{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T03:45:04Z","timestamp":1783827904949,"version":"3.55.0"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81874401"],"award-info":[{"award-number":["81874401"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004763","name":"Inner Mongolia Autonomous Region Natural Science Foundation","doi-asserted-by":"publisher","award":["2024SHZR2371"],"award-info":[{"award-number":["2024SHZR2371"]}],"id":[{"id":"10.13039\/501100004763","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.jep.2026.121580","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T16:01:29Z","timestamp":1774368089000},"page":"121580","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Xiaozheng Anshen Formula alleviates podocyte injury in diabetic kidney disease by restoring autophagy flux via inhibiting TRPC6-mediated calcium signaling"],"prefix":"10.1016","volume":"365","author":[{"given":"Ziming","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajia","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingnan","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiran","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruifei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenjie","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1132-0810","authenticated-orcid":false,"given":"Jingwei","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.jep.2026.121580_bib1","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1056\/NEJMoa2410659","article-title":"Finerenone with empagliflozin in chronic kidney disease and type 2 diabetes","volume":"393","author":"Agarwal","year":"2025","journal-title":"N. Engl. J. Med."},{"issue":"5","key":"10.1016\/j.jep.2026.121580_bib2","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.186070","article-title":"Leveraging complementary multi-omics data integration methods for mechanistic insights in kidney diseases","volume":"10","author":"Alakwaa","year":"2025","journal-title":"JCI Insight"},{"issue":"4","key":"10.1016\/j.jep.2026.121580_bib3","doi-asserted-by":"crossref","first-page":"3923","DOI":"10.3390\/ijms24043923","article-title":"New insights into the regulation of mTOR signaling via Ca2+-Binding proteins","volume":"24","author":"Amemiya","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"1 Suppl. 1","key":"10.1016\/j.jep.2026.121580_bib4","first-page":"S239","article-title":"Chronic kidney disease and risk management: standards of care in Diabetes-2025","volume":"48","year":"2025","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jep.2026.121580_bib5","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.53311","article-title":"Structural basis for pharmacological modulation of the TRPC6 channel","volume":"9","author":"Bai","year":"2020","journal-title":"eLife"},{"key":"10.1016\/j.jep.2026.121580_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.112632","article-title":"Prosthechea karwinskii, an orchid used as traditional medicine, exerts anti-inflammatory activity and inhibits ROS","volume":"253","author":"Barrag\u00e1n-Zarate","year":"2020","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.jep.2026.121580_bib7","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.kint.2021.02.024","article-title":"Calpastatin prevents angiotensin II-mediated podocyte injury through maintenance of autophagy","volume":"100","author":"Bensaada","year":"2021","journal-title":"Kidney Int."},{"issue":"12","key":"10.1016\/j.jep.2026.121580_bib8","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.2337\/db23-0032","article-title":"Protease-activated receptor 1-Mediated damage of podocytes in diabetic nephropathy","volume":"72","author":"Bohovyk","year":"2023","journal-title":"Diabetes"},{"issue":"11","key":"10.1016\/j.jep.2026.121580_bib9","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1080\/15548627.2019.1705007","article-title":"Podocytes maintain high basal levels of autophagy independent of mTOR signaling","volume":"16","author":"Bork","year":"2020","journal-title":"Autophagy"},{"key":"10.1016\/j.jep.2026.121580_bib10","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2025.1557813","article-title":"Surrogate endpoints in diabetic kidney disease: current perspectives and future directions","volume":"16","author":"Cao","year":"2025","journal-title":"Front. Endocrinol."},{"issue":"6","key":"10.1016\/j.jep.2026.121580_bib11","doi-asserted-by":"crossref","DOI":"10.1111\/cbdd.14558","article-title":"Network pharmacology and experimental verification to explore the effect of Hedyotis diffusa on alzheimer's disease","volume":"103","author":"Chen","year":"2024","journal-title":"Chem. Biol. Drug Des."},{"key":"10.1016\/j.jep.2026.121580_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2021.153643","article-title":"Atractylodis rhizoma water extract attenuates fructose-induced glomerular injury in rats through anti-oxidation to inhibit TRPC6\/p-CaMK4 signaling","volume":"91","author":"Chen","year":"2021","journal-title":"Phytomedicine"},{"issue":"Pt B","key":"10.1016\/j.jep.2026.121580_bib13","article-title":"Mechanism exploration of QingReXiaoZheng decoction on renoprotection in diabetic kidney disease: integrated network pharmacology, molecular docking and experimental validation","volume":"355","author":"Chen","year":"2026","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121580_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2025.117465","article-title":"Hepatocyte mitochondrial DNA activated store-operated Ca2+ entry via Stim1\/Orai1-induced podocyte injury in trichloroethylene sensitized mice: a new insight in liver and kidney crosstalk","volume":"503","author":"Dong","year":"2025","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"17","key":"10.1016\/j.jep.2026.121580_bib15","doi-asserted-by":"crossref","first-page":"8404","DOI":"10.3390\/ijms26178404","article-title":"Phytochemicals from purwoceng (Pimpinella pruatjan) and their potential in chronic disease prevention: focus on kidney health","volume":"26","author":"Dewi","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2026.121580_bib16","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.cbi.2017.09.010","article-title":"Angiotensin II induces calcium-mediated autophagy in podocytes through enhancing reactive oxygen species levels","volume":"277","author":"Gao","year":"2017","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.jep.2026.121580_bib17","article-title":"Qing-re-xiao-zheng formula modulates gut microbiota and inhibits inflammation in mice with diabetic kidney disease","volume":"8","author":"Gao","year":"2021","journal-title":"Front Med (Lausanne)"},{"issue":"7","key":"10.1016\/j.jep.2026.121580_bib18","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1161\/HYPERTENSIONAHA.125.25045","article-title":"Role of the renin-angiotensin system in blood pressure regulation in smooth muscle-specific Cullin-3 deficient mice","volume":"82","author":"Golosova","year":"2025","journal-title":"Hypertension"},{"issue":"10397","key":"10.1016\/j.jep.2026.121580_bib19","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0140-6736(23)01301-6","article-title":"Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the global burden of disease study 2021","volume":"402","year":"2023","journal-title":"Lancet"},{"issue":"8","key":"10.1016\/j.jep.2026.121580_bib20","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1136\/annrheumdis-2017-212935","article-title":"Metabolic pathways and immunometabolism in rare kidney diseases","volume":"77","author":"Grayson","year":"2018","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jep.2026.121580_bib21","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/6174350","article-title":"Application of herbal medicines with heat-clearing property to anti-microinflammation in the treatment of diabetic kidney disease","volume":"2019","author":"Guo","year":"2019","journal-title":"Evid. Based Complement. Alternat. Med."},{"issue":"1","key":"10.1016\/j.jep.2026.121580_bib22","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-09952-6","article-title":"Impact of optimal anti-proteinuric therapy on the prevention of diabetic kidney disease progression","volume":"15","author":"Ismail","year":"2025","journal-title":"Sci. Rep."},{"issue":"8","key":"10.1016\/j.jep.2026.121580_bib23","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1161\/CIRCULATIONAHA.123.065251","article-title":"Cardiorenal biomarkers, canagliflozin, and outcomes in diabetic kidney disease: the CREDENCE trial","volume":"148","author":"Januzzi","year":"2023","journal-title":"Circulation"},{"issue":"20","key":"10.1016\/j.jep.2026.121580_bib24","doi-asserted-by":"crossref","first-page":"5004","DOI":"10.1111\/bph.17431","article-title":"TRPC6 suppresses liver fibrosis by inhibiting hepatic stellate cell activation via CaMK4-CREB pathway","volume":"182","author":"Jiang","year":"2025","journal-title":"Br. J. Pharmacol."},{"issue":"2","key":"10.1016\/j.jep.2026.121580_bib25","doi-asserted-by":"crossref","first-page":"2559","DOI":"10.3390\/ijms16022559","article-title":"Sinomenine hydrochloride protects against polymicrobial sepsis via autophagy","volume":"16","author":"Jiang","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2026.121580_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115246","article-title":"Jiedu tongluo baoshen formula enhances podocyte autophagy and reduces proteinuria in diabetic kidney disease by inhibiting PI3K\/Akt\/mTOR signaling pathway","volume":"293","author":"Jin","year":"2022","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.jep.2026.121580_bib27","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/s41572-020-0196-7","article-title":"Podocytopathies","volume":"6","author":"Kopp","year":"2020","journal-title":"Nat. Rev. Dis. Primers"},{"issue":"1","key":"10.1016\/j.jep.2026.121580_bib28","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.tcb.2024.08.007","article-title":"Crosstalk between mitochondria-ER contact sites and the apoptotic machinery as a novel health meter","volume":"35","author":"Larra\u00f1aga-SanMiguel","year":"2025","journal-title":"Trends Cell Biol."},{"issue":"1","key":"10.1016\/j.jep.2026.121580_bib29","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/s13020-024-00923-z","article-title":"\"Qi Nan\" agarwood restores podocyte autophagy in diabetic kidney disease by targeting EGFR signaling pathway","volume":"19","author":"Li","year":"2024","journal-title":"Chin. Med."},{"issue":"7","key":"10.1016\/j.jep.2026.121580_bib30","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1681\/ASN.0000000634","article-title":"PIEZO1-Mediated calcium signaling and podocyte injury in diabetic kidney disease","volume":"36","author":"Li","year":"2025","journal-title":"J. Am. Soc. Nephrol."},{"issue":"Suppl. 2","key":"10.1016\/j.jep.2026.121580_bib31","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/nep.70030","article-title":"Asian Pacific society of nephrology clinical practice guideline on diabetic kidney Disease-2025 update","volume":"30","author":"Liew","year":"2025","journal-title":"Nephrology (Carlton)"},{"key":"10.1016\/j.jep.2026.121580_bib32","article-title":"Biomarker identification and pathway analysis of Astragalus membranaceus and Curcuma zedoaria couplet medicines on adenine-induced chronic kidney disease in rats based on metabolomics","volume":"14","author":"Lu","year":"2023","journal-title":"Front. Pharmacol."},{"issue":"2","key":"10.1016\/j.jep.2026.121580_bib33","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.kint.2024.10.026","article-title":"TRAIL induces podocyte PANoptosis via death receptor 5 in diabetic kidney disease","volume":"107","author":"Lv","year":"2025","journal-title":"Kidney Int."},{"key":"10.1016\/j.jep.2026.121580_bib34","article-title":"Mechanisms of diabetic kidney disease and established and emerging treatments","author":"Martinez Leon","year":"2025","journal-title":"Nat. Rev. Endocrinol."},{"issue":"6","key":"10.1016\/j.jep.2026.121580_bib35","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/j.kint.2016.01.012","article-title":"Podocyte injury and its consequences","volume":"89","author":"Nagata","year":"2016","journal-title":"Kidney Int."},{"issue":"4","key":"10.1016\/j.jep.2026.121580_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.dsx.2025.103237","article-title":"Composite renal outcome in prospectively performed biopsy proven diabetic kidney disease versus non-diabetic kidney disease: a longitudinal follow up","volume":"19","author":"Neogi","year":"2025","journal-title":"Diabetes Metabol. Syndr."},{"key":"10.1016\/j.jep.2026.121580_bib37","article-title":"A review of the protective effects of natural compounds against podocyte injury in diabetic kidney disease","volume":"130","author":"Niu","year":"2025","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2026.121580_bib38","article-title":"Targeting TRPC6 in podocytopathies: why clinical translation remains a challenge?","author":"Patel","year":"2025","journal-title":"Pharmacol. Rep."},{"issue":"4","key":"10.1016\/j.jep.2026.121580_bib39","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1053\/j.ajkd.2009.07.003","article-title":"Epithelial-mesenchymal transition and podocyte loss in diabetic kidney disease","volume":"54","author":"Reidy","year":"2009","journal-title":"Am. J. Kidney Dis."},{"issue":"4","key":"10.1016\/j.jep.2026.121580_bib40","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.phrs.2005.05.004","article-title":"Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening","volume":"52","author":"Srinivasan","year":"2005","journal-title":"Pharmacol. Res."},{"issue":"11","key":"10.1016\/j.jep.2026.121580_bib41","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1681\/ASN.0000000000000212","article-title":"Podocyte injury in diabetic kidney disease in mouse models involves TRPC6-mediated calpain activation impairing autophagy","volume":"34","author":"Salemkour","year":"2023","journal-title":"J. Am. Soc. Nephrol."},{"issue":"4","key":"10.1016\/j.jep.2026.121580_bib42","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1007\/s10753-023-01808-3","article-title":"Transient receptor potential canonical 6 (TRPC6) channel in the pathogenesis of diseases: a jack of many trades","volume":"46","author":"Saqib","year":"2023","journal-title":"Inflammation"},{"issue":"1","key":"10.1016\/j.jep.2026.121580_bib43","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1152\/physrev.00013.2022","article-title":"Ion channels and channelopathies in glomeruli","volume":"103","author":"Staruschenko","year":"2023","journal-title":"Physiol. Rev."},{"issue":"3","key":"10.1016\/j.jep.2026.121580_bib44","first-page":"310","article-title":"Yiqi qingre xiaozheng formula protects against diabetic nephropathy by restoring autophagy in mice","volume":"10","author":"Sun","year":"2023","journal-title":"J. Tradit. Chin. Med. Sci."},{"issue":"9","key":"10.1016\/j.jep.2026.121580_bib45","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1016\/j.apsb.2020.12.020","article-title":"Clinical efficacies, underlying mechanisms and molecular targets of Chinese medicines for diabetic nephropathy treatment and management","volume":"11","author":"Tang","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"issue":"4","key":"10.1016\/j.jep.2026.121580_bib46","first-page":"873","article-title":"Traditional Chinese herbal medicine qingre xiaozheng formula improves renal outcomes in patients with diabetic kidney disease: a retrospective study","volume":"45","author":"Weiwei","year":"2025","journal-title":"J. Tradit. Chin. Med."},{"issue":"1","key":"10.1016\/j.jep.2026.121580_bib47","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1186\/s12933-025-02850-1","article-title":"Microvascular dysfunction across organs in heart failure with preserved ejection fraction: the PROSE-HFpEF case-control study","volume":"24","author":"Weerts","year":"2025","journal-title":"Cardiovasc. Diabetol."},{"issue":"2","key":"10.1016\/j.jep.2026.121580_bib48","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1681\/ASN.0000000501","article-title":"Natural history and clinicopathological associations of TRPC6-Associated podocytopathy","volume":"36","author":"Wooden","year":"2025","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.jep.2026.121580_bib49","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.992597","article-title":"Qing-re-xiao-zheng-Yi-Qi formula relieves kidney damage and activates mitophagy in diabetic kidney disease","volume":"13","author":"Wu","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.jep.2026.121580_bib50","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1186\/s12951-025-03487-8","article-title":"TRPC6-targeted dexamethasone nanobubbles with ultrasound-guided theranostics for adriamycin-induced nephropathy","volume":"23","author":"Wu","year":"2025","journal-title":"J. Nanobiotechnol."},{"issue":"13","key":"10.1016\/j.jep.2026.121580_bib51","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1001\/jama.2023.17002","article-title":"Estimated glomerular filtration rate, albuminuria, and adverse outcomes: an individual-participant data meta-analysis","volume":"330","author":"Grams","year":"2023","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.jep.2026.121580_bib52","doi-asserted-by":"crossref","first-page":"61","DOI":"10.4161\/auto.6.1.10326","article-title":"Control of basal autophagy by calpain1 mediated cleavage of ATG5","volume":"6","author":"Xia","year":"2010","journal-title":"Autophagy"},{"key":"10.1016\/j.jep.2026.121580_bib53","doi-asserted-by":"crossref","first-page":"361","DOI":"10.2147\/DDDT.S234262","article-title":"Tetrandrine suppresses transient receptor potential cation channel protein 6 overexpression-induced podocyte damage via blockage of RhoA\/ROCK1 signaling","volume":"14","author":"Yu","year":"2020","journal-title":"Drug Des. Dev. Ther."},{"issue":"10","key":"10.1016\/j.jep.2026.121580_bib54","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1136\/ard-2023-224242","article-title":"SGLT2 inhibitors alleviated podocyte damage in lupus nephritis by decreasing inflammation and enhancing autophagy","volume":"82","author":"Zhao","year":"2023","journal-title":"Ann. Rheum. Dis."},{"issue":"15","key":"10.1016\/j.jep.2026.121580_bib55","doi-asserted-by":"crossref","first-page":"8635","DOI":"10.3390\/ijms23158635","article-title":"Identification of novel inhibitors targeting SGK1 via ensemble-based virtual screening method, biological evaluation and molecular dynamics simulation","volume":"23","author":"Zhang","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2026.121580_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.120157","article-title":"Qing-Re-Xiao-Zheng-(Yi-Qi) formula attenuates the renal podocyte ferroptosis in diabetic kidney disease through AMPK pathway","volume":"351","author":"Zhang","year":"2025","journal-title":"J. Ethnopharmacol."},{"issue":"3","key":"10.1016\/j.jep.2026.121580_bib57","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1172\/JCI76344","article-title":"Cytosolic HMGB1 controls the cellular autophagy\/apoptosis checkpoint during inflammation","volume":"125","author":"Zhu","year":"2015","journal-title":"J. Clin. Investig."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126004319?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126004319?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T12:09:22Z","timestamp":1776168562000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874126004319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":57,"alternative-id":["S0378874126004319"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2026.121580","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Xiaozheng Anshen Formula alleviates podocyte injury in diabetic kidney disease by restoring autophagy flux via inhibiting TRPC6-mediated calcium signaling","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2026.121580","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"121580"}}