{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T04:30:39Z","timestamp":1788237039356,"version":"build-2803163510"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010883","name":"Traditional Chinese Medicine Bureau of Guangdong Province","doi-asserted-by":"publisher","award":["20251426"],"award-info":[{"award-number":["20251426"]}],"id":[{"id":"10.13039\/501100010883","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82405252"],"award-info":[{"award-number":["82405252"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82305181"],"award-info":[{"award-number":["82305181"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82474601"],"award-info":[{"award-number":["82474601"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017607","name":"Shenzhen Municipal Fundamental Research Program","doi-asserted-by":"publisher","award":["JCYJ20220531092209021"],"award-info":[{"award-number":["JCYJ20220531092209021"]}],"id":[{"id":"10.13039\/501100017607","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017607","name":"Shenzhen Municipal Fundamental Research Program","doi-asserted-by":"publisher","award":["JCYJ20250604150049018"],"award-info":[{"award-number":["JCYJ20250604150049018"]}],"id":[{"id":"10.13039\/501100017607","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.jep.2026.121585","type":"journal-article","created":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T07:28:54Z","timestamp":1774682934000},"page":"121585","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Xiaoyaosan ameliorates stress-induced MASH via modulating IL-1R1\/RXR\u03b1-mediated liver-brain crosstalk"],"prefix":"10.1016","volume":"365","author":[{"given":"Yi","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoru","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuya","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiheng","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianyin","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjuan","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shibing","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Buping","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danping","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiqu","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiqing","family":"Ao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangdong","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mianmian","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2026.121585_bib1","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.pharmthera.2019.01.006","article-title":"Vitamin A signaling and homeostasis in obesity, diabetes, and metabolic disorders","volume":"197","author":"Blaner","year":"2019","journal-title":"Pharmacol. Ther."},{"issue":"7","key":"10.1016\/j.jep.2026.121585_bib2","doi-asserted-by":"crossref","first-page":"3611","DOI":"10.1016\/j.apsb.2025.05.023","article-title":"RXR\u03b1 modulates hepatic stellate cell activation and liver fibrosis by targeting CaMKK\u03b2-AMPK\u03b1 axis","volume":"15","author":"Cai","year":"2025","journal-title":"Acta Pharm. Sin. B"},{"issue":"2","key":"10.1016\/j.jep.2026.121585_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmet.2025.11.010","article-title":"Bile acids regulate lipid metabolism through selective actions on fatty acid absorption","volume":"38","author":"Chan","year":"2026","journal-title":"Cell Metab."},{"key":"10.1016\/j.jep.2026.121585_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.157078","article-title":"Xiaoyaosan improves depression-like behaviours in mice with post-stroke depression by modulating gut microbiota and microbial metabolism and regulating P2X7R\/NLRP3 inflammasome","volume":"145","author":"Chen","year":"2025","journal-title":"Phytomedicine"},{"issue":"3","key":"10.1016\/j.jep.2026.121585_bib5","doi-asserted-by":"crossref","DOI":"10.3390\/nu15030795","article-title":"The role of the stress response in metabolic dysfunction-associated fatty liver disease: a Psychoneuroendocrineimmunology-Based perspective","volume":"15","author":"Demori","year":"2023","journal-title":"Nutrients"},{"issue":"3","key":"10.1016\/j.jep.2026.121585_bib6","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/s41573-024-01084-2","article-title":"Therapeutic landscape of metabolic dysfunction-associated steatohepatitis (MASH)","volume":"24","author":"Do","year":"2025","journal-title":"Nat. Rev. Drug Discov."},{"issue":"11","key":"10.1016\/j.jep.2026.121585_bib7","doi-asserted-by":"crossref","first-page":"3120","DOI":"10.1002\/hep4.2066","article-title":"Population-based meta-analysis and gene-set enrichment identifies FXR\/RXR pathway as common to fatty liver disease and serum lipids","volume":"6","author":"Handelman","year":"2022","journal-title":"Hepatol. Commun."},{"issue":"30","key":"10.1016\/j.jep.2026.121585_bib8","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.ado3141","article-title":"Atf3-mediated metabolic reprogramming in hepatic macrophage orchestrates metabolic dysfunction-associated steatohepatitis","volume":"10","author":"Hu","year":"2024","journal-title":"Sci. Adv."},{"key":"10.1016\/j.jep.2026.121585_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114612","article-title":"Xiaoyao San attenuates hepatic steatosis through estrogen receptor \u03b1 pathway in ovariectomized ApoE-\/- mice","volume":"282","author":"Hu","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121585_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2025.137577","article-title":"Effects of co-exposure to heat and ozone on lipid metabolism in the liver and adipose tissue of C57BL\/6J male mice","volume":"489","author":"Jiang","year":"2025","journal-title":"J. Hazard. Mater."},{"issue":"3","key":"10.1016\/j.jep.2026.121585_bib11","first-page":"446","article-title":"Diagnosis and treatment guideline for Chinese medicine on non-alcoholic steatohepatitis","volume":"41","author":"Jiao","year":"2025","journal-title":"J. Clin. Hepatol."},{"issue":"8","key":"10.1016\/j.jep.2026.121585_bib12","doi-asserted-by":"crossref","DOI":"10.1097\/HC9.0000000000000741","article-title":"Tides of emotion: hepatologists' role in navigating depression and anxiety in liver disease","volume":"9","author":"Khan","year":"2025","journal-title":"Hepatol. Commun."},{"key":"10.1016\/j.jep.2026.121585_bib13","article-title":"Liver stiffness directs intrahepatic cholesterol accumulation through YAP\/TAZ in metabolic dysfunction-associated steatotic liver disease","author":"Lee","year":"2026","journal-title":"Adv. Sci. (Weinh.)"},{"key":"10.1016\/j.jep.2026.121585_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.114999","article-title":"Xiaoyao powder in the treatment of non-alcoholic fatty liver disease: a systematic review and meta-analysis","volume":"288","author":"Liu","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121585_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.157221","article-title":"Xiaoyao San's dual efficacy in NAFLD and depression: unraveling the mechanisms via network pharmacology and multi-omics","volume":"147","author":"Liu","year":"2025","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2026.121585_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.metabol.2026.156511","article-title":"Natural polyketide enterocin inhibits ASGR1 to enhance cholesterol efflux and regulate hepatic lipid metabolism","volume":"177","author":"Liu","year":"2026","journal-title":"Metabolism"},{"key":"10.1016\/j.jep.2026.121585_bib17","first-page":"1100","article-title":"Paeoniflorin ameliorates metabolic dysfunction-associated steatotic liver disease by SYK\/SH3BP2 signaling pathway","volume":"9","author":"Liu","year":"2026","journal-title":"Research (Wash D C)"},{"key":"10.1016\/j.jep.2026.121585_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.167395","article-title":"Exposure to low-intensity noise exacerbates nonalcoholic fatty liver disease by activating hypothalamus pituitary adrenal axis","volume":"906","author":"Luo","year":"2024","journal-title":"Sci. Total Environ."},{"issue":"3","key":"10.1016\/j.jep.2026.121585_bib19","first-page":"732","article-title":"ZHOU xiao-zhou's experience in treating non-alcoholic fatty liver disease based on the therapeutic principle of treating liver and spleen simultaneously","volume":"40","author":"Ma","year":"2023","journal-title":"J. Guangzhou Univ. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2026.121585_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2023.176137","article-title":"Promoting reverse cholesterol transport contributes to the amelioration of atherosclerosis by paeoniflorin","volume":"961","author":"Man Wu","year":"2023","journal-title":"Eur. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.jep.2026.121585_bib21","first-page":"339","article-title":"Expert consensus on integrated traditional Chinese and WesternMedicine diagnosis and treatment of non-alcoholic fatty liver disease (2025)","volume":"33","year":"2025","journal-title":"Chin. J. Integr. Tradit. West. Med. Digest."},{"issue":"7","key":"10.1016\/j.jep.2026.121585_bib22","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.4254\/wjh.v16.i7.1051","article-title":"Hepatoprotective effects of Xiaoyao San formula on hepatic steatosis and inflammation via regulating the sex hormones metabolism","volume":"16","author":"Mei","year":"2024","journal-title":"World J. Hepatol."},{"key":"10.1016\/j.jep.2026.121585_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.plipres.2026.101380","article-title":"Nutrigenomics of fat-soluble vitamins and micronutrients in hepatocyte lipotoxicity and MASLD","author":"Migni","year":"2026","journal-title":"Prog. Lipid Res."},{"issue":"18","key":"10.1016\/j.jep.2026.121585_bib24","doi-asserted-by":"crossref","first-page":"16338","DOI":"10.1021\/acs.jmedchem.4c01231","article-title":"Tuning RXR modulators for PGC1\u03b1 recruitment","volume":"67","author":"Nawa","year":"2024","journal-title":"J. Med. Chem."},{"issue":"21","key":"10.1016\/j.jep.2026.121585_bib25","doi-asserted-by":"crossref","DOI":"10.3390\/foods14213746","article-title":"Glycyrrhiza glabra L. extracts prevent LPS-induced inflammation in RAW264.7 cells by targeting pro-inflammatory cytokines, mediators and the JAK\/STAT signaling pathway","volume":"14","author":"Perri","year":"2025","journal-title":"Foods"},{"issue":"5","key":"10.1016\/j.jep.2026.121585_bib26","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/s41575-023-00888-8","article-title":"Hepatic glucose metabolism in the steatotic liver","volume":"21","author":"Scoditti","year":"2024","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"11","key":"10.1016\/j.jep.2026.121585_bib27","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1016\/j.immuni.2025.10.012","article-title":"A myeloid Tet2-IL-1\u03b2 axis modulates intestinal inflammation by restricting catecholaminergic stimulation of enterochromaffin cell differentiation","volume":"58","author":"Sharma","year":"2025","journal-title":"Immunity"},{"issue":"3","key":"10.1016\/j.jep.2026.121585_bib28","doi-asserted-by":"crossref","first-page":"116","DOI":"10.5483\/BMBRep.2024-0058","article-title":"Neutrophils in MASLD and MASH","volume":"58","author":"Shrestha","year":"2025","journal-title":"BMB Rep."},{"key":"10.1016\/j.jep.2026.121585_bib29","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.bbi.2016.08.021","article-title":"Chronic psychological stress and high-fat high-fructose diet disrupt metabolic and inflammatory gene networks in the brain, liver, and gut and promote behavioral deficits in mice","volume":"59","author":"Sousa Rodrigues","year":"2017","journal-title":"Brain Behav. Immun."},{"issue":"18","key":"10.1016\/j.jep.2026.121585_bib30","doi-asserted-by":"crossref","DOI":"10.1172\/JCI186420","article-title":"MASH: the nexus of metabolism, inflammation, and fibrosis","volume":"135","author":"Steinberg","year":"2025","journal-title":"J. Clin. Investig."},{"issue":"2","key":"10.1016\/j.jep.2026.121585_bib31","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.jhep.2025.02.033","article-title":"Integrative metabolism in MASLD and MASH: pathophysiology and emerging mechanisms","volume":"83","author":"Steinberg","year":"2025","journal-title":"J. Hepatol."},{"issue":"D1","key":"10.1016\/j.jep.2026.121585_bib32","doi-asserted-by":"crossref","first-page":"D638","DOI":"10.1093\/nar\/gkac1000","article-title":"The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest","volume":"51","author":"Szklarczyk","year":"2023","journal-title":"Nucleic Acids Res."},{"issue":"6","key":"10.1016\/j.jep.2026.121585_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2021.101331","article-title":"A retinoic acid receptor \u03b22 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease","volume":"297","author":"Tang","year":"2021","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.jep.2026.121585_bib34","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/j.jhep.2024.06.016","article-title":"Inflammasomes in chronic liver disease: hepatic injury, fibrosis progression and systemic inflammation","volume":"81","author":"Taru","year":"2024","journal-title":"J. Hepatol."},{"issue":"1","key":"10.1016\/j.jep.2026.121585_bib35","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/s12072-025-10943-y","article-title":"Depression and MASLD: a shared burden of mind and metabolism","volume":"20","author":"Varshney","year":"2026","journal-title":"Hepatol. Int."},{"issue":"29","key":"10.1016\/j.jep.2026.121585_bib36","doi-asserted-by":"crossref","first-page":"10608","DOI":"10.1080\/10408398.2023.2227258","article-title":"Increasing adipocyte number and reducing adipocyte size: the role of retinoids in adipose tissue development and metabolism","volume":"64","author":"Wang","year":"2024","journal-title":"Crit. Rev. Food Sci. Nutr."},{"issue":"6","key":"10.1016\/j.jep.2026.121585_bib37","doi-asserted-by":"crossref","DOI":"10.1002\/cai2.148","article-title":"Retinoic acid receptor responder 2 and lipid metabolic reprogramming: a new insight into brain metastasis","volume":"3","author":"Wang","year":"2024","journal-title":"Cancer Innov."},{"key":"10.1016\/j.jep.2026.121585_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.nut.2024.112604","article-title":"Dietary quality, perceived health, and psychological status as key risk factors for newly developed metabolic dysfunction-associated steatotic liver disease in a longitudinal study","volume":"130","author":"Wu","year":"2025","journal-title":"Nutrition"},{"key":"10.1016\/j.jep.2026.121585_bib39","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.933674","article-title":"Chronic unpredictable mild stress-induced mouse ovarian insufficiency by interrupting lipid homeostasis in the ovary","volume":"10","author":"Xiang","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"issue":"6","key":"10.1016\/j.jep.2026.121585_bib40","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/j.cmet.2024.04.020","article-title":"Myocardial infarction accelerates the progression of MASH by triggering immunoinflammatory response and induction of periosti","volume":"36","author":"Xie","year":"2024","journal-title":"Cell Metab."},{"key":"10.1016\/j.jep.2026.121585_bib41","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1464655","article-title":"Retinoid X receptor heterodimers in hepatic function: structural insights and therapeutic potential","volume":"15","author":"Xu","year":"2024","journal-title":"Front. Pharmacol."},{"issue":"12","key":"10.1016\/j.jep.2026.121585_bib42","first-page":"1961","article-title":"Restraint stress promotes nonalcoholic steatohepatitis by regulating the farnesoid X receptor\/NLRP3 signaling pathway","volume":"55","author":"Yang","year":"2023","journal-title":"Acta Biochim. Biophys. Sin."},{"key":"10.1016\/j.jep.2026.121585_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.154703","article-title":"Targeting mTOR\/YY1 signaling pathway by quercetin through CYP7A1-mediated cholesterol-to-bile acids conversion alleviated type 2 diabetes mellitus induced hepatic lipid accumulation","volume":"113","author":"Yang","year":"2023","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2026.121585_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116360","article-title":"SNS alleviates depression-like behaviors in CUMS mice by regluating dendritic spines via NCOA4-mediated ferritinophagy","volume":"312","author":"Zhang","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121585_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.120184","article-title":"Xiaoyaosan alleviates chronic psychological stress-induced TH17\/Treg imbalance via modulation of the FKBP5\/NF-\u03baB axis","volume":"352","author":"Zhang","year":"2025","journal-title":"J. Ethnopharmacol."},{"issue":"12","key":"10.1016\/j.jep.2026.121585_bib46","doi-asserted-by":"crossref","DOI":"10.3390\/nu14122411","article-title":"Alisol B alleviates hepatocyte lipid accumulation and lipotoxicity via regulating RAR\u03b1-PPAR\u03b3-CD36 Cascade and attenuates non-alcoholic steatohepatitis in mice","volume":"14","author":"Zhao","year":"2022","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jep.2026.121585_bib47","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1038\/s41467-019-09234-6","article-title":"Metascape provides a biologist-oriented resource for the analysis of systems-level datasets","volume":"10","author":"Zhou","year":"2019","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.jep.2026.121585_bib48","article-title":"Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation","volume":"5","author":"Zhu","year":"2024","journal-title":"Cell Rep. Med."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126004368?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126004368?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T17:20:44Z","timestamp":1776187244000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874126004368"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":48,"alternative-id":["S0378874126004368"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2026.121585","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Xiaoyaosan ameliorates stress-induced MASH via modulating IL-1R1\/RXR\u03b1-mediated liver-brain crosstalk","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2026.121585","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"121585"}}