{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T01:36:21Z","timestamp":1790213781235,"version":"4.1.0"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","award":["RS-2025-25442355"],"award-info":[{"award-number":["RS-2025-25442355"]}],"id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["RS- 2022-NR069341"],"award-info":[{"award-number":["RS- 2022-NR069341"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["RS-2022-NR070587"],"award-info":[{"award-number":["RS-2022-NR070587"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["RS-2022-KH130309"],"award-info":[{"award-number":["RS-2022-KH130309"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["RS-2024-00407544"],"award-info":[{"award-number":["RS-2024-00407544"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["RS-2025-24534393"],"award-info":[{"award-number":["RS-2025-24534393"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["RS-2023-00217595"],"award-info":[{"award-number":["RS-2023-00217595"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["RS-2026-25485875"],"award-info":[{"award-number":["RS-2026-25485875"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.jep.2026.121903","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T16:13:22Z","timestamp":1779812002000},"page":"121903","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Melampodium divaricatum (Rich.) DC. extracts exert anti-inflammatory effects via inhibition of the NLRP3 inflammasome"],"prefix":"10.1016","volume":"369","author":[{"given":"Seongjong","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seoyeon","family":"Jang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ja-Gyeong","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaehyeok","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Indiana M.","family":"Coronado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyung Won","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Hee","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Keun","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo-Yong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sangho","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyungseok","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man S.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Hyub","family":"Paik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jongmin","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoonsung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3240-8938","authenticated-orcid":false,"given":"Yong Hwan","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2026.121903_bib1","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.677994","article-title":"Molecular insights into neutrophil biology from the zebrafish perspective: lessons from CD18 deficiency","volume":"12","author":"Bader","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jep.2026.121903_bib2","doi-asserted-by":"crossref","first-page":"8979","DOI":"10.3390\/ijms23168979","article-title":"Targeting NLRP3-mediated neuroinflammation in Alzheimer's disease treatment","volume":"23","author":"Barczuk","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2026.121903_bib3","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1746-4269-3-18","article-title":"Plants used traditionally to treat malaria in Brazil: the archives of Flora Medicinal","volume":"3","author":"Botsaris","year":"2007","journal-title":"J. Ethnobiol. Ethnomed."},{"key":"10.1016\/j.jep.2026.121903_bib4","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.tips.2025.04.007","article-title":"Targeting the NLRP3 inflammasome for inflammatory disease therapy","volume":"46","author":"Cabral","year":"2025","journal-title":"Trends in pharmacological sciences"},{"key":"10.1016\/j.jep.2026.121903_bib5","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0378-8741(96)01424-9","article-title":"Screening of medicinal plants used by the Garifuna of Eastern Nicaragua for bioactive compounds","volume":"53","author":"Coe","year":"1996","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121903_bib6","first-page":"101","article-title":"Bioactivity of 68 Species of medicinal plants of Eastern Nicaragua","volume":"9","author":"Coe","year":"2020","journal-title":"J. Pharmacogn. Phytochem."},{"key":"10.1016\/j.jep.2026.121903_bib7","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1038\/s41589-019-0277-7","article-title":"MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition","volume":"15","author":"Coll","year":"2019","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.jep.2026.121903_bib8","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1186\/s12935-022-02721-9","article-title":"Sesquiterpenoid lactones as potential anti-cancer agents: an update on molecular mechanisms and recent studies","volume":"22","author":"Dhyani","year":"2022","journal-title":"Cancer Cell Int."},{"key":"10.1016\/j.jep.2026.121903_bib9","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1002\/cbdv.201300322","article-title":"Composition and activity against oral pathogens of the essential oil of Melampodium divaricatum (Rich.) DC","volume":"11","author":"Duarte Moreira","year":"2014","journal-title":"Chem. Biodivers."},{"key":"10.1016\/j.jep.2026.121903_bib10","first-page":"e49","article-title":"mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish","volume":"117","author":"Ellett","year":"2011","journal-title":"Blood, The Journal of the American Society of Hematology"},{"key":"10.1016\/j.jep.2026.121903_bib12","doi-asserted-by":"crossref","first-page":"407","DOI":"10.2147\/JIR.S140188","article-title":"Mechanisms of NF-\u03baB p65 and strategies for therapeutic manipulation","author":"Giridharan","year":"2018","journal-title":"J. Inflamm. Res."},{"key":"10.1016\/j.jep.2026.121903_bib13","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.immuni.2016.08.010","article-title":"K+ efflux-independent NLRP3 inflammasome activation by small molecules targeting mitochondria","volume":"45","author":"Gro\u00df","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.jep.2026.121903_bib14","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1189\/jlb.4MR1114-524R","article-title":"Neutrophils in host defense: new insights from zebrafish","volume":"98","author":"Harvie","year":"2015","journal-title":"Journal of Leucocyte Biology"},{"key":"10.1016\/j.jep.2026.121903_bib15","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.vascn.2012.10.003","article-title":"A zebrafish phenotypic assay for assessing drug-induced hepatotoxicity","volume":"67","author":"He","year":"2013","journal-title":"J. Pharmacol. Toxicol. Methods"},{"key":"10.1016\/j.jep.2026.121903_bib16","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1038\/nature07725","article-title":"AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC","volume":"458","author":"Hornung","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.jep.2026.121903_bib17","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.redox.2017.04.020","article-title":"Mitochondrial ROS induced by chronic ethanol exposure promote hyper-activation of the NLRP3 inflammasome","volume":"12","author":"Hoyt","year":"2017","journal-title":"Redox Biol."},{"key":"10.1016\/j.jep.2026.121903_bib18","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/S0031-9422(98)00700-6","article-title":"Acylated 2-hydroxythymol 3-O-diglycosides from Melampodium divaricatum","volume":"51","author":"H\u00fether","year":"1999","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jep.2026.121903_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2022.105386","article-title":"Glycyrrhiza uralensis polysaccharides ameliorate acute lung injury by inhibiting the activation of multiple inflammasomes","volume":"100","author":"Kan","year":"2023","journal-title":"J. Funct.Foods"},{"key":"10.1016\/j.jep.2026.121903_bib20","first-page":"132","article-title":"Origins and unconventional behavior of neutrophils in developing zebrafish","volume":"111","author":"Le Guyader","year":"2008","journal-title":"Blood, The Journal of the American Society of Hematology"},{"key":"10.1016\/j.jep.2026.121903_bib21","doi-asserted-by":"crossref","first-page":"194","DOI":"10.2337\/db12-0420","article-title":"Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes","volume":"62","author":"Lee","year":"2013","journal-title":"Diabetes"},{"key":"10.1016\/j.jep.2026.121903_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.117711","article-title":"Guarea microcarpa C. DC. extract inhibits NLRP3 inflammasome by suppressing its ATPase activity","volume":"323","author":"Lee","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121903_bib23","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1016\/S0021-9258(17)49920-0","article-title":"The zebrafish NLRP3 inflammasome has functional roles in ASC-dependent interleukin-1\u03b2 maturation and gasdermin E\u2013mediated pyroptosis","volume":"295","author":"Li","year":"2020","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jep.2026.121903_bib24","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202153499","article-title":"Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7\u2010NLRP3 interaction","volume":"23","author":"Li","year":"2022","journal-title":"EMBO Rep."},{"key":"10.1016\/j.jep.2026.121903_bib25","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1073\/pnas.1417945112","article-title":"Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5","volume":"112","author":"Matusiak","year":"2015","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.jep.2026.121903_bib26","article-title":"Antileishmanial activity of Melampodium divaricatum and Casearia sylvestris essential oils on Leishmania amazonensis","volume":"61","author":"Moreira","year":"2019","journal-title":"Rev. do Inst. Med. Trop. S\u00e3o Paulo"},{"key":"10.1016\/j.jep.2026.121903_bib27","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/j.immuni.2013.05.016","article-title":"K+ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter","volume":"38","author":"Mu\u00f3OZ-Planillo","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.jep.2026.121903_bib28","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.820541","article-title":"Canagliflozin ameliorates NLRP3 inflammasome-mediated inflammation through inhibiting NF-\u03baB signaling and upregulating Bif-1","volume":"13","author":"Niu","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.121903_bib29","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.tiv.2005.08.012","article-title":"Investigation of genotoxic and antigenotoxic activities of Melampodium divaricatum in Salmonella typhimurium","volume":"20","author":"Nogueira","year":"2006","journal-title":"Toxicol. Vitro"},{"key":"10.1016\/j.jep.2026.121903_bib30","doi-asserted-by":"crossref","DOI":"10.1002\/cbdv.202100369","article-title":"Antinociceptive activity of compounds from the aqueous extract of Melampodium divaricatum","volume":"18","author":"P\u00ebREZ\u2010V\u00e3SQUEZ","year":"2021","journal-title":"Chem. Biodivers."},{"key":"10.1016\/j.jep.2026.121903_bib31","doi-asserted-by":"crossref","first-page":"3295","DOI":"10.1002\/ptr.7514","article-title":"Polysaccharide extract from Isatidis Radix inhibits multiple inflammasomes activation and alleviate gouty arthritis","volume":"36","author":"Ren","year":"2022","journal-title":"Phytother Res."},{"key":"10.1016\/j.jep.2026.121903_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155758","article-title":"Tryptanthrin suppresses multiple inflammasome activation to regulate NASH progression by targeting ASC protein","volume":"131","author":"Ren","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2026.121903_bib33","doi-asserted-by":"crossref","first-page":"2758","DOI":"10.1002\/eji.201545958","article-title":"Potassium efflux fires the canon: potassium efflux as a common trigger for canonical and noncanonical NLRP3 pathways","volume":"45","author":"Rivers\u2010Auty","year":"2015","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.jep.2026.121903_bib34","doi-asserted-by":"crossref","first-page":"73","DOI":"10.31958\/js.v13i2.4672","article-title":"Potential of medicinal plants in the Asteraceae family found in harau Lima Puluh Kota Regency","volume":"13","author":"Rizki","year":"2021","journal-title":"Sainstek: Jurnal Sains dan Teknologi"},{"key":"10.1016\/j.jep.2026.121903_bib35","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1038\/cdd.2013.37","article-title":"AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC","volume":"20","author":"Sagulenko","year":"2013","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.jep.2026.121903_bib36","series-title":"Melampodium divaricatum (Butter Daisy). Encyclopedia of Plant Viruses and Viroids","author":"Sastry","year":"2020"},{"key":"10.1016\/j.jep.2026.121903_bib37","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1038\/nature15514","article-title":"Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death","volume":"526","author":"Shi","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.jep.2026.121903_bib38","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1111\/j.1365-2249.2009.03893.x","article-title":"Innate immunity and inflammation\u2013two facets of the same anti-infectious reaction","volume":"156","author":"Si-Tahar","year":"2009","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.jep.2026.121903_bib39","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/978-1-62703-523-1_8","article-title":"ASC speck formation as a readout for inflammasome activation","volume":"1040","author":"Stutz","year":"2013","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.jep.2026.121903_bib40","doi-asserted-by":"crossref","first-page":"S24","DOI":"10.1016\/j.jaci.2009.07.016","article-title":"Innate immunity","volume":"125","author":"Turvey","year":"2010","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.jep.2026.121903_bib41","doi-asserted-by":"crossref","first-page":"159807","DOI":"10.1155\/2012\/159807","article-title":"Pathogen recognition and activation of the innate immune response in zebrafish","volume":"2012","author":"VAN Der Vaart","year":"2012","journal-title":"Advances in hematology"},{"key":"10.1016\/j.jep.2026.121903_bib42","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nm.2279","article-title":"The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance","volume":"17","author":"Vandanmagsar","year":"2011","journal-title":"Nat. Med."},{"key":"10.1016\/j.jep.2026.121903_bib43","article-title":"Zebrafish as a vertebrate model for high-throughput drug toxicity screening: mechanisms, novel techniques, and future perspectives","author":"Wang","year":"2025","journal-title":"J. Pharm. Anal."},{"key":"10.1016\/j.jep.2026.121903_bib44","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2020.620984","article-title":"Modeling inflammation in zebrafish for the development of anti-inflammatory drugs","volume":"8","author":"Xie","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.jep.2026.121903_bib45","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.609441","article-title":"Distinct molecular mechanisms underlying potassium efflux for NLRP3 inflammasome activation","volume":"11","author":"Xu","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jep.2026.121903_bib46","article-title":"Anti\u2010inflammatory effect of Trichospira verticillata via suppression of the NLRP3 inflammasome in neutrophilic asthma","volume":"28","author":"Yang","year":"2024","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.jep.2026.121903_bib47","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1089\/ars.2014.5868","article-title":"Reactive oxygen species-induced TXNIP drives fructose-mediated hepatic inflammation and lipid accumulation through NLRP3 inflammasome activation","volume":"22","author":"Zhang","year":"2015","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.jep.2026.121903_bib48","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1038\/nature10510","article-title":"The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus","volume":"477","author":"Zhao","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.jep.2026.121903_bib49","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/nature09663","article-title":"A role for mitochondria in NLRP3 inflammasome activation","volume":"469","author":"Zhou","year":"2011","journal-title":"Nature"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126007555?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126007555?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T21:17:32Z","timestamp":1783113452000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874126007555"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":48,"alternative-id":["S0378874126007555"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2026.121903","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Melampodium divaricatum (Rich.) DC. extracts exert anti-inflammatory effects via inhibition of the NLRP3 inflammasome","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2026.121903","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"121903"}}