the estrogen receptor-alpha knockout mouse","volume":"140","author":"Couse","year":"1999","journal-title":"Endocrinology"},{"issue":"6","key":"10.1016\/j.jep.2025.120668_bib12","article-title":"Expert consensus on guidelines for prevention and treatment of postpartum depression (for obstetricians and community physicians)","volume":"15","author":"Ding","year":"2014","journal-title":"Chin. J. Clin. Obstet. Gynecol."},{"key":"10.1016\/j.jep.2025.120668_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155816","article-title":"Beneficial effects of Dendrobium officinale national herbal drink on metabolic immune crosstalk via regulate SCFAs-Th17\/Treg","volume":"132","author":"Dong","year":"2024","journal-title":"Phytomedicine"},{"issue":"12","key":"10.1016\/j.jep.2025.120668_bib14","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1021\/acsptsci.3c00226","article-title":"Therapeutic potential of kaempferol against sleep deprivation-induced cognitive impairment: modulation of neuroinflammation and synaptic plasticity disruption in mice","volume":"6","author":"Du","year":"2023","journal-title":"ACS Pharmacol. Transl. Sci."},{"key":"10.1016\/j.jep.2025.120668_bib15","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.666502","article-title":"Enhancement of Insulin\/PI3K\/Akt signaling pathway and modulation of gut microbiome by probiotics fermentation technology, a kefir grain product, in sporadic alzheimer's disease model in mice","volume":"12","author":"El Sayed","year":"2021","journal-title":"Front. Pharmacol."},{"issue":"4","key":"10.1016\/j.jep.2025.120668_bib16","doi-asserted-by":"crossref","first-page":"3257","DOI":"10.3390\/ijerph20043257","article-title":"The involvement of prolactin in stress-related disorders","volume":"20","author":"Faron-G\u00f3recka","year":"2023","journal-title":"Int. J. Environ. Res. Publ. Health"},{"issue":"5","key":"10.1016\/j.jep.2025.120668_bib17","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.joim.2020.06.002","article-title":"Lavender and dodder combined herbal syrup versus citalopram in major depressive disorder with anxious distress: a double-blind randomized trial","volume":"18","author":"Firoozeei","year":"2020","journal-title":"J. Integr. Med."},{"issue":"6","key":"10.1016\/j.jep.2025.120668_bib18","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s11920-002-0074-x","article-title":"Etiology and treatment of postpartum depression","volume":"4","author":"Flores","year":"2002","journal-title":"Curr. Psychiatry Rep."},{"issue":"1","key":"10.1016\/j.jep.2025.120668_bib19","doi-asserted-by":"crossref","first-page":"60","DOI":"10.4103\/jehp.jehp_9_16","article-title":"Postpartum depression risk factors: a narrative review","volume":"6","author":"Ghaedrahmati","year":"2017","journal-title":"J. Educ. Health Promot."},{"issue":"3","key":"10.1016\/j.jep.2025.120668_bib20","first-page":"10","article-title":"Clinical efficacy of shoutai pills modified in treating threatened abortion (kidney deficiency type) and its effects on sex hormone levels","volume":"44","author":"He","year":"2022","journal-title":"Hubei J. Tradit. Chin. Med."},{"issue":"3","key":"10.1016\/j.jep.2025.120668_bib21","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0014-5793(01)02353-5","article-title":"Akt mediates insulin induction of glucose uptake and up-regulation of GLUT4 gene expression in brown adipocytes","volume":"494","author":"Hernandez","year":"2001","journal-title":"FEBS Lett."},{"key":"10.1016\/j.jep.2025.120668_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.117025","article-title":"Chinese herbal medicine alleviates autophagy and apoptosis in ovarian granulosa cells induced by testosterone through PI3K\/AKT1\/FOXO1 pathway","volume":"318","author":"Hu","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120668_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.120057","article-title":"Integrating network pharmacology and transcriptomics reveals that bushen huoxue recipe ameliorates ferroptosis and apoptosis in granulosa cells by regulating PI3K\/Akt signaling pathway in premature ovarian insufficiency mice","volume":"351","author":"Huang","year":"2025","journal-title":"J. Ethnopharmacol."},{"issue":"8","key":"10.1016\/j.jep.2025.120668_bib24","article-title":"Phytochemical, free radical scavenging and antifungal profile of Cuscuta campestris yunck","volume":"15","author":"Jakovljevi\u0107","year":"2018","journal-title":"Seeds. CHEM BIODIVERS."},{"issue":"3","key":"10.1016\/j.jep.2025.120668_bib25","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1177\/1099800406294598","article-title":"Dysregulation of the hypothalamic-pituitary-adrenal axis in postpartum depression","volume":"8","author":"Jolley","year":"2007","journal-title":"Biol. Res. Nurs."},{"key":"10.1016\/j.jep.2025.120668_bib26","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3389\/fendo.2013.00012","article-title":"Regulation of gonadotropins by corticotropin-releasing factor and urocortin","volume":"4","author":"Kageyama","year":"2013","journal-title":"Front. Endocrinol."},{"issue":"3","key":"10.1016\/j.jep.2025.120668_bib27","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1177\/0748233713504810","article-title":"Neuroprotective effect of quercetin against oxidative damage and neuronal apoptosis caused by cadmium in hippocampus","volume":"32","author":"Kanter","year":"2016","journal-title":"Toxicol. Ind. Health"},{"issue":"3","key":"10.1016\/j.jep.2025.120668_bib28","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1210\/endo.138.3.4979","article-title":"Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta","volume":"138","author":"Kuiper","year":"1997","journal-title":"Endocrinology"},{"issue":"10","key":"10.1016\/j.jep.2025.120668_bib29","doi-asserted-by":"crossref","first-page":"4252","DOI":"10.1210\/endo.139.10.6216","article-title":"Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor \u03b2","volume":"139","author":"Kuiper","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.jep.2025.120668_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.156208","article-title":"Salidroside facilitates neuroprotective effects in ischemic stroke by promoting axonal sprouting through promoting autophagy","volume":"135","author":"Lai","year":"2024","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.jep.2025.120668_bib31","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1210\/en.2007-0372","article-title":"Estradiol regulates corticotropin-releasing hormone gene (Crh) expression in a rapid and phasic manner that parallels estrogen Receptor-\u03b1 and -\u03b2 recruitment to a 3\u2032,5\u2032-Cyclic adenosine 5\u2032-Monophosphate regulatory region of the proximal crh promoter","volume":"149","author":"Lalmansingh","year":"2008","journal-title":"Endocrinology"},{"issue":"4","key":"10.1016\/j.jep.2025.120668_bib32","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/j.bbrc.2005.08.256","article-title":"Up-regulation of PI3K\/Akt signaling by 17\u03b2-estradiol through activation of estrogen receptor-\u03b1, but not estrogen receptor-\u03b2, and stimulates cell growth in breast cancer cells","volume":"336","author":"Lee","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"12","key":"10.1016\/j.jep.2025.120668_bib33","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1016\/j.procbio.2011.09.003","article-title":"Quercetin is increased in heat-processed Cuscuta campestris seeds, which enhances the seed's anti-inflammatory and anti-proliferative activities","volume":"46","author":"Lee","year":"2011","journal-title":"Process Biochem"},{"issue":"15","key":"10.1016\/j.jep.2025.120668_bib34","first-page":"2715","article-title":"Advances in diagnosis and treatment of puerperal depression by traditional Chinese and Western medicine","volume":"37","author":"Li","year":"2022","journal-title":"Chung-kuo Fu Yu Pao Chien"},{"issue":"6","key":"10.1016\/j.jep.2025.120668_bib35","first-page":"1139","article-title":"Effect of sleep deprivation on the metabolism of hippocampal amino acids and monoamine neurotransmitters in mice and their behaviors","volume":"54","author":"Liang","year":"2023","journal-title":"J. Sichuan Univ."},{"issue":"1","key":"10.1016\/j.jep.2025.120668_bib36","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s12974-025-03374-x","article-title":"PARP9 exacerbates apoptosis and neuroinflammation via the PI3K pathway in the thalamus and hippocampus and cognitive decline after cortical infarction","volume":"22","author":"Liao","year":"2025","journal-title":"J. Neuroinflammation"},{"issue":"10","key":"10.1016\/j.jep.2025.120668_bib37","article-title":"Advances in the diagnosis and treatment of postpartum depression: perspectives from traditional Chinese medicine and Western medicine","volume":"23","author":"Liu","year":"2017","journal-title":"J. Basic Chin. Med."},{"issue":"12","key":"10.1016\/j.jep.2025.120668_bib38","first-page":"3397","article-title":"Ovulatory disorders under \"common therapeutic principle for different diseases\": essence of \"Tiangui\" and relationship with ovulation disorders","volume":"47","author":"Liu","year":"2022","journal-title":"China J. Chin. Mater. Med."},{"issue":"1","key":"10.1016\/j.jep.2025.120668_bib39","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1515\/biol-2021-0014","article-title":"Quercetin inhibits cytotoxicity of PC12 cells induced by amyloid-beta 25\u201335 via stimulating estrogen receptor \u03b1, activating ERK1\/2, and inhibiting apoptosis","volume":"17","author":"Liu","year":"2022","journal-title":"Open Life Sci."},{"issue":"3","key":"10.1016\/j.jep.2025.120668_bib40","first-page":"621","article-title":"Therapeutic effect of modified shoutai pills on polycystic ovary syndrome with recurrent spontaneous abortion: a clinical observation","volume":"42","author":"Luo","year":"2025","journal-title":"J. Guangzhou Univ. Tradit. Chin. Med."},{"issue":"3","key":"10.1016\/j.jep.2025.120668_bib41","first-page":"333","article-title":"Analysis of postpartum depression and its influencing factors in parturient with a second child","volume":"32","author":"Ma","year":"2021","journal-title":"Chin. J. Woman Child Health Res."},{"issue":"9","key":"10.1016\/j.jep.2025.120668_bib42","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.5664\/jcsm.7924","article-title":"Poor postpartum sleep quality predicts subsequent postpartum depressive symptoms in a high-risk sample","volume":"15","author":"McEvoy","year":"2019","journal-title":"J. Clin. Sleep Med."},{"issue":"6","key":"10.1016\/j.jep.2025.120668_bib43","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1152\/jappl.2001.91.6.2785","article-title":"Invited review: estrogens effects on the brain: multiple sites and molecular mechanisms","volume":"91","author":"McEwen","year":"2001","journal-title":"J. Appl. Physiol."},{"issue":"11","key":"10.1016\/j.jep.2025.120668_bib44","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1017\/S0033291713003231","article-title":"Early predictive biomarkers for postpartum depression point to a role for estrogen receptor signaling","volume":"44","author":"Mehta","year":"2014","journal-title":"Psychol. Med."},{"key":"10.1016\/j.jep.2025.120668_bib45","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.physbeh.2017.01.006","article-title":"Quercetin prevents chronic unpredictable stress induced behavioral dysfunction in mice by alleviating hippocampal oxidative and inflammatory stress","volume":"171","author":"Mehta","year":"2017","journal-title":"Physiol. Behav."},{"issue":"4","key":"10.1016\/j.jep.2025.120668_bib46","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s11064-025-04447-2","article-title":"Assessment of the therapeutic potential of Hesperidin and quercetin nanoparticles on oxidative stress, enzyme activities, trophic factors, and monoamines in an animal model of depression","volume":"50","author":"Mohammed","year":"2025","journal-title":"Neurochem. Res."},{"issue":"2","key":"10.1016\/j.jep.2025.120668_bib47","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.neures.2005.06.008","article-title":"Chronic stress, as well as acute stress, reduces BDNF mRNA expression in the rat hippocampus but less robustly","volume":"53","author":"Murakami","year":"2005","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.jep.2025.120668_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1410942","article-title":"Network pharmacology: an efficient but underutilized approach in oral, head and neck cancer Therapy\u2014A review","author":"Muthuramalingam","year":"2024","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.jep.2025.120668_bib49","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1093\/emph\/eow003","article-title":"Postnatal depression and reproductive success in modern, low-fertility contexts","volume":"2016","author":"Myers","year":"2016","journal-title":"EVOL MED PUBLIC HLTH"},{"issue":"7","key":"10.1016\/j.jep.2025.120668_bib50","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s11920-016-0705-2","article-title":"Disturbed sleep and postpartum depression","volume":"18","author":"Okun","year":"2016","journal-title":"Curr. Psychiatry Rep."},{"issue":"8","key":"10.1016\/j.jep.2025.120668_bib51","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1097\/PSY.0000000000001234","article-title":"Postpartum insomnia and poor sleep quality are longitudinally predictive of postpartum mood symptoms","volume":"85","author":"Okun","year":"2023","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.jep.2025.120668_bib52","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.eurpsy.2016.11.009","article-title":"Positive screening and risk factors for postpartum depression","volume":"42","author":"Palumbo","year":"2017","journal-title":"EUR PSYCHIAT"},{"issue":"12","key":"10.1016\/j.jep.2025.120668_bib53","first-page":"4835","article-title":"Immunocytochemical localization of estrogen receptors \u03b1 and \u03b2 in the human reproductive organs","volume":"85","author":"Pelletier","year":"2000","journal-title":"J Clin Endocr Metab."},{"issue":"6","key":"10.1016\/j.jep.2025.120668_bib54","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s00737-013-0373-8","article-title":"Association study of the estrogen receptor gene ESR1 with postpartum depression--a pilot study","volume":"16","author":"Pinsonneault","year":"2013","journal-title":"Arch Womens Ment Health"},{"issue":"7","key":"10.1016\/j.jep.2025.120668_bib55","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/j.bcp.2003.11.009","article-title":"Stimulatory effect of naturally occurring flavonols quercetin and kaempferol on alkaline phosphatase activity in MG-63 human osteoblasts through ERK and estrogen receptor pathway","volume":"67","author":"Prouillet","year":"2004","journal-title":"Biochem. Pharmacol."},{"issue":"1","key":"10.1016\/j.jep.2025.120668_bib56","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1186\/s13020-024-00939-5","article-title":"The effect of modified qiyuan paste on mice with low immunity and sleep deprivation by regulating GABA nerve and immune system","volume":"19","author":"Rong","year":"2024","journal-title":"CHIN MED-UK"},{"issue":"3","key":"10.1016\/j.jep.2025.120668_bib57","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1002\/mrd.23107","article-title":"Kaempferol promotes primordial follicle activation through the phosphatidylinositol 3-kinase\/protein kinase B signaling pathway and reduces DNA fragmentation of sheep preantral follicles cultured in vitro","volume":"86","author":"Santos","year":"2019","journal-title":"Mol. Reprod. Dev."},{"issue":"2","key":"10.1016\/j.jep.2025.120668_bib58","first-page":"221","article-title":"Exploration of the theories: \"heart Governs Spirit\"","volume":"18","author":"Shi","year":"2023","journal-title":"\"Brain as the Residence of Primordial Spirit\", and \"Heart - Brain Joint Governance of Spirit\""},{"key":"10.1016\/j.jep.2025.120668_bib59","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1146\/annurev-med-041217-011106","article-title":"Postpartum depression: pathophysiology, treatment, and emerging therapeutics","volume":"70","author":"Stewart","year":"2019","journal-title":"Annu. Rev. Med."},{"key":"10.1016\/j.jep.2025.120668_bib60","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.phymed.2017.10.005","article-title":"A double-blind, randomized, placebo-controlled trial of saffron Stigma (crocus sativus L.) in mothers suffering from mild-to-moderate postpartum depression","volume":"36","author":"Tabeshpour","year":"2017","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.jep.2025.120668_bib61","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/s41398-021-01663-6","article-title":"Mapping global prevalence of depression among postpartum women","volume":"11","author":"Wang","year":"2021","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.jep.2025.120668_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.156991","article-title":"Shoutai pill exhibits anti-miscarriage efficacy through tripartite modulation of gut microbiota, systemic metabolism, and maternal-fetal immunity: a multi-omics analysis","volume":"145","author":"Xu","year":"2025","journal-title":"Phytomedicine"},{"issue":"7","key":"10.1016\/j.jep.2025.120668_bib63","first-page":"39","article-title":"Study on the effect and mechanism of Ganoderma lucidum spore oil in alleviating physical fatigue in mice","volume":"50","author":"Yu","year":"2024","journal-title":"Food Ferment. Ind."},{"key":"10.1016\/j.jep.2025.120668_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.113156","article-title":"Systematic biological and proteomics strategies to explore the regulation mechanism of shoutai wan on recurrent spontaneous Abortion's biological network","volume":"263","author":"Zeng","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120668_bib65","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.bbrc.2022.09.088","article-title":"Quercetin ameliorates memory impairment by inhibiting abnormal microglial activation in a mouse model of paradoxical sleep deprivation","volume":"632","author":"Zhang","year":"2022","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jep.2025.120668_bib66","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116502","article-title":"Shoutai wan regulates glycolysis imbalance at the maternal-fetal interface in threatened abortion mice","volume":"312","author":"Zhang","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120668_bib67","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.135844","article-title":"Cordyceps polysaccharide improves polycystic ovary syndrome by inhibiting gut-derived LPS\/TLR4 pathway to attenuates insulin resistance","volume":"280","author":"Zhang","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jep.2025.120668_bib68","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.116253","article-title":"Cuscuta chinensis flavonoids alleviate ovarian damage in offspring female mice induced by BPA exposure during pregnancy by regulating the central carbon metabolism pathway","volume":"275","author":"Zhao","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"2","key":"10.1016\/j.jep.2025.120668_bib69","doi-asserted-by":"crossref","first-page":"175","DOI":"10.5534\/wjmh.180069","article-title":"Traditional Chinese medicine as a remedy for Male infertility: a review","volume":"37","author":"Zhou","year":"2019","journal-title":"WORLD J MENS HEALTH"},{"issue":"1","key":"10.1016\/j.jep.2025.120668_bib70","article-title":"Quercetin alleviates the progression of breast cancer-related depression via inhibiting the pyroptosis and promoting the immune response","volume":"2022","author":"Zhu","year":"2022","journal-title":"Mediat. Inflamm."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874125013601?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874125013601?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T03:32:26Z","timestamp":1764041546000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874125013601"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":70,"alternative-id":["S0378874125013601"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2025.120668","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Network pharmacology and experimental validation uncover how Shoutai pills improve ovarian function in postpartum depression following a secondary birth","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2025.120668","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"120668"}}