{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T08:43:50Z","timestamp":1783413830305,"version":"3.54.6"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100008402","name":"Chengdu University of TCM","doi-asserted-by":"publisher","award":["LH202402027"],"award-info":[{"award-number":["LH202402027"]}],"id":[{"id":"10.13039\/501100008402","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008402","name":"Chengdu University of TCM","doi-asserted-by":"publisher","award":["QJRC2024034"],"award-info":[{"award-number":["QJRC2024034"]}],"id":[{"id":"10.13039\/501100008402","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82204765"],"award-info":[{"award-number":["82204765"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81803846"],"award-info":[{"award-number":["81803846"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.jep.2025.121034","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T08:04:45Z","timestamp":1765440285000},"page":"121034","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Inhibition of joint inflammation in rheumatoid arthritis by Wuwei Ganlu Medicinal Bath Granules via blocking toll-like receptor 4\/nuclear factor-kappa B and NOD-like Receptor Pyrin Domain-Containing 3 signaling"],"prefix":"10.1016","volume":"359","author":[{"given":"Tianhong","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nengqiao","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bojun","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuemei","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cairang","family":"Guanque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinsong","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2025.121034_bib1","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1084\/jem.20172222","article-title":"Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity","volume":"215","author":"Boucher","year":"2018","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jep.2025.121034_bib3","doi-asserted-by":"crossref","first-page":"9580","DOI":"10.1080\/10408398.2022.2067121","article-title":"Kaempferol: a flavonoid with wider biological activities and its applications","volume":"63","author":"Bangar","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.jep.2025.121034_bib4","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1038\/nprot.2007.173","article-title":"Collagen-induced arthritis","volume":"2","author":"Brand","year":"2007","journal-title":"Nat. Protoc."},{"issue":"17","key":"10.1016\/j.jep.2025.121034_bib5","first-page":"55","article-title":"Research progress on external therapy of Tibetan medicine in the treatment of rheumatoid arthritis","volume":"28","author":"Chen","year":"2019","journal-title":"Chin. J. Ethnomed. Ethnopharmacy"},{"key":"10.1016\/j.jep.2025.121034_bib6","first-page":"6657","article-title":"A new analysis of \" Wuwei Ganlu Medicine bath\" in Tibetan medicine. China J","volume":"37","author":"Cairang","year":"2022","journal-title":"Chin. Mater. Med"},{"key":"10.1016\/j.jep.2025.121034_bib7","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.3389\/fimmu.2019.01620","article-title":"A novel phytochemical, DIM, inhibits proliferation, migration, invasion and TNF-\u03b1 induced inflammatory cytokine production of synovial fibroblasts from rheumatoid arthritis patients by targeting MAPK and AKT\/mTOR signal pathway","volume":"10","author":"Du","year":"2019","journal-title":"Front. Immunol."},{"issue":"23","key":"10.1016\/j.jep.2025.121034_bib8","first-page":"100","article-title":"Efficacy of the Wuwei Ganlu bath therapy of Tibetan medicine on atrophic arthritis","volume":"10","author":"Duo","year":"2018","journal-title":"Clin. Res. Tradit. Chin. Med"},{"key":"10.1016\/j.jep.2025.121034_bib9","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/8042097","article-title":"Chlorogenic acid inhibits BAFF expression in collagen-induced arthritis and human synoviocyte MH7A cells by modulating the activation of the NF-\u03baB signaling pathway","volume":"2019","author":"Fu","year":"2019","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.jep.2025.121034_bib10","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/j.immuni.2016.01.012","article-title":"Human monocytes engage an alternative inflammasome pathway","volume":"44","author":"Gaidt","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.jep.2025.121034_bib12","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/cei.13167","article-title":"NLRP3 inflammasome activation contributes to the pathogenesis of rheumatoid arthritis","volume":"194","author":"Guo","year":"2018","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.jep.2025.121034_bib13","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1172\/JCI12466","article-title":"c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis","volume":"108","author":"Han","year":"2001","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.jep.2025.121034_bib14","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1038\/s41423-021-00740-6","article-title":"NLRP3 inflammasome activation and cell death","volume":"18","author":"Huang","year":"2021","journal-title":"Cell. Mol. Immunol."},{"issue":"5","key":"10.1016\/j.jep.2025.121034_bib15","first-page":"45","article-title":"Comparison of various special staining methods applied in the histomorphology study of osteoarthritis","volume":"21","author":"Huang","year":"2011","journal-title":"Chin. J. Comp. Med."},{"key":"10.1016\/j.jep.2025.121034_bib16","first-page":"63","article-title":"Research progress of minority medicine in the treatment of rheumatoid arthritis","volume":"37","author":"Jiang","year":"2023","journal-title":"J. Practical Traditional Chin. Internal Med."},{"key":"10.1016\/j.jep.2025.121034_bib17","doi-asserted-by":"crossref","DOI":"10.3390\/ijms222010922","article-title":"Cytokine networks in the pathogenesis of rheumatoid arthritis","volume":"22","author":"Kondo","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2025.121034_bib18","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1002\/jssc.201701249","article-title":"HPLC-MS\/MS determination of flavonoids in Gleditsiae Spina for its quality assessment","volume":"41","author":"Li","year":"2018","journal-title":"J. Separ. Sci."},{"key":"10.1016\/j.jep.2025.121034_bib19","doi-asserted-by":"crossref","first-page":"9869","DOI":"10.1021\/acs.jmedchem.3c02407","article-title":"Discovery and development of NLRP3 inhibitors targeting the LRR domain to disrupt NLRP3-NEK7 interaction for the treatment of rheumatoid arthritis","volume":"67","author":"Li","year":"2024","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jep.2025.121034_bib20","article-title":"Update on the pathomechanism, diagnosis, and treatment options for rheumatoid arthritis","volume":"9","author":"Lin","year":"2020","journal-title":"Cells"},{"issue":"6","key":"10.1016\/j.jep.2025.121034_bib21","first-page":"855","article-title":"Clinical study on the treatment of rheumatoid arthritis by Wuwei Ganlu Medicinal Bath Granules","volume":"10","author":"Liu","year":"2012","journal-title":"Chin. J. General Practice"},{"issue":"3","key":"10.1016\/j.jep.2025.121034_bib22","first-page":"171","article-title":"Clinical research of Tibetan medicated bathing integrative therapy for rheumatoid arthritis","volume":"13","author":"Liu","year":"2023","journal-title":"Chin. Med. Pharm."},{"key":"10.1016\/j.jep.2025.121034_bib23","doi-asserted-by":"crossref","first-page":"499","DOI":"10.3109\/08923973.2015.1095763","article-title":"Chlorogenic acid and luteolin synergistically inhibit the proliferation of interleukin-1\u03b2-induced fibroblast-like synoviocytes through regulating the activation of NF-\u03baB and JAK\/STAT-signaling pathways","volume":"37","author":"Lou","year":"2015","journal-title":"Immunopharmacol. Immunotoxicol."},{"issue":"8","key":"10.1016\/j.jep.2025.121034_bib24","article-title":"Progression on Chinese materia medica inhibits rheumatoid arthritis through NF-\u03baB signaling pathway","volume":"22","author":"Ma","year":"2025","journal-title":"CMH"},{"key":"10.1016\/j.jep.2025.121034_bib25","doi-asserted-by":"crossref","first-page":"596","DOI":"10.2174\/1389201021666191210114127","article-title":"Evaluation of anti-inflammatory effects of Choerospondias axillaris Fruit's methanolic extract in synoviocytes and CIA Rat model","volume":"21","author":"Mann","year":"2020","journal-title":"Curr. Pharm. Biotechnol."},{"key":"10.1016\/j.jep.2025.121034_bib26","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.freeradbiomed.2019.01.026","article-title":"The influence of alkaloids on oxidative stress and related signaling pathways","volume":"134","author":"Mac\u00e1kov\u00e1","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.jep.2025.121034_bib27","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1177\/1947603511402665","article-title":"A comprehensive histological assessment of osteoarthritis lesions in mice","volume":"2","author":"McNulty","year":"2011","journal-title":"Cartilage"},{"key":"10.1016\/j.jep.2025.121034_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114657","article-title":"Daphnes cortex and its licorice-processed products suppress inflammation via the TLR4\/NF-\u03baB\/NLRP3 signaling pathway and regulation of the metabolic profile in the treatment of rheumatoid arthritis","volume":"283","author":"Meng","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.121034_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.155010","article-title":"Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-\u03baB and MAPK signaling pathways","volume":"119","author":"Meng","year":"2023","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2025.121034_bib30","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s00210-022-02212-8","article-title":"Ferulic acid prevents cyclosporine-induced nephrotoxicity in rats through exerting anti-oxidant and anti-inflammatory effects via activation of Nrf2\/HO-1 signaling and suppression of NF-\u03baB\/TNF-\u03b1 axis","volume":"395","author":"Nouri","year":"2022","journal-title":"Naunyn-Schmiedebergs Arch Pharmacol"},{"key":"10.1016\/j.jep.2025.121034_bib60","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1080\/02648725.2013.801236","article-title":"Post-transcriptional regulation of cytokine mRNA controls the initiation and resolution of inflammation","volume":"29","author":"Mino","year":"2013","journal-title":"Biotechnol Genet Eng Rev"},{"key":"10.1016\/j.jep.2025.121034_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.tice.2022.101826","article-title":"Tectoridin ameliorates proliferation and inflammation in TNF-\u03b1-induced HFLS-RA cells via suppressing the TLR4\/NLRP3\/NF-\u03baB signaling pathway","volume":"77","author":"Niu","year":"2022","journal-title":"Tissue Cell"},{"key":"10.1016\/j.jep.2025.121034_bib32","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/s41413-025-00419-y","article-title":"Tm4sf19 inhibition ameliorates inflammation and bone destruction in collagen-induced arthritis by suppressing TLR4-mediated inflammatory signaling and abnormal osteoclast activation","volume":"13","author":"Park","year":"2025","journal-title":"Bone Res."},{"issue":"15.5.1\u201315.5.24","key":"10.1016\/j.jep.2025.121034_bib33","article-title":"Collagen-induced arthritis","volume":"15","author":"Rosloniec","year":"2001","journal-title":"Curr Protoc Immunol Chapter"},{"issue":"1","key":"10.1016\/j.jep.2025.121034_bib35","first-page":"13","article-title":"Analysis of the chemical composition of Rhododendri Anthopgonoidi flos based on UPLC-Q-TOF-MS technique","volume":"48","author":"Sheng","year":"2025","journal-title":"J. Chengdu Univ. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2025.121034_bib36","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1016\/S0140-6736(16)30173-8","article-title":"Rheumatoid arthritis","volume":"388","author":"Smolen","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.jep.2025.121034_bib37","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1093\/rheumatology\/kem298","article-title":"Signalling, inflammation and arthritis: NF-kappaB and its relevance to arthritis and inflammation","volume":"47","author":"Simmonds","year":"2008","journal-title":"Rheumatology"},{"key":"10.1016\/j.jep.2025.121034_bib38","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/s00393-012-1083-8","article-title":"Evaluation of complete Freund's adjuvant-induced arthritis in a Wistar rat model. Comparison of thermography and histopathology","volume":"72","author":"Snekhalatha","year":"2013","journal-title":"Z. Rheumatol."},{"key":"10.1016\/j.jep.2025.121034_bib39","doi-asserted-by":"crossref","DOI":"10.1038\/nrdp.2018.1","article-title":"Rheumatoid arthritis","volume":"4","author":"Smolen","year":"2018","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.jep.2025.121034_bib40","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1038\/nri2725","article-title":"NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production?","volume":"10","author":"Tschopp","year":"2010","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jep.2025.121034_bib41","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1136\/ard.62.8.722","article-title":"Extra-articular disease manifestations in rheumatoid arthritis: incidence trends and risk factors over 46 years","volume":"62","author":"Turesson","year":"2003","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jep.2025.121034_bib42","doi-asserted-by":"crossref","first-page":"285","DOI":"10.2147\/ITT.S288547","article-title":"Contribution of toll-like receptors and the NLRP3 inflammasome in rheumatoid arthritis pathophysiology","volume":"10","author":"Unterberger","year":"2021","journal-title":"ImmunoTargets Ther."},{"key":"10.1016\/j.jep.2025.121034_bib43","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1002\/1529-0131(200107)44:7<1515::AID-ART273>3.0.CO;2-7","article-title":"Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study","volume":"44","author":"van Ede","year":"2001","journal-title":"Arthritis Rheum."},{"issue":"2","key":"10.1016\/j.jep.2025.121034_bib44","first-page":"35","article-title":"Molecular mechanism of Tibetan medicine \"Wuwei Ganlu\" medicinal bath granules on adjuvant-induced arthritis in rats","volume":"12","author":"Wang","year":"2021","journal-title":"Pharm. Clin. Chin. Mater. Med."},{"key":"10.1016\/j.jep.2025.121034_bib45","article-title":"Systems Study on the antirheumatic mechanism of Tibetan medicinal-bath therapy using wuwei-ganlu-yaoyu-keli","author":"Wang","year":"2017","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.jep.2025.121034_bib46","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1080\/10826070903574352","article-title":"Preparative isolation and purification of flavone C-Glycosides from the leaves of Ficus microcarpa L. f by medium-pressure liquid chromatography, high-speed countercurrent chromatography, and preparative liquid chromatography","volume":"33","author":"Wang","year":"2010","journal-title":"J. Liq. Chromatogr. Relat. Technol."},{"key":"10.1016\/j.jep.2025.121034_bib47","doi-asserted-by":"crossref","first-page":"3497","DOI":"10.2147\/DDDT.S227738","article-title":"The osteoprotective effects of kaempferol: the evidence from in vivo and in vitro studies","volume":"13","author":"Wong","year":"2019","journal-title":"Drug Des. Dev. Ther."},{"issue":"11","key":"10.1016\/j.jep.2025.121034_bib48","first-page":"3656","article-title":"UPLC-Q-TOF\/MS-based analysis on the chemical constituents of different Myricariae Ramulus species","volume":"45","author":"Wu","year":"2023","journal-title":"Chin. Tradit. Pat. Med."},{"key":"10.1016\/j.jep.2025.121034_bib50","article-title":"Lignans in resin of Araucaria angustifolia by gas chromatography\/mass spectrometry","volume":"JMS 39","author":"Yamamoto","year":"2004","journal-title":"J. Mass Spectrom."},{"key":"10.1016\/j.jep.2025.121034_bib51","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.931690","article-title":"Role of NLRP3 inflammasome in rheumatoid arthritis","volume":"13","author":"Yin","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jep.2025.121034_bib52","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1007\/s00296-011-1825-y","article-title":"ASC plays a role in the priming phase of the immune response to type II collagen in collagen-induced arthritis","volume":"32","author":"Yamazaki","year":"2012","journal-title":"Rheumatol. Int."},{"key":"10.1016\/j.jep.2025.121034_bib53","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1002\/art.41666","article-title":"Characterization and function of tumor necrosis factor and Interleukin-6-Induced osteoclasts in rheumatoid arthritis","volume":"73","author":"Yokota","year":"2021","journal-title":"Arthritis Rheumatol."},{"issue":"19","key":"10.1016\/j.jep.2025.121034_bib54","first-page":"1801","article-title":"Different special staining methods on cartilage tissue of osteoarthritis morphology: a comparison study","volume":"23","author":"Yu","year":"2015","journal-title":"Orthop. J. China,"},{"issue":"Pt A","key":"10.1016\/j.jep.2025.121034_bib55","article-title":"Panaxynol induces fibroblast-like synovial cell apoptosis, inhibits proliferation and invasion through TLR4\/NF-\u03baB pathway to alleviate rheumatoid arthritis","volume":"101","author":"Zhao","year":"2021","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jep.2025.121034_bib56","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.talanta.2012.11.012","article-title":"Diagnostic fragment-ion-based and extension strategy coupled to DFIs intensity analysis for identification of chlorogenic acids isomers in Flos Lonicerae Japonicae by HPLC-ESI-MS(n)","volume":"104","author":"Zhang","year":"2013","journal-title":"Talanta"},{"key":"10.1016\/j.jep.2025.121034_bib57","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/9656270","article-title":"NLRP3 inflammasome plays an important role in the pathogenesis of collagen-induced arthritis","volume":"2016","author":"Zhang","year":"2016","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.jep.2025.121034_bib58","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.1083788","article-title":"Berberine a traditional Chinese drug repurposing: its actions in inflammation-associated ulcerative colitis and cancer therapy","volume":"13","author":"Zhu","year":"2022","journal-title":"Front. Immunol."},{"issue":"9","key":"10.1016\/j.jep.2025.121034_bib59","first-page":"74","article-title":"Research progress on a kind of Tibetan medicated bath Wuweiganlu","volume":"31","author":"Zhuoma","year":"2025","journal-title":"Chin. J. Ethn. Med"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874125017271?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874125017271?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T17:49:13Z","timestamp":1777571353000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874125017271"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":56,"alternative-id":["S0378874125017271"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2025.121034","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhibition of joint inflammation in rheumatoid arthritis by Wuwei Ganlu Medicinal Bath Granules via blocking toll-like receptor 4\/nuclear factor-kappa B and NOD-like Receptor Pyrin Domain-Containing 3 signaling","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2025.121034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"121034"}}