{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T20:56:26Z","timestamp":1792443386226,"version":"4.5.0"},"reference-count":188,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81602559"],"award-info":[{"award-number":["81602559"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.jep.2026.121703","type":"journal-article","created":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T23:51:59Z","timestamp":1776383519000},"page":"121703","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Advanced extraction to targeted delivery: A holistic review of technological innovations and therapeutic mechanisms of Ginkgo biloba extract"],"prefix":"10.1016","volume":"367","author":[{"given":"Meng","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hechao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6284-8993","authenticated-orcid":false,"given":"Yanhua","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.jep.2026.121703_bib1","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.phrs.2007.09.011","article-title":"Stabilization of mitochondrial function by ginkgo biloba extract (EGb 761)","volume":"56","author":"Abdel-Kader","year":"2007","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.jep.2026.121703_bib2","first-page":"1","article-title":"Improved antidiabetic potential of quercetin-loaded chitosan-lecithin nanoparticles for effective glycaemic control","author":"Ahmad","year":"2025","journal-title":"J. Drug Target."},{"key":"10.1016\/j.jep.2026.121703_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.prmcm.2023.100331","article-title":"Ginkgo biloba: an updated review on pharmacological, ethnobotanical, and phytochemical studies","volume":"9","author":"Akaberi","year":"2023","journal-title":"Pharmacological Research - Modern Chinese Medicine"},{"key":"10.1016\/j.jep.2026.121703_bib4","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3389\/fnins.2025.1634601","article-title":"Potential therapeutic effects of ebixa , ginkgo biloba , and selenium in a cadmium chloride-induced Alzheimer'S disease manifestations in rats","volume":"19","author":"Alrikabi","year":"2025","journal-title":"Front. Neurosci."},{"issue":"2","key":"10.1016\/j.jep.2026.121703_bib5","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/1541-4337.12253","article-title":"Green extraction methods for polyphenols from plant matrices and their byproducts: a review","volume":"16","author":"Ameer","year":"2017","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"issue":"9","key":"10.1016\/j.jep.2026.121703_bib6","doi-asserted-by":"crossref","first-page":"6961","DOI":"10.1007\/s11033-020-05755-2","article-title":"Ginkgo biloba attenuated hepatotoxicity induced by combined exposure to cadmium and fluoride via modulating the redox imbalance, bax\/bcl-2 and NF-kb signaling pathways in male rats","volume":"47","author":"Arab-Nozari","year":"2020","journal-title":"Mol. Biol. Rep."},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib7","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1080\/19390211.2025.2507612","article-title":"Effects of nano-quercetin on cypermethrin induced liver injury in rabbits","volume":"22","author":"Ashraf","year":"2025","journal-title":"J. Diet. Suppl."},{"issue":"3","key":"10.1016\/j.jep.2026.121703_bib8","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1007\/s10787-023-01164-6","article-title":"Protective effects of curcumin and ginkgo biloba extract combination on a new model of Alzheimer'S disease","volume":"31","author":"Assi","year":"2023","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.jep.2026.121703_bib9","doi-asserted-by":"crossref","first-page":"735","DOI":"10.2147\/DDDT.S157113","article-title":"The efficacy and safety of ginkgo biloba extract as an adjuvant in type 2 diabetes mellitus patients ineffectively managed with metformin : a double-blind , randomized , placebo-controlled trial","volume":"12","author":"Aziz","year":"2018","journal-title":"Drug Des. Dev. Ther."},{"issue":"10","key":"10.1016\/j.jep.2026.121703_bib10","doi-asserted-by":"crossref","first-page":"13745","DOI":"10.1007\/s00210-025-03987-2","article-title":"Quercetin loaded-magnetic zeolite nano-composite material and evaluate its anti-cancer effect","volume":"398","author":"Babaei","year":"2025","journal-title":"Naunyn-Schmiedebergs Arch Pharmacol"},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib11","doi-asserted-by":"crossref","first-page":"373","DOI":"10.3736\/jcim20100413","article-title":"[Effects of ginkgo biloba extract 50 preconditioning on contents of inflammation-related cytokines in myocardium of rats with ischemia-reperfusion injury","volume":"8","author":"Bao","year":"2010","journal-title":"Zhong Xi Yi Jie He Xue Bao"},{"issue":"10","key":"10.1016\/j.jep.2026.121703_bib12","doi-asserted-by":"crossref","DOI":"10.3390\/molecules28103993","article-title":"The potential of ginkgo biloba as a source of biologically active compounds-a review of the recent literature and patents","volume":"28","author":"Biernacka","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2026.121703_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2024.141018","article-title":"The potential of dried ginkgo biloba leaves as a novel ingredient in fermented beverages of enhanced flavour and antioxidant properties","volume":"461","author":"Biernacka","year":"2024","journal-title":"Food Chem."},{"issue":"9","key":"10.1016\/j.jep.2026.121703_bib14","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/s41580-019-0129-z","article-title":"PI3k isoforms in cell signalling and vesicle trafficking","volume":"20","author":"Bilanges","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jep.2026.121703_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2024.139979","article-title":"Combinative effect of pulsed-light irradiation and solid-state fermentation on ginkgolic acids, ginkgols, ginkgolides, bilobalide, flavonoids, product quality and sensory assessment of ginkgo biloba dark tea","volume":"456","author":"Boateng","year":"2024","journal-title":"Food Chem."},{"key":"10.1016\/j.jep.2026.121703_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2024.139284","article-title":"Separation and purification of polyprenols from ginkgo biloba leaves by silver ion anchored on imidazole-based ionic liquid functionalized mesoporous MCM-41 sorbent","volume":"450","author":"Boateng","year":"2024","journal-title":"Food Chem."},{"issue":"1","key":"10.1016\/j.jep.2026.121703_bib17","doi-asserted-by":"crossref","DOI":"10.3390\/brainsci15010012","article-title":"Ginkgo biloba extract prescriptions are associated with slower progression of dementia severity-analysis of longitudinal real-world data","volume":"15","author":"Bohlken","year":"2024","journal-title":"Brain Sci."},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib18","first-page":"672","volume":"58","author":"Bude\u010d","year":"2019","journal-title":"Acta Clin. Croat."},{"key":"10.1016\/j.jep.2026.121703_bib19","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jpba.2018.06.007","article-title":"Efficient extraction of proanthocyanidin from ginkgo biloba leaves employing rationally designed deep eutectic solvent-water mixture and evaluation of the antioxidant activity","volume":"158","author":"Cao","year":"2018","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"12","key":"10.1016\/j.jep.2026.121703_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/molecules23123214","article-title":"Tailor-made deep eutectic solvents for simultaneous extraction of five aromatic acids from ginkgo biloba leaves","volume":"23","author":"Cao","year":"2018","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2026.121703_bib21","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.jclepro.2017.03.140","article-title":"Tailor-made hydrophobic deep eutectic solvents for cleaner extraction of polyprenyl acetates from ginkgo biloba leaves","volume":"152","author":"Cao","year":"2017","journal-title":"J. Clean. Prod."},{"key":"10.1016\/j.jep.2026.121703_bib22","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jep.2020.113474","article-title":"Nrf-2 mediated heme oxygenase-1 activation contributes to the anti-inflammatory and renal protective effects of ginkgo biloba extract in diabetic nephropathy","volume":"266","author":"Chang","year":"2021","journal-title":"J. Ethnopharmacol."},{"issue":"3","key":"10.1016\/j.jep.2026.121703_bib23","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1007\/s00210-024-03515-8","article-title":"Deciphering the mechanisms underlying the neuroprotective potential of kaempferol: a comprehensive investigation","volume":"398","author":"Chaubey","year":"2025","journal-title":"Naunyn-Schmiedebergs Arch Pharmacol"},{"issue":"5","key":"10.1016\/j.jep.2026.121703_bib24","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1002\/ptr.7720","article-title":"Antiplatelet effect of ginkgo diterpene lactone meglumine injection in acute ischemic stroke: a randomized, double-blind, placebo-controlled clinical trial","volume":"37","author":"Chen","year":"2023","journal-title":"Phytother Res."},{"issue":"2","key":"10.1016\/j.jep.2026.121703_bib25","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.atherosclerosis.2010.11.010","article-title":"Nrf-2 mediated heme oxygenase-1 expression, an antioxidant-independent mechanism, contributes to anti-atherogenesis and vascular protective effects of ginkgo biloba extract","volume":"214","author":"Chen","year":"2011","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jep.2026.121703_bib26","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/1475-2840-11-49","article-title":"Ginkgo biloba extract reduces high-glucose-induced endothelial adhesion by inhibiting the redox-dependent interleukin-6 pathways","volume":"11","author":"Chen","year":"2012","journal-title":"Cardiovasc. Diabetol."},{"issue":"10","key":"10.1016\/j.jep.2026.121703_bib27","doi-asserted-by":"crossref","first-page":"4596","DOI":"10.1007\/s12011-023-04021-3","article-title":"Ginkgo biloba extract can antagonize subchronic arsenite exposure-induced hepatocyte senescence by inhibiting oxidative damage and inflammation in rats","volume":"202","author":"Chen","year":"2024","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.jep.2026.121703_bib28","doi-asserted-by":"crossref","first-page":"647","DOI":"10.2147\/DDDT.S191537","article-title":"Ginkgo biloba extract-761 protects myocardium by regulating akt\/nrf2 signal pathway","volume":"13","author":"Chen","year":"2019","journal-title":"Drug Des Devel Ther"},{"key":"10.1016\/j.jep.2026.121703_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.157155","article-title":"Yindan xinnaotong soft capsule improves post-ischemic stroke recovery by regulating CREB\/BDNF-mediated synaptic plasticity and CREB\/VEGFA-mediated angiogenesis","volume":"146","author":"Cheng","year":"2025","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2026.121703_bib30","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/162724","article-title":"Antihyperglycemic effect of ginkgo biloba extract in streptozotocin-induced diabetes in rats","volume":"2013","author":"Cheng","year":"2013","journal-title":"BioMed Res. Int."},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib31","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S0006-2952(03)00388-5","article-title":"Down-regulation of c-jun n-terminal kinase-activator protein-1 signaling pathway by ginkgo biloba extract in human peripheral blood t cells","volume":"66","author":"Cheng","year":"2003","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.jep.2026.121703_bib32","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.phrs.2018.11.027","article-title":"Ginkgetin, a biflavone from ginkgo biloba leaves, prevents adipogenesis through STAT5-mediated PPAR\u03b3 and c\/EBP\u03b1 regulation","volume":"139","author":"Cho","year":"2019","journal-title":"Pharmacol. Res."},{"issue":"1","key":"10.1016\/j.jep.2026.121703_bib33","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1186\/s12903-025-06385-5","article-title":"Gelatin nanofibrous scaffolds containing rutin nanoparticles: physicochemical properties, antibacterial action, and anti-inflammatory effect on dental pulp stem cells","volume":"25","author":"Dadgar","year":"2025","journal-title":"BMC Oral Health"},{"issue":"2","key":"10.1016\/j.jep.2026.121703_bib34","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1208\/s12248-012-9339-4","article-title":"Challenges in development of nanoparticle-based therapeutics","volume":"14","author":"Desai","year":"2012","journal-title":"AAPS J."},{"issue":"10","key":"10.1016\/j.jep.2026.121703_bib35","doi-asserted-by":"crossref","first-page":"176","DOI":"10.3390\/separations8100176","article-title":"Deep eutectic solvents (DESs) as green extraction media of beneficial bioactive phytochemicals","volume":"8","author":"Dheyab","year":"2021","journal-title":"Separations"},{"issue":"7","key":"10.1016\/j.jep.2026.121703_bib36","doi-asserted-by":"crossref","first-page":"8899","DOI":"10.1007\/s00210-025-03815-7","article-title":"Ginkgolide b regulates apoptosis, oxidative stress, and mitochondrial dysfunction in MPP(+)-induced SK-n-SH cells by targeting HDAC4\/JNK pathway","volume":"398","author":"Ding","year":"2025","journal-title":"Naunyn-Schmiedebergs Arch Pharmacol"},{"issue":"19_part_2","key":"10.1016\/j.jep.2026.121703_bib37","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1212\/01.wnl.0000303814.13509.db","article-title":"A randomized placebo-controlled trial of ginkgo biloba for the prevention of cognitive decline","volume":"70","author":"Dodge","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.jep.2026.121703_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.indcrop.2021.113462","article-title":"Efficient removal of ginkgolic acids from ginkgo biloba leaves crude extract by using hydrophobic deep eutectic solvents","volume":"166","author":"Dong","year":"2021","journal-title":"Ind. Crop. Prod."},{"key":"10.1016\/j.jep.2026.121703_bib39","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.neuroscience.2023.05.015","article-title":"A novel extract from ginkgo biloba inhibits neuroinflammation and maintains white matter integrity in experimental stroke","volume":"523","author":"Dong","year":"2023","journal-title":"Neuroscience"},{"key":"10.1016\/j.jep.2026.121703_bib40","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1196\/annals.1352.023","article-title":"Stabilization of mitochondrial membrane potential and improvement of neuronal energy metabolism by ginkgo biloba extract EGb 761","volume":"1056","author":"Eckert","year":"2005","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.jep.2026.121703_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.112964","article-title":"Chip-based serum proteomics approach to reveal the potential protein markers in the sub-acute stroke patients receiving the treatment of ginkgo diterpene lactone meglumine injection","volume":"260","author":"Fan","year":"2020","journal-title":"J. Ethnopharmacol."},{"issue":"3","key":"10.1016\/j.jep.2026.121703_bib42","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1093\/jat\/26.3.138","article-title":"Gas chromatography-mass spectrometry analysis of 4-o-methylpyridoxine (MPN) in the serum of patients with ginkgo seed poisoning","volume":"26","author":"Fujisawa","year":"2002","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.jep.2026.121703_bib43","doi-asserted-by":"crossref","first-page":"7295","DOI":"10.2147\/IJN.S493862","article-title":"Liposomal nanoparticle delivery of ginkgo flavone glycosides enhances SIRT1 activation and improves diabetic cardiomyopathy","volume":"20","author":"Gao","year":"2025","journal-title":"Int. J. Nanomed."},{"issue":"40","key":"10.1016\/j.jep.2026.121703_bib44","doi-asserted-by":"crossref","first-page":"22115","DOI":"10.1021\/acs.jafc.4c03783","article-title":"Orally administered ginkgolide c alleviates MPTP-induced neurodegeneration by suppressing neuroinflammation and oxidative stress through microbiota-gut-brain axis in mice","volume":"72","author":"Gao","year":"2024","journal-title":"J. Agric. Food Chem."},{"issue":"3","key":"10.1016\/j.jep.2026.121703_bib45","doi-asserted-by":"crossref","first-page":"244","DOI":"10.2174\/1570161120666220201160038","article-title":"The role of inflammation as a preponderant risk factor in cardiovascular diseases","volume":"20","author":"Garcia","year":"2022","journal-title":"Curr. Vasc. Pharmacol."},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib46","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.ejps.2012.07.016","article-title":"Inhibition of NF-\u03bab activation is associated with anti-inflammatory and anti-apoptotic effects of ginkgolide b in a mouse model of cerebral ischemia\/reperfusion injury","volume":"47","author":"Gu","year":"2012","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.jep.2026.121703_bib47","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6657206","article-title":"Ginkgo biloba extract EGB761 ameliorates the extracellular matrix accumulation and mesenchymal transformation of renal tubules in diabetic kidney disease by inhibiting endoplasmic reticulum stress","volume":"2021","author":"Han","year":"2021","journal-title":"BioMed Res. Int."},{"issue":"35","key":"10.1016\/j.jep.2026.121703_bib48","doi-asserted-by":"crossref","first-page":"40460","DOI":"10.1021\/acsomega.5c05859","article-title":"Exploration of the mechanism ofginkgo biloba leaves targeted angiogenesis against gastric cancer","volume":"10","author":"Han","year":"2025","journal-title":"ACS Omega"},{"issue":"1","key":"10.1016\/j.jep.2026.121703_bib49","doi-asserted-by":"crossref","first-page":"110","DOI":"10.62641\/aep.v53i1.1676","article-title":"Repetitive transcranial magnetic stimulation combined with ginkgo diterpene lactone meglumine injection recover cognitive and neurological functions of patients with acute ischemic stroke","volume":"53","author":"Hao","year":"2025","journal-title":"Actas Esp. Psiquiatri."},{"key":"10.1016\/j.jep.2026.121703_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.onano.2022.100048","article-title":"Scale-up polymeric-based nanoparticles drug delivery systems: development and challenges","volume":"7","author":"Herdiana","year":"2022","journal-title":"OpenNano"},{"issue":"9","key":"10.1016\/j.jep.2026.121703_bib52","first-page":"1316","article-title":"Protective effects of ginkgo biloba extract on rats during cerebral ischemia\/reperfusion","volume":"115","author":"Hu","year":"2002","journal-title":"Chin. Med. J. (Engl)."},{"key":"10.1016\/j.jep.2026.121703_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.117202","article-title":"The role of ginkgo folium on antitumor: bioactive constituents and the potential mechanism","volume":"321","author":"Hu","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121703_bib54","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1016\/j.ijbiomac.2020.05.129","article-title":"Comparison in bioactivity and characteristics of ginkgo biloba seed polysaccharides from four extract pathways","volume":"159","author":"Hu","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"issue":"2","key":"10.1016\/j.jep.2026.121703_bib55","doi-asserted-by":"crossref","DOI":"10.3390\/molecules30020409","article-title":"Screening of solvent systems for countercurrent chromatography separation of polar constituents from ginkgo biloba l. Seeds","volume":"30","author":"Hu","year":"2025","journal-title":"Molecules"},{"issue":"1","key":"10.1016\/j.jep.2026.121703_bib56","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s12959-025-00696-x","article-title":"The mechanisms of efficacy and safety of ginkgo biloba extract in acute ischemic stroke: a real-world study","volume":"23","author":"Huang","year":"2025","journal-title":"Thromb. J."},{"key":"10.1016\/j.jep.2026.121703_bib57","article-title":"Comparison of efficacy and safety of cilostazol\/extract of ginkgo biloba vs. Aspirin in carotid atherosclerosis in patients with diabetes mellitus","author":"Hwang","year":"2025","journal-title":"Diabetes Metab. J"},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib58","doi-asserted-by":"crossref","DOI":"10.31083\/FBE44344","article-title":"Targeting the LRRK2 g2019s mutation found in Parkinson'S disease: efficiency of biosynthesized solid lipid nanoparticles for therapeutic siRNA-mediated gene therapy","volume":"17","author":"Jagaran","year":"2025","journal-title":"Front Biosci (Elite Ed)"},{"issue":"2","key":"10.1016\/j.jep.2026.121703_bib59","doi-asserted-by":"crossref","first-page":"104","DOI":"10.14581\/jer.15018","article-title":"Ginkgotoxin induced seizure caused by vitamin b6 deficiency","volume":"5","author":"Jang","year":"2015","journal-title":"J Epilepsy Res"},{"issue":"10","key":"10.1016\/j.jep.2026.121703_bib60","doi-asserted-by":"crossref","first-page":"588","DOI":"10.31083\/ph.2016.6576","article-title":"Ginkgolide a inhibits lipopolysaccharide-induced inflammatory response in human coronary artery endothelial cells via downregulation of TLR4-NF-\u03bab signaling through PI3k\/akt pathway","volume":"71","author":"Jian","year":"2016","journal-title":"Pharmazie"},{"issue":"11","key":"10.1016\/j.jep.2026.121703_bib61","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1093\/jpp\/rgad075","article-title":"Ginkgo biloba extract ameliorates hyperglycaemia-induced enteric glial cell injury via regulation of the TLR2-related pathway","volume":"75","author":"Jiang","year":"2023","journal-title":"J. Pharm. Pharmacol."},{"issue":"7","key":"10.1016\/j.jep.2026.121703_bib62","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1111\/j.1745-7254.2005.00106.x","article-title":"Expression of pro-inflammatory and anti-inflammatory cytokines in brain of atherosclerotic rats and effects of ginkgo biloba extract","volume":"26","author":"Jiao","year":"2005","journal-title":"Acta Pharmacol. Sin."},{"issue":"9","key":"10.1016\/j.jep.2026.121703_bib63","first-page":"930","article-title":"Effects of ginkgo biloba extract on expressions of IL-1beta, TNF-alpha, and IL-10 in u937 foam cells","volume":"42","author":"Jiao","year":"2007","journal-title":"Yao Xue Xue Bao"},{"issue":"11","key":"10.1016\/j.jep.2026.121703_bib64","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1038\/s41565-024-01754-7","article-title":"A translational framework to DELIVER nanomedicines to the clinic","volume":"19","author":"Joyce","year":"2024","journal-title":"Nat. Nanotechnol."},{"issue":"17","key":"10.1016\/j.jep.2026.121703_bib65","doi-asserted-by":"crossref","DOI":"10.3390\/foods14172958","article-title":"Ultrasonic-assisted ginkgo biloba leaves extract as natural antioxidant on oxidative stability of oils during deep-frying","volume":"14","author":"Kang","year":"2025","journal-title":"Foods"},{"key":"10.1016\/j.jep.2026.121703_bib66","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.jconrel.2016.02.026","article-title":"Nanocarriers for the treatment of glioblastoma multiforme: current state-of-the-art","volume":"227","author":"Karim","year":"2016","journal-title":"J. Control. Release"},{"issue":"6","key":"10.1016\/j.jep.2026.121703_bib67","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.cptl.2022.06.011","volume":"14","author":"Klausner","year":"2022","journal-title":"Curr. Pharm. Teach. Learn."},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib68","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1142\/S0192415X10008196","article-title":"Gingko biloba extract (EGb 761) prevents cerebral ischemia-induced p70s6 kinase and s6 phosphorylation","volume":"38","author":"Koh","year":"2010","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.jep.2026.121703_bib69","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.phytol.2020.06.012","article-title":"Structural characterization of ginkgo biloba l. Leaves cyclopeptides and anti-inflammatory potency evaluation in human umbilical vein endothelial cells","volume":"39","author":"Kong","year":"2020","journal-title":"Phytochem. Lett."},{"issue":"3","key":"10.1016\/j.jep.2026.121703_bib70","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1097\/APO.0000000000000279","article-title":"Ginkgo biloba extract in ophthalmic and systemic disease, with a focus on normal-tension glaucoma","volume":"9","author":"Labkovich","year":"2020","journal-title":"Asia-Pac. J. Ophthalmol."},{"key":"10.1016\/j.jep.2026.121703_bib71","doi-asserted-by":"crossref","DOI":"10.1016\/j.ultsonch.2025.107254","article-title":"Ultrasound-assisted deep eutectic solvent extraction of flavonol glycosides from ginkgo biloba: optimization of efficiency and mechanism","volume":"114","author":"Lai","year":"2025","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.jep.2026.121703_bib72","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.brainres.2011.10.005","article-title":"Neuroprotective effects of bilobalide are accompanied by a reduction of ischemia-induced glutamate release in vivo","volume":"1425","author":"Lang","year":"2011","journal-title":"Brain Res."},{"key":"10.1016\/j.jep.2026.121703_bib73","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3389\/fphar.2025.1495997","article-title":"Proanthocyanidins from ginkgo extract EGb 761\u00ae improve bioenergetics and stimulate neurite outgrowth in vitro","volume":"16","author":"Lejri","year":"2025","journal-title":"Front. Pharmacol."},{"issue":"8","key":"10.1016\/j.jep.2026.121703_bib74","first-page":"12","article-title":"Effects of gingko biloba and milk thistle extracts on biomarkers of antioxidants status and liver function in healthy dogs","volume":"12","author":"Lertpatarakomol","year":"2025","journal-title":"Vet. Sci."},{"key":"10.1016\/j.jep.2026.121703_bib75","first-page":"12","article-title":"Phloretic acid requires the insulin\/IGF-1 pathway and autophagy to enhance stress resistance and extend the lifespan of caenorhabditis elegans","volume":"15","author":"Li","year":"2024","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.121703_bib76","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116537","article-title":"Ginkgolide c attenuates cerebral ischemia\/reperfusion-induced inflammatory impairments by suppressing CD40\/NF-kappab pathway","volume":"312","author":"Li","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121703_bib77","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.2147\/JIR.S302934","article-title":"Ginkgo biloba extract 50 (GBE50) ameliorates insulin resistance, hepatic steatosis and liver injury in high fat diet-fed mice","volume":"14","author":"Li","year":"2021","journal-title":"J. Inflamm. Res."},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib78","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1080\/09168451.2018.1553608","article-title":"Ginkgetin exerts anti-inflammatory effects on cerebral ischemia\/reperfusion-induced injury in a rat model via the TLR4\/NF-\u03bab signaling pathway","volume":"83","author":"Li","year":"2019","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1016\/j.jep.2026.121703_bib79","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2019.112365","article-title":"Ginkgo diterpene lactones inhibit cerebral ischemia\/reperfusion induced inflammatory response in astrocytes via TLR4\/NF-kappab pathway in rats","volume":"249","author":"Li","year":"2020","journal-title":"J. Ethnopharmacol."},{"issue":"12","key":"10.1016\/j.jep.2026.121703_bib80","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s00604-019-3885-8","article-title":"Preparation of deep eutectic solvent-based hexagonal boron nitride-molecularly imprinted polymer nanoparticles for solid phase extraction of flavonoids","volume":"186","author":"Li","year":"2019","journal-title":"Mikrochim. Acta"},{"key":"10.1016\/j.jep.2026.121703_bib81","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.120059","article-title":"Inhibition of mitochondrial oxidative stress and apoptosis in the protection of ginkgo biloba extract 50 against cognitive impairment","volume":"351","author":"Li","year":"2025","journal-title":"J. Ethnopharmacol."},{"issue":"Pt B","key":"10.1016\/j.jep.2026.121703_bib83","article-title":"Structural characterization of a alpha-d-glucan from ginkgo biloba seeds and its protective effects on non-alcoholic fatty liver disease in mice","volume":"349","author":"Liang","year":"2025","journal-title":"Carbohydr. Polym."},{"issue":"3","key":"10.1016\/j.jep.2026.121703_bib84","doi-asserted-by":"crossref","DOI":"10.3390\/molecules29030737","article-title":"Combination of a deep eutectic solvent and macroporous resin for green recovery of iridoids, chlorogenic acid, and flavonoids from eucommia ulmoides leaves","volume":"29","author":"Liao","year":"2024","journal-title":"Molecules"},{"issue":"12","key":"10.1016\/j.jep.2026.121703_bib85","doi-asserted-by":"crossref","DOI":"10.31083\/FBL46724","article-title":"Ginkgolide b promotes angiogenesis after oxygen-glucose deprivation by regulating AKT1 in bend.3 cells","volume":"30","author":"Liao","year":"2025","journal-title":"Front. Biosci."},{"key":"10.1016\/j.jep.2026.121703_bib86","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.ejmech.2019.04.075","article-title":"Therapeutic potential of natural compounds in inflammation and chronic venous insufficiency","volume":"176","author":"Lichota","year":"2019","journal-title":"Eur. J. Med. Chem."},{"issue":"5","key":"10.1016\/j.jep.2026.121703_bib87","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1021\/jf062945r","article-title":"Ginkgo biloba extract inhibits endotoxin-induced human aortic smooth muscle cell proliferation via suppression of toll-like receptor 4 expression and NADPH oxidase activation","volume":"55","author":"Lin","year":"2007","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jep.2026.121703_bib88","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.3389\/fphar.2019.01688","article-title":"An updated review of randomized clinical trials testing the improvement of cognitive function of ginkgo biloba extract in healthy people and alzheimer's patients","volume":"10","author":"Liu","year":"2020","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.121703_bib89","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2020.113704","article-title":"Advances in the chemical constituents and chemical analysis of ginkgo biloba leaf, extract, and phytopharmaceuticals","volume":"193","author":"Liu","year":"2021","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib90","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1142\/S0192415X24500435","article-title":"Comprehensive exploration of the neuroprotective mechanisms of ginkgo biloba leaves in treating neurological disorders","volume":"52","author":"Liu","year":"2024","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.jep.2026.121703_bib91","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2025.117189","article-title":"Tea saponin assisted micellar extraction combined with in-situ aqueous two phase enrichment of flavonoids and lactones from functional food","volume":"220","author":"Liu","year":"2025","journal-title":"Food Res. Int."},{"issue":"8","key":"10.1016\/j.jep.2026.121703_bib93","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000014643","article-title":"Ginkgo leaf extract and dipyridamole injection as adjuvant treatment for acute cerebral infarction: protocol for systemic review and meta-analysis of randomized controlled trials","volume":"98","author":"Liu","year":"2019","journal-title":"Medicine. (Baltimore)."},{"issue":"11","key":"10.1016\/j.jep.2026.121703_bib95","doi-asserted-by":"crossref","first-page":"9194","DOI":"10.3390\/molecules16119194","article-title":"Effect of ginkgo biloba extract 50 on immunity and antioxidant enzyme activities in ischemia reperfusion rats","volume":"16","author":"Lu","year":"2011","journal-title":"Molecules"},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib96","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0321804","article-title":"Impact of ginkgo biloba drug interactions on bleeding risk and coagulation profiles: a comprehensive analysis","volume":"20","author":"Mai","year":"2025","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.jep.2026.121703_bib97","first-page":"10","article-title":"Bilobalide attenuates lipopolysaccharide - induced HepG2 cell injury by inhibiting TLR4 - NF - \u03bab signaling via the PI3k\/akt pathway","volume":"27","author":"Mao","year":"2024","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.jep.2026.121703_bib98","article-title":"Natural deep eutectic systems-based ginkgo biloba extracts: a natural and sustainable solution for skin care","volume":"48","author":"Marques","year":"2025","journal-title":"Sustain. Chem. Pharm."},{"issue":"1","key":"10.1016\/j.jep.2026.121703_bib99","doi-asserted-by":"crossref","first-page":"94","DOI":"10.18433\/J3PS37","article-title":"Ginkgo extract EGb761 confers neuroprotection by reduction of glutamate release in ischemic brain","volume":"15","author":"Mdzinarishvili","year":"2012","journal-title":"J. Pharm. Pharm. Sci."},{"issue":"1","key":"10.1016\/j.jep.2026.121703_bib100","first-page":"1","article-title":"Review of ginkgo biloba-induced toxicity, from experimental studies to human case reports","volume":"35","author":"Mei","year":"2017","journal-title":"J. Environ. Sci. Health C Environ. Carcinog. Ecotoxicol. Rev."},{"key":"10.1016\/j.jep.2026.121703_bib101","doi-asserted-by":"crossref","DOI":"10.1016\/j.ultsonch.2023.106588","article-title":"An integrated process by ultrasonic enhancement in the deep eutectic solvents system for extraction and separation of chlorogenic acid from eucommia ulmoides leaves","volume":"99","author":"Meng","year":"2023","journal-title":"Ultrason. Sonochem."},{"issue":"2","key":"10.1016\/j.jep.2026.121703_bib102","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1046\/j.1528-1157.2001.33100.x","article-title":"Generalized convulsions after consuming a large amount of gingko nuts","volume":"42","author":"Miwa","year":"2001","journal-title":"Epilepsia"},{"key":"10.1016\/j.jep.2026.121703_bib103","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2025.115455","article-title":"Standardized extract of ginkgo biloba induced memory consolidation in female mice with hypofunction of vesicular acetylcholine transporter","volume":"482","author":"Muratori","year":"2025","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.jep.2026.121703_bib104","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.156327","article-title":"Ginkgo biloba extract EGb 761(r) ameliorates cognitive impairment and alleviates TNFalpha response in 5xFAD Alzheimer'S disease model mice","volume":"136","author":"Nguyen","year":"2025","journal-title":"Phytomedicine"},{"issue":"9","key":"10.1016\/j.jep.2026.121703_bib105","doi-asserted-by":"crossref","DOI":"10.3390\/cells13090732","article-title":"L-carnitine and ginkgo biloba supplementation in vivo ameliorates HCD-induced steatohepatitis and dyslipidemia by regulating hepatic metabolism","volume":"13","author":"Nofal","year":"2024","journal-title":"Cells"},{"key":"10.1016\/j.jep.2026.121703_bib106","article-title":"Ginkgo biloba: a treasure of functional phytochemicals with multimedicinal applications. evid.-based complement altern","volume":"2022","author":"Noor-E-Tabassum","year":"2022","journal-title":"Med."},{"issue":"3","key":"10.1016\/j.jep.2026.121703_bib108","first-page":"207","article-title":"Protective and therapeutic role of ginkgo biloba extract through TRPV1 channels in an in vitro Alzheimer'S disease model","volume":"60","author":"Ozsimsek","year":"2023","journal-title":"Noropsikiyatri Ars"},{"key":"10.1016\/j.jep.2026.121703_bib109","article-title":"Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations","volume":"3","author":"Palmelund","year":"2021","journal-title":"Int. J. Pharm. X"},{"key":"10.1016\/j.jep.2026.121703_bib110","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejps.2026.107484","article-title":"Deep eutectic systems as enabling pharmaceutical formulations: mechanisms and applications","volume":"220","author":"Panbachi","year":"2026","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.jep.2026.121703_bib111","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2025.118472","article-title":"Ginkgolide a enhances cognition and reduces amyloid-beta by activating autophagy in the murine 5xFAD Alzheimer'S disease model","volume":"191","author":"Park","year":"2025","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2026.121703_bib112","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.109552","article-title":"Anti-inflammatory effects of rhodiola rosea l.: a review","volume":"121","author":"Pu","year":"2020","journal-title":"Biomed. Pharmacother."},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib113","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e26093","article-title":"Ginkgo biloba extract alleviates CCl 4 -induced acute liver injury by regulating PI3k\/AKT signaling pathway","volume":"10","author":"Pu","year":"2024","journal-title":"Heliyon"},{"key":"10.1016\/j.jep.2026.121703_bib114","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2021.107076","article-title":"Effective extraction methods based on hydrophobic deep eutectic solvent coupled with functional molecularly imprinted polymers: application on quercetagetin extraction from natural medicine and blood","volume":"174","author":"Quan","year":"2022","journal-title":"Microchem. J."},{"issue":"12","key":"10.1016\/j.jep.2026.121703_bib115","doi-asserted-by":"crossref","first-page":"987","DOI":"10.7150\/ijms.13339","article-title":"Extract of ginkgo biloba ameliorates streptozotocin-induced type 1 diabetes mellitus and high-fat diet-induced type 2 diabetes mellitus in mice","volume":"12","author":"Rhee","year":"2015","journal-title":"Int. J. Med. Sci."},{"issue":"3","key":"10.1016\/j.jep.2026.121703_bib116","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1080\/15622975.2024.2446830","article-title":"Ginkgo biloba extract EGb 761 is safe and effective in the treatment of mild dementia - a meta-analysis of patient subgroups in randomised controlled trials","volume":"26","author":"Riepe","year":"2025","journal-title":"World J. Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.jep.2026.121703_bib117","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.immuni.2021.12.013","article-title":"Inflammation in obesity, diabetes, and related disorders","volume":"55","author":"Rohm","year":"2022","journal-title":"Immunity"},{"issue":"5","key":"10.1016\/j.jep.2026.121703_bib118","doi-asserted-by":"crossref","first-page":"541","DOI":"10.2174\/156720505774932287","article-title":"A randomized, double-blind, placebo-controlled trial of two doses of ginkgo biloba extract in dementia of the alzheimer's type","volume":"2","author":"Schneider","year":"2005","journal-title":"Curr. Alzheimer Res."},{"key":"10.1016\/j.jep.2026.121703_bib119","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2025.1673248","article-title":"Proanthocyanidins from ginkgo biloba extract EGb 761((r)) exert antioxidative activity in vitro and antiamnesic activity in vivo","volume":"16","author":"Sens-Albert","year":"2025","journal-title":"Front. Pharmacol."},{"issue":"3","key":"10.1016\/j.jep.2026.121703_bib120","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1093\/toxres\/tfaf075","article-title":"Hepatoprotective mechanisms of ginkgo-biloba and dandelion extracts : antioxidant activity and modulation of TNF-\u03b1 and p53 pathways in thioacetamide-induced liver injury","volume":"14","author":"Shaaban","year":"2025","journal-title":"Toxicol. Res."},{"key":"10.1016\/j.jep.2026.121703_bib121","first-page":"206","article-title":"Targeted therapy of kidney disease with nanoparticle drug delivery materials","volume":"37","author":"Shang","year":"2024","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.jep.2026.121703_bib122","doi-asserted-by":"crossref","first-page":"100","DOI":"10.3389\/fendo.2019.00100","article-title":"Efficacy of co-administration of liuwei dihuang pills and ginkgo biloba tablets on albuminuria in type 2 diabetes: a 24-month, multicenter, double-blind, placebo-controlled, randomized clinical trial","volume":"10","author":"Shi","year":"2019","journal-title":"Front. Endocrinol."},{"issue":"48","key":"10.1016\/j.jep.2026.121703_bib123","doi-asserted-by":"crossref","first-page":"17175","DOI":"10.1002\/anie.201908386","article-title":"The ultrafast and continuous fabrication of a polydimethylsiloxane membrane by ultraviolet-induced polymerization","volume":"58","author":"Si","year":"2019","journal-title":"Angew Chem. Int. Ed. Engl."},{"issue":"13\u201314","key":"10.1016\/j.jep.2026.121703_bib124","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1007\/s10354-007-0426-6","article-title":"Ginkgo biloba (EGb 761) in arteriosclerosis prophylaxis","volume":"157","author":"Siegel","year":"2007","journal-title":"Wien. Med. Wochenschr."},{"key":"10.1016\/j.jep.2026.121703_bib125","doi-asserted-by":"crossref","DOI":"10.1016\/j.fpsl.2025.101581","article-title":"Facile and green synthesis of multifunctional nitrogen-doped carbon quantum dots from ginkgo biloba leaves for antibacterial, antioxidant, and bioactive coating applications","volume":"51","author":"Singh","year":"2025","journal-title":"Food Packag. Shelf Life"},{"issue":"6","key":"10.1016\/j.jep.2026.121703_bib126","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.fitote.2008.05.007","article-title":"Biology and chemistry of ginkgo biloba","volume":"79","author":"Singh","year":"2008","journal-title":"Fitoterapia"},{"issue":"7","key":"10.1016\/j.jep.2026.121703_bib127","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26073066","article-title":"Dual biopolymer layer using nanoparticles with active substance enclosed in microcapsules: innovative solution for slow release of ginkgo biloba l. Extract for potential therapies","volume":"26","author":"Sitarek","year":"2025","journal-title":"Int. J. Mol. Sci."},{"issue":"7","key":"10.1016\/j.jep.2026.121703_bib128","doi-asserted-by":"crossref","first-page":"4093","DOI":"10.1111\/1750-3841.17126","article-title":"Thermal fixation technologies affect phenolic profile, ginkgolides, bilobalide, product quality, and ginkgolic acids in ginkgo biloba leaf tea","volume":"89","author":"Soetanto","year":"2024","journal-title":"J. Food Sci."},{"issue":"12","key":"10.1016\/j.jep.2026.121703_bib129","doi-asserted-by":"crossref","first-page":"6407","DOI":"10.1007\/s12010-022-04012-5","article-title":"Protective effects of the bilobalide on retinal oxidative stress and inflammation in streptozotocin-induced diabetic rats","volume":"194","author":"Su","year":"2022","journal-title":"Appl. Biochem. Biotechnol."},{"issue":"11","key":"10.1016\/j.jep.2026.121703_bib130","doi-asserted-by":"crossref","DOI":"10.3390\/foods14111890","article-title":"Quercetin-loaded ginkgo starch nanoparticles: a promising strategy to improve bioactive delivery and cellular homeostasis in functional foods","volume":"14","author":"Sun","year":"2025","journal-title":"Foods"},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib131","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s00424-023-02790-3","article-title":"Ginkgolide b caused the activation of the akt\/eNOS pathway through the antioxidant effect of SOD1 in the diabetic aorta","volume":"475","author":"Taguchi","year":"2023","journal-title":"Pflugers Arch"},{"issue":"1","key":"10.1016\/j.jep.2026.121703_bib132","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jep.2009.04.017","article-title":"Protective effects of serum containing ginkgo biloba extract on glomerulosclerosis in rat mesangial cells","volume":"124","author":"Tang","year":"2009","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121703_bib133","doi-asserted-by":"crossref","first-page":"189","DOI":"10.2147\/NSA.S478533","article-title":"Nano-ayurvedic medicine approaches using ginkgo biloba-phytochemicals functionalized gold nanoparticles against breast cancer","volume":"17","author":"Thipe","year":"2024","journal-title":"Nanotechnol. Sci. Appl."},{"key":"10.1016\/j.jep.2026.121703_bib134","article-title":"Ginkgo biloba leaf extract attenuates atherosclerosis in streptozotocin-induced diabetic ApoE-\/- mice by inhibiting endoplasmic reticulum stress via restoration of autophagy through the mTOR signaling pathway","volume":"2019","author":"Tian","year":"2019","journal-title":"Oxidative Med. Cell. Longev"},{"issue":"6","key":"10.1016\/j.jep.2026.121703_bib135","doi-asserted-by":"crossref","first-page":"3321","DOI":"10.1007\/s00415-024-12272-w","article-title":"Efficacy of ginkgo diterpene lactone meglumine on cognitive function in patients with acute ischemic stroke: a predefined exploratory analysis of a multicenter, double-blind, randomized controlled trial","volume":"271","author":"Tian","year":"2024","journal-title":"J. Neurol."},{"issue":"1","key":"10.1016\/j.jep.2026.121703_bib136","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s12955-024-02315-1","article-title":"Effect of ginkgo diterpene lactone meglumine on the quality of life in patients with acute ischemic stroke","volume":"22","author":"Tian","year":"2024","journal-title":"Health Qual. Life Outcomes"},{"issue":"3","key":"10.1016\/j.jep.2026.121703_bib138","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1093\/cvr\/cvq226","article-title":"EGb761 ameliorates the formation of foam cells by regulating the expression of SR-a and ABCA1: role of haem oxygenase-1","volume":"88","author":"Tsai","year":"2010","journal-title":"Cardiovasc. Res."},{"issue":"Suppl. l_10","key":"10.1016\/j.jep.2026.121703_bib139","doi-asserted-by":"crossref","first-page":"x12","DOI":"10.1093\/annonc\/mdz381","article-title":"Efficacy of PI3k inhibitors in advanced breast cancer","volume":"30","author":"Verret","year":"2019","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.jep.2026.121703_bib140","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.phymed.2024.156245","article-title":"Ginkgo biloba extract alleviates deltamethrin-induced testicular injury by upregulating SKP2 and inhibiting beclin1-independent autophagy","volume":"135","author":"Wang","year":"2024","journal-title":"Phytomedicine"},{"issue":"6","key":"10.1016\/j.jep.2026.121703_bib141","doi-asserted-by":"crossref","DOI":"10.3892\/mmr.2021.12096","article-title":"Ginkgolide b-induced AMPK pathway activation protects astrocytes by regulating endoplasmic reticulum stress, oxidative stress and energy metabolism induced by abeta1-42","volume":"23","author":"Wang","year":"2021","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.jep.2026.121703_bib142","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.119416","article-title":"Ginkgo diterpene lactone meglumine for functional recovery in patients with acute ischemic stroke: a systematic review and meta-analysis","volume":"342","author":"Wang","year":"2025","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.jep.2026.121703_bib147","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1002\/jnr.23306","article-title":"Neuroprotection against permanent focal cerebral ischemia by ginkgolides a and b is associated with obstruction of the mitochondrial apoptotic pathway via inhibition of c - jun n - terminal kinase in rats","volume":"92","author":"Wang","year":"2014","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.jep.2026.121703_bib148","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.brainres.2008.07.102","article-title":"Protective effect of ginkgolids (a plus b) is associated with inhibition of NIK\/IKK\/I\u03baB\/NF-\u03bab signaling pathway in a rat model of permanent focal cerebral ischemia","volume":"1234","author":"Wang","year":"2008","journal-title":"Brain Res."},{"issue":"6","key":"10.1016\/j.jep.2026.121703_bib150","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1002\/ptr.7439","article-title":"Ginkgo biloba extract ameliorates atherosclerosis via rebalancing gut flora and microbial metabolism","volume":"36","author":"Wang","year":"2022","journal-title":"Phytother Res."},{"issue":"3","key":"10.1016\/j.jep.2026.121703_bib151","first-page":"13","article-title":"Mechanism of total ginkgo biloba flavone mediating the inflammation and autophagy in lipopolysaccharide-induced human coronary artery endothelial cells through TLR4\/PI3k signaling pathway","volume":"18","author":"Wen","year":"2025","journal-title":"J. Radiat. Res. Appl. Sci."},{"issue":"7","key":"10.1016\/j.jep.2026.121703_bib152","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.addr.2011.10.007","article-title":"Nanotechnological advances for the delivery of CNS therapeutics","volume":"64","author":"Wong","year":"2012","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"2","key":"10.1016\/j.jep.2026.121703_bib153","doi-asserted-by":"crossref","first-page":"6387","DOI":"10.4238\/2015.June.11.14","article-title":"Effect of ginkgo biloba extract on apoptosis of brain tissues in rats with acute cerebral infarction and related gene expression","volume":"14","author":"Wu","year":"2015","journal-title":"Genet. Mol. Res."},{"key":"10.1016\/j.jep.2026.121703_bib154","doi-asserted-by":"crossref","DOI":"10.1016\/j.indcrop.2024.118865","article-title":"Removal of ginkgotoxins from the ginkgo biloba seed powder by enzymatic degradation with the laccase-syringaldehyde system","volume":"217","author":"Wu","year":"2024","journal-title":"Ind. Crop. Prod."},{"key":"10.1016\/j.jep.2026.121703_bib155","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.119734","article-title":"Hyperacute intervention with DGMI for optimized stroke recovery: modulating immune and inflammatory pathways in motor and sensory cortices","volume":"347","author":"Wu","year":"2025","journal-title":"J. Ethnopharmacol."},{"issue":"8","key":"10.1016\/j.jep.2026.121703_bib156","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1371\/journal.pone.0307735","article-title":"Ginkgo biloba extract inhibits hippocampal neuronal injury caused by mitochondrial oxidative stress in a rat model of Alzheimer'S disease","volume":"19","author":"Xia","year":"2024","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.jep.2026.121703_bib157","doi-asserted-by":"crossref","DOI":"10.3390\/cells11030479","article-title":"Can we use ginkgo biloba extract to treat Alzheimer'S disease? Lessons from preclinical and clinical studies","volume":"11","author":"Xie","year":"2022","journal-title":"Cells"},{"issue":"46","key":"10.1016\/j.jep.2026.121703_bib158","doi-asserted-by":"crossref","first-page":"14718","DOI":"10.1021\/acs.jafc.2c06177","article-title":"Orally administered ginkgolide c attenuates DSS-induced colitis by maintaining gut barrier integrity, inhibiting inflammatory responses, and regulating intestinal flora","volume":"70","author":"Xu","year":"2022","journal-title":"J. Agric. Food Chem."},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib160","first-page":"1809","article-title":"Ginkgo biloba extract protects diabetic rats against cerebral ischemia-reperfusion injury by suppressing oxidative stress and upregulating the expression of glutamate transporter 1","volume":"21","author":"Yan","year":"2020","journal-title":"Mol. Med. Rep."},{"issue":"3","key":"10.1016\/j.jep.2026.121703_bib161","doi-asserted-by":"crossref","first-page":"315","DOI":"10.15255\/CABEQ.2017.1146","article-title":"Efficient extraction of bioactive flavonoids from ginkgo biloba leaves using deep eutectic solvent\/water mixture as green media","volume":"32","author":"Yang","year":"2018","journal-title":"Chem. Biochem. Eng. Q."},{"key":"10.1016\/j.jep.2026.121703_bib162","article-title":"Efficacy of ginkgo biloba extract in amyloid PET-positive patients with mild cognitive impairment","volume":"16","author":"Yang","year":"2025","journal-title":"Front. Neurol."},{"key":"10.1016\/j.jep.2026.121703_bib163","first-page":"7","article-title":"Efficacy of ginkgo biloba as an adjunct to donepezil in amyloid PET-positive alzheimer's patients","volume":"16","author":"Yang","year":"2025","journal-title":"Front. Neurol."},{"issue":"5","key":"10.1016\/j.jep.2026.121703_bib164","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1021\/acschembio.6b00762","article-title":"Systematic investigation of ginkgo biloba leaves for treating cardio-cerebrovascular diseases in an animal model","volume":"12","author":"Yang","year":"2017","journal-title":"ACS Chem. Biol."},{"issue":"1","key":"10.1016\/j.jep.2026.121703_bib165","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jep.2011.04.027","article-title":"Effect of ginkgolide b on striatal extracellular amino acids in middle cerebral artery occluded rats","volume":"136","author":"Yang","year":"2011","journal-title":"J. Ethnopharmacol."},{"issue":"Pt 3","key":"10.1016\/j.jep.2026.121703_bib166","article-title":"Ginkgo biloba extract safety: insights from a real-world pharmacovigilance study of FDA adverse event reporting system (FAERS) events","volume":"337","author":"Yao","year":"2025","journal-title":"J. Ethnopharmacol."},{"issue":"8","key":"10.1016\/j.jep.2026.121703_bib167","first-page":"1138","article-title":"Ginkgo biloba leaf extract (EGb-761) elicits neuroprotection against cerebral ischemia\/reperfusion injury by enhancement of autophagy flux in neurons in the penumbra","volume":"24","author":"Yihao","year":"2021","journal-title":"Iran. J. Basic Med. Sci."},{"issue":"2","key":"10.1016\/j.jep.2026.121703_bib168","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1002\/pca.3286","article-title":"Study on network pharmacology ofginkgo biloba extract against ischaemic stroke mechanism and establishment of UPLC\u2010MS\/MS methods for simultaneous determination of 19 main active components","volume":"35","author":"Yin","year":"2024","journal-title":"Phytochem. Anal."},{"key":"10.1016\/j.jep.2026.121703_bib170","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.155088","article-title":"New insight into the mechanisms of ginkgo biloba leaves in the treatment of cancer","volume":"122","author":"Yu","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2026.121703_bib171","doi-asserted-by":"crossref","DOI":"10.1016\/j.indcrop.2025.120563","article-title":"Tannic acid-stabilized ginkgo biloba l. Polyprenol nanoemulsion: preparation, mechanism, bacterial therapy insights","volume":"225","author":"Yuan","year":"2025","journal-title":"Ind. Crop. Prod."},{"issue":"22","key":"10.1016\/j.jep.2026.121703_bib172","first-page":"4486","article-title":"[effect of ginkgo biloba extract (EGb50) on mitochondrial function in SH-SY5y cells after hypoxia\/reoxygenation injury","volume":"43","author":"Yuan","year":"2018","journal-title":"Zhongguo Zhongyao Zazhi"},{"key":"10.1016\/j.jep.2026.121703_bib173","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneuroim.2023.578101","article-title":"Ginkgo biloba extract (EGb-761) confers neuroprotection against ischemic stroke by augmenting autophagic\/lysosomal signaling pathway","volume":"382","author":"Zang","year":"2023","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jep.2026.121703_bib174","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneuroim.2023.578101","article-title":"Ginkgo biloba extract (EGb-761) confers neuroprotection against ischemic stroke by augmenting autophagic\/lysosomal signaling pathway","volume":"382","author":"Zang","year":"2023","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.jep.2026.121703_bib175","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.145569","article-title":"Investigating the potential of quercetin-loaded chitosan-coated lipid carriers as an oral nanoplatform for depression management","volume":"319","author":"Zewail","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jep.2026.121703_bib176","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ijbiomac.2025.145569","article-title":"Investigating the potential of quercetin-loaded chitosan-coated lipid carriers as an oral nanoplatform for depression management","volume":"319","author":"Zewail","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jep.2026.121703_bib177","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1407669","article-title":"Shuxuening injection for treating acute ischemic stroke: a PRISMA-compliant systematic review and meta-analysis of randomized controlled trials","volume":"15","author":"Zhan","year":"2024","journal-title":"Front. Pharmacol."},{"issue":"3","key":"10.1016\/j.jep.2026.121703_bib178","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.procbio.2015.12.008","article-title":"Enzymolysis-based ultrasound extraction and antioxidant activities of polyprenol lipids from ginkgo biloba leaves","volume":"51","author":"Zhang","year":"2016","journal-title":"Process Biochem"},{"key":"10.1016\/j.jep.2026.121703_bib179","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.chroma.2019.01.047","article-title":"Separation of polyprenols from ginkgo biloba leaves by a nano silica-based adsorbent containing silver ions","volume":"1590","author":"Zhang","year":"2019","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jep.2026.121703_bib180","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.fbio.2025.106892","article-title":"Extraction and characterization of proanthocyanidins from agricultural waste ginkgo biloba seed exocarp : structural , physicochemical and functional properties","volume":"69","author":"Zhang","year":"2025","journal-title":"Food Biosci."},{"key":"10.1016\/j.jep.2026.121703_bib181","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/2408598","article-title":"Ginkgo biloba extract reduces cardiac and brain inflammation in rats fed a HFD and exposed to chronic mental stress through NF-kappab inhibition","volume":"2022","author":"Zhang","year":"2022","journal-title":"Mediat. Inflamm."},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib183","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/jpp\/rgaa013","article-title":"A simple and effective method for the preparation of high-purity shikimic acid from chromatography wash effluent of ginkgo biloba leaf extract by macroporous resin considering the effect of varying feed solution compositions","volume":"73","author":"Zhang","year":"2021","journal-title":"J. Pharm. Pharmacol."},{"issue":"21\u201322","key":"10.1016\/j.jep.2026.121703_bib184","first-page":"1821","article-title":"Advancements in nanomedicine delivery systems: unraveling immune regulation strategies for tumor immunotherapy","volume":"19","author":"Zhang","year":"2024","journal-title":"Nanomedicine"},{"key":"10.1016\/j.jep.2026.121703_bib186","doi-asserted-by":"crossref","first-page":"518","DOI":"10.3389\/fphar.2018.00518","article-title":"Ginkgo biloba extract inhibits astrocytic lipocalin-2 expression and alleviates neuroinflammatory injury via the JAK2\/STAT3 pathway after ischemic brain stroke","volume":"9","author":"Zhang","year":"2018","journal-title":"Front. Pharmacol."},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib187","first-page":"165","article-title":"The contents of terpene trilactone and flavonoid in leaves of seedlings from ancient female ginkgo trees in China. Hortic","volume":"3","author":"Zhang","year":"2017","journal-title":"Plant J."},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib188","first-page":"165","article-title":"The contents of terpene trilactone and flavonoid in leaves of seedlings from ancient female ginkgo trees in China. Hortic","volume":"3","author":"Zhang","year":"2017","journal-title":"Plant J."},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib189","first-page":"165","article-title":"The contents of terpene trilactone and flavonoid in leaves of seedlings from ancient female ginkgo trees in China. Hortic","volume":"3","author":"Zhang","year":"2017","journal-title":"Plant J."},{"issue":"1","key":"10.1016\/j.jep.2026.121703_bib190","doi-asserted-by":"crossref","first-page":"301","DOI":"10.3390\/molecules28010301","article-title":"Applications of molecular imprinting technology in the study of traditional chinese medicine","volume":"28","author":"Zhang","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2026.121703_bib191","article-title":"The efficacy and safety of ginkgo terpene lactone preparations in the treatment of ischemic stroke: a systematic review and meta-analysis of randomized clinical trials","volume":"13","author":"Zhao","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.121703_bib192","doi-asserted-by":"crossref","first-page":"10453","DOI":"10.2147\/IJN.S272831","article-title":"Polymeric nanoparticles-based brain delivery with improved therapeutic efficacy of ginkgolide b in Parkinson'S disease","volume":"15","author":"Zhao","year":"2020","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.jep.2026.121703_bib193","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2021.771208","article-title":"Cardioprotective properties of ginkgo biloba extract 80 via the activation of AKT\/GSK3beta\/beta-catenin signaling pathway","volume":"8","author":"Zheng","year":"2021","journal-title":"Front. Mol. Biosci."},{"issue":"4","key":"10.1016\/j.jep.2026.121703_bib194","doi-asserted-by":"crossref","DOI":"10.1002\/jssc.70126","article-title":"Kaempferol molecularly imprinted monolithic columns prepared by a surface imprinting method and their applications to direct separation of flavonoids from ginkgo leaves by liquid chromatography","volume":"48","author":"Zhong","year":"2025","journal-title":"J. Sep. Sci."},{"issue":"5","key":"10.1016\/j.jep.2026.121703_bib195","article-title":"Mechanism of GBE combined with TP on the effect of AMPK\/SREBP-1c\/ACC pathway on lipid metabolism in heat-stressed broiler liver","volume":"12","author":"Zhou","year":"2025","journal-title":"Vet. Sci."},{"issue":"5","key":"10.1016\/j.jep.2026.121703_bib196","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.3390\/molecules23051029","article-title":"Multi-response optimization of ultrasonic assisted enzymatic extraction followed by macroporous resin purification for maximal recovery of flavonoids and ginkgolides from waste ginkgo biloba fallen leaves","volume":"23","author":"Zhou","year":"2018","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2026.121703_bib197","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/4598067","article-title":"Optimization of ultrasound-assisted extraction followed by macroporous resin purification for maximal recovery of functional components and removal of toxic components from ginkgo biloba leaves","volume":"2018","author":"Zhou","year":"2018","journal-title":"BioMed Res. Int."},{"issue":"12","key":"10.1016\/j.jep.2026.121703_bib198","doi-asserted-by":"crossref","first-page":"14778","DOI":"10.3390\/molecules171214778","article-title":"Purification and characterization of a novel \u223c18 kda antioxidant protein from ginkgo biloba seeds","volume":"17","author":"Zhou","year":"2012","journal-title":"Molecules"},{"issue":"10","key":"10.1016\/j.jep.2026.121703_bib199","first-page":"745","article-title":"Ginkgo biloba extract protects against depression-like behavior in mice through regulating gut microbial bile acid metabolism","volume":"21","author":"Zhou","year":"2023","journal-title":"Chin. J. Nat. Med."},{"issue":"1","key":"10.1016\/j.jep.2026.121703_bib200","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s11418-010-0456-z","article-title":"Ginkgo biloba extract enhances glucose tolerance in hyperinsulinism-induced hepatic cells","volume":"65","author":"Zhou","year":"2011","journal-title":"J. Nat. Med."},{"issue":"9","key":"10.1016\/j.jep.2026.121703_bib201","doi-asserted-by":"crossref","DOI":"10.1111\/cns.14914","article-title":"Investigating the effects of ginkgo biloba leaf extract on cognitive function in Alzheimer'S disease","volume":"30","author":"Zhu","year":"2024","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.jep.2026.121703_bib202","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1271321","article-title":"Potential targets and applications of nanodrug targeting myeloid cells in osteosarcoma for the enhancement of immunotherapy","volume":"14","author":"Zhu","year":"2023","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.121703_bib203","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.toxicon.2021.08.015","article-title":"In vivo toxicity assessment of 4'-o-methylpyridoxine from ginkgo biloba seeds: growth, hematology, metabolism, and oxidative parameters","volume":"201","author":"Zhu","year":"2021","journal-title":"Toxicon"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126005544?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126005544?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T09:58:36Z","timestamp":1778752716000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874126005544"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":188,"alternative-id":["S0378874126005544"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2026.121703","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Advanced extraction to targeted delivery: A holistic review of technological innovations and therapeutic mechanisms of Ginkgo biloba extract","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2026.121703","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"121703"}}