{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T11:46:44Z","timestamp":1785757604382,"version":"3.56.0"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100011710","name":"Shaanxi Provincial Science and Technology Department","doi-asserted-by":"publisher","award":["2023-JC-YB-783"],"award-info":[{"award-number":["2023-JC-YB-783"]}],"id":[{"id":"10.13039\/501100011710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.jep.2026.121766","type":"journal-article","created":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T15:40:45Z","timestamp":1777131645000},"page":"121766","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Elucidation of the mechanisms and therapeutic effects of Sini Decoction on anxiety induced by forced swimming stress in mice"],"prefix":"10.1016","volume":"368","author":[{"given":"Feiyan","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanbo","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiling","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Miao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinshang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuibing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3116-2921","authenticated-orcid":false,"given":"Xiaopeng","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2026.121766_bib1","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/978-981-32-9705-0_17","article-title":"Cognitive behavioral therapy, mindfulness-based cognitive therapy and acceptance commitment therapy for anxiety disorders: integrating traditional with digital treatment approaches","volume":"1191","author":"Apolin\u00e1rio-Hagen","year":"2020","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.jep.2026.121766_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jep.2014.12.023","article-title":"Characterizing the human equivalent dose of herbal medicines in animal toxicity studies","volume":"162","author":"Bae","year":"2015","journal-title":"J. Ethnopharmacol."},{"issue":"10","key":"10.1016\/j.jep.2026.121766_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics14102067","article-title":"Aconitum alkaloid songorine exerts potent gamma-aminobutyric Acid-A receptor agonist action in vivo and effectively decreases anxiety without adverse sedative or psychomotor effects in the rat","volume":"14","author":"Bali","year":"2022","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.jep.2026.121766_bib4","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/978-981-32-9705-0_20","article-title":"Role of benzodiazepines in anxiety disorders","volume":"1191","author":"Balon","year":"2020","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.jep.2026.121766_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.smrv.2021.101583","article-title":"Sleep and anxiety: from mechanisms to interventions","volume":"61","author":"Chellappa","year":"2022","journal-title":"Sleep Med. Rev."},{"issue":"12","key":"10.1016\/j.jep.2026.121766_bib6","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1248\/cpb.c22-00380","article-title":"Research progress on the mechanism of reducing toxicity and increasing the efficacy of sini decoction compatibility","volume":"70","author":"Chen","year":"2022","journal-title":"Chem. Pharm. Bull. (Tokyo)"},{"key":"10.1016\/j.jep.2026.121766_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.119692","article-title":"Evaluating the efficacy and safety of emodin, luteolin, and paeonol combination from Dahuang Mudan decoction in ameliorating ulcerative colitis","volume":"346","author":"Chen","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121766_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2024.103014","article-title":"Dynamic changes and future trend predictions of the global burden of anxiety disorders: analysis of 204 countries and regions from 1990 to 2021 and the impact of the COVID-19 pandemic","volume":"79","author":"Chen","year":"2025","journal-title":"EClinicalMedicine"},{"key":"10.1016\/j.jep.2026.121766_bib9","article-title":"Anxiety disorders","volume":"3","author":"Craske","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"issue":"4","key":"10.1016\/j.jep.2026.121766_bib10","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.cell.2019.10.001","article-title":"Stress-induced metabolic disorder in peripheral CD4(+) T cells leads to anxiety-like behavior","volume":"179","author":"Fan","year":"2019","journal-title":"Cell"},{"issue":"7","key":"10.1016\/j.jep.2026.121766_bib11","doi-asserted-by":"crossref","first-page":"13384","DOI":"10.3390\/molecules200713384","article-title":"Molecular docking and structure-based drug design strategies","volume":"20","author":"Ferreira","year":"2015","journal-title":"Molecules"},{"issue":"7","key":"10.1016\/j.jep.2026.121766_bib12","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.biopsych.2018.02.003","article-title":"Distinct proteomic, transcriptomic, and epigenetic stress responses in dorsal and ventral hippocampus","volume":"84","author":"Floriou-Servou","year":"2018","journal-title":"Biol. Psychiatry"},{"issue":"7","key":"10.1016\/j.jep.2026.121766_bib13","doi-asserted-by":"crossref","DOI":"10.3390\/molecules28073157","article-title":"Targeting mTOR for anti-aging and anti-cancer therapy","volume":"28","author":"Fu","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2026.121766_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115270","article-title":"Aconitine: a review of its pharmacokinetics, pharmacology, toxicology and detoxification","volume":"293","author":"Gao","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121766_bib15","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3389\/fnbeh.2020.00061","article-title":"The impact of the PI3K\/Akt signaling pathway in anxiety and working memory in young and middle-aged PDK1 K465E Knock-In mice","volume":"14","author":"Gim\u00e9nez-Llort","year":"2020","journal-title":"Front. Behav. Neurosci."},{"issue":"2","key":"10.1016\/j.jep.2026.121766_bib16","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1142\/S0192415X0900693X","article-title":"Sini tang prevents depression-like behavior in rats exposed to chronic unpredictable stress","volume":"37","author":"Guo","year":"2009","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.jep.2026.121766_bib17","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2025.1597131","article-title":"PTEN in somatostatin neurons regulates fear and anxiety and is required for inhibitory synaptic connectivity within central amygdala","volume":"19","author":"Holford","year":"2025","journal-title":"Front. Cell. Neurosci."},{"issue":"1","key":"10.1016\/j.jep.2026.121766_bib18","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s13045-021-01137-8","article-title":"Targeting Akt in cancer for precision therapy","volume":"14","author":"Hua","year":"2021","journal-title":"J. Hematol. Oncol."},{"issue":"3","key":"10.1016\/j.jep.2026.121766_bib19","first-page":"479","article-title":"Integration strategy of network pharmacology in traditional Chinese medicine: a narrative review","volume":"42","author":"Jiashuo","year":"2022","journal-title":"J. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2026.121766_bib20","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/978-981-32-9705-0_9","article-title":"The role of early life stress in HPA axis and anxiety","volume":"1191","author":"Juruena","year":"2020","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.jep.2026.121766_bib21","series-title":"ELEVATED PLUS MAZE","article-title":"The effects of open field exposure on the anxiety and locomotive behavior of adult male wistar rats","author":"Kumar","year":"2016"},{"issue":"1","key":"10.1016\/j.jep.2026.121766_bib22","doi-asserted-by":"crossref","first-page":"4395","DOI":"10.1038\/s41598-019-40698-0","article-title":"The impact of early life stress on anxiety symptoms in late adulthood","volume":"9","author":"L\u00e4hdepuro","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2026.121766_bib23","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.physbeh.2016.02.014","article-title":"Assessment of anxiety in open field and elevated plus maze using infrared thermography","volume":"157","author":"Lecorps","year":"2016","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.jep.2026.121766_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.116222","article-title":"Early-life exposure to PM2.5 leads to ASD-like phenotype in male offspring rats through activation of PI3K-AKT signaling pathway","volume":"274","author":"Li","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"2","key":"10.1016\/j.jep.2026.121766_bib25","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s40264-014-0250-z","article-title":"Safety surveillance of traditional Chinese medicine: current and future","volume":"38","author":"Liu","year":"2015","journal-title":"Drug Saf."},{"issue":"5","key":"10.1016\/j.jep.2026.121766_bib26","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1038\/s41386-022-01515-x","article-title":"Medial prefrontal cortex input to basolateral amygdala controls acute stress-induced short-term anxiety-like behavior in mice","volume":"48","author":"Liu","year":"2023","journal-title":"Neuropsychopharmacology"},{"issue":"9","key":"10.1016\/j.jep.2026.121766_bib27","doi-asserted-by":"crossref","first-page":"4149","DOI":"10.1002\/ptr.7876","article-title":"11-Ethoxyviburtinal improves chronic restraint stress-induced anxiety-like behaviors in gender-specific mice via PI3K\/Akt and E(2)\/ER\u03b2 signaling pathways","volume":"37","author":"Lyu","year":"2023","journal-title":"Phytother Res."},{"key":"10.1016\/j.jep.2026.121766_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.118013","article-title":"Glycyrrhizic acid treatment ameliorates anxiety-like behaviour via GLT1 and Per1\/2-dependent pathways","volume":"328","author":"Ma","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121766_bib29","doi-asserted-by":"crossref","first-page":"131","DOI":"10.3389\/fnbeh.2019.00131","article-title":"Loss of glutamate decarboxylase 67 in somatostatin-expressing neurons leads to anxiety-like behavior and alteration in the Akt\/GSK3\u03b2 signaling pathway","volume":"13","author":"Miyata","year":"2019","journal-title":"Front. Behav. Neurosci."},{"issue":"8","key":"10.1016\/j.jep.2026.121766_bib30","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1002\/ddr.21461","article-title":"Dose translation between laboratory animals and human in preclinical and clinical phases of drug development","volume":"79","author":"Nair","year":"2018","journal-title":"Drug Dev. Res."},{"key":"10.1016\/j.jep.2026.121766_bib31","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/978-981-32-9705-0_12","article-title":"Anxiety disorders in the DSM-5: changes, controversies, and future directions","volume":"1191","author":"Park","year":"2020","journal-title":"Adv. Exp. Med. Biol."},{"issue":"Pt 4","key":"10.1016\/j.jep.2026.121766_bib32","article-title":"Deletion of p75NTR rescues behavioral and cognitive dysfunction in SPS-induced PTSD mice through hippocampal PI3K\/Akt\/mTOR pathway","volume":"308","author":"Peng","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jep.2026.121766_bib33","article-title":"Acute and subacute oral toxicity assessment of Gancao Xiexin decoction in Sprague-Dawley rats","volume":"13","author":"Ru","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"3","key":"10.1016\/j.jep.2026.121766_bib34","doi-asserted-by":"crossref","DOI":"10.1111\/gbb.12423","article-title":"Epigenetics at the crossroads between genes, environment and resilience in anxiety disorders","volume":"17","author":"Schiele","year":"2018","journal-title":"Gene Brain Behav."},{"key":"10.1016\/j.jep.2026.121766_bib35","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.nutres.2024.01.014","article-title":"Ginger alleviates mechanical hypersensitivity and anxio-depressive behavior in rats with diabetic neuropathy through beneficial actions on gut microbiome composition, mitochondria, and neuroimmune cells of colon and spinal cord","volume":"124","author":"Shen","year":"2024","journal-title":"Nutr. Res."},{"issue":"1","key":"10.1016\/j.jep.2026.121766_bib36","first-page":"88","article-title":"[Effect of Jiawei Sini Decoction on HPA function of rats with restraint psychological stress]","volume":"31","author":"Shi","year":"2008","journal-title":"Zhong Yao Cai"},{"key":"10.1016\/j.jep.2026.121766_bib37","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2022.866764","article-title":"Current advances in CETSA","volume":"9","author":"Tolvanen","year":"2022","journal-title":"Front. Mol. Biosci."},{"issue":"23","key":"10.1016\/j.jep.2026.121766_bib38","first-page":"1863","article-title":"[The effect of four kinds of traditional Chinese herbal compound on the experimental acute stress behaviors and the hypothalamus-pituitary-adrenal gland axis]","volume":"30","author":"Tong","year":"2005","journal-title":"Zhongguo Zhongyao Zazhi"},{"key":"10.1016\/j.jep.2026.121766_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2019.109812","article-title":"Adolescent forced swim stress increases social anxiety-like behaviors and alters kappa opioid receptor function in the basolateral amygdala of male rats","volume":"98","author":"Varlinskaya","year":"2020","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"3","key":"10.1016\/j.jep.2026.121766_bib40","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1080\/13651501.2021.1941120","article-title":"Subsyndromal generalised anxiety disorder: operationalisation and epidemiology - a systematic literature survey","volume":"26","author":"Volz","year":"2022","journal-title":"Int. J. Psychiatr. Clin. Pract."},{"issue":"1","key":"10.1016\/j.jep.2026.121766_bib41","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1038\/s41467-022-29367-5","article-title":"Multiomic profiling of the acute stress response in the mouse hippocampus","volume":"13","author":"von Ziegler","year":"2022","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.jep.2026.121766_bib42","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1248\/bpb.b21-00324","article-title":"Application of reverse docking in the research of small molecule drugs and traditional Chinese medicine","volume":"45","author":"Wang","year":"2022","journal-title":"Biol. Pharm. Bull."},{"issue":"10","key":"10.1016\/j.jep.2026.121766_bib43","doi-asserted-by":"crossref","DOI":"10.3390\/vetsci10100615","article-title":"Acute and 28-Day repeated-dose oral toxicity of the herbal formula Guixiong Yimu San in mice and sprague-dawley rats","volume":"10","author":"Wang","year":"2023","journal-title":"Vet. Sci."},{"issue":"11","key":"10.1016\/j.jep.2026.121766_bib44","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s11920-021-01290-4","article-title":"Correlates of quality of life in anxiety disorders: review of recent research","volume":"23","author":"Wilmer","year":"2021","journal-title":"Curr. Psychiatry Rep."},{"issue":"1","key":"10.1016\/j.jep.2026.121766_bib45","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/s13578-020-00416-0","article-title":"Roles of the PI3K\/AKT\/mTOR signalling pathways in neurodegenerative diseases and tumours","volume":"10","author":"Xu","year":"2020","journal-title":"Cell Biosci."},{"key":"10.1016\/j.jep.2026.121766_bib46","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.bbr.2019.01.008","article-title":"PI3K\/Akt\/NF-\u03baB signaling pathway regulates behaviors in adolescent female rats following with neonatal maternal deprivation and chronic mild stress","volume":"362","author":"Ye","year":"2019","journal-title":"Behav. Brain Res."},{"issue":"5","key":"10.1016\/j.jep.2026.121766_bib47","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1002\/ptr.6033","article-title":"Herbal medicine for depression and anxiety: a systematic review with assessment of potential psycho-oncologic relevance","volume":"32","author":"Yeung","year":"2018","journal-title":"Phytother Res."},{"issue":"3","key":"10.1016\/j.jep.2026.121766_bib48","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1007\/s13311-020-00857-y","article-title":"Activation of LXR\u03b2 signaling in the Amygdala confers anxiolytic effects through rebalancing excitatory and inhibitory neurotransmission upon acute stress","volume":"17","author":"Yu","year":"2020","journal-title":"Neurotherapeutics"},{"issue":"1","key":"10.1016\/j.jep.2026.121766_bib49","doi-asserted-by":"crossref","DOI":"10.1093\/bib\/bbad518","article-title":"Network pharmacology: towards the artificial intelligence-based precision traditional Chinese medicine","volume":"25","author":"Zhang","year":"2023","journal-title":"Briefings Bioinf."},{"key":"10.1016\/j.jep.2026.121766_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2022.106204","article-title":"Medicinal herbs for the treatment of anxiety: a systematic review and network meta-analysis","volume":"179","author":"Zhang","year":"2022","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.jep.2026.121766_bib51","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.neuroscience.2022.09.003","article-title":"Increased anxiety-like behaviors in Adgra1(-\/-) Male but not female mice are attributable to Elevated Neuron Dendrite density, upregulated PSD95 expression, and abnormal activation of the PI3K\/AKT\/GSK-3\u03b2 and MEK\/ERK pathways","volume":"503","author":"Zhang","year":"2022","journal-title":"Neuroscience"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126006185?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126006185?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T11:06:30Z","timestamp":1785755190000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874126006185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":51,"alternative-id":["S0378874126006185"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2026.121766","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Elucidation of the mechanisms and therapeutic effects of Sini Decoction on anxiety induced by forced swimming stress in mice","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2026.121766","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"121766"}}