{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T10:23:25Z","timestamp":1789986205175,"version":"4.0.1"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82574557"],"award-info":[{"award-number":["82574557"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.jep.2026.121513","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T08:02:40Z","timestamp":1773129760000},"page":"121513","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Broussonetia papyrifera fruit extract attenuates Alzheimer's pathogenesis via disrupting the vicious cycle of A\u03b2 and oxidative stress in C. elegans and cellular models"],"prefix":"10.1016","volume":"364","author":[{"given":"Wen-Bo","family":"Cui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-Yu","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Shuang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-xiang","family":"Lou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Hong","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2026.121513_bib1","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.brainresbull.2021.02.024","article-title":"Effects of vanillic acid on A\u03b21-40-induced oxidative stress and learning and memory deficit in male rats","volume":"170","author":"Ahmadi","year":"2021","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.jep.2026.121513_bib2","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.jalz.2014.04.514","article-title":"At the interface of sensory and motor dysfunctions and Alzheimer's disease","volume":"11","author":"Albers","year":"2015","journal-title":"Alzheimer's Dement."},{"key":"10.1016\/j.jep.2026.121513_bib3","doi-asserted-by":"crossref","DOI":"10.1038\/srep40753","article-title":"Vanillic acid attenuates A\u03b21-42-induced oxidative stress and cognitive impairment in mice","volume":"7","author":"Amin","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2026.121513_bib4","doi-asserted-by":"crossref","first-page":"408","DOI":"10.3390\/antiox11020408","article-title":"Antioxidant therapy in oxidative stress-induced neurodegenerative diseases: role of nanoparticle-based drug delivery systems in clinical translation","volume":"11","author":"Ashok","year":"2022","journal-title":"Antioxidants"},{"key":"10.1016\/j.jep.2026.121513_bib5","doi-asserted-by":"crossref","first-page":"5889","DOI":"10.1038\/s41467-022-33630-0","article-title":"The unfolded protein response reverses the effects of glucose on lifespan in chemically-sterilized C. elegans","volume":"13","author":"Beaudoin-Chabot","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jep.2026.121513_bib6","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.biopha.2015.07.025","article-title":"Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight","volume":"74","author":"Bhat","year":"2015","journal-title":"Biomed. Amp. Pharmacother."},{"key":"10.1016\/j.jep.2026.121513_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jare.2021.09.002","article-title":"Oxyphylla A ameliorates cognitive deficits and alleviates neuropathology via the Akt-GSK3\u03b2 and Nrf2-Keap1-HO-1 pathways in vitro and in vivo murine models of Alzheimer's disease","volume":"34","author":"Bian","year":"2021","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.jep.2026.121513_bib8","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1017\/S0954422419000301","article-title":"The biology of ergothioneine, an antioxidant nutraceutical","volume":"33","author":"Borodina","year":"2020","journal-title":"Nutr. Res. Rev."},{"key":"10.1016\/j.jep.2026.121513_bib9","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1586\/ern.11.57","article-title":"Loss of motor function in preclinical Alzheimer's disease","volume":"11","author":"Buchman","year":"2011","journal-title":"Expert Rev. Neurother."},{"key":"10.1016\/j.jep.2026.121513_bib10","doi-asserted-by":"crossref","first-page":"903","DOI":"10.3390\/ijms19030903","article-title":"Hydroquinone exhibits In Vitro and In Vivo anti-cancer activity in cancer cells and mice","volume":"19","author":"Byeon","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2026.121513_bib11","doi-asserted-by":"crossref","first-page":"819","DOI":"10.3390\/nu14040819","article-title":"Phenolic acids and prevention of cognitive decline: polyphenols with a neuroprotective role in cognitive disorders and alzheimer's disease","volume":"14","author":"Caruso","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.jep.2026.121513_bib12","doi-asserted-by":"crossref","first-page":"18123","DOI":"10.1002\/jcp.28444","article-title":"Antiplatelet, antioxidative, and anti\u2010inflammatory effects of hydroquinone","volume":"234","author":"Chang","year":"2019","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.jep.2026.121513_bib13","doi-asserted-by":"crossref","DOI":"10.1155\/2008\/298010","article-title":"Suppressive effect of hydroquinone, a benzene metabolite, on in vitro inflammatory responses mediated by macrophages, monocytes, and lymphocytes","volume":"2008","author":"Cho","year":"2008","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.jep.2026.121513_bib14","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s12272-001-1161-1","article-title":"Hydroquinone, a major component in cigarette smoke, reduces IFN-\u03b3 production in antigen-primed lymphocytes","volume":"31","author":"Choi","year":"2008","journal-title":"Arch Pharm. Res. (Seoul)"},{"key":"10.1016\/j.jep.2026.121513_bib15","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.brainresbull.2011.11.014","article-title":"Antioxidant properties of natural polyphenols and their therapeutic potentials for Alzheimer's disease","volume":"87","author":"Choi","year":"2012","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.jep.2026.121513_bib16","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/alzrt269","article-title":"Alzheimer's disease drug-development pipeline: few candidates, frequent failures","volume":"6","author":"Cummings","year":"2014","journal-title":"Alzheimers Res. Ther."},{"key":"10.1016\/j.jep.2026.121513_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3233\/JAD-220460","article-title":"Low Xanthophylls, retinol, lycopene, and tocopherols in grey and white matter of brains with alzheimer's disease","volume":"94","author":"Dorey","year":"2023","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.jep.2026.121513_bib18","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.lfs.2018.12.029","article-title":"Crosstalk between mitochondrial dysfunction, oxidative stress, and age related neurodegenerative disease: etiologies and therapeutic strategies","volume":"218","author":"Elfawy","year":"2019","journal-title":"Life Sci."},{"key":"10.1016\/j.jep.2026.121513_bib19","doi-asserted-by":"crossref","DOI":"10.1002\/alz.13417","article-title":"Systematic review and meta\u2010analysis on population attributable fraction for physical inactivity to dementia","author":"Feter","year":"2023","journal-title":"Alzheimer's Dement."},{"key":"10.1016\/j.jep.2026.121513_bib20","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/0926-6917(95)90040-3","article-title":"Inhibition of mitochondrial complexes I and IV by 6-hydroxydopamine","volume":"292","author":"Glinka","year":"1995","journal-title":"Eur. J. Pharmacol. Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.jep.2026.121513_bib21","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1093\/toxsci\/kfw167","article-title":"Hydroquinone strongly alleviates focal ischemic brain injury via blockage of blood\u2013brain barrier disruption in rats","volume":"154","author":"Ha Park","year":"2016","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.jep.2026.121513_bib22","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.bbrc.2012.10.129","article-title":"Soluble oligomers and fibrillar species of amyloid \u03b2-peptide differentially affect cognitive functions and hippocampal inflammatory response","volume":"429","author":"He","year":"2012","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jep.2026.121513_bib24","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.jdermsci.2009.06.003","article-title":"Effects of hydroquinone and its glucoside derivatives on melanogenesis and antioxidation: biosafety as skin whitening agents","volume":"55","author":"Hu","year":"2009","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.jep.2026.121513_bib25","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/nn1372","article-title":"Natural oligomers of the amyloid-\u03b2 protein specifically disrupt cognitive function","volume":"8","author":"James","year":"2005","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.jep.2026.121513_bib26","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1038\/s41591-023-02476-4","article-title":"Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease","volume":"29","author":"Johnson","year":"2023","journal-title":"Nat. Med."},{"key":"10.1016\/j.jep.2026.121513_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.pscia.2023.100021","article-title":"Emerging role of antioxidants in Alzheimer's disease: insight into physiological, pathological mechanisms and management","volume":"2","author":"Kamaljeet","year":"2024","journal-title":"Pharm. Sci. Adv."},{"key":"10.1016\/j.jep.2026.121513_bib28","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1038\/nrd3505","article-title":"The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics","volume":"10","author":"Karran","year":"2011","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.jep.2026.121513_bib29","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2015.00091","article-title":"Researching glutamate-induced cytotoxicity in different cell lines: a comparative\/collective analysis\/study","volume":"9","author":"Kritis","year":"2015","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.jep.2026.121513_bib30","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1007\/s12035-014-8722-9","article-title":"Polyphenols as therapeutic molecules in alzheimer's disease through modulating amyloid pathways","volume":"51","author":"Lakey-Beitia","year":"2015","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.jep.2026.121513_bib31","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/ene.13439","article-title":"Alzheimer's disease","volume":"25","author":"Lane","year":"2018","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.jep.2026.121513_bib32","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1089\/ars.2011.4173","article-title":"Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation","volume":"16","author":"Leuner","year":"2012","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.jep.2026.121513_bib33","first-page":"2325","article-title":"Fructus Broussonetae extract improves cognitive function and endoplasmic reticulum stress in Alzheimer's disease models","volume":"6","author":"Li","year":"2011","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.jep.2026.121513_bib34","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1042\/BCJ20180016","article-title":"Heme degradation enzyme biliverdin IX\u03b2 reductase is required for stem cell glutamine metabolism","volume":"475","author":"Li","year":"2018","journal-title":"Biochem. J."},{"key":"10.1016\/j.jep.2026.121513_bib35","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.4103\/1673-5374.213556","article-title":"Dried Rehmannia root protects against glutamate-induced cytotoxicity to PC12 cells through energy metabolism-related pathways","volume":"12","author":"Liu","year":"2017","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.jep.2026.121513_bib36","doi-asserted-by":"crossref","first-page":"21","DOI":"10.31083\/j.jin.2020.01.1213","article-title":"The Chinese herb Fructus Broussonetiae aids learning and memory in chronic cerebral hypoperfusion by reducing proinflammatory microglia activation in rats","volume":"19","author":"Liu","year":"2020","journal-title":"J. Integr. Neurosci."},{"key":"10.1016\/j.jep.2026.121513_bib37","doi-asserted-by":"crossref","first-page":"e703","DOI":"10.1016\/S2666-7568(23)00212-X","article-title":"Moderate and vigorous leisure time physical activity in older adults and Alzheimer's disease-related mortality in the USA: a dose\u2013response, population-based study","volume":"4","author":"L\u00f3pez-Bueno","year":"2023","journal-title":"Lancet Healthy Longev."},{"key":"10.1016\/j.jep.2026.121513_bib38","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.jff.2017.10.032","article-title":"Peptides from sesame cake reduce oxidative stress and amyloid-\u03b2-induced toxicity by upregulation of SKN-1 in a transgenic Caenorhabditis elegans model of Alzheimer's disease","volume":"39","author":"Ma","year":"2017","journal-title":"J. Funct.Foods"},{"key":"10.1016\/j.jep.2026.121513_bib39","doi-asserted-by":"crossref","first-page":"4365","DOI":"10.1016\/j.cell.2023.08.039","article-title":"Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer's disease pathology","volume":"186","author":"Mathys","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.jep.2026.121513_bib40","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.brainres.2003.12.034","article-title":"The role of oxidative stress, impaired glycolysis and mitochondrial respiratory redox failure in the cytotoxic effects of 6-hydroxydopamine in vitro","volume":"1004","author":"Mazzio","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.jep.2026.121513_bib41","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1021\/np800488p","article-title":"Antioxidant lignans from the fruits of Broussonetia papyrifera","volume":"72","author":"Mei","year":"2009","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.jep.2026.121513_bib42","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1172\/JCI30447","article-title":"Familial Alzheimer disease\u2013linked mutations specifically disrupt Ca2+ leak function of presenilin 1","volume":"117","author":"Nelson","year":"2007","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.jep.2026.121513_bib43","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1111\/j.1468-3083.2006.01670.x","article-title":"The safety of hydroquinone","volume":"20","author":"Nordlund","year":"2006","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"10.1016\/j.jep.2026.121513_bib44","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1093\/gerona\/glad086","article-title":"Vanillic acid improves stress resistance and substantially extends life span in Caenorhabditis elegans","volume":"78","author":"Osorio-Paz","year":"2023","journal-title":"J. Gerontol. Ser. A"},{"key":"10.1016\/j.jep.2026.121513_bib45","doi-asserted-by":"crossref","first-page":"446","DOI":"10.4236\/ajps.2016.73038","article-title":"Chemical composition of the fatty oil from fructus broussonetiae and its effects on rat plasma lipids and adipose tissue","volume":"7","author":"Pang","year":"2016","journal-title":"Am. J. Plant Sci."},{"key":"10.1016\/j.jep.2026.121513_bib46","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.cbi.2017.01.018","article-title":"Neuroprotection and reduced gliosis by pre- and post-treatments of hydroquinone in a gerbil model of transient cerebral ischemia","volume":"278","author":"Park","year":"2017","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.jep.2026.121513_bib47","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.tips.2008.09.001","article-title":"Oxidative stress hypothesis in Alzheimer's disease: a reappraisal","volume":"29","author":"Pratic\u00f2","year":"2008","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.jep.2026.121513_bib48","doi-asserted-by":"crossref","first-page":"S499","DOI":"10.3233\/JAD-2010-100504","article-title":"Amyloid-\u03b2 and mitochondria in aging and alzheimer's disease: implications for synaptic damage and cognitive decline","volume":"20","author":"Reddy","year":"2010","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.jep.2026.121513_bib49","first-page":"14","article-title":"n-Butylidenephthalide protects against dopaminergic neuron degeneration and a-Synuclein accumulation in Caenorhabditis elegans models of parkinson's disease","volume":"9","author":"Ru-Huei","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2026.121513_bib50","first-page":"126","article-title":"C. elegans as a model in developmental neurotoxicology","volume":"36","author":"Ruszkiewicz","year":"2022","journal-title":"FASEB J."},{"key":"10.1016\/j.jep.2026.121513_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2023.113128","article-title":"Omics approaches to investigate the neuroprotective capacity of a citrus sinensis (sweet orange) extract in a Caenorhabditis elegans Alzheimer's model","volume":"172","author":"S\u00e1nchez-Mart\u00ednez","year":"2023","journal-title":"Food Res. Int."},{"key":"10.1016\/j.jep.2026.121513_bib52","doi-asserted-by":"crossref","first-page":"4855","DOI":"10.1021\/jf0735073","article-title":"Challenges for research on polyphenols from foods in alzheimer's disease: bioavailability, metabolism, and cellular and molecular mechanisms","volume":"56","author":"Singh","year":"2008","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jep.2026.121513_bib53","doi-asserted-by":"crossref","first-page":"5906","DOI":"10.3390\/ijms25115906","article-title":"A comprehensive analytical review of polyphenols: evaluating neuroprotection in alzheimer's disease","volume":"25","author":"Vicente-Zurdo","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2026.121513_bib54","doi-asserted-by":"crossref","first-page":"351","DOI":"10.3390\/molecules25020351","article-title":"Effects of Orange extracts on longevity, healthspan, and stress resistance in Caenorhabditis elegans","volume":"25","author":"Wang","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2026.121513_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2020.111808","article-title":"Ferulic acid delayed amyloid \u03b2-induced pathological symptoms by autophagy pathway via a fasting-like effect in Caenorhabditis elegans","volume":"146","author":"Wang","year":"2020","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jep.2026.121513_bib56","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.expneurol.2018.07.018","article-title":"Mutation of hop-1 and pink-1 attenuates vulnerability of neurotoxicity in C. elegans: the role of mitochondria-associated membrane proteins in parkinsonism","volume":"309","author":"Wu","year":"2018","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.jep.2026.121513_bib57","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.1056614","article-title":"Effects of Broussonetia papyrifera (L.) L\u2019H\u00e9r. ex Vent. fruits water extract on hippocampal neurogenesis in the treatment of APP\/PS1 transgenic mice","volume":"13","author":"Yan","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.121513_bib23","article-title":"Antioxidative and anti-inflammatory properties of Chushizi oil from Fructus Broussonetiae","volume":"5","author":"Zhao","year":"2011","journal-title":"J. Med. Plants Res."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126003648?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126003648?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T21:42:07Z","timestamp":1774388527000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874126003648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":57,"alternative-id":["S0378874126003648"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2026.121513","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Broussonetia papyrifera fruit extract attenuates Alzheimer's pathogenesis via disrupting the vicious cycle of A\u03b2 and oxidative stress in C. elegans and cellular models","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2026.121513","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"121513"}}