{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T23:02:55Z","timestamp":1793746975235,"version":"4.6.1"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100008132","name":"Universidade Federal de Pernambuco","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008132","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["140438\/2022-0"],"award-info":[{"award-number":["140438\/2022-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.jep.2026.121947","type":"journal-article","created":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T15:31:13Z","timestamp":1780155073000},"page":"121947","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Gastroprotective action of Piper aduncum L. leaf essential oil mediated by \u03b12-adrenergic biochemical pathways, nitric oxide synthase, and sulfhydryl compounds"],"prefix":"10.1016","volume":"370","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8670-6842","authenticated-orcid":false,"given":"Paulo Henrique","family":"Eloi Fernandes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suyane","family":"de Deus e Melo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Henrique","family":"Andrade do Nascimento Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna","family":"de Sousa Gomes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz Meyruze","family":"Barros da Fons\u00eaca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"La\u00eds Ruanita","family":"Leopoldina Galv\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paloma","family":"Maria da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luzia","family":"Ab\u00edlio da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno Vinicius","family":"Souza da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00falio C\u00e9sar","family":"Ribeiro de Oliveira Farias de Aguiar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Maria do Amaral Ferraz Navarro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendeo Kennedy","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Tereza dos Santos Correia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcia","family":"Vanusa da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2026.121947_bib1","series-title":"Identification of Essential Oil Components by Gas Chromatography\/Quadrupole Mass Spectroscopy","author":"Adams","year":"2007"},{"key":"10.1016\/j.jep.2026.121947_bib2","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.sajb.2024.09.016","article-title":"Essential oils cause membrane disruption and autoaggregation of MDR Acinetobacter baumannii cells","volume":"174","author":"Aleksic Sabo","year":"2024","journal-title":"South Afr. J. Bot."},{"issue":"12","key":"10.1016\/j.jep.2026.121947_bib3","doi-asserted-by":"crossref","first-page":"7535","DOI":"10.1007\/s10787-025-02021-4","article-title":"Myricetin alleviates indomethacin-induced gastric ulcers in rats via antioxidant, anti-inflammatory and antiapoptotic mechanisms","volume":"33","author":"Ansari","year":"2025","journal-title":"Inflammopharmacology"},{"issue":"4","key":"10.1016\/j.jep.2026.121947_bib4","first-page":"608","article-title":"Efecto gastroprotector y antisecretor de un fitof\u00e1rmaco de hojas de matico (Piper aduncum) [Gastroprotective and antisecretory effect of a phytochemical made from matico leaves (Piper aduncum)]","volume":"30","author":"Arroyo","year":"2013","journal-title":"Rev. Peru. Med. Exp. Salud Publica"},{"key":"10.1016\/j.jep.2026.121947_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.indcrop.2023.117216","article-title":"Effects of postharvest UV-C irradiation on essential oils from leaves of Piper aduncum L. for industrial and medicinal use","volume":"203","author":"Assun\u00e7\u00e3o","year":"2023","journal-title":"Ind. Crops Prod."},{"key":"10.1016\/j.jep.2026.121947_bib6","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.jep.2015.03.021","article-title":"Helicteres sacarolha A. St- Hil. et al.: Gastroprotective and possible mechanism of actions in experimental animals","volume":"166","author":"Balogun","year":"2015","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121947_bib7","article-title":"Gastroprotective effect of ethyl acetate extract from Avicennia schaueriana Stapf & Leechman and underlying mechanisms","volume":"112","author":"Barbosa","year":"2019","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2026.121947_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114792","article-title":"Gastroprotective action of the ethanol extract of Leonurus sibiricus L. (Lamiaceae) in mice","volume":"284","author":"Biano","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121947_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.113623","article-title":"The gastroprotective effect of red propolis extract from Northeastern Brazil and the role of its isolated compounds","volume":"267","author":"Boeing","year":"2021","journal-title":"J. Ethnopharmacol."},{"issue":"7","key":"10.1016\/j.jep.2026.121947_bib10","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1007\/s10646-019-02072-8","article-title":"Cytotoxicity of Piper aduncum (Piperaceae) essential oil in brown stink bug Euschistus heros (Heteroptera: pentatomidae)","volume":"28","author":"Cossolin","year":"2019","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.jep.2026.121947_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcab.2024.103403","article-title":"Antioxidant activity evaluation of the combination of oregano (Origanum vulgare) and laurel (Laurus nobilis) essential oil as two natural \u201cchain-breaking\u201d antioxidants by direct measurement of sunflower oil oxidation","volume":"61","author":"Cravero","year":"2024","journal-title":"Biocatal. Agric. Biotechnol."},{"issue":"2","key":"10.1016\/j.jep.2026.121947_bib12","doi-asserted-by":"crossref","first-page":"3035","DOI":"10.1007\/s00210-025-04597-8","article-title":"Uncovering the gastroprotective properties of Araucaria brown propolis and its active compound, abietic acid","volume":"399","author":"Cury","year":"2026","journal-title":"Naunyn-Schmiedebergs Arch Pharmacol"},{"key":"10.1016\/j.jep.2026.121947_bib13","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jep.2016.07.011","article-title":"Piper umbellatum L.: a medicinal plant with gastric-ulcer protective and ulcer healing effects in experimental rodent models","volume":"192","author":"da Silva Junior","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121947_bib14","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.fitote.2014.05.009","article-title":"Antileishmanial activity evaluation of adunchalcone, a new prenylated dihydrochalcone from Piper aduncum L","volume":"97","author":"Dal Picolo","year":"2014","journal-title":"Fitoterapia"},{"issue":"6","key":"10.1016\/j.jep.2026.121947_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.sjbs.2022.103284","article-title":"Therapeutic strategies of Moringa oleifera Lam. (Moringaceae) for stomach and forestomach ulceration induced by HCl\/EtOH in rat model","volume":"29","author":"Dalhoumi","year":"2022","journal-title":"Saudi J. Biol. Sci."},{"key":"10.1016\/j.jep.2026.121947_bib16","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.cbi.2016.11.020","article-title":"Gastroprotective and ulcer healing effects of hydroethanolic extract of leaves of Caryocar coriaceum: mechanisms involved in the gastroprotective activity","volume":"261","author":"De Lacerda Neto","year":"2017","journal-title":"Chem. Biol. Interact."},{"issue":"6","key":"10.1016\/j.jep.2026.121947_bib17","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1007\/s43450-024-00577-w","article-title":"Gastroprotective and ulcer healing effects of Lonchocarpus sericeus seed extract in rodents","volume":"34","author":"De Paula Freire","year":"2024","journal-title":"Rev. Bras. Farmacogn."},{"key":"10.1016\/j.jep.2026.121947_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2021.112482","article-title":"Tannic acid is a gastroprotective that regulates inflammation and oxidative stress","volume":"156","author":"De Veras","year":"2021","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jep.2026.121947_bib19","article-title":"Inhibition of Vibrio parahaemolyticus biofilm formation in squid (Loligo duvauceli) meat by Cymbopogon citratus essential oil and DNase: an investigative study","volume":"3","author":"Dinakarkumar","year":"2024","journal-title":"Food Human."},{"key":"10.1016\/j.jep.2026.121947_bib20","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.mrgentox.2014.07.008","article-title":"Insecticidal and genotoxic potential of two semi-synthetic derivatives of dillapiole for the control of Aedes (Stegomyia) aegypti (Diptera: culicidae)","volume":"772","author":"Domingos","year":"2014","journal-title":"Mutat. Res. Genet. Toxicol. Environ. Mutagen"},{"key":"10.1016\/j.jep.2026.121947_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2022.739127","article-title":"Efficacy of the essential oils of Aloysia triphylla, Lippia gracilis and Piper aduncum in the control of Piscinoodinium pillulare (Shaperclaus, 1954) in Colossoma macropomum (Cuvier, 1818)","volume":"565","author":"dos Santos","year":"2023","journal-title":"Aquaculture"},{"key":"10.1016\/j.jep.2026.121947_bib22","article-title":"Development of a gastroprotector from Algrizea minor essential oil complexed with \u03b2-Cyclodextrin","volume":"94","author":"Fernandes","year":"2024","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"10.1016\/j.jep.2026.121947_bib23","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.biochi.2013.12.008","article-title":"Cytotoxic effects of dillapiole on MDA-MB-231 cells involve the induction of apoptosis through the mitochondrial pathway by inducing an oxidative stress while altering the cytoskeleton network","volume":"99","author":"Ferreira","year":"2014","journal-title":"Biochimie"},{"key":"10.1016\/j.jep.2026.121947_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116338","article-title":"Evaluation of the gastroprotective and ulcer healing properties by Fridericia chica (Bonpl.) L.G. Lohmann hydroethanolic extract of leaves","volume":"309","author":"Figueiredo","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121947_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.113744","article-title":"Cashew apple byproduct: gastroprotective effects of standardized extract","volume":"269","author":"Goulart da Silva","year":"2021","journal-title":"J. Ethnopharmacol."},{"issue":"4","key":"10.1016\/j.jep.2026.121947_bib26","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/sj.bjp.0700941","article-title":"Protection by amylin of gastric erosions induced by indomethacin or ethanol in rats","volume":"120","author":"Guidobono","year":"1997","journal-title":"Br. J. Pharmacol."},{"issue":"6","key":"10.1016\/j.jep.2026.121947_bib27","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/S0254-6272(15)30157-6","article-title":"Gastroprotective effect of aqueous stem bark extract of Ziziphus jujuba L. against HCl\/Ethanol-induced gastric mucosal injury in rats","volume":"35","author":"Hamedi","year":"2015","journal-title":"J. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2026.121947_bib28","article-title":"Acute toxicity profile and gastroprotective potential of ethanolic leaf extract of Manihot esculenta Crantz","volume":"17","author":"Henneh","year":"2022","journal-title":"Sci. Afr."},{"key":"10.1016\/j.jep.2026.121947_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.drup.2024.101100","article-title":"Lansoprazole (LPZ) reverses multidrug resistance (MDR) in cancer through impeding ATP-binding cassette (ABC) transporter-mediated chemotherapeutic drug efflux and lysosomal sequestration","volume":"76","author":"Ji","year":"2024","journal-title":"Drug Resist. Updates"},{"key":"10.1016\/j.jep.2026.121947_bib30","article-title":"Peptic ulcer disease","author":"Malik","year":"2026","journal-title":"StatPearls"},{"issue":"5","key":"10.1016\/j.jep.2026.121947_bib31","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1590\/S0102-695X2013000500005","article-title":"Growth study and essential oil analysis of Piper aduncum from two sites of Cerrado biome of Minas Gerais state, Brazil","volume":"23","author":"Oliveira","year":"2013","journal-title":"Rev. Bras. Farmacogn."},{"issue":"3","key":"10.1016\/j.jep.2026.121947_bib32","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.bjp.2014.07.004","article-title":"Chemical composition and efficacy in the egg-hatching inhibition of essential oil of Piper aduncum against Haemonchus contortus from sheep","volume":"24","author":"Oliveira","year":"2014","journal-title":"Rev. Bras. Farmacogn."},{"key":"10.1016\/j.jep.2026.121947_bib33","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.indcrop.2016.03.016","article-title":"Essential oil of monkey-pepper (Piper aduncum L.) cultivated under different light environments","volume":"85","author":"Pacheco","year":"2016","journal-title":"Ind. Crops Prod."},{"issue":"12","key":"10.1016\/j.jep.2026.121947_bib34","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1002\/ardp.201200212","article-title":"Dillapiole as antileishmanial agent: discovery, cytotoxic activity and preliminary SAR studies of dillapiole analogues","volume":"345","author":"Parise-Filho","year":"2012","journal-title":"Arch. Pharm."},{"issue":"11","key":"10.1016\/j.jep.2026.121947_bib35","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.3109\/13880209.2011.575793","article-title":"The anti-inflammatory activity of dillapiole and some semisynthetic analogues","volume":"49","author":"Parise-Filho","year":"2011","journal-title":"Pharm. Biol."},{"issue":"6","key":"10.1016\/j.jep.2026.121947_bib36","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1007\/s10787-022-00982-4","article-title":"Gastroprotective activities of Peperomia pellucida L. and Pachyrhizus erosus L. extracts combination on ethanol-induced rats","volume":"30","author":"Pertiwi","year":"2022","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.jep.2026.121947_bib37","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.bse.2011.12.025","article-title":"Chemical characterization of essential oil constituents of four populations of Piper aduncum L. from Distrito Federal, Brazil","volume":"42","author":"Potzernheim","year":"2012","journal-title":"Biochem. Systemat. Ecol."},{"key":"10.1016\/j.jep.2026.121947_bib38","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.sajb.2023.12.013","article-title":"Cholesterol lowering acitivity and vasorelaxant effect of ethanol extract Piper aduncum leaves in hypercholesterolemic wistar Kyoto rats","volume":"164","author":"Rachmaini","year":"2024","journal-title":"South Afr. J. Bot."},{"issue":"3","key":"10.1016\/j.jep.2026.121947_bib39","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1046\/j.1440-1746.2001.02433.x","article-title":"Diazoxide, a K(ATP) opener, accelerates restitution of ethanol or indomethacin-induced gastric ulceration in rats independent of polyamines","volume":"16","author":"Rahgozar","year":"2001","journal-title":"J. J. Gastroenterol. Hepatol."},{"issue":"4","key":"10.1016\/j.jep.2026.121947_bib40","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1177\/0960327119895559","article-title":"Ethanol-induced gastric ulcer in rats and intervention of tert-butylhydroquinone: involvement of Nrf2\/HO-1 signalling pathway","volume":"39","author":"Rahman","year":"2020","journal-title":"Hum. Exp. Toxicol."},{"issue":"9","key":"10.1016\/j.jep.2026.121947_bib41","doi-asserted-by":"crossref","first-page":"11327","DOI":"10.3390\/molecules180911327","article-title":"Dillapiole, isolated from Peperomia pellucida, shows gastroprotector activity against ethanol-induced gastric lesions in Wistar rats","volume":"18","author":"Rojas-Mart\u00ednez","year":"2013","journal-title":"Molecules"},{"issue":"9","key":"10.1016\/j.jep.2026.121947_bib42","doi-asserted-by":"crossref","first-page":"3169","DOI":"10.3390\/nu13093169","article-title":"Propolis and its gastroprotective effects on NSAID-induced gastric ulcer disease: a systematic review","volume":"13","author":"Ruiz-Hurtado","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.jep.2026.121947_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.112440","article-title":"The gastroprotective effect of Yucca filamentosa standardized crude leaves extract versus its nano-cubosomal formulation in ethanol-induced gastric injury","volume":"137","author":"Salaheldin Abdelhamid Ibrahim","year":"2024","journal-title":"Int. Immunopharmacol."},{"issue":"12","key":"10.1016\/j.jep.2026.121947_bib44","doi-asserted-by":"crossref","first-page":"3581","DOI":"10.1080\/14786419.2024.2334323","article-title":"PPAR gamma agonistic activity of dillapiole: protective effects against diabetic nephropathy","volume":"39","author":"Shafi","year":"2025","journal-title":"Nat. Prod. Res."},{"key":"10.1016\/j.jep.2026.121947_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.jphotobiol.2019.111604","article-title":"Effect of the essential oils from Piper sp. and blue led lights in the enhancement of the antibiotic activity of drugs against MDR bacterial strains","volume":"199","author":"Silva","year":"2019","journal-title":"J. Photochem. Photobiol., B"},{"issue":"2","key":"10.1016\/j.jep.2026.121947_bib46","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.vetpar.2009.06.006","article-title":"Toxicity of Piper aduncum L. (Piperales: Piperaceae) from the amazon forest for the cattle tick Rhipicephalus (Boophilus) microplus (Acari: ixodidae)","volume":"164","author":"Silva","year":"2009","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.jep.2026.121947_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.117542","article-title":"Aqueous extract of the bark of Uncaria tomentosa, an Amazonian medicinal plant, promotes gastroprotection and accelerates gastric healing in rats","volume":"321","author":"Simomura","year":"2024","journal-title":"J. Ethnopharmacol."},{"issue":"4","key":"10.1016\/j.jep.2026.121947_bib48","article-title":"Effects of non-steroidal anti-inflammatory drugs (NSAIDs) and gastroprotective NSAIDs on the gastrointestinal tract: a narrative review","volume":"15","author":"Sohail","year":"2023","journal-title":"Cureus"},{"issue":"Pt 2","key":"10.1016\/j.jep.2026.121947_bib49","article-title":"Gastroprotective potential of the aqueous extract of nine-steaming and nine-sun-drying processed Polygonatum cyrtonema Hua against alcoholic gastric injury in mice","volume":"338","author":"Sun","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121947_bib50","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.sajb.2024.05.027","article-title":"Anti-oxidative stress and gastroprotective effect of Tri-Tharn-Thip tea against ethanol-induced gastric ulcer in rats","volume":"170","author":"Wetchakul","year":"2024","journal-title":"South Afr. J. Bot."},{"key":"10.1016\/j.jep.2026.121947_bib51","article-title":"Gastric ulcer","author":"Woolf","year":"2026","journal-title":"StatPearls"},{"issue":"5","key":"10.1016\/j.jep.2026.121947_bib52","doi-asserted-by":"crossref","first-page":"3758","DOI":"10.3168\/jds.2017-13872","article-title":"Protective effect of bovine milk against HCl and ethanol\u2013induced gastric ulcer in mice","volume":"101","author":"Yoo","year":"2018","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.jep.2026.121947_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2024.126860","article-title":"High-fidelity imaging of drug-induced acute gastritis by using a fluorescent and photoacoustic dual-modal probe with good stability in stomach acid","volume":"281","author":"Zhang","year":"2025","journal-title":"Talanta"},{"key":"10.1016\/j.jep.2026.121947_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.157090","article-title":"Edible ultrasmall polyphenolic nanozymes for oral treatment of alcohol-induced acute gastritis","volume":"500","author":"Zheng","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.jep.2026.121947_bib55","article-title":"Gastroprotective effect of gallic acid against ethanol-induced gastric ulcer in rats: involvement of the Nrf2\/HO-1 signaling and anti-apoptosis role","volume":"126","author":"Zhou","year":"2020","journal-title":"Biomed. Pharmacother. Biomed. Pharmacother."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126008019?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126008019?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T02:23:13Z","timestamp":1783131793000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874126008019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":55,"alternative-id":["S0378874126008019"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2026.121947","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gastroprotective action of Piper aduncum L. leaf essential oil mediated by \u03b12-adrenergic biochemical pathways, nitric oxide synthase, and sulfhydryl compounds","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2026.121947","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"121947"}}