{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T17:22:22Z","timestamp":1776187342605,"version":"3.50.1"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100019033","name":"Key Research and Development Program of Liaoning Province","doi-asserted-by":"publisher","award":["2024JH2\/102500062"],"award-info":[{"award-number":["2024JH2\/102500062"]}],"id":[{"id":"10.13039\/501100019033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005047","name":"Liaoning Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["2025-MSLH-490"],"award-info":[{"award-number":["2025-MSLH-490"]}],"id":[{"id":"10.13039\/501100005047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82104838"],"award-info":[{"award-number":["82104838"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.jep.2026.121286","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T18:59:20Z","timestamp":1769713160000},"page":"121286","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["A study on the network pharmacology of HQGZWWT that prevents CINP by inhibiting ferroptosis through regulation of the p38\/c-FOS\/NF-kB pathway"],"prefix":"10.1016","volume":"364","author":[{"given":"Mingzhu","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenshun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengbo","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuxin","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huini","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingxue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengfei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haozhe","family":"Piao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.jep.2026.121286_bib1","doi-asserted-by":"crossref","DOI":"10.3390\/biom15060874","article-title":"Unraveling osteoarthritis: mechanistic insights and emerging therapies targeting pain and inflammation","volume":"15","author":"Alad","year":"2025","journal-title":"Biomolecules"},{"key":"10.1016\/j.jep.2026.121286_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.neulet.2023.137367","article-title":"Nanoliposomal oxaliplatin ameliorates chemotherapy-induced neuropathy","volume":"812","author":"Alaei","year":"2023","journal-title":"Neurosci. Lett."},{"issue":"2","key":"10.1016\/j.jep.2026.121286_bib3","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.jphs.2022.12.004","article-title":"Repeated topical paeoniflorin attenuates postoperative pain and accelerates cutaneous fibroblast proliferation in mice","volume":"151","author":"Andoh","year":"2023","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.jep.2026.121286_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.phymed.2016.12.010","article-title":"Prophylactic topical paeoniflorin prevents mechanical allodynia caused by paclitaxel in mice through adenosine A(1) receptors","volume":"25","author":"Andoh","year":"2017","journal-title":"Phytomedicine"},{"issue":"11","key":"10.1016\/j.jep.2026.121286_bib5","doi-asserted-by":"crossref","DOI":"10.1063\/5.0020514","article-title":"Pressure control using stochastic cell rescaling","volume":"153","author":"Bernetti","year":"2020","journal-title":"J. Chem. Phys."},{"issue":"1","key":"10.1016\/j.jep.2026.121286_bib6","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.ygyno.2015.11.011","article-title":"Chemotherapy-induced peripheral neuropathy: current status and progress","volume":"140","author":"Brewer","year":"2016","journal-title":"Gynecol. Oncol."},{"issue":"1","key":"10.1016\/j.jep.2026.121286_bib7","doi-asserted-by":"crossref","DOI":"10.1063\/1.2408420","article-title":"Canonical sampling through velocity rescaling","volume":"126","author":"Bussi","year":"2007","journal-title":"J. Chem. Phys."},{"issue":"11\u201312","key":"10.1016\/j.jep.2026.121286_bib8","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1007\/s00018-016-2194-1","article-title":"Mechanisms of ferroptosis","volume":"73","author":"Cao","year":"2016","journal-title":"Cell. Mol. Life Sci."},{"issue":"2","key":"10.1016\/j.jep.2026.121286_bib9","doi-asserted-by":"crossref","DOI":"10.3390\/jcm12020505","article-title":"A prospective, randomized, placebo-controlled study assessing the efficacy of Chinese herbal medicine (Huangqi Guizhi Wuwu Decoction) in the treatment of albumin-bound paclitaxel-induced peripheral neuropathy","volume":"12","author":"Chai","year":"2023","journal-title":"J. Clin. Med."},{"issue":"1","key":"10.1016\/j.jep.2026.121286_bib10","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-83207-8","article-title":"Total glucosides of paeony ameliorates chemotherapy-induced neuropathic pain by suppressing microglia pyroptosis through the inhibition of KAT2A-mediated p38 pathway activation and succinylation","volume":"14","author":"Chen","year":"2024","journal-title":"Sci. Rep."},{"issue":"9","key":"10.1016\/j.jep.2026.121286_bib11","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1080\/15548627.2020.1810918","article-title":"Ferroptosis: machinery and regulation","volume":"17","author":"Chen","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.jep.2026.121286_bib12","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1231401","article-title":"Oxaliplatin-induced peripheral neurotoxicity in colorectal cancer patients: mechanisms, pharmacokinetics and strategies","volume":"14","author":"Cheng","year":"2023","journal-title":"Front. Pharmacol."},{"issue":"Suppl. 1","key":"10.1016\/j.jep.2026.121286_bib13","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1097\/j.pain.0000000000001540","article-title":"Chemotherapy-induced peripheral neuropathy: where are we now?","volume":"160","author":"Colvin","year":"2019","journal-title":"Pain"},{"key":"10.1016\/j.jep.2026.121286_bib14","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.3389\/fnins.2019.01413","article-title":"Role of spinal cord \u03b1(2)-Adrenoreceptors in noradrenergic inhibition of nociceptive transmission during chemotherapy-induced peripheral neuropathy","volume":"13","author":"Costa-Pereira","year":"2019","journal-title":"Front. Neurosci."},{"issue":"4","key":"10.1016\/j.jep.2026.121286_bib9001","article-title":"Nutritional modulation of immune response in colorectal cancer: a mini review","volume":"5","author":"Evola","year":"2026","journal-title":"Holist Integ Oncol"},{"issue":"23","key":"10.1016\/j.jep.2026.121286_bib15","first-page":"1761","article-title":"Expert consensus on the diagnosis and treatment of chemotherapy-induced peripheral neuropathic pain in Chinese and Western medicine. Chin","author":"Fan","year":"2021","journal-title":"J. Cancer Prev.Treat28"},{"key":"10.1016\/j.jep.2026.121286_bib16","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/978-3-031-92033-2_5","article-title":"Iron and cell death","volume":"1480","author":"Federico","year":"2025","journal-title":"Adv. Exp. Med. Biol."},{"issue":"18","key":"10.1016\/j.jep.2026.121286_bib17","doi-asserted-by":"crossref","DOI":"10.1002\/pmic.201800311","article-title":"GPX4 at the crossroads of lipid homeostasis and ferroptosis","volume":"19","author":"Forcina","year":"2019","journal-title":"Proteomics"},{"key":"10.1016\/j.jep.2026.121286_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102822","article-title":"Butyrate reverses ferroptosis resistance in colorectal cancer by inducing c-Fos-dependent xCT suppression","volume":"65","author":"He","year":"2023","journal-title":"Redox Biol."},{"issue":"1","key":"10.1016\/j.jep.2026.121286_bib19","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1186\/s12935-021-02420-x","article-title":"FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis","volume":"21","author":"Hu","year":"2021","journal-title":"Cancer Cell Int."},{"issue":"1","key":"10.1016\/j.jep.2026.121286_bib20","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.brainresrev.2008.12.011","article-title":"MAP kinase and pain","volume":"60","author":"Ji","year":"2009","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.jep.2026.121286_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2025.110660","article-title":"Epigallocatechin gallate ameliorates oxaliplatin-induced peripheral neuropathy via upregulation of IGF-1 signaling and suppression of neuroinflammation","author":"Kang","year":"2025","journal-title":"Neuropharmacology"},{"issue":"5","key":"10.1016\/j.jep.2026.121286_bib22","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1007\/s10787-025-01729-7","article-title":"Flavonoids regulating NLRP3 inflammasome: a promising approach in alleviating diabetic peripheral neuropathy","volume":"33","author":"Khanna","year":"2025","journal-title":"Inflammopharmacology"},{"issue":"12","key":"10.1016\/j.jep.2026.121286_bib23","doi-asserted-by":"crossref","DOI":"10.3390\/ijms18122626","article-title":"Duloxetine protects against oxaliplatin-induced neuropathic pain and spinal neuron hyperexcitability in rodents","volume":"18","author":"Kim","year":"2017","journal-title":"Int. J. Mol. Sci."},{"issue":"6588","key":"10.1016\/j.jep.2026.121286_bib24","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1126\/science.abf6805","article-title":"A spinal microglia population involved in remitting and relapsing neuropathic pain","volume":"376","author":"Kohno","year":"2022","journal-title":"Science"},{"issue":"1\u20133","key":"10.1016\/j.jep.2026.121286_bib25","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.ejphar.2011.11.037","article-title":"Effects of intrathecal epigallocatechin gallate, an inhibitor of toll-like receptor 4, on chronic neuropathic pain in rats","volume":"676","author":"Kuang","year":"2012","journal-title":"Eur. J. Pharmacol."},{"issue":"9","key":"10.1016\/j.jep.2026.121286_bib26","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1089\/neu.2014.3527","article-title":"Fluoxetine prevents oligodendrocyte cell death by inhibiting microglia activation after spinal cord injury","volume":"32","author":"Lee","year":"2015","journal-title":"J. Neurotrauma"},{"issue":"12","key":"10.1016\/j.jep.2026.121286_bib27","doi-asserted-by":"crossref","first-page":"5013","DOI":"10.18632\/aging.203794","article-title":"Huangqi Guizhi Wuwu Decoction can prevent and treat oxaliplatin-induced neuropathic pain by TNF\u03b1\/IL-1\u03b2\/IL-6\/MAPK\/NF-kB pathway","volume":"14","author":"Li","year":"2022","journal-title":"Aging (Albany NY)"},{"issue":"4","key":"10.1016\/j.jep.2026.121286_bib28","doi-asserted-by":"crossref","first-page":"267","DOI":"10.5607\/en.2018.27.4.267","article-title":"Dexmedetomidine attenuates neuropathic pain by inhibiting P2X7R expression and ERK phosphorylation in rats","volume":"27","author":"Lin","year":"2018","journal-title":"Exp Neurobiol"},{"issue":"8","key":"10.1016\/j.jep.2026.121286_bib29","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1007\/s11655-020-2721-7","article-title":"Combination of quercetin, Hirudin and Cinnamaldehyde Promotes Schwann cell differentiation and myelination against high glucose by inhibiting ERK signaling pathway","volume":"26","author":"Liu","year":"2020","journal-title":"Chin. J. Integr. Med."},{"key":"10.1016\/j.jep.2026.121286_bib30","doi-asserted-by":"crossref","DOI":"10.1038\/sigtrans.2017.23","article-title":"NF-\u03baB signaling in inflammation","volume":"2","author":"Liu","year":"2017","journal-title":"Signal Transduct. Targeted Ther."},{"issue":"6","key":"10.1016\/j.jep.2026.121286_bib31","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1139\/bcb-2021-0513","article-title":"PCDH7 knockdown potentiates colon cancer cells to chemotherapy via inducing ferroptosis and changes in autophagy through restraining MEK1\/2\/ERK\/c-Fos axis","volume":"100","author":"Liu","year":"2022","journal-title":"Biochem. Cell. Biol."},{"issue":"28","key":"10.1016\/j.jep.2026.121286_bib32","doi-asserted-by":"crossref","first-page":"3325","DOI":"10.1200\/JCO.20.01399","article-title":"Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of Adult Cancers: ASCO Guideline update","volume":"38","author":"Loprinzi","year":"2020","journal-title":"J. Clin. Oncol."},{"issue":"Pt 2","key":"10.1016\/j.jep.2026.121286_bib33","article-title":"Injectable GelMA microsphere-integrated hyaluronic acid-polyphenol hydrogel system with multifunctional injury microenvironment modulation promotes peripheral nerve regeneration","volume":"368","author":"Ma","year":"2025","journal-title":"Carbohydr. Polym."},{"issue":"8","key":"10.1016\/j.jep.2026.121286_bib34","doi-asserted-by":"crossref","first-page":"3696","DOI":"10.1021\/acs.jctc.5b00255","article-title":"ff14SB: improving the accuracy of protein side chain and backbone parameters from ff99SB","volume":"11","author":"Maier","year":"2015","journal-title":"J. Chem. Theor. Comput."},{"issue":"10","key":"10.1016\/j.jep.2026.121286_bib35","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0186250","article-title":"Susceptibility of different mouse strains to oxaliplatin peripheral neurotoxicity: phenotypic and genotypic insights","volume":"12","author":"Marmiroli","year":"2017","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.jep.2026.121286_bib36","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s13018-017-0578-z","article-title":"In vivo evaluation of microglia activation by intracranial iron overload in central pain after spinal cord injury","volume":"12","author":"Meng","year":"2017","journal-title":"J. Orthop. Surg. Res."},{"key":"10.1016\/j.jep.2026.121286_bib37","doi-asserted-by":"crossref","first-page":"365","DOI":"10.3389\/fphar.2019.00365","article-title":"Duloxetine, a balanced serotonin-norepinephrine reuptake inhibitor, improves painful chemotherapy-induced peripheral neuropathy by inhibiting activation of p38 MAPK and NF-\u03baB","volume":"10","author":"Meng","year":"2019","journal-title":"Front. Pharmacol."},{"issue":"4","key":"10.1016\/j.jep.2026.121286_bib38","first-page":"128","article-title":"Technical specifications for external pharmacological experiments of traditionalChinese medicines (draft)","volume":"30","author":"Miao","year":"2014","journal-title":"Pharmacol. Clin. Chin. Mater. Med."},{"key":"10.1016\/j.jep.2026.121286_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2022.103847","article-title":"Contribution of ferroptosis and GPX4's dual functions to osteoarthritis progression","volume":"76","author":"Miao","year":"2022","journal-title":"EBioMedicine"},{"key":"10.1016\/j.jep.2026.121286_bib40","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1303937","article-title":"Spinal HMGB1 participates in the early stages of paclitaxel-induced neuropathic pain via microglial TLR4 and RAGE activation","volume":"15","author":"Moraes","year":"2024","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.jep.2026.121286_bib41","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.1021\/ct3010485","article-title":"Improved generalized born solvent model parameters for protein simulations","volume":"9","author":"Nguyen","year":"2013","journal-title":"J. Chem. Theor. Comput."},{"issue":"1","key":"10.1016\/j.jep.2026.121286_bib42","doi-asserted-by":"crossref","DOI":"10.3390\/cimb47010063","article-title":"Metabolite-Sensing receptors: emerging targets for modulating chronic pain pathways","volume":"47","author":"Pu\u015fca\u015fu","year":"2025","journal-title":"Curr. Issues Mol. Biol."},{"issue":"2","key":"10.1016\/j.jep.2026.121286_bib43","doi-asserted-by":"crossref","first-page":"196","DOI":"10.21037\/apm-24-154","article-title":"Chronic chemotherapy-induced peripheral neuropathy: living with neuropathy during and after cancer treatments","volume":"14","author":"Rahman","year":"2025","journal-title":"Ann. Palliat. Med."},{"issue":"4","key":"10.1016\/j.jep.2026.121286_bib44","first-page":"Cd005454","article-title":"Antidepressants for neuropathic pain","volume":"2007","author":"Saarto","year":"2007","journal-title":"Cochrane Database Syst. Rev."},{"issue":"6","key":"10.1016\/j.jep.2026.121286_bib45","doi-asserted-by":"crossref","first-page":"4560","DOI":"10.1007\/s12035-017-0658-4","article-title":"Fos protein as a marker of neuronal activity: a useful tool in the Study of the mechanism of action of natural products with analgesic activity","volume":"55","author":"Santos","year":"2018","journal-title":"Mol. Neurobiol."},{"issue":"Suppl. 2","key":"10.1016\/j.jep.2026.121286_bib46","first-page":"S26","article-title":"Platinum-induced peripheral neurotoxicity: from pathogenesis to treatment","volume":"24","author":"Staff","year":"2019","journal-title":"J. Peripher. Nerv. Syst."},{"key":"10.1016\/j.jep.2026.121286_bib47","article-title":"Dorsal root ganglion-targeted analgesic delivery for effective relief of neuropathic pain","volume":"33","author":"Sun","year":"2025","journal-title":"Mater. Today Bio"},{"issue":"3","key":"10.1016\/j.jep.2026.121286_bib48","first-page":"209","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J. Clin."},{"issue":"10","key":"10.1016\/j.jep.2026.121286_bib49","doi-asserted-by":"crossref","first-page":"6281","DOI":"10.1021\/acs.jctc.1c00645","article-title":"gmx_MMPBSA: a new tool to perform end-state free energy calculations with GROMACS","volume":"17","author":"Vald\u00e9s-Tresanco","year":"2021","journal-title":"J. Chem. Theor. Comput."},{"issue":"10","key":"10.1016\/j.jep.2026.121286_bib50","doi-asserted-by":"crossref","first-page":"6121","DOI":"10.1007\/s12035-023-03463-z","article-title":"Electroacupuncture alleviates neuropathic pain by suppressing ferroptosis in dorsal root ganglion via SAT1\/ALOX15 signaling","volume":"60","author":"Wan","year":"2023","journal-title":"Mol. Neurobiol."},{"issue":"34","key":"10.1016\/j.jep.2026.121286_bib51","doi-asserted-by":"crossref","first-page":"2701","DOI":"10.2174\/0113816128308622240709102830","article-title":"Huangqi Guizhi Wuwu decoction improves inflammatory factor levels in chemotherapy-induced peripheral neuropathy by regulating the arachidonic acid metabolic pathway","volume":"30","author":"Wang","year":"2024","journal-title":"Curr. Pharm. Des."},{"issue":"1","key":"10.1016\/j.jep.2026.121286_bib70","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s44178-022-00007-8","article-title":"CACA guidelines for holistic integrative management of breast cancer","volume":"1","author":"Wu","year":"2022","journal-title":"Holist. Integr. Oncol."},{"key":"10.1016\/j.jep.2026.121286_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.155239","article-title":"Huangqi-Guizhi-Wuwu decoction regulates differentiation of CD4(+) T cell and prevents against experimental autoimmune encephalomyelitis progression in mice","volume":"125","author":"Xu","year":"2024","journal-title":"Phytomedicine"},{"issue":"7","key":"10.1016\/j.jep.2026.121286_bib53","doi-asserted-by":"crossref","DOI":"10.1111\/jcmm.18240","article-title":"Electroacupuncture suppresses neuronal ferroptosis to relieve chronic neuropathic pain","volume":"28","author":"Xue","year":"2024","journal-title":"J. Cell Mol. Med."},{"issue":"1","key":"10.1016\/j.jep.2026.121286_bib54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10571-024-01507-z","article-title":"TMEM16A activation inhibits autophagy in dorsal root ganglion cells, which is associated with the p38 MAPK\/mTOR pathway","volume":"45","author":"Yang","year":"2024","journal-title":"Cell. Mol. Neurobiol."},{"issue":"9","key":"10.1016\/j.jep.2026.121286_bib55","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1038\/s41590-021-00996-0","article-title":"Selenium-GPX4 axis protects follicular helper T cells from ferroptosis","volume":"22","author":"Yao","year":"2021","journal-title":"Nat. Immunol."},{"issue":"1","key":"10.1016\/j.jep.2026.121286_bib56","first-page":"446","article-title":"Efficacy and safety of Huangqi Guizhi wuwu decoction for oxaliplatin-induced peripheral neurotoxicity: a systematic review and meta-analysis","volume":"30","author":"Yu","year":"2024","journal-title":"Alternative Ther. Health Med."},{"issue":"8","key":"10.1016\/j.jep.2026.121286_bib57","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1038\/s41418-022-00939-8","article-title":"EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma","volume":"29","author":"Yuan","year":"2022","journal-title":"Cell Death Differ."},{"issue":"2","key":"10.1016\/j.jep.2026.121286_bib58","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.expneurol.2011.08.016","article-title":"Functional deficits in peripheral nerve mitochondria in rats with paclitaxel- and oxaliplatin-evoked painful peripheral neuropathy","volume":"232","author":"Zheng","year":"2011","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.jep.2026.121286_bib59","doi-asserted-by":"crossref","DOI":"10.1177\/1744806919858260","article-title":"Penehyclidine hydrochloride suppressed peripheral nerve injury-induced neuropathic pain by inhibiting microglial MAPK\/p-p38\/IL-1\u03b2 pathway activation","volume":"15","author":"Zheng","year":"2019","journal-title":"Mol. Pain"},{"issue":"1","key":"10.1016\/j.jep.2026.121286_bib60","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/s12974-019-1476-6","article-title":"Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain","volume":"16","author":"Zhou","year":"2019","journal-title":"J. Neuroinflammation"},{"issue":"2","key":"10.1016\/j.jep.2026.121286_bib61","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0304-3959(83)90201-4","article-title":"Ethical guidelines for investigations of experimental pain in conscious animals","volume":"16","author":"Zimmermann","year":"1983","journal-title":"Pain"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126001376?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126001376?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T16:29:42Z","timestamp":1776184182000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874126001376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":63,"alternative-id":["S0378874126001376"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2026.121286","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A study on the network pharmacology of HQGZWWT that prevents CINP by inhibiting ferroptosis through regulation of the p38\/c-FOS\/NF-kB pathway","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2026.121286","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"121286"}}