{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T23:32:32Z","timestamp":1793403152596,"version":"4.5.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.jep.2025.121081","type":"journal-article","created":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T07:17:53Z","timestamp":1766647073000},"page":"121081","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Dandelion alleviates Helicobacter pylori associated gastritis by inhibiting proteolytic activity of HtrA"],"prefix":"10.1016","volume":"359","author":[{"given":"Li","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianqiong","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwen","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuilong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kui","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiumin","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3696-7590","authenticated-orcid":false,"given":"Yan","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jep.2025.121081_bib1","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-15361-w","article-title":"Irigenin, a novel lead from Iris confusa for management of Helicobacter pylori infection with selective COX-2 and HpIMPDH inhibitory potential","volume":"12","author":"Abdel-Baki","year":"2022","journal-title":"Sci. Rep."},{"issue":"13","key":"10.1016\/j.jep.2025.121081_bib2","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.3760\/cma.j.issn.0366-6999.20140615","article-title":"Anti- helicobacter pylori effect of total alkaloids of sophora alopecuroides in vivo","volume":"127","author":"Aiping","year":"2024","journal-title":"Chin. Med. J."},{"issue":"12","key":"10.1016\/j.jep.2025.121081_bib3","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1007\/s00203-022-03314-w","article-title":"The impacts of probiotics in eradication therapy of Helicobacter pylori","volume":"204","author":"Bai","year":"2022","journal-title":"Arch. Microbiol."},{"issue":"1","key":"10.1016\/j.jep.2025.121081_bib4","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3390\/cells10010027","article-title":"Helicobacter pylori virulence factors\u2014mechanisms of bacterial pathogenicity in the gastric microenvironment","volume":"10","author":"Baj","year":"2020","journal-title":"Cells"},{"issue":"24","key":"10.1016\/j.jep.2025.121081_bib5","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.21037\/atm-22-5421","article-title":"The comparative efficacy and safety of 9 traditional Chinese medicines combined with standard quadruple therapy for Helicobacter pylori-associated gastritis: a systematic review and network meta-analysis","volume":"10","author":"Bao","year":"2022","journal-title":"Ann. Transl. Med."},{"key":"10.1016\/j.jep.2025.121081_bib6","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-67578-2","article-title":"A novel FRET peptide assay reveals efficient Helicobacter pylori HtrA inhibition through zinc and copper binding","volume":"10","author":"Bernegger","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2025.121081_bib7","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s12964-021-00788-x","article-title":"Identification of Desmoglein-2 as a novel target of Helicobacter pylori HtrA in epithelial cells","volume":"19","author":"Bernegger","year":"2021","journal-title":"Cell Commun. Signal."},{"issue":"1","key":"10.1016\/j.jep.2025.121081_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0280810","article-title":"A comprehensive analysis of chemical and biological pollutants (natural and anthropogenic origin) of soil and dandelion (Taraxacum officinale) samples","volume":"18","author":"Bogu\u015b","year":"2023","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.jep.2025.121081_bib9","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.3390\/ph16091308","article-title":"Treatment of chronic gastritis with traditional Chinese medicine: pharmacological activities and mechanisms","volume":"16","author":"Chen","year":"2023","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.jep.2025.121081_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.125274","article-title":"Crystal structures and solution conformations of HtrA from Helicobacter pylori reveal pH-dependent oligomeric conversion and conformational rearrangements","volume":"243","author":"Cui","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"issue":"6","key":"10.1016\/j.jep.2025.121081_bib11","doi-asserted-by":"crossref","DOI":"10.1002\/cbdv.202400140","article-title":"Potentialities of dandelion (Taraxacum Mongolicum Hand.-Mazz.) flower extracts on gastric protection against Helicobacter pylori and characterization of its bioactive constituents","volume":"21","author":"Dong","year":"2024","journal-title":"Chem. Biodivers."},{"issue":"2","key":"10.1016\/j.jep.2025.121081_bib12","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1142\/S0192415X20500238","article-title":"Taraxacum officinale wigg. Attenuates inflammatory responses in murine microglia through the Nrf2\/HO-1 and NF-\u03baB signaling pathways","volume":"48","author":"Dong","year":"2020","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.jep.2025.121081_bib13","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1016\/j.intimp.2025.114620","article-title":"Nicotinamide mononucleotide ameliorates hypertriglyceridemia pancreatitis via NAD+\/SIRT1-mediated TXNIP suppression and NOTCH pathway for accelerated repair-associated processes","volume":"155","author":"Duan","year":"2025","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jep.2025.121081_bib14","doi-asserted-by":"crossref","DOI":"10.1007\/s11030-025-11137-2","article-title":"Molecular dynamics simulation-driven focused virtual screening and experimental validation of fisetin as an inhibitor of Helicobacter pylori HtrA protease","author":"Gao","year":"2025","journal-title":"Mol. Divers."},{"key":"10.1016\/j.jep.2025.121081_bib15","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.3389\/fimmu.2019.02326","article-title":"Lactobacillus gasseri suppresses the production of proinflammatory cytokines in helicobacter pylori-infected macrophages by inhibiting the expression of ADAM17","volume":"10","author":"Gebremariam","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jep.2025.121081_bib16","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.micpath.2017.06.023","article-title":"Relationship between histopathological status of the Helicobacter pylori infected patients and proteases of H. pylori in isolates carrying diverse virulence genotypes","volume":"110","author":"Gharibi","year":"2017","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.jep.2025.121081_bib17","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s13099-017-0189-6","article-title":"Overexpression of serine protease HtrA enhances disruption of adherens junctions, paracellular transmigration and type IV secretion of CagA by Helicobacter pylori","volume":"9","author":"Harrer","year":"2017","journal-title":"Gut Pathog."},{"key":"10.1016\/j.jep.2025.121081_bib18","doi-asserted-by":"crossref","first-page":"159","DOI":"10.3389\/fcimb.2016.00159","article-title":"Adhesion and invasion of gastric mucosa epithelial cells by Helicobacter pylori","volume":"6","author":"Huang","year":"2016","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"8_Suppl. ment_1","key":"10.1016\/j.jep.2025.121081_bib19","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1158\/1538-7445.AM2025-1618","article-title":"Abstract 1618: blocking MDM2 induces downregulation of PARP and enhances apoptosis in SK-N-SH neuroblastoma cells","volume":"85","author":"Jaganathan","year":"2025","journal-title":"Cancer Res."},{"issue":"4","key":"10.1016\/j.jep.2025.121081_bib20","first-page":"357","article-title":"[Comparative study on Jinghua Weikang capsule and famotidine in treating duodenal ulcer]","volume":"26","author":"Ji","year":"2006","journal-title":"Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chin. J. Integrated Tradit. West Med."},{"issue":"2","key":"10.1016\/j.jep.2025.121081_bib21","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/1751-7915.13807","article-title":"Armeniaspirol A: a novel anti-helicobacter pylori agent","volume":"15","author":"Jia","year":"2021","journal-title":"Microb. Biotechnol."},{"issue":"7","key":"10.1016\/j.jep.2025.121081_bib22","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1111\/jcmm.17219","article-title":"DEC1 promotes progression of helicobacter pylori-positive gastric cancer by regulating Akt\/NF-\u03baB pathway","volume":"26","author":"Jia","year":"2022","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.jep.2025.121081_bib23","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jare.2018.01.007","article-title":"Recent advances in design of new urease inhibitors: a review","volume":"13","author":"Kafarski","year":"2018","journal-title":"J. Adv. Res."},{"issue":"11","key":"10.1016\/j.jep.2025.121081_bib24","doi-asserted-by":"crossref","first-page":"3194","DOI":"10.3390\/cells10113194","article-title":"Macrophage reprogramming and cancer therapeutics: role of iNOS-Derived NO","volume":"10","author":"Kashfi","year":"2021","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.jep.2025.121081_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jep.2012.12.009","article-title":"The aerial part of Taraxacum coreanum extract has an anti-inflammatory effect on peritoneal macrophages in vitro and increases survival in a mouse model of septic shock","volume":"146","author":"Lee","year":"2012","journal-title":"J. Ethnopharmacol."},{"issue":"22","key":"10.1016\/j.jep.2025.121081_bib26","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232213997","article-title":"Bamboo salt and triple therapy synergistically inhibit helicobacter pylori-Induced gastritis in vivo: a preliminary study","volume":"23","author":"Lee","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2025.121081_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115272","article-title":"The potential of dandelion in the fight against gastrointestinal diseases: a review","volume":"293","author":"Li","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.121081_bib28","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.foodres.2018.03.012","article-title":"Assessment of effects of phenolic fractions from leaves and petals of dandelion in selected components of hemostasis","volume":"107","author":"Lis","year":"2018","journal-title":"Food Res. Int."},{"issue":"3","key":"10.1016\/j.jep.2025.121081_bib29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0017986","article-title":"Inhibitors of Helicobacter pylori protease HtrA found by 'virtual ligand' screening combat bacterial invasion of epithelia","volume":"6","author":"L\u00f6wer","year":"2011","journal-title":"PLoS One"},{"issue":"44","key":"10.1016\/j.jep.2025.121081_bib30","doi-asserted-by":"crossref","first-page":"5629","DOI":"10.3748\/wjg.v16.i44.5629","article-title":"Screening test for anti-helicobacter pylori activity of traditional Chinese herbal medicines","volume":"16","author":"Ma","year":"2010","journal-title":"World J. Gastroenterol."},{"issue":"4","key":"10.1016\/j.jep.2025.121081_bib31","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1136\/gutjnl-2023-329712","article-title":"Empiric use of standard triple therapy in Helicobacter pylori eradication does not require readjustment in the clarithromycin resistance cut-off point","volume":"73","author":"Malfertheiner","year":"2024","journal-title":"Gut"},{"issue":"6","key":"10.1016\/j.jep.2025.121081_bib32","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1159\/000007569","article-title":"Comparison of omeprazole, metronidazole and clarithromycin with omeprazole\/amoxicillin dual-therapy for the cure of Helicobacter pylori infection","volume":"59","author":"Miehlke","year":"1998","journal-title":"Digestion"},{"key":"10.1016\/j.jep.2025.121081_bib33","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s12010-021-03716-4","article-title":"Study on the interaction of algal peptides on virulence factors of helicobacter pylori: in silico approach","volume":"194","author":"MubarakAli","year":"2021","journal-title":"Appl. Biochem. Biotechnol."},{"issue":"1","key":"10.1016\/j.jep.2025.121081_bib34","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/2008-2231-20-72","article-title":"Large scale screening of commonly used Iranian traditional medicinal plants against urease activity","volume":"20","author":"Nabati","year":"2012","journal-title":"DARU J. Pharm. Sci."},{"key":"10.1016\/j.jep.2025.121081_bib35","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.jep.2018.01.025","article-title":"Gastroprotective effects of Hwanglyeonhaedok-tang against helicobacter pylori-induced gastric cell injury","volume":"216","author":"Park","year":"2018","journal-title":"J. Ethnopharmacol."},{"issue":"35","key":"10.1016\/j.jep.2025.121081_bib36","doi-asserted-by":"crossref","first-page":"10244","DOI":"10.1002\/anie.201504035","article-title":"Fragment\u2010Based De Novo Design Reveals a Small\u2010Molecule Inhibitor of Helicobacter Pylori HtrA","volume":"54","author":"Perna","year":"2015","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.jep.2025.121081_bib37","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1758-2946-6-S1-P46","article-title":"Peptide lineup against Gram-negative bacterial infection \u2013 first-in-class peptide inhibitor of H. pylori HtrA","volume":"6","author":"Perna","year":"2014","journal-title":"J. Cheminf."},{"issue":"1","key":"10.1016\/j.jep.2025.121081_bib38","doi-asserted-by":"crossref","first-page":"3394","DOI":"10.1002\/fsn3.3329","article-title":"Anti-helicobacter pylori activity of Fagopyrum tataricum (L.) gaertn. Bran flavonoids extract and its effect on helicobacter pylori-induced inflammatory response","volume":"11","author":"Qing","year":"2023","journal-title":"Food Sci. Nutr."},{"issue":"1","key":"10.1016\/j.jep.2025.121081_bib39","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/s41420-022-01059-5","article-title":"Taraxasterol prompted the anti-tumor effect in mice burden hepatocellular carcinoma by regulating T lymphocytes","volume":"8","author":"Ren","year":"2022","journal-title":"Cell Death Discov."},{"issue":"3","key":"10.1016\/j.jep.2025.121081_bib40","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.3390\/ijms24032895","article-title":"Helicobacter pylori and gastric cancer: pathogenetic mechanisms","volume":"24","author":"Salvatori","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"8","key":"10.1016\/j.jep.2025.121081_bib41","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/j.chom.2023.06.016","article-title":"A single-nucleotide polymorphism in Helicobacter pylori promotes gastric cancer development","volume":"31","author":"Sharafutdinov","year":"2023","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jep.2025.121081_bib42","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2024.1395403","article-title":"The immunopathogenesis of helicobacter pylori-induced gastric cancer: a narrative review","volume":"15","author":"Shirani","year":"2024","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jep.2025.121081_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.157191","article-title":"Evidences for the mechanism of anti-inflammatory effect of coptisine acting against clarithromycin-resistant Helicobacter pylori","volume":"147","author":"Tang","year":"2025","journal-title":"Phytomedicine"},{"issue":"5","key":"10.1016\/j.jep.2025.121081_bib44","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1111\/mmi.13276","article-title":"Characterisation of worldwide Helicobacter pylori strains reveals genetic conservation and essentiality of serine protease HtrA","volume":"99","author":"Tegtmeyer","year":"2015","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.jep.2025.121081_bib45","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s12866-022-02463-8","article-title":"Emergence of amoxicillin resistance and identification of novel mutations of the pbp1A gene in Helicobacter pylori in Vietnam","volume":"22","author":"Tran","year":"2022","journal-title":"BMC Microbiol."},{"issue":"10","key":"10.1016\/j.jep.2025.121081_bib46","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.it.2005.07.008","article-title":"A function for the macrophage F4\/80 molecule in tolerance induction","volume":"26","author":"Vandenberg","year":"2005","journal-title":"Trends Immunol."},{"key":"10.1016\/j.jep.2025.121081_bib47","article-title":"Therapeutic potential of isochlorogenic acid A from Taraxacum officinale in improving immune response and enhancing the efficacy of PD-1\/PD-L1 blockade in triple-negative breast cancer","volume":"16","author":"Wang","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jep.2025.121081_bib48","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1186\/s12964-024-01627-5","article-title":"Helicobacter pylori disrupts gastric mucosal homeostasis by stimulating macrophages to secrete CCL3","volume":"22","author":"Wei","year":"2024","journal-title":"Cell Commun. Signal."},{"key":"10.1016\/j.jep.2025.121081_bib49","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s12964-017-0162-5","article-title":"Bacterial serine protease HtrA as a promising new target for antimicrobial therapy?","volume":"15","author":"Wessler","year":"2017","journal-title":"Cell Commun. Signal."},{"issue":"Pt B","key":"10.1016\/j.jep.2025.121081_bib50","article-title":"Epiberberine inhibits Helicobacter pylori and reduces host apoptosis and inflammatory damage by down-regulating urease expression","volume":"318","author":"Wu","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"11","key":"10.1016\/j.jep.2025.121081_bib51","doi-asserted-by":"crossref","first-page":"5032","DOI":"10.1039\/D3FO00099K","article-title":"Phenyl lactic acid alleviates Helicobacter pylori infection in C57BL\/6 mice","volume":"14","author":"Wu","year":"2023","journal-title":"Food Funct."},{"key":"10.1016\/j.jep.2025.121081_bib52","first-page":"10","article-title":"Dandelion extract suppresses reactive oxidative species and inflammasome in intestinal epithelial cells","author":"Xue","year":"2016","journal-title":"J. Funct.Foods"},{"key":"10.1016\/j.jep.2025.121081_bib53","article-title":"In-vitro anti-helicobacter pylori activity and preliminary mechanism of action of Canarium album raeusch. fruit extracts","volume":"283","author":"Yan","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2025.121081_bib54","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.jep.2017.06.045","article-title":"Gastroprotective actions of Taraxacum coreanum nakai water extracts in ethanol-induced rat models of acute and chronic gastritis","volume":"208","author":"Yang","year":"2017","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.jep.2025.121081_bib55","first-page":"34","article-title":"Dandelion (Taraxacum officinale and T mongolicum)","volume":"8","author":"Yarnell","year":"2009","journal-title":"Integr. Med.: Clin. J."},{"key":"10.1016\/j.jep.2025.121081_bib56","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1038\/s41467-025-56720-1","article-title":"Endothelial SHANK3 regulates tight junctions in the neonatal mouse blood-brain barrier through \u03b2-Catenin signaling","volume":"16","author":"Yong-Eun","year":"2025","journal-title":"Nat. Commun."},{"issue":"38","key":"10.1016\/j.jep.2025.121081_bib57","doi-asserted-by":"crossref","first-page":"11981","DOI":"10.1021\/acs.jafc.2c03711","article-title":"Urolithin A attenuates helicobacter pylori-induced damage in vivo","volume":"70","author":"Yu","year":"2022","journal-title":"J. Agric. Food Chem."},{"issue":"1","key":"10.1016\/j.jep.2025.121081_bib58","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1186\/s12964-019-0481-9","article-title":"Chaperone activity of serine protease HtrA of Helicobacter pylori as a crucial survival factor under stress conditions","volume":"17","author":"Zarzecka","year":"2019","journal-title":"Cell Commun. Signal."},{"issue":"1","key":"10.1016\/j.jep.2025.121081_bib60","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/s41467-024-44860-9","article-title":"LOX-1 acts as an N6-methyladenosine-regulated receptor for Helicobacter pylori by binding to the bacterial catalase","volume":"15","author":"Zeng","year":"2024","journal-title":"Nat. Commun."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037887412501774X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037887412501774X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T17:48:31Z","timestamp":1777571311000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S037887412501774X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":59,"alternative-id":["S037887412501774X"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2025.121081","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dandelion alleviates Helicobacter pylori associated gastritis by inhibiting proteolytic activity of HtrA","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2025.121081","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"121081"}}