{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:37:40Z","timestamp":1793039860629,"version":"4.5.0"},"reference-count":195,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010950","name":"Department of Science and Technology of Henan Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013066","name":"Key Scientific Research Project of Colleges and Universities in Henan Province","doi-asserted-by":"publisher","award":["23A360008"],"award-info":[{"award-number":["23A360008"]}],"id":[{"id":"10.13039\/501100013066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004773","name":"Henan University","doi-asserted-by":"publisher","award":["2023KYCX063"],"award-info":[{"award-number":["2023KYCX063"]}],"id":[{"id":"10.13039\/501100004773","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017634","name":"Henan University of Chinese Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017634","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.jep.2026.121261","type":"journal-article","created":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T16:50:12Z","timestamp":1769187012000},"page":"121261","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Potential of traditional Chinese medicine-antibiotic combinations in combating multidrug-resistant organisms: Advances, mechanisms, and clinical implications"],"prefix":"10.1016","volume":"361","author":[{"given":"Xi","family":"Qin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yali","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weixia","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingliang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linhong","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liuqing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinfa","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib1","first-page":"345","article-title":"Frequency of multi-drug resistance and molecular characteristics of resistance to colistin in Acinetobacter baumannii collected from patients in intensive care units with ventilator-associated pneumonia","volume":"20","author":"Babaei","year":"2021","journal-title":"Tanaffos"},{"issue":"6","key":"10.1016\/j.jep.2026.121261_bib2","doi-asserted-by":"crossref","first-page":"5777","DOI":"10.3390\/ijms24065777","article-title":"Antibiotics and bacterial Resistance-a short story of an endless arms race","volume":"24","author":"Baran","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.jep.2026.121261_bib3","doi-asserted-by":"crossref","first-page":"931","DOI":"10.3390\/jcm14030931","article-title":"Unveiling the resistome landscape in peri-implant health and disease","volume":"14","author":"Bessa","year":"2025","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.jep.2026.121261_bib4","article-title":"Tanreqing combined with azithromycin sequential treatment of mycoplasma pneumonia in children: a clinical observation of 60 cases","author":"Bi","year":"2007","journal-title":"Changchun Uni. Chin. Med."},{"issue":"7","key":"10.1016\/j.jep.2026.121261_bib5","doi-asserted-by":"crossref","first-page":"2965","DOI":"10.1128\/AAC.49.7.2965-2971.2005","article-title":"Structural and functional study of the phenicol-specific efflux pump FloR belonging to the major facilitator superfamily","volume":"49","author":"Braibant","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib6","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-36005-y","article-title":"Mechanisms of fitness cost reduction for rifampicin-resistant strains with deletion or duplication mutations in rpoB","volume":"8","author":"Brandis","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2026.121261_bib8","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.ijfoodmicro.2004.03.022","article-title":"Essential oils: their antibacterial properties and potential applications in foods-a review","volume":"94","author":"Burt","year":"2004","journal-title":"Int. J. Food Microbiol."},{"issue":"16","key":"10.1016\/j.jep.2026.121261_bib9","doi-asserted-by":"crossref","first-page":"3619","DOI":"10.3390\/molecules25163619","article-title":"Naturally-occurring alkaloids of plant origin as potential antimicrobials against antibiotic-resistant infections","volume":"25","author":"Casciaro","year":"2020","journal-title":"Molecules"},{"issue":"6","key":"10.1016\/j.jep.2026.121261_bib10","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1021\/acs.jnatprod.1c01107","article-title":"Chemically tuning resveratrol for the effective killing of gram-positive pathogens","volume":"85","author":"Cebri\u00e1n","year":"2022","journal-title":"J. Nat. Prod."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib12","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.jep.2011.06.039","article-title":"Synergistic effects of baicalein with ciprofloxacin against NorA over-expressed methicillin-resistant Staphylococcus aureus (MRSA) and inhibition of MRSA pyruvate kinase","volume":"137","author":"Chan","year":"2011","journal-title":"J. Ethnopharmacol."},{"issue":"5","key":"10.1016\/j.jep.2026.121261_bib13","first-page":"752","article-title":"Effects of Coptis chinensis franch., Paeonia lactiflora pall. and Rheum officinale baill. on the release of endotoxin from Escherichia coli","author":"Chang","year":"2007","journal-title":"Chin. Tradit. Pat. Med."},{"issue":"10","key":"10.1016\/j.jep.2026.121261_bib14","first-page":"2952","article-title":"Research advances on dihydrofolate reductase inhibitors in the treatment of tumors and bacterial infections","volume":"58","author":"Chen","year":"2023","journal-title":"Acta Pharm. Sin."},{"key":"10.1016\/j.jep.2026.121261_bib15","first-page":"1","article-title":"Role of glucose-6-phosphate dehydrogenase in viral infections","author":"Chen","year":"2024","journal-title":"Prog. Biochem. Biophys."},{"key":"10.1016\/j.jep.2026.121261_bib16","article-title":"Qiguiyin decoction improves multidrug-resistant Pseudomonas aeruginosa infection in rats by regulating inflammatory cytokines and the TLR4\/MyD88\/NF-kappaB signaling pathway","author":"Chen","year":"2022","journal-title":"BioMed Res. Int."},{"issue":"9","key":"10.1016\/j.jep.2026.121261_bib17","first-page":"644","article-title":"Reverse effect of baicalin\/baicalein on antibiotic resistance of methicillin-resistant Staphylococcus aureus","author":"Chen","year":"2008","journal-title":"China Pharm."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib18","first-page":"1","article-title":"Study on resistance of \u03b2-Streptococcus hemolyticus to erythromycin and clindamycin and mechanism of resistance to macrolides","volume":"46","author":"Cheng","year":"2024","journal-title":"J. Shandong Med. Coll."},{"key":"10.1016\/j.jep.2026.121261_bib19","series-title":"Pharmacopoeia of the People's Republic of China","first-page":"445","year":"2020"},{"issue":"10","key":"10.1016\/j.jep.2026.121261_bib21","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1080\/14656566.2025.2519690","article-title":"Tackling multidrug-resistant Gram-negative infections in children globally: current therapeutic options and perspectives","volume":"26","author":"Chiusaroli","year":"2025","journal-title":"Expet Opin. Pharmacother."},{"issue":"10","key":"10.1016\/j.jep.2026.121261_bib22","first-page":"89","article-title":"In vitro inhibition of endotoxin by drug-containing serum of Aloe vera (L.) Burm. f","author":"Cui","year":"2004","journal-title":"Chin. Tradit. Herb. Drugs"},{"issue":"7","key":"10.1016\/j.jep.2026.121261_bib23","first-page":"1110","article-title":"UhpTE350Q mutation along with the presence of fosA6\/5 genes in the genome probably contributes to inherent fosfomycin resistance of Klebsiella pneumoniae","volume":"43","author":"Da","year":"2023","journal-title":"Nan Fang Yi Ke Da Xue Xue Bao"},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib24","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/asia.201901470","article-title":"Synthesis and penicillin-binding protein inhibitory assessment of dipeptidic 4-Phenyl-beta-lactams from alpha-Amino acid-derived imines","volume":"15","author":"Decuyper","year":"2020","journal-title":"Chem. Asian J."},{"issue":"5","key":"10.1016\/j.jep.2026.121261_bib25","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/j.bbapap.2008.11.005","article-title":"Outer membrane permeability and antibiotic resistance","volume":"1794","author":"Delcour","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"issue":"2","key":"10.1016\/j.jep.2026.121261_bib26","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/ja.2013.111","article-title":"A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activity","volume":"67","author":"Deris","year":"2014","journal-title":"J. Antibiot."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib27","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s10096-019-03692-y","article-title":"Cinnamaldehyde: a compound with antimicrobial and synergistic activity against ESBL-producing quinolone-resistant pathogenic enterobacteriaceae","volume":"39","author":"Dhara","year":"2020","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"issue":"9","key":"10.1016\/j.jep.2026.121261_bib28","first-page":"1357","article-title":"Screening of antibacterial activity of 23 Chinese herbal medicines in vitro","volume":"40","author":"Dian","year":"2020","journal-title":"Guihaia"},{"issue":"12","key":"10.1016\/j.jep.2026.121261_bib29","doi-asserted-by":"crossref","first-page":"5952","DOI":"10.1021\/acs.chemrev.8b00277","article-title":"Cell-wall recycling of the gram-negative bacteria and the nexus to antibiotic resistance","volume":"118","author":"Dik","year":"2018","journal-title":"Chem. Rev."},{"key":"10.1016\/j.jep.2026.121261_bib30","series-title":"Intervention of Baicalin Combined with Linezolid on Staphylococcus aureus Biofilm in Vitro and in Vivo. Gaungxi Med","author":"Du","year":"2019"},{"issue":"5","key":"10.1016\/j.jep.2026.121261_bib31","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1080\/07391102.2018.1458654","article-title":"Synergy of clavine alkaloid 'chanoclavine' with tetracycline against multi-drug-resistant E. coli","volume":"37","author":"Dwivedi","year":"2019","journal-title":"J. Biomol. Struct. Dyn."},{"issue":"19","key":"10.1016\/j.jep.2026.121261_bib32","doi-asserted-by":"crossref","first-page":"3351","DOI":"10.1038\/s41388-020-01639-8","article-title":"The functional roles of TCA cycle metabolites in cancer","volume":"40","author":"Eniafe","year":"2021","journal-title":"Oncogene"},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib33","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.phymed.2010.09.003","article-title":"Reversing beta-lactam antibiotic resistance of Staphylococcus aureus with galangin from Alpinia officinarum Hance and synergism with ceftazidime","volume":"18","author":"Eumkeb","year":"2010","journal-title":"Phytomedicine"},{"issue":"20","key":"10.1016\/j.jep.2026.121261_bib34","doi-asserted-by":"crossref","first-page":"4996","DOI":"10.3390\/ijms20204996","article-title":"Folic acid antagonists: antimicrobial and immunomodulating mechanisms and applications","volume":"20","author":"Fern\u00e1ndez-Villa","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib35","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1111\/j.1348-0421.2005.tb03732.x","article-title":"Remarkable synergies between baicalein and tetracycline, and baicalein and beta-lactams against methicillin-resistant Staphylococcus aureus","volume":"49","author":"Fujita","year":"2005","journal-title":"Microbiol. Immunol."},{"key":"10.1016\/j.jep.2026.121261_bib36","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.3389\/fmicb.2015.01544","article-title":"Prevalence of fosfomycin resistance and mutations in murA, glpT, and uhpT in methicillin-resistant Staphylococcus aureus strains isolated from blood and cerebrospinal fluid samples","volume":"6","author":"Fu","year":"2016","journal-title":"Front. Microbiol."},{"issue":"10","key":"10.1016\/j.jep.2026.121261_bib37","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a025395","article-title":"Resistance to macrolide antibiotics in public health pathogens","volume":"6","author":"Fyfe","year":"2016","journal-title":"Cold Spring Harb. Perspect. Med."},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib38","first-page":"307","article-title":"In vitro antibacterial study of three ingredients in sanhuang xiexin decoction combined with antibiotics on Helicobacter pylori","volume":"24","author":"Geng","year":"2021","journal-title":"Pract. Pharm. Clin. Rem."},{"issue":"9","key":"10.1016\/j.jep.2026.121261_bib39","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/ja.2014.107","article-title":"Resistance to rifampicin: a review","volume":"67","author":"Goldstein","year":"2014","journal-title":"J. Antibiot."},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib40","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1093\/jac\/dkn555","article-title":"A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline","volume":"63","author":"Gordon","year":"2009","journal-title":"J. Antimicrob. Chemother."},{"issue":"7","key":"10.1016\/j.jep.2026.121261_bib41","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/s40265-016-0577-0","article-title":"Obiltoxaximab: first global approval","volume":"76","author":"Greig","year":"2016","journal-title":"Drugs"},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib42","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a025387","article-title":"Tetracycline antibiotics and resistance","volume":"6","author":"Grossman","year":"2016","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"10.1016\/j.jep.2026.121261_bib43","series-title":"Study on the Active Constituents from the Root Bark of Morus Alba L. Against drug-resistance Bacteria","author":"Guo","year":"2019"},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib44","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s40360-023-00648-z","article-title":"Glycyrrhetinic acid protects against Multidrug-resistant Acinetobacter baumannii-induced lung epithelial cells injury by regulating inflammation and oxidative stress","volume":"24","author":"Guo","year":"2023","journal-title":"BMC Pharmacol. Toxicol."},{"issue":"22","key":"10.1016\/j.jep.2026.121261_bib45","first-page":"22","article-title":"Observation on the clinical effect of modified puji xiaodu decoction combined with antibiotics on acute tonsillitis","volume":"20","author":"Guo","year":"2022","journal-title":"Chin. Foreign Med. Res."},{"key":"10.1016\/j.jep.2026.121261_bib46","article-title":"Experimental study on the regulation effect of baicalin on the QS system of pseudomonas aeruginosa","author":"Guo","year":"2018","journal-title":"Henan Univ. Chin. Med."},{"issue":"2","key":"10.1016\/j.jep.2026.121261_bib47","doi-asserted-by":"crossref","first-page":"97","DOI":"10.4103\/ijmr.IJMR_755_18","article-title":"Next-generation strategy for treating drug resistant bacteria: antibiotic hybrids","volume":"149","author":"Gupta","year":"2019","journal-title":"Indian J. Med. Res."},{"issue":"11","key":"10.1016\/j.jep.2026.121261_bib48","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.tim.2017.05.011","article-title":"Transfer of antibiotic resistance in Staphylococcus aureus","volume":"25","author":"Haaber","year":"2017","journal-title":"Trends Microbiol."},{"issue":"11","key":"10.1016\/j.jep.2026.121261_bib49","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1080\/15476286.2020.1722449","article-title":"RNA modifications and cancer","volume":"17","author":"Haruehanroengra","year":"2020","journal-title":"RNA Biol."},{"issue":"10","key":"10.1016\/j.jep.2026.121261_bib50","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0140960","article-title":"Within-host and population transmission of blaOXA-48 in K. pneumoniae and E. coli","volume":"10","author":"Haverkate","year":"2015","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib51","first-page":"11","article-title":"Antibacterial activity of flos lonicerae extract to Staphylococcus aureus","volume":"37","author":"He","year":"2013","journal-title":"Guizhou J. Anim. Husbandry Vet. Med."},{"issue":"2","key":"10.1016\/j.jep.2026.121261_bib52","doi-asserted-by":"crossref","first-page":"413","DOI":"10.3390\/biomedicines11020413","article-title":"Nanotechnology as a promising approach to combat multidrug resistant bacteria: a comprehensive review and future perspectives","volume":"11","author":"Hetta","year":"2023","journal-title":"Biomedicines"},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib53","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/nyas.12830","article-title":"Mechanisms of drug resistance: quinolone resistance","volume":"1354","author":"Hooper","year":"2015","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.jep.2026.121261_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2021.107843","article-title":"Traditional chinese medicine (TCM) in the treatment of COVID-19 and other viral infections: efficacies and mechanisms","volume":"225","author":"Huang","year":"2021","journal-title":"Pharmacol. Ther."},{"issue":"23","key":"10.1016\/j.jep.2026.121261_bib55","first-page":"218","article-title":"Antimicrobial resistance of chinese herbal medicine","volume":"24","author":"Huang","year":"2018","journal-title":"Chin. J. Exp. Tradit."},{"issue":"3","key":"10.1016\/j.jep.2026.121261_bib56","first-page":"118","article-title":"Vitro study on the bactericidal effect of Houttuynia cordata thunb. combined with imipenem against carbapenem resistant Pseudomonas aeruginosa","volume":"36","author":"Huang","year":"2021","journal-title":"J. Mod. Lab. Med."},{"issue":"2","key":"10.1016\/j.jep.2026.121261_bib57","first-page":"111","article-title":"Effect of Forsythia suspensa on the adeb gene of the active efflux system of multidrug-resistant Acinetobacter baumannii","volume":"6","author":"Huang","year":"2011","journal-title":"J. Pathog. Biol."},{"issue":"12","key":"10.1016\/j.jep.2026.121261_bib58","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202051034","article-title":"Antibiotic resistance and persistence-Implications for human health and treatment perspectives","volume":"21","author":"Huemer","year":"2020","journal-title":"EMBO Rep."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib59","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/s13065-019-0603-x","article-title":"Design, synthesis, and biological evaluation of novel N4-substituted sulfonamides: acetamides derivatives as dihydrofolate reductase (DHFR) inhibitors","volume":"13","author":"Hussein","year":"2019","journal-title":"BMC chemi"},{"issue":"5","key":"10.1016\/j.jep.2026.121261_bib60","doi-asserted-by":"crossref","first-page":"507","DOI":"10.11150\/kansenshogakuzasshi1970.80.507","article-title":"Mutations of gyrA gene and parC gene in fluoroquinolone-resistant Escherichia coli isolates from sporadic diarrheal cases","volume":"80","author":"Ishiguro","year":"2006","journal-title":"Kansenshogaku Zasshi"},{"issue":"2","key":"10.1016\/j.jep.2026.121261_bib61","doi-asserted-by":"crossref","first-page":"210","DOI":"10.3855\/jidc.17041","article-title":"Emergence of multidrug-resistant ST11 blaKPC-2 producing Klebsiella pneumoniae coharboring blaCTX-M and blaSHV in Pakistan","volume":"17","author":"Jamal Gondal","year":"2023","journal-title":"J. Infect. Dev. Ctries."},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib62","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s13205-024-03950-7","article-title":"Isolation and molecular characterization of multidrug-resistant Escherichia coli from chicken meat","volume":"14","author":"Jaiswal","year":"2024","journal-title":"3 Biotech"},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib63","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/s41392-022-01285-4","article-title":"Ribosome biogenesis in disease: new players and therapeutic targets","volume":"8","author":"Jiao","year":"2023","journal-title":"Signal Transduct. Targeted Ther."},{"issue":"7","key":"10.1016\/j.jep.2026.121261_bib64","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.01974-24","article-title":"Nalidixic acid-a good marker of fluoroquinolone resistance mechanisms in Escherichia coli","volume":"13","author":"Kalinen","year":"2025","journal-title":"Microbiol. Spectr."},{"issue":"12","key":"10.1016\/j.jep.2026.121261_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.jiph.2024.102588","article-title":"Molecular characterization of colistin-resistant Klebsiella pneumoniae isolates and their conjugative mcr-carrying plasmids","volume":"17","author":"Kao","year":"2024","journal-title":"J. Infect. Public Health"},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib66","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1038\/s44259-023-00013-4","article-title":"Di-berberine conjugates as chemical probes of Pseudomonas aeruginosa MexXY-OprM efflux function and inhibition","volume":"1","author":"Kavanaugh","year":"2023","journal-title":"NPJ Antimicrob. Resist."},{"issue":"8","key":"10.1016\/j.jep.2026.121261_bib67","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1099\/mic.0.000313","article-title":"K19 capsular polysaccharide of Acinetobacter baumannii is produced via a Wzy polymerase encoded in a small genomic island rather than the KL19 capsule gene cluster","volume":"162","author":"Kenyon","year":"2016","journal-title":"Microbiology (Read.)"},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib68","first-page":"18","article-title":"Antimicrobial test of Forsythia suspensa (Thunb.) Vahl combined with antimicrobial drugs against multidrug-resistant Escherichia coli B3","author":"Lan","year":"2018","journal-title":"Shanghai J. Anim. Husbandry Vet. Med."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib69","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/s13756-020-00790-x","article-title":"Prevalence of fosfomycin resistance and gene mutations in clinical isolates of methicillin-resistant Staphylococcus aureus","volume":"9","author":"Lee","year":"2020","journal-title":"Antimicrob. Resist. Infect. Control"},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib70","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1093\/jac\/dkr017","article-title":"Artesunate enhances the antibacterial effect of beta-lactam antibiotics against Escherichia coli by increasing antibiotic accumulation via inhibition of the multidrug efflux pump system AcrAB-TolC","volume":"66","author":"Li","year":"2011","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.jep.2026.121261_bib71","article-title":"Carbapenem-resistant Gram-negative bacteria (CR-GNB) in ICUs: resistance genes, therapeutics, and prevention - a comprehensive review","volume":"12","author":"Li","year":"2024","journal-title":"Front. Public Health"},{"issue":"8","key":"10.1016\/j.jep.2026.121261_bib72","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1111\/jcpt.13706","article-title":"Efficacy and safety of tanreqing injection combined with antibiotics against Streptococcus pneumoniae pneumonia: a systematic review and meta-analysis","volume":"47","author":"Li","year":"2022","journal-title":"J. Clin. Pharm. Therapeut."},{"issue":"3","key":"10.1016\/j.jep.2026.121261_bib73","first-page":"97","article-title":"Progress in the study of the mechanism of action and resistance mechanism of quinolone antimicrobials","volume":"36","author":"Li","year":"2015","journal-title":"World Notes Antibiot."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib74","first-page":"238","article-title":"The effects and mechanisms of heat\u2043clearing and detoxifying traditional Chinese medicine on respiratory virus infections in children","volume":"39","author":"Li","year":"2023","journal-title":"Chin. J. Virol."},{"issue":"12","key":"10.1016\/j.jep.2026.121261_bib75","first-page":"165","article-title":"Advances in anti-infective effects of honeysuckle","volume":"57","author":"Li","year":"2019","journal-title":"China Mod. Dr."},{"key":"10.1016\/j.jep.2026.121261_bib77","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110917","article-title":"The main bioactive compounds of Scutellaria baicalensis Georgi. For alleviation of inflammatory cytokines: a comprehensive review","volume":"133","author":"Liao","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2026.121261_bib78","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.158059","article-title":"Removal of chloramphenicol antibiotics in natural and engineered water systems: review of reaction mechanisms and product toxicity","volume":"850","author":"Lin","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jep.2026.121261_bib79","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1146\/annurev-biochem-062917-011942","article-title":"Ribosome-targeting antibiotics: Modes of action, mechanisms of resistance, and implications for drug design","volume":"87","author":"Lin","year":"2018","journal-title":"Rev. Biochem."},{"issue":"15","key":"10.1016\/j.jep.2026.121261_bib80","first-page":"5553","article-title":"Antimicrobial mechanisms of traditional Chinese medicine and reversal of drug resistance: a narrative review","volume":"26","author":"Liu","year":"2022","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"9","key":"10.1016\/j.jep.2026.121261_bib81","first-page":"983","article-title":"Antimicrobial activity of baicalin to Escherichia coli and relevant mechanism","volume":"32","author":"Liu","year":"2019","journal-title":"Chin. J. Biologicals."},{"issue":"2","key":"10.1016\/j.jep.2026.121261_bib82","first-page":"207","article-title":"Effect of broadleaf holly leaf and thymifolious euphorbia herb on efflux pumps acrA gene expression of multidrug-resistant Escherichia coli","volume":"38","author":"Liu","year":"2016","journal-title":"Guangxi Med. J."},{"key":"10.1016\/j.jep.2026.121261_bib83","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/s41420-018-0029-6","article-title":"Magnolol restores the activity of meropenem against NDM-1-producing Escherichia coli by inhibiting the activity of metallo-beta-lactamase","volume":"4","author":"Liu","year":"2018","journal-title":"Cell Death Discov."},{"key":"10.1016\/j.jep.2026.121261_bib84","volume":"147","author":"Liu","year":"2020"},{"key":"10.1016\/j.jep.2026.121261_bib85","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.118365","article-title":"Fuzheng touxie jiedu huayu decoction inhibits the MexAB-OprM efflux pump and quorum sensing-mediated biofilm formation in difficult-to-treat multidrug resistance Pseudomonas aeruginosa","volume":"332","author":"Liu","year":"2024","journal-title":"J. Ethnopharmacol."},{"issue":"12","key":"10.1016\/j.jep.2026.121261_bib86","first-page":"1018","article-title":"Antibacterial and NDM-1 plasmid elimination effects of Radix scutellariae baicalensis on Acinetobacter calcoaceticus","volume":"52","author":"Liu","year":"2017","journal-title":"Chin. Pharmaceut. J."},{"key":"10.1016\/j.jep.2026.121261_bib87","doi-asserted-by":"crossref","first-page":"183","DOI":"10.2147\/DDDT.S97221","article-title":"Baicalein attenuates the quorum sensing-controlled virulence factors of Pseudomonas aeruginosa and relieves the inflammatory response in P. Aeruginosa-infected macrophages by downregulating the MAPK and NFkappaB signal-transduction pathways","volume":"10","author":"Luo","year":"2016","journal-title":"Drug Des. Dev. Ther."},{"issue":"3","key":"10.1016\/j.jep.2026.121261_bib88","first-page":"15","article-title":"Characteristics of infection distribution of KPC-producing klebsiella pneumoniae and its inhibitory effect on integrated traditional Chinese medicine and western medicine","volume":"56","author":"Lu","year":"2018","journal-title":"Chin. Mod. Doctor"},{"key":"10.1016\/j.jep.2026.121261_bib89","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/1488141","article-title":"In Vitro antibacterial experiments of qixingjian decoction and its synergistic interaction with oxacillin against clinical isolates of methicillin-resistant Staphylococcus aureus","volume":"2022","author":"Lv","year":"2022","journal-title":"Evid. Based Complement. Alternat. Med."},{"issue":"8","key":"10.1016\/j.jep.2026.121261_bib90","first-page":"2023","article-title":"Network Meta-analysis of Chinese patent medicines combined with antibiotics in treatment of pelvic inflammatory diseases","volume":"49","author":"Ma","year":"2024","journal-title":"China J. Chin. Mater. Med."},{"issue":"2","key":"10.1016\/j.jep.2026.121261_bib91","first-page":"38","article-title":"In-vivo and In-vitro antimicrobial effects of Coptis chinensis franch. And Rheum officinale Baill. in combination with ceftazidime","author":"Mao","year":"2006","journal-title":"Pharmacol. Clin. Chin. Mater."},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib92","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1111\/cbdd.12103","article-title":"Antibacterial and synergy of clavine alkaloid lysergol and its derivatives against nalidixic acid-resistant Escherichia coli","volume":"81","author":"Maurya","year":"2013","journal-title":"Chem. Biol. Drug Des."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib93","doi-asserted-by":"crossref","first-page":"92","DOI":"10.3390\/genes11010092","article-title":"Mapping DNA topoisomerase binding and cleavage genome wide using next-generation sequencing techniques","volume":"11","author":"Mckie","year":"2020","journal-title":"Genes"},{"key":"10.1016\/j.jep.2026.121261_bib94","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.2147\/IDR.S177886","article-title":"Molecular detection of vanA and vanB genes among vancomycin-resistant enterococci in ICU-hospitalized patients in Ahvaz in southwest of Iran","volume":"11","author":"Moosavian","year":"2018","journal-title":"Infect. Drug Resist."},{"issue":"12","key":"10.1016\/j.jep.2026.121261_bib95","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1016\/j.str.2009.10.013","article-title":"Structure and mechanism of the lincosamide antibiotic adenylyltransferase LinB","volume":"17","author":"Morar","year":"2009","journal-title":"Structure"},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib96","doi-asserted-by":"crossref","DOI":"10.1128\/ecosalplus.esp-0017-2019","article-title":"Inhibition of RNA polymerase by rifampicin and rifamycin-like molecules","volume":"9","author":"Mosaei","year":"2020","journal-title":"EcoSal Plus"},{"issue":"9","key":"10.1016\/j.jep.2026.121261_bib97","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1089\/mdr.2024.0099","article-title":"Bioflavonoid baicalein modulates tetracycline resistance by inhibiting efflux pump in Staphylococcus aureus","volume":"30","author":"Moulick","year":"2024","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.jep.2026.121261_bib98","doi-asserted-by":"crossref","DOI":"10.1016\/j.onehlt.2025.101054","article-title":"Genomic analysis elucidates characteristics and possible origins of high-risk antimicrobial resistance genes in Enterococcus faecium from a global perspective","volume":"20","author":"Mu","year":"2025","journal-title":"One Health"},{"issue":"8","key":"10.1016\/j.jep.2026.121261_bib99","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1007\/s11274-025-04508-2","article-title":"The antibacterial activity, action mechanisms and prospects of baicalein as an antibacterial adjuvant","volume":"41","author":"Mu","year":"2025","journal-title":"World J. Microbiol. Biotechnol."},{"issue":"8\u20139","key":"10.1016\/j.jep.2026.121261_bib100","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.phymed.2013.02.006","article-title":"Synergistic antibacterial effect of curcumin against methicillin-resistant Staphylococcus aureus","volume":"20","author":"Mun","year":"2013","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2026.121261_bib101","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetmic.2024.110319","article-title":"Genomic analyses of Streptococcus uberis reveal high diversity but few antibiotic resistance genes","volume":"300","author":"Myren\u00e5s","year":"2025","journal-title":"Vet. Microbiol."},{"issue":"2","key":"10.1016\/j.jep.2026.121261_bib102","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijantimicag.2021.106505","article-title":"Polymyxin causes cell envelope remodelling and stress responses in mcr-1-harbouring Escherichia coli","volume":"59","author":"Nang","year":"2022","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.jep.2026.121261_bib103","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1146\/annurev.biochem.78.082907.145923","article-title":"Multidrug resistance in bacteria","volume":"78","author":"Nikaido","year":"2009","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.jep.2026.121261_bib104","doi-asserted-by":"crossref","DOI":"10.1016\/j.job.2025.100679","article-title":"Complete genome sequence of a tetracycline-resistant Streptococcus mutans strain carrying the tet(M) gene","author":"Nishihama","year":"2025","journal-title":"J. Oral Biosci."},{"issue":"12","key":"10.1016\/j.jep.2026.121261_bib105","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.3390\/antibiotics12121746","article-title":"Strategies to name Metallo-\u03b2-Lactamases and number their amino acid residues","volume":"12","author":"Oelschlaeger","year":"2023","journal-title":"Antibiotics (Basel)"},{"issue":"5","key":"10.1016\/j.jep.2026.121261_bib106","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1007\/s10096-015-2323-z","article-title":"Biofilm-specific antibiotic tolerance and resistance","volume":"34","author":"Olsen","year":"2015","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"issue":"3","key":"10.1016\/j.jep.2026.121261_bib107","doi-asserted-by":"crossref","first-page":"295","DOI":"10.3390\/antibiotics14030295","article-title":"Multiplex real-time polymerase chain reaction and recombinase polymerase amplification: methods for quick and cost-effective detection of vancomycin-resistant enterococci (VRE)","volume":"14","author":"Osadare","year":"2025","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.jep.2026.121261_bib108","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.737252","article-title":"Traditional Chinese medicine is an alternative therapeutic option for treatment of Pseudomonas aeruginosa infections","volume":"12","author":"Pang","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.121261_bib109","doi-asserted-by":"crossref","DOI":"10.1038\/srep15573","article-title":"Genetic analysis of capsular polysaccharide synthesis gene clusters in 79 capsular types of Klebsiella spp","volume":"5","author":"Pan","year":"2015","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib110","doi-asserted-by":"crossref","DOI":"10.1128\/CMR.00088-17","article-title":"Mobile genetic elements associated with antimicrobial resistance","volume":"31","author":"Partridge","year":"2018","journal-title":"Clin. Microbiol. Rev."},{"issue":"12","key":"10.1016\/j.jep.2026.121261_bib111","doi-asserted-by":"crossref","first-page":"2436","DOI":"10.3390\/microorganisms9122436","article-title":"Klebsiella pneumoniae complex harboring mcr-1, mcr-7, and mcr-8 isolates from slaughtered pigs in Thailand","volume":"9","author":"Phetburom","year":"2021","journal-title":"Microorganisms"},{"issue":"3","key":"10.1016\/j.jep.2026.121261_bib112","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s00604-024-06224-4","article-title":"Progress of ligand-modified agarose microspheres for protein isolation and purification","volume":"191","author":"Qi","year":"2024","journal-title":"Mikrochim. Acta"},{"key":"10.1016\/j.jep.2026.121261_bib113","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.117488","article-title":"Revealing active constituents within traditional Chinese medicine used for treating bacterial pneumonia, with emphasis on the mechanism of baicalein against multi-drug resistant Klebsiella pneumoniae","volume":"321","author":"Qin","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121261_bib114","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1128\/CMR.00001-07","article-title":"Carbapenemases: the versatile beta-lactamases","volume":"20","author":"Queenan","year":"2007","journal-title":"Clin. Microbiol. Rev."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib115","doi-asserted-by":"crossref","first-page":"4224","DOI":"10.1038\/s41598-019-39730-0","article-title":"blaCTX-M variants and genotype-phenotype correlations among clinical isolates of extended spectrum beta lactamase-producing Escherichia coli","volume":"9","author":"Ramadan","year":"2019","journal-title":"Sci. Rep."},{"issue":"5","key":"10.1016\/j.jep.2026.121261_bib116","first-page":"43","article-title":"Effect of Chinese traditional medicine weeping Forsythia on multidrug resistance gene AcrA of the E. coli","author":"Ren","year":"2008","journal-title":"Prog. Vet. Med."},{"issue":"18","key":"10.1016\/j.jep.2026.121261_bib117","first-page":"150","article-title":"Study on effects of three honeysuckle extracts against bacterial endotoxin","author":"Ren","year":"2022","journal-title":"Mod. Agric. Sci. Technol."},{"key":"10.1016\/j.jep.2026.121261_bib118","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1146\/annurev-micro-020518-120056","article-title":"Growth and division of the peptidoglycan matrix","volume":"75","author":"Rohs","year":"2021","journal-title":"Annu. Rev. Microbiol."},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib119","doi-asserted-by":"crossref","first-page":"560","DOI":"10.3855\/jidc.18973","article-title":"Genetic characterization of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae collected from healthy turkeys","volume":"19","author":"Romdhani","year":"2025","journal-title":"J. Infect. Dev. Ctries."},{"issue":"7","key":"10.1016\/j.jep.2026.121261_bib120","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a027011","article-title":"Rifamycins, alone and in combination","volume":"6","author":"Rothstein","year":"2016","journal-title":"Cold Spring Harb. Perspect. Med."},{"issue":"9","key":"10.1016\/j.jep.2026.121261_bib121","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.3390\/antibiotics12091376","article-title":"Detection and phylogenetic analysis of extended-spectrum beta-lactamase (ESBL)-genetic determinants in gram-negative fecal-microbiota of wild birds and chicken originated at trimmu barrage","volume":"12","author":"Saeed","year":"2023","journal-title":"Antibiotics (Basel)"},{"issue":"18","key":"10.1016\/j.jep.2026.121261_bib122","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1055\/s-0042-114781","article-title":"Glycyrrhizic acid decreases gentamicin-resistance in vancomycin-resistant enterococci","volume":"82","author":"Schmidt","year":"2016","journal-title":"Planta Med."},{"issue":"11","key":"10.1016\/j.jep.2026.121261_bib123","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a027037","article-title":"Lincosamides, streptogramins, phenicols, and pleuromutilins: mode of action and mechanisms of resistance","volume":"6","author":"Schwarz","year":"2016","journal-title":"Cold Spring Harb. Perspect. Med."},{"issue":"5","key":"10.1016\/j.jep.2026.121261_bib124","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.00160-20","article-title":"The novel macrolide resistance genes mef(D), msr(F), and msr(H) are present on resistance islands in macrococcus canis, Macrococcus caseolyticus, and Staphylococcus aureus","volume":"64","author":"Schwendener","year":"2020","journal-title":"Antimicrob. Agents Chemother."},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib125","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1128\/AAC.05325-11","article-title":"MupB, a new high-level mupirocin resistance mechanism in Staphylococcus aureus","volume":"56","author":"Seah","year":"2012","journal-title":"Antimicrob. Agents Chemother."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib126","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-25226-x","article-title":"The role of pmrCAB genes in colistin-resistant Acinetobacter baumannii","volume":"12","author":"Seleim","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2026.121261_bib127","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s13756-019-0533-3","article-title":"Antibiotics versus biofilm: an emerging battleground in microbial communities","volume":"8","author":"Sharma","year":"2019","journal-title":"Antimicrob. Resist. Infect. Control"},{"key":"10.1016\/j.jep.2026.121261_bib128","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.156038","article-title":"Antibacterial effect and mechanisms of action of forsythoside B, alone and in combination with antibiotics, against Acinetobacter baumannii and Pseudomonas aeruginosa","volume":"135","author":"Shi","year":"2024","journal-title":"Phytomedicine"},{"issue":"2","key":"10.1016\/j.jep.2026.121261_bib129","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a025262","article-title":"Fosfomycin: mechanism and resistance","volume":"7","author":"Silver","year":"2017","journal-title":"Cold Spring Harb. Perspect. Med."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib130","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.00951-20","article-title":"Cefiderocol antimicrobial susceptibility testing considerations: the achilles' heel of the trojan horse?","volume":"59","author":"Simner","year":"2020","journal-title":"J. Clin. Microbiol."},{"issue":"6","key":"10.1016\/j.jep.2026.121261_bib131","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1128\/AAC.46.6.1845-1850.2002","article-title":"An Enterococcus faecalis ABC homologue (Lsa) is required for the resistance of this species to clindamycin and quinupristin-dalfopristin","volume":"46","author":"Singh","year":"2002","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jep.2026.121261_bib132","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2025.1553681","article-title":"Detection assay of polymyxin resistance coding mcr-1 gene based on CRISPR\/Cas13a system","volume":"15","author":"Song","year":"2025","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"9","key":"10.1016\/j.jep.2026.121261_bib133","doi-asserted-by":"crossref","first-page":"534","DOI":"10.3390\/antibiotics9090534","article-title":"Characterization of fosfomycin and nitrofurantoin resistance mechanisms in Escherichia coli isolated in clinical urine samples","volume":"9","author":"Sorlozano-Puerto","year":"2020","journal-title":"Antibiotics (Basel)"},{"issue":"9","key":"10.1016\/j.jep.2026.121261_bib134","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1086\/420937","article-title":"Trends in antimicrobial drug development: implications for the future","volume":"38","author":"Spellberg","year":"2004","journal-title":"Clin. Infect. Dis."},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib135","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/s00253-003-1545-7","article-title":"Lincomycin, clindamycin and their applications","volume":"64","author":"Sp\u00edzek","year":"2004","journal-title":"Appl. Microbiol. Biotechnol."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib136","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s13568-019-0750-4","article-title":"Ursolic acid inhibits colistin efflux and curtails colistin resistant enterobacteriaceae","volume":"9","author":"Sundaramoorthy","year":"2019","journal-title":"AMB Express"},{"issue":"3","key":"10.1016\/j.jep.2026.121261_bib137","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.jmii.2022.02.001","article-title":"Recommendations and guidelines for the treatment of infections due to multidrug resistant organisms","volume":"55","author":"Sy","year":"2022","journal-title":"J. Microbiol. Immunol. Infect."},{"issue":"2","key":"10.1016\/j.jep.2026.121261_bib138","first-page":"573","article-title":"In vitro antimicrobial effects of carvacrol combined with ceftriaxone on drug-resistant Salmonella","volume":"50","author":"Tang","year":"2023","journal-title":"Microbiol. China"},{"key":"10.1016\/j.jep.2026.121261_bib139","article-title":"Synthesis and antibacterial mechanism study of pogostone and its analogues","author":"Tang","year":"2016","journal-title":"Chengdu Univ. Tradit. Chin. Med."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib140","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s12929-014-0090-2","article-title":"Synergistic activity and mechanism of action of Stephania suberosa Forman extract and ampicillin combination against ampicillin-resistant Staphylococcus aureus","volume":"21","author":"Teethaisong","year":"2014","journal-title":"J. Biomed. Sci."},{"issue":"10","key":"10.1016\/j.jep.2026.121261_bib141","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01081-19","article-title":"Cinnamaldehyde induces expression of efflux pumps and multidrug resistance in Pseudomonas aeruginosa","volume":"63","author":"Tetard","year":"2019","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.jep.2026.121261_bib142","series-title":"Antibacteria Effects of Gallic Acid Combined with Antibiotics Against Multidrug Resistant Escherichia coli","author":"Tian","year":"2023"},{"issue":"10","key":"10.1016\/j.jep.2026.121261_bib143","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.3390\/ph16101371","article-title":"Multitargeted herbal prescription so shiho tang: a scoping review on biomarkers for the evaluation of therapeutic effects","volume":"16","author":"Tran","year":"2023","journal-title":"Pharmaceuticals"},{"issue":"5","key":"10.1016\/j.jep.2026.121261_bib144","doi-asserted-by":"crossref","DOI":"10.1128\/aac.01699-24","article-title":"Spectrum of cefepime-taniborbactam coverage against 190 \u03b2-lactamases defined in engineered isogenic Escherichia coli strains","volume":"69","author":"Uehara","year":"2025","journal-title":"Antimicrob. Agents Chemother."},{"issue":"11","key":"10.1016\/j.jep.2026.121261_bib145","doi-asserted-by":"crossref","first-page":"4673","DOI":"10.1128\/AAC.00853-09","article-title":"Two distinct major facilitator superfamily drug efflux pumps mediate chloramphenicol resistance in Streptomyces coelicolor","volume":"53","author":"Vecchione","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"issue":"5","key":"10.1016\/j.jep.2026.121261_bib146","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1021\/jm900999h","article-title":"Structure-activity relationships of polymyxin antibiotics","volume":"53","author":"Velkov","year":"2010","journal-title":"J. Med. Chem."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib147","doi-asserted-by":"crossref","first-page":"4031","DOI":"10.1038\/s41467-023-39778-7","article-title":"Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics","volume":"14","author":"Venkatesan","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jep.2026.121261_bib148","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2021.101316","article-title":"From DNA damage to mutations: all roads lead to aging","volume":"68","author":"Vijg","year":"2021","journal-title":"Ageing Res. Rev."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib149","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/s41569-022-00737-2","article-title":"Gut-derived low-grade endotoxaemia, atherothrombosis and cardiovascular disease","volume":"20","author":"Violi","year":"2023","journal-title":"Nat. Rev. Cardiol."},{"issue":"12","key":"10.1016\/j.jep.2026.121261_bib150","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0112726","article-title":"Garlic revisited: antimicrobial activity of allicin-containing garlic extracts against Burkholderia cepacia complex","volume":"9","author":"Wallock-Richards","year":"2014","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.jep.2026.121261_bib151","first-page":"1376","article-title":"Antibacterial activity and mechanism of essential oil from Pogostemon cablin against Staphylococcus aureus","volume":"36","author":"Wan","year":"2014","journal-title":"Chin. Tradit. Pat. Med."},{"key":"10.1016\/j.jep.2026.121261_bib152","first-page":"400","article-title":"Experimental study of baicalin curing antibiotic-resistant plasmid in Acinetobacter baumanii","volume":"29","author":"Wang","year":"2012","journal-title":"Chin. J. Mod. Appl. Pharm."},{"key":"10.1016\/j.jep.2026.121261_bib153","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcis.2025.137593","article-title":"Quercetin sensitized covalent organic framework for boosting photocatalytic H2O2 production and antibacterial","volume":"693","author":"Wang","year":"2025","journal-title":"J. Colloid Interface Sci."},{"issue":"10","key":"10.1016\/j.jep.2026.121261_bib154","first-page":"143","article-title":"Combined antibiotic and traditional Chinese medicine inhibition test on Bacillus cereus","author":"Wang","year":"2017","journal-title":"Helongjiang Anim. Sci. Vet. Med."},{"issue":"2","key":"10.1016\/j.jep.2026.121261_bib155","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1007\/s00253-018-9482-7","article-title":"Chlorogenic acid attenuates virulence factors and pathogenicity of Pseudomonas aeruginosa by regulating quorum sensing","volume":"103","author":"Wang","year":"2019","journal-title":"Appl. Microbiol. Biotechnol."},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib156","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.apsb.2015.05.005","article-title":"The antiviral and antimicrobial activities of licorice, a widely-used Chinese herb","volume":"5","author":"Wang","year":"2015","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.jep.2026.121261_bib157","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2022.997310","article-title":"Effects of chlorogenic acid on antimicrobial, antivirulence, and anti-quorum sensing of carbapenem-resistant Klebsiella pneumoniae","volume":"13","author":"Wang","year":"2022","journal-title":"Front. Microbiol."},{"issue":"3","key":"10.1016\/j.jep.2026.121261_bib158","first-page":"649","article-title":"Clinical study of danshu capsules combined with ceftriaxone in treatment of chronic cholecystitis","volume":"38","author":"Wang","year":"2023","journal-title":"Mod. Drug Discov."},{"issue":"6","key":"10.1016\/j.jep.2026.121261_bib159","first-page":"807","article-title":"Effects of fuzheng tongxie jiedu Huayu formula on inflammation and immune function in elderly pneumonia rats at different time points","volume":"19","author":"Wang","year":"2024","journal-title":"World Chin. Med."},{"key":"10.1016\/j.jep.2026.121261_bib160","series-title":"Study on the Inhibitory Effect of Safranin Combined with Ceftazidime on ultra-broad-spectrum beta-lactamase-producing Escherichia coli Bacteria","author":"Wang","year":"2005"},{"issue":"31","key":"10.1016\/j.jep.2026.121261_bib161","first-page":"150","article-title":"Clinical effect of traditional Chinese medicine preparation \"Pneumonia No.1 Mixture\" combined with antibiotics on children's community acquired pneumonia. China Mod","volume":"28","author":"Wei","year":"2021","journal-title":"M\u00e9d. Sur"},{"key":"10.1016\/j.jep.2026.121261_bib162","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115748","article-title":"Traditional Chinese medicine has great potential as candidate drugs for lung cancer: a review","volume":"300","author":"Wei","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib163","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/nrmicro3155","article-title":"Ribosome-targeting antibiotics and mechanisms of bacterial resistance","volume":"12","author":"Wilson","year":"2014","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.jep.2026.121261_bib164","article-title":"'Omics technologies for the elucidation of the molecular mechanisms related to carbapenem-resistant and extended spectrum \u03b2-lactamase-producing Klebsiella pneumoniae","volume":"296","author":"Woodland","year":"2025","journal-title":"Talanta"},{"issue":"6684","key":"10.1016\/j.jep.2026.121261_bib165","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1126\/science.adk8013","article-title":"An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance","volume":"383","author":"Wu","year":"2024","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.jep.2026.121261_bib166","doi-asserted-by":"crossref","first-page":"799","DOI":"10.3390\/antibiotics11060799","article-title":"Prevalence and molecular characteristics of polymyxin-resistant Pseudomonas aeruginosa in a Chinese tertiary teaching hospital","volume":"11","author":"Xiao","year":"2022","journal-title":"Antibiotics (Basel)"},{"issue":"11","key":"10.1016\/j.jep.2026.121261_bib167","first-page":"1563","article-title":"Progress in the study of the chemical composition and pharmacological effects of Houttuynia cordata Thunb","volume":"31","author":"Xiao","year":"2022","journal-title":"Mod. J. Integr. Tradit. Chin. West. Med."},{"key":"10.1016\/j.jep.2026.121261_bib168","article-title":"Effects and mechanism of tanreqing on cell division of Methicillin-resistant staphylococus aureus. China acad","author":"Xing","year":"2020","journal-title":"Chin. Med. Sci."},{"issue":"6","key":"10.1016\/j.jep.2026.121261_bib169","first-page":"84","article-title":"Clinical effect of traditional Chinese medicine combined with antibiotics in the treatment of acute severe pneumonia. Inner Mong","volume":"41","author":"Xing","year":"2022","journal-title":"J. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2026.121261_bib170","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.3389\/fphar.2019.01682","article-title":"In vitro antibacterial experiment of fuzheng Jiedu Huayu decoction against multidrug-resistant Pseudomonas aeruginosa","volume":"10","author":"Xu","year":"2020","journal-title":"Front. Pharmacol."},{"issue":"19","key":"10.1016\/j.jep.2026.121261_bib171","first-page":"154","article-title":"Studies on the elimination of three bacterial R plasmids by a single Chinese medicine","author":"Yang","year":"2014","journal-title":"Helongjiang Anim. Sci. Vet."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib172","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/s41429-024-00778-4","article-title":"Resistance to linezolid in Staphylococcus aureus by mutation, modification, and acquisition of genes","volume":"78","author":"Yang","year":"2025","journal-title":"J. Antibiot."},{"key":"10.1016\/j.jep.2026.121261_bib173","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2025.109499","article-title":"Unraveling the evolution and global transmission of high level tigecycline resistance gene tet(X)","volume":"199","author":"Yao","year":"2025","journal-title":"Environ. Int."},{"issue":"4","key":"10.1016\/j.jep.2026.121261_bib174","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1128\/AAC.45.4.1151-1161.2001","article-title":"Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae","volume":"45","author":"Yigit","year":"2001","journal-title":"Antimicrob. Agents Chemother."},{"issue":"6","key":"10.1016\/j.jep.2026.121261_bib175","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1080\/1120009X.2020.1735118","article-title":"Alterations in AdeS and AdeR regulatory proteins in 1-(1-naphthylmethyl)-piperazine responsive colistin resistance of Acinetobacter baumannii","volume":"32","author":"Yilmaz","year":"2020","journal-title":"J. Chemother."},{"issue":"2","key":"10.1016\/j.jep.2026.121261_bib176","doi-asserted-by":"crossref","first-page":"361","DOI":"10.3390\/microorganisms13020361","article-title":"Antibiotic resistance profiles and genomic analysis of endophytic bacteria isolates from wild edible fungi in Yunnan","volume":"13","author":"Yi","year":"2025","journal-title":"Microorganisms"},{"key":"10.1016\/j.jep.2026.121261_bib177","first-page":"79","article-title":"The research of the experiment of tanreqing for the effect of acinetobacter spp efflux pump genes adeB","volume":"6","author":"Yi","year":"2014","journal-title":"Clin. J. Chin. Med."},{"key":"10.1016\/j.jep.2026.121261_bib178","first-page":"93","article-title":"Observation on effect of combined Sanjin tablets and antibiotic on female urinary tract infection after sex life","volume":"25","author":"Yu","year":"2010","journal-title":"China J. Tradit. Chin. Med."},{"issue":"8","key":"10.1016\/j.jep.2026.121261_bib179","first-page":"1907","article-title":"A retrospective study on the preventive occurrence and prognosis of drug-resistant bacterial infections in severe pneumonia associated with traditional Chinese medicine treatment","volume":"31","author":"Yuan","year":"2020","journal-title":"Lishizhen Med. Mater. Medica. Res."},{"issue":"12","key":"10.1016\/j.jep.2026.121261_bib180","first-page":"1587","article-title":"Antibacterial activity and mechanism of baicalein","volume":"47","author":"Yun","year":"2012","journal-title":"Acta Pharm. Sin."},{"issue":"12","key":"10.1016\/j.jep.2026.121261_bib181","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a026989","article-title":"Approved glycopeptide antibacterial drugs: mechanism of action and resistance","volume":"6","author":"Zeng","year":"2016","journal-title":"Cold Spring Harb. Perspect. Med."},{"issue":"5","key":"10.1016\/j.jep.2026.121261_bib182","first-page":"1727","article-title":"Combined antibacterial action and mechanism of antibiotics and traditional Chinese medicine on Escherichia coli","volume":"42","author":"Zeng","year":"2023","journal-title":"Environ. Chem."},{"issue":"5","key":"10.1016\/j.jep.2026.121261_bib183","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3390\/diseases13050154","article-title":"Curcumin reverses antibiotic resistance and downregulates Shiga toxin expression in enterohemorrhagic E. coli","volume":"13","author":"Zerme\u00f1o-Ruiz","year":"2025","journal-title":"Diseases"},{"issue":"9","key":"10.1016\/j.jep.2026.121261_bib184","first-page":"656","article-title":"Mechanism of action and material basis of active ingredients in Chinese medicine","volume":"33","author":"Zhang","year":"2019","journal-title":"Chin. J. Pharmacol. Toxicol."},{"issue":"2","key":"10.1016\/j.jep.2026.121261_bib185","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1631\/jzus.C1200195","article-title":"The analysis of the treatment of epidemic diseases of TCM during the Qin and Han dynasties","volume":"37","author":"Zhang","year":"2013","journal-title":"J. Zhejiang Chin. Med. Univ."},{"key":"10.1016\/j.jep.2026.121261_bib186","series-title":"Clinical Observation on Modified Zhenwu Decoction Combined with Antibiotics in Treating Chronic Pyelonephritis with Yang Deficiency of Spleen and Kidney","author":"Zhang","year":"2021"},{"issue":"2","key":"10.1016\/j.jep.2026.121261_bib187","first-page":"469","article-title":"Study on antibacterial activity and mechanism of selenium glycyrrhiza polysaccharide, glycyrrhiza polysaccharide and their combined antibiotics against Streptococcus agalactiae in vitro","volume":"61","author":"Zhang","year":"2024","journal-title":"Xinjiang Agric. Sci."},{"key":"10.1016\/j.jep.2026.121261_bib188","article-title":"Antibacterial activity mechanism of coptisine against Pasteurella multocida","volume":"13","author":"Zhang","year":"2023","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.jep.2026.121261_bib189","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jgar.2019.08.006","article-title":"Molecular mechanisms and epidemiology of fosfomycin resistance in enterococci isolated from patients at a teaching hospital in China, 2013-2016","volume":"20","author":"Zhang","year":"2020","journal-title":"J. Glob. Antimicrob. Resist."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib190","first-page":"122","article-title":"Studies on the chemical composition of the fibrous roots of Coptis chinensis Franch","volume":"44","author":"Zhao","year":"2022","journal-title":"Chin. Tradit. Pat. Med."},{"key":"10.1016\/j.jep.2026.121261_bib191","series-title":"The Components Analysis and Research on Antibaceria Activity of the Fibre of Coptis chinensis Franch","author":"Zheng","year":"2009"},{"issue":"11","key":"10.1016\/j.jep.2026.121261_bib192","first-page":"117","article-title":"Clinical value of Tanreqing combined with antibiotics in the treatment of pulmonary tuberculosis complicated by infection","volume":"17","author":"Zheng","year":"2023","journal-title":"Chin. J. Mod. Drug Appl."},{"issue":"1","key":"10.1016\/j.jep.2026.121261_bib193","first-page":"141","article-title":"Progress in the study of chemical composition and pharmacological effects of Scutellaria baicalensis Georgi","volume":"38","author":"Zheng","year":"2016","journal-title":"Chin. Tradit. Pat. Med."},{"key":"10.1016\/j.jep.2026.121261_bib194","first-page":"1377","article-title":"Antimicrobial effect of Huanglian Jiedu decoction combined with antibiotics on methicillin resistant Staphylococcus aureus in vitro","volume":"41","author":"Zhou","year":"2021","journal-title":"Chin. J. Integr. Tradit. West. Med."},{"key":"10.1016\/j.jep.2026.121261_bib195","doi-asserted-by":"crossref","first-page":"7313","DOI":"10.2147\/IDR.S431256","article-title":"Potentiation and mechanism of berberine as an antibiotic adjuvant against multidrug-resistant bacteria","volume":"16","author":"Zhou","year":"2023","journal-title":"Infect. Drug Resist."},{"issue":"12","key":"10.1016\/j.jep.2026.121261_bib196","first-page":"1156","article-title":"Antibacterial mechanism of emodin on Staphylococcus aureus","volume":"27","author":"Zhou","year":"2011","journal-title":"Chin. J. Biochem. Mol."},{"issue":"3","key":"10.1016\/j.jep.2026.121261_bib197","first-page":"228","article-title":"Antimicrobial mechanisms of 3-O-caffeoyl quinic acid and 3,5-di-O-caffeoyl quinic acid against Escherichia coli","volume":"39","author":"Zhou","year":"2014","journal-title":"Food Sci. Technol."},{"issue":"9","key":"10.1016\/j.jep.2026.121261_bib198","first-page":"575","article-title":"Hongteng decoction combined with antibiotic therapy for treatment of periappendiceal abscess: therapeutic effect and possible immune mechanism","volume":"26","author":"Zhu","year":"2018","journal-title":"World J. Gastroenterol."},{"issue":"3","key":"10.1016\/j.jep.2026.121261_bib199","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/s12016-021-08919-5","article-title":"Road less traveled: drug hypersensitivity to fluoroquinolones, Vancomycin, tetracyclines, and macrolides","volume":"62","author":"Zhu","year":"2022","journal-title":"Clin. Rev. Allergy Immunol."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126001121?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126001121?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T16:28:13Z","timestamp":1776184093000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874126001121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":195,"alternative-id":["S0378874126001121"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2026.121261","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Potential of traditional Chinese medicine-antibiotic combinations in combating multidrug-resistant organisms: Advances, mechanisms, and clinical implications","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2026.121261","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"121261"}}