{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T13:00:18Z","timestamp":1792501218850,"version":"4.5.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2025A1515010171"],"award-info":[{"award-number":["2025A1515010171"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004000","name":"Guangzhou Municipal Science and Technology Program key projects","doi-asserted-by":"publisher","award":["2025A04J5152"],"award-info":[{"award-number":["2025A04J5152"]}],"id":[{"id":"10.13039\/501100004000","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010256","name":"Guangzhou Municipal Science and Technology Project","doi-asserted-by":"publisher","award":["202102070001"],"award-info":[{"award-number":["202102070001"]}],"id":[{"id":"10.13039\/501100010256","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013066","name":"Key Scientific Research Project of Colleges and Universities in Henan Province","doi-asserted-by":"publisher","award":["24A360022"],"award-info":[{"award-number":["24A360022"]}],"id":[{"id":"10.13039\/501100013066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82204582"],"award-info":[{"award-number":["82204582"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.jep.2025.120935","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T14:00:21Z","timestamp":1763647221000},"page":"120935","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Transcriptomic, artificial neural network and Chou-Talalay analysis based investigation of potential mechanism and active components of Qi-Lin pill in treating diminished ovarian reserve"],"prefix":"10.1016","volume":"357","author":[{"given":"Xi-yang","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing-chang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lv-qi","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cai-lian","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2025.120935_bib1","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2019.00305","article-title":"Molecular mechanisms of action of FSH","volume":"10","author":"Casarini","year":"2019","journal-title":"Front. Endocrinol."},{"issue":"2","key":"10.1016\/j.jep.2025.120935_bib2","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1158\/0008-5472.CAN-09-1947","article-title":"Drug combination studies and their synergy quantification using the chou-talalay method","volume":"70","author":"Chou","year":"2010","journal-title":"Cancer Res."},{"issue":"6","key":"10.1016\/j.jep.2025.120935_bib3","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1177\/0192623315570339","article-title":"Vaginal cytology of the laboratory rat and mouse: review and criteria for the staging of the estrous cycle using stained vaginal smears","volume":"43","author":"Cora","year":"2015","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.jep.2025.120935_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.117782","article-title":"Zishen yutai pills restore fertility in premature ovarian failure through regulating arachidonic acid metabolism and the ATK pathway","volume":"324","author":"Dang","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120935_bib5","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1130681","article-title":"Androgen receptor signaling regulates follicular growth and steroidogenesis in interaction with gonadotropins in the ovary during mini-puberty in mice","volume":"14","author":"Devillers","year":"2023","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.jep.2025.120935_bib6","article-title":"17\u03b2-estradiol improves the developmental ability, inhibits reactive oxygen species levels and apoptosis of porcine oocytes by regulating autophagy events","volume":"209","author":"Duan","year":"2021","journal-title":"J. Steroid Biochem."},{"issue":"6","key":"10.1016\/j.jep.2025.120935_bib7","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1007\/s10815-019-01446-5","article-title":"Apoptosis of mural granulosa cells is increased in women with diminished ovarian reserve","volume":"36","author":"Fan","year":"2019","journal-title":"J. Assist. Reprod. Genet."},{"issue":"5","key":"10.1016\/j.jep.2025.120935_bib8","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.fertnstert.2023.07.024","article-title":"Oral follicle-stimulating hormone receptor agonist affects granulosa cells differently than recombinant human FSH","volume":"120","author":"Guner","year":"2023","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jep.2025.120935_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2019.112228","article-title":"Identification and quantification of the quality markers and anti-migraine active components in chuanxiong rhizoma and cyperi rhizoma herbal pair based on chemometric analysis between chemical constituents and pharmacological effects","volume":"246","author":"Guo","year":"2020","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.jep.2025.120935_bib10","doi-asserted-by":"crossref","first-page":"2610","DOI":"10.1096\/fj.201801401R","article-title":"Mdm2-p53-SF1 pathway in ovarian granulosa cells directs ovulation and fertilization by conditioning oocyte quality","volume":"33","author":"Haraguchi","year":"2019","journal-title":"FASEB J."},{"issue":"4","key":"10.1016\/j.jep.2025.120935_bib11","first-page":"1361","article-title":"Expression of serotonin receptors 5-HT1A, 5-HT1B, 5-HT2B and 5-HT4 in ovary and in ovarian tumours","volume":"32","author":"Henriksen","year":"2012","journal-title":"Anticancer Res."},{"issue":"7","key":"10.1016\/j.jep.2025.120935_bib12","first-page":"182","article-title":"Clinical study of 30 cases for Qi-Lin pill in treatment of diminished ovarian reserve","volume":"47","author":"Huang","year":"2015","journal-title":"New. J. Tradit. Chin. Med."},{"issue":"47","key":"10.1016\/j.jep.2025.120935_bib13","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000017841","article-title":"Traditional Chinese herb for low endometrial receptivity and its effect on pregnancy protocol for a systematic review and meta-analysis","volume":"98","author":"Jiang","year":"2019","journal-title":"Medicine"},{"issue":"10","key":"10.1016\/j.jep.2025.120935_bib14","doi-asserted-by":"crossref","DOI":"10.3390\/ijms17101635","article-title":"Interactions between two different G protein-coupled receptors in reproductive hormone-producing cells: the role of PACAP and its receptor PAC1R","volume":"17","author":"Kanasaki","year":"2016","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.jep.2025.120935_bib15","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/asj.12283","article-title":"Effect of estradiol-17\u03b2 during growth culture on the growth, maturation, cumulus expansion and development of porcine oocytes from early antral follicles","volume":"86","author":"Kubo","year":"2015","journal-title":"Anim. Sci. J."},{"issue":"3","key":"10.1016\/j.jep.2025.120935_bib16","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1007\/s10815-022-02422-2","article-title":"Expression of pro-apoptotic and anti-apoptotic proteins in granulosa cells of women with diminished ovarian reserve","volume":"39","author":"Kuran","year":"2022","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.jep.2025.120935_bib17","doi-asserted-by":"crossref","first-page":"3331","DOI":"10.2147\/DDDT.S321010","article-title":"Qilin pill exerts therapeutic effect on resection-induced premature ovarian insufficiency rats by inhibiting the MAPK and PI3K-AKT signaling pathways","volume":"15","author":"Li","year":"2021","journal-title":"Drug Des. Dev. Ther."},{"issue":"3","key":"10.1016\/j.jep.2025.120935_bib18","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.7150\/ijbs.68028","article-title":"Mir-484 contributes to diminished ovarian reserve by regulating granulosa cell function via YAP1-mediated mitochondrial function and apoptosis","volume":"18","author":"Li","year":"2022","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.jep.2025.120935_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2022.115157","article-title":"Simultaneous determination of multiple constituents of Qi-Lin pill by UPLC-MS\/MS: applications to pharmacokinetics and testicular tissue distribution in rats","volume":"223","author":"Li","year":"2023","journal-title":"J Pharmaceut Biomed"},{"key":"10.1016\/j.jep.2025.120935_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2023.1276310","article-title":"Research progress on the premature ovarian failure caused by cisplatin therapy","volume":"13","author":"Li","year":"2023","journal-title":"Front. Oncol."},{"issue":"24","key":"10.1016\/j.jep.2025.120935_bib21","first-page":"2107","article-title":"A multi-centered randomized single-blind controlled clinical trial of Qi-Lin pills in the treatment of 60 diminished ovarian reserve patients with irregular menstruation","volume":"60","author":"Liao","year":"2019","journal-title":"J. Tradit. Chin. Med."},{"issue":"1","key":"10.1016\/j.jep.2025.120935_bib22","first-page":"183","article-title":"Study on the repair effect of qilin pills on ovarian granulosa cell damage","volume":"40","author":"Liu","year":"2023","journal-title":"Journal of Guangzhou University of Traditional Chinese Medicine"},{"key":"10.1016\/j.jep.2025.120935_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.113789","article-title":"Zihuai recipe alleviates cyclophosphamide-induced diminished ovarian reserve via suppressing PI3K\/AKT-mediated apoptosis","volume":"277","author":"Liu","year":"2021","journal-title":"J. Ethnopharmacol."},{"issue":"3","key":"10.1016\/j.jep.2025.120935_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.103414","article-title":"Effects of exogenous energy on synthesis of steroid hormones and expression characteristics of the CREB\/StAR signaling pathway in theca cells of laying hen","volume":"103","author":"Lu","year":"2024","journal-title":"Poult. Sci."},{"key":"10.1016\/j.jep.2025.120935_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.115278","article-title":"Maternal genetic intergenerational and transgenerational effects on hormone synthesis in ovarian granulosa cells of offspring exposed to cadmium during pregnancy","volume":"263","author":"Luo","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"12","key":"10.1016\/j.jep.2025.120935_bib26","doi-asserted-by":"crossref","DOI":"10.3390\/cancers16122288","article-title":"Gynotoxic effects of chemotherapy and potential protective mechanisms","volume":"16","author":"Markowska","year":"2024","journal-title":"Cancers"},{"issue":"3","key":"10.1016\/j.jep.2025.120935_bib27","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/S1472-6483(10)60347-1","article-title":"Differential actions of FSH and LH during folliculogenesis","volume":"15","author":"Palermo","year":"2007","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.jep.2025.120935_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2020.111082","article-title":"Sphingosine-1 phosphate induces cAMP\/PKA-independent phosphorylation of the cAMP response element-binding protein (CREB) in granulosa cells","volume":"520","author":"Paradiso","year":"2021","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.jep.2025.120935_bib29","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.cca.2014.07.029","article-title":"AMH: an ovarian reserve biomarker in assisted reproduction","volume":"437","author":"Peluso","year":"2014","journal-title":"Clin. Chim. Acta"},{"issue":"8","key":"10.1016\/j.jep.2025.120935_bib30","doi-asserted-by":"crossref","DOI":"10.1002\/pbc.30448","article-title":"Diminished ovarian reserve in adolescent cancer survivors treated with heavy metal chemotherapy","volume":"70","author":"Pruett","year":"2023","journal-title":"Pediatr. Blood Cancer"},{"issue":"1","key":"10.1016\/j.jep.2025.120935_bib31","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s10815-015-0615-y","article-title":"The Anti-Mullerian hormone (AMH) acts as a gatekeeper of ovarian steroidogenesis inhibiting the granulosa cell response to both FSH and LH","volume":"33","author":"Sacchi","year":"2016","journal-title":"J. Assist. Reprod. Genet."},{"issue":"1","key":"10.1016\/j.jep.2025.120935_bib32","doi-asserted-by":"crossref","DOI":"10.1186\/s13063-020-04502-z","article-title":"Efficacy and safety of dingkun pill for female infertility patients with low prognosis undergoing in vitro fertilization-embryo transfer: study protocol for a multicenter, double-blind, randomized, placebo-controlled trial","volume":"21","author":"Song","year":"2020","journal-title":"Trials"},{"issue":"1","key":"10.1016\/j.jep.2025.120935_bib33","doi-asserted-by":"crossref","DOI":"10.1186\/s12958-022-00906-5","article-title":"Signaling mechanisms and their regulation during in vivo or in vitro maturation of mammalian oocytes","volume":"20","author":"Straczynska","year":"2022","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"2","key":"10.1016\/j.jep.2025.120935_bib34","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.fertnstert.2010.11.054","article-title":"Antral follicle count in clinical practice: building the bridge from ovarian reserve to in vitro fertilization outcome","volume":"95","author":"Styer","year":"2011","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jep.2025.120935_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2020.113402","article-title":"Identification and characterization of chemical constituents in Qi-Lin pills and their metabolites in rat bio-samples after oral administration using ultra-high performance liquid chromatography with quadrupole time-of-flight mass spectrometry","volume":"188","author":"Tang","year":"2020","journal-title":"J Pharmaceut Biomed"},{"issue":"8","key":"10.1016\/j.jep.2025.120935_bib36","doi-asserted-by":"crossref","first-page":"3020","DOI":"10.1210\/en.2018-00452","article-title":"FSH receptor signaling: complexity of interactions and signal diversity","volume":"159","author":"Ulloa-Aguirre","year":"2018","journal-title":"Endocrinology"},{"key":"10.1016\/j.jep.2025.120935_bib37","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2025.1598998","article-title":"IVF\/ICSI treatment for patients with diminished ovarian reserve with or without kuntai capsule pretreatment: a retrospective cohort study stratified by a controlled ovarian stimulation regimen","volume":"16","author":"Wan","year":"2025","journal-title":"Front. Endocrinol."},{"issue":"24","key":"10.1016\/j.jep.2025.120935_bib38","doi-asserted-by":"crossref","DOI":"10.3390\/molecules28248123","article-title":"Paeoniflorin alleviates cisplatin-induced diminished ovarian reserve by restoring the function of ovarian granulosa cells via activating FSHR\/cAMP\/PKA\/CREB signaling pathway","volume":"28","author":"Wu","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2025.120935_bib39","article-title":"Brain-derived neurotrophic factor promotes human granulosa-like tumor cell steroidogenesis and proliferation by activating the FSH receptor-mediated signaling pathway","volume":"7","author":"Xie","year":"2017","journal-title":"Sci Rep-Uk"},{"issue":"1","key":"10.1016\/j.jep.2025.120935_bib40","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1080\/21655979.2020.1834726","article-title":"Systems pharmacology in combination with proteomics reveals underlying mechanisms of xihuang pill against triple-negative breast cancer","volume":"11","author":"Xu","year":"2020","journal-title":"Bioengineered"},{"issue":"1","key":"10.1016\/j.jep.2025.120935_bib41","doi-asserted-by":"crossref","DOI":"10.1186\/s13287-020-01769-6","article-title":"Recovery of ovarian function by human embryonic stem cell-derived mesenchymal stem cells in cisplatin-induced premature ovarian failure in mice","volume":"11","author":"Yoon","year":"2020","journal-title":"Stem Cell Res. Ther."},{"issue":"6","key":"10.1016\/j.jep.2025.120935_bib42","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1093\/humupd\/dmaa013","article-title":"Does an association exist between menstrual cycle length within the normal range and ovarian reserve biomarkers during the reproductive years? A systematic review and meta-analysis","volume":"26","author":"Younis","year":"2020","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jep.2025.120935_bib43","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/8470381","article-title":"Antineuroinflammatory effects of modified wu-zi-yan-zong prescription in \u03b2-Amyloid-Stimulated BV2 microglia via the NF-\u03b2 and ERK\/p38 MAPK signaling pathways","author":"Yu","year":"2017","journal-title":"Evid-Based Compl Alt"},{"issue":"21","key":"10.1016\/j.jep.2025.120935_bib44","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1080\/15384101.2016.1208873","article-title":"Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-B pathway","volume":"15","author":"Yuan","year":"2016","journal-title":"Cell Cycle"},{"issue":"1","key":"10.1016\/j.jep.2025.120935_bib45","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jep.2010.03.018","article-title":"Neuroprotective effect of modified wu-zi-yan-zong granule, a traditional Chinese herbal medicine, on CoCl-induced PC12 cells","volume":"130","author":"Zeng","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.120935_bib46","doi-asserted-by":"crossref","DOI":"10.1186\/s12958-018-0450-y","article-title":"MicroRNAs in ovarian follicular atresia and granulosa cell apoptosis","volume":"17","author":"Zhang","year":"2019","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"1","key":"10.1016\/j.jep.2025.120935_bib47","article-title":"Effects of qilin pills on spermatogenesis, reproductive hormones, oxidative stress, and the TSSK2 gene in a rat model of oligoasthenospermia","volume":"20","author":"Zhang","year":"2020","journal-title":"Bmc Complement Med"},{"key":"10.1016\/j.jep.2025.120935_bib48","article-title":"Moxibustion ameliorates ovarian function in premature ovarian insufficiency rats by activating cAMP\/PKA\/CREB to promote steroidogenesis in ovarian granulosa cells","volume":"242","author":"Zhao","year":"2024","journal-title":"J. Steroid Biochem."},{"issue":"32","key":"10.1016\/j.jep.2025.120935_bib49","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000043863","article-title":"Effects of interventional fallopian tube recanalization with ozone combined with Salvia miltiorrhiza injection and qilin pill on tubal obstructive infertility","volume":"104","author":"Zheng","year":"2025","journal-title":"Medicine"},{"issue":"41","key":"10.1016\/j.jep.2025.120935_bib50","doi-asserted-by":"crossref","first-page":"25488","DOI":"10.1039\/C7RA01478C","article-title":"Investigation into the pharmacokinetic-pharmacodynamic model of zingiberis rhizoma\/zingiberis rhizoma carbonisata and contribution to their therapeutic material basis using artificial neural networks","volume":"7","author":"Zhou","year":"2017","journal-title":"RSC Adv."},{"issue":"17","key":"10.1016\/j.jep.2025.120935_bib51","first-page":"1540","article-title":"Effects of qilin pills on fertility and HIF-1\u03b1\/Bnip3\/Beclin1 signaling pathway in ovarian tissues in diminished ovarian reserve model mice","volume":"62","author":"Zhu","year":"2021","journal-title":"J. Tradit. Chin. Med."},{"issue":"4","key":"10.1016\/j.jep.2025.120935_bib52","first-page":"1989","article-title":"Effects of qilin pills on ovarian reserve function in cyclophosphamide-induced decreased orarian reserve mice model based on autophagy","volume":"36","author":"Zhu","year":"2021","journal-title":"China J. Traditional Chinese Med. Pharm."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874125016277?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874125016277?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T03:03:24Z","timestamp":1776135804000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874125016277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":52,"alternative-id":["S0378874125016277"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2025.120935","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcriptomic, artificial neural network and Chou-Talalay analysis based investigation of potential mechanism and active components of Qi-Lin pill in treating diminished ovarian reserve","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2025.120935","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"120935"}}